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About The Vines Village
The Vines Village is the perfect destination to explore, taste and relax amongst 4 acres of expansive tranquil landscaped lakeside grounds.
A short 10 minute drive from Blenheim we are perfectly located amongst the world famous 'Golden Mile' in Marlborough's wine country.
Here you can discover the award winning Whitehaven Wines Cellar Door, sample Golden Mile Brewing's Beer & Roots Dry Gin (produced on-site), taste Marlborough's best produce at the Vines Village Cafe & Deli (named 'Best Sustainable / Environmental Business' at the NZ Hospitality Awards), enjoy Appleby Farms Ice Cream & Taylor Pass Manuka Honey, shop at The Merino Store & Quilters Barn for that something special and explore the world of up-cycled furniture with Pru & Co.
Check out the region by bike with Explore Marlborough bike hire or just enjoy a moment or two in the Outdoor Theatre. With loads of free parking for buses, camper vans, cars with trailers and bikes all are welcome.
The Vines Village is an essential stop on your journey through Marlborough and we look forward to seeing you soon.
The Vines Village Cafe & Deli is Marlborough's award winning favourite casual dining destination, a fresh and wholesome cafe specialising in nourishing breakfasts, fresh Supreme coffee, tasty lunches and afternoon drinks. With a large kitchen garden, fruit trees and adjoining deli and Tap Room, the VVC aims to use food from sustainable, ethical sources and offers a broad range of food styles and organic beverages (try the local organic kombucha and other wellness tonics), green smoothies and fresh garden salads.
The Vines Village is the artisan hub of Marlborough with a range of boutique shops offering carefully selected Marlborough produce and gifts. From the eco-friendly and gourmet delights of the Deli to the Merino Store's high quality woollen offerings or the Quilters Barn's wide range of art and craft supplies. There is also the opportunity to up-cycle your favourite piece of furniture with Pru & Co or maybe pick up a voucher for that special person so they can choose from the the wide variety of shops at the Vines Village.
The Vines Village is the perfect location to start or finish your day of activities and adventures in Marlborough.
Check out coming events at Vines Village or the extensive day to day offerings.
Ask us any time for suggestions as we love showing off the best Marlborough has to offer.
Add to your New Zealand experience by staying on-site at The Vines Village in Marlboroughs' wine country. Hire a bike for the day and explore the many neighbouring wineries and relax in the fresh water gas-fired hot tub at the end of the day with a Vines Village Deli pack of goodies and a complimentary bottle of wine.
The Vines Village is the perfect venue for weddings, special occasions or meetings.
Make the most of the beautiful landscaped grounds, cafe and boardroom and be sure to ask us any questions about planning your private function at the Vines Village.
The Vines Village, 193 Rapaura Road, RD3 Marlborough 7273
New Zealand
Open 7 days
Please check with individual stores for opening times
10 April GOOD FRIDAY - CLOSED
13 April EASTER MONDAY - OPEN from 12.30pm
9AM - 4:30PM (Easter - Labour Weekend)
Karen (Office): email@example.com
Jeff (Owner): email@example.com
Tim (Owner): email@example.com
Rae (Cafe): email@example.com
Check out what is happening at Vines Village right now!
For a full calendar of family friendly events
follow us on instagram and keep an eye on vinesvillagecafe.co.nz/events to keep up to date with all the latest events and activities.


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As I recently migrated my Home Assistant instance to my good old Intel NUC, I needed a new media center. I also promised myself to buy a new Game PC after completing my bachelor's study program while working fulltime. What if I could combine these two things together, while the screens are in different rooms?Continue reading "My New Centralized Gaming PC using HDMI over UTP"
Category: Windows
Azure Bastion changes everything!
This week Microsoft quietly released some information about a new Azure solution called Azure Bastion. Azure Bastion acts as a gateway between a Virtual Machine in Azure and your session in the Azure Portal. This means that without assigning a Public IP address, you are able to connect to your Azure Virtual Machine through the Azure Portal. No Remote Desktop environment or jumpbox needed. Azure Bastion is currently in Private Preview.
Windows Servicing Plans vs Task Sequences
On Twitter I asked the following to David James (Director of Engineering, ConfigMgr, Microsoft) and Johan Arwidmark (CTO @ TrueSec):
Continue reading "Windows Servicing Plans vs Task Sequences"
Update Windows 10 with SCCM/WSUS only by defeating Dual Scan
With Windows 10 1607, Microsoft introduced Dual Scan functionality, which allows the computer to connect with Microsoft Updates besides using WSUS or SCCM. Steve Henry from Microsoft: "It is for the enterprise that wants WU to be its primary update source while Windows Server Update Services (WSUS) provides all other content." I've seen various blog posts not covering all the steps I had to take to ensure Windows only looks to SCCM/WSUS. Especially covering Windows 10 deployments with System Center – Configuration Manager.
Continue reading "Update Windows 10 with SCCM/WSUS only by defeating Dual Scan"
*driver* did not meet the Store signing level requirements – Windows 10 Code Integrity
This error message is related to Device Guard Code Integrity in Windows 10 and shows up in the Event Viewer under the Code Integrity folder. As of writing this article, the error message is not described in online documentation of Microsoft.
Continue reading "*driver* did not meet the Store signing level requirements – Windows 10 Code Integrity"
Windows AutoPilot – New Features
With the Windows 10 Creators Update, Microsoft introduced Windows AutoPilot. Windows AutoPilot is a service which allows users to enroll their device with the Intune/Azure AD tenant of the organization during the Out-of-the-Box (OOBE) experience of Windows 10. By using Windows AutoPilot, organizations can dramatically decrease the time needed to configure a new device. During Microsoft Tech Summit 2018 in Amsterdam, Michael Niehaus announced some exciting new features which I will discuss in this blog post too.
Stable Windows Builds or Yearly Releases
With Windows Servicing, Microsoft is forcing consumers and businesses to upgrade to a Windows 10 Build twice a year. Theoretically you could go for one build per year, but that forces you to upgrade to a new build within 6 months. Otherwise you will end up without support for the old build.
This introduces quite some issues within both SMBs and large organizations. Recently a friend asked me about a recent printer that stopped working. The printer was 2 months old and from a large vendor. I directly checked the build of the machine and yes, it was recently upgraded to the Fall Creators Update. The printer was identified as an "Unknown USB Device". Updating the driver of the printer didn't help. Luckily the Technical Support was responding quickly to help, but this means manual processing of orders for the next couple of weeks. Yes I can revert the machine back to the old build, but will that fix the issue or create more issues? And because it's not a Windows 10 Enterprise machine, Microsoft will try to update the machine later on.

subset: commoncrawl


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It is very common to hear that people who already are in a relationship are getting involved with another person. psychologists suggest many reason behind this action. But do we really understand our deepest desires? Maximum time we ignore this kinda embarrasing questions, which leads us to a great confusion and to a massive misunderstanding that can destroy your existing relationship or even you. But people love to have a crush. And they also love to fall in a problem. So here we have some expert tips just to handle your situation without hampering your partner. Just remember The Crush is a need.
1. It's natural dude!
Though you have a guilty feeling inside, but it sometime can be true that the spoiler is a bit funnier or sexier or attractive than your partner. In that case you are not doing any crime. Mate, you are a human being not any social robot!
2. Dont lose yourself !
So now when we have understand that having crush other than your partner is a human job, now you have to controll yourself from getting blown away. Dont forget that it's how you behave in the face of temptation that reveal your character. And dont make it regular.
3. have a look at yourself !
Obsessive thoughts are the hallmark of an intense crush. It is a red flag. It indicates that the time has come when you need to examine yourself. Spend less time thinking about that cute guy at work and more quality time with your partner and make sure it's time spent laughing, talking, and confiding in one another.
4. Acknowledge your loneliness !
Keep your crush to yourself, but if you're feeling lonely or undesirable or just missing some affection from your significant other, that's information your partner should know.
5. Remember your good memories together! cherish them!
It is actually a good excercise. remembering good memories helps a relationship walk farther. Travel together. Laugh together. Spend a more time together. Communicate more. Don't shut down or shut him or her out when you're feeling isolated and confused, rather for the health of your union, draw your beloved closer and decide to take on the world — with all of its temptations, joys, sorrows and struggles — together.


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The 2015-2019 Strategic Plan for the City of London, speaks to 'Growing Our Economy' as one of the areas of focus to strengthen London's workforce. With an aging population and declining birth rates, creating increased supports for the attraction, retention and integration of Newcomers, including international students, foreign trained professionals and multigenerational immigrants, was identified by the City as a top priority for Londoners, City Council and Civic Administration.
Choose London – Innovative, Vibrant and Global: London's Newcomer Strategy is a community driven strategy, led by the City of London. It is the product of a broad consultation process with multiple stakeholders and statistical and literature reviews. This Strategy identifies three strategic priorities: Enhance Awareness, Facilitate Access and Active Engagement. Each of these strategic priorities is supported by the activities as set out in the work plan. The activities are aimed at creating a necessary drive towards meeting quantitative targeted outcomes relating to Newcomer attraction and retention to sustain and increase economic growth.
Although quantitatively meeting the labour and population growth needs of the city are key to ensuring healthy economic growth, it also important not to lose sight of the value of diversity of thought and a global outlook that Newcomers bring to the city. This enriches a society in so many ways beyond economics. There is also an opportunity to more effectively explore the skill sets that refugees bring with them and how those skill sets could be used to fill current labour market gaps.
Newcomer Strategy Appendices:
Appendix A - City of London Strategic Documents and Priorities
Appendix B - 1,2 & 3 Listing of Programs from December 2017
Appendix C - Community Consultation Participants
Appendix D - Community Consultation Summary of Feedback and Findings


text: By: Amanda Magnus DIY projects can be fun but also intimidating, kind of like starting a blog. But, like our first blog post and figuring out a new project we think it's best to just jump in, so here we go! When it came to refinishing furniture I had no idea what I was doing.… Continue reading Furniture Face-Lift


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Power Come From Behind And Walk Off On Kids Day
NIAGARA FALLS, NY. An exciting game for the Niagara Power today as they collected the walk-off win over the Hornell Dodgers on Kid's Day at Sal Maglie Stadium. Marcus Espinal had the winning hit in the bottom of the 9th inning, scoring Kolby Blanchard from 3rd base. After starter Nathan Hinkley tossed 5.1 innings of 1-run baseball, the Niagara Power got out to a 4-1 lead. Hornell would not go down easy, however, as they eventually took a 6-5 lead in the 8th inning. Down 6-5 in the 9th, Brett Lindsay reached first base to lead it off and the Power Rallied through their order to Espinal, who knocked in Blanchard for the 7-6 win.
The Power return to Sal Maglie on Saturday, June 16th when they play host to the Olean Oilers.


