text: NASDAQ:RUBYRubius Therapeutics Stock Price, Forecast & News Adding Choose a watchlist: Adding You have already added five stocks to your watchlist. Upgrade to MarketBeat Daily Premium to add more stocks to your watchlist. Adding Rubius Therapeutics Inc Please log in to your account or sign up in order to add this asset to your watchlist. Log In and Add $5.01 +0.10 (+2.04 %) (As of 08/3/2020 04:00 PM ET) Add Compare Share Today's Range$4.84Now: $5.01▼$5.0850-Day Range$4.91MA: $5.97▼$6.6352-Week Range$3.35Now: $5.01▼$14.44Volume128,287 shsAverage Volume354,390 shsMarket Capitalization$403.18 millionP/E RatioN/ADividend YieldN/ABeta2.18 ProfileAnalyst RatingsAdvanced ChartCompetitorsEarningsInsider TradesInstitutional OwnershipHeadlinesSocial Media Rubius Therapeutics, Inc. focuses on the development of red cell therapeutics (RCTs) for the treatment of patients with severe diseases. The company is developing various RCTs, such as RTX-134 for treatment of phenylketonuria; RTX-Uricase for treatment of chronic refractory gout; RTX-CBS for treatment of homocystinuria; and RTX-OxOx for the treatment of second-line hyperoxaluria. It is also developing RTX-240 and RTX-224 for the treatment of cancer; and RTX-aAPC to treat solid and hematological cancers. In addition, the company is developing RTX-T1D for treating type 1 diabetes; and RTX-PV for treating pemphigus vulgaris. The company was founded in 2013 and is headquartered in Cambridge, Massachusetts.Read More Beat the Market (BTM) Rank™ 3.1 Analyst's Opinion Consensus RatingRubius Therapeutics has received a consensus rating of Hold. The company's average rating score is 2.17, and is based on 2 buy ratings, 3 hold ratings, and 1 sell rating.Price Target Upside/DownsideAccording to analysts' consensus price target of $10.00, Rubius Therapeutics has a potential upside of 99.6% from its current price of $5.01.Amount of Analyst CoverageRubius Therapeutics has received no research coverage in the past 90 days. Previous Next 2.3 Community Rank Outperform VotesRubius Therapeutics has received 160 "outperform" votes. (Add your "outperform" vote.)Underperform VotesRubius Therapeutics has received 188 "underperform" votes. (Add your "underperform" vote.)Community SentimentRubius Therapeutics has received 54.02% "underperform" votes from our community.MarketBeat's community ratings are surveys of what our community members think about Rubius Therapeutics and other stocks. Vote "Outperform" if you believe RUBY will outperform the S&P 500 over the long term. Vote "Underperform" if you believe RUBY will underperform the S&P 500 over the long term. You may vote once every thirty days. Previous Next 0.0 Dividend Strength Dividend YieldRubius Therapeutics does not currently pay a dividend.Dividend GrowthRubius Therapeutics does not have a long track record of dividend growth. Previous Next 2.0 Company Ownership Insider Buying vs. Insider SellingIn the past three months, Rubius Therapeutics insiders have not sold or bought any company stock.Percentage Held by Insiders58.40% of the stock of Rubius Therapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.Percentage Held by Institutions92.99% of the stock of Rubius Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company. Previous Next 0.6 Earnings and Valuation Earnings GrowthEarnings for Rubius Therapeutics are expected to grow in the coming year, from ($2.06) to ($1.91) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Rubius Therapeutics is -2.23, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Rubius Therapeutics is -2.23, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioRubius Therapeutics has a P/B Ratio of 1.46. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities. Previous Next Analyst Opinion: 3.1Community Rank: 2.3Dividend Strength: 0.0Insider Behavior: 2.0Valuation: 0.6 5 -4 -3 -2 -1 -Overall Beat the Market Rank™1.60 out of 5 stars Industry, Sector and Symbol Stock Exchange NASDAQ Industry Biological products, except diagnostic Sub-IndustryN/A SectorMedical Current SymbolNASDAQ:RUBY Previous Symbol CUSIPN/A CIKN/A Webwww.rubiustx.com Phone617-679-9600Debt Debt-to-Equity Ratio0.36 Current Ratio8.99 Quick Ratio8.99Price-To-Earnings Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/A Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book Value$3.44 per share Price / Book1.46Profitability EPS (Most Recent Fiscal Year)($2.08) Net Income$-163,460,000.00 Net MarginsN/A Return on Equity-61.83% Return on Assets-44.47%Miscellaneous Employees142 Outstanding Shares80,476,000Market Cap$403.18 million Next Earnings Date8/11/2020 (Estimated) OptionableNot Optionable $5.01 +0.10 (+2.04 %) (As of 08/3/2020 04:00 PM ET) 30 days | 90 days | 365 days | Advanced Chart Receive RUBY News and Ratings via Email Sign-up to receive the latest news and ratings for RUBY and its competitors with MarketBeat's FREE daily newsletter. Rubius Therapeutics (NASDAQ:RUBY) Frequently Asked Questions How has Rubius Therapeutics' stock been impacted by COVID-19 (Coronavirus)? Rubius Therapeutics' stock was trading at $6.55 on March 11th, 2020 when Coronavirus (COVID-19) reached pandemic status according to the World Health Organization (WHO). Since then, RUBY shares have decreased by 23.5% and is now trading at $5.01. View which stocks have been most impacted by Coronavirus. Do Wall Street analysts recommend investors buy shares of Rubius Therapeutics? 