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Cellulaze Treatment Northborough
Remove Cellulite Permanently – with Microsurgery!
It's Real. It Works. And it's Exclusively Here!
Introducing Cellulaze from Cynosure, the only cellulite treatment that attacks the structural problems beneath the skin that cause cellulite. A minimally invasive, laser-assisted surgical procedure performed by Board-Certified plastic surgeon Dr. Cynthia Poulos, Cellulaze is proven to destroy cellulite, improve skin tone, and melt fat for a smoother, healthier look that lasts. Dr. Poulos was recently featured in Medesthetics magazine, where she discussed the Cellulaze procedure and how well it has worked for a number of her patients!
If you're looking for cellulite treatment, Massachusetts residents trust Dr. Cynthia Poulos from Classique Medical Spa to help them look and feel their best. With minimally invasive treatments at our Northborough, MA, practice, you can get smoother looking and more attractive contours after just one session.
There are many reasons why individuals in Marlborough, MA, can have issues with cellulite. Age, hormonal changes, genetics, and profound weight loss or gain can affect the appearance of a person's legs and body. These factors cause connective tissues to stiffen, causing fat to accumulate and create creases. To help get rid of this effect, we treat our Westborough, MA, patients with a revolutionary technology called Cellulaze from Cynosure. It is the only treatment that targets the underlying structural problems that cause the look and feel of cellulite.
The way the technology works is simple. Using minimally-invasive, laser-assisted technology, Dr. Cynthia Poulos can break down large collections of fat cells to leave skin looking smoother. Only a small incision is used to allow the laser to access the targeted fat cells.
The treatment is proven to tone connective tissues and destroy excess fat cells. The laser treatment also positively affects the skin. It tightens and tones the surface of your skin. Anyone's skin can look healthier and more appealing.
Come and visit one of our offices today for cellulite treatment. Massachusetts residents will benefit from working directly with, Dr. Cynthia Poulos, a board certified plastic surgeon who has over 26 years of experience in the plastic and reconstructive surgery industries. The first step to achieving a toner looking physique is a consultation about the patient's goals and expectations. From there, we will decide whether Cellulaze is right for the patient. Contact our office today for an appointment or fill out our new patient form.


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Hands On With Sam
We're highlighting our Coles Marketing collaborators by showcasing some of their many talents. Every day they contribute ideas, designs, strategy and so much more that drives positive results for our clients.
Our copywriter, Sam Watermeier, takes words and turns them into unbelievable stories that encapsulate our clients' goals. From writing poems and creative works in his spare time to catering his writing for more technical products, Sam does it all. Below are some recent tasks he's tackled:
- Wrote copy for a new website
- Interviewed and wrote three employee spotlight articles
- Created a monthly corporate metrics report
- Helped design and write the process for crafting a newsletter template
Sam's Passions
Current Netflix Binge Show: Comedians in Cars Getting Coffee
Favorite Restaurant: Luciana's Mexican Restaurant (Arroz con pollo is the perfect meal.)
Favorite App: Bravo TV, it allows me to stream the high-seas drama of Below Deck
Describe Yourself in 3 Words: Quiet, quirky, creative
Stay tuned to see who will be featured next!Edit this post
Categories: Content Marketing | Tags: Tags: blog, Coles Marketing, copywriter, copywriting, employee spotlight, Indianapolis, marketing, sam watermeier
Five Q's with Diana Zukerman
She's a marketing guru, super stylish and extremely client savvy. Diana Zukerman is head of business development for Coles Marketing. She knows exactly what clients need to succeed. Here, we sit down with her to get the intel on her high-level expertise for 2019.
1) How do you start your day? Are you a strong coffee/hit-the-snooze-button person? Or a lemon water cleanse/yoga-up-at-5 a.m. person?
Probably more of the yoga-type person, to be honest. Every morning, it's important for me to start with a workout. Usually Pilates or the gym. So I grab my workout bag, give my sweet Bernese Mountain dog Janey a hug and head out the door. Here are a few pics of her, if you care to take a look (p.s. – She loves to go to brunch. The first photo below is her at Rosie's in Zionsville). After my workout, I reward myself with a large iced tea from Starbucks!
2) Tell us a little about your background. How have you parlayed your previous skills into this exciting role with Coles Marketing?
My background is in advertising sales for a luxury lifestyle publication. I also have been involved with several local charities on the fundraising end of things. My experiences both professionally and personally have made my role as the business development lead at Coles a perfect fit.
3) Since you're the first contact potential clients connect with, it proves just how much of a "people person" you really are! What's your favorite part about meeting potential clients?
I absolutely love meeting potential clients and learning about their roles with their companies. It's so interesting finding out what their needs are. Everyone is so different and has different goals. It's always exciting to learn about each industry. Each client is unique, and I love creating a plan of action to help them succeed!
4) When discussing a potential client's needs and wants, what are some trends you've been seeing from client to client? What kind of help are they seeking?
Everything is digital now. We see a lot of clients who want to increase their digital presence but really don't understand it. They are seeking more engagement and want help increasing the quantity and quality of traffic to their website. It's so important! We also have several clients who are looking to redo their existing website. It's essential to have a strong website. Your website is usually the first point of contact when a potential client wants to learn more about your business. You need to make a good impression.
5) Fourth quarter is coming up. And NOW is the time to start thinking about future marketing efforts! What advice can you give to someone ready to take the next step?
2018 is flying by, and it's not too late to prepare! As we approach the fourth quarter of 2018, many of our clients are reflecting on the successes of their 2018 marketing plan and how to continue to improve next year. They're turning their focus toward identifying their 2019 marketing goals and preparing their budgets for the upcoming year.
Just one meeting can make all the difference. I would love the opportunity to visit with you to review your marketing needs. Let's talk more about how Coles Marketing can provide real value to your business. Please feel free to reach out to me at firstname.lastname@example.com if you would like to set up a time to chat about your marketing needs!Edit this post
Categories: Advertising, Clients | Tags: Tags: blog, business development, Coles Marketing, diana zukerman, employee spotlight, Indianapolis
Hands On With Kevin
We're highlighting our Coles Marketing collaborators by showcasing some of their many talents. Every day they contribute ideas, designs, strategy and so much more that drives positive results for our clients.
Our Multimedia Designer, Kevin Moore, is a wizard when it comes to perfecting websites and print content. Kevin has the experience to back up his creative designs whether on paper or in the digital space. Below are some recent tasks he's tackled:
- Created and designed the user interface for three new websites
- Designed an email campaign
- Created graphics using Adobe Photoshop
- Updated Animation on client's website
Kevin's Passions
Current Netflix Binge Show: NCIS
Favorite Restaurant: City Barbeque
Favorite App: Last Day on Earth: Survival
Describe Yourself in 3 Words: Faith, Friends, Fun
Stay tuned to see who will be featured next!Edit this post
Categories: Content Marketing | Tags: Tags: blog, Coles Marketing, design, employee spotlight, Indianapolis, Kevin Moore, website design

subset: commoncrawl


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"I could barely see," says Betsy Franklin.
Betsy Franklin was legally blind in one eye when first went to visit Dr. Yichieh Shiuey.
56-year-old Franklin was legally blind in one eye due to cataracts. And, because of a large amount of astigmatism, she also had to wear thick, uncomfortable glasses.
A few days before the Christmas holiday, Franklin went to see Yichieh Shiuey, M.D., her PAMF specialist in cataract, Lasik and cornea surgery, for a post-operative visit.
Two years previously, Dr. Shiuey had performed a successful corneal transplant on Franklin. But now a worsening cataract threatened to steal Franklin's sight. "I recommended a new astigmatism-correcting lens that would permanently fix her vision as well as her cataracts," says Dr. Shiuey.
Unfortunately, the special corrective lenses are not covered under medical insurance. When Franklin learned the cost, she told her doctor that she would have to do without. Determined to provide his patient with the best option possible, Dr. Shiuey waived his operating fee and convinced Alcon, the lens manufacturer, to do the same.
"I was shocked," says Franklin.
Lens implants are regularly used in cataract surgery to restore the focusing power of the eye. Generally a 15-20 minute procedure per eye, the cloudy lens is replaced with a clear, artificial lens. But now, if the person also has an astigmatism, nearsightedness or farsightedness, using new intraocular lens implants, their vision can be corrected at the same time. These lenses are usually made of acrylic (a type of soft plastic) which is readily accepted by the body and last a lifetime.
Tiny incisions, about 2.5 millimeters long, ensure a quick recovery and most people return to their normal activities within several days. "Our success rate is really high," says Dr. Shiuey. "Over 95 percent of our patients who get these types of lenses end up with vision that is 20/40 or better, which means they can legally drive without glasses."
"My surgery took less than an hour, I was awake the whole time and there was no pain at all," says Franklin. "I can't believe the difference!" she says. "It was as if God had come and given me sight."
"Betsy cried and gave me a huge hug," Dr. Shiuey recalls. "Seeing her so happy with her new vision was my best Christmas present of all."


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This page contains freely available resources on the Liberty Protection Safeguards, contained in the Mental Capacity (Amendment) Act 2019, which are due to come into force in 2020 to replace the Deprivation of Liberty Safeguards.
The background to the Act lies in the decision of the Supreme Court in Cheshire West: for resources related to that decision and its implications, see my dedicated resource page here.
Primary legislation, regulations and other statutory materials
The Act itself can be found here. The Explanatory Notes can be found here. Links to debates and other official documents produced during its passage here. We do not yet have regulations, or the Code of Practice that will be required to before the Act can come into force, but they will be added here in due course. The Government has confirmed that it expects to lay the final draft of the Code before Parliament in Spring 2020, along with the regulations, ahead of an expected implementation date for the Act of 1 October 2020.
My overview paper with the background to and an outline of the LPS can be found here.
A good summary by Tim Spencer-Lane, who led the project at the Law Commission which led to the Bill (and to which I acted as consultant) and was then involved in the passage of the Bill itself, can be found here.
An admirably short and to the point summary by Hannah Nicholas at Hill Dickinson can be found here.
If you have a freely-available commentary that you think should be on here, please do email me, although I reserve editorial rights to determine whether to put it up. As LPS is now a-coming and debates about whether or not it is a 'good thing' are of interest but of only limited practical significance, I am primarily interested in commentary which:
(1) flags up particular issues that will have to be addressed in implementation;
(2) flags up things that can be done ahead of implementation.
Health warning
Until the regulations and the Code of Practice are published, there is still substantial flesh to be put on the bones of the legislative scheme. I strongly suggest that you are cautious about checking whether commentaries and/or training relating to the Act make clear the extent to which they contain speculation and, where they do, the basis upon which that speculation is advanced.


