text:
The whitewashed walls of lime, the rustling of the leaves of the great olive trees, and the desire to share with their guests a little of their love for Spain, our two lovers of the day imagined a simple and natural wedding in Sevilla.
Seville was the perfect setting to bring together guests from New York and around the world, and they could enjoy an incredible environment like the Casa de La Judería hotel where the newlyweds were prepared, as well as the Hacienda Molinillos, where the Persian ceremony and the big party took place.
In this wedding, All the symbols and the essence of the deepest persian tradition were in . Total harmony with the surrounding landscape of Sevilla ..
The combination of dominant green colour and brown, the palm trees, the savage nature around gave a pure air sensation making this wedding just perfect .
The tables are decorated with colorful and original pretty little bouquets and pomegranate.
Wedding team:
Photographer: Ernesto Villalba // MUAH: Oui Novias // Flowers: La Galeria de Jesús Fuertes // Venue: Hacienda Molinillos


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Fast Stochastic
|Previous Close
|5.62 x 1300
|5.63 x 1100
|Day's Range
|5.61 - 5.81
|52 Week Range
|1.21 - 7.09
|Avg. Volume
|Market Cap
|Beta (5Y Monthly)
|PE Ratio (TTM)
|Earnings Date
|Aug 10, 2020
|Forward Dividend & Yield
|Ex-Dividend Date
|1y Target Est
Joining me on the call today are Sujal Shah, chief executive officer; Dr. Sujal will provide an update on recent progress and plans on the development program for seladelpar, as well as a brief summary of our financials before we open the call up for Q&A. Before we begin, I'd like to remind everyone that statements made during this conference call, including the Q&A session, relating to CymaBay's expected future performance, business prospects, events or plans, including clinical plans, regulatory approvals and anticipated time lines and data release dates and cash runway are forward-looking statements as defined under the Private Securities Litigation Reform Act of 1995. Although the company believes that the expectations reflected in such forward-looking statements are based upon reasonable assumptions, actual outcomes and results are subject to risks and uncertainties and could differ materially from those forecast due to the impact of many factors.
FDA lifts all clinical holds on seladelpar Positive topline data announced from ENHANCECompany to reinitiate clinical development of seladelpar for patients with PBCCash sufficient to fund current operating plan into 2022 Conference call and webcast today at 4:30 p.m. ETNEWARK, Calif., Aug. 10, 2020 (GLOBE NEWSWIRE) -- CymaBay Therapeutics, Inc. (NASDAQ: CBAY), a clinical-stage biopharmaceutical company focused on developing therapies for liver and other chronic diseases with high unmet need, today announced corporate updates and financial results for the second quarter and six months ended June 30, 2020. Specifically, in the second quarter and through early August 2020, CymaBay achieved significant progress in its ongoing efforts to review its strategic options, one of which included completing a scientific investigation and working with the FDA to lift the clinical holds on the seladelpar INDs in nonalcoholic steatohepatitis (NASH), primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), the three liver diseases in which CymaBay had terminated clinical studies late last year. Sujal Shah, President and CEO of CymaBay, stated, "We are thrilled with the significant progress made to date in our efforts to conduct a review of strategic options, one of which was to pursue the reinstatement of our seladelpar program. Specifically, in May, we convened a panel of expert liver pathologists and hepatologists that unanimously concluded after a thorough, independent investigation, that there was no clinical, biochemical, or histological evidence of seladelpar-induced liver injury for patients enrolled in our Phase 2b NASH study. We discussed the panel's findings and related information with the FDA and submitted complete responses to the agency, and in July, the FDA notified us that all clinical holds on seladelpar were lifted. In addition to this favorable outcome, we evaluated and announced last week positive topline results from our ENHANCE study of seladelpar in PBC which, despite being terminated early, provided sufficient data which appear to support seladelpar's efficacy and tolerability in this patient population. After receiving notification from the FDA, and reviewing the latest clinical data from the ENHANCE study, we stopped our review of strategic options having decided to focus on reinstating the