6 Wall Street analysts have issued "buy," "hold," and "sell" ratings for Rubius Therapeutics in the last year. There are currently 1 sell rating, 3 hold ratings and 2 buy ratings for the stock, resulting in a consensus recommendation of "Hold." View analyst ratings for Rubius Therapeutics. When is Rubius Therapeutics' next earnings date? Rubius Therapeutics is scheduled to release its next quarterly earnings announcement on Tuesday, August 11th 2020. View our earnings forecast for Rubius Therapeutics. How were Rubius Therapeutics' earnings last quarter? Rubius Therapeutics Inc (NASDAQ:RUBY) posted its quarterly earnings data on Monday, May, 11th. The company reported ($0.60) earnings per share for the quarter, missing analysts' consensus estimates of ($0.56) by $0.04. View Rubius Therapeutics' earnings history. What price target have analysts set for RUBY? 6 equities research analysts have issued twelve-month price targets for Rubius Therapeutics' shares. Their forecasts range from $4.00 to $28.00. On average, they expect Rubius Therapeutics' stock price to reach $10.00 in the next twelve months. This suggests a possible upside of 99.6% from the stock's current price. View analysts' price targets for Rubius Therapeutics. Has Rubius Therapeutics been receiving favorable news coverage? Headlines about RUBY stock have trended somewhat positive on Tuesday, InfoTrie reports. The research group identifies negative and positive news coverage by reviewing more than six thousand blog and news sources. The firm ranks coverage of publicly-traded companies on a scale of negative five to five, with scores closest to five being the most favorable. Rubius Therapeutics earned a media sentiment score of 1.8 on InfoTrie's scale. They also assigned news coverage about the company a news buzz of 0.0 out of 10, indicating that recent news coverage is extremely unlikely to have an effect on the company's share price in the next several days. View the latest news about Rubius Therapeutics. Who are some of Rubius Therapeutics' key competitors? Some companies that are related to Rubius Therapeutics include Mesoblast (MESO), Bill.com (RVMD), Adverum Biotechnologies (ADVM), NanoString Technologies (NSTG), Forma Therapeutics (FMTX), Coherus Biosciences (CHRS), Alector (ALEC), Regenxbio (RGNX), Cortexyme (CRTX), Nantkwest (NK), Adaptimmune Therapeutics (ADAP), Compugen (CGEN), I-Mab (BDTX), Vaxart (VXRT) and Translate Bio (TBIO). View all competitors. What other stocks do shareholders of Rubius Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some companies that other Rubius Therapeutics investors own include Opko Health (OPK), Sorrento Therapeutics (SRNE), TG Therapeutics (TGTX), Crispr Therapeutics (CRSP), Viking Therapeutics (VKTX), Canopy Growth (CGC), Corbus Pharmaceuticals (CRBP), Dicerna Pharmaceuticals (DRNA), Editas Medicine (EDIT) and Amicus Therapeutics (FOLD). Who are Rubius Therapeutics' key executives? Rubius Therapeutics' management team includes the following people: Mr. David R. Epstein, Exec. Chairman (Age 57)Dr. Christopher L. Carpenter M.D., Ph.D., Chief Medical Officer (Age 63)Dr. Pablo J. Cagnoni, CEO, Pres & Director (Age 56)Mr. Andrew M. Oh, Chief Financial Officer (Age 47)Ms. Joanne M. Protano, Sr. VP of Fin. & Operations (Age 50) When did Rubius Therapeutics IPO? (RUBY) raised $200 million in an initial public offering on Wednesday, July 18th 2018. The company issued 9,500,000 shares at a price of $20.00-$22.00 per share. J.P. Morgan, Morgan Stanley, Jefferies and Leerink Partners served as the underwriters for the IPO. What is Rubius Therapeutics' stock symbol? Rubius Therapeutics trades on the NASDAQ under the ticker symbol "RUBY." Who are Rubius Therapeutics' major shareholders? Rubius Therapeutics' stock is owned by a number of retail and institutional investors. Top institutional shareholders include SG Americas Securities LLC (0.05%) and ProShare Advisors LLC (0.02%). Company insiders that own Rubius Therapeutics stock include Christina M Coughlin, Christopher L Carpenter, David R Epstein, Pablo J Cagnoni, Robert Langer and Torben Straight Nissen. View institutional ownership trends for Rubius Therapeutics. Which institutional investors are buying Rubius Therapeutics stock? RUBY stock was acquired by a variety of institutional investors in the last quarter, including SG Americas Securities LLC, and ProShare Advisors LLC. Company insiders that have bought Rubius Therapeutics stock in the last two years include Christina M Coughlin, David R Epstein, and Pablo J Cagnoni. View insider buying and selling activity for Rubius Therapeutics. How do I buy shares of Rubius Therapeutics? Shares of RUBY can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Vanguard Brokerage Services, TD Ameritrade, E*TRADE, Robinhood, Fidelity, and Charles Schwab. What is Rubius Therapeutics' stock price today? One share of RUBY stock can currently be purchased for approximately $5.01. How big of a company is Rubius Therapeutics? Rubius Therapeutics has a market capitalization of $403.18 million. The company earns $-163,460,000.00 in net income (profit) each year or ($2.08) on an earnings per share basis. Rubius Therapeutics employs 142 workers across the globe. What is Rubius Therapeutics' official website? The official website for Rubius Therapeutics is www.rubiustx.com. How can I contact Rubius Therapeutics? Rubius Therapeutics' mailing address is 399 BINNEY STREET SUITE 300, CAMBRIDGE MA, 02139. The company can be reached via phone at 617-679-9600 or via email at [email protected] This page was last updated on 8/4/2020 by MarketBeat.com Staff 30 Days of MarketBeat All Access for $1.00 Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools: Best-in-Class Portfolio Monitoring View the latest news, buy/sell ratings, SEC filings and insider transactions for your stocks. Compare your portfolio performance to leading indices and get personalized stock ideas based on your portfolio. Stock Ideas and Recommendations Get daily stock ideas top-performing Wall Street analysts. Get short term trading ideas from the MarketBeat Idea Engine. View which stocks are hot on social media with MarketBeat's trending stocks report. Advanced Stock Screeners and Research Tools Identify stocks that meet your criteria using seven unique stock screeners. See what's happening in the market right now with MarketBeat's real-time news feed. 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84 Lumber Company is looking for individuals to assist in the production of interior doors, exterior doors and other millwork items. Description/Job Summary: The Door Shop Manufacturer is responsible for, but not limited to: Working on a Door Pre-hanging assembly line and keeping up on routine maintenance of equipment Using Power Saws, Air Nail Guns, Staplers and oth...
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84 Lumber is searching for a Contractor Sales Representative. This is an excellent opportunity for you to develop a great career in sales with an industry leader! As a Contractor Sales Representative you are responsible for identifying potential customers, building positive relationships, and creating customer loyalty. Responsibilities include: Selling lumber and b...