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Caring for your well-being remotely
The Counseling Center is modifying operations in response to COVID-19 and will continue to deliver compassionate and confidential services, educational programs, and resources. If you have questions about other campus operations in response to COVID-19, please visit the university's official site.
As of March 23, in-person counseling services will transition to 30-minute phone consultations using Microsoft Teams. Clients with existing appointments have been emailed, though if you wish to schedule a 30-minute consultation, please call (715)-232-2468.
View this guide for accessing teams and connecting with one of our counselors.
Crisis and Emergency Support
During this time if you are experiencing an emergency you should contact 911 or other mental health crisis options that are available 24/7, including:
- Northwest Connections: 1-888-552-6642 (local area)
- National Suicide Prevention Lifeline: 1-800-273-8255
- Crisis Text Line: text hello to 741741
We thank you for your flexibility as our campus navigates this complex issue. Please contact us with questions or concerns.
To transfer your care to one of our licensed and trained counselors, please have your current mental health practitioner send your treatment summary to the Counseling Center for review and processing.
An initial appointment will be scheduled to discuss care needs, answer questions about services, and complete any forms to ensure records are current. Subsequent appointments can be made following the initial appointment.


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These Garlic Mushroom Quesadillas are a quick and super tasty lunch, full of Mexican flavour. Perfect for lunch with a salad or as a starter for a Mexican fiesta!
My never ending quest for making Mexican food that rivals this little Mexican hole in the wall in San Diego that I had the BEST potato tacos brought me to making garlic mushroom quesadillas last night. Not a particularly conventional Mexican filling, but tasty none the less. Did the taste rival that of those potato tacos? Of course not. They were made in a tiny, authentic kitchen on the boarder of Mexico. They also came with free and unlimited nachos and a variety of dips and toppings and only cost $0.50 each. I was a poor backpacker, so I ate there 6 times in my 4 day stay.
If you want to be kept up to date on my new healthy and delicious recipes like this, then please subscribe to the blog mailing list (it takes 30 seconds) and you will get sent the new recipes straight to your inbox. Your email address won't be passed on to anyone and you will never be spammed. Click here to sign up
The great thing about quesadillas, and even burritos too, is that you can fill them with almost anything. I made my husband banana and chocolate spread quesadillas for dessert once and he loved them. No, I am not married to a 5 year-old, he just craves sweet things like a 5 year-old does.
How to make Garlic Mushroom Quesadillas – Serves 2:
Garlic Mushroom Quesadillas
- 4 Whole Wheat Tortilla Wraps
- 500 g Mushrooms, sliced
- 2 onions, sliced
- 4 garlic cloves, crushed
- 4 tbsp fresh coriander (cilantro) chopped
- 1 tsp chipotle flakes (optional)
- 50 g cheddar cheese
- Salsa
- Guacamole
- Heat some oil in a large pan and cook the mushrooms and onions for 10 minutes, until softened.
- Add the garlic, chipotle (if using) and coriander (cilantro) and cook for a further 3 minutes.
- Separate the mixture between 2 tortillas and spread so it covers it.
- Sprinkle the cheese over and then top with the other tortilla.
- Cook until the cheese has melted and the tortilla is golden.
- Cut each quesadilla into 4 and serve with salad, salsa and guacamole.
Nutritional Information
What is the best Mexican food you have ever eaten? Have you been to Mexico? Leave a comment to make me jealous of how amazing the food was!


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Do you feel a bit UGH!
There are many time in your life that you are going to feel low. There are going to be lots of up and downs that you need to work through. You hit a point where you know you need to change something to make yourselves feel better. It might be changing your diet, starting a new exercise routine, working towards some great new life-changing goals. Sometimes though you need a boast to get yourself motivated.
Making Goals & Keeping Track
Writing the goals down or what you are eating in your journal will help you keep track of your progress. You will also benefit from having some supportive motivational quotes within those journal pages to help keep your head in the right place as you work through the mental uphill struggle to where you want to be.
You can find these great 10 Motivational Quotes in the Little Craft Mouse Resource Library as free downloadable pdf that you can print and stick into your journal.
What is Bullet Journaling?
You can find out more about journaling, How to Bullet Journal and other great Bullet Journal tips here – www.thelittlecraftmouse.co.uk/how-to-bullet-journal/


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Riverwest tattoo artist shows off work to national audience
A Milwaukee artist is showcasing his work to a national audience.
Garrett Bisbee is featured on the current season of "Ink Master" on the Paramount Network, formerly Spike TV.
"Ink Master" is a reality show that is in its 10th season, and Bisbee is one of the contestants. The show pits tattoo artists from all over the country against each other to see who is the most talented.
"The tattooing community, especially out here in Milwaukee, is super great," said Bisbee. "Everyone is so supportive of each other."
Bisbee said the producers of the show contacted him.
"They were, like, 'Hey, we saw you on Instagram. We really like your work.'"
The 23-year-old is this season's youngest cast member.
"Some guys that were on the show have been tattooing longer than I have been alive," he said.
Bisbee works at Riverwest Tattoo Co. on Center Street. He got his first tattoo when he was 18 and realized he might have some talent.
"(I thought) 'I can draw as well as these guys. Why can't I do this?'" Bisbee said.
Now he's inked up from head to toe.
"I have my whole front torso, my back tattooed, both legs, both arms, my neck," Bisbee said.
But don't ask him how tattoos he has.
"I have absolutely no idea. I have a lot of works in progress." he said.
Bisbee's most noticeable tattoo is a cicada on his face.
"I used to catch cicadas all the time with my little brother when we lived in Japan," he said. "I just thought they were super cool bugs and I have a pretty large insect collection at home."
Bisbee has been tattooing professionally for almost four years now. He said he's mostly self-taught and has never taken a formal art class.
Bisbee spent three weeks in New York City shooting "Ink Master." He was eliminated last week in the second episode.
"One of the hardest things I have ever done," he said, "but I got to make a lot of friends."
The show might be over for Bisbee, but his passion for art and creativity must go on.
"I just like the freedom of it really," Bisbee said of his chosen profession. "I'm my own boss."


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We produce windows and doors carpentry against individual orders and client's requirements.
On the basis of our long experience, we offer 3 wide ranges of wooden doors and windows: period wooden sash windows, wooden casement windows, and tilt-turn windows. If you need exterior wooden doors to match our wooden replacement windows, we provided popular timber sliding folding doors, wooden front doors, and stylish wooden French doors.
Copyright © 2020 Wima Windows - Window Service. Company Registration Number 8478539, VAT Registration Number: 161960404
Web Design by Local Business Ranking


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Born from a passion for cycling and honed by a vision to design exquisitely crafted carbon fibre and aluminium bikes, Orro is a British manufacturer whose models scream quality, performance, innovation and style.
Whilst each of these core principles is equally important as the next, it's innovation that really sets Orro bikes apart. Orro work with renowned British composite experts in order to manufacture unique, high-performance frames. Indeed, every bike carries the Orro Shape Design (OSD) logo as a sign of its quality.
Orro's home in the Sussex downs, an area of outstanding natural beauty, provides both the design inspiration and the perfect testing ground for new models. As a nod to the evolving trend of road, gravel and adventure bikes the majority of Orro bikes use disc brakes for better, more controlled stopping power. Scroll to look at Orro bikes in more detail…
Terra G
First up, it's the Orro Terra Gravel. A lightweight, aluminium-framed road model with a smattering of gravel bike features. Thru axles front and rear, a low bottom bracket and clearance for 35mm tyres – all features that help when you lead the bike away from tarmac.
The Shimano 105 version with hydraulic disc brakes will make the perfect entry level gravel bike, or a dependable winter bike if you're a committed, all-season road rider.
Terra C
Stepping up from the Terra Gravel, you'll find the Orro Terra C – a high quality carbon-fibre adventure bike. The frame includes Innegra impact protection, a material used in the layup of the carbon which helps the bike cope with the impacts of a rough and tumble gravel ride.
The 105 version, with hydraulic brakes, tubeless ready wheels and 42mm tyre clearance looks like a winner!
After something racier? Look at the Orro Venturi, a specially designed aero disc road bike. The Venturi is manufactured using a special carbon fibre from UK composite wizards Sigmatex. This results in a lower frame weight, whilst maintaining ride stiffness and comfort. Other things to note are the Venturi's flat mount disc brakes, thru axles front and rear, aero seat post and tubeless compatible wheels.
Pyro Evo Disc
Moving away from adventure bikes and into a pure road model: the Orro Pyro Evo Disc. This is Orro's road endurance platform - a carbon bike designed for big miles on tarmac. All the endurance bike characteristics are present and correct: oversize downtube for power transfer, slender seatstays and 28mm tyre clearance to absorb torrid road conditions, internal cable routing for excellent shifting performance and disc brakes to bring you to an assured stop.
Carbon Technology
Great Britain is a renowned leader in composite technology with companies deploying their expertise in fields such as Formula1 and the aerospace industry. Orro have capitalised on this, collaborating with the carbon fibre producer Sigmatex in the development of their all new Gold STC and STC Signature carbon fibre bike models. The Innegra impact protection material used in the Terra C, again from Sigmatex, is a further demonstration of Orro's commitment to innovative use of composite materials in their bikes