clinical development program for seladelpar in PBC and to continue to evaluate seladelpar for other indications. We have also been very successfully at minimizing our operating expenses through the first half of the year and expect our cash to fund our current operating plan into 2022."Recent Corporate Highlights * In May 2020, a panel of eight of the world's foremost expert liver pathologists and hepatologists, whose collective experience relevant to CymaBay's investigation includes drug-induced liver injury, NASH and cholestatic liver diseases, completed a four-day independent review analyzing findings from CymaBay's NASH Phase 2b study, and the results of independent pathologist's reviews of the study biopsies, which included a blinded unpaired review and a paired review blinded to chronologic order of the biopsies. The panel unanimously supported lifting the clinical hold for seladelpar and re-initiation of clinical development pending approval by the FDA. In June 2020, CymaBay discussed the data and the panel's conclusions with the FDA and submitted complete responses to the agency. In July 2020, the FDA lifted clinical holds on seladelpar in all indications with open INDs (NASH, PBC and PSC). * In August 2020, CymaBay announced positive topline results from ENHANCE for seladelpar in patients with PBC. Topline data for patients through 3 and 6 months demonstrated anti-cholestatic, anti-inflammatory, and anti-pruritic activity. Notably, 78.2% of patients on seladelpar 10 mg versus 12.5% on placebo achieved the primary composite outcome after only 3 months (p<0.0001). In addition, 27.3% of patients on seladelpar 10 mg versus zero on placebo experienced normalization of ALP by 3 months (p<0.0001). Treatment with seladelpar 10 mg also resulted in a statistically significant improvement in pruritus (p<0.05) for patients with moderate-to-severe itch versus placebo. Overall, seladelpar appeared to be safe and well-tolerated in this study. * CymaBay intends to reinitiate the long-term study, a Phase 3 study and other NDA-enabling studies to confirm the potential of seladelpar to be a best-in-class treatment for patients with PBC and to further evaluate suitable strategies to advance seladelpar in other indications. * CymaBay held $168.9 million in cash, cash equivalents and short-term investments as of June 30, 2020 and had no outstanding debt. Cash and investments are deemed sufficient to fund CymaBay's current operating plan into 2022. * Due to the ongoing effects of the global coronavirus pandemic, CymaBay continues to conduct its operations remotely for all employees, which has allowed business activities to continue as seamlessly as possible. To date, these developments have not had a significant impact on CymaBay's financial condition or its ability to execute its business plan. CymaBay will continue to closely monitor pandemic developments and their associated risks to the business, including plans to restart clinical development of seladelpar, and will continue to take actions available to mitigate them where possible. Further, all CymaBay's actions will be guided by a commitment to taking all steps possible to ensure the health and safety of its employees as well as patients enrolled in its clinical studies. Second Quarter and Six Months Ended June 30, 2020 Financial Results * Research and development expenses for the three months ended June 30, 2020 were $7.9 million, compared to $21.1 million for the three months ended June 30, 2019. Research and development expenses for the six months ended June 30, 2020 were $17.5 million, compared to $39.7 million for the six months ended June 30, 2019. Research and development expense in the three and six months of 2020 was significantly lower than the corresponding periods in 2019 primarily due to declining clinical trial activities related to the Phase 3 PBC, Phase 2b NASH, and Phase 2 PSC clinical trials, and other studies, as efforts continued to shut down these studies which were early-terminated as a result of the FDA's clinical holds that were placed on the seladelpar program in the fourth quarter of 2019. * General and administrative expenses for the three months ended June 30, 2020 were $3.4 million, compared to $4.5 million for the three months ended June 30, 2019. General and administrative expenses for the six months ended June 30, 2020 were $7.7 million, compared to $10.2 million for the six months ended June 30, 2019. General and administrative expenses in the three and six months of 2020 were lower than the corresponding periods in 2019 due to lower employee compensation and other administrative expenses incurred as a result of a December 2019 