text:
CheatBook-DataBase 2020 2020 [100% Working]
Ultracopier is free and open source software licensed under GPL3 that acts as a replacement for files copy dialogs.
Here I'll merely mention where to get them and what rank your characters are promoted to. Minotaurs wear Plate armor well, but cannot attain Grand Mastery. Therefore, it tends to bypass most enemies' magic resistance. A Dragon's combat performance is solely determined by a special Dragon skill.
- As far as I've been able to determine, all NPCs are of level 5, 15, 30 or
Governor of Poker - Gamekult.
Taking her into your party and keeping her there CheatBook-DattaBase almost a given. I intentionally did not use any Dragons, because I feel they take the CyeatBook-DataBase out of the game. CheatBook-DataBase 2020 2020 [100% can become Grand Master of the Staff and the Mace Mace being the better choice by farand also has loads of hit points, more even than Knights and Dragons.
This is particularly helpful because there is no spell which can replicate this apart from Fly, which does not work in dungeons. Final Working] More points in Axe and Armsmaster will help the Minotaur increase his combat skills even further.
Necromancers are weak in combat. All in all, Minotaurs are well rounded but do not have many especially important abilities. A Cleric can be done, but he's on the edge. The content hasn't changed that much; I have, however, changed my point of view on Vampires. As far as I've been able to determine, all NPCs are of level 5, 15, 30 or
Working] bonus is applied to all levels you've already gained as well as those you gain in the future. First Time Out. And don't forget Regenerate while you're at it. In addition to his combat Working], the CheatBook-DataBase 2020 2020 [100% has one more important skill: he is the only one who can become Grand Master at the Repair Item skill. Other important skills: Regeneration, Body Building and Meditation, all of which help the Dragon fight, but none as much as Woking] Dragon skill does. Desk Drive 2.1.2 Free Télécharger Cracked with License I stuck with my original Cleric, Frederick Talimere.
- The Troll is a powerful melee-oriented character who prefers brute strength rather than finesse.
- At high skill levels, this really starts to add up.
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- He does not disappoint in this game, either.
- Chain is an alternative, though it can't be trained up as far.
Install this: www.:
- Now that it's Grandmastered, a single point already boosts your reserves quite a bit.
- The best of them is Blazen Stormlance, with fully mastered skills and a rspectable level
- Done a full revision of the FAQ, adapting the layout to my new style and updating the text throughout.
- Cheats with a valuelist requires that you press at first the hotkey for the value and then the hotkey for the cheat itself!
- It is a combination 0220 two factors: its ability to allow Working] whole party to fly for an extended period of time, and the fact that its breath weapon always hits, does not cost any spell points, and does far more damage CheatBook-DataBase 2020 2020 [100% a regular arrow.
- Voulez-vous effacer les recherches récentes?
- His equipment is unimpressive, but he has a few useful spells.
- USB Raptor v0.
- Ventrinus, being fully built up, was more powerful than Devlin by a mile.
Last Updated: 09 June Hits: 55 Read more If one turns out to be hard, feel free to leave it alone until you've built another 5 levels or so. I'd probably have been able to get through that dungeon alive even if you couldn't avoid the lava by hugging the walls. Then again, late in the game you'll want to trade in your Necromancer for Ventrinus Taleshire anyway, and he's got them all Grandmastered right from the start. A Minotaur can be found early in the game.
Second priority: Armsmaster, Body Building and Regeneration, in that order. His equipment is unimpressive, but he has a few useful spells. AV Audio Sound Recorder 2.0.5 Registration Code Télécharger 2020 Finally, Minotaurs have limited skills in the arts of the Self Body, Mind and Spiritand can function as backup healers. Other important skills: Perhaps Identify Monster.
Fortnite fortnite season 8 woche 4 battle pass stern 8 51 how to get Woking] prime fortnite 0 Telecharger Pour fortnite skins real life hot Android Apk v buck generator tool Gratuitement. Both could do around damage points if they're lucky and the enemy isn't too resistant. FIFA 11 Cheats.
Other important skills: Perhaps Identify Monster. It's your call. You cannot complete the quest without him. 7-Data Recovery Free 3.4 Télécharger Cracked with License Cheats with a valuelist requires that you press at first the hotkey for the value and then the hotkey for the CheatBoom-DataBase itself! Last Updated: 16 June Hits: 33 Read more Build up this skill at a steady rate and you can open chests wherever you go without blowing up your party. You'll need to identify a lot in your travels. Grand Master skills of any 1[00% are only available to promoted characters, for example. Lan-Secure Wireless Protector Enterprise 5.2 Registration Key
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text:
β-Tricalcium phosphate (TCP) is an osteoinductive and resorbable material that offers superior biochemical activity for bone regeneration therapies. TCP nanofiber scaffolds are particularly promising owing to their high porosity and chemical composition that resemble the mineral phase of natural extracellular matrix. TCP nanofiber scaffolds were fabricated by electrospinning. The nanofiber morphology promoted unidirectional grain growth during the sintering stage due to lack of surrounding grains in the other two principal directions. The average fiber diameter after sintering was 100–125 nm, which is the smallest grain size ever reported for TCP.
|Original language
|Pages (from-to)
|Number of pages
|Materials letters
|Publication status
|Published - 2017
Fingerprint Dive into the research topics of 'β-Tricalcium phosphate nanofiber scaffolds with fine unidirectional grains'. Together they form a unique fingerprint.
Cite this
Cadafalch Gazquez, G., Chen, H., Moroni, L., Boukamp, B. A., & ten Elshof, J. E. (2017). β-Tricalcium phosphate nanofiber scaffolds with fine unidirectional grains. Materials letters, 208, 118-121. https://doi.org/10.1016/j.matlet.2017.05.038

subset: commoncrawl


text:
Herbs and Fruit
Dried herbs, fruits and flowers
Bright citrusy and floral notes
Reddish-orange jewel like liquor
Sweet, apple-like taste of chamomile with a citrus finish of orange and lemon.
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Beth S.
Verified Buyer5 star rating
Ginger flavor is a little
Review by Beth S. on 28 May 2020 review stating Ginger flavor is a little
Ginger flavor is a little lite for my taste. Would like it to be more intense.
Chamomile citrus is a delightful full flavor tea.
Chamomile citrus is a delightful full flavor tea.
On Mighty Leaf Chamomile Citrus - 100 pouches foil wrapped
John M.
Verified Buyer5 star rating
John Mathes order review
Review by John M. on 11 Jun 2019 review stating John Mathes order review
Everything I ordered arrived promptly and was as advertised. I had an issue with the small bag of Costa Rican coffee that was open in shipment and when I picked it up it spilled all over the table and floor. I called and I received a replacement bag of coffee and a sincere apology. I will continue to shop with your company.Thank You, John Mathes
On Mighty Leaf Chamomile Citrus - 100 pouches foil wrapped
David P.
Verified Buyer5 star rating
So glad I found 1st in coffee
Review by David P. on 26 Feb 2019 review stating So glad I found 1st in coffee
I was looking for tea as my local place stopped carrying my favorite brand. I found a great selection and reasonable prices here. This is my new favorite place for coffee and tea.
On Mighty Leaf Chamomile Citrus - 100 pouches foil wrapped
Tracie K.
Verified Buyer4 star rating
Great Decaf Tea
Review by Tracie K. on 21 May 2020 review stating Great Decaf Tea
I don't usually buy decaf anything but wanted to try something I could have later in the day. This tea looks as good as it tastes. Very Refreshing With a hint of citrus! I will definitely purchase it again.
On Mighty Leaf Chamomile Citrus - 100 pouches foil wrapped


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The Bumble Bee, Gloucester
Postal town: Gloucester
Pub TypeVintage Inns (Mitchells & Butlers)
Reviews (Current Rating Average: 4½ of 10) see review guidelines
Please Note: This review is over a year old.
Caroline Conibeer left this review about The Bumble Bee
Lovely looking pub inside and out, however the burgers ordered where burnt one was in 3 pieces and the relish non existent. The roast dinner claiming to have homemade yorkshire puds looked like they came from the value freezer section, the stuffing was a slimy lump and you could have broken a tooth on the pigs in blankets. Terrible considering you are paying around £13.00 for each meal. The drinks are pricey too such a shame.
On 22nd February 2016
- rating: 1
[User has posted 1 recommendations about 1 pubs]
Please Note: This review is over a year old.
Graham Coombs left this review about The Bumble Bee
Purpose-built Vintage Inn, as usual pretending to be a row of cottages, with standard interior divided into different areas with brickwork, reclaimed timber beams etc. Having said that, and despite emphasis on diners, it has a comfortable bar area and some reasonable ales including Butcombe Bitter and Taylor's Landlord. Cask Marque listed, and available of traditional ales featured on menu too - something to be commended for. Certainly worth visiting if eating out.
On 22nd November 2014
- rating: 8
[User has posted 2194 recommendations about 2145 pubs]