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Smarten Up Painting is a QLD registered business with ASIC ABN 16411838548 Primary Contractor License No is 169637C QBCC No is 15068687. There has been 0 complaints about the company since trading began in the year 2000, all our subcontractors carry a police check (provided on request). Smarten Up Painting is insured with Allianz for workers comp and carry a public liability cover for $20,000,000. As members of MPA the company has extensive access to staff, equipment hire and other resources. In 18yrs within the industry we have built valuable relationships with other reputable companies in Sydney and Brisbane and often combine recourses on larger projects
Looking forward to meeting you,


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Cassie and Wiz collab to shoot their new music video off her new RockAByeBaby mixtape. The music video was shot in the streets of LA. Go and download her new mixtape now.
Cassie and Wiz collab to shoot their new music video off her new RockAByeBaby mixtape. The music video was shot in the streets of LA. Go and download her new mixtape now.
Tagged cassie, khalifa, music, official, Paradise, video, wiz
Juelz Santana releases the official music video for "Everything Is Good" featuring Wiz Khalifa & Bucksy Luciano.
Tagged Bucksy, everything, good\, is, juelz, khalifa, Luciano, music, official, santana, video, wiz
Currensy releases his "New Jet City" mixtape which features his own artists off the Jets, Jadakiss, Rick Ross, Wiz Khalifa, Juicy J, Juvenile, French Montana and Trinidad James. Here is a track off the tape called "Clear".
Here is the new single from Curren$y ft. Wiz Khalifa and Rick Ross called "Choosin" off Currensy's "New Jet City". Look out for new projects from all camps.
Watch Snoop and Wiz in the studio recording some tracks. Follow Wiz Khalifa @RealWizKhalifa and Snoop Dogg @SnoopDogg.
Tyga releases a new track called "Molly" ft. Wiz Khalifa & Mally Mall. New video most likely coming soon.
Wiz Khalifa gives you another episode of his "Day Today" series. Shows him performing, getting interviewed and doing crazy shit as usual. Check out Celebrity Sole to see what kicks Wiz is wearing today.
Posted in Sneakers
Tagged day, day today, episode 5, khalifa, season 4, today, wiz, wiz khalifa
Posted in Sneakers
Tagged big sean, drake, joe budden, khalifa, mike posner, wiz
Wiz Khalifa freestyles over a rock-type beat while in his tour bus. It also shows footage of die hard fans trying to run to the vehicle he is in. Peep the video below.


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SANTA FE SPRINGS – The thrills will last an extra three minutes at the city's Fourth of July fireworks show next week.
Santa Fe Springs officials have expanded their annual show by three minutes, and they are adding a giant slide to the extravaganza. The event begins with a horseshoes tournament at 8a.m. Tuesday at Los Nietos Park, 11143 Charlesworth Road, said Ana Alvarez, community services director.
There will be many family activities throughout the day, including train rides, face-painting, arts-and-crafts workshops and a watermelon-eating contest from 1 to 4 p.m. The fireworks show begins at 8:45 p.m. Admission to the day's activities is free.
"This is one of those times when the community comes together, and we have a family gathering," Alvarez said.
Elsewhere in the area, fireworks shows are scheduled in Pico Rivera, La Mirada and La Habra.
La Mirada is hosting its free family fair a day early. The celebration, from 4:30 to 8:30p.m. Monday at La Mirada Regional County Park, 13701 S. Adelfa Ave., will feature old-fashioned picnic games and live entertainment. Fireworks begin at 9 p.m.
La Habra's annual celebration begins at 5 p.m. Tuesday in the football stadium of La Habra High School, 801 W. Highlander Ave. There will be games for children and other family activities during the day, followed by fireworks at 9:15 p.m.
Tickets are $5 for adults, $2for children, but you can buy tickets in advance at $3 for adults and $1 for children today and Saturday only at the La Habra Community Center, 101 W. La Habra Blvd.
The Pico Rivera fireworks show, for the first time in several years, will be at Smith Park, 6016 Rosemead Blvd. The show is free. It begins at 9 p.m. Tuesday
"We wanted to bring it back to give people an opportunity to sit down, bring blankets and get them to relax," said Cecilia Arellano, who works in Pico Rivera's public information office.
La Habra Heights, Montebello and Whittier are not holding fireworks shows. Located in brushy hillsides, La Habra Heights has never held a fireworks display.
Montebello and Whittier canceled their shows in recent years due to a lack of funds. Montebello City Administrator Richard Torres said because of ongoing renovation work at Grant Rea Park, the city again can't afford a fireworks show this year.
(562) 698-0955, Ext. 3024


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This Sleek New Balance MS997 Is a Tokyo Design Studio Creation
Brand: New Balance Tokyo Design Studio
Model: MS997
Key Features: The juxtaposition of the sleek, minimalist upper with the new color-blocked, chunky sole gives this sneaker two defining features and makes the wearer feel they are rocking a hybrid sneaker of sorts.
Release Date: February 9
Price: $150
Buy: New Balance
Editor's Notes: A mainstay in New Balance's lineup, the 997 is one of the brand's most recognizable silhouettes. Nevertheless, it seems the company has decided it was time to give the 997 a 2019 update, and so here is the New Balance MS997, available in two colorways.
It has been officially announced that the MS997 is a Tokyo Design Studio creation.. Tokyo Design Studio sees the brand's American and Japanese design teams come together to create innovative products that utlize skillful craftsmanship unique to Japan.
The new shoe stays true to its chunky soled soul, but is given a modern twist with color-blocked layers of green, blue, yellow, purple, and pink in addition to the white sole.
On the other hand, the new MS997 upper is a complete departure from the original, with its minimal black or light grey leather and suede upper.
To stay updated on everything happening in the sneaker world, follow @Highsnobietysneakers on Instagram, check our sneaker release date calendar and subscribe to our sneaker chatbot on Facebook to receive lightning quick updates to your inbox.
Our designated shopping section features products that we love and want to share with you. Highsnobiety has affiliate marketing partnerships, which means we may receive a commission from your purchase.


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Amanda Bird
Associate Professor
347 C Campbell Hall
1787 Neil Avenue
Columbus, OH
Areas of Expertise
- Transcriptional Regulation
- Nutrient Homeostasis
Research in the Bird lab focuses on metal ion homeostasis in eukaryotic cells. Metal ions including zinc, copper, iron, and manganese, are required for the function of approximately one third of all proteins and one half of all enzymes. Although we know much about the function of a given metal within a protein, we know relatively little about the processes by which cells maintain sufficient levels of 'available' metal ions for incorporation into newly synthesized proteins. As too much or too little of any metal is detrimental to human health, the long-term goals of our research are to determine how cells maintain optimal levels of labile metal ions for incorporation into folding polypeptides, and how proteins obtain their correct metal cofactors in vivo. To gain insight into these universal processes we use the fission yeast Schizosaccharomyces pombe as a model system to study how cells maintain optimal levels of zinc within the cytosol and organelles. We also investigate how metallo-enzymes within the secretory pathway preferentially bind to correct metal cofactors. As the regulation of metal ions is universal to all cells, our research will provide insight into how metal ion homeostasis and metal ion selectivity is regulated in higher eukaryotes.
Choi S, Hu Y-M, Corkins ME, Palmer AE, and Bird AJ (2018) Zinc transporters belonging to the Cation Diffusion Facilitator (CDF) family have complementary roles in transporting zinc out of the cytosol. PLOS Genetics (in press)
Bird AJ and Labbé S (2017) The Zap1 transcriptional activator negatively regulates translation of the RTC4 mRNA through the use of alternative 5' transcript leaders. Mol. Microbiol 106:673-677.
Corkins ME, Wilson S, Cocuron JC, Alonso AP, and Bird AJ (2017) The gluconate shunt is an alternative route for directing glucose into the pentose phosphate pathway in fission yeast. J Biol Chem 292:13823-13832
Wilson S and Bird AJ (2016) Zinc sensing and regulation in yeast model systems. Arch Biochem and Biophys. 611:30-36
Bird AJ (2015) Cellular sensing and transport of metal ions: implications in micronutrient homeostasis. J. Nutr. Biochem. 26:1103-1115
Ehrensberger KM, Corkins ME, Choi S, and Bird AJ (2014) The Double Zinc Finger Domain and Adjacent Accessory Domain from the Transcription Factor Loss of Zinc Sensing 1 (Loz1) Are Necessary for DNA Binding and Zinc Sensing". J Biol Chem. 289:18087-18096
Choi S, and Bird AJ (2014) Zinc'ing sensibly: controlling zinc homeostasis at the transcriptional level. Metallomics 6:1198-1215
Corkins ME, May M, Ehrensberger KM, Hu YM, Liu YH, Bloor SD, Jenkins B, Runge KW, Bird AJ (2013) Zinc finger protein Loz1 is required for zinc-responsive regulation of gene expression in fission yeast. Proc Natl Acad Sci USA 103:8674-79.
Ehrensberger KE, Mason C, Corkins, ME, Anderson C, Dutrow N, Cairns B, Dalley B, Milash B, and Bird AJ (2013) Zinc-dependent regulation of the adh1 antisense transcript in fission yeast. J Biol Chem. 288:759-769
Ehrensberger KE and Bird AJ (2011) Hammering out details: Regulating metal levels in eukaryotes. TIBS 36:524-31
Frey AG, Bird AJ, Blankman E, Evans-Galea M, Winge DR, and Eide DJ (2011) Zinc-regulated DNA Binding of the yeast Zap1 zinc-responsive activator. PLOS One 6:e22535
Wu CY, Roje S, Sandoval FJ, Bird AJ, Winge DR, and Eide DJ (2009) Repression of sulfate zinc assimilation is an adaptive response of yeast to the oxidative stress of deficiency. J Biol Chem 284:27544-56
Wu CY, Bird AJ, Chung LM, Newton MA, Winge DR, and Eide DJ (2008) Differential control of Zap1-regulated genes in response to zinc deficiency in Saccharomyces cerevisiae. BMC Genomics 9:370-387
Khalimonchuk O, Bird AJ, and Winge DR (2007) Evidence for a pro-oxidant intermediate in the assembly of cytochrome oxidase. J Biol Chem 282:17442-9
Bird AJ (2007) Metallosensors, the ups and downs of gene regulation. Adv Microb Physiol 53:232-57
Bird AJ, Gordon M, Eide DJ, and Winge DR (2006) Repression of ADH1 and ADH3 gene expression during zinc deficiency by Zap1-induced intergenic RNA transcripts. EMBO J 25:5726-34
Wu CY, Bird AJ, Winge DR, and Eide DJ (2006) Regulation of the yeast Tsa1 peroxiredoxin by Zap1 is an adaptive response to the oxidative stress of zinc deficiency. J Biol Chem 282:2184-95
Bird AJ, Swierczek S, Qiao W, Eide DJ, and Winge DR (2006) Zinc metalloregulation of the zinc finger pair domain. J Biol Chem 281:25326-35
Qiao W, Mooney M, Bird AJ, Winge DR, and Eide DJ (2006) Zinc binding to a regulatory zinc-sensing domain monitored in vivo by using FRET. Proc Natl Acad Sci USA 103:8674-79
Keller G, Bird AJ, and Winge DR (2005) Independent Metalloregulation of Ace1 and Mac1 in Saccharomyces cerevisiae. Eukaryot cell 4:1863-71
Herbig A, Bird AJ, McCall K, Mooney M, Chang-Yi W, Eide DJ, and Winge DR (2005) Zap1 activation domain I and its role in controlling gene expression in response to cellular zinc status. Mol Microbiology 57:834-46
Bird AJ, Blankman E, Stillman DJ, Eide DJ, and Winge DR (2004) The Zap1 transcriptional activator also acts as a rpressor by binding downstream of the TATA box in ZRT2. EMBO J 23:1123-1132
Rutherford JC and AJ Bird (2004) Metal-responsive transcription factors that regulate iron, zinc and copper homeostasis in eukaryotic cells. Eukaryot Cell 3:1-13
Bird AJ, McCall K, Kramer M, Blankman E, Winge DR, and Eide DJ (2003) Zinc fingers act as Zn2+ sensors for regulation of activation domain function in the yeast Zap1 transcriptional activator. EMBO J 22:1-10
Evans-Galea M, Blankman E, Myszka D, Bird AJ, Eide DJ, and Winge DR (2002) Two of the five zinc fingers in the Zn-regulated Zap1 transcription factor dominate site-specific DNA binding. Biochemistry 42:1053-1061
Bird AJ, Zhao H, Luo H, Jenson LT, Srinivasan C, Evans-Galea M, Winge DR, and Eide DJ (2000) A dual role for zinc fingers in both DNA binding and zinc sensing by the Zap1 transcriptional activator. EMBO J 19:1-10.
Bird AJ, Evans-Galea M, Blankman E, Zhao H, Luo H, Winge DR, and Eide DJ (2000) Mapping the DNA binding domain of the Zap1 zinc-responsive transcriptional activator. J Biol Chem 275:16160-16166
Bird AJ, Turner-Cavet JS, Lakey JH, and Robinson NJ (1997) A carboxyl-terminal Cys2/His2-type zinc finger motif in DNA primase influences DNA content in Synechococcus PCC 7942. J Biol Chem 273:21246-21252


