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BioMetals (v.28, #3)
Preface by Alvin L. Crumbliss; Katherine J. Franz; Dennis J. Thiele (431-431).
Spoils of war: iron at the crux of clinical and ecological fitness of Pseudomonas aeruginosa by Angela T. Nguyen; Amanda G. Oglesby-Sherrouse (433-443).
Pseudomonas aeruginosa is a versatile environmental microorganism that also causes life-threatening opportunistic infections. At the root of this bacterium's ability to survive in such diverse environments is its large suite of iron acquisition systems. More recently, studies have highlighted the ability of P. aeruginosa to compete with other organisms for this essential metallonutrient. This minireview provides an overview of the iron acquisition systems used by P. aeruginosa, with an emphasis on how these systems contribute to fitness in polymicrobial environments. We also provide an evolutionary perspective of how these systems were selected for in the native habitats of the Pseudomonads, while also highlighting factors that are unique to P. aeruginosa.
Keywords: Pseudomonas aeruginosa ; Iron; Heme; PQS
Acyl peptidic siderophores: structures, biosyntheses and post-assembly modifications by Michelle P. Kem; Alison Butler (445-459).
Acyl peptidic siderophores are produced by a variety of bacteria and possess unique amphiphilic properties. Amphiphilic siderophores are generally produced in a suite where the iron(III)-binding headgroup remains constant while the fatty acid appendage varies by length and functionality. Acyl peptidic siderophores are commonly synthesized by non-ribosomal peptide synthetases; however, the method of peptide acylation during biosynthesis can vary between siderophores. Following biosynthesis, acyl siderophores can be further modified enzymatically to produce a more hydrophilic compound, which retains its ferric chelating abilities as demonstrated by pyoverdine from Pseudomonas aeruginosa and the marinobactins from certain Marinobacter species. Siderophore hydrophobicity can also be altered through photolysis of the ferric complex of certain β-hydroxyaspartic acid-containing acyl peptidic siderophores.
Keywords: Amphiphilic siderophore; Biosynthesis; Acyl peptide; Post-assembly modification
The fate of siderophores: antagonistic environmental interactions in exudate-mediated micronutrient uptake by James M. Harrington; Owen W. Duckworth; Kurt Haselwandter (461-472).
Organisms acquire metals from the environment by releasing small molecules that solubilize and promote their specific uptake. The best known example of this nutrient uptake strategy is the exudation of siderophores, which are a structurally-diverse class of molecules that are traditionally viewed as being integral to iron uptake. Siderophores have been proposed to act through a variety of processes, but their effectiveness can be mitigated by a variety of chemical and physical processes of both biotic and abiotic origin. Processes that occur at the surface of minerals can degrade or sequester siderophores, preventing them from fulfilling their function of returning metals to the organism. In addition, biotic processes including enzymatic degradation of the siderophore and piracy of the metal or of the siderophore complex also disrupt iron uptake. Some organisms have adapted their nutrient acquisition strategies to address these potential pitfalls, producing multiple siderophores and other exudates that take advantage of varying kinetic and thermodynamic factors to allow the continued uptake of metals. A complete understanding of the factors that contribute to metal uptake in nature will require a concerted effort to study processes identified in laboratory systems in the context of more complicated environmental systems.
Keywords: Siderophores; Biogeochemistry; Iron acquisition; Rhizosphere; Micronutrient uptake
The use of hypotransferrinemic mice in studies of iron biology by Julia T. Bu; Thomas B. Bartnikas (473-480).
The hypotransferrinemic (hpx) mouse is a model of inherited transferrin deficiency that originated several decades ago in the BALB/cJ mouse strain. Also known as the hpx mouse, this line is almost completely devoid of transferrin, an abundant serum iron-binding protein. Two of the most prominent phenotypes of the hpx mouse are severe anemia and tissue iron overload. These phenotypes reflect the essential role of transferrin in iron delivery to bone marrow and regulation of iron homeostasis. Over the years, the hpx mouse has been utilized in studies on the role of transferrin, iron and other metals in a variety of organ systems and biological processes. This review summarizes the lessons learned from these studies and suggests possible areas of future exploration using this versatile yet complex mouse model.
Keywords: Transferrin; Mouse; Hypotransferrinemia; Iron; Metal; Hpx
Lessons from bloodless worms: heme homeostasis in C. elegans by Jason Sinclair; Iqbal Hamza (481-489).
Heme is an essential cofactor for proteins involved in diverse biological processes such as oxygen transport, electron transport, and microRNA processing. Free heme is hydrophobic and cytotoxic, implying that specific trafficking pathways must exist for the delivery of heme to target hemoproteins which reside in various subcellular locales. Although heme biosynthesis and catabolism have been well characterized, the pathways for trafficking heme within and between cells remain poorly understood. Caenorhabditis elegans serves as a unique animal model for uncovering these pathways because, unlike vertebrates, the worm lacks enzymes to synthesize heme and therefore is crucially dependent on dietary heme for sustenance. Using C. elegans as a genetic animal model, several novel heme trafficking molecules have been identified. Importantly, these proteins have corresponding homologs in vertebrates underscoring the power of using C. elegans, a bloodless worm, in elucidating pathways in heme homeostasis and hematology in humans. Since iron deficiency and anemia are often exacerbated by parasites such as helminths and protozoa which also rely on host heme for survival, C. elegans will be an ideal model to identify anti-parasitic drugs that target heme transport pathways unique to the parasite.
Keywords: Heme; Iron; Porphyrin; Helminths; C. elegans ; Micronutrient; Anemia
Manganese uptake and streptococcal virulence by Bart A. Eijkelkamp; Christopher A. McDevitt; Todd Kitten (491-508).
Streptococcal solute-binding proteins (SBPs) associated with ATP-binding cassette transporters gained widespread attention first as ostensible adhesins, next as virulence determinants, and finally as metal ion transporters. In this mini-review, we will examine our current understanding of the cellular roles of these proteins, their contribution to metal ion homeostasis, and their crucial involvement in mediating streptococcal virulence. There are now more than 35 studies that have collected structural, biochemical and/or physiological data on the functions of SBPs across a broad range of bacteria. This offers a wealth of data to clarify the formerly puzzling and contentious findings regarding the metal specificity amongst this group of essential bacterial transporters. In particular we will focus on recent findings related to biological roles for manganese in streptococci. These advances will inform efforts aimed at exploiting the importance of manganese and manganese acquisition for the design of new approaches to combat serious streptococcal diseases.
Keywords: ABC transporter; Manganese; Zinc; Cluster A–I SBP; Metal binding; Solute-binding protein; Streptococcus; Virulence
Host-imposed manganese starvation of invading pathogens: two routes to the same destination by Jacqueline R. Morey; Christopher A. McDevitt; Thomas E. Kehl-Fie (509-519).
During infection invading pathogens must acquire all essential nutrients, including first row transition metals, from the host. To combat invaders, the host exploits this fact and restricts the availability of these nutrients using a defense mechanism known as nutritional immunity. While iron sequestration is the most well-known aspect of this defense, recent work has revealed that the host restricts the availability of other essential elements, notably manganese (Mn), during infection. Furthermore, these studies have revealed that the host utilizes multiple strategies that extend beyond metal sequestration to prevent bacteria from obtaining these metals. This review will discuss the mechanisms by which bacteria attempt to obtain the essential first row transition metal ion Mn during infection, and the approaches utilized by the host to prevent this occurrence. In addition, this review will discuss the impact of host-imposed Mn starvation on invading bacteria.