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Toolbox and methods
In this section, you will find a description of the tools and methods that were found to be useful during the research carried out throughout the T.E.E.N. project.
The tools are meant to act as inspirational reference points for you to adapt to your own needs, structures, projects, and desires. One of the most important things we have discovered throughout our experiences of working with teenagers is that there are no hard and fast rules, so by all means use the tools and methods we include here, but make sure you adapt them accordingly.
1. Pepy's Diary
We asked everyone involved in the project to create a diary in which they could not only reflect on the performances they had seen, but also on the wider world and how the performances they had seen might impact the public sphere. The goal was to intertwine ideas about life, theatre, writing, and public debate in order for the participants to understand that performances actually inhabit a public space and that there is no way to escape the spectator's subjectivity.
2. Three Questions on Criticism
Everyone involved in the project was asked to answer three questions about theatre criticism. This was used as a starting point to reflect on what theatre criticism is, who uses it, and how they go about it. This tool is especially good if you work with a group over a longer time, where you can go back and look at the starting point together with the participants as the project develops. The questions can also be answered in audio or video if the participant prefer other medias than writing.
3. Post-Show Questions
Questions were developed by the Stratagemmi Association who specialize in audience development, and the Codici Association that promotes research and social transformation. In the project, they were used by the Italian team to help them to express their feelings and opinions having journeyed to the Italian festival Santarcangelo dei Teatri in 2017, where they had met another group of teenage theatre-goers.
4. How to write about performing arts
The Norwegian web platform for teen critics ungestemmer.no was opened in 2012 by Norsk Scenekunstbruk. Since then critics, interviews and videos have been uploaded from all over the country. The tool How to write about performing arts was made by the Norwegian Union of Critics as a guideline for teenagers using the platform wanting to express their critical thoughts about their art experiences.
5. Hacking the Theatre
Every workshop began by watching a performance together. Groups then explored how they could form and express their opinions, and then produced a 'hack'. This was intended to allow and inspire to express themselves and comment on their experience in ways other than writing a review. For example, they might make a video that presents an idea about how the audience are let in and out, or they may offer suggestions about the production of supplementary learning materials.
6. Talking about Theatre
These tools were developed by Matthew Reason, Professor of Theatre and Performance in the Faculty of Arts at York St John University, and helps to initiate conversations about theatre from six different points of view. The tools were presented to the TEEN ambassadors during a workshop in the April festival in Denmark in 2017.
7. The Kitchen Table Format
The Kitchen Table manifesto was written by the teen ambassadors as a handbook for facilitators who want to host a Kitchen Table discussion. Whilst the content of the discussion is of course flexible, the format should remain consistent. The format has been growing into its form and has been presented at several festivals in Europe and Asia. The format will also play a major part in the TEEN 2 project that will be launched in 2019.
8. Experiencing Theatre
Questions about young people's habits and engagement as theatre-goers, as well as expectation and experience cards that can be printed, ready to use.
Pre knowledge
Two needs were identified as fundamental: increasing the knowledge about audience development's processes and about the target of the project. This led to organizing two workshops, one to develop expertise and a second one to train crucial skills for the development of the process.
Here you find one presentation developed by the Fitzcarraldo Foundation, and one by Codici Association. They were used during the training workshop for professionals at the TEEN projects kick-off meeting in 2016. they aimed to give the professionals common ground for further work on the theme.
For more information, please contact the Fitzcarraldo Foundation: Alessandra Gariboldi and the Codici Association: Stefano Laffi


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I am a visual artist and theatre-maker from Mayo, Ireland.
I have exhibited and performed all over Ireland.
I work in various roles including writer, performer, visual artist, set designer, scenic painter, costume designer, prop maker and stage manager.
I have a Bachelor's degree in Art from the Institute of Art and Design, Dun Laoghaire and a Masters degree in Stage Design (Set, Costume and Lighting design) from The Lir, Trinity College Dublin.
I am co-director of 4D Space a curatorial collective focused on promoting performance and live art in Ireland.
We hold events, exhibitions and workshops around the country and also self publish a zine called 'Taibh' which is a showcase of performance and live art happening around Ireland.
Contact: firstname.lastname@example.com


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Norm "Sugarbone" Sloan was an outstanding bass player and a true gentleman of our music scene. Transplanted to South Florida in 1969, "Sugarbone" quickly immersed himself into our then-burgeoning music scene. Well-versed in playing blues, country, standards, Top 40, R&B, classic rock, and jazz-rock fusion in the bar scene, Sloan was most recently an associate of Charlie Pickett and Bobby Tak. Originally from New York City and educated in that city's underground rock 'n' roll as well as Motown and soul, "Sugarbone" cast an impressive presence alongside his upright bass and his never-ending supply of hand-rolled cigars.
But whatever words I can muster now to remember the gentleman by, I think this quote from his MySpace page solidifies best the attitude and musical know-how that he represented for 62 years:
"As a teen I spent many days cutting class to go hang around Greenwhich [sic] Village. One such day as I walked into an upstairs restaurant on Bleeker [sic] & 6th known as the Tin Angel, I spotted Jimi slumped over in a drunken stupor. Noticing his white strat slipping off his lap, I ran over to grab it before it hit the floor. While shaking his shoulder I called out; Jimi, wake up! Later that afternoon my friends and I spotted Mickey Dolenz and Davie Jones strutting down McDougal Street. We jeered, shot them the bird and threw whatever we could pick off the ground at them. Oh Yes; I have been to Electric Ladyland and I am experienced."
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That you were, sir, that you were. And South Florida will miss you dearly.


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Brockton Basement Remodeling – 781-209-6639. If you are looking for the best Owens Corning basement finishing and remodeling experts in Brockton MA, call us right away. The Owens Corning basement solution will change your basement into a fabulous place for all your friends and family to have fun.
Our Owens Corning basement remodeling specialists will create the basement of your you've always dreamed would be your fun haven. 781-209-6639.
Basement Remodeling Contractors Brockton MA


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UDOH Office of Health Disparities (OHD) is pleased to announce the release of a new health video titled Health in 3-D: Understanding Diversity, Determinants and Disparities. Learn from local experts and community members as they share their expertise and their stories.
Health in 3-D is 28 minutes in length and can be easily accessed online. You may use it for customer service or diversity training and it can be used by individuals or groups.
Below are locations where you can find the assessment tools that OHD has developed. There are 3 options to choose from:
Utilize UTrain. Watch the video and follow step-by-step instructions at http://health.utah.gov/disparities/training/healthin3DUTrain.html. (For State of Utah Employees Only)
Participate as a Group. Use a cool app called Socrative Quiz App on smartphones, tablets and laptops. It provides immediate feedback to participants and tallies results for the group leader. Use this option at http://health.utah.gov/disparities/training/healthin3D.html.
Paper Quiz. Download the quiz at http://health.utah.gov/disparities/training/Healthin3DQuiz.pdf . When you're finished, go to the answer guide and see how you did.
If you have any questions, please contact 801-273-4140 or email firstname.lastname@example.com.


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Enter your Registered Email id
Enjoy the iconic style with exceptional quality, performance and comfort with these Ray-Ban Aviator RB3025 sunglasses for men and women. These timeless aviator silhouette is one of the best-selling pairs of sunglasses in the world, recognised by many for its classic design. Crafted in a strong, durable silver metal the frames combine functionality and style. You won't compromise on comfort with the RB3025 Aviator, made with nose pads and temples tips. To complete these highly popular Ray-Bans, they are complemented by silver mirror lenses, bringing 100% UV protection. Buy designer sunglasses online cheaper than the high street and other online retailers when you shop online at FeelGoodContacts.com.
Mon - Fri: 8:00am - 9:00pmSat - Sun: 9:00am - 5:30pmBank Holidays: 9:00am - 5:30pm


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We're into Community
It's hard to beat drinking great beer straight from source sitting among the stainless steel vats full of beer. Our tap room is a community space with a friendly, relaxed atmosphere. It's open all year round and has become a hub for good times and good vibes. We like to keep it fresh so there's always something new happening: pop ups, free family entertainment, silent discos, workshops and loads more.
Our friends from Brick Pizza have their wood-fired oven at our tap room and on Sundays we like to celebrate and promote local street food pop ups. Since opening the tap room in March 2018 "weekends under the arches" have become a thing! Get in touch for large group bookings, otherwise its just first come first served.
– Oh, and dogs and kids are almost mandatory!