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You're at work and into the room walks your least favorite co-worker -- the one who always thinks he's right. He has an answer for everything and seems to have an air of superiority about him, as if he thinks that it should be a privilege to breathe the same air as he does. Figure out ways to deal with a person who says he is never wrong without resorting to storming away or buying a voodoo doll.
He Secretly Feels Inferior
Perhaps he actually lacks information and instead of being okay with the gaps in his knowledge, he overcompensates by claiming that he is always right. Accordingly, he may secretly lack the confidence to accept his weaknesses. People like this are often extremely sensitive to rejection. Although he comes across as Mr. Know-It-All, his ego is probably more fragile than it appears.
Respond Carelessly
If you don't have a lot of time or energy to deal with his shenanigans, you can opt for taking the path of least resistance. Just nod your way out of the situation. This is one of the easiest and most commonly used escape routes for dealing with people who think they're always right. This gives him the impression that you agree despite your real feelings. You can also give him a closed-ended response, such as "Hm. That's interesting," and then move on.
Manage Your Irritation
If the person who thinks he's right all the time is in your family, focus on managing your reactions to him. If you yell at him and say "You think you're never wrong!" you will probably make him defensive; he may conclude that you are overreacting. Instead, notice when you start to get irritated and then make an effort to either end the conversation or steer it in a different direction.
Have Compassion for Him
Since he probably secretly lacks confidence, try to empathize with him. In all likelihood, he is not trying to irritate you. He is just trying to show you that he's intelligent, suggests the 2002 article "Narcissism, Self-Esteem, and the Positivity of Self-Views: Two Portraits of Self-Love" by W. Keith Campbell, Eric A. Rudich, and Constantine Sedikides in the "Personality and Social Psychology Bulletin." Instead of rolling your eyes, try listening to what he has to say. If he makes a valid point, don't hesitate to acknowledge this.


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There are times when ft seems that fish have a sixth sense, especially when a net is put into the aquarium! In fact, they analyze the situation with their lateral line and their sense of smell and in this way they deduce whether there is a possibility of danger. This premonition of a danger or a particular event seems to be heightened in those fish that are normally the most friendly. It is therefore perhaps better to talk of hypersensitivity in these species.
The position of the mouth can similarly reveal eating habits:
• a mouth in the upper position indicates a top-feeder;
• a mouth in the terminal position is the sign of a fish that hunts underwater;
• a mouth in the lower position indicates a bottom-feeder.
Water is aspirated through the fish's mouth, passes through the branchiae and is expelled due to the movements of the operculum, which covers them. There is always some water washing the branchiae of the fish. Oxygen requirements are not directly proportional to the size of the fish, with the smallest species being the greatest consumers of oxygen: ten fish weighing 1 g each consume more oxygen per gram of body weight than one fish of 10 g.
The barbels
Fish that live on the bed or in dark environments (colored or turbid water) have barbels around the mouth (Corfdoras, Botia, for example).
These appendages have a tactile and sensory role. By complementing or replacing the eyes, they enable the fish to detect possible sources of nutrition.
The nostrils
Two or four in number, these are located in front of the eyes. They play no part in respiration but, extended inside the head by an olfactory sac, they perceive and analyze smells.
This protects the branchiae and guarantees the circulation of water through the regular movements of the valve, ensuring that the branchiae are always in contact with the water from which they extract oxygen. The term "gills".
• The mouth of this marine fish (Forcipiger flavissimus, the yellow longnose butterfly) allows it to capture its prey in the crevices of thecoral.
Theglass silurid detects its food partly as a result of its barbels. •
• The blind tetra (Anoptichthys jordani) does not have any eyes but detects its prey and enemies with its lateral line.
sometimes incorrectly used, refers to the opening produced by the movements of the operculum, which serves as an exit for the water that has irrigated the branchiae.
Running symmetrically along each side of the fish's body, the lateral line is more or less visible, according to the species. It consists of a succession of pores that communicate with a canal situated under the skin. This important organ does not exist in any other vertebrates. While the senses of taste and smell, highly developed in fish, allow them to recognize a greater number of smells than humans, at very low concentrations, the lateral line, with its special cells, detects and analyzes the vibrations of the water and sends this information to the brain. In this way a fish can be aware of the proximity of an enemy, of a prey... or of the approach of the aquarist (see box, p. 47). The importance of the lateral line is apparent in the blind tetra (Anoptichthys jordani), which never bumps into an obstacle even though it has no eyes.
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'Redmond' is a popular surname in this part of Ireland. The Norman knight, Raymond Le Gros is the original 'Redmond' in Ireland. There are historical references to Raymond's descendants living in 'Redmond Hall' on this site in the 16th century.
To find Loftus Hall…
Type these coordinates into Google: 52.146166, -6.907399
To the West along the Way lies… Slade Harbour
To the East along the Way lies… Baginbun Beach
Hook Head Adventures
Hook Head Adventures
Let the Normans lead the way…


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Posted on 27/10/2015 by admin | 0 comments
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DURHAM Phyllis Eileen Vuolo, 82 years old, passed away on December 1, 2018. Born in Fair Lawn, New Jersey, she attended Rutgers University and was a member of Rainbow Girls and a lifetime member of Order of Eastern Star, Southgate Chapter #177 in Durham, North Carolina. She was employed with Avon Cosmetic Corporation in New York and was a manager of Systems Answering Services. She was employed as a New Jersey Certified Dental X-Ray and side-chair dental assistant with Schwartz Dentistry Associates in Westwood, New Jersey. She had an associate degree in Interior Decorating and was a certified Diet Control Center lecturer. She was an avid bowler and a pro-football buff.
Phyllis is survived by her son, Kenneth Kreger Vuolo and wife Debbie of North Carolina and two grandsons, Austin C. and Jamison P. of North Carolina. She is predeceased by her husband, Matt Vuolo and brother, Thomas Conrad Kreger or Hawthorne, New Jersey.
In lieu of flowers, please make donations to Duke Homecare and Hospice, 4321 Medical Park Dr. # 101, Durham, NC 27704.
The Vuolo family is under the care of Hall-Wynne Funeral Service, Durham, NC. For online condolences, please visit www.hallwynne.com; select obits.