reduction-in-force and restructuring effort that was undertaken to reduce costs in response to the FDA's clinical holds on the seladelpar program. * Net loss for the three months ended June 30, 2020 was $10.7 million, or ($0.16) per diluted share, compared to a net loss of $24.0 million, or ($0.35) per diluted share in the three months ended June 30, 2019. Net loss for the six months ended June 30, 2020 was $23.8 million, or ($0.35) per diluted share, compared to a net loss of $47.1 million, or ($0.72) per diluted share in the six months ended June 30, 2019. Net loss was lower in the three and six months of 2020 compared to the corresponding periods in 2019 primarily due to a decrease in operating expenses, including clinical trial and labor related expenses, as a result of the early-termination of our seladelpar studies and our cost reduction efforts undertaken in response to the FDA's clinical holds that were placed on the seladelpar program in the fourth quarter of 2019. Conference Call DetailsCymaBay will host a conference call today at 4:30 p.m. ET to discuss second quarter 2020 financial results and provide a corporate update. To access the live conference call, please dial 877-407-0784 from the U.S. and Canada, or 201-689-8560 internationally, Conference ID 13706143. To access the live and subsequently archived webcast of the conference call, go to the Investors section of the company's website at http://ir.cymabay.com/events.About CymaBay CymaBay Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for liver and other chronic diseases with high unmet medical need. CymaBay is developing seladelpar, a potent, selective, orally active PPARδ agonist for patients with primary biliary cholangitis (PBC). Seladelpar has received an orphan designation from the US Food and Drug administration (FDA) and the European Medicine Agency (EMA). Seladelpar also received Breakthrough Therapy Designation from the FDA and PRIority MEdicines status from the EMA for PBC.Cautionary StatementsAny statements made in this press release and accompanying conference call regarding the potential for seladelpar to treat PBC and potentially improve clinical symptoms of the disease, the potential benefits to patients, CymaBay's expectations and plans regarding its intended future interactions with the FDA, its current and future clinical trials and CymaBay's ability to fund current and planned clinical trials are forward looking statements that are subject to risks and uncertainties. Actual results and the timing of events regarding the further development of seladelpar could differ materially from those anticipated in such forward-looking statements as a result of risks and uncertainties, which include, without limitation, risks related to: the success, cost and timing of any of CymaBay's product development activities, including clinical trials; effects observed in trials to date that may not be repeated in the future; any delays or inability to obtain or maintain regulatory approval of CymaBay's product candidates in the United States or worldwide; and the ability of CymaBay to obtain sufficient financing to complete development, regulatory approval and commercialization of its product candidates in the United States and worldwide or to potentially restart clinical trials. Additional risks relating to CymaBay are contained in CymaBay's filings with the Securities and Exchange Commission, including without limitation its most recent Annual Report on Form 10-K and other documents subsequently filed with or furnished to the Securities and Exchange Commission. CymaBay disclaims any obligation to update these forward-looking statements except as required by law.For additional information about CymaBay visit www.cymabay.com.Public Relations Contact: Glenn Silver Lazar-FINN Partners (973) 818-8198 firstname.lastname@example.com Investor Relations Contact:Hans Vitzthum LifeSci Advisors, LLC (617) 430-7578 email@example.com CymaBay Therapeutics, Inc. Financial Results (In thousands, except share and per share information) Quarter Ended Six Months Ended June 30, June 30, 2020 2019 2020 2019 (unaudited) (unaudited) (unaudited) (unaudited) Operating expenses: Research and development $7,942 $21,119 $17,451 $39,707 General and administrative 3,398 4,529 7,745 10,192 Restructuring charges (188) - (117) - Total operating expenses 11,152 25,648 25,079 49,899 Loss from operations (11,152) (25,648) (25,079) (49,899) Other income: Interest income 426 1,610 1,265 2,786 Total other income 426 1,610 1,265 2,786 Net loss $(10,726) $(24,038) $(23,814) $(47,113) Basic net loss per common share $(0.16) $(0.35) $(0.35) $(0.72) Diluted net loss per common share $(0.16) $(0.35) $(0.35) $(0.72) Weighted average common shares outstanding used to calculate basic net loss per common share 68,885,108 68,697,735 68,883,783 65,312,988 Weighted average common shares outstanding used to calculate diluted net loss per common share 68,885,108 68,697,735 68,883,783 65,312,988 CymaBay Therapeutics, Inc. Balance Sheet Data (in thousands) June 30, December 31, 2020 2019 (unaudited) Cash, cash equivalents and marketable securities $168,907 $190,945 Working capital 164,624 185,287 Total assets 176,597 205,727 Total liabilities 10,989 19,379 Common stock and additional paid-in capital 815,108 812,140 Total stockholders' equity 165,608 186,348