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84 Lumber - Lexington, SC
Associate is responsible for building loads for deliveries. In addition, must maintain a safe, clean and well organized lumber yard / warehouse, load and unload lumber and/or building supplies, and operate a forklift. Other duties as assigned. Essential Functions: Build loads for delivery Load and unload lumber and building supplies Operates ...
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As one of the industry's leading suppliers of building materials, we are always looking for our future leaders. Our Manager Trainee program is one of the finest in the industry and provides a solid foundation for you to build your future on. This position is our entry-level position into the management career path, and from this point you can build your own future with the tools and sk...
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Responsibilities for the Area Install Manager include: Management of the sales agenda for the Installed Program to ensure budget plus performance Providing sales support by attending customer meetings with sales staff Recruitment of subcontractors Recruitment of qualified candidates for Installed Management positions. Responsibility for new IM train...
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**We are looking for people in Florence, SC and Sumter, SC*** Construction Services Superintendent / FISMGR (Framing Installed Sales Manager): The FISMGR is responsible for the supervision of, and coordination with, Independent Subcontract framing crews working on 84 Lumber projects. The general scope of management for an 84 Lumber FISMGR can include:

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- Yale-New Haven Hospital Saint Raphael Campus
- Yale New Haven Hospital
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Dr. Lawrence J Hirsch has 3 locations
Dr. Lawrence J Hirsch has the following 2 SPECIALTIES
Specialty Expertise
Dr. Lawrence J Hirsch has the following 9 expertise
- Stroke
- Epilepsy
- Nerve Conduction Studies
- Multiple Sclerosis (MS)
- Migraine Disorder
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1 Award
Castle Connolly Regional Top Doctors (1)
Castle Connolly is America's trusted source for the identification of Top Doctors. Their physician-led research team reviews and screens the credentials of tens of thousands of physicians who are nominated by their peers annually, via a nationwide online process, before selecting those physicians who are regionally or nationally among the very best in their medical specialties. Castle Connolly believes strongly that Top Doctors Make a Difference.
Dr. Lawrence J Hirsch Accepts the Following Insurance
- 800 Howard Ave New Haven , CT (203) 737-1057
- 260 Long Ridge Rd Stamford , CT (203) 785-3865
- 15 York St New Haven , CT 06510
More about Dr. Lawrence J Hirsch
Dr. Hirsch works in New Haven, CT and 3 other locations and specializes in Epileptology and Neurology. Dr. Hirsch is affiliated with Yale-New Haven Hospital Saint Raphael Campus and Yale New Haven Hospital.


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2 Bedroom House For Sale
A well-presented two bedroom cottage situated in an exclusive development with stunning period features throughout and enjoying easy access to popular landmarks and the mainline to London (Kings Cross 1 hr 14 mins approx).
A stunning Grade II listed cottage adjoining the rather impressive Kelham Hall, situated in an exclusive and high-end development within easy reach of Newark and Southwell. Accommodation briefly includes a full height lounge with vaulted ceilings, exposed beams and stone mullion windows, bespoke kitchen with additional mullion windows looking out over the courtyard garden, two double bedrooms and a contemporary bathroom.
Kelham is a small village 2 miles north-west of Newark, on the main road between Newark and Southwell. The area boasts excellent travel connections, being close to the A46 and A1 trunk road, and with London Kings Cross accessible directly by high speed rail network from Newark (approx 1hr 14mins).
A charming market town steeped in history, Newark-on-Trent is dotted with attractive Georgian architecture, independent stores and relaxed bistros, all centralised around a cobbled market square. Newark enjoys popular heritage sites including Newark Castle where visitors can take tours, view exhibitions or enjoy a stroll through the Victorian gardens. Other local attractions include a state-of-the-art cinema, a popular museum, art gallery and the town's notable Palace Theatre. There is a handful of interesting independent stores and antique shops in the town centre and a number of large supermarkets also close by. Newark Markets are also popular among locals and visitors alike, offering fresh organic produce, locally-caught fish and artisan gifts. Your local Waitrose is conveniently located in this increasingly popular market town.
Additional shopping facilities can be found in nearby Southwell with an outstanding choice of shops. Family butchers, grocers, ironmongers, a delicatessen and fashion boutiques are interspersed with convenience stores, confectioners, pharmacies, a post office, traditional pubs and restaurants, and food takeaways. The independent shops are complemented by a large Co-op supermarket, a Saturday market selling local produce, and fresh fish stalls on Wednesdays and Fridays. In addition to the celebrated attractions of the town, from the stately Minster and Prebendal Houses to the historic Workhouse and half-timbered Saracen's Head hotel, there is a choice of sporting and leisure activities. Southwell has a racecourse and a golf club, and there is a second golf centre at Norwood Park that is entered, like the prestigious Norwood Park events venue, via a driveway opposite Imperial Gardens. The town has rugby, cricket and football clubs and a leisure centre with swimming pools and a fitness suite.
The surrounding area offers excellent opportunities for walking and cycling around the local countryside, exploring Heritage Trails, and visiting attractions like the Museum of Timekeeping, White Post Farm for family days out. Eden Hall Spa is nearby for personal pampering, as well as the popular Southwell Racecourse next door to the village.
Newark offers several Primary, Secondary and 6th Form establishments. The property is close to various primary schools with establishments rated Good by Ofsted including Holy Trinity Catholic Academy, Christ Church Church of England Infant & Nursery School and Mount Church of England Primary & Nursery School in close proximity. The town also has two secondary education academies.
The "outstanding" Ofsted rated Minster School is a short drive to Southwell.
15'8" x 15'5
Kitchen Diner
20'11" x 13'5
Bedroom One
14'2" x 9'3
8'0" x 7'6
Bedroom Two
11'3" x 11'1
The property is approached from the front garden which is mainly laid to lawn with hedges and flower beds.
To the rear of the property there is a courtyard garden with a large paved area, ideal for outdoor eating and entertaining, as well as borders to either side and inset silver birch trees. A rear gate leads to a private parking area and a single garage.
The property is centrally heated throughout with mains water, drainage, gas and electricity all connected.
EPC Exempt
Band: B
The property is offered for sale by Private Treaty.
Freehold with vacant possession upon completion.
Drafted and photographs taken following clients' instructions of July 2020.
