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Every time I come here, I feel like they put me after a really great presentation and then you see my title and you're like wah-wah. Because I'm always talking about something that's kind of, how do we process things in a way that might be a bit better and make things more efficient, or something operational. I tend to take on those topics a lot. So I really want to thank TJ for his presentation this morning because it really brought back to mind for me, what is the main thing that got me involved. About seven or eight years ago, I said to other people at Optum, we ought to allow companies to have these libraries. They said, well why, and I said, well it takes time to go through these reviews and a lot of times they're using the same programming and it just makes sense. And you know, you think about it from an efficiency standpoint, but the more important thing is the patient standpoint, because the longer it takes to get a trial into the field, the longer it takes to get data and get treatments that are of value out to patients. So thanks to him for that, and hopefully that tidbit will help keep people interested and say, this isn't really just administrative, there are really very important outcomes to patients, based on how we go about doing things.
Two other things to start with. One is yes, I work for Optum, I work in the Patient Insights Division. That used to be QualityMetric, before we were bought. I work as a scientist, so my main interest is understanding patients and how they feel and function and what it's like to live with diseases and their treatments. So while there is a licensing group, and I'm here talking a bit about how that group interacts, I'm actually coming from the science perspective on it a little bit. And the third thing is, just because my mind wanders a lot, I was thinking, how did I come up with this "library" word in the first place? Because really, everybody kind of keeps libraries or inventories of all sorts of things, right. Everybody has a file folder in their computer systems, and it's not really anything relatively new, so you might be thinking, why do you have to have a process for this, we all keep and reuse things over and over again. And you know, what I hope you come away from this with is an understanding of why it's important to have a sort of relationship about how you do it, with the instrument developer, whomever that is. As a scientist I work with lots of different instrument developers. And I chose library as opposed to inventory because inventory just sounds like one small person in this really big warehouse and eventually in a movie someone comes by with a forklift and chases them and there's lots of blood and it's a bad thing, whereas I grew up going to a library and you have a librarian and it's very warm and somebody's answering questions for you and there's back and forth. That's how I really want to see this, this is a relationship between eCOA vendors and study sponsors and instrument developers.
So for context here, some of these terms you're going to know. Any instrument, any type of clinical outcome assessment may be available for licensed use in several different modes. You could get it on paper, and you might program it in a device to look exactly like it does on the paper version. You may use a single item form. In Optum we call that a SIF. And there's two different versions that we have. One is for a large tablet, seven-inch or above, a larger diagonal or computer screen. And the other would be for a smartphone or a small screen.
Many instrument developers require form reviews of the eCOA programming prior to use, and that is to ensure proper migration. The positives of this: ensures the users program the correct version and mode correctly. And that can help ensure good implementation and interpretation of data. And I could tell you that there have been times when someone has forgotten to send form reviews and we've reviewed it and it's been a significant problem. Like a repeat of a response choice, in which data was collected that had to then not be used. So it is an important thing to do.
There are some negatives to this process that include an impact on your study timeline, because it takes some time to get them reviewed. If not everything's right, then you have to correct it and send it back again and it gets reviewed again. There's a cost to the study sponsor to have this done, because it takes someone's time to review it. And you know, there is this issue of sometimes having to repeat reviews for the same instrument, even for a same sponsor that's for a different study.
So my goal today is really to describe and answer questions about our own Optum Patient Insight eCOA library program. I can't speak on behalf of all similar programs. But we started doing this many years ago just for eCOA companies, and now we recognize the need for study sponsors to really understand what's going on. So it's a little bit different approach.
There are some definitions I'm going to use today. Some of these you may know. An eCOA, here for this presentation, is any clinical outcome assessment presented in any kind of electronic format. SIF, I'm going to say that, and that just refers to a single item form presentation of any instrument, as opposed to having many questions on a paper at once. Sponsor is any company funding a study that will use an eCOA. It could or could not be a pharmaceutical company, but in this audience I'm going to assume that it is a pharmaceutical company. I'm going to say eCOA vendor as opposed to eCOA company, because this presentation is a little more targeted for the study sponsor today. But it could be any company, whether it's specifically an eCOA company or a larger company that just has a component that does that, or even a pharmaceutical company that has its own department and solution for that. Library, here we're talking about a collection of approved eCOA programmed instruments. And they're approved based on a form review of screenshots. And then a license is an agreement between an instrument developer or authorized distributor and sponsor, to use an instrument for a specific purpose.
I have to go through a little more boring stuff, sorry. I'm going to use the example of the SF-36v2. Traditionally, what a study sponsor does in order to use it is to get a license. And then the eCOA vendor fills out a separate form called the Acknowledgement by Agent, or ABA. And that allows them to use, receive, and program the SF-36v2 for just that study. Upon the execution of those, the study sponsor is the one who receives the correct forms, and they should be responsible for providing that to the eCOA vendor. And they receive three different forms. One is the instructions on how to correctly format it, and that only comes in English. Then, for each language and country, a Word document table that's non-formatted that includes text strings that you could just copy and paste into programming, and then also a screenshot example. So in a non-library approach, you conduct form reviews for every single instrument in every single language and country for every study.
What is our form review process? After programming and the eCOA vendor's own QC process, the eCOA vendor submits screenshots to this email address. Our science teams are the ones who conduct the review to identify errors and send back a review form that specifies any errors to be corrected. And the process is iterative, it goes until there's no errors. The final form review has to be marked as "passed review." And that's approved for use for just that study.
Why would we not just let anyone reuse prior programming? Well our primary goal here is to ensure the highest quality standards for our COAs and eCOAs. And the incorrect reproduction of them can impact study findings and the resulting publications. And that can really be catastrophic for patients, healthcare providers, sponsors, and us. It's really important, and we've gone back and looked at data before and found issues where items got reversed and then the scoring software worked incorrectly, and things have been missed. And that's really important to not have it happen. We also know that eCOA companies or vendors also want the highest quality reproductions. They don't want to have any problems with what they're doing. And they want to be apprised also of any updates to instruments. We try to not update instruments as much as possible, but some countries change their entire language sometimes and there's things that you have to do, or change a different grammatical aspect.
In the past, most devices were programmed specifically for every study and it was a little less feasible for eCOA vendors to maintain a library that's more official. But now, different approaches make it more feasible.
The solution that we're talking about today is this library partnership program, and it's something that we've done for five years now, directly with vendors. But this year we started offering it to sponsors. I think, when we've worked with vendors, it gets a little difficult because they're really trying to get every study underway, and this was a thing that just relied on them and us, and there was no sponsor involvement, so it's really hard to get it going and have someone paying attention to it. So in this case what we're doing is having a master licensing agreement for a library for the sponsor, which includes review of every instrument form until it's passed to be able to enter the library. Once you have an MLA in place (the master license agreement), you have individual statements of work that just define usage for the study but you don't have to go back through and do the form review again.
There is a pricing for it, but it varies depending on the number of forms and languages that you would want. And then the base package identifies only one eCOA vendor of choice, but you could expand it to work with multiple vendors, because we know that some companies work with more than one. It's renewable annually, and the fee is reduced after year one. But I think it's important to know that the fees do not include any fees that your eCOA vendor might charge to actually program these and maintain it.
I went through that kind of fast. So I said it was a partnership. So for the eCOA vendor side of it, the partner requirements that are in place is to submit a policy. It doesn't have to be official SOP—because I know companies don't like to give those out—but it at least has to be something that you put in writing that says, this is how we're going to maintain this library, this is how we're going to make sure that there's a process for checking the code in and checking the code out, and so that there won't be changes to it. Now that I've been doing this for quite some time, some people have probably also experienced this, that a programmer may say, oh I like this word better, and they change it and they put it back in and you check it, and you say, why is this changed, you guys did this many times before and it never was different. Oh, Jim over here in Ohio thought it would be a good idea and read better. And you'd be surprised at how often that happens. So you'd want to have these check-in and check-out procedures. You'd want to know who's the point of contact for us. And we'd want to know any QC processes that would govern the library, including review for drift, so occasionally checking. You'd have to maintain an itemized list of the contents for each sponsor library, that specifies the approved instruments by name, form type, and language. And the reason we want the eCOA vendor to do this is because every so often we want to match that up with what we have and what we think you have in the library. And then participating in a recheck process, and I didn't specify out too much what that was here, but generally it involves about every few months, hopefully if there's a study upcoming that requires those languages but otherwise randomly selected, rechecking several forms. Meaning, we often do that and tell you yes, these are still okay, clearly your processes are working.