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Nov 25
Posted by JP Feed
What better way to kill a game than with rules? Read the rest of this entry →
Posted in Sports
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Those who are mechanically-minded might want to try to fix their furnace themselves, especially if they've developed a problem that is quite common. But, the common furnace issues we outline here shouldn't be fixed by amateurs. Without professional knowledge, you will not be able to resolve these issues. What's worse, you may actually make things worse.
1. Why is There Water Coming Out of Your Furnace?
High efficiency furnaces are most likely to develop this problem because they use condensation to cool their exhaust before sending it out.
If you've found a puddle near your furnace's exhaust, your furnace condensate pump may not be working, there may be a leak in the condensation lines, or the furnace's secondary heat exchanger may be faulty. A professional can tell you which of these is the source of your problems.
Why You Shouldn't DIY: Furnaces, and the electrical equipment near them, are dangerous when wet. Without professional knowledge, you could electrocute yourself trying to fix the condensation problem.
Further, sometimes a condensation problem is so expensive to fix that you're better off getting a whole new furnace. If this is the case, asking a professional for their expert knowledge will save you money in the long run.
2. Why is there a Booming Noise coming from Your Furnace?
If your furnace is making a booming, rumbling, or "flexing" noise when it starts up, you're right to be concerned. Just like with the water mentioned above, there could be a few sources of this problem.
Your ducts may be too small for the size of your furnace, causing the metal to flex and ripple when the furnace comes on. Or, there could be a gas build-up before the furnace starts up, causing it to use up all the gas when it turns on, which makes the booming noise.
Why You Shouldn't DIY: As this problem may be from gas build-up, you shouldn't try to fix it yourself. The gas could fuel a fire, or exposure could put your health at risk.
Further, there are many other noises your furnace may make that could indicate other problems. It's important to have a professional confirm the problem so you don't waste time and money trying to fix the wrong thing.
3. Why Does Your Furnace Turn Off Early?
A furnace that starts up, but then turns off before your home has reached the temperature you've set is an indication that one of the furnace's internal components is likely damaged. Sometimes this is due to a sensor malfunction, which needs to be cleaned or replaced.
Or, the furnace may be hitting high temperatures, at which point a safety feature will switch it off to prevent fires and damage to the furnace.
Why You Shouldn't DIY: HVAC professionals will be able to pin point which part of your furnace is short-circuiting, or if there's a safety issue with the furnace. If you try this on your own, you may guess the wrong part, or let a safety issue go unchecked.
Ultimately, if you're wondering why there is water coming out of your furnace, or why it has other problems, it's wisest to call the professionals at ABW Halton ClimateCare for help.


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Recent Posts
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Category Archives: music
jimi hendrix 12 string blues
Posted in music Tagged 12 string guitar, jimi hendrix, jimi hendrix blues Leave a comment
my people hold on, the time has come
Posted in music Tagged civil rights movement, detroit, eddie kendrick, j dilla, jay dee, music of the 60's, my people hold on, revolutionary songs Leave a comment
south african hip hop & the global underground
SOCIETY AND ARTICULATES THE VOICE OF THE VOICELESS TO THE MASSES, IT ORIGINATES FROM AFRICA. i'm part of a movement. a youthful, peaceful spiritual revolution. socially conscious music, conquering the foolish/ mentality they usin to keep society from choosin/ its … Continue reading
Posted in art, music Tagged african hip hop, Angola, art, Cameroon, democracy, documentary about hip hop, egypt, ethiopia, ghana, government, hip hop documentary, hip hop in africa, hip-hop, Ivory Coast, Kenya, movies in africa, music, nigeria, politically active, politically aware, politically conscious, politics, revolution, Rwanda, Senegal, society, South Africa, Tanzania, uganda Leave a comment
native sun: accra city blues
see saxophones and scenery, ceremonies with trumpets travel through time take you all over the continent transforming the visual cortex of your brain synapses rearrange strengthening the bonds that once remained strong in the film and the song see the … Continue reading
Posted in art, music Tagged accra city blues, africa, africa vs. african american, african cinema, african films, african music videos, african-american, artists from africa who now live in america, blitz the ambassador, chicago, film, films about africa, films of africa, free your mind, ghana, ghanaian artists, ghanaian cinema, ghanaian music, ghanaian music videos, music, music video, new york, nigeria, short film, washington d.c. Leave a comment
My mind warps and bends floats the wind count to ten meet the twin Andre Ben. welcome to the lion's den. original skin many men comprehend I extend myself so you go out & tell a friend Sin all depends … Continue reading
Posted in music Tagged algorithm, alien, and, andre 3000, aquemini, atlanta, atlanta hip hop, big boi, dirty south, ethiopia, everyone, faith, galaxy, hip-hop, history of man, horoscopes, laws of the universe, lifestyle, math, mathematics, mc ren, me, music, nothing lasts forever, now, outkast, principles, rap, rap from atlanta, second son, sin, south, southern music, stars, sun, the sun, then, three suns, universe, us, you 1 Comment
Now see I'm livin just to die without most any reason so I keep on chasin paper 'til it's time to go, But should I really go for mine and put the clip all in the 9 Or stay at the … Continue reading
Posted in apocalyptic apotheoses, inspirational motivation, music Tagged freedom, freedom of speech, freedom of thought, krs-one, life, longevity, lyrics, songs, spirituality, survival, survivin 1 Comment


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Stand Sure Studio Genesys Framework Content for Unity 5/2017/2018/2019
Workflows for Real Time Rendering (Game Engine Development)
Free Content for the Unity 5/2017/2018/2019 Game Engine
Genesis Weather
Genesis Weather has been designed from the ground up to simulate a fairly realistic weather system per scene/game. Unlike all other weather systems you can find, Genesis Weather works for Any Planet, not just earth. You have complete control over how your weather should behave in your Scene/Game.
Genesis Weather also gives you fully functioning dynamic particle systems and audio that look and sound excellent. Since you have full source of everything you change swap out and change whatever you like. The choice is yours. Genesis Weather uses only minor shader adjustments to Standard Unity 5 shaders (Clouds/Stars are the exception). This means that during Unity updates there are far less chance of things breaking. Again, you have full source so chip away and change if you wish.
Quick Links
Genesis Hair Shader
Genesis Hair Shader is a High End Hair Shader that is extremely fast and handles lighting incredibly well. The only issue in Unity is since this is a 'Fade Mode' shader technique it does not receive shadows. However, with a ambient lighting control this is never really a noticed issue. There is also a Surface Shader version made with Amplify Shader Editor (ASE) that does receive shadows and looks 'Good Enough'. It does require some Photoshop/GIMP Gaussian Blur pizzazz but not too difficult.
- Unity 5-2017-2018 (All Versions. Created in 5.1.2). Does not require Pro
- Very fast 2-sided shader with excellent soft alpha blending
- Only uses a Diffuse Alpha (rgba) (PNG), and Normal Map (PNG)
- 2 Sliders to control the material for Wet, Dry, Plastic, Metal, and Marble. (Can be controlled by script)
- Works in all Unity Unity 5-2017-2018 rendering modes: Forward Gamma, Forward Linear, Deferred Gamma, Deferred Linear
Genesis Eyes
Genesis Eyes are both a custom Eye Mesh and a Shader. This is a High End Eye Shader that is extremely fast and handles lighting incredibly well. The pupils dilate based upon any ambient lighting and takes the most intense light to determine dilation. The size is configurable by script. All C# source scripts provided.
The eye textures are colorized by the color selector in Unity. This allows for unlimited colors of eyes. Four textures are included to show how they should look when prepared. The Light Mask texture is a little strange to make but I explain how step by step. Only 2 normal maps are ever needed and they are both provided here.
Quick Links


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"They say the life of a detective is full of mystery and intrigue... I wouldn't know, I'm a witer." Sound familiar? Then chances are you've seen Killing You... A Week Ago!. I always wanted to make something live-action with the premise, and KYAWA was really an exercise in exploring what could come from it while playing The Movies.
Meet Rick Mogan, wildly unsuccessful writer about to become a mildly successful detective. Not that he knows it of course. RMPI will be a series that follows Rick from his first day in his new home - the abandoned office space of a detective who's gone missing. He is soon thrust into his new career by a Mysterious Client who sets him to the task of tracking down the World's Worst Rapist!
2009 Production Diary
Hey everybody! 2009 for ICE means the production of Rick Mogan: Private Investigator. For real. We have the first episode totally scripted and tight, which isn't something we can often say. We've started shooting, editing as we go, and things are looking pretty good so far. We're shooting in HD, even! So here's what we've been up to...
Sunday 19 July 2009
Monday 27 July 2009
Saturday 1 August 2009
Sunday 2 August 2009
Wednesday 5 August 2009
Thursday 6 August 2009
Saturday 19 September 2009
Friday 27 November 2009
Thursday 10 December 2009
Monday 14 December 2009
2010 Production Diary
Sunday 28 March 2010
Monday 12 July 2010
Saturday 21 August 2010
2011 Production Diary
Tuesday 15 March 2011
I'm incredibly proud of our combined efforts - we really came away with a fantastic scene. The acting, the angles... it all came together very well in editing. I get the sense that we're all getting on to the same page as far as our vision for how it's all going to come together.
March 2011 (General)