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Historical Advertisements
Something NEW under the HOOD!
Of the ACE is a new type automobile power plant. Read the complete story and description of this marvelous motor on page three.
The Greatest Advancement Made in Internal Combustion Engine Design in Recent Years
PASSE! "Indications are that the streamline, straight-side body is passing out." So stated a writer in a recent issue of a well-known motor journal.
What more fitting and proper than that a car, bearing the name ACE, and powered by a motor incorporating the greatest forward step in engine design, should set the style and fashion in new body designs.
In the mad race for quantity production, style and appearance were secondary considerations. For proof, observe the marked degree of sameness common to most cars. Style, always a big factor in the choice of a motor car, now influences to a greater degree than ever the selection of this or that car.
NEW! The ACE in four new, handsome body styles establishes a new standard in motor car fashions. There is an air of smartness and originality in their makeup that is as welcome as it is refreshing. Each of these four bodies portrays true grace and beauty in every line and curve and offers a pleasing change in appearance to the man and woman who have grown tired of, a style which has lost its attraction.
Compatible with its distinction and good taste in body improvement are mechanical features which lift the ACE from the ranks of the commonplace and identify it as a truly great and extraordinary motor vehicle.
Commerce SD-11 Roadbuilder
A fast, sturdy, long-lived, light dump truck built exactly to the contractor's own ideas. Continental S4—four-cylinder motor,4 1/4 borex4 1/2 stroke. Special bevel gear rear axle. Extra heavy semi-elliptic front and rear springs. Unit transmission. Double internal brakes. Radius rod drive. All steel automatic dump body of 1 1/3 yards capacity. Write for complete description of this popular job.
—the Commerce Relay Axle Drive
"It does pull out"—that's why the Commerce Relay Axle Drive Truck sells itself to the most skeptical dump truck operator. Here is a truck which will out-perform any other truck of similar capacity under any conditions—will deliver thirty per cent more work—with thirty per cent less operating expense.
The Commerce Relay Drive Axle embodies an entirely new method of applying power to the rear wheels of a motor truck. The power of the motor, the momentum, the weight of the load —all these forces are utilized in moving the rear wheels. In other words, the entire truck with the load gets under way first and aids in pulling out the rear wheels.
With such advantages, the Commerce Relay sells, and sells readily—strictly on a performance basis. Do you want your share of this business? Do you want to sell trucks—not prices? To make profits—not just sales? If you do, write or wire us today—find out if your territory is still open. Particulars of the Commerce franchise and descriptions of the complete Commerce line will be furnished you.
Export Dept.: 132 Nassau St., New York City
Cable: Commerstrux
MOTOR—Continental 6B, six-cylinder, vertical L-head, 3 3/41 bore × 51 stroke, 70 horsepower. Timken I-beam front axle. Commerce Relay Rear Axle. Multiple disc clutch. Transmission amidships, 4 speeds forward, 1 reverse. Gear ratio, 9.28 to 1. Frame, extra heavy, 7 1–161 section, 5 cross members, 2 brace rods. Front springs, special Commerce compound construction for easy riding. Rear springs, 541 long. 31 wide. Wheels and tires—front, steel spoke type with 36 × 6 pneumatic cords—rear, solid disc, 40 × 12 solids. Footbrake on transmission, emergency Internal expanding on rear wheels. High tension magneto. Electric head and tail lights, starting motor, generator and battery. Equipment —lighting and ignition switch, ammeter dash light, choke and oil gauge on instrument board. Horn button on steering wheel. Electric horn. Front bumper.
Ypsilanti Gleanings


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Based on several recommendations, I decided to call Edge Motorworks to service my E60 M5. Since this model has specific items/issues to look for/address, I only wanted to go to an EXPERT, and found my new service center for all my BMWs going forward. From the moment Angelo picked up the phone, I knew I was talking to an experienced shop..., he answered ALL of my questions (I took at least 20 mins) before booking my appointment. When I arrived, I was greeted by Angelo, he explained all the services they would perform and what they were going to check, and immediately, my car was in their service bay. Their lobby has large glass windows into their service bays, so you can watch your technician work on your car (awesome)! After my service was completed, Anthony went over all the findings and recommendations for the next service. Then, we walked out to the car and he showed me every item he discussed with me. Overall, I had a superior customer service experience! These guys are TOP NOTCH and I highly recommend them!!!
Thanks for taking a lot of time reviewing the needs for my car before alignment. If I couldn't do the work myself I would definitely have you do it but I'll be back for the alignment.
Awesome work, clean, fast, friendly and affordable. Highly recommended!!!
Excellent service & attention to detail here. Have had my car serviced by Anthony at Edge for almost eight years. Thank you for the special care that you take with my car.
The only place I go and trust with my Mini!
Anthony and Angelo are super knowledgeable and go the extra mile for their customers. They came in over Thanksgiving week-end to fix my truck so I could get back to Southern California. I highly recommend Edge Motorworks
Excellent service
My experience with the team at EDGE Motorworks could not be improved upon. They were flexible in accommodating me right away as my situation was relatively urgent (broken sunroof and huge rainstorms on their way). Once they had my car, they were prompt in delivering a detailed, clearly-explained assessment and were readily available to answer my questions. But the very best part is they fixed the roof for, literally, 2% of what Mini of Steven's Creek, just one day before, had told me it would cost. After the experience I had with Anthony and Angelo, I simply won't take my car anywhere else.
As always, great work! My car is running better than ever.
Very fast, very friendly and very professional service.....as usual! Thank you!


text:
The great dates of the Labrador
The following is a chronology of more than a hundred years of the history if Saint John's dogs, also known as Newfoundland Water dog, Black Water dog or what is currently known as Labrador Retriever.
The first dogs imported from Saint John arrive to England.
In the book "Instruction to young sportsmen" the first official mention of the Labrador Retriever appears.
The painter, Edward Landsser, left the first painted trace of the Labrador at the time. The picture was called "Cora, una femmelle labrador". It is also interesting that the female had White spots, which were, later on, taken out from the selection
The kennels specialized on Labrador is no longer rare on the other side of the channel, where the black dogs were used to get the pray, which are frequently found in the breed of the Game Keepers.
The quarantine (six months in which imported dogs are no permitted) is established in Great Britain.
Two yellow puppies appeared in a litter from Buccleunch's breeding house and they were born from black parents.
The first yellow Labrador, Ben of Hyde, which was born in the breeding house Major c.j Radclyffe is registered officially in the United Kingdom.
The Kennel Club, officially, recognized the Labrador on the 7th of July and incorporates it officially to the nomenclature of the sporting group on November 3rd.
In January, the Labrador, finally, obtains its own classes of exposition, different to the ones of the rest of the Retrievers.
The Retriever Club in France opened.
More than 200 puppies are registered by the Kennel Club.
The birth of the dean of the breed clubs.The Labrador Retriever Club, thanks to two of the forerunner leaders, the Countess Lady Loma Howe ( who would be famous because of her election of black Labradors under the affix Banchory) and Lord Knutsford, whose Munden affix is present in the genes of all the Labradors nowadays.
Almost 1,000 puppies were born in English breeding houses.
The honorable A. Holland Hibbert writes an article in which he states the different items of the standard of 1916.
Establishment of the Yellow Labrador Club Retriever.
Creation of The Labrador Retreiver Club Incorporation in EEUU.
1932-1933: On two consecutive years, the black Labrador, champion Bramshow Bob won the supreme best in Show en the Crufts exposition. .
The Labrador is again benefited by the great interest show on the other side of the atlantic by getting the first North American seal impressed with its figure ( the represented dog was a black Labrador called King Buck).
The English breeders are in shock due to the murder of the excellent breeder Joan Macan who worked for over more than 50 years for the well-being of the Labrador.
The Labrador was at the top of the favorite breeds by the British with 26,392 registrations in the origin books of the Kennel Club.
The Labrador gets the first place in the oficial American Rank. This record is maintained until today. .
Record year for the English breeding; 36,000 subscriptions that year.
The world breeders find out about the news of Gwen Broadley's disappearance, to whom some people assume him as the father of Labrador's modern selection regarding Sandyland's affix. Fortunately, the selection continues under the coordination of Erika Hayes, a famous Handler of breeding champions.
The Labrador Retriever Club celebrates a hundred years of the breed in the marvelous Belvoir Castle, in which nearly 1,000 Labradors were exposed for two days.