What do we need to think about? I just went through a lot of stuff kind of fast. For a sponsor, I think some of the questions—but I want to hear from you, I really want to hear what would make this work better for you. For a study sponsor, I think you'd need to think about: Which instruments does my company use? Which vendors does my company use? If I were to enter into a library program, how would I inform my colleagues or other internal stakeholders? Maybe you're in an HEOR or PRO group within the company and you want to make sure that medical affairs knows, that different clinical departments know. Even education groups or whatever else, that they have this opportunity to use this on an ongoing basis. So how would you inform them, and how would you keep that relationship going internally. And then, who would communicate with Optum and the vendors to keep that list going of the updated library contents and understand what the new study needs might be if they change or something isn't included.
For a vendor, I think the questions that you might have are: How will I maintain library content separately for different sponsors, or is this even required. So far, with different sponsors we've talked about, there has not been an interest in a combined library. But what we did before directly with vendors was not sponsor specific. Anyone could access it once it was in the library, and we're not opposed to it at all. But we understand that study sponsors may want—they might have their own logos that they want to put on things, or other things like that they don't want to share, or their own look and feel. So I think the vendors have to think about how they would be able to maintain those separately. And what is the best way to maintain the library contents and communicate with Optum?
And then, this one to me, this last one, is really important for vendors: How will I construct the library ahead of a need for a study. Because at least in my experience with eCOA companies is that you get a study contracted, you know what provisioned device or BYOD or whatever that you're going to use is, and then you get the intellectual property and you start programming it and you go through QC processes. But in order to have a library, the idea is that you would program all of these ahead of time so that they would be ready when the sponsor needed them. There's a couple different ways to do it. You could also build a library by saying once they're in there, we keep it in there but we're not going to build it in advance. But I think if the sponsor enters into this and says, hey we want to do this partnership and we want you to do that, you need to think about, well how am I going to do that, or what would I charge the sponsor to build this in advance so it would be ready for them.
So that's something, and just to put it in context a little bit, the SF-36v2 standard, which is the four-week recall alone, we have over 180 translations, and each one of those is a form. And acute has just as many. Then you've got the SF-12 and many other forms. So we're not talking a small amount of programming and list keeping and storage.
So those are some things that I think about when I think about how can we make this work, how can we build a partnership, and do this in a way that is going to help studies get into the field faster, while maintaining the high quality that we want.
I'm going to give a couple examples of different types of companies that might use this, and then I'm hoping that you guys can ask me some questions and give me feedback. So example one here would be a small pharma company that typically uses the same 10-20 languages, they don't have that many programs underway and they tend to operate in the same countries, and they tend to use the SF-36v2 standard single-item form for smartphone, and they use the same eCOA vendor for all studies. That's a pretty discrete example, because there are some companies that are very large and they may use tablets, they may use smartphones, they may use many other forms.
Example two is a large pharma company with many divisions that uses several vendors and wish to use all of the standard and acute forms for tablet and smartphone with two of their preferred vendors. So a company like that may have very different questions than the first one.
And example three is a large pharma company that uses five different clinical outcome assessments from us. And they aren't sure how many languages are needed yet. And they want sort of a choose your own adventure library option where they can get up to a certain number of forms, and they're not sure what they are yet.
So that is the idea. So I'd like to know your thoughts, what do you think? Crazy idea? Could we do it? Would it help people?
Thanks Michelle. There was a question here at the back.
From the perspective of translation development during these trials, I think this is a fantastic idea, just because it is such a large pain point for sponsors, in the middle of translation development to hit these review steps that are critically important but can be so time consuming so close to beginning the trial. So I don't have any answers to any of your questions right now, but I think there really great questions.
Okay. Well thank you.
Michelle, I think just on the topic of translations, you hit on the question about whether pharma companies are willing to share, maybe investments they make in a library or whatever between companies. But we see that exact model in translations, right, because you own the translation, you own the IP for your instrument. So Pfizer comes along and says, I want it in this language that you haven't got yet. Well, Pfizer paid for it and then you own the translation. And that's kind of how it works with most instrument authors. And that's acceptable, you know, companies accept that. So why aren't we doing the same with library versions and some of the evidence that we generate around migration validity and all of that stuff? We ought to be able to share that as an industry, even if perhaps one sponsor pays for one thing and somebody pays for something else, or a vendor pays for a certain bit, does it really matter. I'd like to see us moving more towards that approach. And then, when it comes to a library version, we can just have the library version; we don't need a Pfizer library version, and an AstraZeneca library version, and somebody else's. It's just the version. From those who are in the pharma companies, is there an issue with this? Right, okay.
By the way, thanks Bill. I appreciate those comments. And I think, like I said, I say we and our, but I work in the science group so it makes me a bit uncomfortable sometimes, you know, talking that way about "our," because I also would like for everyone to be able to share it, and that's a goal.
I'm in data management in a sponsor company, and I work across all programs, so not all function areas work across all programs. And so I am always budget conscious. So if one program is using SF-36 and we've already paid to have it translated in 15 different languages, why is another program going to turn around with the same vendor and pay for the same translations? And no one is keeping track of that right now. So we could be using the same vendor, two different programs, using the same questionnaire, same version, and we're paying twice.
Well, I would argue that that shouldn't be the way it works, because according to the developer guidelines, the only licensable versions are the ones that we developed. So there shouldn't be other vendors out making lots of—and traditionally we have used a vendor to do it, but we have all those developed. So I don't know who is making bunches—are you talking about the programmed versions, or—
Oh, I was confusing it with actually developing the translations themselves. Okay.
But even so, even if it's programmed already at the vendor and you've already paid for it, why would you pay for it again? Because we already paid, we already own that translation, that work. So there's a lot of inefficiencies, and it could really push along the timelines if everybody knew what the other person was doing and you had a library for each program. In the last company I was at before I left, we were trying to get there. We had done some extensive work on that. And it was close, we were close to finding a vendor to help us do that.
Yes, well we have done it before, worked with eCOA vendors where, no matter who was the funder of the study, once it went in the library it stayed in the library. And that still is completely something that we're willing to do. So it is just a matter of eCOA companies wanting to do that also, without receiving funding from a study sponsor to do it, I guess.
This is about sharing knowledge in some ways. And it's a bit of a pipe dream from the sponsor standpoint. So it's not just eCOA, but also instrument development, scoring algorithms, the whole shebang. So what I have often found is that whereas the HEOR PRO people are very willing to share the instruments across, it's the legal, the brand teams, the legal firms, they're the ones who stop you because—when I was at Novartis, I think it was Abbott, I'm not so sure—we were talking to each other, and they were willing to give me the instrument, we were going to go forward, but then the legal people came in and said no, because in case if our drug development fails for some reason, we could blame Abbott Instruments. Because people who go into legal professions go for a certain reason, I don't know what they are. Sorry if any of your partners are in the legal profession. But they look at things from a very different angle. They think of all the scenarios why things could go wrong. And this is one of the things, and they said, we don't want to—we'd rather spend money developing our own than borrowing from someone else. And when it's the other way around, when we want to share it with somebody else, why do you want to give a competitor an advantage of two or three years while we have spent—I don't know—half a million dollars developing something. I mean so that's the general thing.
Well I want to thank Ari for putting out there some of the things that—what we've heard as we've talked with different groups about this—because I think that really is laying it all on the line of what the issue is in terms of sharing. And you're right. Those are very difficult issues, and I do understand the business cases. And I suffer from being a scientist, so I still want to argue that we have to find a way to make this work. Because it doesn't—I mean I don't mind, I like that we ensure that these things are correct, but certainly our scientific group wants to tackle very deep problems, and form reviews aren't necessarily one of them. So we would love to have more that are in a library and able to be reused over and over again and have that as something that is helping benefit patients in that way. So anything I can do, you can reach out to me and say, you know what, that's a good idea but I don't think this will work because of this, this, and this. And I especially want to hear from eCOA companies also. I've had several conversations but I want to hear from them also because I sort of do see myself as a conduit between all these different licensing, legal, science, vendor, and it's not an easy thing to try to tackle. But I'm convinced that as mundane and boring as it might be, that I'm going to get it done. And people will share one day.
Michelle, I have another question, over here to your right.
Oh Willie, hey!
You said you provide a Word file, which is text strings basically that can be copied, right? Have you considered providing that in another format that can be ingested directly versus having somebody do a menu copy and paste? So I've been looking at this for the last six or seven years to build a library with some of the different vendors in that space. I have actually very high hopes with the [unclear 27:20] ODM format and probably embed it in a blockchain with smart contracts, where you guys don't have to do anything anymore, you just cash your checks, basically.