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Most Popular
'8 Mile' Is Coming To Netflix This December
Eminem's Oscar-winning 8 Mile is coming to Netflix. As of 1 December it will be available to stream of the service and given that he's about to drop his new album Revival any day, you can imagine it's going to be popular.
Credit: Universal
I probably don't need to tell you that the film is based on Eminem's upbringing, following an aspiring white rapper named Jimmy 'B-Rabbit' Smith Jr. (Eminem), who lives in a trailer park in Warren, Michigan, and his attempt to launch a career in hip-hop.
Credit: PA Images
Eminem won the Academy Award for Best Original Song for 'Lose Yourself', the first rap song to do so. Eminem did not even attend the awards because he didn't think he stood a chance at winning. Instead, he fell asleep watching cartoons with his daughter Haili when the award was announced.
The news comes after Eminem was crowned the king of hip-hop.
According to Ranker, the best of the best is none other than Marshall Mathers, which says: "Numerous different skills and attributes all must come together to make a truly legendary MC. Obviously, a rapper must display a sense of rhythm and an ability to complement the beat in unpredictable and exciting ways.
Credit: BET Awards
"A gift for lyricism and vocabulary is similarly essential - you can have the flow of the century, but if the words don't come together to tell a compelling story or present a unique point of view, it's still not going to translate into a great hip-hop song.
"But of course, there's also an intangible element that elevates some rappers into the ranks of the greatest of all time."
Eminem dropped his latest single, 'Walk on Water', featuring Beyoncé, from his upcoming album, Revival, on Friday and as you might expect from the internet in 2017, his fans have been going over his lyrics with a fine comb, looking for hidden messages and meanings.
But it turns out that they need not have bothered, as the 45-year-old rapper was joined by producer Rick Rubin and journalist Malcolm Gladwell for a new 'Broken Record' podcast, with the three of them discussing the personal themes the new single deals with.
"When you start out in your career, you have a blank canvas, so you can paint anywhere that you want because the shit ain't been painted on yet," Eminem said.
"And then your second album comes out, and you paint a little more and you paint a little more by the time you get to your seventh and eighth album you've already painted all over it. There's nowhere else to paint."
Featured Image Credit: Universal Pictures
Topics: Hip-Hop, Netflix, eminem


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|Joe Morris explains the learning site idea where livestock are concentrated for a short period followed by a generous recovery period. In the background, the learning site has about 700,000 pounds of stocker cattle per acre.
|Rob Rutherford explains the notion of a holistic context for decision making as Joe Morris and JP move cattle from one small enclosure to another.
|Richard King talks about residual, litter, and recovery periods following trampling of the learning site.
The rancher-to-rancher project is modeled after Australian projects initiated by Graeme Hand and assisted by other Holistic Management educators in Australia. If you are a central coast California rancher and would like to participate, contact the Soil Carbon Coalition (info at bottom of page). Soil carbon baseline plots are an optional add-on.
Soil Carbon Coalition is a 501(c)3 nonprofit organization


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Learn more
Enjoy an evening of art and music in our local parks and public spaces. Artists, activities, and coffee truck will be at the park at 6pm*, concerts beginning at 7pm*.
Events will be cancelled in inclement weather.
For further information, please call 604.943.9437. You may also access information at Delta.ca/Events.
Please bring your own blanket or lawn chair.
Date & Time
Tu, July 30, 7:30pm*
Delta Concert Band
Sunshine Hills Park, North Delta
F, Aug 16, 7pm
Bradley Pedwell
Sungod, North Delta
Th, August 22, 7pm
The Karmichaels
Diefenbaker Park, Tsawwassen
Tu August 27, 7pm
Ben Lockwood
Social Heart Plaza, North Delta
*event at 6:30pm, concert at 7:30pm
Delta Music Makers
The Delta Music Makers are a 60 piece concert band, based in Delta, with a varied, audience-friendly program of music.You will hearfull band selections, instrument and vocal solos and trios.
Bossa Dias & Friends
Latin music for summer evenings.
Halifax Wharf Rats
Classic rock tunes featuring East Coast and Maritime music, Canadian folk and Irish and Scottish tunes.
Bocephus King
Bocephus King solo performance is heartfelt and inclusive, like a soul-drenched psychedelic jukebox. Using his acoustic guitar and vintage drum machines, sing along to songs you know, and some you don't.
A full concert band performing a wide variety of music for all ages.
Vancouver born Bradley is a one-man-band linking acoustic guitars, harmonies, loops andapowerful vocal.Expect a heavy dose of 90's and early 2000's nostalgia
Local Delta band performing world beat traditional pop music.
Ben Lockwood
Jazz and foot-tapping swing.
We are looking for visual artists to enhance our Concerts in the Park Series this summer! If you are interested in displaying your artwork and/or live painting in the park while the bands perform, please 604-943-9437.
All Events
Registration is open now! View the Winter Leisure Guide!


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Prep time: 20 min
Total time: 20 min
Yield: About 1.5-2 cups
Chocolate Avocado Pudding
- 2 medium size ripe avocados
- 2 Tbsp vegetable oil
- 1/3 cup agave or maple syrup (or honey for a non-vegan version)
- 3 dates soaked in warm water for 15 minutes and chopped
- 1/2 cup fair trade cocoa powder
- 2 Tsp vanilla extract
- 1/2 - 1 cup unsweetened original almond milk or similar non-dairy milk
- Add ingredients to a blender or food processor in this order: oil, dates, honey, vanilla, half your non-dairy milk, avocados, cocoa powder.
- Blend for 2-3 minutes until smooth. Pour in additional non-dairy milk a little at a time until the pudding is the consistency you want. Remember it will thicken after chilling in the refrigerator.
- Spoon the pudding into ramekins or bowls, cover and chill in the refrigerator until ready to serve.


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We arrived in Santorini on the sixth day of our Greek adventure that started with 2 nights in Athens and 3 nights in Mykonos. We traveled with a group of four to celebrate the 40th birthday of our friend, Harah. Hopefully our itinerary and suggestions will help you plan an amazing visit to this beautiful island!
Since the sunset side of Santorini can be pretty pricey, we divided our stay on the island with two nights in Fira and two nights in Perissa Beach. Fira and Oia are more expensive areas than other parts of Santorini, but offer the iconic postcard views you've seen in photos.
TIP: Splitting your stay is a great option to save money. However, if you decide to do this, we'd actually recommend flopping the order that we chose. On our travel day to Santorini, our ferry was delayed and we didn't get there until pretty late. That meant our first day at the more expensive part of the island was cut a few hours short.
Day 1: Travel Day from Mykonos to Fira, Santorini
Ferry from Mykonos to Santorini – Our ferry to Santorini was supposed to depart before 2:00 pm, but got delayed for several hours. We took Hellenic Seaways Highspeed 7 booked through Let's Ferry. Getting on the boat is kind of crazy and fast so be ready to board when your ferry arrives!
The ride itself was pretty enjoyable. I had worried about getting seasick, but didn't have any issues.
Dinner at Argo Restaurant – After checking into the Majestic Hotel, we showered and headed out for dinner. We were starving! Argo is a cute spot in Fira that with a great view of the caldera. It would be great at sunset, but it was long past that time when we arrived.
We ordered a bottle of Chardonnay with our meal (the first local Chardonnay we came across on a menu in Greece) and it was really good!
Aestas bar – After dinner, we headed to Fira to enjoy the nightlife. The bartenders at Aestas make unique handcrafted cocktails and the DJ mixes really good music. The cocktails are not cheap here, so just keep that in mind.
Day 2: Fira, Santorini
Morning Hike from Fira to Oia – Start the day early and hit the cliffside trail for a hike from Fira to Oia. Depending on how many stops you take, the hike could take anywhere from 2 1/2 to 5 hours.
Lunch in Amoudi Bay – You'll be ready for a good lunch after the hike and Amoudi Bay is a picture-perfect spot for a meal. We ate at Sunset Taverna, but were told that all of the restaurants are good in the area. The restaurant will also call you a taxi back to your hotel if needed (just give them a heads up before you finish eating).
Afternoon by the Pool – Many of the hotels in Fira and Oia have fantastic pools (some with a view of the caldera). After the long hike, you'll probably want to relax for a bit before heading out on the town for dinner and nightlife.
SantoWines at Sunset – We'll start by noting that the sunset is incredible from this winery. It is very popular in the evening, so make sure that you make a reservation. We didn't feel that the service matched up to the expectation, but the view made it worth the visit.
As far as the wines, SantoWines has a good selection. You can order up to 16 wines for tasting. Naturally, we went all in!
Dinner at Naoussa – If you like live music, you might enjoy hearing the Greek musicians at Naoussa. This is also the only restaurant in Greece where we also saw (and participated in) plate smashing. Plate smashing is not really common today and it's more of a tourist thing, but if you want to see it, this is an option.
Day 3: Fira and Perissa Beach
Morning Shopping & Baklava in Fira – We spent the morning wandering around Fira before moving to Meltemi Village hotel in Perissa Beach.
There is an adorable sweets shop in the town that I'd had my eye on for the last two nights. WC and I stopped by in the morning and picked up some baklava to go. We snacked on the dessert as we wandered the shops in search of our favorite souvenirs.
Sunset Cruise with Santorini Sailing – This was another highlight of our visit to Santorini. To thank us for celebrating her birthday with her in Greece, our friend treated us all to a cruise on the Dreamcatcher catamaran. The tour company is Santorini Sailing and the cruise lasts about 4 1/2 to 5 hours.
The catamaran sails into the Caldera giving you great views of the red and white sand beaches. It also visits the "hot springs," but take note that these are not your typical hot springs. It might be a little warmer than the rest of the water, but definitely not "hot." WC, of course, jumped right in, but most of us stayed on board and just enjoyed the view!
Beer and wine are provided throughout the cruise and the crew also serves a delicious BBQ dinner just before sunset. While those daytime views are great, the sunset is definitely worth waiting for!
Day 4: Perissa Beach, Santorini
Vineyard Tour at Estate Argyros – If you really enjoy wine, Estate Argyros offers a much more authentic tasting experience. We started our day with a vineyard tour and wine tasting.
Santorini Brewing Company – Right next door to Estate Argyros is Santorini Brewing Company so (of course) we followed up our wine tasting with a beer tasting!
Inside you can taste a handful of their craft beers. You can then purchase some for "take-away." You can't drink them inside the building, but you once you're outside. We hung out on the front steps to enjoy them.
Dinner at Mezzo – This was probably the best meal we had in all of Greece. Everyone at our table ordered different menu items and we shared everything. There was not a single dish that we didn't like!
Plus the view at sunset is phenomenal!
Day 5: Perissa Beach, Santorini
Relax on the Black Sand Beach – We spent the morning relaxing on the black sand beach in Perissa.
WC braved the water, but I thought it was way too cold!
Evening Flight Home – This was the worst part of our Santorini visit: saying goodbye!
Enjoy our blog post? Pin it to share with others!