text:
Explanation of SinQ Signature
SinQ Signature Goa
One of the 3 star hotels in the Goa which is located Behind Navtara Restaurant, Naika Vaddo, Calangute, Bardez Goa 403516 Goa Goa India, this hotel was built in 2016 and most recently renovated in , offering a variety of luxurious amenities with comfort and safety for its guests
SinQ Signature is perfectly located for both business and leisure guests in Goa. Both business travelers and tourists can enjoy the hotel's facilities and services. Take advantage of the hotel's free Wi-Fi in all rooms, restaurant, elevator, poolside bar, free breakfast. All rooms are designed and decorated to make guests feel right at home, and some rooms come with television LCD/plasma screen, towels, internet access – wireless, air conditioning, mini bar. To enhance guests' stay, the hotel offers recreational facilities such as outdoor pool. For reliable service and professional staff, SinQ Signature caters to your needs.
If you visit the city Goa Goa, India. For personal, business or leisure visits with family. You can choose a SinQ Signature as an alternative for your stay and spend time.with 3-star facilities enjoy the convenience of service and friendliness of the staff.
This hotel open in public 2016 with 41 room in 4 floors.
You can check in 1:00 PM and check out 10:00 AM
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The following is a photo of the building, rooms and decoration of the SinQ Signature Goa as your reference before visiting this hotel.
Details location SinQ Signature in map
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text:
Over the years, many things have changed, but the basic concern of protection of your family, home and assets has not. In today's digital age we are presented with many high-tech surveillance tools that can simplify your precautionary efforts, resulting in more efficient safety measures. The below technologies are changing the game when it comes to keeping you safe and giving you peace of mind.
Fog Security
This residential and commercial security appliance sends out a dense stream of fog when an intruder is detected. While the fog is safe to breathe in, it will instantaneously impair the vision of an unwelcome visitor, making it hard for the burglar to see into your home or office. This security measure stops any number of intruders and is easy to relocate and leaves no residue in your home or office.
Retinal Scan Lock
If you feel you need to up the security around your house, or even certain areas of your home you can invest in a retinal scan lock. This deadbolt device identifies the eye composition of those who are allowed access into the area and bar those who do not match the list of authorized personnel. You can also buy a smaller version of the retinal scanner to use with your computer or other sensitive devices.
Wireless Camera and Remote Viewing
One of the best things about having a home video surveillance system is being able to watch back what happened within or outside of your house while you were gone. With today's technology, many wireless monitoring systems allows you to watch real-time footage of your home's perimeter from a connected smart phone, tablet or computer. When suspicious activity triggers an alarm, you are immediately notified and can isolate the footage to show law enforcement.
Smart Timed Lighting
The advanced technology in LED bulbs is able to keep your home safe from intruders. These new bulbs are able to learn at which times you are turning them on and off. After an adjustment period, the lights begin to illuminate on their own. Because burglars are drawn to dark empty houses, the bulbs continue with your daily pattern making it look like you are home even when you are gone for an extended amount of time. You can even program them to light up in a certain order if someone rings the doorbell so it will appear that you are moving from your bedroom to the door.
Keyless Connected Lock
Sometimes regular key locks are not enough, if you'd like to take your security one step further, you can install a pin-operated mechanism that secures your doors without the need of a key. To disarm the lock, press in the code (which is changed every 24 hours) or tap your smartphone against the sensor. The lock also has a tamper alarm and lock-out chip if an invalid code is entered more than five times.
About the Author
Sydny Shepard is the Executive Editor of Campus Security & Life Safety.
• Enhancing the Perimeter
• Avoiding Danger with Secure Data Storage
• Making Cities Smarter
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• A Virus on the Move