The "dog days" of summer are here, but it's just as busy as ever on the Street. As earnings results continue to roll in, investors will be watching for any update on the next economic stimulus package along with the non-farm payroll report slated for release this Friday. Against this backdrop, plenty of questions remain, weighing on the minds of both institutional and private investors.In a recent note to clients, Oppenheimer's Chief Investment Strategist John Stoltzfus addresses these concerns. When it comes to stocks' disconnected state, he writes that the market tends to focus on the future, with it betting on a successful outcome based on the stimulus policy already put in place. But will this highly accommodative monetary policy eventually cause inflation?"We do not expect high levels of inflation to result from the extraordinary stimulus and monetary policy taken to deal with the Covid-19 pandemic. Federal Reserve vigilance against inflation (as well as vigilance by central banks around the world) is likely to be able to suitably address any flare up of inflation," Stoltzfus commented.Bearing this in mind, we took a closer look at three stocks backed by the analysts at Oppenheimer, the third best-performing research firm, according to TipRanks. Running the tickers through TipRanks' database, we learned Oppenheimer sees at least 120% upside potential in store for each, and all three have earned a "Strong Buy" consensus rating from the rest of the Street.Durect Corporation (DRRX)Developing innovative therapies based on its endogenous epigenetic regulator program, Durect believes it could potentially transform the treatment of acute organ injury and chronic liver diseases. As one of its candidates has delivered encouraging results, Oppenheimer sees an opportunity to get in on the action.Firm analyst Francois Brisebois recently told clients, "After several years of promising results, we believe DRRX's endogenous small molecule epigenetic regulator DUR-928 has finally found its home in the treatment of Alcoholic Hepatitis (AH). Given a high level of mortality (26% 1-month rate) and no viable treatment options, we believe DUR-928's fairly early robust Phase 2a efficacy and safety data could have it attacking this ~ $3 billion market opportunity with peak penetration as early as 2025."Digging a bit deeper into this Phase 2a data, along with a robust safety profile, the trial showed that the therapy was able to rapidly reduce bilirubin, a marker of AH. In addition, there was a 100% response to treatment from the Lille score (mortality predictor tool) in 30mg and 90mg dosages and reduction in MELD (AH severity). Going forward, AH Phase 2b is set to begin in 2H20. "Given the potential to receive Breakthrough Therapy Designation (BTD) for treating a life-threatening condition with a substantial improvement over available therapies (mainly corticosteroids), launch could happen ahead of anticipation. Additionally, market exclusivity and pricing could be greater if Orphan Drug Designation (ODD) is awarded based on ~117,000 annual hospitalizations," Brisebois added.Plenty of other catalysts are still ahead, in Brisebois' opinion. DUR-928 is being evaluated in hospitalized COVID-19 patients with acute liver or kidney injury in a Phase 2 study and Phase 1b NASH data could be released during an upcoming conference. It should also be noted that it's a "waiting game" for Posimir's PDUFA, with the analyst considering "any related weakness as a buying opportunity."All of the above makes Brisebois optimistic about DRRX's long-term growth prospects. As a result, the analyst continues to assign an Outperform rating and $7 price target to the stock. Should his thesis play out, a potential twelve-month gain of 202% could be in the cards. (To watch Brisebois' track record, click here) Brisebois' colleagues are also pounding the table on DRRX. Only Buy ratings, 4, in fact, have been issued in the last three months, so the consensus rating is a Strong Buy. At $6, the average price target