Strictly by prior arrangement with the Agents (01476 515329).
For further details please contact Mount & Minster:
e: email@example.com
No EPC available for this property
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Heechul's Message on His Fancafe – 5jib is the Last Album?1 August 2011 at 8:52 AM | Posted in Super Junior | Leave a comment
Tags: 5jib, Fancafe, Heechul, Super Junior
110801 Kim Heechul left a message on his fan-cafe at 1:39am
Title: It's been a long time ^-^
Actually, I was not playing cafe, so I've forgotten my user ID & password. keke Finally I've found it. ^-^
Has been using twitter only. Haha Seems like is the first message after a long time ^-^ SUJU will be making a Come Back this week. Because it's the last album, I gave my everything. My empty period.. ^-^
People who are young r having your holidays? People who are older are doing well in your career? As I'm sending away my end of 20 years (old), I have many thoughts in mind. I will also work hard as an grown-up adult ^-^ Though I hv to make my character "die" (change his character) first ㅠㅠ And also I hv thoughts that I should take good care of my periphery ^-^ I should stop here today ^-^
Source: Psycho蝉儿 shared by: @HeechulSJFacts]
cr: @SJFever
Reposted by: cicillia @ SEI (shawolelfindo.wordpress.com)
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Latest in Mena Massoud
Animated Film 'Lamya's Poem', With 'Aladdin' Star Mena Massoud, Launches Sales With WestEnd & ICM – Cannes
WestEnd Films has boarded international sales on Lamya's Poem, the animated feature whose voice cast includes Mena Massoud (Aladdin), Millie Davis (Wonder) and Faran Tahir (Iron Man). The film charts the story of a 12-year-old Syrian refugee who is given a book of poetry of classic 13th-century Persian poet, Rumi. As…
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Canton firefighters had to close a section of Sixth Street SW and evacuate some houses Friday night because of a gas leak at one of the houses. No injuries were reported.
Firefighters evacuated several houses and closed a section of Sixth Street SW Friday night after natural gas began leaking from one of the houses.
The incident in the 3100 block of Sixth Street SW kept fire crews tied up for more than 90 minutes.
No injuries were reported and most of the families returned to their homes once the leak was stopped.
According to radio traffic, a foundation wall at a house in the 3100 block collapsed and the gas meter was damaged. The leak occurred when the meter pulled away from the gas line.
Firefighters has to wait nearly an hour for a utility crew to shut off electrical service to the house with the gas leak. Once power was off, crews were able to assess the damage.


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Santa Monica Pier
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Right next to Venice Beach. Lots of action and amusement park stuff on the pier.
Okay, so it's kinda far... but you can get there on the Metro and if you've got the time you should go check out Santa Monica (the beach and the pier).
Must stop for first time visitors, eat a funnel cake and ride the Ferris Wheel
Want to explore the child within you? Try the Ferris wheel (it won't disappoint) and head to the pier end to see if the resident seal is there. Enjoy some cotton candy or corndogs then head to the beach to play on the gymnastics themed Beach Park (just south of the pier) Some of our favorite Santa…
Take a walk on the beach, ride the Ferris wheel, or try your hand at carnival style games.
This pier has amusement rides, restaurants, arcade, and many street performers. A must see!
While this is a pretty basic boardwalk pier, the beach is lovely around it. Also find the historic and renovated Carousel. A short few hours of family fun featuring a mild roller coaster, scrambler, ferris wheel with beautiful views, dragon swing, boardwalk games and junk food. Tip #1- get the…
Wooden wharf with eateries, shops, high-tech arcade, roller coaster, giant Ferris wheel, other rides & famous 1922 indoor merry-go-round. Fantastic view of the bay and the mountains.
On the beach. Lots of live music in the evenings and different shows. Great views!
The second best reason to come to Los Angeles. You will find everything only 6 miles away.
Santa Monica is one of the greatest cities in the Los Angeles area and home to world's longest stretch of beach. With a beautiful night life and local attractions this place can easily captivate you for days.
Great place for eating, sight seeing, souvenir shopping and go on carnival rides.
World-famous icon famed in endless films TV and ads. A fun pier with full seaside attractions including antique carousel and Mexican restaurant
It's a wonderful place to see, ride rides and eat! you can even access via metro if you don't drive.
Take a day trip to Santa Monica (10-15 miles away) to enjoy the beach, restaurants, and pier. The pier has games, performers, rides, and beautiful views.
The beach and famous Santa Monica Pier are a must-see. The nightlife is great as well, with drink and food specials going on all the time.
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Pedestrian Plaza
"Shop till you drop with all the mini stores on the Boardwalk! You'll never be bored walking the Boardwalk!"
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General Entertainment
"Free! Just pay for parking. Majestic hilltop buildings, the art is Ok, the traveling collections can be great, but the real attraction is the space and gardens themselves. Must not miss!"
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Shopping Plaza
"Outdoor shopping scene. It has everything. A nice walk, crowded on the weekends."
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Παραλιακό μπαρ
"You'll see everything here, from muscle fitness freaks to original 60's hippies and surfers. The epitome of the beach set. Shopping, eateries and great beaches."
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Art Museum
"An always-evolving collection of permanent and featured exhibits in a constantly changing compound of art and activity. Enjoy spectacular dining also on the premises."
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200 Santa Monica Pier
Santa Monica, CA 90401
Τηλέφωνο+1 310-458-8900


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Addressing lifestyle issues is not meant to be a quick fix, and typically does not lead to instant success. However, with unexplained infertility every little bit counts, so don't fret or give up. Do not assume just because the cause of infertility is unexplained, it is untreatable or there is no pathway to parenthood. When a specific cause is not determined for women, and male infertility has also been ruled out, our fertility specialist may begin a course of treatment to improve the chances of conception and pregnancy. The speed with which interventions are offered depends on each individual's own needs and desires as determined by age and other factors.
Clomiphene citrate (Clomid, Serophene) is a medication commonly used for the treatment of women with ovulation disorders as reflected by infrequent or irregular menstrual cycles. Clomid is a pill taken orally for 5 to 7 days, typically on day 3 of a woman's menstrual cycle to induce ovulation. Clomid works at the level of the brain and pituitary gland and facilitates the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). FSH and LH, in turn, stimulate the ovaries to produce eggs and the ovarian hormones estradiol (E2) and progesterone (P4). The initial prescribed dosage of clomid is 50 to 100 mg (one or two tablets) daily at bedtime, or as prescribed by your physician.