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22 Tart and Tangy Grapefruit Recipes ...
If you've never looked for grapefruit recipes, you are really missing out. Grapefruits is great because they taste good, but are also low in calories and high in nutrition. You can do lots of things with a grapefruit, which will give you new and tasty things to enjoy for meals and treats. Luckily, grapefruits aren't that expensive and they are easy to find so you can satisfy a craving anytime. Check out these tangy grapefruit recipes and get ready for a whole new perspective on this fruit.
1. Flavored Water
Via Effortless Weight Loss - Get ...
Many experts say that flavoring your water is a great way to ensure that you're getting enough every day. Grapefruit slices are the perfect choice.
2. Cellulite Eraser
Via Cellulite Eraser — Juicing For ...
Whether or not this drink gets rid of cellulite is debatable, but the taste makes it worth a try.
3. On Its Own
Via How to Peel a Grapefruit ...
Of course, you can't go wrong by enjoying a pile of grapefruit segments on their own. yum!
4. Grapefruit Basil Sorbet
Via Grapefruit Basil Sorbet - A ...
This refreshing concoction is the perfect ending to any meal, even if it isn't hot outside. You'll be addicted in no time.
5. Candied Pink Grapefruit
Via Candied Pink Grapefruit! + The ...
Be careful with this - it is really hard to stop eating it once you get started.
6. Citrus and Pomegranate Salad
Via 8 Delicious and Vitamin Rich ...
Doesn't this make your mouth water? It would be great with yogurt for breakfast. Or as a side dish for lunch.
7. Grapefruit Soda
Via Grapefruit Soda... or Cocktail
Get ready because this tasty soda drink is going to make your mouth pucker with every sip.
8. Baked Grapefruit
Via Clean Eat Recipe :: Simple ...
Even if you don't usually like grapefruit, you will love it prepared like this.
9. Champagne Punch
Via New Years Eve Champagne Punch ...
Champagne is the perfect backdrop for showcasing the delicious flavors of a grapefruit. And it looks really pretty too!
10. Arugula, Grapefruit and Toasted Coconut Salad
Via Arugula, Grapefruit & Toasted Coconut ...
Impress anyone you cook for with this healthy and yummy salad.
11. Grapefruit, Avocado, and Shrimp Salad with a Balsamic Reduction
Via Grapefruit, Avocado, and Shrimp Salad ...
The name says it all. I'd like to dig right in and eat this whole thing. What about you?
12. Broiled Grapefruits with Honey and Bananas
Via 29 Tasty Vegetarian Paleo Recipes
If you're looking for a healthy and delicious dessert that you can enjoy guilt free, this is the recipe for you.
13. Pink Grapefruit Breakfast Smoothie
Via 8 Popular Powerhouse Smoothies | ...
If you've never thought to put a grapefruit in your smoothie, now is the time to change all that. You can also use grapefruit juice.
14. Pink Grapefruit Sandwich Cookies
Via Pink Grapefruit Sandwich Cookies | ...
Add grapefruit juice to cookie fillings of frosting for delightful flavor that no one will expect.
15. GIN and GRAPEFRUIT COCKTAIL
Via Gin and Grapefruit Cocktail: 1970s ...
This drink is so pink and lovely. It tastes heavenly too!
16. Warm Grapefruit Tea Recipe
Via Warm Grapefruit Tea Recipe | ...
Soothe frazzled nerves at the end of the day with a nice pot of this stress relieving tea.
17. Avocado and Grapefruit Salad
Via Avocado and Grapefruit Salad Recipe ...
This is totally simple, but full of flavor, color and nutrition. You just can't go wrong.
18. Citrus Quinoa Chicken Salad
Via Citrus Chicken Quinoa Salad. - ...
You are going to love the way that grapefruit and quinoa taste when paired together.
19. Grapefruit Marinade
Via Grapefruit-and-Sugar-Rubbed Pork Tenderloin | SAVEUR
The juice of a grapefruit is perfect for creating a citrus flavored marinade for beef. It also works for chicken and salmon.
20. Coconut Panna Cotta Topped with Grapefruit
Via Calling All Spoons: 20 Palate-Pleasing ...
This crowd pleasing dessert is refreshing, creamy and full of taste. You will love it so much you might have two!
21. Lobster Salad with Grapefruit and Avocado
Via Lobster Salad with Grapefruit & ...
I'd eat this fr lunch every day if I could. Would you?
22. One Bowl Pink Grapefruit Bars
Via One Bowl Pink Grapefruit Bars ...
If you love lemon bars, you will adore these grapefruit bars. Everyone is going to want the recipe.
Do you eat grapefruits? Who knew you could so many things with them? Which one is making your mouth water?


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Clever Clownfish
Welcome to Year 2!
Your Teacher
My name is Miss Denny and as you know I will be your teacher this year. I will be supported by Miss Owen and we are very excited to begin our adventure together!
Learning in Year 2
Our topic this term is called All Aboard! We will go on a journey to discover what it is like to live in different places around the world. We will learn about different modes of transport and our history learning will be focussed on The Titanic. We will also study the different plants and animals that live in the ocean and learn how to look after the seas around the world. We are very excited to show you how to look after fish using our class pets too!
During our Maths lessons we will be developing our understanding of place value in 1-digit and 2-digit numbers. We will also be adding and subtracting numbers using concrete objects, pictorial representations and mentally. We will be developing confidence to solve problems by applying our mathematics knowledge in a variety of situations.
During our English lessons, we will be reading a range of exciting fiction, non-fiction and poetry texts. We will use a variety of texts related to our topic to widen the vocabulary in our writing. We will write in complete sentences for a range of contexts and purposes, using adjectives, adverbs and conjunctions. We will also develop our understanding of word classes and sentence types and use these to improve our writing.
Important Days
PE lessons will take place on a Monday and Wednesday. Please ensure your child has a complete PE kit (dark blue/ black shorts, plain white t-shirt and black pumps) that is clearly labelled in school at all times. Earrings should also be removed before our lessons.
Homework will be sent home on a Friday to be completed for the following Friday. Please spend a few minutes each night learning your spellings for your test.
To support your child with his/her English understanding, please practise writing sentences, including adjectives, adverbs and conjunctions. This could be done by completing a diary of his/her weekend, describing a character in their favourite book or writing a short story for example.
To support your child with his/her Maths understanding, please practise answering addition, subtraction, multiplication and division problems to 100. This could be done verbally, using concrete objects or by answering written problems.
I have attached a list of useful websites your child could also use to support their learning:
Faith Assembly will take place on a Monday morning at 9am.
Praise Assembly will continue to take place on a Friday morning. Remember to work hard for your chance to be awarded one of our special certificates.
Thank you for your support. If you have any further queries or questions, please do not hesitate to contact me.


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Wilkinson Sword
RazorCut Pro Straight Bypass Pruner by Wilkinson SwordOur Price £19.99
Sale Price £13.99
Wilkinson Sword RazorCut Pro Leather Tool PouchOur Price £14.99
Sale Price £10.49
Wilkinson Sword Stainless Steel Plant DibberOur Price £9.99
Sale Price £6.99
Wilkinson Sword Carbon Steel TrowelOur Price £4.99
Sale Price £3.49
Wilkinson Sword Gardening Tools
Designed to make gardening easier and much more fun, the unique and innovative collection of Wilkinson Sword premium gardening tools help keep your garden looking great!
The Wilkinson Sword gardening tools range is a reflection of 100 years of cutting edge excellence Developed by British brand E.P. Barrus – a brand with over 90 years of trading experience – these tools and accessories provide you with premium quality that truly lives up to this beloved brand's name.
Mill Race Garden Centre is proud to stock a wide range of Wilkinson Sword gardening products. From shears to digging forks, we're sure you'll find exactly what you're looking for in this range.
As with all our products, the Wilkinson Sword collection comes with our no hassle returns policy and all orders over £50 can be delivered within the UK for free.
Wilkinson Sword Stainless Steel Tools
The stainless steel range of gardening tools are designed for both professional and home use. Each tool head is created with mirror polished stainless steel and ash handles – making them comfortable to use and durable whilst maintaining a stylish aesthetic.
For smaller jobs around the garden like weeding or repotting bulb and plants, the stainless steel weed grubber and transplanter trowel are ideal. As part of the stainless steel range – alongside various other handy tools – these garden essentials are made to last.
As some work may require more muscle power, tools such as the stainless steel border spade are ergonomically designed to help make the job a little easier. The spade is typically designed to be smaller than a traditional digging spade to help manoeuvre around smaller spaces and its ash handle is waterproofed to ensure it lasts.
Wilkinson Sword Garden Cutting Range
Engineered for high quality performance, the Wilkinson Sword range of cutting tools are suited for all cutting tasks and user preferences.
With a wide range of pruners, shears, loppers and saws available, you'll be able to keep your garden and hedges looking perfectly trim all year round!
For precise pruning tasks, try either the general purpose Anvil pruners or the RazorCut Comfort pruning snips – both of which result in clean cuts for flowers or woody growths.
To help trim down your hedges use the Serrated Hedge Shears to ensure powerful but effortless cutting. These shears are lightweight and its blades are made of carbon steel for guaranteed strength.