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Fall 2004
Contact Information:
Instructor: Michael T. Brannick, Ph.D.
Office: PCD 4121
Mail Box: PCD 4118 G
Fax: (813) 974-4617
Voice Mail: (813) 974-0478
Course Information:
Class meets: PCD 2124
Lecture: M, 9:00 – 11:50 a.m.
Office Hours: W 2:00 – 3:00 PM
Appointments available by request
Brannick, M. T., & Levine, E. L. (2002). Job Analysis. Thousand Oaks, CA: Sage.
Upon successful completion of the course, you will be familiar with several kinds of job analysis, including the units of work, the types of descriptors, and the methods of analysis. You should be able to choose a type of job analysis best suited for answering specific questions of interest to you and to an organization. You should be able to go into an organization and be confident of doing a solid job analysis for their needed purpose(s). You should also have some idea of the current literature on job analysis and current issues worthy of research.
Grades will be based on your job analysis projects and class presentation and discussion. Final grades are based on a percentage of total points (80-89 percent = B, 90+ =A, etc.).
Project 1: Interview and task inventory development.
This assignment will give you initial experience in job analysis. You choose a job to analyze. The job must be one that you have not held, so that you are not already familiar with its contents. Get permission to study the job from appropriate authorities. Then
(1) Look up the job in O*NET
(2) Interview at least one incumbent and one supervisor of the job.
(3) Observe at least one incumbent performing at least part of the job.
(a) a narrative (one paragraph) job description
(b) a list of tasks suitable for a task inventory (10 to 100 tasks)
(c) a description of the process of analyzing the job (1 to 2 pages documenting what you did)
Prepare a formal paper (about 5 pages, tops). You will present the paper orally in class. Use some kind of visual aid in your preparation (e.g., handout, overhead, powerpoint, etc.). Be sure to share your job description and some or all of your task statements. The idea is a round table discussion of what you learned, what difficulties you encountered, etc., that will be useful to you and others in subsequent job analyses. You don't have to administer a task inventory, just develop the task list.
Point total: 100
Project 2: Job Analysis for Selection.
The second project is to give you experience in doing job analysis in an organization for personnel selection. You may work in groups of size 1 to 3. You need to (a) find an organization and job (b) conduct a job analysis, and (c) recommend one or more tests to the class (a copy can go to the organization, but is not required). You do not need to actually buy or construct a test. Rather, you need to identify the KSAOs needed for the job and to identify or create ways to measure them. You should consider effectiveness, efficiency and fairness in your choice of tests and measures.
(a) a narrative (one paragraph) job description
(b) a list of KSAOs and their links to the tasks/job activities
(c) a list of tests/assessments, the rationale for their choice, and a description of their acquisition/development.
Prepare a formal paper (about 5 to 10 pages, tops). You will present the paper orally in class. Use some kind of visual aid in your preparation (e.g., handout, overhead, powerpoint, etc.). Be sure to share your job description, development of KSAOs, and justification for the type of test you plan to use. The idea is a round table discussion of what you learned, what difficulties you encountered, etc., that will be useful to you and others in subsequent job analyses. You don't have to administer tests, just develop measurement ideas linked to the KSAOs.
Point total: 150
Class presentation and discussion.
I expect you to read the assigned material prior to attending class. I will spend some time lecturing to introduce a topic or to add some fine points. We will discuss material assigned for that day. We will apply some of the techniques we are learning about during class period in more of a workshop format than a lecture and discussion format. Please be alert and constructive during these activities. For each article or chapter, please write one question or comment (can by anything) and bring it to class along with a copy to turn in to me. These will help form the basis for some of the class discussions.
Point total: 50
· Recording of class notes for purpose of sale is forbidden.
· See me if you need special accommodation for any aspect of this class.
· Religious observances: Notify me in writing by the second class period if you will miss class due to major religious holidays. Please provide me with a list of dates of classes you will miss and the name(s) of the holiday(s) observed.
Course Calendar
Aug 23
B & L, Chapter 1
Aug 30
Work Oriented Methods
B & L, Chapter 2; Christal & Weissmuller; Flanagan; Manson, Levine & Brannick
Sep 3
Labor Day Holiday
Sep 13
Worker Oriented Methods
B & L, Chapter 3; McCormick & Jeanneret; Shippmann et al (2000).
Sep 20
Doing a Job Analysis study
B & L, Chapter 9; Dierdorff & Wilson; Voskuijl & van Sliedregt
Sep 27
Hybrid Methods
B & L, Chapter 4; Prien, Prien & Gamble; Maurer & Tross; Sackett & Laczo
Oct 4
Project 1 due
Oct 11
Management & Teams
B & L, Chapter 5; Morrison, Payne & Wall
Joan Brannick visit 10:00 a.m.
Oct 18
Legal Aspects
B & L, Chapter 6; Spector, Jex & Chen; Tross & Maurer; Wilson
Oct 25
Job description & performance appraisal
B & L, Chapter 7; Borman, Campbell & Pulakos
11. Nov 1
Compensation, Design
B & L, Chapter 7; Kochhar & Armstrong; Morgeson & Campion (2002); Campion & Thayer
12. Nov 8
B & L, Chapter 8; Robertson & Smith; Allworth & Hesketh; Gutenberg et al.; Jeanneret & Strong
13. Nov 15
B & L, Chapter 8; McKillip; Jones, Sanchez, et al.; Tett & Burnett
14. Nov 22
Project 2 reports
15. Nov 29
Future trends
B & L Chapter 10; Harvey & Wilson; Sanchez & Levine; Morgeson & Campion (2000)
References (required readings)
1. Allworth, E., & Hesketh, B. (2000). Job requirements biodata as a predictor of performance in customer service roles. International Journal of Selection and Assessment, 8, 137-147.
2. Borman, W. C., Campbell, C. H., & Pulakos, E. D. (2001). Analyzing jobs for performance measurement. In J. P. Campbell & D. J. Knapp (Eds.) Exploring the limits in personnel selection and classification (pp. 157-180). Mahwah, NJ: Erlbaum.
3. Campion, M. A., & Thayer, P. W. (1985). Development and field evaluation of an interdisciplinary measure of job design. Journal of Applied Psychology, 70, 29‑43.
4. Christal, R. E., & Weissmuller, J. J. (1988). Job-task inventory analysis. In S. Gael (Ed.) The job analysis handbook for business, industry and government (Vol. 2) pp. 1036-1050. New York: Wiley.
5. Dierdorff, E. C., & Wilson, M. A. (2003). A meta-analysis of job analysis reliability. Journal of Applied Psychology, 88, 635-646.
6. Flanagan, J. C. (1954). The critical incident technique. Psychological Bulletin, 51, 327‑358.
7. Gutenberg, R. L., Arvey, R. D., Osburn H. G., Jeanneret, P. R. (1983). Moderating effects of decision-making/information processing job dimensions on test validities. Journal of Applied Psychology, 68, 602-608.
8. Harvey, R. J., & Wilson, M. A. (2000). Yes Virginia, there is an objective reality in job analysis. Journal of Organizational Behavior, 21, 829-854.
9. Jeanneret, P. R., & Strong, M. H. (2003). Linking O*Net job analysis information to job requirement predictors: An O*Net application. Personnel Psychology, 56, 465-492.
10. Jones, R. G., Sanchez, J. I., Parameswaran, G., Phelps, J., Shoptaugh, C., Willimans, M. White, S. (2001). Selection or training? A two-fold test of the validity of job-analytic ratings of trainability. Journal of Business and Psychology, 15, 363-389.
11. Kochhar, D. S., & Armstrong, T. J. (1988). Designing jobs for handicapped employees. In S. Gael (Ed.) The job analysis handbook for business, industry and government (Vol. 1) pp. 288-302. New York: Wiley.
12. Manson, T. M., Levine, E. L., & Brannick, M. T. (2000). The construct validity of task inventory ratings: A multitrait-multimethod analysis. Human Performance, 13, 1-22.
13. Maurer, T. J., & Tross, S. A. (2000). SME committee vs. field job analysis ratings: Convergence, cautions, and a call. Journal of Business and Psychology, 14, 489-499.
14. McCormick, E. J., Jeanneret, P. R. (1988). Position analysis questionnaire (PAQ). In S. Gael (Ed.) The job analysis handbook for business, industry and government (Vol. 2) pp. 825-842. New York: Wiley.
15. McKillip, J. (2001). Case studies in job analysis and training evaluation. International Journal of Training and Development, 5, 283-289.
16. Morgeson, F. P., & Campion, M. A. (2000). Accuracy in job analysis: toward an inference-based model. Journal of Organizational Behavior, 21, 819-827.
17. Morgeson, F. P., & Campion, M. A. (2002). Minimizing tradeoffs when redesigning work: Evidence from a longitudinal quasi-experiment. Personnel Psychology, 55, 589-612.
18. Morrison, D., Payne, R. L., Wall, T. D. (2003). Is job a viable unit of analysis? A multilevel analysis of demand-control-support models. Journal of Occupational Health Psychology, 8, 209-219.
19. Prien, E. P., Prien, K. O., & Gamble, L. G. (2004). Perspectives on nonconventional job analysis methodologies. Journal of Business and Psychology, 18, 337-348.
20. Robertson, I. T., & Smith, M. (2001). Personnel selection. Journal of Occupational and Organizational Psychology, 74, 441-472.
21. Sackett, P. R., & Laczo, R. M. (2003). Job and work analysis. In W. C. Borman and D. R. Ilgen (Eds.) Handbook of Psychology: Industrial and Organizational Psychology, Vol. 12 (pp. 21-37). New York: Wiley.
22. Sanchez, J. I., & Levine, E. L. (2000). Accuracy or consequential validity: which is the better standard for job analysis data? Journal of Organizational Behavior, 21, 809-818.
23. Shippmann, J. S., Ash, R. A., Battista, M., Carr, L., Eyde, L. D., Hesketh, B., Kehoe, J., Pearlman, K., Prien, E. P., & Sanchez, J. I. (2000). The practice of competency modeling. Personnel Psychology, 53, 703-740.
24. Spector, P. E., Jex, S. M., & Chen, P. Y. (1995). Relations of incumbent affect-related personality traits with incumbent and objective measures of characteristics of jobs. Journal of Organizational Behavior, 16, 59-65.
25. Tett, R. P., & Burnett, D. D. (2003). A personality trait-based interactionist model of job performance. Journal of Applied Psychology, 88, 500-517.
26. Tross, S.A. , & Maurer, T. J. (2000). The relationship between SME job experience and job analysis ratings: Findings with and without statistical control. Journal of Business and Psychology, 15, 97-110.
27. Voskuijl, O. F. & van Sliedregt, T. (2002). Determinants of interrater reliability of job analysis: A meta-analysis. European Journal of Psychological Assessment, 18, 52-62.
28. Wilson, Mark. A. (1997). The validity of task coverage ratings by incumbents and supervisors: Bad news. Journal of Business and Psychology, 12, 85-95.