The main durations of embryo culture are until cleavage stage (day two to four after co-incubation) or the blastocyst stage (day five or six after co-incubation).[71] Embryo culture until the blastocyst stage confers a significant increase in live birth rate per embryo transfer, but also confers a decreased number of embryos available for transfer and embryo cryopreservation, so the cumulative clinical pregnancy rates are increased with cleavage stage transfer.[30] Transfer day two instead of day three after fertilisation has no differences in live birth rate.[30] There are significantly higher odds of preterm birth (odds ratio 1.3) and congenital anomalies (odds ratio 1.3) among births having from embryos cultured until the blastocyst stage compared with cleavage stage.[71]
Other health related problems could also cause poor egg health, low ovarian reserve, or abnormal immunological responses, which can affect conception. Stress could also play a role. We all know that menstrual cycles can be altered during times of extreme duress- and this can be emotional, physical, or environmental stressors. In these instances, the first steps should be to avoid life stressors, maintain a healthy weight, routinely exercise, avoid smoking, and reduce alcohol intake, all of which may be contributing to unexplained infertility issues.
Our team here at the Center for Human Reproduction has recently developed an infographic explaining one of the most common causes of female infertility: unexplained infertility. This diagnosis is given to 30% of infertility cases and yet, we believe it really is a non-diagnosis. In our clinical experience, with proper testing, up to 90% of unexplained infertility diagnoses can be attributed to treatable causes.
The Latin term in vitro, meaning "in glass", is used because early biological experiments involving cultivation of tissues outside the living organism were carried out in glass containers, such as beakers, test tubes, or Petri dishes. Today, the scientific term "in vitro" is used to refer to any biological procedure that is performed outside the organism in which it would normally have occurred, to distinguish it from an in vivo procedure (such as in vivo fertilisation), where the tissue remains inside the living organism in which it is normally found.
New Brunswick provides partial funding through their Infertility Special Assistance Fund – a one time grant of up to $5,000. Patients may only claim up to 50% of treatment costs or $5,000 (whichever is less) occurred after April 2014. Eligible patients must be a full-time New Brunswick resident with a valid Medicare card and have an official medical infertility diagnosis by a physician.[150]
The treatment options for unexplained infertility are several and the treatment results are promising. Expectant management can be recommended if the woman is under 28-30 years of age and the infertility duration is less than 2-3 years. In vitro fertilization (IVF) has revolutionized the treatment of infertile couples, as well as profoundly increasing the basic understanding of human reproduction. IVF can be used as both a diagnostic and a therapeutic tool in couples with unexplained infertility. The pregnancy rates with IVF are good, at 40% per treatment cycle. In addition, the outcome of pregnancies among women with unexplained infertility is generally comparable to that of spontaneous and other pregnancies using assisted reproductive technologies.
For five to six days following fertilization, the developing embryos are cultured in the laboratory until the blastocyst stage of development has been reached. This represents growth of about 200 cells. We at RMA culture embryos exclusively to the blastocyst stage, because published data demonstrates that extended embryo culture results in improved implantation rates and pregnancy outcomes. This means we will never do an embryo biopsy – or an embryo transfer – at three days, or anything less than the blastocyst stage.
Bloating: Fertility medications can heavily impact how your body retains water, leading to the dreaded side effect of bloating. This is especially common in your midsection, where fluid can build up near the ovaries (creating abdominal tenderness, too). You can combat bloating by increasing your fluid intake and participating in light exercise such as walking.
In December 2015, the Ontario provincial government enacted the Ontario Fertility Program for patients with medical and non-medical infertility, regardless of sexual orientation, gender or family composition. Eligible patients for IVF treatment must be Ontario residents under the age of 43 and have a valid Ontario Health Insurance Plan card and have not already undergone any IVF cycles. Coverage is extensive, but not universal. Coverage extends to certain blood and urine tests, physician/nurse counselling and consultations, certain ultrasounds, up to two cycle monitorings, embryo thawing, freezing and culture, fertilisation and embryology services, single transfers of all embryos, and one surgical sperm retrieval using certain techniques only if necessary. Drugs and medications are not covered under this Program, along with psychologist or social worker counselling, storage and shipping of eggs, sperm or embryos, and the purchase of donor sperm or eggs.[151]
Anger, sadness, and anxiety are common among parents struggling to expand their family. "Having a child already doesn't make going through infertility any easier," says Alice D. Domar, Ph.D., executive director of the Domar Center for Mind/Body Health, in Waltham, Massachusetts, and author of Conquering Infertility. Meeting with a mental-health professional or seeking out blogs and online groups for secondary infertility can help. The website of the National Infertility Association, resolve.org, is a good place to start.
In the United States, women seeking to be an embryo recipient undergo infectious disease screening required by the U.S. Food and Drug Administration (FDA), and reproductive tests to determine the best placement location and cycle timing before the actual Embryo Transfer occurs. The amount of screening the embryo has already undergone is largely dependent on the genetic parents' own IVF clinic and process. The embryo recipient may elect to have her own embryologist conduct further testing.
Bloating: Fertility medications can heavily impact how your body retains water, leading to the dreaded side effect of bloating. This is especially common in your midsection, where fluid can build up near the ovaries (creating abdominal tenderness, too). You can combat bloating by increasing your fluid intake and participating in light exercise such as walking.
andisheh tv Apple bean Best Fertility Foods Boost comparing clinics dertility diet disorder DNA Dr. Berger dr joshua berger easy to make egg freezing exercise Exercise and pregnancy fertility fertility issues fertility preservation fertility treatment Health healthy Healthy Weight infertility infertility diagnosis infertility tests IVF lentil male male infertility maternal age men prevent skin sleep smoking sperm success rates Supplements unexplained infertility vitamin vitamin D Weight Loss Winter yogurt
Treatment with Clomid tablets plus IUI improves fertility rates. For unexplained infertility, studies have shown that for women under 35, monthly success rates for Clomid plus insemination are about 10% per cycle. This pregnancy rate holds up for about 3 tries and the success rate is considerably lower after that. More about success rates with IUIs is on the insemination page and on the Clomid for unexplained infertility page. The insemination component boosts fertility more than the Clomid does - but success rates are higher when both are used together.