Keywords: ABC transporter; Manganese; Zinc; Nutritional immunity; Calprotectin; Infection
Wounding of Arabidopsis halleri leaves enhances cadmium accumulation that acts as a defense against herbivory by Sonia Plaza; Johann Weber; Simone Pajonk; Jérôme Thomas; Ina N. Talke; Maja Schellenberg; Sylvain Pradervand; Bo Burla; Markus Geisler; Enrico Martinoia; Ute Krämer (521-528).
Approximately 0.2 % of all angiosperms are classified as metal hyperaccumulators based on their extraordinarily high leaf metal contents, for example >1 % zinc, >0.1 % nickel or >0.01 % cadmium (Cd) in dry biomass. So far, metal hyperaccumulation has been considered to be a taxon-wide, constitutively expressed trait, the extent of which depends solely on available metal concentrations in the soil. Here we show that in the facultative metallophyte Arabidopsis halleri, both insect herbivory and mechanical wounding of leaves trigger an increase specifically in leaf Cd accumulation. Moreover, the Cd concentrations accumulated in leaves can serve as an elemental defense against herbivory by larvae of the Brassicaceae specialist small white (Pieris rapae), thus allowing the plant to take advantage of this non-essential trace element and toxin. Metal homeostasis genes are overrepresented in the systemic transcriptional response of roots to the wounding of leaves in A. halleri, supporting that leaf Cd accumulation is preceded by systemic signaling events. A similar, but quantitatively less pronounced transcriptional response was observed in A. thaliana, suggesting that the systemically regulated modulation of metal homeostasis in response to leaf wounding also occurs in non-hyperaccumulator plants. This is the first report of an environmental stimulus influencing metal hyperaccumulation.
Keywords: Cadmium (Cd); Metal hyperaccumulator plant; Iron (Fe); Jasmonate; Insect herbivory; Pieris rapae; Chemical ecology; Elemental defence; Phytoremediation
Speciation of uranium in compartments of living cells by Gerhard Geipel; Katrin Viehweger (529-539).
Depleted uranium used as ammunition corrodes in the environment forming mineral phases and then dissolved uranium species like uranium carbonates (Schimmack et al., in Radiat Environ Biophys 46:221–227, 2007) and hydroxides. These hydroxide species were contacted with plant cells (canola). After 24 h contact time the cells were fractionated and the uranium speciation in the fraction was determined by time resolved laser-induced fluorescence spectroscopy at room temperature as well at 150 K. It could be shown that the uranium speciation in the fractions is different to that in the nutrient solution. Comparison of the emission bands with literature data allows assignment of the uranium binding forms.
Keywords: Uranium; Brassica napus ; Cytoplasm; Plasma membrane; Luminescence spectroscopy; Speciation
Siderophore–fluoroquinolone conjugates containing potential reduction-triggered linkers for drug release: synthesis and antibacterial activity by Cheng Ji; Marvin J. Miller (541-551).
Syntheses of two Siderophore–fluoroquinolone conjugates with a potential reduction triggered linker for drug release are described. The "trimethyl lock" based linker incorporated in the conjugates was designed to be activated by taking advantage of the reductive pathway of bacterial iron metabolism. Electrochemical and LC–MS studies indicated that the linker is thermodynamically reducible by common biological reductants and the expected lactonization proceeds rapidly with concomitant release of the drug. Antibacterial activity assays revealed that conjugates with the reduction-triggered linker were more potent than their counterparts with a stable linker, which suggests that drug release occurs inside bacterial cells.
Keywords: Siderophores; Antibiotics; Trojan horse; Iron transport; Drug delivery; Drug release
Synthesis, characterization and biological activity of Cu(II), Zn(II) and Re(I) complexes derived from S-benzyldithiocarbazate and 3-acetylcoumarin by May Lee Low; Georgiana Paulus; Pierre Dorlet; Régis Guillot; Rozita Rosli; Nicolas Delsuc; Karen A. Crouse; Clotilde Policar (553-566).
Cu(II), Zn(II) and Re(I) complexes have been synthesized with the Schiff base, N′-[1-(2-oxo-2H-chromen-3-yl)-ethylidene]-hydrazinecarbodithioic acid benzyl ester (SBCM-H) which was prepared by condensation of S-benzyldithiocarbazate and 3-acetylcoumarin. The metal complexes were characterized on the basis of various physico-chemical and spectroscopic techniques including elemental analysis and electrochemical studies, and FT-IR, UV–Vis, NMR, EPR and mass spectroscopy. The Schiff base was found to behave as a bidentate ligand coordinating with Cu(II) and Zn(II) in the thiolate form with 1:2 metal to ligand stoichiometry. Crystals suitable for X-ray diffractometry (XRD) were obtained from the reaction of ReCl(CO)5 with SBCM-H forming a centrosymmetric dimeric complex Re2L2(CO)6 linked by Re–S–Re bridges, where S is the thiolate sulfur of the N,S-bidentate ligand. This Re(I) complex is the first metal carbonyl complex with a bidentate dithiocarbazate ligand to have been characterized by XRD. Cytotoxicity assays revealed enhancement of the bioactivity of SBCM-H upon complexation. Both Cu(II) and Re(I) complexes are found to be active against human breast adenocarcinoma cancer cell lines MDA-MB-231 and MCF-7.TOC diagram
Keywords: 3-Acetylcoumarin; S-Benzyldithiocarbazate; Copper(II); Zinc(II); Rhenium(I)
Iron loading site on the Fe–S cluster assembly scaffold protein is distinct from the active site by Andria V. Rodrigues; Ashoka Kandegedara; John A. Rotondo; Andrew Dancis; Timothy L. Stemmler (567-576).
Iron–sulfur (Fe–S) cluster containing proteins are utilized in almost every biochemical pathway. The unique redox and coordination chemistry associated with the cofactor allows these proteins to participate in a diverse set of reactions, including electron transfer, enzyme catalysis, DNA synthesis and signaling within several pathways. Due to the high reactivity of the metal, it is not surprising that biological Fe–S cluster assembly is tightly regulated within cells. In yeast, the major assembly pathway for Fe–S clusters is the mitochondrial ISC pathway. Yeast Fe–S cluster assembly is accomplished using the scaffold protein (Isu1) as the molecular foundation, with assistance from the cysteine desulfurase (Nfs1) to provide sulfur, the accessory protein (Isd11) to regulate Nfs1 activity, the yeast frataxin homologue (Yfh1) to regulate Nfs1 activity and participate in Isu1 Fe loading possibly as a chaperone, and the ferredoxin (Yah1) to provide reducing equivalents for assembly. In this report, we utilize calorimetric and spectroscopic methods to provide molecular insight into how wt-Isu1 from S. cerevisiae becomes loaded with iron. Isothermal titration calorimetry and an iron competition binding assay were developed to characterize the energetics of protein Fe(II) binding. Differential scanning calorimetry was used to identify thermodynamic characteristics of the protein in the apo state or under iron loaded conditions. Finally, X-ray absorption spectroscopy was used to characterize the electronic and structural properties of Fe(II) bound to Isu1. Current data are compared to our previous characterization of the D37A Isu1 mutant, and these suggest that when Isu1 binds Fe(II) in a manner not perturbed by the D37A substitution, and that metal binding occurs at a site distinct from the cysteine rich active site in the protein.