Well I want to hear more about that. But yes, actually the eCOA companies can keep the library in any sort of format you want. That's what we send out because different groups use different formatting tools, but I would be very interested in having us expand our options of what we could offer into using a tool like that as an option instead. We do--80-90% of our licenses are actually for academic and free in student, which means that they're probably working with SurveyMonkey or something, and so the Word document seems to work the best. But we're more than willing to get those things together for other approaches. So I'd love to talk more about that.
Michelle, thank you very much, that was excellent. Thank you.


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Give new employees and associates a warm welcome with this elegant welcome card. Crafted with shimmery blue cardstock with a soft flourish design plus script that reads "Welcome," this card is a great way to let new employees or clients know you're glad they've joined your team. Lighthearted verses like "We're glad to have you with us!" or "Welcome aboard!" can be printed on the interior of the card, or you can write your own personalized message, if desired. Each card order from Cards for Causes includes coordinating envelopes and a charitable donation to the cause you choose.
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Explore the most romantic spots in East Africa on this 14-day luxury safari. It's a trip you'll remember for a lifetime with magnificent African destinations: Nairobi, Lake Manyara National Park, Ngorongoro Crater, Northern Serengeti and Zanzibar. This itinerary combines a safari experience with an island getaway, perfect for honeymooners or couples….
Tours in Northern Serengeti
The parks in the north of Tanzania are some of the most popular safari destinations in the world; partly because of the opportunity to view the annual Wildebeest Migration from the Serengeti to Masai Mara in Kenya. Northern Serengeti features the plains of the Serengeti, the vast volcanic bowl of the Ngorongoro Crater, the tree climbing lions and flamingos of Lake Manyara and the enormous elephant herds of the Tarangire National Park. The Ngorongoro Crater is a 600-meter-deep volcanic crater, which is home to 30,000 animals with a good chance to see the Big Five in the course of a game drive. Lake Manyara National Park is home to over 400 species of birds including thousands of flamingos inhabiting the shallow waters of the lake. Tree-climbing lions are a peculiar sight in this relatively small park. Tarangire National Park teems with wildlife in the dry season and is strewn with giant baobab trees.
The Circle of Life: Lion King Safari
Feel like the star of your own movie on this luxury East Africa safari to the wildlife reserves that inspired The Lion King. Look for Simba and his friends lying on rocks in Kenya's Samburu, set out on safari drives on the Serengeti plains and experience the exceptional game viewing in…


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Cats and dogs are often viewed as natural enemies, but the truth is that animals of different species often coexist peacefully. Meanwhile, even those of the same species may have spats. The secret to living in peace lies not so much with choosing the correct species as it does with blending the right personalities — and introducing them properly.
In other words, in a household with two cats and one dog, you may have a cat and a dog who are best friends, and two cats who can't be in the same room — or any mix of relationships. The 17 percent of American households who own both dogs and cats can attest that it's very possible for cats and dogs to not only cohabitate but also thrive together.
That being said, not all cats and dogs get along, and some breeds may be a better fit than others, generally speaking, if you're looking to add a dog to your cat-friendly household (or vice versa).
Sighthounds, or breeds that were bred to hunt small animals using sight and speed, such as greyhounds, basenji and Irish wolfhounds, would be an example of dogs that may not be a good fit. Terriers, which also have a strong drive to hunt, and herding dogs, may also rub cats the wrong way. So which breeds are reported as best?
1. Golden Retriever — They're friendly, outgoing and eager-to-please, making them excellent family dogs. Golden retrievers are easygoing and highly likely to adapt to a new living companion like a cat. And while they're playful and energetic, they're gentle and unlikely to be overly rough with a cat.
2. Papillon — Papillons are tiny toy spaniels that weight an average of 7 to 10 pounds. They rarely pose any threat to your cat (whereas a large cat could easily threaten this type of dog), are incredibly intelligent and highly trainable. This means they'll catch on quickly when taught that the cat is their friend, not their foe. Papillons are also outgoing, inquisitive and active — a perfect pal for a lively feline.
3. Pug — Pugs are friendly, affectionate and love attention. Many will happily cuddle up to a cat companion but won't be overrun by even the bossiest of kitties. Known for packing big personalities into their small bodies, a pug can be a great match for the antics of curious cat.
4. Beagle — Beagles love to use their keen sense of smell to hunt, but they're intelligent and can recognize that your pet cat is not their prey. Plus, many beagles are friendly to a fault, which means while they don't make the best guard dogs, they're wonderful dogs for families with multiple pets or small children.
5. Basset Hound — Bassets are usually laid-back and low-key, which means they're unlikely to be bothered by a kitty batting at their tail. These tolerant dogs are known for being agreeable, and even though they can also be stubborn, they'll adjust to a cat-centric household without protest.
6. Labrador Retriever — Labrador retrievers are just as much lovers as they are lovable! With friendly, outgoing and playful personalities, most Labradors can easily keep up with an athletic cat but are gentle enough to interact with a kitten.
7. Japanese Chin — The tiny Japanese chin weighs an average of 4 to 9 pounds but has the agility of a cat. The American Kennel Club (AKC) describes them as "a distinctly feline breed" that's fastidious, graceful and generally quiet"— the perfect cat companion (and cat-like companion!).1
8. Newfoundland — Don't let their large size fool you — newfies are calm, friendly and tolerant (that's why "Nana" in Peter Pan is a newfoundland), and will welcome a cat into the household with open paws. They're known for being sweet-tempered, gentle and highly trainable, all of which are a very good thing given their size, but also make them perfect for cat-loving households.
9. Pomeranian — Pomeranians are affectionate, energetic and about the size of a domestic cat. They enjoy tricks and games and have alert, inquisitive personalities that can keep up with that of even the cleverest of kitties.
10. Bichon Frise — Known for being charming, sweet and affectionate, most of these happy-go-lucky dogs have never met a cat they didn't like! Bichon will welcome virtually anyone into the household, including those from different species.
11. English Bulldog — Despite their rough-and-tumble outward appearance, bulldogs are generally docile and easygoing, affectionate and loyal. Most would happily share their home with a cat or two and typically get along great with other dogs, too. Be aware, however, that bulldogs are often plagued with health problems.
12. Havanese — Havanese attract attention for their long silky coats but are adored for their intelligence and outgoing, funny personalities. These playful pooches tend to adore having housemates to frolic with, and this includes children, cats and dogs alike.
Introductions are everything when it comes to bringing a new pet into your home — especially one of a different species. Avoid the urge to let your new pet have the run of the house right off the bat. Instead, give your dog access to a room or few small rooms only, and be sure your cat can avoid them if he so chooses.
Allow your dog time to acclimate to her new environment before extending the dog gate to an additional room. This room-by-room introduction (often taking up to a week) is also a great way to learn housebreaking habits and also watch your dog's reaction to seeing the cat from time to time, as your cat makes occasional appearances.
For the first official introduction, keep your dog on a leash and lead him toward your cat, but don't force the meeting. Allow your cat to either come toward your dog or go away, and if your dog seems to be getting overly excited, distract him with a treat or a quick walk outside. Introductions may go more smoothly after you've given your dog rigorous exercise and fatigue has set in.
Little by little your pets will likely learn that they can be friends, but don't leave them unattended together until you're sure their relationship is a good one. Even then, your cat should have the ability to escape from the dog at all times if desired, either by jumping up onto a counter or over a baby gate or other barrier that the dog cannot cross.
Keep in mind that you don't need a purebred dog or a puppy in order to become a multi-species pet household. Even the AKC notes, "Most dog breeds can live calmly with a cat if they are socialized as puppies and are trained to leave the cat alone."2
Your local animal shelter is probably filled with dogs who would love to share your home with a couple of cats, and many shelters have cat-testing programs to determine which dogs will do best with felines. The volunteers are usually well-informed as to which dogs would get along with cats — and which would not — so please consider adopting one of these animals in need to complete your pet family.
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HEALTHY PETS DISCLAIMER: This information is for educational purposes only and is not intended to replace the advice of your own veterinarian or doctor. Dr. Karen Becker cannot answer specific questions about your pet's medical issues or make medical recommendations for your pet without first establishing a veterinarian-client-patient relationship. Your pet's medical protocol should be given by your holistic veterinarian.