implies shares could climb 156% higher in the next year. (See DRRX stock analysis on TipRanks)Avadel Pharmaceuticals (AVDL)Hoping to address overlooked and unmet medical needs, Avadel Pharmaceuticals wants to provide solutions through its patient-focused and cutting-edge products. With Oppenheimer stating its asset has "disruptive potential in a proven blockbuster market," the firm believes it might be time to snap up shares. According to analyst Francois Brisebois, who also covers DRRX, AVDL is primarily focused on FT218, a once-nightly sodium oxybate designed for the treatment of narcolepsy patients suffering from excessive daytime sleepiness (EDS) and cataplexy. He goes so far as to call the candidate the company's "first, second and third priorities," noting that it recently sold its Hospital Drug Portfolio "to avoid distractions."Looking at the pivotal Phase 3 REST-ON top-line data, Brisebois believes it "speaks for itself." At the 9g dose, FT218 was able to produce a change from baseline in Maintenance of Wakefulness (MWT) of 10.82 minutes vs. 4.469 in placebo, in Clinical Global Impression-Improvement (CGI-I) of 72% vs. 31.6% and in Mean Weekly Cataplexy Attacks of -11.51 vs. -4.86, all three of the co-primary endpoints. "We were particularly impressed that the 6g and 7.5g doses also showed p<0.001 across all co-primary endpoints," the analyst added.The implication? "Following strong efficacy and safety data, we believe FT218 could significantly disrupt Jazz Pharmaceuticals' Xyrem (twice-nightly sodium oxybate), which reported FY19 sales of $1.6 billion," Brisebois said.While some investors have expressed concern regarding the company's freedom to operate, Brisebois isn't too worried. "We are comfortable with AVDL's freedom to operate path forward as we don't believe it will infringe on Xyrem's IP (REMS or DDI). Although FT218 does use the same drug substance, it consists of a substantially different drug product. The label should add more clarity," he explained.Additionally, management has made a significant effort to drive a turnaround. Brisebois points out that since CEO Greg Divis was appointed in June 2019, he has offered clear guidance on enrollment, which has led to huge gains in the share price. He also mentioned, "Dr. Jordan Dubow's appointment as CMO was key because of his important role in adjusting the original study design (data a year ahead of expectations). New CFO Thomas McHugh's commercial experience is crucial."Given everything that AVDL has going for it, it's clear why Brisebois joined the bulls. In addition to initiating coverage with an Outperform rating, the analyst put a $19 price target on the stock. What does this mean for investors? Upside potential of 134% is at play.Overall, the bulls take the lead on this one. Out of 5 total reviews published in the last three months, all 5 analysts rated the stock a Buy. Therefore, the message is clear: AVDL is a Strong Buy. The $18.40 average price target implies shares could skyrocket 126% in the next twelve months. (See Avadel stock analysis on TipRanks)CymaBay Therapeutics (CBAY)Last but not least we have CymaBay Therapeutics, which develops therapies designed to improve the lives of patients with liver and other chronic diseases. Given its impressive technology, Oppenheimer has high hopes.Covering the stock for the firm, analyst Jay Olson points out that its seladelpar asset produced strong results in the ENHANCE Phase 3 study in PBC. As it was terminated early and there were only a small number of patients that reached 12 months, the primary endpoint was changed to 3 months. The revised primary composite and key secondary ALP normalization endpoints were both statistically significant at 10mg. "We believe these impressive efficacy results could set a new paradigm for physicians and patients as they strive to achieve ALP normalization," the analyst commented.Going into more detail, 30% of patients in the study had moderate-to-severe pruritus, and the pruritus levels were balanced and representative of high-risk PBC patients, in Olson's opinion. Unlike Ocaliva, which has a warning for severe pruritus with management strategies that include temporary dosing interruption, seladelpar was able to generate a substantial improvement in pruritus.Based on this promising data, CBAY could kick off a Phase 3 PBC study. "We expect CBAY to initiate this simplified Phase 3 PBC trial in 1Q21 with 12-month primary endpoint for pivotal data in 2023. The safety profile of seladelpar is similar to placebo and compares favorably to Ocaliva's which has a boxed warning for dosing in certain patients," Olson stated.When it comes to the NASH indication, Phase 2b 