Keywords: Iron; Fe–S cluster biosynthesis; ISU scaffold protein; Iron binding
Human cytoplasmic copper chaperones Atox1 and CCS exchange copper ions in vitro by Svenja Petzoldt; Dana Kahra; Michael Kovermann; Artur PG Dingeldein; Moritz S. Niemiec; Jörgen Ådén; Pernilla Wittung-Stafshede (577-585).
After Ctr1-mediated copper ion (Cu) entry into the human cytoplasm, chaperones Atox1 and CCS deliver Cu to P1B-type ATPases and to superoxide dismutase, respectively, via direct protein–protein interactions. Although the two Cu chaperones are presumed to work along independent pathways, we here assessed cross-reactivity between Atox1 and the first domain of CCS (CCS1) using biochemical and biophysical methods in vitro. By NMR we show that CCS1 is monomeric although it elutes differently from Atox1 in size exclusion chromatography (SEC). This property allows separation of Atox1 and CCS1 by SEC and, combined with the 254/280 nm ratio as an indicator of Cu loading, we demonstrate that Cu can be transferred from one protein to the other. Cu exchange also occurs with full-length CCS and, as expected, the interaction involves the metal binding sites since mutation of Cu-binding cysteine in Atox1 eliminates Cu transfer from CCS1. Cross-reactivity between CCS and Atox1 may aid in regulation of Cu distribution in the cytoplasm.
Keywords: Human copper transport; Atox1; Copper chaperone for superoxide dismutase (SOD); Size exclusion chromatography; Proton-NMR


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Simple Tree Wall Decals For Nursery Ideas
Tree wall decals for nursery are universal and neutral gender to decorate home walls especially kids' room at high valued elegance and beauty. There are some simple shapes for wall designs and decorations. They are all applicable to make much better home background at high valued quality of design and function. Etsy is most reliable place where you can always find the very best pieces of vinyl wall decals in different themes. Tree wall decals for sure to add value of decorative elegance! It is totally unique and attractive when it comes to birch tree wall decal in mural style.
White color is certainly awesome to pour onto black background. Family room and even bedrooms can have the birch tree decals. At Etsy, there are options that each one of them has great details in featuring elegant of design and style to become home wall decor. Family tree, this is what called to birch tree that indeed will make everyone feels represented among family member.
Stencil and wallpaper, the choice is yours to make in how to make better look and feel in your rooms. We have small home with small spaces. Yet by having birch family tree decor on walls, we have always been accommodated when spending moments together. Birch tree wall decor is for sure in adding elegant look and feel in your rooms just like ours. Rustic country to modern contemporary homes can have these birch tree decals. Murals are interesting at high quality of art simply yet high valued. Browse and learn many fine selections at Etsy online.

subset: commoncrawl


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With housing costs skyrocketing by day across the globe not to mention the subsequently high cost of living, many individuals across the nation are financially stretched – with many worrying more about survival than saving a few bucks for a house down payment.
Nonetheless, for these financially strained individuals, FHA Loans may offer a reprieve as these loans allow you to buy a home devoid of stringent financial restrictions.
So what advantages come with FHA Loans?
1. Less stern Credit Score Requirements
Generally speaking, FHA Loans are among the most accessible types of mortgage loans to qualifying for primarily because it accommodates you even with a less than perfect credit score. It is especially comforting for you that has little or no credit history since the overall FHA approval requirements are often less stringent in comparison to other conventional loans.
2. Friendlier debt ratios:
In line with the theme of less stringent approval requirements, an FHA Loan can ease your qualification especially if you already have a significant existing debt amount. In comparison to conventional loans whose limit for any monthly housing debts or any other debt payments is not over 36% of your income, FHA loans boost this figure to around 41%.
3. They Are Assumable
Another benefit that comes with FHA Loans is that it is typically an assumable mortgage. This is to say that if you are looking to put your home up for sale, the buyer may ssume' the existing loan. As such, you can qualify for this loan despite having a bad or low credit as well as if you have previously been foreclosed or been bankrupt.
4. Down Payment Gifts
Numerous different mortgage loans permit down payment ifts.' This is a scenario where a family member lends you funds to cover a part of the overall down payment. Usually, while conventional loans allow down payment gifts, they, however, limit the amount of the gift. Contrastingly, FHA-insured mortgage loans do not limit the down payment ift' amount, therefore, meaning that you can even be gifted the WHOLE down payment.
This is especially advantageous for a first-time buyer who may perhaps not have enough funds to complete a down payment and needs little financial assistance.
5. Simple treamlined' Refinancing
Finally, borrowers who decide to refinance over time may delight in another FHA Loans benefit. These types of loans offer you a treamline' refinance program which is structured to reduce the hassle and paperwork usually allied to the home refinancing process. In fact, FHA Loan treamline' refinance process can be carried out without property appraisals, a component that is necessary for most refinancing situations.
Are FHA loans bad?
Just like any other mortgage, FHA Loans are not short of drawbacks, hence the need to understand both its advantages and disadvantages before jumping into this type of mortgage. Nonetheless, based on the fact that FHA Loans standards are undoubtedly getting more generous over the years, FHA Loans are not necessarily bad. In fact, they are an excellent investment; because of FHA Loans, individuals who are plagued by less than perfect credit, debts, or are facing other numerous financial bumps, can now have the chance to own homes through FHA loans.
If you are hoping to purchase your own home but have tainted credit, or cannot afford the significantly high housing costs, FHA Loans are your best shot since they may just put your home within reach when it otherwise wouldn't be an option.


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Live Well London is organised by Lime Events – a team of event professionals and marketing experts with a wealth of experience organising stylish and experiential events.
The Opportunity
Taking place on 28th February - 1st March 2020, Live Well London kicks off the festival season at an ideal time of year when people are seeking ways to adopt a healthier lifestyle and are actively searching for ways to bring health, fitness and wellbeing into everyday life.
- Engage with a broad visitor demographic of curious, relaxed and engaged consumers looking to explore and engage with wellbeing brands.
- The Live Well London team are event specialists. Experienced, approachable, honest, enthusiastic and looking to work with brands to provide tailored packages, support and promotion throughout the show cycle.
- Extensive and targeted marketing in place to attract consumers who have a genuine interest in health and wellbeing, and are willing to invest in it.
"Live Well London has arrived. The newest and coolest wellness and fitness festival on the scene offering an amazing experience for attendees and brands alike. Simply unmissable"
Shivrav Bassi, Founder, Innermost


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Shmatkov V. V. University as a Technopolis: A Model of SRSTU Strategic Development for Its Current State
A model of university is presented in the article as a model of technopolis. This model is represented as the optimal one for the nowadays technical university's development. SRSTU is shown as an example of successful introduction of the model.
Key words: university; strategy; technopolis; development.
Abramovich A. M. Schemata Based e-Learning
Today's human-readable Web provides a possibility to make an education more comfortable and available for Internet users. Leading developers of e-learning's courseware focus their efforts, mainly, on the creation and recommendation of standards for learning content and associated services as well as on the accumulation and storage of the structured training material. Herewith, the verbal training material's form traditionally obliges the students to concentrate their attention during a long time for the extraction of the semantics and to spend much time in interaction with teachers. Given that in the modern world an education became permanent task, such learning approach ceases to be relevant.