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https://i2.wp.com/tedxtopeka.com/wp-content/uploads/2015/09/Brian-Thompson-e1441820978666.jpg?fit=536%2C228&ssl=1 228 536 TEDxTopeka Team https://tedxtopeka.com/wp-content/uploads/2018/02/TEDx_logo_TOPEKA_stacked_06.png TEDxTopeka Team2015-09-09 10:00:002015-09-16 15:42:11Brian Thomason: Growing Solutions to Feed the World
Brian Thomason: Growing Solutions to Feed the World
Agriculture is coming to a crossroads with demands outweighing the production. How will the world learn to produce more with the same resources? One way we've found is through technology. Planting smarter and conserving resources will help out. Technology can't do it alone though—what can do you?


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Im a gold terran, playin zerg, and zvz is weird
So i am normally a gold terran player but lately ive been like a plastic league zerg just to have some fun. I've got a question about zvz involving mutalisks. Its not using them that is the problem, it is getting rid of them. I know as a terran it was pretty easy with just some turrents and stimmed marines quickly eat them up.
As zerg though, lings dont attack them. And a mass muta kills spores and queens rather quickly even with transfusing. I gennerally go for a roach festor kind of compostion, with some lings and banelings. I feel stupid to say that I have not joined in muta vs muta zvz. Sometimes i have counterattacked and it gets in because they dont have many ground units but then "oh look a thousand mutas," and then no more roaches, lings, infestors etc.
Im not looking for a build because I dont want to become reliant on one, rather I just want a tip or two to help make my mechanics at zerg better and win more games!
Thanks guys!


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Reserve Bank India (RBI) to replace Rs10 banknotes with coins
It has been advised that the Reserve Bank of India (RBI) plans to gradually replace all Rs10 banknotes with coins. The Rs10 coin was released into circulation in March 2009, alongside the RS10 banknote. It is reported that the current lifespan of an Rs10 banknote is only 9-10 months, which can be a challenge for…Details


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Friday the 9th of February saw the end of our second quarter for financial year 17/18. The team got together to celebrate the successes of previous months and discuss targets for the following quarter. If you have read our blog in the past you'll know that we like to reward the team for their hard work regularly throughout the year and this meeting was no different.
Every quarter staff members are given the chance to get their name in the hat for a number of different challenges, we then draw a name out for each prize. The catagories are as follows:
- Rules of the game (in each weekly meeting everyone nominates a team member as the person you most embodies that weeks rule)
- Above and beyond (staff can nominate anyone in the office throughout the month for going above and beyond their usual role, at the end of the month a winner is chosen based on who's above and beyond stood out the most)
- Sales (the sales incentive changes every quarter, this quarter it was for successfully gaining a new client)
The lucky winners received a bottle of wine and high street vouchers. For 'Rules of the Game' Matt Bennett, Resourcer was selected, and doubling up on prizes Becky Smith, Senior Recruitment Consultant won both the 'Sales' and 'Above and Beyond' prizes.
Usually there are also two prizes, selected by the management team, for the 'Stand Out Employee' of the quarter and the 'Best Sales Person' of the quarter. However, for quarter two it was decided that everyone had worked together as a team and really supported each other through some busy months, so rather than selecting two winners to be rewarded they decided to take the entire team for a meal out.
Congratulations guys, enjoy celebrating a fantastic three months.
Posted 16th February 2018
Town/City: Burton On Trent
Duration: 1 week
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After last year's jarring realization, this year I started a list of books with POC (people of color) and another list of books with a person explicitly not white in the role of a main protagonist in order to track my own reading and hopefully improve upon the lack of diversity of characters in 2015's list of books. This year I read 44 out of 168 books (26%) where any person of color is included, either as a protagonist or a background character, a sort of abysmal quarter but more than 2015's 23% if only barely. Only 16 of those 44 (36% of all books with any POC or 9% of the all the books I read) have a person of color in a starring role, less than half. In some cases, as in Mike Cuarto's Little Elliot books, the protagonist's role is taken by an animal or usually inanimate object, but in most cases the POC play background characters to a white character's story or share a stage where no one is given a spotlight within the pages (for the most part, the covers of such books feature white characters).
A coworker and I both realized recently that the majority of toddler books feature exclusively animal characters–or characters that are usually inanimate objects, like peas. 64 of 168 books (38%) that I read this year are in this category of books with no human or humanoid characters. That means that in 2016 I read more books with completely non-human casts than ones that include even one POC.
Excluding these books that exclude humans and humanoid characters, the total percentage of books with POC rises to 42% but still does not hit even the half mark.
I have this year more actively sought out books with POC as protagonists, but I have not held–I'm sorry to say–to my November resolution to read books only about POC, women, or other marginalized groups. (There's a good new year's resolution for me.)
This is the list of this year's books that included POC. Books where a POC is a protagonist are bolded. Books where a POC is a secondary character, one with a speaking role, and more than a background character but still not a protagonist are underlined. Books which arguably have no protagonist, where for example, a different character is featured on each page have a + sign beside them. Books first published this year have an asterisk, because those are the ones that could be considered for the most recent round of awards, and because those are the books that were probably in some way effected by the current cultural climate.
Picture Books, Picture Storybooks, and Board Books (Ages 0-8)
- A Unicorn Named Sparkle by Amy Young*
- How Do Dinosaurs Stay Friends by Jane Yolen and illustrated by Mark Teague*
- The Dragon Prince: A Chinese Beauty & the Beast Tale by Laurence Yep and illustrated by Kam Mak
- Finding Dory Little Golden Book*
- Finding Dory Big Golden Book*
- Good Night Connecticut by Christian Vrba and illustrated by Anne Rosen+
- Dad School by Rebecca van Slyke and illustrated by Priscilla Burris+*
- Interstellar Cinderella by Deborah Underwood and illustrated by Meg Hunt
- Wherever You Are My Love Will Find You by Nancy Tillman+
- Raven's Light: A Myth from the People of the Northwest Coast by Susan Hand Shetterly and illustrated by Robert Shetterly
- The Adventures of Beekle: The Unimaginary Friend by Dan Santat
- Are We There Yet? by Dan Santat*
- Groundhog's Day Off by Robb Pearlman and illustrated by Brett Helquist
- If You Ever Want to Bring an Alligator to School, Don't! by Elise Parsley
- If You Ever Want to Bring a Piano to the Beach, Don't! by Elise Parsley*
- When Dads Don't Grow Up by Blain Marjorie Parker and illustrated by R. W. Alley+
- The Not So Quiet Library by Zachariah Ohora*
- Strictly No Elephants by Lisa Mantchev and illustrated by Taeeun Yoo
- The Story of Ferdinand by Munro Leaf and illustrated by Robert Lawson
- Moana and the Ocean by Heather Knowles*
- Santa's Sleigh Is on Its Way to Virginia: A Christmas Adventure by Eric James and illustrated by Robert Dunn
- Do Not Bring Your Dragon to the Library by Julie Gassman and illustrated by Andy Elkerton+*
- Step Into Reading, Level 2: Quest for the Heart (Disney's Moana)*
- Little Elliot, Big City by Mike Curato
- Little Elliot, Big Family by Mike Curato
- Little Elliot, Big Fun by Mike Curato*
- The Red Prince by Tom Clohosy Cole and illustrated by Charlie Roscoe*
- It Came in the Mail by Ben Clanton*
- The Most Perfect Snowman by Chris Britt*
- Derek Jeter Presents Night at the Stadium by Phil Bildner and illustrated by Tom Booth
- Marvelous Cornelius: Hurricane Katrina and the Spirit of New Orleans by Phil Bildner and illustrated by John Parra
- Rosie Revere, Engineer by Andrea Beaty and illustated by David Roberts
- Ada Twist, Scientist by Andrea Beaty and illustrated by David Roberts*
Middle Grade-Young Readers (Ages 8-12)
- The World That Forgot How to Dance by Olivia Berrier
- Harry Potter and the Cursed Child by John Tiffany, Jack Thorne, and J. K. Rowling* (the casting director is responsible for making one of the protagonists a person of color; some POC exist as off-screen background characters in an alternate universe within the text, but Hermione's and Rose's races are not specified in the text itself; within the text itself, POC are given a pretty poor treatment)
- The Heroes of Olympus, Book 1: The Lost Hero by Rick Riordan
- The Heroes of Olympus, Book 2: The Son of Neptune by Rick Riordan
- The Heroes of Olympus, Book 3: The Mark of Athena by Rick Riordan
- The Heroes of Olympus, Book 4: The House of Hades by Rick Riordan
- Demigods & Magicians by Rick Riordan
- The Trials of Apollo, Book 1: The Hidden Oracle by Rick Riordan*
- Magnus Chase and the Gods of Asgard, Book 1: The Sword of Summer by Rick Riordan
Teen (Ages 13-19)
- The Mortal Instruments, Book 5: City of Lost Souls by Cassandra Clare
- Looking for Alaska by John Green
Riordan as always has done a great deal to bring up the number of books that I've read with POC protagonists and characters. The surprise aid has come this year from Disney, which not only set a story in Polynesia with an entirely POC cast of characters, but also even in their story about fish in the Pacific, where few human characters were at all present, they were sure to include POC, and in the books mentioned above, I think POC accounted for at least half but maybe 100% of the human characters present. Santat, Curato, and Beaty should get honorable mentions for always including POC among their casts, and Beaty a shout-out for having this year's picture book feature an African American girl. Bildner and Parsley both deserve shout-outs as well for multiple books with POC protagonists. I want to give a shout-out to Gassman too for having an African American on the cover of a book with a quite diverse cast where it would have been possible, as several others chose to do, to feature the white characters on the cover.