A genetic disorder. If you or your partner is at risk of passing on a genetic disorder to your child, you may be candidates for preimplantation genetic testing — a procedure that involves IVF. After the eggs are harvested and fertilized, they're screened for certain genetic problems, although not all genetic problems can be found. Embryos that don't contain identified problems can be transferred to the uterus.
One of the biggest challenges is balancing enjoying the child you have with wondering if you'll ever get the larger family you want. "I watched my daughter take her first steps and thought, 'Maybe I'll never have this again,'"‰'' Bozinovich says. (Her problem was never pinpointed, but, happily, she went on to have two more children.) That is tough, the experts agree. "Worrying about what's happening next robs you of the pleasure of the moment," says Dr. Davidson. "It's not easy, but counseling and talking yourself through the rough moments can help you say, 'I'm doing the best I can, and meanwhile I'm living my life.'"‰"
Couples experiencing infertility have a range of treatment options. Women can take fertility drugs to stimulate ovulation, or undergo certain surgeries and procedures, like intrauterine insemination, which carefully places healthy sperm in the uterus right before an egg is released to increase the chances of fertilization. Men can also take fertility medication or undergo surgery to increase the chances of conception.
For many years, intrauterine insemination (IUI) was felt to be the best first choice of treatment in patients who have unexplained infertility or mild problems with the fallopian tubes or sperm. Arizona Reproductive Medicine (ARMS) has made significant advances in the cost effectiveness of in vitro fertilization (IVF) through higher IVF success rates and innovations in treatment medications and efficiency. IVF now far exceeds IUI as the best first choice of treatment for all age groups.
Problems with the uterus: There are many conditions related to the uterus that can cause secondary infertility. Scarring can occur during a dilation and curettage (D&C) or Cesarean delivery that can create adhesions inside the uterus that interfere with future pregnancies Fibroids or polyps are benign (non-cancer) growths inside the uterus that can impair pregnancy. A retained placenta can cause infection and uterine scarring.
The treatment options for unexplained infertility are several and the treatment results are promising. Expectant management can be recommended if the woman is under 28-30 years of age and the infertility duration is less than 2-3 years. In vitro fertilization (IVF) has revolutionized the treatment of infertile couples, as well as profoundly increasing the basic understanding of human reproduction. IVF can be used as both a diagnostic and a therapeutic tool in couples with unexplained infertility. The pregnancy rates with IVF are good, at 40% per treatment cycle. In addition, the outcome of pregnancies among women with unexplained infertility is generally comparable to that of spontaneous and other pregnancies using assisted reproductive technologies.


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After years of consideration I've come to the conclusion that, within limits, gear is more important as a topic of conversation than as a way of making music. It's just not that important - Chris Smither
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Noetic presented the findings to my senior management not long ago. We were delighted to have the consensus and buy-in around the core concepts of data management. As you put it, without being "involved in the day to day", its hard to explain the difficulty of getting people of the same page or even educated enough to voluntarily join the DG movement. Noetic advanced our business strategy and won over our technology teams – who initially were skeptical of using consultants for such a critical strategic function.
The data program looks really good, due to the contributions from Noetic. Thanks to you and your team.
Noetic Partners is a cut above the competition in cutting edge innovation for data management in the highly technical space of financial analysis. They are committed to excellence in customer service and finding the right value for customers. Building and keeping long term relationship with clients and seeing them through today's challenging environment of high competition and and economic austerity, Noetic Partners is a true partner in strategic execution.
FHFA has been concerned about data quality issues for a long time. The benchmark report that Justin and his team have prepared is a leap forward in gaining critical visibility into this issue. Their well thought-out, systematic and deliberate approach to this project has resulted in more progress on this issue - I think I can say without exaggeration - in the last year than we have seen in all the previous years combined. Who knows, maybe in the future data quality will be a component in loan pricing. The work they are doing has given a significant push towards best practices in the area of data quality.


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The Southern District of Indiana recently entered summary judgment against a certified class of TCPA plaintiffs because it concluded that defendants' SoundBite platform did not qualify as an ATDS under the standard the Seventh Circuit recently established in Gadelhak v. AT&T Services, Inc., 950 F.3d 458, 460 (7th Cir. 2020). Lanteri v. Credit Prot. Ass'n, L.P., No. 13-cv-01501, 2020 WL 3200076, *8 (S.D. Ind. June 15, 2020). Our previous coverage of Gadelhak can be found here. The Lanteri v. Credit Protection Association, L.P. decision illustrates that Gadelhak provides defendants facing TCPA claims in the Seventh Circuit with strong defenses to ATDS allegations.
Category Archives: Automatic Telephone Dialing System
Supreme Court Agrees To Review ATDS Definition
Earlier today, the United States Supreme Court granted the petition for certiorari in which Facebook had asked the Court to resolve the growing circuit split regarding the definition of an ATDS. The Court limited its review to the second question presented, namely "whether the definition of ATDS in the TCPA encompasses any device that can 'store' and 'automatically dial' telephone numbers, even if the device does not 'us[e] a random or sequential number generator.'" This comes hot on the heels of the Court's ruling earlier this week on the constitutionality and severability of the government-debt exception to the statute's restrictions on automated telephone equipment.
Supreme Court Strikes Government-Debt Exception But Saves Other Restrictions on Automated Telephone Equipment
On July 6, 2020, the Supreme Court issued a highly anticipated—and highly fractured—ruling in Barr v. American Association of Political Consultants. The nine Justices produced four opinions, none of which commanded a majority. But six of the Justices agreed that the TCPA's government-debt exception violated the First Amendment, and seven agreed that it could be severed from the rest of the TCPA. The result, then, is that the exception was stricken but the restrictions on automated telephone equipment were saved.
Writing for the plurality, Justice Kavanaugh made quick work of the government's argument that the exception was content-neutral: "A robocall that says, 'Please pay your government debt' is legal. A robocall that says, 'Please donate to our political campaign' is illegal. That is about as content-based as it gets." Because the exception was content-based, the plurality applied strict scrutiny—a standard that the government had conceded it could not satisfy.