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Jason Carr
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Mr. RetroLust
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Showing content with the highest reputation on 11/15/2019 in all areas
4 pointsBeta 4 is out now with the following: Improvement: LaunchBox and Big Box now use improved processes for media downloads (threaded downloads). This should signficantly speed up downloads from the LaunchBox Games Database, especially. Improvement: In Big Box you can now individually hide view types while locked instead of all or none New "Games Missing Media" filters now have items for videos and manuals as well Fixed: "Scan for Removed ROMs" now removes additional apps that are missing as well Planning for this to be the last beta release with new stuff before the official release, which hopefully will go out early next week. Any testing you can do would be appreciated.
3 points
Version 1.0.3
461 downloadsMassive thanks goes to @y2guru for the COMMUNITY Theme Creator for BigBox. Also thanks to @Grila for some of the code snippets I've used. _____________________________ INTRODUCTION I know there's been arcade machine based themes before, The reason I wanted to make this one was firstly to try out some of the new features that were added to the theme editor, and secondly I've always wanted to see the side of the cabinet with the artwork. There is a known issue with the theme and for that reason it's best used at 16:9 aspect ratio. _____________________________ INSTALLATION Download the zip file and unblock it (right click the zip file, goto "Properties" then at the bottom put a tick in the "Unblock" box, hit ok when done) then extract the folder to --\Launchbox\Themes\
3 points
3 pointsJust uploaded version 0.27 to the Play Store, so it should be available soon. I'm hoping this release fixes the app killing issues I described above for at least some people, but I'm fairly certain it won't fix it for everyone. Still, if you were experiencing issues with the new import process closing to the desktop, please give the new version a test and let me know how it goes. I did some brainstorming with @CBeatt13 (C-Beats as he apparently likes to go by these days), and we came up with some more optimization I can do to try and prevent the app kills further, but that will take quite a bit more development effort, so I'm hoping that these quick fixes at least help in the mean time. All in all, I have no idea if we'll ever be able to eliminate the app kills completely, but I'm certainly hoping so.
2 pointsSure, I can add that to the list.
2 pointsRolling Thunder 2 rthun2.zip
1 point===========Mr. RetroLust's - Mame 4K - Lights Out - Realistic Bezels=========== Realistic bezels in 3840x2160 resolution for Mame. My goal is to make bezels for around 1300 Mame games I have in my collection. I make these bezels to focus on the gameplay not the artwork (it should compliment the gameplay), this means large game screens and instructions fully visible where possible. In this thread I upload the newest bezels individually, if you like you can download the most current versions here or you can wait till I reach around 200 new bezels, that's when I upload a new pack which you can download in the link below. I started off this thread with random titles, later on I realized the best way to work would be alphabetically Note: The first pack includes Neo Geo, Cps1, Cps2 & Cps3 as well, these are conversions of the RetroArch bezels I made before, these haven't been uploaded in this thread. =================================== Here's my first Mame 4K bezel shdancer.zip
1 point
Version 1.3
470 downloadsNew Version 1.3 Added a visual playtime setter/editor New Version 1.2 Fixed another string error that would sometimes cause the playtime to not record. Thanks @TheNewClassics. Everything should work now but please don't hesitate to let me know if any other problems arise. New Version 1.1 Please update to the new version. I caught a string error that would prevent any playtime from going over 23 hours. The new version will keep all your game's previous playtime intact. Also, you can now reset a game's playtime in LB from the selected games right click menu (@Krakerman). Drop the .dll in your LaunchBox\Plugins directory and start tracking how long you play your games. The playtime is recorded as a custom field so it is visible in LaunchBox on the game details bar and in BigBox in the game details. See the screenshots for reference. Known Issues: Per the plugin API (http://pluginapi.launchbox-app.com/html/a40a286d-83c6-e179-940c-7e4166d567fe.htm) this may not function correctly with all platforms (ie. Steam) but I have tested it with RetroArch, Dolphin, and PCSX2 without problems.
1 point
Version 1.0.0
191 downloadsNeo Geo v2 4K - Lights Out - Realistic Retroarch Bezels This is an upgrade to my previous Neo Geo bezels where I only used top or bottom strips, in this version I used as much instruction artwork from the mvs kits as I could possibly find including side art. Contains restored and translated artwork as well. This is part of the "Lights Out - Realistic Retroarch Bezels" series: https://forums.launchbox-app.com/files/file/1950-mr-retrolusts-lights-off-retroarch-bezels/ If you like these in Mame format go to: Mame 4K - Lights Out - Realistic Bezels ========================================== FEATURES - All in 3840x2160 pixels for high detail - 152 unique bezels ========================================== INSTALLATION The following steps are for users of 3840x2160 displays only. This setup will save you countless hours adjusting them yourself, but be sure not to rename any files or folders and follow below instructions. IMPORTANT: If you use another resolution you'll have to manually adjust the position and size of the game screen yourself. 1. Place the contents in the folder "RetroArch/config/FB Alpha 2012 Neo Geo" to the folder of the core that you use, as you can see I use the FB Alpha 2012 Neo Geo core. 2. Within this folder rename the following config file "SNK - Neo Geo" to the name of the folder where your NeoGeo games are stored. This file will automatically give all the NeoGeo games without artwork the generic bezel. 3. Place the contents from "RetroArch/overlays/_MR.RETROLUST/NeoGeov2" to it's like named structure within RetroArch. Done & Enjoy! \m/ ========================================== CREDITS Mr.DO: http://mrdo.mameworld.info/mame_artwork_ingame.php NeoGeosoft: http://www.neogeosoft.com
1 pointHello, I was writing just to inform that I have finished installing all my steam programs and games and everything is working very well, I thank you very much for your help with this topic, thank you and until next time
1 pointArcade View File Massive thanks goes to @y2guru for the COMMUNITY Theme Creator for BigBox. Also thanks to @Grila for some of the code snippets I've used. _____________________________ INTRODUCTION I know there's been arcade machine based themes before, The reason I wanted to make this one was firstly to try out some of the new features that were added to the theme editor, and secondly I've always wanted to see the side of the cabinet with the artwork. There is a known issue with the theme and for that reason it's best used at 16:9 aspect ratio. _____________________________ INSTALLATION Download the zip file and unblock it (right click the zip file, goto "Properties" then at the bottom put a tick in the "Unblock" box, hit ok when done) then extract the folder to --\Launchbox\Themes\ Submitter Rincewind Submitted 11/15/2019 Category Big Box Custom Themes
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1 pointI would upload these to the database, but there is no option to mass upload images? I would have to upload them one at a time? lol. I dont have that kind of OCD. TBH I wish I had access to the launchbox database and manually add/remove things. It's getting to be a bit of a mess with duplicate or wrong images. Even some of the info metadata is wrong on most of these titles. It could be worse I suppose. Sorry I didnt have this collection in launchbox naming standards. But others will have different names for them in their own collections anyway. At least the no-intro naming scheme is standard as you can get.
1 pointYeah but he was asking if they run in MAME by itself. If they dont run in just MAME they will never run from Launchbox either.
1 pointThere's an explanation how to do it in the other thread. i need to investigate this further. I have to go now, but I'll try again tomorrow. It seems like I'm close =D
1 pointSecond this,
1 pointThanks, I think you also need the "raster.ini" and "vector.ini" files from /ini/presets in your Mame folder. If it's not too much of a bother, that would be awesome if you shared them. I like how your settings aren't overpowering. The scanlines look "right" in my 40-something brain as to what arcade monitors looked like back in the day.
1 pointAwesome work, thanks so much for this project. Just curious, what shader are you using in those pics?
1 pointFollowing the update the import process is now working on my shield tv. Great work thanks
1 pointRolling Thunder rthunder.zip
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1 pointi think the idea is just in case it gets left on accidentally or i imagined maybe .txt or .cfg file that you can manually set it if you already played a ton of the game. just idea. cant wait to try this. i was one of the people requesting this. thanks so much man EDIT** I just realized you can edit it in the custom fields. which makes this the perfect plugin. you are the man.
1 pointIf you go to the \Launchbox\Data\Playlist folder do you see an All.xml file? If so, close Launchbox first, then remove that All.xml from the Playlists folder. Do not delete it just move it out of your Launchbox folder just in case. Then reopen Launchbox and see if there is no longer 2 "All" listings.
1 pointI won't say no, but it's a little out of the scope of this project. I'll keep it in mind though. It is possible. Under the LaunchBox\Plugins\PlaytimeTracker folder there will be a bunch of plain .txt files that store the actual timespan. The problem is, is that they are named by the game's id from your LaunchBox\Data\Platforms xml file. So in the plugin's current state, you'd have to find the id from the data xml from the corresponding platform, then edit the text file from the plugin directory with the same id with the same format as in the text file (hours:minutes:seconds, example 00:00:05.8454237) I do have an update that I'll push soon that will make this easier, but it's not entirely ready yet.
1 pointI just posted V1.1.1 of my Windows bezel installer app. Changes include PS3 Retroarch output support as well as a 2nd bezel design type. We are calling the original and continued bezels 'themed' and the new type 'system art'. You will need to pull an update under option 1 to get the new listings. Also make sure you select which bezel type to download in Preferences. Below are a few examples of the new type (only 13 sets as of this post, but more are coming). Please let me know if you run in to any problems/issues.
1 pointYou're welcome. It took my a while to get my set up just right, hopefully this will save you $$$ for dongles and accessories as well as hours worth of struggling like I did.
1 pointI submitted the error to MameTesters and a fix has already been submitted and checked. So hopefully next MAME version should be fixed. Update: Fix is included in MAME 0.216. Looks like 0.216 introduced a bug (crash) in twincobr though. 🙁
1 pointIf anyone's interested to update their files I've decided to take the time and redo them as a lot of games have been added. I've also added ST-V, Model 2 and Model 3. Should you update with these? If your Mame set is relatively new then I guess yes! Hope this will save you some time they took quite some of my yesterday's night to do hehe! 0.215 version https://github.com/Emulga/Mame-Rom-Extractor/releases/tag/0.215 Usage https://github.com/Emulga/Mame-Rom-Extractor/wiki/Usage
1 pointHere is a realistic Arcade overlay for the game Space Invaders for use on Retroarch. This overlay is coming soon on my Arcade Retroarch Pack. Stay tuned!
1 pointTycho's DOS VHS Startup View File I just felt like making another DOS-centric startup video, but I got a little fancy with it. Runtime: 64 seconds Resolution: 1920x1080 Framerate: 30fps Filesize: 40Mb Music: Scandroid - The Force Theme (Star Wars Cover) If you like it, let me know! If you hate it, let me know! Submitter tycho1974 Submitted 08/14/2019 Category Big Box Startup Videos
1 pointThis is a continuation of my previous tutorial on adding my realistic arcade bezels to Retroarch
1 point
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1 pointAs some of you may know Dolphin is now like RA using the QT based frontend, and this doesn't currently work with RocketLauncher untill now. And with the QT Frontend very nearly feature complete they will stop work on the WX based exe (DolphinWX.exe). Unpack this module to your RocketLauncher Modules folder. You have 2 options with this module, 1. Use the QT Based Frontend all the time, with a method to use the old WX based Dolphin or Ishiiruka's, 2. Use WX solely until such time you wish to swap to the QT branch (if you use this method then you emulator must be the DolphinWX.exe or Ishiiruka's Dolphin.exe Fire up RL, go to your Emulators and set you GameCube/Wii/WiiWare emulator to the Dolphin.exe (All new versions of Dolphin have the Dolphin.exe as the QT version), and change the Module to the new Dolphin QT Based you just added. Now select your GameCube/Wii/WiiWare on the left side, and then go to Modules Tab highlight the Dolphin QT Beta and hit the Edit Global Settings button. If you are using the WX version as your main exe then on the settings page you MUST set 'Enable_WX_Mode' to True, leave this at default if using the new normal Dolphin.exe If you want to use say Ishiiruka or even an older version of dolphin, you can set this via a Game Only basis. Go to the Module and edit it again, and go to the Rom Settings tab,here you need to do 3 things. 1. Hit the Red+ and select the game you wish to use a different emulator version for. 2. Set the 'EnableLegacy' to True. 3. Set the LegacyExePath, select the exe you wish to use for this game (Note must be a WX Based exe, Ishiiruka's at the current time is only WX). While this seems a lot, it allows you to have a bit of control to what dolphin you want to use, and allows usage of the new QT version. If you get any problems with this, or find a bug, please do not hesitate to leave a message, and try to include as much information as you can on what/how its doing. Dolphin QT Beta v220.127.116.11z


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Oropouche East Member of Parliament, Dr Roodal Moonilal will face Parliament's Committee of Privileges on allegations he made regarding Prime Minister Dr Keith Rowley surrounding A&V Oil and...
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The Rundown, Season 8, Episode 16
A Scarborough mechanic was arrested and a quantity of marijuana seized, by officers of the Tobago Divisional Task Force during an anti-crime exercise, conducted at the Scarborough Port, over the...
The Met Office has issued an Adverse Weather alert for the period Wednesday October 17 from 10 am to Friday October 19 at 8 pm.
The Met Office says the alert is due to an active Inter-...
Feeling the pinch from the increased cost of Super gasoline, scores of motorists are flocking to the Carousel Service Station in San Fernando to fill their tanks with Regular gasoline...
Police Commissioner Gary Griffith says he is in the process of treating with the thousands of applications for Firearm User's Licenses (FUL), that he met upon his assumption of office.
Firefighters are now battling a house fire on Gallus Street in Woodbrook. Police are on the scene and are directing commuters away from Gallus Street. We will bring you more on this later.
A fire at the garbage dump at the Ministry of Education has forced the evacuation of the building. Members of the Fire Services have responded and have brought the blaze under control.
A Cumuto man, who was arrested during an Operation Strike Back exercise, is expected to appear before the Sangre Grande Magistrates' Court today, charged with the murder of David King.
The Ministry of the Attorney General and Legal Affairs says that Minister in the Ministry of the Attorney General and Legal Affairs, Fitzgerald Hinds will act as the Attorney General and Minister...
A Valencia man was arrested and a pistol and a quantity of ammunition seized, by officers of the Eastern Division Task Force, during an anti-crime exercise conducted in the Valencia district last ...