I also want to give a mention to Maggie Stiefvater. I've begun to suspect that in her Raven Cycle many if not all of the people in Blue's house are African American, but I can't yet swear to it.
I want to give another shout out here to Elizabeth Bird, who recently published a list of picture, easy, and early chapter books published in 2016 with diverse casts and diverse main characters on The School Library Journal's blog. This is a fabulous list, and fabulously organized. Check it out.
Have I misrepresented any books? Feel free to discuss below. Sometimes–particularly in picture books–it can be difficult to determine a character's race (sometimes probably intentionally so, and I appreciate that too), and sometimes it can be difficult to determine whether a character's role is large enough to merit a place as a secondary character rather than a supporting or background character.


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|Up a level
Stojanović Bjelić, Ljiljana and Slijepčević Babić, Jelena and Nešković Markić, Dragana and Sremački, Maja and Bondžić, Jovana and Vojinović-Miloradov, Mirjana: Drinking water quality in city of Banja Luka, Bosnia and Herzegovina : case study. Proceedings of the International Symposium on Analytical and Environmental Problems, (22). pp. 227-230. (2016)


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Screens and Chests
Marko Košan, 1997
The painting-screens of Sašo Vrabič emerge from elusive vacuum of intangible physical space formed at the outlet of the cathode-ray tube of the TV monitor. Individual uncentered fragments of the cinematically cut images are arranged as a collage on the canvas surface, but none of the counterpoised sections of the ungraspable narration are hierarchically privileged or transformed into icon. The paintings are neither stylistically nor compositionally subjugated to predefined schemes; they are subordinated to the process of recycling fragments of visual messages, to their accumulation and eclectic unquestionability which enable a lucid symbiosis of manifold elements of the fragmentary meta-reality. The syncretism of contents dissolves the concentration of the composed image in the sense of a dramatic, or mythical, narrative impetus. Only its phenomenological particularity, which uncovers the mechanisms of the currently dominant visual communication, is emphasized. Although the stagnancy of the painted fragment perverts the dynamics of the electronic image, its manipulative effects are only the more plainly exposed in the medium in which such a method is not immanent. In principle, imaginary or memory-based referential frameworks could be combined with frozen images, but Vrabič consciously drives them out with his concept of constructing the painting. The still frames of the continuous electronic image are free of the ballast of intellectual sensitivity flowing through the history of culture and art. It ignores the pathetic rhetoric of identification with grand pretexts and models. Images are translated into fine membranes, but taken out of context, they lose meaning and significance. They are swift and elusive, but petrified in temporal instants, and they incidentally stop at Vrabic's canvases, which - just like city hoardings- give away to painted figurative or pattern-like texture only for a limited period of time. Vrabič alludes to the habitual omnipresence of such electronic icons in the modern urban environment which implies alienation and certain distance, and which turns us into passive voyeurs, subject to an inert visual fascination which deposits layers of trivial messages into our subconsciousness.
In the framework of The Artist and an Urban Environment project, Sašo Vrabič did not stop at the fixation on the iconoclastic nature of contemporary visual art; instead, he contrasted chests with fetish objects, safely positioned in the closed world of the self-referential context and personal existential logic, with the impersonal electronic reflection of the fictitious reality. The artist employs temporal categories of memory and the permanent pulsation of the introverted intellect to reflect his own dichotomy between the world of intimate, internal stimuli and the world of the transient "big city street" exploited in the media. In the bipolar perplexity of the expressions of the creative contemplation, which seem to be mutually exclusive, Vrabič's works acquire transcendental dimensions, which place them within the original range of the artistic experience of the world.
Marko Košan, curator, Koroška Gallery of Art, Slovenj Gradec from the exhibition catalogue 'The Artist and an Urban Environment', 1997, p.65-66.
Image: Screen, 1995, oil, acrylic on canvas


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On this classic episode of "The Still Real to Us Show:" "The Champ" Jeff Peck is joined by Captain Obvious! The guys start off this weeks show addressing the latest CENA heel turn rumors and if it could happen this SUNDAY! Then we discuss THE MIZ and if he is living up to his "IT FACTOR" potential! We then sit in front of our FANTASY BOOKING PLAYBOOKS and try to fix the WWE by discussing what they need to do to improve the TAG TEAM DIVISION before we finish this week's show with our predictions for the WWE HELL IN A CELL PPV!
Download the Classic Podcast – HERE!
Podcast: Play in new window | Download
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Meeting minutes:
Wayne Radio Amateur Emergency Team Meeting July 13, 2018
Published: February 06, 2019
Wayne Radio Amateur Emergency Team
Meeting Minutes for 7-13-18
Welcome and start of meeting – Joe K2JVS The meeting started at 7:40 pm. Joe moderated the meeting as Tom, KR2I was absent. It began with a flag salute followed by discussion of agenda items.
Club Business Meeting Topics (Members Only Discussion)
Approval of Meeting Minutes June 8 - Carver W2TFM Minutes approved by majority vote.
Monthly Net report – Aly – AL0Y The net was held on June 27, the 4th Wednesday of the month at 8 pm on the WRAET 2M Repeater. It opened at 8 pm and closed at 8:38 pm.
Aly - NCS AL0Y
Carver W2TFM
Joe K2JVS
Allan KF2EE
Jason W2PX
Allan ANCS K2AJB
Dave K2NEC
John KC2OII
Rob N2RDA
Next net will be Wednesday July 25 on the 2M repeater.
Web Site – Aly AL0Y The Club Bylaws were updated to reflect the Club meeting night and the dues schedule for new members. Field Day pictures are being added.
Aly also discussed the Passaic County ARES.
Membership – Allan K2AJB 25 members have paid 2019 dues. 2 to go. Allan in discussion with NNJ Section Manager to develop recruitment leads.
Hamfest – Dan K2DDG Started planning. Forming committee. Finding outdoor/indoor facility and price.
Social Events – Dan K2DDG Sending out email to members requesting suggestions.
Participation in JOTA October 19-21 – Joe K2JVS Getting church approval. Voted at June meeting to participate again this year with Troop 108. Open to Girl Scouts and others.
Wayne OEM Coordinator for WRAET Club – Mike KD2NCN Mike identified required FEMA courses. Also required ARRL/ARES course.
Here are the links to FEMAs ICS and NIMS courses which are free. An account must be created. https://training.fema.gov/is/courseoverview.aspx?code=IS-100.c
ARRL ARES class
Mike thinks everyone should take the FEMA ICS 100 at a minimum given our focus and interest in participating in emergency communication.
Mike will talk with Capt. Keith O'Sullivan and get his preference on net scenarios (themes). His scenarios will establish "structured" ARES/RACES drills for WRAET nets. Dave, N2NEC to take lead on organizing these ARES/RACES nets.
Projector in meeting room now operational with both VGA and HDMI inputs. All presentations should be done via the media center unit in the corner using the "laptop" button. VGA cable is stored in the podium, connect the laptop and then to the wall below the projector screen.
Field Day Results from June 23-24 – Jack KB2LNO Location was at St Joseph Wayne Hospital – Lots of cooperation from Hospital and Wayne OEM. Hospital also supplied generator and fuel. Wayne OEM supplied generator and fuel, also a large tent for the entire operation. Dave, WO2X provided logging software. Operated with 4 HF stations (category 4A) Banner Design completed by Ariel, KD2ONX. Banner cost around $49 and was approved at May meeting. However, it was never ordered.