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LG digital makes it our mission to protect privacy, a fundamental human right. We have been providing offshore web hosting and anonymous web hosting services since the year 2000. We are one of the most experienced offshore web hosting companies in the world with 8 offshore locations, own Anti-DDoS Attack network, thousands of dedicated servers, IP addresses, ICANN appointed .com domain registrar and in-house technical support working 24/7 to monitor all your web services. We provision, protect and secure your offshore web hosting needs. We have offshore VPS hosting, private email hosting, bitcoin hosting and all the tools you need to secure your identity. Sign up your web services with lg digital today!


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We are 'Advancing tomorrow's medicines' and making a real difference to the world in which we live. At Fujifilm Diosynth Biotechnologies, we partner with our clients to deliver recombinant proteins, viral vaccines and gene therapies to patients. As a Contract Development & Manufacturing Organization (CDMO), our focus is to combine technical leadership in cell culture, microbial fermentation and viral vectors with world class GMP manufacturing facilities to advance tomorrow's medicines. We seek candidates with proven ability to work independently and collaboratively to achieve optimized strategies, and execution programs with the ultimate goal of delivering products that transform the lives of patients.
We are seeking a highly motivated individual to join us as a QA Technical Specialist in our Contract Manufacturing site located in Research Triangle Park, NC.
Primary responsibilities will be to support QA Supplier Management and Material Disposition for the facility. CQA is preferred. Approximately 25% travel required.
Essential Functions and Duties:
- Conduct, coordinate and facilitate external audits and follow-up activities for various types of suppliers including, but not limited to: materials, contract laboratories, service providers.
- Develop audit reports, follow-up letters and other communications to suppliers. Provide on time follow-up to QA management regarding audit findings. Ensure suppliers have appropriate CAPAs in place for any GMP deviations found.
- Prepare Supplier packages for QA management approval
- Manage Supplier Change Notifications
- Perform review and QA disposition of materials
Minimum Education Requirements
Desired Experience
- 6+ years of applicable experience
FDBU works with technical data, technology and materials that are subject to U.S. export laws and regulations. This position will require access to technical data, technology and source code that is controlled under U.S. export laws and regulations, including but not limited to the International Traffic in Arms Regulations at 22 C.F.R. Parts 120 – 130 and Export Administration Regulations in 15 C.F.R. Part 730 – 774, as may be amended. To conform to these laws and regulations, applicants must be U.S. citizens, lawful permanent residents of the U.S., protected individuals as defined by 8 USC 1324(b)(a)(3) (i.e., asylees and refugees) or otherwise eligible for an export authorization from the U.S. Department of State or U.S. Department of Commerce. Offers of employment will be contingent on the Company's ability to secure an export authorization. FDBU is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status, sexual orientation, gender identify or any other protected class.
FDBU is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status, sexual orientation, gender identify or any other protected class.


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Mathematics 11 Systems of Linear Inequalities
Specific Curriculum Outcomes
RF01 Model and solve problems that involve systems of linear inequalities in two variables.
RF01 Model and solve problems that involve systems of linear inequalities in two variables.
RF01 Activities
- Starting at the End (Linear Inequalities) from I Speak Math - 7th grade students knit scarves for patrons of the Mooresville Soup Kitchen every year during the holidays. To begin linear inequalities Julie Reulbach proposed a business. Students were going to knit scarves and afghans to sell, and donate the proceeds to charity. A description of this activity using Desmos is included in a webinar from Eli Luberoff, the creator of Desmos.
- Representing Inequalities Graphically from Mathematics Assessment Project - Students work collaboratively, in pairs, on a game. One student decides on the position of a 'target point' on a coordinate grid and gives clues in the form of algebraic inequalities (e.g. 3y + 2x ≤ 12). The other student uses these clues to find the location of the target point. There is a strategic element to the game: what are the best clues to give, so that the target may be found quickly?
- Systems of Linear Inequalities Polygraph Desmos Activity from Jennifer Eaton - This Custom Polygraph is designed to spark vocabulary-rich conversations about systems of linear inequalities. Key vocabulary that may appear in student questions includes: shade, region, above, below, overlap, solution, intersect, and parallel.
- A Better Question from Heather Kohn - Heather asked her students to find similarities and differences between a system of equations and a system of inequalities. She made the activity into a debate. Instead of asking her kids to find differences, she asked them to find the biggest difference between the systems. Likewise, she asked the students to find the biggest similarity. Suddenly her room came alive with debate as students argued about which similarity or difference was the most significant.


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SPOILERS AHEAD! You have been warned.
Director: Terry Zwigoff
Stars: Billy Bob Thornton, Bernie Mac and Lauren Graham
MPAA Rating: Rated R for pervasive language, strong sexual content and some violence.
My Rating: 7/10
USA Release Date: Nov. 26, 2003
Running Time: 91 min | 88 min (Director's cut) | 98 min (unrated version)
Who would ever suspect a Santa Claus to rob a department store? This one does, with his 3-foot tall "elf" sidekick. This isn't an ordinary Santa Claus, with his massive drinking and swearing. One Christmas in Arizona proves to be problematic for them though, when Santa (Billy Bob Thornton) befriends a troubled kid and the security manager foil their plans. Marcus (Tony Cox) and his mail-order wife are too greedy for their own good, when they kill off the department store security manager (Bernie Mac) so they don't have to share half of their profits. That takes care of their problems, or so Marcus would think, unfortunately his "partner" is getting soft as he learns the true meaning of Christmas from the troubled fat kid he's been living with. The only option on Christmas eve is to pull off their last heist together, and kill "Santa" which backfires when the department store gets raided by the police.
Overall, this is a really good movie to watch around the holidays or whenever since it's just another comedy/robbery heist story. I'm sure I everyone has probably seen this before, but if you haven't go find it and check it out for yourself.


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Student scoops the pool at Geelong lamb carcase comp
Champion carcase and most successful lamb competition exhibitor, Sam Box from Maude.Lethbridge primary school student, Sam Box, Maude, has walked away from the Royal Geelong Show lamb carcase competition clutching a fist full of placegetter ribbons including the champion carcase award and the gong for the most successful exhibitor.
The 12 year old loves nothing more than mustering the family's 80 head ewe breeding flock on his motor bike and beat a number of seasoned-campaigners claiming award ribbons in each of the competition's three live judging divisions.
These included two sectional winners, a third placing plus two third placings in the carcase judging.
Sam, who farms for fun at Maude with his water-carter dad, Michael (and a bit of help from their good neighbour, Graham Johns) entered a team of three in each of the three weight divisions.
The Box family lambs which were Lucerne-fed were sired by Suffolk rams and bred from traditional Border Leicester Merino-cross ewes.
South Suffolk stud breeder, Barry Shalders, who farms of the edge of the laver flow at Derrinallum, won the Stock & Land sponsored grand champion award for the best pen of three lamb carcases.
The Shalders' lambs were South Suffolk-cross and bred from English Leicester Merino-cross dams.
This combination won Barry Shalders blue ribbons both live and on the hooks in the 16- 19.9kg trade weight class, and champion pen of three live as well as on the hooks.
A total of 81 lamb entries were judged in this year's competition with BA, HA & TR Jorgenson of Antwerp awarded the blue ribbon for best three heavy weight carcases weighing 24-29.9kg.
Laurie and June Forster of Sutherland gained the judge's nod for the best pens of three carcases weighing 20-23.9kg along with a second placing gained in the light weight, 16- 19.9kg carcase class.
This story Administrator ready to work first appeared on 苏州美甲美睫培训学校.
Posted in: 苏州美甲美睫培训学校


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Vivomixx® for seniors
During the aging process, many changes occur in the intestinal microflora due to the physiological reduction of lactobacilli and bifidobacteria and to a slower intestinal transit, resulting in reduced production of short chain fatty acids - the most important nourishment of the colonic mucosa.
During this period of life, a physiological decrease in immune defences, the onset of chronic diseases and consequent increased use of drugs, changes in eating habits are often observed.
All these situations cause an increase of the fermentation processes in the gut, with an overgrowth of potentially pathogenic bacteria, which are responsible for possible infections (for example, urinary tract infection) and intestinal disorders such as abdominal pain, cramps, excess gas, bloating, change in bowel habits such as harder, looser or more urgent stools than normal. These changes of intestinal microflora are also associated with alterations in the metabolism of sugar, fats and protein, resulting in possible development of diabetes and dyslipidemic disease, for example.