On the other hand, new technologies of the machine-readable Web allow to automate learning activities and to provide semantics of e-learning content in the portable schemes. This article describes an approach of schemata based e-learning that is anchored on the theory of needs, on the model of commonsense reasoning and on the novel method of domain knowledge representation.
Key words: Semantic Web; Linked Data; the need; reasoning; representation of human experience; need satisfaction domain; Linked Needs; semantic portability; and machine-readable e-learning.
Yarovaya N. V., Vitalyeva E. M. Problems of Quality Standards' Introduction for the Advertising Businesses
Using of quality standards for the advertising businesses is a widely discussed nowadays problem. However, in practice these standards are being used not enough widely. One of the main reasons is that this problem isn't worked over well. In the article, authors examine some basic quality standards as suitable and adopted enough for nowadays advertising businesses, or not. They also present a way of creating new quality standard, which should increase the quality level of advertising businesses' work.
Key words: quality system; advertising businesses; synthesis of the philosophy of safety and the philosophy of competitiveness.
Tkachev A. N., Ovchinnikov P. V. Analyzing and Forecasting the Enterprises' High School Graduates Requirements
Authors of the article present a method of forecasting the enterprises' graduates requirements. The method is based on analyzing the personnel movement processes inside the firm, and on using a complex of mathematical models.
Key words: personnel potential; personnel movement; forecasting; mathematical model; numerical methods.
Dulin A. N., Rybalkin D. A. Choosing the Optimum Trader's Strategy for the Decision-Making in the Forex Market
The indicators are being widely used for creating and managing a trading strategy on Forex market. Using a method of simulation, authors of the article prove, that maximum possible positive financial result may be reached by entering the market not on the first, but any other indicator's signal, and the foregoing depends on concrete oscillator. This conclusion gives a chance to make the optimum adjustment of the considered indicators by the criterion of financial result maximization. In article authors consider the following characteristics: RSI, Stochastic oscillator, MACD.
Key words: Forex; trading; financial result; imitating modeling; probability.
Popodko G. I. Essential Conditions for Region's Economy Switching to Innovative and Social Oriented Development
The essential conditions for region's switching to innovative and social orientated development are considered in the article. The resources, skilled workers, industrial and scientific potential is analyzed. The disproportions of industrial and social and economic development are revealed. As a result of research, authors present a SWOT-analysis of set aim realization inside and outside conditions.
Key words: innovative and social oriented development; the region; conditions; obstacles; disproportions.
Perederiy M. V., Borovaya L. V. Aspects for Development of Industry's Providing with Transport in Russia
Some basic principles of developing cargo transportation organization's innovative methods are examined in the article. The conditions of transportation services' market in Russia are also considered. A focus is given to aspects and real possibilities of developing the intermodal transportations in Russia.
Key words: motor transport; innovations; intermodal transportations.
Napkhonenko N. V., Karayeva M. R. Multifactor Optimization of the City's Passenger Transportation System, Based on Using a Genetic Algorithm
Some actual nowadays problems of city's passengers motor transportation are analyzed in the article. The advantages and outlooks for using a genetic algorithm to optimize it are also substantiated.
Key words: city's passengers transportation system; passengers flow; organizing the transportation; optimization models; target function; genetic algorithm; chromosome; gene; population; operator of stochastic variations.
Malova Y. V., Bagrationy K. A., Ivanov M. V.Psychological Component of Public Health Management
Psychological aspect of public health management is analyzed in the article. Medical assistance improvement necessity in the medical institutions is substantiated. An approach to the medical staff and patients' cooperation optimization is suggested. Methodological base is briefly analyzed.
Key words: public health management; medical staff management; psychological approach.
Ilkovsky K. K. Innovative Development of Isolated Power Systems at Various Stages of a Macroeconomic Cycle by the Example of Republic Sakha (Yakutia)
Some problems of exciting the isolated power systems' innovative development are examined in the article. The role of governmental planning, such as a multi-stage energy reform program, is also improved. The imperatives of innovation development of power system in Republic Sakha (Yakutia) are also analyzed.
Key words: isolated power system; the Unified Energy System of Russia; innovation; investment; functions; macroeconomic cycle; the energy crisis; increasing of power consumption level.
Goridko N. P. The Inflation in Ukraine: Regressive One-Factored Models
The influences of different macroeconomic indexes on the price increasing in Ukraine are determined in the paper. There were elaborated some regressive models expressing the dependence of inflation rates upon each factor under constancy of other ones. The main pre-conditions of inflation arising in Ukraine are marked.
Key words: inflation; regressive model; aggregate supply; macroeconomic adjustment.
Demidova N. Y. Working out the Methodological Approach to Estimation of Work Efficiency, Based on the Indices of Quality, Productivity and Profitability of Business Activity for Personnel Certification in Coal-Mining Organizations
The article deals with approaches to estimating work efficiency of employees in coal-mining organizations on the basis of indices of quality, productivity and profitability. A method of complex estimation of work efficiency is also presented.
Key words: staff certification; quality; work productivity and profitability; complex estimation of work efficiency.
Aleksandrovskaya L. A. Basic Foundation of Managing the Conditions and Protection Activities for the Water Conservation Systems' Environment
Switching to market economy gives a reason to great changes in the relations between the ground area owners. Nature of the ground area owner becomes a meaningful question. This problem has a number of historical reasons. In the article author examines nowadays forms of ground area owning and ways of nature management.
Key words: ways of managing; market economy; ground area owning; relations of the land tenures.
Ovchinnikova N. G. Basic Social, Ecologic and Economic Lands' Properties and their Affect to Regulation of Land Sources Use
In the article author presents some conceptual approaches to creating rational and effective utilization system for ground resources of agricultural purpose in view of economic forces at a stage of transformation the economic, ecologic and social relations in agricultural sphere.
Key words: ground resources; social, ecologic and economic properties; investment potential; ecological funds; nature protection activity; financing.
Satvskaya E. A. Analyzing the Ways of Wastes Utilization at the Wrapping Production Enterprises
Author of the article analyzes Russia's market of wrapping materials. The increasing of competition between the consumer goods (firs of all — foodstuffs) manufacturers, forces the wrapping materials manufacturers to increase their marketing activity and pay more attention to product's quality. This situation makes the wrapping materials manufacturers to revise the branch's development strategies in Russia's regions, and begin to create «the wrapping complexes» in these regions.
Key words: wrapping production enterprises; composite materials; dynamics of the development; paper materials; fast income segments of the economy.
Moskayev S. A. Dealers' Activities as an Innovative Factor for Economy's Institutionalization in a Post-Crisis Period
Some features of dealers' activities as of an innovative factor for Russian economy's institutionalization in a post-crisis period are examined in the article. The tasks for investigating the dealers' activities as an institutional reserve for compiling the innovative model of Russian economy are also defined.
Key words: dealers' activities; innovations; institutional economy.
Piterskaya L. Y., Tlisheva N. A. Theoretical and Methodological Aspects of Governmental Support for Agrarian Branch of Economy
The article deals with theoretical and methodological aspects of governmental support for agrarian branch of economy. Authors also assign seven subsystems of the concept of stable economic development, and show the importance of differentiated approach to the provision of governmental support in modern conditions, basing on factor analysis of the share of subsidies and the volume of earnings.