52-week biopsy data, which showed a solid reduction in fibrosis and NASH resolution, could support seladelpar's progression to Phase 3. It should be noted that CBAY might seek a partner here.With the company boasting a path forward in 2L PBC that could establish seladelpar as the standard of care, the deal is sealed for Olson. To this end, the analyst rates CBAY an Outperform (i.e. Buy) along with a $12 price target. This figure suggests 127.5% upside potential from current levels. (To watch Olson's track record, click here) Looking at the consensus breakdown, other analysts echo Olson's sentiment. With 8 Buys compared to no Holds or Sells, the word on the Street is that CBAY is a Strong Buy. In addition, the $12 average price target is identical to the Oppenheimer analyst's. (See CBAY stock analysis on TipRanks)To find good ideas for healthcare stocks trading at attractive valuations, visit TipRanks' Best Stocks to Buy, a newly launched tool that unites all of TipRanks' equity insights.Disclaimer: The opinions expressed in this article are solely those of the featured analysts. The content is intended to be used for informational purposes only. It is very important to do your own analysis before making any investment.

subset: commoncrawl


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Iq Options 2020 Otc España
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Debit card number and cvv
Follow the steps below to get started with generating pawn unique Visa credit cards number. You can quickly generate the Visa card information using vccgenerator. It generates
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Автор: vaudi777 | Опубликовано: 18 Apr 2020
Теги: cvv, number, card, debit | Категория: dump shop
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Colm Lindsay Cars Ltd
Family Run New & Used Car Sales located in Newry Co. Down and Carlingford Co. Louth established 1989
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Adam's Christening Photographs
Adam's Christening Photographs
And the canvas which was ordered of Adam –
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Hi Sam, Please thank Douglas for doing an amazing job! We love the pictures, he has managed to capture all the kids brilliantly! We will probably want to have a professional album made – seems half a job to do it myself with sticky tabs! Thanks again, Helen


text: Footfall to Italy\u2019s hospitality sector has hit 90% of pre-lockdown levels, as appetite for the country\u2019s restaurants, cafes and bars continues to grow. Hospitality in Italy saw a bigger rise in footfall than any of its European counterparts following the easing of lockdown measures at the start of May and this steady upward trend has reached record highs in the last week. Huq\u2019s Key Industries Indicator, which also measures footfall to supermarkets, hotels and transport, also shows an encouraging uplift in hotel attendance in the last three weeks, with physical attendance increasing by 18pts to 47% of pre-lockdown levels. While hotels have seen notable rise in footfall recently, use of public transport remains low, suggesting that people are still avoiding buses, trains and plans - perhaps treating themselves to a hotel stay more locally. The data, which uses pre-Covid levels as a base, suggests that the recovery of hospitality in Italy is now outpacing supermarkets - an interesting parity between these discretionary and staple sectors. Footfall across supermarkets is now sitting at around 80% of pre-lockdown levels. Following Boris Johnson\u2019s announcement yesterday that UK pubs, restaurants and hotels will be allowed to open from 4 July, there are hopes that the sector in the UK will enjoy similar release of pent-up demand. Although Brits might have to order a pint in advance and keep their distance from other punters, visits to Italy\u2019s pizzeria\u2019s and cafes in the last week offer a glimpse of just what could be. Huq\u2019s Indicators can help analysts better understand what a recovery from Covid-19 will look like. If you would like to measure activity on a particular location, industry or subject that is not already contained within Huq's Indicator catalogue, please get in touch with our new business team to discuss your requirements.\u00a0


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The Mission of the Western Magic Valley REALTORS® is to support it's members in their business pursuits by promoting the highest professional standards ethics and being the primary provider for quality services, education and real estate services in our market area. WMVR has over 500 REALTOR® members and an increasing number of Affiliates.