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If you're leaving your heart out on the track (or road, or even treadmill), you'll need a playlist that will help you kick up the pace! With high beats per minute (BPM) and upbeat hit music, this Tempo Run Playlist will help you train better. We asked three Vega Bloggers to share their favorite fast pace mixes with you in one playlist to rule all Tempo Runs.
*Consult your health care provider before starting any exercise regimen.
Note: Rocking this loud in your office to get pumped up before your afternoon run? Know that you might hear a couple of swear words in this playlist. These songs were chosen by our Mix-ologists as what gets them ready to rock their runs—expletives and all. These songs do not reflect the views or values of Vega.
If you don't know, now you know.
Listen on Spotify here
Meet Your Mix-ologists:
Sarah McCartan
Along with writing full-time, Sarah doubles as an avid long distance runner and vegan foodie. Her blog, Vegan on the Run, was born out of the desire to bring her vegan, writing, running, health-focused and wanderlust-filled worlds together under one roof.
Twitter: twitter.com/sarahkmccartan
Instagram: instagram.com/sarahkmccartan
Facebook: Facebook.com/veganontherun
Blog: veganontherun.org
Lottie Bildirici
Lottie is currently in school at the Institute for Integrative Nutrition as well as The Fashion Institute of Technology. She's passionate about running, biking, swimming and everything in between. "Food should taste good and make you feel good so follow me on my mission to show you how easy it can be!"
Instagram: @RunningonVeggies
Website: www.runonveg.com
Facebook: https://www.facebook.com/runonveggies
Steve Blaskie
Steven Oliver Blaskie is a father to a little girl, practices the holistic diet lifestyle and works full time as a lumberjack. A Boston Marathon qualifier and ultra trail runner, Steve thought it was time for a change of scenery from all the blisters and is now hitting the open water and highways to train for his first Ironman 140.6. When Steve isn't wiping dirty noses, rinsing kale or dodging falling trees, he helps raise money for Little Warriors Canada. This charity raises funds in aiding sexually abused children. Steve currently resides and trains in Ottawa with his daughter, Willow and their prized kale garden.
Instagram: https://instagram.com/zepphead
Twitter: https://twitter.com/zepphead
Abby Lauren
Abby's educational background with a Bachelor of Science in Nutritional Sciences and post-graduate degree in Biomechanics and Exercise Physiology has allowed her to use science as a tool for getting her clients in the best shape possible. Her training and nutrition focus varies from training clients for sports specific, weight loss, weight gain, muscle gain, muscle toning, cardiovascular health, cancer patients and those whose goal is to maintain a high fitness level. On her free time, Abby is the captain of the NBC Universal Triathlon team, an avid Marathoner for Fulfillment Fund Charity, a volunteer for Tree People, Children's Hospital LA and Girls on the Run LA. Abby enjoys yoga, reading, going to the beach, hiking and traveling. Visit Abby's website here


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Galip Akaydin
Research Article
Evalution of Antioxidant Activity of Various Herbal Folk Medicines
Author(s): Ece Miser-Salihoglu, Galip Akaydin, Emel Caliskan-Can and Sevgi Yardim-AkaydinEce Miser-Salihoglu, Galip Akaydin, Emel Caliskan-Can and Sevgi Yardim-Akaydin
The leaves of some plants are flamed and used to dress injured skin, to stimulate healing and to ward off infection. This study aims to determine antioxidant activities of Plantago lanceolata L., Plantago major L. ssp. major, Rubus hirtus Waldst& Kit., Sambucus ebulus L., Morus alba L. and Hedera helix L., which grown in Düzce and its surroundings and are used for anti-inflammatory purposes, and especially for wound-healing. The total phenolic compound of these plants was also evaluated. In order to determine the antioxidant compounds and antioxidant capacity of these plants, different in vitro methods. Resulting from our study, while P. lanceolata, R. hirtus, S. ebulus and P.major ssp. major had similarities in terms of phenolic compounds content, M. alba and H. helix were found to have relatively low content of phenolic compounds. In general, Plantago species and R. hirtus .. Read More»


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In 2001, Jill and I had our first child, Maeve. Two years later, our dynamic duo, Phoebe and Sophie, joined the Cutter clan. Phoebe always reminds us that she became a member first, since she pushed Sophie out of the way on her way out of the womb. Three kids in diapers—fun times.
At that same time, I had just started my business, and we decided that Jill would give up her career as a pharmacist to stay home with the kids. I am not going to lie to you; it was the epitome of stress. Stress on our sleep schedule, stress on our marriage, stress on our financials. But just like everything I do in life, I was all in. Don't get me wrong; those three little kids made me and continue to make me the happiest guy in the world, but, good heavens, it was a stressful time.
I was thinking back to that time recently, when I was counseling a buddy of mine, Bob, and his wife, Sara, who just had twins. The babies are their second and third children in as many years of marriage. Like we did years ago, now they have three kids in diapers. I told Bob that I remember those days and reminded him that just like anything in life, there is no gain without some pain.
But Bob and Sara are doing great. Tired, but great. As we talked, Bob mentioned having to pay off the hospital bills that he put on a credit card. Now, Bob has a pretty good job and he and his wife have good insurance, but there are still a lot of costs associated with having a baby (or two in his case). Bob explained that after some thought, he decided that the best solution was to put those charges on his credit card and attempt to pay it off before the interest rate would kick in and really start to hurt him.
You see, with this new frontier of health insurance, many of us now have to subscribe to high deductible plans to keep exploding monthly premiums down. This can also result in unforeseen out-of-network expenses. And it does not seem to be getting any better. So, I don't think it's a stretch to say that most people will, in their lifetime, come up against a medical bill, or bouquet of medical bills, resulting from a medical situation, that they simply do not have the financial resources to pay off immediately. So, this raises the question of what to do and how to handle these (usually) unexpected costs? Let me share with you a few ideas to ease in the recovery from these bills, if you find yourself recovering from any such medical issues.
First thing is to double-check your bills. This is no joke. Insurance coverage is not a simple thing to understand, and those bills, I believe, are designed to make it even harder to understand. Take the time to reach out to your insurance company. They can send you an itemized bill that makes things more clear and they can walk you through why and how you were billed for each item. Common mistakes can often be found; including things such as double billing, math errors, and charges for physician visits you never had. Those mistakes can add up to a significant amount of money that you should not be paying. I am not saying they are intentional in any way, but they do happen.
Another thing you can do is talk to your provider directly. Some hospitals and even some physicians' offices will give discounts if you pay upfront, and remove the headache of dealing with the billing office. Some will give you a discount for paying in cash or with a check, rather than a credit card. Also, you can usually work with your insurance company to set up a payment plan, if necessary. By explaining that you are unable to pay the bill in full, but offering to pay down what you can right away, can show good faith on your part and is a great way to negotiate a payment plan. And folks, sometimes these payment plans can be arranged without interest.
There are also a lot of organizations that help with hospital bills, especially when the bills are incurred to treat a specific illness, or you are at or under a certain income level. Check online, or ask your local hospital or doctor if there are any such charitable organizations or support programs that could help you with your bills.
Lastly, when you have exhausted all other options and are looking at the final amount due, charging it to your everyday, high interest credit card isn't your only option. Many doctors will accept "medical credit cards." They are designed to help you pay off large debts, resulting from medical and/or dental treatment, over time, often without interest for the first few months. It is important to be aware of those interest terms, however, as many of these cards are based on "deferred interest" terms, that charge high interest rates if you do not pay off the balance by a certain deadline. It's important to look at those terms and be realistic about whether you can pay off the bills before that deferred interest kicks in. If you are not confident that you can meet that deadline, you might be best served to put the charge on your regular credit card.
Medical bills can make those stressful medical situations, well, a bit more stressful. As always, there isn't a right or wrong way to handle those bills, but there are solutions that may help your individual situation. The important thing to remember is that, no matter what solution you choose, you have options.
Bob and Sara will be just fine. They have two beautiful and—more importantly—healthy, newborn babies. The next couple of years will be a bit of a blur with three kids in diapers, but I told Bob that each and every day it gets better and easier . . . in some respects. Well, unless you have three teenage girls!
Be vigilant and stay alert, because you deserve more.


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Tuition Free Universities in Germany
If African students are thinking that it's hard to study for free or in low-cost universities in a European country like Germany, they should think again. There are many tuition free universities in Germany that are even open for learning for international students. Germany caters to the education of the students through many government funded and non-government scholarships.
Many of the scholarships are for international students as well. So, African students can pursue their education and study in Germany with ease respectively. If they are eligible for any scholarship, then the education expense surely decreases or becomes none at all.
The universities in Germany offer undergraduate programs for free, so a huge number of international students come to Germany every year. Some programs or courses are provide in Germany. Yet, with ever-growing number of English-language programs in English, the international students can learn them in English as well.
An African student can enroll for undergraduate and graduate programs in different fields. A German institute or university has set pretty nominal tuition fees for MS Programs. Many of the teaching-free universities in Germany are funded through grants or loans. Yet, students have to bear the accommodation and food expense that varies with the place and the city.
A typical MS program in universities in Germany will require the African students to first clear the higher education entrance qualification exam. However, an undergraduate program level program completed in native university is considered eligible to pursue Master's program in Germany. Still, there are a few masters programs that are meant for those who have earned least number of credit hours in specific areas of research.
The applications for masters programs either get published on the official website or the forms are available in the respective college or university. There is a centralized service that keep tracks of the candidates and notifies those who meet all the criteria keeping into account their desired institutions. Further assessment of applications also takes place if required.
Not all of the universities use the centralized service to filter students. Those that do require the job seekers to complete their own program process. Each organization notifies them about the documents that are required and the software to process the application.
Normally, students are required to post an official duplicate of their educational qualifications, a passport sized photocopy, copy of their passport and the proof language effectiveness exam results. It is also possible that a credit card application payment gets billed.
Study Masters in Germany
If the students have completed their bachelor's program in Germany then, they can pursue their Master's program for free in different colleges.
The Master's programs in Germany are divided into two categories. One being consecutive and other being non-consecutive respectively. The former category focuses on academics knowledge that is achieved through a related bachelor-level program. The latter non-consecutive category focuses on those programs that lead to professional development.
Why choose Germany for Master's Program?
Germany is the ideal place to pursue Master's program because majority of the academic institutes are really cheap. Many students study in international university in Germany as well where world class programs are also offered in different areas.
If you as an African student are unsure of who to talk to and how to go about study in Germany, it's better to contact the admissions official of the concerned institute to get more information. In fact, you should reach us as we (Eurasia Institute) assist students with their educational solutions whether they are students, professionals and even for the educational institutes.
Many of the academic institutes especially Germany universities ranking is high in Europe due to their provision of modern and quality education at affordable expense as well. Just contact us and we will gladly help you in your educational endeavors.