Court Enters Summary Judgment Against Plaintiff, Finds No Triable Issues Regarding Revocation of Consent
The Eastern District of California recently entered summary judgment against a plaintiff because it found that the plaintiff failed to revoke his consent to receive auto-dialed calls on his cell phone. Wright v. USAA Savings Bank, No. 19-0591, 2020 WL 2615441, at *1-5 (E.D. Cal. May 22, 2020). The case illustrates that defendants in the Ninth Circuit can still prevail on consent and other issues even though they may face an uphill battle on ATDS issues.
The plaintiff in Wright applied for a credit card and listed his cell phone number on the application. Id. at *1. He developed terminal cancer in 2018 and failed to make payments on the credit card. Id. Between July 2018 and January 2019, defendants' agent called Mr. Wright's cellphone number using the Aspect Dialing System to collect the credit card debt. Id. Evidence established that the Aspect Dialing System is a predictive dialer that does not have and is not capable of using a random or sequential number generator to dial numbers. Id.
Southern District of Florida Court Holds that TCPA Plaintiff is Not the "Called-Party" Due to Call Forwarding
A court in the Southern District of Florida recently held that the plaintiff in a TCPA suit was not the "called party" under the statute because he received the calls in question only because his cousin rerouted them to the plaintiff's phone. Thompson v. Portfolio Recovery Associates, LLC, No. 19-62220 (S.D. Fla. Apr. 25, 2020).
In Thompson v. Portfolio Recovery Associates, LLC, Plaintiff Andrew Thompson brought a TCPA suit against PRA—a debt collection company—for seventeen calls made to the Plaintiff's cousin's VoIP number that were automatically rerouted by the Plaintiff's cousin to Plaintiff's phone and answered by Plaintiff.
District of New Jersey Adopts Narrow ATDS Definition as Circuit Split Grows; Supreme Court Clarification Required
As readers of this blog know, a robust Circuit split has developed regarding the meaning of an ATDS. The Second and Ninth Circuits have taken one approach, while the Third, Seventh, and Eleventh Circuits have taken another. While we await Supreme Court guidance, lower courts continue to grapple with the ATDS issue. In Eisenband v. Pine Belt Automotive, Inc., No. 17-8549 (FLW) (LHG), 2020 WL 1486045 (D.N.J. Mar. 27, 2020), the District of New Jersey analyzed the definition of an ATDS and concluded that equipment that dials numbers from a manually prepared list does not constitute an ATDS.
Supreme Court Holds Oral Argument via Teleconference in Barr v. American Association of Political Consultants
On May 6, 2020, the Supreme Court held oral argument via teleconference in Barr v. American Association of Political Consultants. The argument focused on the two questions presented in Barr. First, whether the Telephone Consumer Protection Act's (TCPA) government debt exception is an unconstitutional content-based restriction on speech. And second, if the government debt exception is unconstitutional, whether the remedy is to sever the exception or instead strike the TCPA's restrictions on automated telephone equipment in their entirety. A recording of the argument is available below (audio begins at the :30 mark) and a transcript is available on the Supreme Court website.


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Apple Arcade
How 'Grindstone' Accidentally Avoided Being an Annoying Free-to-Play Game
The Apple Arcade standout is back with a huge update, including a daily mode, and we had a few questions for the game's developer.
Five Months In, Here's What Developers Think of Apple Arcade
While most developers seem happy, it's clear the service has a lot of room to grow in the future.
Five Months Later, Apple Arcade Hasn't Transcended its Splashy Launch
Apple's services had a bunch of incredible games to kick things off, but since then? Not much.
Trippy 'Manifold Garden' Will Break Your Brain in the Most Satisfying Way
The most fun I've had not understanding anything I'm doing since 'Antichamber.'
Some Apple Arcade Games Will Finally Let You Play Podcasts, Too
'Grindstone' will now let you listen to other audio sources while mindlessly slaughtering enemies.
'Indivisible' Isn't Just Fun to Play, It's Extremely Funny, Too
A hilarious script isn't the first thing you expect from a fighting game studio.
How a 14-Year-Old Designer Became Part of Apple's Splashy New Gaming Service
After being picked by Apple to attend the company's developer conference, he was given a chance to pitch them—and seized the moment.
'Ghost Recon: Breakpoint' Puts You On Both Sides of Grotesque U.S. Military Might
Is the immense power of the US Military to commit violence a good thing or a bad thing? Who could say?
One of Apple Arcade's Biggest Games is a Square Enix RPG That's Real Bad
'Various Daylife' is a different value proposition for Apple Arcade: feeling blessed you didn't waste money buying it.
'What the Golf' Is WarioWare With Frickin' Golf Clubs
It may technically be a "golf game," but 'What the Golf' does not care what you think it is. 'What the Golf' does what it wants, and it's one of this year's funniest games.
Apple Arcade Promises Games Anywhere and on Any Device. It (Mostly) Works.
It's not a seamless transition from an iPhone to an Apple TV, or from a touch-based interface to a controller. And cloud saves are a problem.
Waypoint Radio Discusses Gaming's Latest Subscription Service, Apple Arcade
When it comes to developers getting paid, we don't know what we don't know.


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Why I'd shun 25% faller Flowtech Fluidpower and buy this FTSE 100 rising star
The share price of hydraulic power product supplier Flowtech Fluidpower (LSE: FLO) fell by as much as 29% on Tuesday morning.
The sharp drop was triggered by a profit warning caused by contract delays and management guidance that "growth may be softening".
Lost profit
Delays to a £1.5m contract for the Thames Tideway project mean that this revenue will now slip into 2019. Operating profit is now expected to be "marginally below market expectations" this year.
Another surprise is that long-serving chief executive Sean Fennon has decided to retire this year, and will "relinquish his executive duties … with immediate effect". Mr Fennon will be succeeded by chief financial officer Bryce Brooks, so there should be no leadership vacuum. But I get the feeling that Mr Fennon's departure may have been rushed slightly.
Growing pains?
Today's half-year figures from Flowtech suggest to me that after a string of acquisitions, the group may be experiencing some growing pains.
Revenue rose by 65% to £56m as acquisitions added volume, but underlying operating profit only rose by 26% to £5.7m. This means that the group's operating margin fell from 13.1% to 10.1% during the period.