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By JB Sanders
Is it hot yet? I can't tell…
Higgs-Bosun Explained
Confused as to what the Higgs-Boson is all about? Here's a handy animation explaining everything. More or less.
The "British Atlantis" Found
So really what they mean is some underwater archaeologists have found remains of the civilization that existed on the land bridge between Britain and Europe 6500 years ago. Which is still really cool.
Light-Speed Baseballs
What would happen if you tried to hit a ball traveling at 90% the speed of light?
Self-Destructing Poem by William Gibson
More than 20 years ago, William Gibson helped create a poem called "Agrippa (a book of the dead)", and it was included on a floppy disk (along with some art). After you viewed the poem, the contents of the disk, including the poem itself, were scrambled and unreadable. Now a PhD student is working on the problem, and before he could even work on the disk, he: compiled a disk image of the floppy, a System 7 emulator (Mac OS 7, that is), and most of the source code of the application which displays the poem. Now he's sharing it online and offering a copy of every book Gibson wrote (NOT including the Agrippa poem) if you can figure out how Gibson did it. You have to show your work!
Movie Posters As If They'd Been Done 1000 Years Ago
You know, Medieval.
Warning: these will seriously warp your brain in amusing and baroque ways.
A Lamp Grown From Salt
Interesting idea in making new light fixtures.
Behind-the-Scenes Photos from Godzilla 1954-65
Because nothing gets your geek juices flowing like Godzilla pics. I'll reserve the comments about guys in rubber suits.
Star Wars Figures Do the Movies
I know that sounds redundant, but in this case it's Star Wars minis posed and shot mimicking famous pictures or movie posters.
Trojan Power Strip
It's a power strip that hides a small computer inside, designed to "test" network vulnerability. Basically, you walk this thing into a company, plug stuff into it, and hack away.
Minecraft and 3D Printing
What's not to like? It's a six-minute video on the post-scarcity economy. And it's way cooler than that makes it sound.
LEGO™ Robots and Wargaming
You probably already clicked on the link, but here's the deal: it's a slew of pictures of LEGO™ robots, which are being used to play a war-game. Anyone can play, they just need LEGO ™ robots.
Here are the rules:
About John:
John's a geek from way back. He's been floating between various computer-related jobs for years, until he settled into doing tech support in higher ed. Now he rules the Macs on campus with an iron hand (really, it's on his desk).
Geek Credentials:
RPG: Blue box D&D, lead minis, been to GenCon in Milwaukee.
Computer: TRS-80 Color Computer, Amiga 1000, UNIX system w/reel-to-reel backup tape
Card games: bought Magic cards at GenCon in 1993
Science: Met Phil Plait, got time on a mainframe for astronomy project in 1983
His Blog: http://glenandtyler.blogspot.com


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NOKEN Test Preparation
The NOKEN exam, called after the Japanese initials (Nihongo Nouryoku Shiken, 日本語能力試 験) or JLPT if we use the English initials (Japanese Language Proficiency Test), is an official exam internationally recognized which goal is to certify the level of Japanese for non-native students. It is organized by the Japan Foundation outside the country, in Japan the responsibility is of the JEES (Japan Educational Exchanges and Services). It currently consists of five levels: N5, N4, N3, N2 and N1; N5 being the lowest level and N1 the highest one. You can only choose one level every time you take the exam, but you are free to choose which one.
This means you don't have to take any kind of test before the exam, you can choose the level you want.
There are five places where you can take this exam in Spain:
Madrid (Universidad Autónoma de Madrid – CEAO & Universidad Complutense de Madrid (UCM) – Idiomas Complutense)
Barcelona (Universidad Autónoma de Barcelona – Facultad de Traducción e Interpretación)
Santiago de Compostela (Universidad de Santiago de Compostela – Centro de Lenguas Moderna)
Granada (Universidad de Granada – Centro de Lenguas Modernas)


text: I couldn't be more pleased with the copyediting job being done for the book I'm currently working on. I got the first couple of chapters back today, so that I could make sure it was being done at an appropriate level and give the copyeditor some feedback. My job is going to be a lot easier when this comes back thanks to having someone who is both an excellent copyeditor and has a good grasp of technical things. Is it weird that having something copyedited so well makes me extremely happy?


text:
Throughout the autumn, stop by any service desk and let us know when you walk, ride, or share your way to the Library. We have car magnets and stickers to reward your efforts. Help us spread the word to walk, ride, and share your way to the Library.
Preview parking before your next trip to the Library.
There are 130 spaces in the Library parking lot, and additional spots in the Elmhurst Art Museum parking lot. Other parking options are available nearby. Obey all posted signs.
BLUE: this is the Library's parking lot. Parking in this lot is for Library users only-All others will be ticketed. Additional spaces are available in the Elmhurst Art Museum lot when the Library lot is full. (these spaces have no time limit)
GREEN: free parking anytime the Library is open (these spaces have a maximum of three hours) EXCEPTION: The parking structure on Adelaide St. is available for $2 for all day parking, or free after 5 p.m. on weekdays and all day on weekends.
YELLOW: free parking after 5 p.m. on weekdays and all day on weekends (these spaces have a maximum of three hours)
RED: This is the Library Staff lot. Parking in this lot (on the corner of Park & Prospect) is permitted after 5:30 p.m.
PURPLE: drop off/short term parking. Picking up a child? Returning a book? Use the drop off lane to run in to quickly return materials or grab a hold, and don't forget about the Outside Book Drop and Drive-Up Window!
Our mailing address is: 125 S Prospect Ave Elmhurst, IL 60126
Public Transit:
Metra Union Pacific West Line: Schedule
Pace Bus 309 Pace Bus 332 Pace Buse 645 Pace Bus 643


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Friday, December 1, 2017 - Sunday, January 7, 2018
Packed with family fun, Fifth Third Bank Winter WonderFest at Navy Pier is a beloved annual Chicago winter event, featuring 170,000 square feet of carnival rides, giant slides, holiday-themed activities, and Indoor Ice Skating Rink, and more. Experience the city's biggest and best indoor winter playground and join the millions of families who have made it a part of their annual holiday tradition!
Learn more at navypier.org/winter-wonderfest.
Planning to attend this event? Getting to Navy Pier has never been easier. Learn more about our convenient transportation and parking options.


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Great waterfront plot in the boaters paradise of GOLDEN ISLES. 4 bedroom, 3 bathroom one-story home lovingly cared for. NO FIXED BRIDGES, DIRECT OCEAN ACCESS, 93 FEET OF WATERFRONT, 20 FOOT WOODEN DOCK WITH BOAT LIFT WITH 2 DAVITS, UNDERWATER LIGHTING ON SEAWALL. Added benefit of a den which could be a 5th bedroom. Spacious backyard with 2000 sq ft patio and large pool adjoining the water. GOURMET CHEF'S kitchen, bonus room for maids quarters, studio, etc.. (w/ private entrance). Garage fits either 2 cars or 1 with maids room/studio. Benefits from 2 tankless water heaters. Proximity to stores, beach and I-95 (R).
This listing is courtesy of FIP Realty Services, LLC.
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The data relating to real estate for sale/lease on this web site come in part from a cooperative data exchange program of the multiple listing service (MLS) in which this real estate firm (Broker) participates. The properties displayed may not be all of the properties in the MLS's database, or all of the properties listed with Brokers participating in the cooperative data exchange program. Properties listed by Brokers other than this Broker are marked with either the listing Broker's logo or name or the MLS name or a logo provided by the MLS. Detailed information about such properties includes the name of the listing Brokers. Information provided is thought to be reliable but is not guaranteed to be accurate; you are advised to verify facts that are important to you. No warranties, expressed or implied, are provided for the data herein, or for their use or interpretation by the user. The Florida Association of Realtors and its cooperating MLSs do not create, control or review the property data displayed herein and take no responsibility for the content of such records. Federal law prohibits discrimination on the basis of race, color, religion, sex, handicap, familial status or national origin in the sale, rental or financing of housing. This property is courtesy of FIP Realty Services, LLC.
* (Based on a 30-year fixed rate of 6.25% with 10% down.)