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Meet Dom Testa's Galahad series, the first of which was published in 2004 -- seven years before ATU came out. Compare the summaries of Across the Universe and The Comet's Curse, and you'll see immediate similarities. And having read both, I can tell you that the similarities run true in the book. Teens get launched into space, in charge of a spaceship being sabotaged, while in the background medical science is developed.
And yes, I guessed the true antagonist from the moment he was introduced.
I'm not bashing or defending the books; my goal here is to point out that no idea is truly original. So when you're lauding a book, saying it's got a fabulously original premise is not the way to go.
Some more examples:
Veronice Rossi's Under the Never Sky (2012) and the MG dystopian A Crack in the Sky (2010) by Mark Peter Hughes (click titles to see Goodreads summaries).
I've read both these two as well, and I can tell you -- the worldbuilding (which was one of the main the selling points of UTNS around the blogosphere) is almost exactly the same: protected pods amidst a barren wilderness, using a grand disillusionment on the protagonist's part to fuel the central conflict. Click through the links up there to see the summaries, guys. See for yourself.
And finally, one forthcoming book that I haven't read compared with a classic: Eve Silver's Rush (2013) and Monica Hughes's Invitation to the Game (1991).
Click through, read the summaries, and tell me if you don't see a resemblance.
From my perspective, these matching premises are usually only a big deal or worth noting if the book is high-concept; contemporaries, for example, often bear similarities, which is to be expected. But the trouble starts once a premise's apparent originality becomes a selling point of a novel. In the end, we need to judge and promote books based on their actual quality. After all, a good premise never makes up for poor execution.


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Trial of Vinflunine Plus Capecitabine in Advanced Breast Cancer
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01095003
Recruitment Status : Completed
First Posted : March 29, 2010
Results First Posted : September 13, 2019
Last Update Posted : September 13, 2019
- Study Details
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
|Condition or disease
|Breast Cancer
|Drug: Vinflunine plus Capecitabine Drug: Capecitabine
|Phase 3
This multicentre, open-label, randomised, Phase III study will enrol 764 patients with advanced breast cancer who have previously been treated with or are resistant to an anthracycline and who are taxane resistant. Patients will be randomised in a 1:1 ratio to receive vinflunine plus capecitabine (Arm A) or capecitabine alone (Arm B).
Randomisation will be stratified according to a minimization procedure:
- Resistance to anthracyclines ("yes" versus "no"), Relapse ≤ 12 months in the adjuvant or neoadjuvant setting or progression ≤ 4 months in the metastatic setting,
- Karnofsky performance status ("90-100" versus "70-80"),
- Measurable disease ("yes" versus "no"),
- The number of prior lines of chemotherapy in the metastatic setting ("0" versus "1" versus "> 1") and,
- Study site.
Patients randomised in Arm A will receive:
- Vinflunine at the dose of 280 mg/m² on day 1 of each cycle every 3 weeks, over a 20-minute i.v. infusion and,
- Capecitabine which will be self-administered by the patient in an outpatient setting. Patients will take 825 mg/m² twice daily per os for 14 consecutive days beginning on day 1 of each cycle followed by 1 week of rest. A cycle of therapy is defined as 3 weeks.
For patients randomised in Arm B, capecitabine will be self administered by the patient in an outpatient setting. Patients will take 1250 mg/m² twice daily per os for 14 consecutive days beginning on day 1 of each cycle followed by 1 week of rest. A cycle of therapy is defined as 3 weeks.
The doses and timing of treatment will be modified based on toxicities experienced by the patient.
Patients will be assessed for toxicity, tumour response and progression at regular intervals during treatment. Patients will be evaluated for safety if they received any study drug. Laboratory values, adverse events and other symptoms will be graded.
Tumour response, progression-free survival and duration of response will be evaluated for all randomised patients. Tumour assessment is to be performed every 6 weeks (+/- 3 working days) from randomisation (regardless of the timing of treatment cycles) until disease progression is documented. Patients who discontinue protocol treatment for reasons other than disease progression will have tumour assessments every 6 weeks until documented disease progression. Patients may continue to receive additional cycles of therapy until progressive disease or intolerable toxicity.
Quality of Life assessment, will be measured by EORTC QLQ-C30 and QLQ-BR23 questionnaires, which will be completed by patients.
The primary endpoint for the trial is progression free survival calculated from the date of randomization until the date of progression or the date of death whatever the reason of death. The analysis of Progression-Free Survival is planned to take place when 615 progressions or deaths have been observed. One interim safety analysis is planned and will take place when 50 patients of each arm have completed at least one cycle of study treatment. It is anticipated that up to 170 active study centres will participate, and that accrual will be completed in approximately 30 months.
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|770 participants
|Intervention Model:
|Parallel Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|A Phase III Trial of Vinflunine Plus Capecitabine Versus Capecitabine Alone in Patients With Advanced Breast Cancer Previously Treated With or Resistant to an Anthracycline and Who Are Taxane Resistant.
|Study Start Date :
|May 2009
|Actual Primary Completion Date :
|December 2011
|Actual Study Completion Date :
|October 2015
Experimental: Vinflunine plus Capecitabine
Patients received (in combination with capecitabine)
• Vinflunine at the dose of 280 mg/m² and as a 20-minute IV. infusion on day 1 of each cycle repeated every 3 weeks.
Drug: Vinflunine plus Capecitabine
Vinflunine 280mg/m² as a 20-minute i.v. infusion on day 1 of each cycle repeated every 3 weeks
Capecitabine 825mg/m² per os twice per day for 14 consecutive days starting day 1 of each cycle repeated every 3 weeks
Other Names:
Active Comparator: Capecitabine single-agent
Capecitabine at the dose of 825mg/m² per os twice per day each morning and each evening for 14 consecutive days beginning on day 1 of each cycle repeated every 3 weeks (self-administered).
Drug: Capecitabine
Capecitabine 825mg/m² per os twice per day for 14 consecutive days starting day 1 of each cycle repeated every 3 weeks
Other Name: XELODA
- Progression Free Survival [ Time Frame: Baseline up to 2 years 7 months ]
PFS is defined as time from date of randomization to date of the first documentation of objective tumor progression (according to the Independent Response Review Committee (IRC) and based on RECIST version 1.1) or death due to any cause.
The PFS was primarily analysed in the Intent-to-treat (ITT) population. Patients lost to follow-up, or without a known record of progression or death at time of analysis had the progression-free survival censored at the date of last tumour assessment or the date of last contact of a follow-up showing no progression, whichever occurs last.
- Overall Survival [ Time Frame: Baseline upto 3 years 10 months ]The overall survival (OS) was defined as the duration between the date of randomisation and the date of death from any cause. The OS analysis was performed in the ITT population and the eligible and per protocol populations once the required number of events (631 deaths) was observed Patients lost to follow-up, or without a known record of death at time of analysis had the OS censored at the date of last contact.
- Overall Response Rate (ORR) [ Time Frame: Baseline upto 2 years 7 months ]ORR defined as documentation of complete or partial response that was subsequently confirmed to first documentation of disease progression or to death due to any cause, whichever occurred first.
- Disease Control Rate [ Time Frame: Baseline up to 2 years 7 months ]Disease control rate defined (DCR) as the sum of confirmed complete response, confirmed partial response and stabilisation rate.
- Duration of Response [ Time Frame: Baseline up to 2 years 7 months ]Measured from the first time that measurement criteria were first met for objective response (documented CR or PR) until recurrence/progression or death whatever the cause.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|21 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- female patients
- 21 years of age or older
- histologically/cytologically confirmed carcinoma of the breast
- documented locally recurrent or metastatic disease not amenable to curative surgery or radiotherapy
- either one, two or three prior chemotherapy regimens
- prior treatments including both an anthracycline and a taxane and patient no longer candidate for these drugs
- measurable or non-measurable disease according to RECIST 1.1
- Karnofsky performance score of at least 70 %
- adequate haematological, hepatic and renal functions
- ECG without clinically relevant abnormality
Exclusion Criteria:
- known or clinical evidence of brain metastasis or leptomeningeal involvement
- pulmonary lymphangitis or symptomatic pleural effusion
- any serious, concurrent uncontrolled medical disorder
- history of second primary malignancy
- preexisting motor/sensory peripheral neuropathy
- known history of HIV infection
- prior therapy with capecitabine and/or vinca-alkaloids
- history of severe hypersensitivity to vinca alkaloids and/or to fluoropyrimidine or contra indication to any of these drugs
- known or suspected dihydropyrimidine dehydrogenase (DPD) deficiency
- pregnancy or breast feeding
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01095003
|Study Director:
|Jean-Claude VEDOVATO
|Pierre Fabre Medicament
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|Pierre Fabre Medicament
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
2008-004171-21 ( EudraCT Number )
|First Posted:
|March 29, 2010 Key Record Dates
|Results First Posted:
|September 13, 2019
|Last Update Posted:
|September 13, 2019
|Last Verified:
|August 2019
Breast Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases
Antimetabolites, Antineoplastic
Molecular Mechanisms of Pharmacological Action
Antineoplastic Agents
Antineoplastic Agents, Phytogenic
Tubulin Modulators
Antimitotic Agents
Mitosis Modulators