Key words: agrarian branch of the; stable development; the concept of antirecessionary development; the state; efficiency and correctness of governmental support to farmers; subsidies; earnings; factor analysis; district; small, medium and large agrarian business.
Tkalich G. I., Besfamilnaja E. V., Dmitrieva E. V.More about a System of the Educational Institutions' Financing for the Modernization Conditions
A problem of the educational institutions' financing becomes an actual one in a period of modernization. The opportunity of using a fundraising as a tool for attracting the additional financial assets, to make the higher education institution's work effective and increase the education quality, is presented in the article.
Key words: fundraising; financing; institutions of higher education; modernization.
Komissarova M. A. Actual Problems of Formalizing the Enterprise Management Systems
Some basic approaches to researching the enterprise management systems are considered in the article. The possibilities of using a new methodical approach to managing Russian industrial companies are also offered. A modern concept of managing an industrial enterprise, based on the positions of complex approach, and on using a system of balanced scorecard as one of the basic management tools, is considered.
Key words: management systems; a complex approach to management; balanced scorecard.
Efimov A. V. Some Features of Managing the Intellectual Property of Technical University
Some features of managing the intellectual property inside the structure of technical university are examined in the article. The ways of valuating the intellectual products, which products are being created during the researching and educational processes, are also presented.
Key words: intellectual property; management; valuation; university
Hachac M. G. Investment Potential of Nature Protection Funds as the Important Factor of in Nature Protection Activities' Financing
In the article author considers the ways of toughening the requirements to organizations and people, which's activities result to pollution of the environment. Author presents the decreasing of taxes, accounting the expenses on nature protection actions as the taxes, and developing cooperation with tax inspectorates as the ways of exciting the businesses' environmental protection activities.
Key words: investment potential; nature protection funds; nature protection activities; financing.
Deryabina E. V., Abrashkin M. S. Prerequisites for Healing a Labor Rationing System as a Factor of Increasing for Labor Productivity and Economy's Sustainable Development
Some actual problems of labor productivity increasing in view of nowadays economic conditions are examined in the article. It's disclosed that a kea factor, which determines the labor resources' effectiveness, is labor rationing. Nowadays this rationing at the enterprises of different branches of Russia's economy works poorly because of destination and system structure loss. During the examining of theoretical and methodic basis, authors discover five main ways of labor rationing system's improving, which ones should increase its productivity.
Key words: labоr; labоr prоductivity; labоr ratiоning; efficiency оf the wоrkfоrce; human resоurces management; labоr standards.
Agafonov D. P. The Time Management Optimization on the Basis of the Modern Management Technologies
In the article results of corporate and personal time management system creation at the enterprise of building branch on the basis of the project management system are presented. The system raises efficiency of resources planning, monitoring and the task performance control.
Key words: time-management; planning; monitoring; control; project management.
Pyryaev V. V., Draka O. E. Mathematical Methods and Models to Manage the Enterprise
Some actual tasks of enterprise management in the conditions of uncertainty are considered in the article. The described conditions take place ion when the information on the situation either is insufficient or probabilistic. The function of an accessory is developed, basing on processing the statistic data. The received function of an accessory can be used for preparation and choice of the rational decisions in sphere of production control and especially forecasting and long-term planning.
Key words: function of an accessory; mathematical methods in economy.
Moskayev S. A., Gavrilov A. V. Providing the Innovative Processes of the Dealers' Activities with the Information
Some features of providing a management of the innovative processes with the information during organizing of the dealers' activities are examined in the article. A new interpretation of managing the information during the innovation processes, which processes take place when the dealers work, is also presented.
Key words: innovations; dealers' activities; information.
Polyakova O. V. Calculation of Potential GDP, Phillip's Curves and Okun's Law Econometric Estimation (by the example of Kazakhstan Republic)
The article considers potential GDP estimation for economic of Kazakhstan by using technique of substitution. It is making Phillip's curves estimation by monthly data, that permits calculate non-accelerating inflation rate of unemployment (NAIRU). The article contains econometric estimation of Okun's law on basis of obtained dynamic series.
Key words: potential GDP; Phillip's curve; non-accelerating inflation rate of unemployment (NAIRU); Okun's law; regression models.
Lozovskaya T. A., Sklyarova I. Y. Investments in Development of Russia's Fuel and Energy Complex
Authors of the article worked out a mechanism of public investments in Russia's power engineering branch. They also examine the conditions of Russia's fuel and energy complex, and suggest some possible ways of financial support for its development, and mechanisms of financing.
Key words: fuel and energy complex; strategy of public investment; prospect of the coal industry's development; governmental policy in power engineering.
Tsapko K. A. Development of Value-Based Management System for Design Companies of Road-Building Complex
The most important economic and organizational features of the road-building complex, which effect the formation of its design companies' value-based management systems, are considered in the article. A value-based management cycle for design companies of road-building complex, which is worked out basing on these features, and the analysis of the cycle's elements, are also presented.
Key words: value-based management; design company; road-building complex.
Reuk A. M. Managing the Stakeholders' Interests during the Industrial Enterprise's Bankruptcy Procedure
The article contains a description of stakeholders' interests managing principles, during the industrial enterprise's bankruptcy procedure. Description is based on the author's model of estimating the affect of interests on process and results of bankruptcy procedure.
Key words: bankruptcy; stakeholders; managing the interests.
Gortsevskaya E. A. Effectiveness Estimation for the Production Company's Informational Sources
Some features of nowadays production companies' informational sources and ways of effectiveness valuation during the informational and economic projecting and managing the production systems are examined in the article.
Key words: information; effectiveness; cost; managing the infomational sources.
Danilov E. A., Slavinskiy V. A. Decreasing Risks during Equipment Delivery and Commissioning Organizing at the Industrial Enterprises
A way of decreasing investment projects' risks, which take place during creating and achievement delivery or modernization of the manufacturing equipment at the industrial enterprises, is presented in the article. The way is based on using a system of EPC-contracts.
Key words: investment risks; industrial enterprises; fixed capital; manufacturing equipment; EPC-contracts.
Rezunik A. V. Information Streams of the Enterprise's Internal and External Business Environment
The analysis of the enterprise's external and internal business environment, as the examining of all its factors, gives a chance to notice the factors' division into two groups. Factors of the first group can be managed by a businessman, and ones of the second group can't be managed. This division is important for acceptance of administrative decisions.
Key words: business environment; a businessman; information streams.
Kuzina O. V. IT-Technologies for Reenginiring of Business Process in High School
The effective management of business processes creates the basis for synchronization of objects inside the organization and at the same time provides an effective process of commercialization of scientific and technological activities. In order to improve its performance high school must use an architectural approach and promotion of IT-technologies (applications). With this object in mind in the article are offered the structure of business processes of high school and the steps of transition's process from business architecture to IT-architecture.
Key words: reengineering; business processes; information systems; information technology; IT-architecture; business architecture.
Kuzina O. V. IT-Technologies for Reenginiring of Business Process in High School
The effective management of business processes creates the basis for synchronization of objects inside the organization and at the same time provides an effective process of commercialization of scientific and technological activities. In order to improve its performance high school must use an architectural approach and promotion of IT-technologies (applications). With this object in mind in the article are offered the structure of business processes of high school and the steps of transition's process from business architecture to IT-architecture.
Key words: reengineering; business processes; information systems; information technology; IT-architecture; business architecture.