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Diagnosis of Rocky Mountain spotted fever was made as early as the fourth day of febrile illness in rhesus monkeys (Macaca mulatta), with a monocyte culture technique that is easily amenable to use in humans. Rickettsia rickettsii were identified by direct immunofluorescent and Gimenez staining of cultures of circulating monocytes from four experimentally infected monkeys, even in the presence of a mild or inapparent disease in three. Levels of rickettsemia were estimated by the plaque-assay technique, and specific antibody titers were determined by complement fixation.
DeShazo RD, Boyce JR, Osterman JV, Stephenson EH. Early Diagnosis of Rocky Mountain Spotted Fever: Use of Primary Monocyte Culture Technique. JAMA. 1976;235(13):1353–1355. doi:10.1001/jama.1976.03260390039026
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Bravo! M&S launch a bra that blends in with your skin tone to be invisible when you dress
Every woman knows the feeling that comes with catching sight of yourself in the mirror and realising your white bra is showing through your top.
But it could become a thing of the past with the introduction of an 'invisible' bra from M&S designed to blend perfectly with any woman's skin.
On display: Models Joelle Kayembe, Ana Tanalia, Sarah Wiffen and Catherine Thomas outside M&S in Marble Arch, central London
While other attempts at making 'nude' underwear have tended to take a one-colour-fits-all approach, the £18 Nearly Naked bra comes in four shades to match a range of skin tones.
Researchers at M&S scanned the skin colour of more than 1,000 customers using a spectrophotometer – a machine which determines the individual shades that make up the final colour of the scanned object.
Shade of pale: The flesh-coloured underwear comes in four shades to closely match customers' skin tone
The results were compared with ethnicity data from the Office for National Statistics to select colours that were an exact match for human skin.
The bra is available in sizes 32A to 40D. The range also includes matching briefs for £8.
Disappearing act: The underwear, £18 for bra and £8 for briefs, is designed to appear invisible under clothes
Soozie Jenkinson, head of lingerie design for M&S, said: 'Women are recognising the need to wear a neutral-coloured bra which complements their own skin tone and can create a "disappearing act" under clothes.'
Paschal Little, head of lingerie technology for the chain, added: 'By using revolutionary new techniques we have been able to produce a wonderful product which is not only a great fitting lingerie range but also one which will suit every woman in the nation.'
Sunnier climes: Twiggy, Dannii Minogue, VV Brown, Lisa Snowdon and Ana Beatrix Barros film the new Marks & Spencer advert in Miami Beach
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3.0.89 · DealerApp Vantage
May 15, 2019 (1 year ago)
3.0.89 · DealerApp Vantage
May 15, 2019 (1 year ago)
"The #1 Certified Dealer in the World!"
|3.0.89 (23189)
|May 15, 2019 (1 year ago)
|DealerApp Vantage
|Apps, Business
At Paragon Acura, we believe our success is due to how we treat out guests; Paragon is a quality oriented, full service automotive dealership. We are "The #1 Certified Acura Dealer in the World," because we are committed to owner loyalty and providing the resources to completely satisfy our guests' needs.
Now, we are proud to bring you our very own DealerApp! Some of the things our app can do for you are:
- Search Vehicle inventory using an Intuitive, fast, and easy to use system specifically designed for the app.
- Postboard messages and Notifications to alert you of specials, coupons, and announcements. Notifications are catered to your individual needs and can include images, videos, and attachments.
- Keep track of your vehicles in "My Garage". Add a photo of your vehicle and track things like: VIN, Year, Make, Model, License Plate, Oil Type, Tire Size, Date Purchased, Price Paid, Initial Mileage, Insurance Co., Policy No., and add all the extra notes you want.
- Service History is also available for each vehicle in "My Garage", see pending service appointments, add them to your calendar, and mark them as completed.
- The "Toolkit" contains super useful tools for you to use every day. The Toolkit can include things like:
Roadside Assistance
One-touch Service Scheduling
Local gas prices
Parking Assistant with GPS locator and meter timer
and more.
This section gets updated regularly and new features are always added.
- Stay up to date with everything going on in our OWNERS RESOURCES section.
- Includes all of our Social Media posts which you can share with friends and family.
- Get the latest news, events, and info from the manufacturer.
- Plus much more that can be included like our customer Reviews, Videos and Tutorials, and Owners Manuals
In addition, all the standard Dealership App features are also here like: Call and email each department, get directions, view operating hours, get quotes on vehicles, order parts, etc etc…
Powered by DealerApp
Email: firstname.lastname@example.com
Turn on update notification
GPlay97 · Auto & Vehicles
4.3 ★ 10,000+
HRTuning.com · Tools
4.5 ★ 100,000+
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Google LLC · Tools
5.0 ★ 5,000,000,000+
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4.4 ★ 100,000,000+
News, Tutorials, Tips & Tools
See more


text:
2019 Chevrolet Malibu
$22,960 • New
Asking Price
Ext. Color
Mosaic Black Metallic
Stock Number
Odometer Reading
4 Cylinder
Int. Color
Jet Black
Front Wheel Drive
Installed Options
6-Way Manual Driver Seat Adjuster
6-Way Manual Front Passenger Seat Adjuster
Cargo Net
Convenience Package 1
Engine: 1.5L Turbo DOHC 4-Cylinder DI w/VVT
Front & Rear All-Weather Floor Liners
Front Bucket Seats
Preferred Equipment Group 1LS
Radio: Chevrolet Infotainment 3 System
Remote Start Kit
Tires: P205/65R16 All-Season Blackwall
Transmission: Continuously Variable
Wheel Locks
Wheels: 16' Aluminum
Seller's Comments
LS- Remote Start � Back-up Camera � All-Weather Floor Liners � 4G LTE Wifi Hotspot Capable � Apple Carplay/ Android Auto � 7' Touchscreen � Bluetooth/ MP3/ USB Port Wilson-Niblett Motors has been proud to serve York Region for almost six decades! We want to thank you, our loyal customers, for making us the success we are today! If you're part of our 'family', you already know about our commitment to outstanding customer service and satisfaction and to being your dealership of choice in the region. Want to shop from the comfort of your own home? We offer our vehicle buying experience online including personalized virtual walk-arounds, payments and financing over the phone and at-home deliveries. Our Showroom is now open by appointment only. Call 1-866-508-9030 and one of our knowledgeable product specialists will be happy to assist you. Wilson Niblett price is a cash price and is inclusive of General Motors cash credits of $4,400 and a Wilson Niblett cash credit of $1,000.00. Pricing may not be compatible with finance and lease offers. All prices are plus applicable taxes and licensing. Offers valid until June 30, 2020. Vehicle may not be exactly as pictured.View More
10675 Yonge St
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text:
Bayer recently launched its first Facebook ad. The ad also happens to be the first time Facebook has allowed a company to put important safety information (ISI) in a scrolling format, something that pharmaceutical companies have long been able to do in banner ads.
In addition, the social media giant is also enabling drug companies to block comments on pages that are used to market their own products, potentially minimizing the risks associated with reporting adverse events that have not been thoroughly vetted.
Build a Better Customer Experience with AEM on Microsoft Azure
Businesses leveraging the two technologies together would now be able to harness their data for critical insights and predictions, connect customer touchpoints across their business, and drive brand loyalty and growth.
Facebook also continues to beef up their community pages by allowing pharmaceutical companies to sponsor them.
Advertising on Facebook has been a boon for companies like Johnson and Johnson, which has been using the platform for years to promote many of its consumer products. However, pharmaceutical companies have largely stayed away from Facebook because of the repercussions they could face from the FDA. In 2014, the FDA issued draft guidance, but has yet to provide any firm rules for companies to follow.


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6位当地人推荐 ·
There was a nice exhibition about renaissance of architecture. It is located quite near from Meguro river, peaceful place. I like the feeling there.
A lot of art museums are in Tokyo and hesitate though I go, but are the most big art museum in Meguro. I enjoy art in an art museum of Meguro and am a place to be enough for because I can go to drink
"Dating from the early Showa period in the 1920s, this Japanese building shows signs of influence from Western architecture. Inside, the spacious exhibition hall seems to stretch on endlessly, whetting one's appetite for its treasures. The displays have a distinctive Showa flavor—a glimpse into an interesting era of Japan's development. Right after opening or before closing, there are fewer people, so you can have a relaxing tour. At those times, it's quiet enough to hear the wooden floor creak under your feet, which adds to the retro ambience."
- 6位当地人推荐
"Historic Japanese traditional arts theater. Noh is a classic stage drama based on historical myths and stories."
- 5位当地人推荐
"near by Isetan Department Store, famous traditional fried-curry restaurant "
- 1位当地人推荐
"For those who speak / read Japanese and are interested in modern Japanese literature this small museum is a treasure house."
- 3位当地人推荐