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Aries woman has a charm that is like Leo. Just like Leo's woman she is an independent, courageous and creative woman. But there are some things from Aries women that you should know. Here are some things you should avoid when dealing with women Aries.
1. Brave woman
Aries women are women who are confident, optimistic and have high courage. She also feels that she is the most independent woman, and she is not afraid of any threats. She is very capable to take care of herself. See also Ways to Win an Argument with an Aries Easily
2. Very irritable
Her dominant attitude makes her being a good leader in the work environment, or in her love affair. However, you should be knowing that Aries women are very irritable. So do not comment negatively about her.
3. Good at faking
She is very good at faking. Visible from the outside the Aries woman looks strong, but deep in her heart, she is a very fragile figure.
4. Vengeful woman
Immediately apologize if you hurt her. She is a difficult woman to forgive others. Her memory of your mistakes will continue to be remembered and she will not forgive you.
5. Loving freedom
Aries woman loves freedom, she tends to do what she wants. If you curb it, of course, she will give a stabbing comment and she will rebel on you. See also Aries Woman Traits Love to Know
6. Say goodbye to the drama
A woman who is indifferent, in her life there is no word "drama". "A drama is only in the movie", said Aries women. If you act like a queen drama, of course, she will leave you without thinking.
7. Honest
For Aries women telling the truth is important. She is not a hypocritical and inconsistent woman. She prefers to tell the truth in front of you rather than gossiping behind.
8. A selfish woman
She has a dominant attitude, so it is making Aries woman becomes selfish. She does not really care about other people. She preferred to be in her own world.
The signs that Aries woman has the same heart as you
Do you wonder if the Aries woman who you like also has the same heart as you? Below here are the signs that Aries woman has the same heart as you. Absolutely, she is very interested in you.
1. Learn about your hobbies
Aries woman will try to find out about you and she will learn what your interests have been. They are very enthusiastic, is it right? That is because she is interested in you. See also How to Make an Aries and Capricorn Relationship Work
2. Shows a cheerful face
Who is not cheerful if she is in love? Seeing this cheerful Aries woman makes you even more charmed, right?
3. Excited
Aries women always excited in every time, either in their work and being with you. Congrats you are the person that special to her.
4. She wants to be your closest friend
Aries women are friendly, kind, and honest. It is no wonder she has many friends. Among her friends, she seems to want you being her close friend. So, go on.
5. What do you say she will listen to
She will be willing to stay with you all day for listening to all of your stories. Whatever your problem she will always be there beside you, and she will provide the best solution for you. See also Best Ways to Get an Aries Man
6. Often staring at your face
Try occasionally to pretend not to see her, but it turns out she looks occasionally often staring at your face. She seems to want you the only person in her heart.
7. She really cares about you
If an Aries woman is already interested in one person, she will start to notice. Usually, she uses this way, she reminds the person to never forget to rest and eat. Oh, it is so sweet.
How to tell if an Aries woman doesn't like you
Are the signal of her does not match with your expectations? Maybe you made a mistake on her. Remember, she is prone to anger. Does she show the signal as below? Below here is how the Aries woman declares that she does not like you. So, let's check these out.
1. Never glance at you
How to tell if an Aries woman doesn't like you? Take a look, when you turn around and you will return home, whether she has a chance to glance at or see you? If not, then she is not interested in you. It looks like you have to try hard to get her heart.
2. Just act casually
You have prepared everything to make her interested in you. However, what happened? Her attitude is like not interested in you and she is acting very cold towards you. See also Signs an Aries Man Has a Crush on You
3. She has many reasons
You already have tickets to watch the concert on weekends. However, luck is not on your side. She refused you because she had another appointment.
4. No impression at all
When she is having dinner with you, she's so cool. She only answers your questions briefly. Dinner with her really no impression at all.
5. She is being indifferent
A woman if they are interested in a man she will definitely try to make up, change her hairstyle and even buy new clothes to looks impressive. But unfortunately, the Aries woman whom you like did not do that.
6. Do nothing
There is not a single sweet sentence is out in her lips, it is just loud and piercing words only. It is a signal that means she does not like you. See also Best Ways to Make an Aries Man Fall in Love
7. Think of you as an enemy
Aries woman who has been hurt, she will not be able to forgive the person. She will always remember your mistakes and she even thinks of you as her enemy.
8. She lies
She is lying because she thinks you are not someone she is interested in. That is why she dared to lie in front of you.
9. Her face looks sour
There was no cheerful face on Aries woman. When she confronted someone who upset her and was annoying, she will make face like that.
10. She is not showing interest
There are no signs that show any interest in you. Maybe it's time to give up. It's obvious she does not like you. See also How to Tell If A Leo Woman Is Interested in You. That's how to tell if an Aries woman doesn't like you!
Hopefully, the review of how to tell if an Aries woman does not like you it can give you an answer about her. Does she have the same heart as you or not? Do you know, women Aries really like men that are honest, loyal, and smart like her. For that, keep trying to get the heart of an Aries woman. Good luck.


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An introduction to Vue.js – Part 2: How to develop components with Vue.js
This is the second part of our article series "An introduction to Vue.js". For the first part click here >>
Whether you are fortunate enough to start a whole new project or have to face the even more exciting challenge of continuing an existing and grown project – there are always decisions to be made, especially at the beginning. A not-so-insignificant decision is how to equip your toolbox.
The programming language should already be set in most cases, but there are still some imposing questions: How do I write my source code? More importantly, how do I organize it? How do I translate my technical requirements into clean, preferably high-quality and well maintainable source code that developers can survey and understand with ease? Frameworks help us in this context. Vue.js [1] is such a framework and a very versatile and universal one at that.
Why use Vue.js?
There is also the pleasant side effect that you can test your applications even easier with Vue.js, because everything in there is pure JavaScript. With test frameworks like Mocha [2] or Jest [3], almost everything can be tested efficiently without trouble. What's more, because Vue.js is based on core technologies like HTML, CSS, and JavaScript, it can be easily integrated into existing projects. In this way, small individual components can be isolated and are brought under the control of Vue.js. The framework can be introduced step by step. Vue.js can also be useful for fast prototyping, for example, when you need to have something up and running at short notice to be able to quickly get feedback from the future user of the application.
In addition to its excellent performance, there are other soft factors which speak in favor of this framework. For example, the documentation that is available on the website of Vue.js quite helpful. It's often said that open source projects have poor documentation or even none at all. This is by no means true for Vue.js. The functioning community should not remain unmentioned. Developers in the Vue.js community are always friendly and understanding. Questions are also usually answered in a quick, uncomplicated, and decent manner.
Everything put together
The term component is derived from the Latin verb componere and it means compounding [4]. Houses are a good example of component orientation outside of IT. For example:
Within the context of civil engineering, a hole must be dug for the basement component, whereby the basement does also consists of its own components – such as floor slabs, white tubs and the ceiling. The ground floor component is located in the basement, followed by the upper floor and roof. Each of these individual components is made up of its own components. For each of these components, there are specialists who plan, implement, and maintain them. Civil engineers, masons, cleaners, electricians, and carpenters – everyone is a specialist and a master craftsman in their field.
Another good comparison shows quite clearly how the results can look if you think that you can do everything on your own in Figure 1: The attempt of a student of the Royal College of Arts in London. Unfortunately, the topic of component- orientation is still too rarely taken seriously in software development today. It is also unfortunate that many developers think they have to be particularly creative and reinvent the wheel over and over again. Cut it out. The good news is that modern web application frameworks such as React, Angular, or Vue.js not only support us to think more component-orientated at this point, but rather that they force us to so.
Components in Vue.js: No reusability at all costs
The component concept of Vue.js aims to create easily maintainable and reusable units of code. But reusability does not mean reuse at all costs. It is rather a question of dividing a functional requirement, for example an application for entering classified ads, into small components. The aim is to provide a better overview of these small component modules. The application is divided into a hierarchical structure of software modules of which it is composed piece by piece.
Of course, it does make sense to reuse one of these modules in a different context if needed. However, it should not be the developer's claim to develop reusability and generic routines at all costs. Therein lies the danger that we create our own problems by unconsciously bringing complexity into the project. To be honest, it is also no problem if the code is kept redundant in one place or another. A carpenter doesn't use just one saw during construction; they use saws specifically tailored to their needs. Redundancy is not bad per se; if it does serve a better understanding of the software architecture, then it is most certainly no mistake.
The first component
If you look at a typical web application, you will usually find a display in the upper right corner showing which user is currently logged in. This can be achieved through a component, a module that can be reused in other parts of the application. The form for recording the classified ads, in the core a <form>, can be the next component. Other components of the form such as a date selection can also be implemented as child components, which are used by the classified ad entry component (the so-called parent component).
Actually, the components are grouped HTML. However, if a component consisted only of HTML, the whole thing would be a boring and static matter. Through CSS and JavaScript, components are glammed up and become dynamic. Frameworks such as React, Angular, and Vue.js offer us the possibility to unite all of these parts into components in its own specific way. In the case of Vue.js, it is meant quite literally. Components allow you to add new tags to HTML (custom tags). In this way the log-in component becomes a <login> tag and the entire classified ad entry form can suddenly be used with a simple tag, like .
Listing 1 shows how easy it is to create components in Vue.js. Through the static component method, the component is registered to the Vue.js object. Basically, Vue.js components, like Vue.js instances, are defined as a JavaScript array with name-value pairs. Thus, the hello-world-component in listing 1 is registered under the name hello-world. The HTML fragment is defined in the template option, which is to be output when using the <hello-world> tag. You may be wondering now why the component was not called hello or helloWorld; if that is the case, then please refer to the official Vue.js style guide [5]. Since there is no real convention on how to name custom HTML tags, here's a few valuable tips. You should avoid using single words to evade potential name conflicts. Apart from the fact that it is highly unlikely that there will ever be a <hello> tag in the HTML standard, the probability there will be a <hello-world> tag is close to zero.
According to the style guide, the use of Camel Case is definitely allowed. However, in practice it has been shown that a Camel-Case-like component name such as HelloWorld does not work right away in the Chrome browser and that it is interpreted as helloworld. This leads to mistakes. Therefore, multi-wording separated by hyphens is recommended here.
Listing 1: The first Vue.js component

 <hello-world />

Globally registered Vue.js components, such as in Listing 1, can be used anywhere in the application, even if individual components are subject to the control of different Vue.js instances. Of course, components can also be bound to individual Vue.js instances by logging on to the desired Vue.js instance with the components option. Listing 2 depicts an example. The solution, which is presented in the listing, is to define the component as a constant in advance. This is certainly the more sensible approach for registering the components with other Vuw.js instances later if required. However, it is also possible to make the registry directly at the components option.
It is important to understand that components are reusable Vue.js instances. Therefore, Vue.js components share many properties with Vue.js instances. Options like data, computed, watch, or even methods can be used for components, just as you are used to with normal Vue.js instances. The event model exists analogously for components. There are no more specific options, such as el, for binding a Vue.js instance to a specific HTML tag. This is not surprising as components themselves become HTML tags. The number selection component is deliberately used multiple times in Listing 2. An attentive reader will quickly realize that here each component instance is able to manage its own state. This is made possible by defining a function instead of the data in the data option – in contrast to Vue.js instances.
Theoretically, it would be conceivable that a developer, instead of this (correct) code
data: function() { return { count: 0 } }
writes the following (wrong) variant:
data: { count: 0 }
Regardless, as Vue.js would not accept and execute the simplified variant at all, it should be clear that this cannot work for potentially multiple instances of the component.
Listing 2: To bind a component directly to a Vue.js instance and use it multiple times