Results: 343 SSB QSOs (1 point each) and 63 digital QSOs (2 points each) for a total of 405 QSOs and 467 points for on-air operations. Bonus points added for a number of categories include 4 stations running emergency power and under 150 watts, media publicity, public location, public information table, visit by representative or agency, visit by elected official (Mayor), social media promotion, Safety Officer, GOTA bonus and youth participation. Projected total points (contacts and bonus) – 2,194.
Club Shirts Dave, K2NEC, took the lead on Club shirts – came up with the idea, did the design and selected the shirt vendor. Thank you, Dave, for an outstanding job! Shirts were delivered at the meeting except for Egon, WA2DLZ who could not make the meeting. Carver, W2TFM, is coordinating with Egon.
Open Chair position which requires a volunteer is: Program Chair (meeting programs) required. No programs have been scheduled beyond July. Joe, K2JVS, requested that anyone with a proposed program for a future meeting contact Carver, W2TFM.
Mayor/Council recognition of WRAET Club Joe, K2JVS, indicated nothing to report but still in progress.
EchoLink proposal to Wayne OEM for funding – Joe K2JVS Nothing to report.
Program - was presented by Allan, K2AJB and Dave K2NEC on VHF/UHF digital voice modes including DMR, P25, Fusion, D-STAR, NXDN. Thank you Allan and Dave for an outstanding presentation - very informative!
Other Member business proposed from the floor Joe, K9MBA, described a GO KIT (Gordon – W2TTT variety) and showed cut-out panels of it. Joe offered to fabricate a GO KIT for the club. Thank you, Joe!
GUEST/PUBLIC PORTION There were no guests at the meeting.
Meeting adjourned at 9:15 pm. Next meeting will be Friday, August 10tth, 7:30 pm.
Meeting Attendees
Aly Badawy AL0Y
Allan Jay Baum K2AJB
Dan Giandoso K2DDG
Joe Scuralli K2JVS
David Pandoscak K2NEC
Stan Ekiert K3KKH
Joe Dunphy K9MBA
Jack Carbone KB2LNO
John Demetrius KC2OII
Jamie McCabe KD2LZS
Mike Williams KD2NCN
Piero Mosca KD2ONN
Steven Brodkowitz KD2PJK
Allan Baum KF2EE
Joe Basilicato N2BOZ
Rob Arms N2RDA
Carver Washburn W2TFM
Jason Findlay W2PX
Gary Kantor WA2BAU


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modele de cv pour
Facts, Fiction and How to Write a Formal Letter to a Professor
42 cv de vendeuse
How to Write a Formal Letter into a Professor – What's It?
There are numerous different reasons for which the letter may have to get written. Writing character letters differs from writing many of the company letters. If you want the letter sooner and haven't been in a place to create that sort of rapport, don't worry. Make sure that you clearly specify the main reason for being absent, so the receiver of the correspondence knows of your own circumstance. Well, the expression letter provides a hint. Besides the excellent grades and also the exceptional performance in extracurricular activities, an excellent letter of recommendation will always provide you with the increase you need to get in the college which you dream about.
If you decide to write her a letter, you need to be certain that you are communicating effectively. A letter of absence must explain the most important reason to be absent in addition to define when the worker is predicted to return. Absolutely be sure that your letter is error-free. If you inquire afterwards, expect to obtain a hurried letter which doesn't have the ideal recommendation which may have been. An introductory letter by a new teacher is a procedure of inviting the parents and students to your class and therefore, the tone of this letter ought to be somewhat polite. An introductory letter to parents by a new teacher at the beginning of the academic year is vitally important to develop a rapport with the parents for the remainder of the year.
The Hidden Truth on How to Write an Official Letter to a Professor
Professors are teachers and you've got to follow together with a specific quantity of respect whilst addressing them. Such a professor would be an ideal person to compose your letter of recommendation. If you are able to name particular professors with whom you want to study, do this.
As soon as you have accumulated all of the information, and chose that must compose your letter of recommendation for grad school, you'll get one that will surely be add value to t admission procedure. Your email is most probably neither for them, so you need to make the purchase price of reacting essentially zero. When it is, you might not have to send the email in any respect. If it regards finishing informal emails, there are not any rules in any respect. Never send an email when you're angry. Ending an email which has a good note is always a moral issue to do. You desire the message to be viewed and recognized.
If you're a teacher and are looking for samples slides to get a field trip, you are able to go through them and select the template you prefer. Also tell the reader how you're about the teacher. When it is bullying, an unfair instructor, or something else, your very first step must be to speak with your child's teacher.
You are joining the college for an important moment. If you are aware that you are inclined to be applying to graduate school and you'll need recommendation letters later on, it's a good idea to begin working on building a superb rapport with a professor of this subject you want to pursue further. Most schools and universities restrict the range of times each student may enroll for class so that other students have an opportunity to select the training course. You may be surprised at how frequently students obtain their professor's title wrong. Since school-going students are young and cannot be expected to manage a correspondence about missing class, parents need to take responsibility instead.
The most frequent one is if the child is not keeping well. Similar to cover letters, you have to first write a greeting to the individual you are addressing. Composing it isn't as hard because it's made out to be, however you want to be sure you don't go overboard praising the individual who you're advocating, but provide a great character evaluation. If you're not certain who the perfect individual is within a company, do your best to find out through online research or even a telephone call. In the very first paragraph, introduce yourself and write two or three lines related to that, and also the way you're related to that particular individual. What you write here wants to reflect that you're a serious applicant, and it's done adequate research to comprehend what the group is really working on.
A courteous and meticulously assembled request is far more inclined to get the type of response you desire. When you cover the correspondence and state your goal, include the explanations for the reason you weren't able to finish the course successfully on previous efforts. A recommendation letter is composed as a means to urge someone for a particular opportunity, whereas, a reference letter will be more on the topic of the factual information regarding the individual, without creating any special recommendations.
Every letter you write will differ based on the circumstance, the individual to whom you're writing, and the issues you're discussing. Composing a letter of promotion gets really simple if you own a sample available because it will clearly elucidate for you how a letter of promotion has to be drafted. In most cases the letter needs to be easy and right to the point unless there is need for more explanations. An introductory letter from a brand new teacher is a procedure of welcoming the students and parents to someone's class and therefore, the tone of this letter should be somewhat polite.
In the event the school is unable to help directly with charges, they may be able to aid in different ways. Personal colleges will typically require additional time from teachers outside the school day with several interests. Also search for newspaper articles or district reports to learn as much as you can about the school. Charter schools don't have unions.
Since you may be aware, recess enables student to find exercise, build friendships and take a rest from classroom work. The students will be supplied a rubric with the exact essentials of this project and what the aim of this job is. Necessary Resources The literary work that he chooses to create a collage will ascertain how much time is essential to fully complete the project. Since school-going pupils are young and can not be expected to take care of a letter about missing course, parents should take responsibility rather. Each student must choose one reading that we have done so much or will read in the future, and no two pupils may select the exact same job. Pupils of our college have vouched never to use a cell phone whilst driving and we've made many communities on social networking websites to market the exact cause.
You need to proofread your letter and in the event that you can, ask somebody else to read it as well. The letter you write could make a huge difference in someone else's life thus be sure of what you would like to write in the correspondence and make sure you use the proper format. So be very careful once you draft these letters. This letter is a great example of a recommendation letter for a situation when you need to compose a reference letter for somebody who is applying for work. Besides the excellent grades and the outstanding performance in extracurricular activities, an excellent letter of recommendation will always supply you with the boost you should receive in the faculty that you dream about.
Letters are typically a couple of pages, however they are able to go longer if there's a reason behind the lengthy format. A story-telling letter is a means to make your situation to those that have power to produce decisions and open up the door for greater services for your own kid. As you may see, personal reference letters of recommendation are only a mirror of your character and skills.
In Arms About How to Write a Formal Letter to School Primary? When folks are asked to write a letter of support, however, they might be unsure about the appropriate content and wording. Letters of support frequently earn a difference for applicants no matter what they are applying for. The principal reason for writing a permission letter is to locate somebody's acceptance for some task which you need to undertake. Also once you compose a permission letter, make certain you sign it and also maintain a replica of the letter with to avoid any kind of misunderstanding in the future. Occasionally, the term permission letter can be utilised to symbolize a letter that is being written to permit someone permission to do a particular job, for instance, deciding on a field excursion.
In paragraph , spell out what the letter is intended to pay for. A cover letter may have a logo or small photo of you together with your contact info in the header.
How to Begin with How to Write a Formal Letter to School Primary?