Selyaev E. V. Creating a Competitiveness Strategy for the Human Service Businesses
The basic statements of creating a competitiveness strategy for the human service businesses are examined in the article. A strategy of development is analyzed from the position of innovative development and looking for the ways of modernizing product, service or manufacturing equipment. Author presents an algorithm of working-out and introduction the competitiveness strategy, which algorithm gives a human service business a possibility to make a model of its market behavior on the stages of strategy's preparation, introduction and realization. Choosing the optimal policy assures business the best financial conditions for a long period, and profitable market positions.
Key words: services; competitiveness; strategy; innovation; flexibility.
Chepurin P. A. Informational Sources of the Enterprises and a Problem of Competitiveness
Some ways of increasing the nowadays industrial enterprises' competitiveness, which ways are based on perfecting the informational sources, are examined in the article. The informational basis of business's innovative and competitive advantages, presented as the company's internal information, is also analyzed.
Key words: industry; competitiveness; informational sources.
Savchuk V. F. Basic Ways of Rational Using Funds for Nature Protection
In the article author presents a review of economic problems, which occur during nature protection measuring, social and economic meaning of nature management. These features, author says, should be presented as a part of production's social costs, and of regions' and municipal formations' intentional development programs. Economic effectiveness of nature protection programs should appear as a result of people's interaction during the material production processes.
Key words: nature management; nature protection costs; natural resources; monitoring of the environment; economic and social result; regeneration of natural resources; economic results of the environment protection.
Fediunin V. V. Effectiveness and Ecological Requirement for Heat-and-Power Engineering
Some features of ecological conditions based effectiveness estimation for heat-and-power engineering technologies are examined in the article. It's shown that heat supply's affecting the environment depends on heat supply sources' and networks' features.
Key words: environmental protection; effectiveness of power engineering; heat-and-power engineering; manufacturing pollutions of the environment.
Sung Y. Chinese Entrepreneurs in Russia as a Social and Professional Group, and their Economic Interests
Some social features of Chinese citizens' business undertaking in nowadays Russia are examined in the article. The habits of business existence, in which one the Chinese capitals are invested, are also considered.
Key words: Chinese people in Russia; business undertaking; social and professional group.
Didenko А. А. Professional Structure of Russia's Inner Forces
Some ways of studying a professional structure of inner forces as of a social institution are identified in the article. The possible problems and prospects of research are also analyzed.
Key words: professional structure; profession; inner forces; professionalism; social and professional groups.
Chelpanova D. D. A Theory of Social Protest and Modernization Effects
This article discusses a theoretical model of protest activity's determination, covers all stages of the protest potential formation, its actualization and transformation to a social protest. This model is presented as a part of the theory of social modernization; it is displayed in the context of the contradictions between legal and legitimate social institutions and practices.
Key words: legality; legitimacy; modernization; protest potential; social tension; social protest; protest activity.
Lyovkina N. V. More About Problem of Institutional Interaction Between Religion and Govermnent: Social and Historical Angles
Author analyses the problems of interaction between religious and governmental institutions in Russia's history from different points of view. A great attention is paid to Soviet period of Russia's history. It's stated that a great number of Soviet Union citizens stayed religious, and reproduced their religiousness to the next generations, contrary to assumed atheisation of society.
Key words: social institutions; religion; state; USSR; atheism.
Tishchenko Y. G. Gender Studying of Present-Day College Students in Russian Sociological Sciences
The article proves the importance and significance of gender studying of the present-day students at the institutions of higher educational in nowadays Russia. Author also presents the main results of analyzing Russian sociological publications on the problem of gender stereotypes of Russian students' consciousness. Besides, the article determines the so-called «theoretical niche», i. e. the direction and perspectives of further working out of the problem mentioned above in Russian youth gender sociology.
Key words: gender research; gender stereotypes of students' consciousness.
Polyakov A. N. Russian Non-Governmental Counter Drug Addiction Organizations, as a Factor of Country's Social Capital Increasing
Some features of Russian non-governmental counter drug addiction organizations, which ones are a factor of increasing country's social capital, are analyzed in the article. The results of author's sociological research, based on an opinion poll among students and young people, are also presented.
Key words: drug addiction; social capital; institutional confidence.
Mogilinets N. N. Generalities of Long-Term Preparation Program for Single-Combat Sports
A number of social and educational approaches of organizing a long-term preparation for single-combat sportsmen are examined in the article. Some ways and concepts of organizing the training processes are also presented.
Key words: sports; social and educational methods; a process of trainings.
Donchenko E. V. Social and Economic Features of Fabrication and Selling Wellness Products and Services
Some features of fabrication and selling products and services for health care, also known as Wellness products and services, are examined in the article. It's proved that investigating social and economic perspectives of their work are of theoretical and practical interest, and can help Wellness businesses to increase its effectiveness and to crack some social problems of nowadays Russia.
Key words: Wellness business; effectiveness; social functions; social groups; motivation.
Revunov R. V., Revunov S. V. New Ways of Identifying Social, Ecologic and Economic Damages
Authors of the article examine the compensation mechanisms of social, ecologic and economic damages on macroeconomic level, which damages exist as a result of inefficient nature management.
Key words: damage to the environment; nature management; environment; an ecosystem.
Ivanova А. А. Changes of Citizens' Economic Behavior in Russia's Transitive Society
The brief discourse of economic behavior transformation in a transition period is stated in the article; two major factors, which affect a level of Russia's transitive economy participants' rationality, «external information limits» and national economic mentality of Russians in the beginning of the «transition» are also considered. The attention is paid to behavioral principles, which were a base for accepting the economic decisions by Russians in 1990th.
Key words: transitive economy; mentality; rationality; economic behavior; opportunism, market reform.


text: Sozo Saturday's have been moved September 14, 2015 by Lis Schmidt 0 Comments0 Comments We will now be meeting on the second Saturday of the month. Next meeting is Oct 12! Please follow and like us:Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Like this:Like Loading... Related


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The ATX Podcast Book Club is exactly what you imagine it to be. A club of podcast listeners that choose the podcasts for the month and come together to discuss them and share standout moments from their favorite podcasts!
Our first event is a Meet & Greet set for Jan 15th.
If you love podcasts and you're burning with desire to talk about them with someone, I've got the club for you!


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Most enterprise persons have got color enterprise card stamping printed 2 times or 3 x annually. According to their sort of business, they want to do that given that market and also bigger monetary forces might need you to be able to update yourself plus your image rapidly to have start upwards business associates.
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Like some other templates regarding printed substance, color enterprise card templates supply a easily approach to change little issues with design boost it for almost any new set of stamping. You will see the reason you must attempt establishing this up on your own personel models too.
Why could you use web templates? – Enterprise card templates provide time to be able to rapidly re-think and also redesign the image through every time of year. For illustration, there could be an unexpected change in the industry climate in which changes the particular census with the clients and also business associates. From the typical market regarding professionals, your industry might switch with a largely feminine professional market, or possibly a mature more "veteran" enterprise crowd.
Inside these circumstances, utilizing any template to be able to rapidly upgrade and art print will demonstrate useful. Inside a short time, you have the ability to retool your business strategy to make sure that you indulge more while using the new census with the market. Templates essentially provde the versatility to improve your graphic within nights to swiftly exploit any business possibilities which could arise.
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AbleData does not produce, distribute or sell any of the products listed on this website, but we provide you with information on how to contact manufacturers or distributors of these products. If you are interested in purchasing a product, you can find companies who sell it below.