Western Magic Valley REALTORS® has the honor of organizing this year's REALTOR® Fun Run/Walk! This event will focus on raising awareness of the dangers involved in the Real Estate Profession. All proceeds go to benefit the Beverly Carter Foundation. Beverly was a REALTOR® in Arkansas who was murdered showing homes.
We offer Pre-license Classes!
To learn more, click the link below.
See what's new with WMVR! Pertinent information you need to know.
Good Morning WMVR, I will be sharing these emails weekly. Due to State Law & social distancing guidelines it has been very difficult to safely host large events such as Luncheons & RPAC events. WMVR is postponing all large events until we can comply with laws and do so safely for everyone. We will be […]
Good Morning WMVR, I hope everyone had a wonderful & SAFE Independence Day! Due to recent increase in COVID-19 cases and to keep everyone safe and healthy we will be hosting our July General Membership Meeting Virtually. For a lot of great content and all past articles check out our blog: https://wmvrealtors.com/2020/04/ryans-stream/. WMVR General Membership […]
Realtor Safety is VERY Real. Please read the newsletter from the Beverly Carter Foundation. https://newsletter.homeactions.net/archive/newsletter/13482/11707096/2137903 Remember, Realtor Safety Month is coming in September.
These Affiliates and Sponsors have stepped up financially to support our Association. Please think of them FIRST if you or your clients need any of the services we offer.
Call the Board Office (208) 733-6421
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Journal of Veterinary Clinics (한국임상수의학회지)
- Volume 18 Issue 3
- /
- Pages.293-296
- /
- 2001
- /
- 1598-298X(pISSN)
- /
- 2384-0749(eISSN)
Hepatic encephalophthy was diagnosed with serum chemistry, abdominal radiography and ultrasonography in a 2.6kg, 4 year-old maltese dog showing signs of hypersalivation, involutary spasm of facial muscles, ataxia, behavior abnormalities like dullness, sleep disorder, restlessness. In serum chemistry, the level of alanine transferase and aspartate trasferase was mildly elevated, ammonia was severely increased. On abdominal radio-graphs, the size of liver was mildly decreased. In ultrasonographic examination, diffuse lesion with hyperechoic change and decreased vasculature were seen in the hepatic region. But vascular abnormalities of liver were not observed. Drug and dietary therapy were undertaken and severities of clinical sign were alleviated.
- Clin Sci v.67 Supersensitivity of benzodiazepine receptors in hepatic encephalopathy due to fulminant hepatic failure in the rat: Reversal by a benzodiszepine antagonist Baraldi M;Zeneroli ML;Ventura E;Penne A;Pinelli G;Ricci R;Santi M
- J Vet Intern Med v.7 A retrospective study of 77 cats with severe hepatic lipidosis,1975-1990 Center SA;Crawford MA;Guida L;Erb HN;King J
- Semin Vet Med Surg v.5 Liver function test in the diagnosis of portosystemic vascular anomalies Center SA
- Hepatic Encephalopathy: Management with Lactulose and Related Carbohydrates Conn HO;Bircher J
- Textbook of small animal internal medicine(5th ed.) History, Physical Examinaon, and Signs of Liver Disease Jan Rothuizen;Hein P. Meyer:Ettinger SJ(ed.)
- Yale J Biol Med v.57 Pappas SC: The GABA hypothesis of the pathogenesis of hepatic encephalopathy: Current status Jone EA;Schafer DF;Ferenci P
- Small animal internal medicine(2nd ed) C. Guillermo couto: Clinical Manifestation of Hepatobilliary Disease Richard WN
- JAVMA v.166 Freedland RA: Hyperammonemia due to a urea cysle enzyme deficiency in 2 dogs Strombeck DR;Meyer DJ
- Br Med J v.218 Flumazenil: A benzodiszepine antagonist Whitwam JG


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Take home these vibrant lights and light-up your abode magnificently. The lights, equipped with a lamp lock facility, make them replaceable, interchangeable, and keep them from falling out. Everyone is sure to praise you for the excellent lighting.