Utilize bullet points when potential to produce the letter a lot easier to read, and clearly say what actions you would like the governor to have your behalf, like asking that he sign a specific bill into legislation. You do not have to write long letters that are long. There are a variety of reasons that one wants to compose a formal letter. Composing an official letter to a mayor is a means to express concerns and supply solutions to issues facing a network.
Such a letter is exhaustive in nature since it provides specifics of this agreement. A cover letter may have a symbol or little photo of you along with your contact data in the header. It is vital for you to understand how to compose letters for specific functions. The goodbye letter really isn't the capability to complain or crib. Normally, enable the goodbye letter reflect positivism. Writing a perfectly phrased letter is not as hard as it is made out to be. First it was be a cordial reminder letter.
Considering that the letter should be properly formatted and carefully drafted, a person ought to take the vital efforts to compose it. The letter of intent suggests that each one of those parties involved with the trade are aware of the deal and all issues associated with it. It's also regarded as a step towards serious negotiation that is to take place before the final transaction. So in the event that you would rather write a letter of intent for work, graduate school, or a real estate bargain, but aren't very sure what to place in your correspondence, then take a look at the examples below.
Letters were the easiest and most economical way of communicating until the invention of the more recent communication technologies. A specialist letter ought to be well-designed with letterhead and your private contact details. Powerful letters will yield only great results. Composing an official correspondence is often believed to be an intimidating task by people. Finally, you should keep in mind that writing an official letter isn't difficult if you know and stick to the fundamental rules and the arrangement of this letter. So, it's crucial to comprehend how to write an official letter effectively. The very first set letter you get from a collection agency needs to have a validation notice.
Franchise Agreements are the deal documents, in which the franchisor grants the liberty to establish a franchise upon several problems. To put it simply, it is the arrangement signed ahead of the last arrangement. Our Non-compete Agreement Templates allow you to specify a time-frame for the deal. Regardless of the fact that there is no formal arrangement, there is an implied contract between them both. Additionally, it is beneficial to be aware of this approach to compose a suitable contract agreement, which covers everything. If you opt to try and compose the contract , be aware that it isn't critical to use legal terminology. Compile all of the details which you'll have to incorporate in the contract in 1 file for your own reference.
For the collection organization to say it had an arrangement on youpersonally, it must demonstrate the way that it was likely to do good for you. It's wise to write down all you need to have in an arrangement so the two parties can definitely know what they are agreeing to. It is true, you signed an agreement by way of your credit card company, but you did not sign one with the firms that purchased your debt out of the charge card business. Additionally, you are very likely to be needed to finish a fee agreement along with your lawyer. If you're writing an arrangement, you have to understand how to compose agreement letters. It is very rare to locate a written arrangement between a car owner and a mechanic, under such problems.
The Importance of How to Write a Letter of Agreement
An Agreement Template enables the companies to bring the form and style of a professional agreement without contemplating much. A company termination agreement is an official document that typically occurs between two businesses, or between a individual and a company venture. Think about whether it is possible to write a contract on your own or in case you are going to want to seek out legal assistance. A company contract is not only among the greatest ways to be sure that both parties know the nuances involved with the market arrangement, but it also helps safeguard your and the other party's interests when entering into an agreement.
The correspondence ought to be kept to a single page in length. An agreement letter is essential as it enables you to keep your legal rights from being violated. After making the necessary alterations, the agreement letter should be submitted to the client. Blank letters of agreement can be found the net, or you will be able to compose your own using Microsoft Word or a different computer application.
Letters are usually a couple of pages, however they can go longer if there's a reason behind the exact lengthy format. A letter of agreement may also be written. It should be concise and it has to present the necessary details in a streamlined format. It's possible to compose your own letter of agreement for many different factors.


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Moisture in the ears
If you have a dog who loves to swim or a dog with extra furry ears, a problem you might encounter is moisture buildup in their ear canals. There are some dogs who don't ever swim, hate to bath who are still prone to moisture buildup due to heredity.
The problem with said moisture is, it can be a breeding ground for a wealth of yeast and bacteria. This buildup of yeast and bacteria can cause an ear infection. Ear infections in our pets can also be caused by mites and allergies they might be plagued with.
Moisture buildup and allergies can also present a third problem. From excess scratching, flapping and rubbing they can weaken the main vein in the pinna/ear flap causing a hematoma. (blood filled pocket)
If an umpire were to judge the dog it would go like this.
Strike 1: Moisture buildup
Strike 2: Infection
Strike 3: Hematoma
Yoooooooooooooou're OUT!!!
If you notice your pup excessively rubbing and scratching at the ear, always see your Veterinarian (Umpire) as soon as possible to see if you are at a "Strike 1" or "Strike 2" status.
If you are prescribed antibacterial or antifungal drops for a "Strike 2" situation, you will find it hard to keep the drops in your dog's ear as they want to shake them out immediately. No Flap Ear Wrap can help keep the drops in the ear canal to let them do their work. We suggest you put the drops in, quickly attach the wrap and remove it after 15-30 minutes. (whatever your Veterinarian suggests) Also if your dog has an abundance of hair in the ear canal, removing it also helps air flow. You, your Vet, or a good groomer can help with periodic hair removal.
A hematoma (Strike 3) due to strikes 1 + 2 is a double-edged sword. You need to stop the flapping so the broken vein will quit forcing blood into the pinna/ear flap causing it to literally balloon out. The ears also need to air out due to the moisture that started the whole thing. The only way to stop the flapping is to keep the ear immobile. The way to keep them static is to wrap them. Wrapping them with a stick to itself gauze type product might work, but the moisture still has no escape. And, nine times out of ten, the pup can unwrap it record time. It can be a vicious cycle.
We have found that you can either get your Veterinarian to prescribe powder such as one called Neo-Predef or as some of our customers have tipped us off to, a calamine based powder called Monkey Butt for ladies (cut with cornstarch not talc) and one called Miracle Care R-7 powder. An alternative to putting powder in the ear canal is to simply roll a large cotton ball in the powder of your choice, using our NFEW, simply place the powder covered ball at the top of the ear canal (don't insert it into the canal) and attach the wrap. This should be done at least four times per day to wick the moisture away.
Keep SAFE!!!!!!!!!!!!!!!!!!


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CHE301 Mid Term Papers Fall 2019
Today's paper of *Che301*
Timming -4:00pm
*MCQ'S was frm past papers*
~*~_Subjective_~*~ -
1-Define analytical chemistry ? 2/
2-Define three type of error ?
3-Wwrite two types of scatter diagram???)
4-Diffrence b/w quality control and quality assurance ?
5-How we prepared sample ?
6-What is precipitation gravimitery ?5/
Reg- *Mishi-Ch*
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- Movies
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New York, 1980: three complete strangers accidentally discover that they're identical triplets, separated at birth. The 19-year-olds' joyous reunion catapults them to international fame, but also unlocks an extraordinary and disturbing secret that goes beyond their own lives - and could transform our understanding of human nature forever.
June 29, 2018


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Remove LamePyre virus (Removal Guide) - Free Instructions
LamePyre virus is a Mac trojan that disguises itself as Discord messaging app
LamePyre virus is a limited functionality trojan that was discovered by security researchers at the end of December 2018. Malware's scripts are run as soon as users launch what appears to be Discord – a gaming community-orientated communications app. OSX.LamePyre seems to be a virus in development with many bugs and lack of obfuscation techniques, and its functionality is limited to running a backdoor on the system and taking screenshots that are sent to Command & Control[1] server. While the capabilities of malware are far from those of modern viruses, the sensitive information leak should warrant LamePyre virus removal as soon as it is detected.
|Programming language
|C2 server
|Use security software Malwarebytes
|Use Reimage Reimage Cleaner Intego to fix the damage done to macOS
LamePyre virus, which is written in Phyton programming language, uses Automator icon when it runs the script, and the gear icon appears on the menu bar with the name "Discord App." Crooks really did a lousy job when disguising the malware, as the shell script does not even show the official Discord logo. OSX.LamePyre then starts taking screen prints and sending them to a remote server controlled by hackers.
Another key function of the LamePyre virus is to run a backdoor on the infected macOS. It uses EmPyre[2] open-source backdoor, which was previously used to distribute the DarthMiner malware. This feature might allow the access of other cyber infections like a worm or ransomware. For that reason, users infected with the trojan should remove LamePyre as soon as possible.
Nevertheless, some security software for Mac might not recognize the threat or fail to eliminate it. Malwarebytes detects and removes the infection automatically. After the elimination, we suggest you scan your device with Reimage Reimage Cleaner Intego – it can ensure the LamePyre's system modifications are reversed.