text: Results 1 - 10 of 14 Display 10 25 50 75 100 per page Sort by: Relevance Date Posted next Marketing Management Learnership Based in CPT Cape Town Advertising, Marketing, Academic R65 000.00 Per Month Contract Marketing Management Learnership - NQF level 4 Cape Town Salary: from R6500.00 per month (1 year Learnership, 4 months classroom training) Start date: 01 October 2020 Applications Close: 30 July 2020 Key Skills Required: Basic understanding of... See more. Posted by Isilumko Staffing (CPT) on Thursday, July 9, 2020 59 Days left Add to shortlist Email Graphic Designer - Bloemfontein Bloemfontein Advertising, Design Services, Marketing R15 000.00 Per Month (Negotiable) Permanent Overall designing and creating of marketing content to drive sales/revenue and convey a certain message to consumer. Keeping budget, time and production constraints in mind Preparing and presenting marketing content before deciding on a final design... See more. Posted by Workersweb on Wednesday, July 8, 2020 57 Days left Add to shortlist Email Sales Representative Benoni Advertising, Call Centre, Sales Market Related Permanent ob Summary Promote and sell Affinity Health products. Key Performance Areas/Key Responsible Areas Achieve quality standard sales. Achieve departmental performance target. Advise clients on the most suitable policies. See more. Posted by National Risk Managers ( Affinity Health) 56 Days left Add to shortlist Email Receive job alerts for Jobs in South Africa via email Create Job Alert Social Media Marketer Germiston Advertising, FMCG, E-Commerce R12 000.00 Per Month Permanent Looking for a young energetic person to manage and oversee our Ecommerce sales platform. Shopify Ecommerce platform. Social media marketing. See more. Posted by Boksburg & Southern Superspar on Tuesday, July 7, 2020 56 Days left Add to shortlist Email Media Sales Executives Cape Town Advertising, Media, Sales R33 333.00 - R41 667.00 Per Month Permanent We are looking for highly ambitious sales people to join our rapidly expanding company. The right candidate needs to be available to start immediately! Here at FOUR Magazine/AP Media Group, we work with some of the biggest brands in the luxury market.... See more. Posted by FOUR Magazine/AP Media Group on Thursday, June 25, 2020 45 Days left Add to shortlist Email Video Presenter Randburg Advertising R10 000.00 - R15 000.00 Per Month Permanent Looking for a professional, well groomed, imaginative and fun-loving on-camera presenter to join our Gauteng team of videographers and content developers for the motor industry. A versatile personality is a must, along with a unique ability to 'think ... See more. Posted by Surf4 (PTY) LTD on Monday, June 15, 2020 30 Days left Add to shortlist Email Sales Affiliate Randburg Advertising, Sales, Health Fitness & Beauty R5 000.00 - R25 000.00 Per Month Permanent MyHealth365 is looking for vibrant, energetic Sales affiliates to join our team. At My Health365 you will be required to sell products directly to the consumers, giving yourself the opportunity to build a loyal client base and earn fantastic commissi... See more. Posted by Myhealth365 on Tuesday, June 9, 2020 29 Days left Add to shortlist Email Digital Marketing Specialist Hillcrest Advertising, FMCG, Marketing Market Related Permanent Plan and execute all digital marketing, including SEO/SEM, marketing database, email, social media and display advertising campaigns Design, build and maintain our social media presence Video Editing Manage electronic newsletters Measure and repor... See more. Posted by Oxford Freshmarket 24 Days left Add to shortlist Email financial manager Bloemfontein Advertising, Finance, Management R12 000.00 - R18 000.00 Per Month Permanent Bestuurspos: Voltooide klerkskap + SAIPA / SAICA geregistreerd vereiste. Pakket na gelang van ondervinding. (R12,000 – R18,000, Pensioen + Bonus See more. Posted by Rectitude Recruit on Sunday, May 31, 2020 19 Days left Add to shortlist Email call centre agent Bloemfontein Admin, Advertising, Call Centre R5 000.00 - R7 500.00 Per Month Permanent call centre agent Bfn Main Job Tasks and Responsibilities • contact businesses • follow up on initial contacts • complete records of telephonic interactions, orders and accounts • answer calls and respond to emails • handle cu... See more. Posted by Rectitude Recruit on Sunday, May 31, 2020 19 Days left Add to shortlist Email 1 2 Results 1 - 10 of 14


text:
Photography is equal parts science and art, with skills and vision playing crucial roles in the final results. Whether you are content with an amateur's level of photographic skills or you aspire to be the next Ansel Adams, these tips will take you one step further in understanding the process.
If you are taking pictures in the sun during the spring or summer, make sure to turn the flash on. Failing to put the flash on your camera can result in a bad glare, which can taint your photos. Once you turn the flash on, you can take pictures as you usually would.
A great photography tip that can help you out is to be realistic about your work. You can't expect to be a creative genius at all times. Art has a lot of ups and downs and if you're expecting to always be on top, you'll become very discouraged.
Don't stay inside when the weather is bad. Although it's natural to think a sunny day is the best time to grab the camera, overcast and rainy days provide an opportunity to get shots that would be hard to get at any other time. These weather conditions can give shots that would look neutral or cheery on a sunny day a dark and foreboding tone.
The number one lighting to avoid in photography is the use of your built in camera flash. Using the flash setting in your camera actually creates the dreaded red eyes and makes your subjects appear featureless shadow blobs. Only use this setting in the case of an emergency if you are left with no other choice.
The key to taking good photographs is to always remember that lighting is the most important thing. Think about lighting all the time. It does not matter what the source of the lighting is, but it is the elemental part of any photograph. Use the sun, a streetlight, a spotlight or even the computer screen to capture any light and make a great photograph.
Tripods are great pieces of photography equipment, but not everyone has one or can afford one for their shots. So, what can you do in the meantime to make sure that you have steady, sharp shots of your subject? Try leaning against something solid so that you can steady your hands and the camera.
Play with lens distortion. Most photographs use portrait lenses or zoom lenses to focus on an object, and use a wide-angle lens for landscapes and such. By using a lens for a different use than its intended one, you will get a very original photograph. Do not let this become your style: learn when you can use an original lens.
When learning photography, at some point you will need to have some kind of professional instruction. Self-teaching can only get you so far. If you are not taking a class on photography, try getting involved in the photography community. Talk to and ask professionals for advice; after all there are no better teachers in the field than actual photographers.
With the tips you have just reviewed, you hopefully have a better idea of how photography works as well as some new techniques to make your camera do what you want it to. Start now and use this advice to capture the world in your own unique way.


text:
Discussion on Twitter
Jul 09, 2013| Courtesy by : Associated Press of Pakistan
GUANGZHOU, July 8 (APP): Prime Minister Muhammad Nawaz Sharif Monday left here after completing his successful five days official visit to China. At the airport, the Deputy Provincial Governor, Assistant Foreign Minister, Chinese Ambassador to Pakistan saw off the Prime Minister. From Pakistan's side Advisor to Prime Minister on Foreign Affairs Tariq Fatemi, Foreign Secretary Jalil Abass Jilani, Ambassador Masood Khalid, Consul General Guangzhou Babar Amin and senor diplomats were also present at the airport. During his visit, Prime Minister visited Beijing,Shanghai and Guangzhou. In Beijing, Prime Minister held detailed and constructive meetings with President Xi Jinping and Premier Li Keqiang. The Prime Minister also discussed with the Chinese leadership how to address the country's energy problem and development of infrastructure.
The two countries signed eight Memorandum of Understanding and Agreements following the meeting between Muhammad Nawaz Sharif and Premier Li Keqiang including Pakistan-China Economic Corridor accord.
The Prime Minister also held detailed meetings with heads and chief executives of banks, financial institutes and corporate leaders.
In these meetings, Prime Minister said that Pakistan is faced with energy shortfall as a result our economic development was affecting.
He invited heads and chief executives of Chinese enterprises to come forward and help Pakistan in setting up power plant and development of infrastructures.
The Prime Minister also discussed with Chinese companies for High-Speed railway network from Karachi to Peshawar to ensure comfortable journey to the masses.
Terming the Pakistan-China Economic Corridor as 'Game Changer', Prime Minister informed at these meetings that Special Economic Zone would also be set up along the Corridor that would provide immense business opportunities to population living in surrounding areas.
At the meetings with Chinese leadership, the Prime Minister said China has agreed to waive off the condition of insure cover on Chinese projects.
The Prime Minister also met with Chairman National People's Congress Zhang Deijang. Both leaders exchanged views on bilateral relationship and means to cement it further.The Prime Minister visited Shanghai on Saturday in state of the art High Speed Train. During the journey, Prime Minister held a number of meetings. He also talked with the senior officials of the High Speed management project and got details about the train operation and cost.
The train runs at the maximum speed of 310 Kilometers/h and cover the 1310 kilometer distance between Beijing to Shanghai in less than five hours.
At these meetings arranged in the train, a number of Chinese companies evinced keen interest in construction of various projects including power plants, high speed train, Basha dams, optic fiber and motorways.
In Shanghai, the Prime Minister addressed Pakistan-China Energy Forum in which President and Chief Executive Officers of over 50 prominent companies participated.
The Prime Minister held meeting with the Party Secretary, Shanghai Han Zheng.
Later, he hosted a dinner for the visiting dignitary and members of his entourage.
From Shanghai, the Prime Minister and members of his entourage travelled to Guangzhou in special plane provided as a gesture of goodwill by the Chinese government to the distinguished guest.
China Southern Grid Corporation (CSG) the country's top power manufacturing company held a detailed briefing for the Prime Minister.
The Prime Minister showed keen interest in company's business activities and power generation. It was informed that the company provides electricity to five provinces of China, besides Hong Kong.
The Prime Minister discussed with company President how to reduce the line losses and power theft and sought his assistance in this regard.
The Prime Minister also met with the Governor of Guangdong province, Zhu Xiaodan and discussed on bilateral relations. On the occasion, the Governor Informed the Prime Minister that a large number
of Pakistani traders were doing business from this province. An official informed that 60 per cent bilateral trade between the two countries is being carried out from this province.
The Governor also called on promotion of tourism between the two sides.
Later, Governor Zhu hosted a dinner for the Prime Minister and members of his delegation.
(Courtesy: Associated Press of Pakistan)