Alongside this, net debt has risen by 114% to £18m over the last year, mostly due to acquisition spending. Another concern is that customers are taking an average of almost six months to pay their bills, leaving a lot of cash tied up in the business.
The company says it is putting its acquisition programme on hold to focus on developing its corporate infrastructure. This sounds sensible and may explain why Mr Fennon is being replaced by his top bean-counter — a traditional choice when financial improvements are required.
Flowtech shares look cheap after today's fall, on about 7 times forecast earnings with a forecast yield of 5%. But I think there could be more bad news to come. I'd steer clear of this stock for now.
A rising star
The share price of FTSE 100 firm Ashtead Group (LSE: AHT) has doubled over the last two years. This equipment rental firm hires out gear to construction companies and industrial customers. It operates the A-Plant business in the UK, but 85% of revenue comes from the Sunbelt business in the USA.
Like Flowtech, Ashtead has been taking advantage of a fragmented market to make regular acquisitions and increase market share. The firm spent £145m on small acquisitions during the three months to 31 July. This helped to lift revenue by 22% to £1,047m and pre-tax profit by 23% to £274m.
Note how both revenue and profit rose by roughly the same amount. This shows that profit margins are holding up as the company expands. That's something I like to see.
Is it too late to buy?
The group would be exposed in the event of a slowdown in the booming US market. But the company reported "strong end markets" during Q1 and said that full-year profits are now likely to be ahead of expectations.
Analysts' are forecasting earnings of 165p per share for the current year. This puts the stock on a forecast P/E of 14, with a prospective yield of 1.6%. The yield is low due to cash flow being invested in growth. But debt is under control and this valuation doesn't look excessive to me.
I believe Ashtead could still be worth buying if you want exposure to the US economy.
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TA Instruments Nano DSC for biological thermal stability
The Nano DSC is a powerful thermal scanning instrument that utilises a 300 µL capillary cell design and solid-state thermoelectric temperature control.
The product is a powerful tool for measuring the biologic thermal stability of protein and other biological systems of clinical importance. Applications range from drug formulation optimisation to monitoring biomolecular stability and basic understanding of protein folding/unfolding. Nano DSC experiments are label-free direct measurements of biomolecular unfolding under native condition, and do not rely on fluorescence detection (intrinsic or extrinsic).
The device is designed for ultrasensitive measure of heat absorbed or released by dilute in-solution biomolecules as they are heated or cooled. The 300 µL capillary cell design, solid-state thermoelectric temperature control and easy cleaning ensure high sensitivity and data reproducibility for a wide variety of applications.
For more information: https://www.tainstruments.com/nanodsc/.
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Thermo Scientific RadEye PRD4/PRD-ER4 personal radiation detector
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In a year where media entities are seeking new ways to manage content remotely, Tedial is using its social channels to propose the configuration of its products to create a seamless hybrid cloud environment.
The Associated Press (AP) ENPS news production system team has partnered with workflow developer Latakoo to enable assignment tracking and file delivery across both company platforms.
EcoDigital has launched the eighth generation of its Diva Software Suite, which is designed to optimise digital content storage management and simplify complex environments.
IABM's prolific business intel unit has identified an accelerated rush to the cloud, triggered by the pandemic.
Broadcast technology specialist Mediagenix has revealed details of the latest developments in its WHATS'ON broadcast management platform.
Caringo has launched a new Swarm Cloud DR managed service, powered by Wasabi Hot Cloud Storage.
The widely welcomed advancements behind Continuous Loudness Control (CLC) are behind a new cooperation deal between IRT and German vendor DSPECIALISTS.
The Digital Television Group (DTG) fielded a strong speaking team for its webcast 'Live Sport: Are the Fans Driving Innovation?' It was fronted by Andy Brember, commercial director, sport at Kantar.
The first S12T Streamline OB van for the African continent has been delivered to Rwanda Broadcasting Agency (RBA).
IABM has now taken its popular IBC Future Trends Theatre concept online as The Future Trends Channel.
Finnish cable operator DNA has picked Edgeware's content processing platform, StreamBuilder, for the launch of its new IP-based DNA TV service.
Florence-based acoustic design specialist Studio Sound Service has recently completed the transformation of the personal studio of Italian film composer Federico De Robertis.
Lawo has released new software with additional options, functionality and security features for its line of radio mixing consoles, RAVENNA/AES67 mixing engines, and VisTool GUI Builder software.
ScheduALL, part of Net Insight, has released the SaaS solution, ScheduALL Evolution, for resource management and crewing.
Sencore's new ARD 3000 series of ATSC 3.0 receiver decoders is designed to enable users to decode one channel (ARD 3100) or four channels (ARD 3400) in a 1RU platform.
Cloud-based video software specialist M2A Media is supporting the expansion of the BritBox SVOD streaming service in Canada via Amazon Prime Video.
JP Delport has been appointed managing director of Broadcast Solutions UK, a subsidiary of German systems integrator Broadcast Solutions.
Mediapro Argentina has turned to Lawo for a comprehensive technical upgrade of its facilities.
Broadcast management technology company MEDIAGENIX has announced that it has signed the United Nations Global Compact intiative.
New features in Vela's Encompass and Luna Smart Loggers have driven extensive uptake of the compliance, monitoring, capturing, logging, and multiviewer products in the company's home market.
Video: In this week's Tech Expert, Rowan de Pomerai explains the technology behind interoperable master format (IMF) and its benefits in versioning and distribution.


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Armenia is one of the world's earliest nations. Throughout its thousands of years of history the Armenian people has managed to maintain its strong historical and cultural identity, in a region at the crossroads between Asia and Europe, a place of encounter and confrontation with neighbouring peoples to East and West.
From the 4th century onwards the spread of Christianity manifests itself principally in the country's architecture. An extraordinary flourishing of domed churches built from tufa blocks characterizes the early years of Christianity whereas from the 10th century and on, the country is littered with beautiful monasteries snuggling between the folds of remote valleys on the immense Armenian plateau.
Of the traces left by this ancient and dynamic people, its architecture is perhaps the most effective witness, enlightening the history and past life of the Armenian communities from the arrival of Christianity to the present day.