In order to keep functioning, LamePyre virus runs a launch agent under a misleading name com.apple.systemkeeper.plist. Nevertheless, victims will most likely not realize they are infected, and their machines will already be running backdoors and sending out screenshots to the remote server.
LamePyre virus is Phyton-based malware that takes screenshots and sets a backdoor on the macOS
Avoid malicious software by downloading apps from official sources
While some people might not realize what the difference between an app downloaded from the official website and the one obtained from a third-party site is, others simply act careless and neglect general cybersecurity practices. Additionally, many users opt for torrent and video streaming sites to view copyrighted material for free. However, this type of behavior can easily result in malicious software infiltration.
Therefore, it is vital to use caution, such as:
- Employ anti-malware application and internet security suite;
- Patch system and software with new updates as soon as available;
- Download apps from official sources (Apple Store, Amazon, App's developers sites, etc.);
- Use ad blocker to stop scam messages;
- Beware of fake updates (Flash player[3] especially);
- Use a VPN to protect your privacy.
Remove OSX.LamePyre from Mac to stay safe online
LamePyre malware is a trojan, which means that other malicious programs could have sneaked into your machine without you noticing. Therefore, while the initial malware is not utterly devastating, the possibility of more severe infections should warrant LamePyre virus removal.
To remove LamePyre virus from your macOS, you should perform a full system scan using potent anti-malware software. Malwarebytes is anti-virus application that is capable of doing so safely and quickly. Nevertheless, we also advise you download Reimage Reimage Cleaner Intego to fix up your system and make it run smoothly again.
About the author
- ^ Command and Control [C&C] Server. Trend Micro. Security researchers.
- ^ Thomas Reed. Mac malware combines EmPyre backdoor and XMRig miner. Malwarebytes Labs. Security blog.
- ^ Lory Gil. Malware disguised as Adobe Flash is targeting macOS. iMore. Latest iPhone, iPad, Apple news, deals, reviews, news, and how-tos.
Your opinion regarding LamePyre virus
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Unit4 announces that Grant Thornton UK LLP has signed a five year SaaS agreement for its cloud ERP solution, Unit4 Business World On! to support its finance transformation program.
Grant Thornton UK is a member of one of the world's largest professional services networks of independent accounting and consulting member firms. As such it is a dynamic and fast growing organization and is committed to ensuring its systems and processes keep pace with the ever changing demands of its clients and the wider trading environment.
Using Unit4's cloud ERP, Grant Thornton UK will benefit from a modern platform enabling its finance transformation, enriching user experience for more than 5,000 users and standardizing best practices across 27 UK offices. It will provide Grant Thornton's UK people with better business insights and decision support to enable their business decision making.
Business World On! benefits from the smart technology in Microsoft's Azure's PaaS platform components including predictive analytics, machine learning, event stream analysis and complex event processing. In addition customers benefit from Unit4's new and innovative approach to enterprise computing; delivering more productivity to services organizations, and greater flexibility as business capabilities are accessible via a mobile app. This is what makes it one of the most intuitive, easy to use systems on the market.
"Unit4 Business World will be transformational for us"Mark Reddy, Finance Director for Grant Thornton UK
"Unit4 Business World will be transformational for us," said Mark Reddy, Finance Director for Grant Thornton UK. "We are a people business, fully committed to providing the best systems to support everyone in their work. Business World will touch every part of our business, helping us successfully navigate the business challenges we face. We have been particularly impressed with innovations such as Wanda, Unit4's digital assistant, which will support our people with a self-driving user experience, proactively managing repetitive everyday tasks and leaving them more time to focus on tasks that drive value.
"Unit4 understands and shares our vision for innovation and growth and we are looking forward to a long term partnership with the team to drive our business and its success forward."


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New Tiny Tutorial
With the Halloween season behind me I have been trying to get back into the swing of things. So here is a new Tiny Tutorial about nuno felting. I am going to be starting a Patreon page soon and one of the tiers is going to be for students interested in felting. When they join that tier their reward will include special access to several full-length tutorials that I have made. But for now I hope you enjoy this Tiny Tutorial.
Speed Dying Tutorial
This is an experiment with video tutorials. The video goes by quick because it is mostly meant to show you the process in motion rather than giving detailed instructions. If you have some dyeing knowledge but are trying to figure out how to do a gradient this might be just the thing to get you started.
Why have one color when you can have them all?
A wizard hat or a pixie hood is certainly a unique item to own and wear out to a convention, a festival, or even just to walk your dog around the neighborhood. But when those items are made out of such a wide sampling of bright colors they are impossible to miss! Making a rainbow hat though is not a simple process. This is especially true because I dye the hats myself. Here then is a short history of how I came to make rainbow hats, featuring some recent process photos of me actually adding the rainbow to a rainbow hat.
At the very beginning, when I first offered rainbow items for sale, I purchased my wool already dyed in rainbow colors. I didn't know how to dye myself yet and so buying it already done was the only way I could make the colorful things I really wanted to make. The problem is that really vibrant rainbow colors can be hard to find when looking for wool that has already been dyed. It can also get expensive to pay other people to do that dye work for you.
Eventually, out of sheer frustration with the slow and expensive color hunting I had to do whenever I wanted to make a rainbow item, I really decided to teach myself to dye. Up until that point I had resisted the idea of learning. What little I had read was intimidating, talking about chemical processes, the numerous kinds of dye you could buy, what dyes worked with what fibers, and a whole bunch of other details. Just like how I taught myself to do wet felting though I kept reading and experimenting as much as I could. In the end it simply was a matter of overcoming that intimidating and dunking the wool into the broth of dye to see what happened.
At first it was a mess. Colors were too strong or too weak. Things came out only partially dyed. Dye was spilled all over the place (thank goodness I had a black stovetop). Eventually though I began to understand how long things needed to sit in the dye, the temperatures they needed to be, how to use vinegar, and all the basics. Getting a white hat blank to become another color was no longer magical but practical. It was something I could do for myself.
The next step forward then was learning how to dye my hats with multiple colors. The biggest problem I had to overcome in learning this process was figuring out how to control the dye. Painting or dropping the dye directly onto the wool worked the best for the sort of layering I wanted to do, but working with liquid dye is like trying to take care of a big box of happy energetic puppies. Unless you are tightly controlling that dye the colors will go wherever they want. They will drip through the hat. They will mix. They will swirl. Drips and drops will fly everywhere. I had to learn how to keep everything in its place during the long steaming process, and more than one hat came out with big gooey blotches of brown where the different colors pooled together.
Using bottles (like in the pictures) helps. The dye though needs to be dispensed with tight control. And there is still some likelihood that something random will happen and the colors will mix all together in a way that ruins the rainbow colorway. Then I have to dump the hat into the black dye pot and start again from scratch.
But no one said that making such vibrant colors would ever be easy!
If you are interested in learning more about how to make a hat for yourself check out the tutorial section at my Etsy shop. The tutorials are PDFs that you can easily download after purchase. If you are making your hat for a specific event though give yourself plenty of time. It may take some time to gather all the materials you need, and practice is essential!
By next week I hope to post photos of the finished rainbow hat that I was making in this post. If you want to see how it all ended up come back and visit in a few days!
Digging through my old social media folders I found a video tutorial I made awhile back. In the video I explained how to make a felted cord necklace. Now that I have moved the video to my new YouTube profile I wanted to share it with you!
The Project
This is a pretty simple project for people just starting out with felting. It combines needle felting and wet felting techniques so it is a great way to cut your teeth on both of these types of felting. The basic process allows you to turn wool roving into a solid loop of felted cord. The tutorial uses wool roving that has been hand dyed a bright rainbow colorway, but for your own project feel free to use any colors you want! The best type of wool for this project is merino wool and be sure to avoid buying wool that has been "superwashed" because those kinds of fibers will not felt together.
Materials List
Good luck with your project! If you have any questions about this project please feel free to post or contact me and I will help you so you can make something totally unique with your own hands.
A Little Something More
Once you are ready for a project that is a little more involved check out the felting tutorials that I offer here on my website and Etsy shop. Projects include wool hats, witch and wizard hats, pixie hoods, fingerless gloves, ruffle scarves, and felted bags. Each tutorial is packaged as PDF files with plenty of big color pictures and I am always available if you have any questions.
September 2018


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CF SHOP! card ®
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Located on Level 2, by Entrance 3. L'Intervalle from Montreal offers women's footwear featuring new textures, new colors, new silhouettes and more. Whether you are searching for boots, sneakers, pumps, or flats, that have a style to suit your fashion needs.