text:
Apple Podcasts | Google Podcasts
Session 187
Phil is back for some more MCAT passage. Today, we cover Passage 5 of Blueprint's full-length one which is all about titration. If you haven't yet, go sign up for their full-length one at Blueprint MCAT.
For more of premed resources, go check out premedpodcast.com where we have lots of other podcasts for premed students. The OldPreMeds Podcast is where we help non-traditional students on their journey to medical school. The Premed Years Podcast is where I talk about everything premed and applications. Sometimes, I interview deans of medical schools and admissions committee members, and much more.
If you would like to follow along on YouTube, go to premed.tv.
Listen to this podcast episode with the player above, or keep reading for the highlights and takeaway points.
[03:55] Passage 5 (Questions 23-26)
Potentiometric titration is a useful means of characterizing an acid. Instead, the cell potential is measured across the analyte solution. When cell potential is plotted against titrant volume added, the equivalence point is the cell potential at the inflection point, the midpoint of the steep segment of the titration curve.
It's similar to regular hydration where you add a base, and we have an equivalence point. But we're also adding in this ability to measure the voltage with the electric potential. And so that's why it's a potentiometric or potentio-measuring thing. And so that's telling us when we reach this equivalence point, rather than looking at the actual indicator.
Continuation of Passage…
For polyprotic acids, acidic hydrogen will produce an inflection point only if it is not very weakly acidic and if its ionization constant differs from that of any other acidic hydrogen of the acid by at least a factor of 104.
Captopril (molecular weight: 217.29 g/mol), shown in Figure 1, is a competitive inhibitor of angiotensin-converting enzyme (ACE).
Figure 1 Captopril
Students studying captopril were provided the following in vivo IC50 values (the minimum plasma concentration need to inhibit 50% of target enzyme activity in vivo) for captopril inhibition of ACE under different pH conditions.
IC50 is the minimum concentration of whatever it is that we're talking about needed to inhibit 50%. So it's the inhibitory concentration at 50%.
Table 1 Captopril IC50 values
|pH range
|IC50 (mean 士 standard deviation)
|0.058 士 0.013 pM
|0.012 士 0.004 pM
|0.069 士 0.017 pM
The pKa for the salt hydro group is 9.8. And the pKa of the carboxylic acid is 3.7, which are those middle points in those pH ranges. They have the pH up to 3.7, from there to 9.6, and then above 9.6. So they're telling us that what's happening at these different points is we're dealing with the molecule.
IC50 is the amount of the drug we need to shut down 50% of the ACE enzymes. And so a smaller number is a more powerful drug because I don't need very much of it to shut down 50% of angiotensin-converting enzyme.
While bigger IC50 is actually a less powerful drug. And so that's something that seems counterintuitive, where the smaller the number, you need less of it because it's telling you how much you need to shut down the enzymes.
[09:33] Continuation of Passage 5
Students then performed a potentiometric titration of captopril in order to determine the captopril content contained in a tablet formulation. Two tablets were ground and homogenized, producing 104.4 grams of fine powder. The powder was then dissolved in 100 mL of water and titrated with a solution of 2x 10-2 M NaOH. The potentiometric titration curve obtained, along with a plot of the rate of change of potential during the titration, is shown in Figure 2.
Figure 2 (a) Potentiometric titration curve of captopril in NaOH solution; (b) Rate of change of cell potential
You could see the traditional titration curve appearance with that s-shaped curve. And then we have this sharp peak of the cell potential, right around 7.5 or something like that. It's telling us that that's probably where the equivalence point is happening.
Remember from the first paragraph that they told us that we get this indicator through the potential when we hit the equivalence point rather than using an indicator. And so they use that and Figure 2.
[11:31] Question 23
How many noles of captopril were present in the original analyte solution tested?
(A) 7.5 x 10-5 moles
(B) 1.5 x 10-4 moles
(C) 7.5 x 10-3 moles
(D) 1.5 x 10-2 moles
Thought Process Behind the Correct Answer:
They're trying to figure out just how much captopril is in this container. How many moles of it is in a container and they did this by titrations curves. The titration is to figure out how much is there. The key here is that anytime you hit an equivalence point, the moles of the acid are equal to the moles of the base. And that's the point of the equivalence point which is equivalent acid-base.
7.5 mL is not how many actual moles of the NaOH is in there. It's just how many drops we put in there. But they do give us the concentration of it.
You can just multiply those two because you got mol/L x L, if you convert the mills to liters. So then you're just left with moles, and so it's going to be 2 x 10-2 molarity times 7.5 x 2-3 once you convert that to liters, so 2 x 7.5 is 15.
And then you end up with 1.5 times 10-4 moles per liter when you convert that back to scientific notation, so the answer is B.
Correct Answer: B
[16:21] Question 24
If the students perform an enzyme inhibition assay using captopril, which of the following changes in the kinetic parameters of ACE should be expected?
(A) Vmax decreased; Km unchanged
(B) Vmax decreased; Km increased
(C) Vmax unchanged; Km decreased
(D) Vmax unchanged; Km increased
Thought Process Behind the Correct Answer:
You have to know how these different inhibitors work in terms of competitive, noncompetitive. Then it says a competitive inhibitor right above Figure 1.
So the Vmax is how fast this angiotensin-converting enzyme can work at maximum speed. So generally, you add an inhibitor and it slows down a reaction.
The Vmax is like how fast can this enzyme work? Now, if you had a competitive inhibitor, that's going to compete for the active site with the angiotensin because they're both going to go into the same thing. If I keep adding more and more angiotensin, my inhibitor isn't going to get a chance to get in there.
It's like if you're trying to get in the Apple Store, and there are 10 million people trying to get in. I'm being outcompeted because there are too many people trying to go for that spot. In this scenario of an infinite substrate, it tells that this enzyme is still going to work as fast as it normally does.
Hence, its Vmax is going to be unchanged because the inhibitor is not going to get a chance to go in there and shut it down.
At this point, we know it's going to be either C or D because we know that Vmax can't be altered.
Km is how much substrate needed to add to get to that 1/2 Vmax. If I added an inhibitor, that's going to make it harder for the substrate in there. So I'm going to have to add more substrate than normal to get that to the half of its maximum speed.
And so our Km which is a measurement of how much substrate we need to reach our half maximum velocity, that's gonna go up and so the answer has got to be D.
Correct Answer: D
[20:22] Differentiating Competitive Inhibitors vs Noncompetitive
So the Vmax goes or the velocity will decrease when you add an inhibitor, but if you add enough substrate, then the inhibitor can't do anything.
Imagine that your job is to go in and shut down the Apple Store, you're trying to inhibit the Apple Store because you work for Samsung.
A competitive inhibitor is going to try to get into the same spot that everything else is trying to get into.
A noncompetitive inhibitor is going to go slick in the back door and shut it down. It doesn't matter how many people are trying to get in the front door, but you're going to be able to shut down the enzyme all the time.
But in the case of a competitive inhibitor, if you keep adding substrate eventually, it's like there are 10 million people trying to get to that front door. Then you're trying to get it shut down but you can't. Because there's just you're being outcompeted. It's like it's all that extra.
[21:59] Question 25
Which of the following protonation states of the captopril and carboxyl groups is required to maximize captopril's inhibition of angiotensin-converting enzyme (ACE)?
(A) Deprotonated thiol and protonated carboxyl
(B) Protonated thiol and deprotonated carboxyl
(C) Deprotonated thiol and deprotonated carboxyl
(D) Protonated thiol and protonated carboxyl
Thought Process Behind the Correct Answer:
This protonation stuff is one of the things that causes people some confusion. The nucleus has just a proton and then it's got one electron. So if you pull that electron, it's just a proton. And so when we talk about protonation states, it's just adding or removing hydrogen.
We're going to have to use Figure 1 in determining the answer here. The pH range where this is most powerful was between 3.8-9.5, which is between the things they give us in Figure 1. So that's going to be higher than one of these. The pH is going to be higher. Then the pKa for carboxylic acid is going to be lower than the pKa for the salt hydro group, the SH group. So just off of that, it's probably going to be ones protonated and ones deprotonated.
If it was below both of them, they're both going to be the same. If the pH was above both of them, they would both be the same. And so just from that, the answer is probably A or B at that point.
Now, a lot of times students struggle a little bit with this, but I think the easiest way to think about this is to figure out whether it's going to have hydrogens on it or not at these different pH's. Think about what's going to happen at the lowest pH if there's an infinite number of hydrogens. Everything's going to have hydrogen on it. At a really low pH, the waters just full of hydrogens.
And so at a pH of one, all of these things are going to have hydrogens on them. And then as we remove hydrogens from there, aka, we raise the pH by removing the hydrogens. Hydrogens are going to start to fall off this molecule. After we pass a pH of 3.7, the hydrogens are going to start to fall off the carboxylic acid. So that'll be deprotonated. But the salt, hydro will still be protonated. And then as you go above 9.8, then the hydrogens will fall off of that also. And so then everything will be deprotonated. So the answer is C.
Think of a low ph as being bathed in hydrogens. And as you increase the pH, those hydrogens are falling off and then use the pKa to determine where they're falling off sooner rather than later. Those are the turning points.
Correct Answer: C
[26:54] Question 26
According to the data in Table 1, what mass of captopril must be dissolved in 3 L of plasma at pH of 7.4 to inhibit 50% of ACE enzyme activity in vivo? Assume an equal volume of distribution.
(A) 7.9 pg
(B) 7.9 ng
(C) 7.9 μg
(D) 7.9 g
Thought Process Behind the Correct Answer:
Looking in terms of the units, we have 3 L and we're going to need the 0.012 micromolar, which is mol/L. But the answer is here is in grams, and we're given captopril's weight of 217.29 grams per mole.
If we multiply 3 L whatever mol/L, the L cancels out and we're left with moles. So if we take that x grams per mole, the mole will cancel out more of the grams. And so the answer to this one is to just multiply all three of those numbers together.
3 L x 0.012 micromolar x 217 grams per mole which is going to round to 220. But we're not even really that worried about that anyway, because the answer is going to come out to be 7.9.
0.012 x 10-6 mol/L when you convert it to micromolar then x 3 L and x 220 grams, so you get 7.9 x 10-6. So the answer is micrograms.
Correct Answer: C
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Harvard Law School Makes Online Zero-L Course Free for All U.S. Law Schools Due to Coronavirus
For Kennedy School Fellows, Epstein-Linked Donors Present a Moral Dilemma
Tenants Grapple with High Rents and Local Turnover at Asana-Owned Properties
In April, Theft Surged as Cambridge Residents Stayed at Home
The History of Harvard's Commencement, Explained
Eight meets are scheduled for the University cross-country team this fall according to the schedule of Manager J. C. Collins '25, which is announced for the first time, subject to the approval of the Athletic Committee. A triple meet with Yale and Princeton in Nassau and the Intercollegiate meet at Van Cortlandt park are the features of the schedule, which follows:
October 10.--Middlebury.
October 17.--Holy Cross.
October 24.--Dartmouth.
October 31.--Tech.
November 7.--Springfield.
November 15.--Yale and Princeton at Princeton.
November 24.--I. C. A. A. A. A. meet at New York.
Practice so far is general warming up runs. Speed trials were also given on the track yesterday afternoon.
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|Mike Adams named second most influential person in alternative media
|Scientists shocked to discover that Earth's mantle is moving at TEN TIMES the rate we all thought... Massive changes in tectonic plates can happen 'chaotically'