The Anus Stimulator, model H72512, is designed for persons with spinal cord injuries and other paralyzing conditions to assist in regular bowel function by direct mechanical stimulation of the rectum. The stimulator can be used by individuals with flail hands and fingers. The device consists of a rectal probe made of Delrin plastic which reduces the shock normally experienced from cold metal devices. It has a polyethylene collar which is adjustable to shorten the depth of the probe. The adjustable holding clamp is made of plated steel to form a handle which has a Velcro closure strap with plated metal buckles to accommocate the hand of the user. The probe may be washed in hot water and chemically sterilized. DIMENSIONS: Overall length is 8 inches; probe is 3.5 inches long. WEIGHT: 3 ounces.
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Refrigerated trucks are a large investment. With that being said, it is important that when operating a refrigerated truck business that you have adequate coverage. Gould has over 100 years experience in the field. For a free quote give us a call today at (386) 734 3970
Having the right reefer coverage is there for you in the event of accident or equipment failure and you are held liable for spoilage. Transporting refrigerated goods without them going bad is your business. However, things go wrong.
As an independent Reefer Truck Insurance Agency we present a clear advantage over the competition in that we are able to survey the entire insurance market and tailor a policy specific to your needs.
To speak with an agent at Gould today in regard to your Refrigerated Goods Trucking Business feel free to give us a call today at (386) 734 3970


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My in-laws run a wilderness camp called Discovery Ministries. It is a ministry that helps people overcome personal challenges and conflict. Being a ministry, it obviously focuses on placing trust in God while pushing people out of their comfort zones. They lead challenge trips, which involve hiking in the wilderness for day to a couple of weeks; facilitate group discussions and interpersonal conflict sessions; and offer retreat and camping facilities. At the core of their philosophy is the use of experiential education to bring about personal growth—mentally, physically, and spiritually.
I value their work. The United States is a country that has begun to lose its connection to the natural world. We are lost without our televisions or smartphones. We have difficulty relating with one another despite greater technological connectivity. And I feel that the church in the United States desperately needs growth—mentally, physically, and spiritually. I worked in a Christian book store and encountered many people who couldn't deal with conflict. Many of the Christians I have encountered are passive aggressive—we kill with insincere kindness. We have also made our faith into one of head knowledge, often bypassing the heart (except when singing worship songs or reading Christian literature or feeling good about how much God loves us), especially when it comes to relating to people who do not share our beliefs. We like to box ourselves in a safe Christian bubble that constantly reaffirms our beliefs and (more importantly) our feelings. We have often ignored the practical aspects of Christ's teaching: forgiving others, loving others, caring for others, and having mercy on others. We tend to proclaim what we think is best for the world, always within the safety our Christian bubble.
This is why I value the work of Discovery Ministries: they encourage Christians (and those who are not Christians) to deal with the difficulties of life by taking them out of their comfort zone. They provide an environment that fosters encouragement, growth, challenge, and forces people to actually relate to one another.
Next month I will be participating in a 24 hour hike-a-thon for Discovery Ministries. They rely on donations to pay salaries and maintain the facilities around the camp. They recently built a new office area. It is usable, but they do not have the money to finish it.
I've set up a fundraising page on Indiegogo. I'm hoping to raise $500 for the ministry. My hiking goal is 20 miles. I have a few incentives that I am offering, specifically writings that I have done. I would appreciate it if you check out the campaign and consider donating as much as you feel you can.


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Immediately upon seeing the movie, I knew that I wanted to share my thoughts and feelings with other women and, more importantly, hear your thoughts and feelings. I had seen the play many, many years ago like a lot of people, so I expected a lot of it. I expected the heart of the play to be respected. I needed that because I saw the play shortly after reconciling my own suicide attempt. I saw the play when I needed the play. So here comes this movie…and, again, I expected a lot.
So join us and let's talk in room full of women of like and different minds. Bring your diversity of thoughts, your intensity of emotion and an open mind to hear how others have been moved by the movie.
(Light refreshments served)
Little 5 Points Community Center, Suite 108
1083 Austin Ave.
Atlanta, GA 30307
Tuesday, November 30th


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By Larry Pribyl, DDS
Forty four million people in North America suffer from symptoms of TMD (temporomandibular joint disorder). This can be characterized by jaw pain, ear pain, headaches, ear stuffiness, popping and/or clicking when eating and/or talking, an inability to open your mouth wide or an inability to close your mouth completely.
Understanding How the Jaw Joint Works
To help you understand how the jaw joint works, gently place your little fingers in each ear canal while you open and close your mouth. You will be able to feel the motion created. Is it a smooth movement you feel or is there a popping, grating or cracking feeling? Open your mouth slightly. Move your jaw from side to side and experience a different movement. Now see how wide you can open your mouth without pain. Can you place 3 fingers (one on top of another) into your mouth without hurting? Do not force the opening. If you cannot open your mouth this wide without pain, it could be a sign of TMD.
If you hear a clicking or popping noise in your jaw, it more than likely means the cartilage disc in your jaw is slipping in and out of place. Sometimes it is a result of trauma, like whiplash from a car accident or from falling and bumping your jaw. If the traumatic incident is strong enough, it can cause a dislocation of the disc. It is very common that popping will start immediately after an accident. If you experience popping while chewing, and the popping goes away, you may notice an increase in pain and a decrease in your ability to open your mouth. If your jaw feels "stuck" or "stiff" in the morning, it may also mean that you have a displaced disc. If the disc returns to its original position, then the popping will stop. However, the popping also stops if the disc loses its ability to go back into its original home position. At this point, you will notice a sudden decrease in your ability to open. Some people cannot open enough to get a spoon in their mouth. It can affect anyone and to varying degrees.
Treatment Options
If you find yourself in this position, moist heat, muscle relaxants, anti-inflammatories, soft diet and making a conscious effort to keep your "lips together and your teeth apart" can give you some relief. After several days, if you continue to notice a limited ability to open your mouth, I would encourage you to call our office so we can offer some assistance. Sometimes we do a manual manipulation that can help restore your range of motion. There are times too that we need to custom make an oral appliance so the disc can be repositioned back to its normal position.
We see many patients who have the cartilage displaced. Just a bit of advice: the longer you wait before you seek treatment for this, the more difficult it can be to get complete repositioning of the disc.
To learn more or to schedule an appointment for an evaluation, please call our office at 816-795-1000, or visit us online at www.tmjsleepapnea.com. You may also email questions to Cetta in our office at:
Larry Pribyl, DDS, has been in private practice over thirty five years. He has his Master of Excellence: American Academy of Craniofacial Pain, he is a Diplomate: American Board of Dental Sleep Medicine, and a Diplomate: Academy of Clinical Sleep Disorders Disciplines. He specializes in treating head, neck, and facial pain as well as dental sleep medicine. His training comes from experts in these fields where he has acquired hundreds of continuing education hours in post graduate studies.


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Valuable and Limitless: Lessons Learned as a FUTURE Participant
Valuable and Limitless: Lessons Learned as a FUTURE Participant
Sharon Lee
When I first joined the FUTURE Program as a 2nd-year graduate student who was yet to take her qualifying exam, I was one of the youngest people in my cohort. It was evident from the first FUTURE Program workshop that I had no idea what I was doing there, while others in our group had clear goals of what they wanted out of their time in the FUTURE program. Now, as a 3rd year Ph.D. candidate who just had her first thesis committee meeting, I feel fortunate to have participated in FUTURE. The FUTURE experience changed my perception on what I could and should be doing as a graduate student, and I will forever be grateful for it.