 <select-number initial='100' suffix='EUR'> </select-number> <select-number> </select-number> <select-number initial='200' suffix='SFR'> </select-number>

From top to bottom
An important concept of Vue.js components is their unique selling proposition. Components should be able to stand for themselves and have as few interrelationships and relationships as possible with other higher-level components. Those who stick to this concept will end up with a modular system where applications can be simply plugged together. Moreover, you are rewarded with small, easily manageable software blocks that are easier to maintain. The topic of testability should not remain unmentioned here; this is because small, self-contained, and isolated software units can be covered much easier (and faster) with unit tests.
Another basic principle in Vue.js components is that data may only ever be passed down. Interdependence should not occur, because the programming model of Vue.js provides only one way: from top to bottom. To pass data down, the option props is offered, which stands for properties. Here, you can pass either an array of string objects or a collection of objects. Listing 2 shows an example. The commented-out props demonstrates the variant with the string array and the values after the initial and suffix – the actual data is passed in the form of properties on the component tag – arrive in the component. The second props variant allows for more explicit specifications. In Vue.js, this feature is called Props Validation. Among other things, you can also define which type of data is expected (String, Number, Boolean, Functions, Objects) and whether a property must be obligatorily committed (required). The default values can also be defined here.
With the second <select-number> component in Listing 2, neither an initial nor a suffix value is passed. The counter starts with the value 10 in this component instance, but an error is displayed in the console. This indicates that the suffix is a required field for which no value has been passed.
The typical Java developer will now ask themselves how they can explicitly access the data or the state of a particular component instance, if the data can only be passed from top to bottom. Normally, you would iterate through the list of available components and call a getter.
That is exactly what you are not supposed to do in Vue.js. Passing data from parent to child simply means that the data is held and managed in the topmost, if not even in the root component. Individual data components are pressed downwards, so changes to the data records thus automatically remain at the very top of the data source.
Custom events and references
Hopefully, for the rare cases in which a child component has to pass on information upwards, you can fall back on a special event handling: the custom events. Here, the child component triggers an event and notifies its parent. To do this, the parent component must be bound to an event using the v-on directive. You must also specify which JavaScript function is to be called when this event occurs. In the child component, you can use the $emit function provided by Vue.js to trigger an event. It is here, where the event name and data are to be transferred. The superordinate component listens in on this event, is notified, and receives the data. This principle of passing from top to bottom is good style in Vue.js applications and should not be broken.
For those hopefully even rarer cases where there is no other way around it and you have to access internals of child components, Vue.js also offers the possibility of working with references. In practice, this means that you set the ref property for each component you want to access and assign a unique name to the component. In the superordinate component, the $refs function gives you the chance to get a list of all components marked with ref. This way, you can easily reach into individual components.
Single file components
For a Vue.js developer, it is important to shape the source code of an application in such a way that it can be further developed in the future without any obstacles. Components are an important tool in this context. If all components, as it is the case in Listing 2, are distributed directly to one HTML file or to several JavaScript files, then the source code may still be too compressed. If you intend to change your component B later, then you will still be bothered by the source code of the components A and C, which can lead to unnecessary context switches and distracted developers.
So, in order to make a clear cut in the level of data, each component could be led into its own JavaScript file. This would undoubtedly work, however, the problem remains – only pure JavaScript can be used. HTML or CSS component parts must be packed in string.
Vue.js ventures in a similar direction with its single file components, but it is based on a completely different concept. The basic idea is to keep all components of the component as legible as possible in one file. The individual components are therefore separated by special tags. The HTML part is stored within two <template> tags, the JavaScript code is in the


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School Group Reservations
Reservations for Theater for Youth School Performances (School Groups Only, Please) Call 713-524-9196 or email firstname.lastname@example.com
To Book a School Matinee!
To make an introductory inquiry please complete the online form below and we will contact you within 48 hours to discuss your request, or contact Martha Oviedo at 713-524-9196 x 1025. All required fields are indicated with an asterisk *.
Please remember that children under the age of 3, including sleeping babies, are not allowed in the theater.
School Group Ticket Prices
School Performances: $7.00
Title 1 Schools receive a $0.50 off of the above listed price.


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Read Mrs. Strong's latest message.
Students in grades 1-5 will be taking the MAP (Measures of Academic Progress) assessment this Fall. Please click to view dates and times for each grade level's testing.
Online Registration Information
Beginning this school year, you will see changes in the Learning Behaviors section of the HCPSS report card.
2019-2020 JHES School Supply List
2018-2019 Volunteer-- Confidentiality Training Course
JHES- Please join the PTA
Supporting a Student's Mental Health
HCPSS Connect
Access your student's information and classroom instructional tools
Student access to Canvas, Google Apps, Office 265, & MackinVIA
Student Handbook
Guidebook for expected student behaviour
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Reporting incidences of bullying
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Get an overview of the HCPSS curriculum
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Academic Advisory Committees
Discuss district-wide curriculum initiatives
Howard County Association of Student Councils
Take part in a county-level student organization


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– If sperm gets damaged DNA in the final stages of maturation , may affect sperm quality. They are less able to fertilize an egg and give rise to a living child . Fertilization with sperm with damaged DNA can lead to early abortion because the fertilized egg does not develop normally and therefore banished says researcher Ann -Karin Olsen at the Division of Environmental Medicine , Institute of Public Health.
Increased likelihood of disease in offspring
– Can be damaged spermatozoa cause disease in the next generation?
– We believe that such damage may lead to increased risk of disease , but there is a difference in the effect of the damage to germ cells , and the damage to " semi-mature " and nearly mature sperm get. Damage to the stem cells are the most serious of these are mutations which will also be found in all cells of the offspring , says Olsen.
– When it comes to damage to the " semi-mature " and nearly mature cells , we know that such sperm can fertilize an egg even though they have much damage. But fertility is reduced , and the further development of the fertilized egg ( embryo ) is disrupted . To what extent such damage on disease development in the offspring , we have less knowledge , continue Olsen.
Olsen adds that research results can not be directly transferred to humans because the experiments conducted in mice, and it is used high levels of benzo ( a) pyrene , much higher levels than we humans are exposed to daily. The knowledge about the mechanisms that are most important. However, research results are consistent with other observations . For those couples who use IVF to have children see , for example, that men who smoke are less likely to become a father than non- smokers.
Studies show a correlation between paternal smoking and the risk of certain cancers in children .
Do not wait too long with kids – Do men who smoke damaged sperm forever?
– We must distinguish between damage to the stem cells and damage to sperm cells during development. If the stem cells have been DNA mutations , any sperm that develop from these cells carry the mutations . Injuries sustained in the final weeks before conception are not mutations , they will primarily provide poor semen quality and thereby reduce the likelihood of having children.
– Can we do anything to prevent injuries , besides being a non-smoker ? – I would recommend that you generally avoid harmful chemicals wherever possible . It is shown that other drugs may damage the sperm in the same manner as benzo (a ) pyrene . For men who are planning to father I would say that it is wise to consider what you expose yourself to before conception. It takes about three months from a stem cell begins to divide until it has given rise to mature sperm. In addition , I think it is wise that men do not wait too long to have children. The genetic changes accumulate during a long life , says Olsen.
Norwegian and Danish men have poorer sperm quality than men from Finland , Sweden and the Baltics. The researchers speculate that this is because women started smoking earlier in Norway and Denmark than in the other countries. There is now evidence that women's smoking during pregnancy are important for the development of the testes in male fetuses and their future semen quality .
Further research
The research project at the Institute of Public Health continues with several investigations. The researchers will examine what happens when low doses of ia benzo ( a) pyrene used for extended periods , which are more relevant to the way we humans are exposed to these substances. Other hazardous substances are interesting to examine.
– We want to identify the bad guys – the substances that are dangerous for the male gametes , says Olsen."
While none of those 4,000-plus chemicals is good for your baby (you would never add a dollop of lead and cyanide to his strained peaches), two compounds are especially harmful: nicotine and carbon monoxide. These two toxins account for almost every smoking-related complication in pregnancy.
The most serious complications — including stillbirth, premature delivery, and low birth weight — can be chalked up to the fact that nicotine and carbon monoxide work together to reduce your baby's supply of oxygen. Nicotine chokes off oxygen by narrowing blood vessels throughout your body, including the ones in the umbilical cord. It's a little like forcing your baby to breathe through a narrow straw. To make matters worse, the red blood cells that carry oxygen start to pick up molecules of carbon monoxide instead. Suddenly, that narrow straw doesn't even hold as much oxygen as it should.
A shortage of oxygen can have devastating effects on your baby's growth and development. On average, smoking during pregnancy doubles the chances that a baby will be born too early or weigh less than 5 1/2 pounds at birth. Smoking also more than doubles the risk of stillbirth.
Every cigarette you smoke increases the risks to your pregnancy.
Weight and size, Body and lungs, Heart and Brain function is Object for being affected by smoke.
Undersize babies tend to have underdeveloped bodies. Their lungs may not be ready to work on their own, which means they may spend their first days or weeks attached to a respirator. After they're breathing on their own (or even if they did from the start), these babies may have continuing breathing problems — because of delayed lung development or other adverse effects of nicotine. Children whose mothers smoked during pregnancy are especially vulnerable to asthma, and have double or even triple the risk of sudden infant death syndrome (SIDS). Babies whose mother smoked or being around smoke in the first trimester of pregnancy are more likely to have a heart defect at birth. Smoking during pregnancy can have lifelong effects on your baby's brain. Children of pregnant smokers are especially likely to have learning disorders, behavioral problems, and relatively low IQs. "
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