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by Frederic Block ‧ RELEASE DATE: Oct. 10, 2017
A historical novel dramatizes a defense attorney's perilous stand against judicial corruption in Brooklyn.
Troy Jackson is an unusual candidate for a murder suspect—a clean-cut black guidance counselor with a relatively clean criminal record, he owns a home in Brooklyn with his pregnant wife. Nevertheless, he's arrested for the killing of Menachem Mendel Bernstein, a crime committed seven years ago, on the strength of highly questionable eyewitness testimony. Troy's wife contacts Ken Williams, a black defense attorney with a reputation for championing the fair judicial treatment of African-Americans in New York City. Meanwhile, Williams has already taken on the case of Jojo Jones, a black inmate who was convicted of the murder of Bernstein's father, a rabbi, 16 years earlier. Jones was found guilty—without any physical evidence—on the basis of testimony that is revealed to be the fruit of brazen coercion. The deeper Williams digs into the case, the more clearly he discerns a disturbing pattern of widespread corruption on the parts of District Attorney James Neary and Anthony Racanelli, his top prosecutor. And once Williams is able to successfully win Jones' freedom, mortifying Neary and Racanelli, they respond by arresting him for the assault of a police officer and getting his law license temporarily suspended. Pushed to the brink and filled with rage, Williams decides to challenge Neary for his position and runs for district attorney, a decision quickly followed by death threats and the bombing of his office, which kills Jones. Block (Disrobed: An Inside Look at the Life and Work of a Federal Trial Judge, 2012)—a U.S. district judge who has spent nearly a quarter century on the bench—vividly depicts a city roiled by racial tensions and a district attorney's office cravenly eager to kowtow to its Jewish campaign donors. The novel does double duty as history, skillfully recounting New York's race riots and their lasting effects as well as some of the city's most incendiary scandals. The writing is crisp if less than literary, but the story—closely based on the life of lawyer Ken Thompson, the first black district attorney of Brooklyn—is as gripping as any fictional crime tale.A relentlessly paced legal drama that ably chronicles a city's past racial tensions.
Pub Date: Oct. 10, 2017
Page Count: 368
Publisher: SelectBooks
Review Posted Online: Nov. 28, 2017
Kirkus Reviews Issue: Jan. 15, 2018
Review Program: Kirkus Indie
Categories: GENERAL THRILLER & SUSPENSE | THRILLER | CRIME & LEGAL THRILLER
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by Lisa Jewell ‧ RELEASE DATE: April 24, 2018
Ten years after her teenage daughter went missing, a mother begins a new relationship only to discover she can't truly move on until she answers lingering questions about the past.
Laurel Mack's life stopped in many ways the day her 15-year-old daughter, Ellie, left the house to study at the library and never returned. She drifted away from her other two children, Hanna and Jake, and eventually she and her husband, Paul, divorced. Ten years later, Ellie's remains and her backpack are found, though the police are unable to determine the reasons for her disappearance and death. After Ellie's funeral, Laurel begins a relationship with Floyd, a man she meets in a cafe. She's disarmed by Floyd's charm, but when she meets his young daughter, Poppy, Laurel is startled by her resemblance to Ellie. As the novel progresses, Laurel becomes increasingly determined to learn what happened to Ellie, especially after discovering an odd connection between Poppy's mother and her daughter even as her relationship with Floyd is becoming more serious. Jewell's (I Found You, 2017, etc.) latest thriller moves at a brisk pace even as she plays with narrative structure: The book is split into three sections, including a first one which alternates chapters between the time of Ellie's disappearance and the present and a second section that begins as Laurel and Floyd meet. Both of these sections primarily focus on Laurel. In the third section, Jewell alternates narrators and moments in time: The narrator switches to alternating first-person points of view (told by Poppy's mother and Floyd) interspersed with third-person narration of Ellie's experiences and Laurel's discoveries in the present. All of these devices serve to build palpable tension, but the structure also contributes to how deeply disturbing the story becomes. At times, the characters and the emotional core of the events are almost obscured by such quick maneuvering through the weighty plot.Dark and unsettling, this novel's end arrives abruptly even as readers are still moving at a breakneck speed.
Pub Date: April 24, 2018
Page Count: 368
Publisher: Atria
Review Posted Online: Feb. 6, 2018
Kirkus Reviews Issue: Feb. 15, 2018
Categories: GENERAL THRILLER & SUSPENSE | SUSPENSE | FAMILY LIFE & FRIENDSHIP | SUSPENSE
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by Lisa Jewell
by Lisa Jewell
by Lisa Jewell
by Alex Michaelides ‧ RELEASE DATE: Feb. 5, 2019
A woman accused of shooting her husband six times in the face refuses to speak.
"Alicia Berenson was thirty-three years old when she killed her husband. They had been married for seven years. They were both artists—Alicia was a painter, and Gabriel was a well-known fashion photographer." Michaelides' debut is narrated in the voice of psychotherapist Theo Faber, who applies for a job at the institution where Alicia is incarcerated because he's fascinated with her case and believes he will be able to get her to talk. The narration of the increasingly unrealistic events that follow is interwoven with excerpts from Alicia's diary. Ah, yes, the old interwoven diary trick. When you read Alicia's diary you'll conclude the woman could well have been a novelist instead of a painter because it contains page after page of detailed dialogue, scenes, and conversations quite unlike those in any journal you've ever seen. " 'What's the matter?' 'I can't talk about it on the phone, I need to see you.' 'It's just—I'm not sure I can make it up to Cambridge at the minute.' 'I'll come to you. This afternoon. Okay?' Something in Paul's voice made me agree without thinking about it. He sounded desperate. 'Okay. Are you sure you can't tell me about it now?' 'I'll see you later.' Paul hung up." Wouldn't all this appear in a diary as "Paul wouldn't tell me what was wrong"? An even more improbable entry is the one that pins the tail on the killer. While much of the book is clumsy, contrived, and silly, it is while reading passages of the diary that one may actually find oneself laughing out loud.Amateurish, with a twist savvy readers will see coming from a mile away.
Pub Date: Feb. 5, 2019
Page Count: 304
Publisher: Celadon Books
Review Posted Online: Nov. 4, 2018
Kirkus Reviews Issue: Nov. 15, 2018
Categories: GENERAL THRILLER & SUSPENSE | SUSPENSE | THRILLER | SUSPENSE | PSYCHOLOGICAL THRILLER
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