I am a proud immigrant, first-generation college student, and now the first and only one in my family to pursue a Ph.D. in STEM. Throughout my educational and professional journey, I have always had to fend for myself when it came to academics. I chose to major in a subject field that my parents were completely unfamiliar with. It was hard, but I did not let the challenges deter me. Likewise, when I started graduate school at UC Davis, I naturally continued to advocate for myself as I did when I was an undergrad. I looked for opportunities that would help me grow as a scientist beyond the lab, and participation in the FUTURE program was one of them.
FUTURE provided a safe space for all of us – graduate students and postdocs – to have an open dialogue about topics that worried us, like our future. There were a lot of lessons we learned during the 10 weeks that we spent together. I realize not everyone has access to this kind of intensive program and thus, for my fellow researchers in training, I want to share two of the most important lessons that I am grateful to have learned from FUTURE:
You are a valuable asset
The most gratifying moment I encountered during FUTURE was when I realized that I am a valuable asset. As scientists, we are not trained to acknowledge our accomplishments or take a moment to appreciate how far we have come. So, it is not surprising that when it comes to advocating for ourselves, we fall short. For our FUTURE workshop on transferable skills, I still remember sitting there, wondering to myself whether I could do anything else besides working in a lab. I have worked exclusively in labs all my life and I am still training to become a better scientist. Little did I realize that in addition to learning how to meticulously pipet precise amounts of solutions, I am picking up so many other capacities in graduate school.
Just to mention a few, I am currently managing multiple experiments for my thesis project, mentoring a group of undergraduate students, and communicating my work to experts in the field and also the general public. These skills and experiences can be applied to any job in any sector. FUTURE taught me how to believe in myself and gain confidence in the power and flexibility of my doctoral training.
The sky's the limit
When I applied for graduate school, my goal was to become a principal investigator with my own lab doing cutting-edge research. That was the dream; or rather that was all I knew back then. It was not until my participation in the FUTURE program that I learned about other career opportunities for people with my skillset.
One career I encountered for the first time through the FUTURE Partner Network is a Medical Scientist Liaison (MSL). This is a healthcare consulting profession role that establishes and maintains a relationship between leading physicians and biotech companies. An MSL shares the information that a company gathered during the research and development process with physicians to provide them with a better understanding of how new products might benefit their patients. The MSL also solicits feedback about the products from the physicians so that the companies can work to further improve their inventions.
The FUTURE program not only introduced me to this career option, but also organized an informational interview with one of the MSLs in the FUTURE Partner Network who had herself graduated with a Ph.D. from UC Davis. The horizon seems wider now that I have seen the variety of fulfilling careers open to people with my training.
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A KEYC news anchor who implied that a bumbling broadcast was the result of her being sick and on medication has been arrested for suspicion of driving while intoxicated.
Annie Stensrud, 28, was arrested Wednesday. She was taken to the Sheriff's Department before being sent to a detoxification center in New Ulm, where she allegedly had a blood-alcohol concentration of .23 when she arrived about three hours after her arrest. The legal limit for driving in Minnesota is .08.
Stensrud's arrest came two weeks after a video of her verbally stumbling through a broadcast logged hundreds of thousands of hits on YouTube. Many viewers speculated Stensrud was intoxicated during the Sunday, Dec. 4, evening newscast because her eyes were blurry and her words were slurred and mixed up.
Talk show host David Letterman used the video to introduce a top 10 list titled "Top 10 Signs Your Local News Team is Drunk." Letterman's show is on CBS and KEYC is a CBS affiliate.
Denny Wahlstrom, KEYC general manager, later told a reporter Stensrud had not been drinking but was having a bad reaction to medication.
Wahlstrom didn't return a telephone call from The Free Press Thursday, but the station reported he would not be commenting on the "personnel matter" at this time.
It was around noon Wednesday when an anonymous caller reported an intoxicated person was leaving an apartment at 1608 Village Court. The caller said the woman was leaving in a green Honda Civic and provided a license plate number, a North Mankato police report said.
North Mankato Police Chief Chris Boyer, who was in an unmarked squad car, started following the Honda on Commerce Drive. It turned north on Lor Ray Drive, then east on the Highway 14 entrance ramp.
Boyer reported the car's right tires hit a curb before traveling down the ramp. After the car was on the highway, the driver was traveling completely in the shoulder lane for about 200 yards. The car swerved toward the center of the two lanes of eastbound traffic before tailgating a pickup truck. When Boyer turned his lights and sirens on, other vehicles pulled over, but the Honda kept going. A short time later a Nicollet County deputy arrived to take over and pulled the Honda over just before Mankato's Riverfront Drive exit.
A petition to have Stensrud released from the Brown County Evaluation Center in New Ulm was filed Thursday by Stensrud's attorney, Jim Fleming. The petition said she was brought to the Sheriff's Department at about 1 p.m. and arrived at the detoxification center at about 4 p.m.
Staff at the center initially said Stensrud would be kept there for between 36 and 72 hours. Although Stensrud had a blood-alcohol concentration of .23 when she arrived at the center, a staff member told Fleming she could be released because the alcohol was out of her system. Nicollet County District Court Judge Allison Krehbiel approved the petition, which said Stensrud would be driven home by her father.
Stensrud has not been on camera at KEYC since the Dec. 4 broadcast. A message Stensrud had on her KEYC Facebook page Monday said: "Thank you everybody for your words of support:) I hope to see you all as soon as possible!"


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So here is my report from spring break. I attended the Society for Photographic Education's national conference in New Orleans. The conference was nice - saw lots of friends and made a few new ones. The main attraction though was the city itself. I hadn't been to New Orleans for almost 20 years, so obviously much has changed.
The first thing I did after checking in at the hotel was hit the Mississippi River Walk
spe'rs out photographing the city. The person under the hood had a beautiful wooden 4x5 field camera.
Ode to Frank
Here are some classic New Orleans cemetery pics
Exploring the Garden District
These beaded necklaces were everywhere following a St. Patrick's Day parade
I had the good fortune to run into a former student from AACC. It was great to hear that she is still shooting and getting her photos published regularly for a local paper. Keep kicking ass Rachel!
After all that it was time to clear my head with a long drive along to the gulf coast and then up to Atlanta to see mom and pick up the girls. First stop Biloxi, MS
This is the city of Biloxi...For real, this is the whole effing town!
From the other direction
Oh, and they have a bank too
I guess this post would not be complete without at least one photo of the Gulf
An elevator (after John Ganis)
The town of Cottondale (somewhere in the panhandle near the border with Alabama)
What could be more American than firecrackers and limousines?
And finally Atlanta, where I met up with this dude for a breakfast of sweet potato pancakes!
Now it's back to work :|


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|Delivery time is always critical, if you need to be 100% sure I can ship an item immediately or within a specific time frame, please contact me first. I do not always know the inventory counts of each item and the inventory status indicators on each page are not determined in "real-time." They are updated based on a daily physical count of each specific item. If an item you order is unavailable I will notify you via email or phone. 100% refunds are IMMEDIATELY issued upon request of the customer.