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Color: red and pure white bulbs / white wire
Number of bulbs on string: 50
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12" lead cord
3" tail cord
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LED lights use 90% less energy
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UL certified and approved for indoor or outdoor use
If one bulb burns out, the rest will stay lit
Lights are equipped with Lamp Lock feature, which makes them replaceable, interchangeable and keeps them from falling out
Comes with replacement bulbs and spare fuses
Contains end-to-end connectors which allows you to connect multiple sets together (not to exceed 210 watts)
Connect up to 87 sets end to end
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120 volts, 60 hertz, 0.02 amps, 2.4 watts
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- UL certified and approved for indoor or outdoor use
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Product Dimensions: 1.00"H x 1.00"W x 210.00"D


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August 7, 2020
Emery N. Koenig is on the board of CARE USA, Catholic Community Foundation, The Mosaic Co. and Catholic Community Foundation (Texas) and Treasurer & Trustee at Minnesota Public Radio.
In his past career he occupied the position of Vice Chairman & Chief Risk Officer at Cargill, Inc. and Treasurer & Trustee at American Public Media Group.
Mr. Koenig received an undergraduate degree from the University of North Dakota.


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Grovetown family movie night delayed until August
Published: Jul. 31, 2020 at 12:27 PM EDT
GROVETOWN – The date of a "Family Movie Night at the Park" has been changed due to weather concerns.
Earlier planned for tonight, the event will now be Aug. 21 at the Liberty Park Community Center, 1040 Newmantown Road in Grovetown.
The film "How to Train Your Dragon: The Hidden World" will be shown at dark. Participants should bring their own chairs and blankets. Vendors will sell food and snacks during the movie.
The cost is $5. Register online at https://secure.rec1.com/GA/grovetown-ga/catalog.
Copyright 2020 WRDW/WAGT. All rights reserved.


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Open house Tullinge
Welcome to our home! It was built indesigned in a national romantic style. It is located in Tullinge, a friendly suburb 20 km south of Stockholm.
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Why am I seeing this?]Our home was built in and has been carefully renovated. It is situated in a quiet area in Tullinge, just outside of Stockholm, Tullinbe for families and couples.
The house has a large glass porch and a green garden with cosy sittning areas, a trampolin and a playground for children. Open house Tullinge house has four bedrooms. We have three bathrooms. Also there is a spacious glass veranda, a living room and a TV-room.
We Open house Tullinge a high speed internet connection and wifi Netflix, Xbox. Tullinge is great if you wish Being a black woman in Ystad combine city life in Stockholm with it's restaurants, museums and shopping with recreational activities such as visiting the beautiful archipelago of Stockholm, go swimming in one of the nearby lakes or hiking in the great Lida preserve.
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This is an incredible, grand 3 bedroom flat situated over 2 floors, benefiting from stunning room sizes and planning permission to extend.
Key features
- Unique and grand three bedroom duplex apartment
- Impressive double reception with high ceilings
- Bespoke kitchen with space to entertain and dine
- High specification integrated appliances
- 3 double bedrooms, all with fitted wardrobes and en suites
- Terrace and patio garden
- Fantastic location close to Hyde Park
- Planning PP/14/07764 to extend by approximately 165 sq ft
My notes
(maximum length of note is 256 characters)
Further details
- Tenure:
- Leasehold plus share of freehold
- Lease expires:
- Mar 3010
- Ground rent:
- Peppercorn
- Service charge:
- £7000 per annum (2020)
- Stamp Duty
- £240,750
- Council tax:
- £2,474 per year (Band H)
- Local authority:
- The Royal Borough of Kensington and Chelsea
- Total Sq Ft:
- 1,964 (182 Sq M) approx.
- Reference:
- 186064
Lease details, service charges, ground rent (where applicable) and council tax are given as a guide only and should be checked and confirmed by your Solicitor prior to exchange of contracts.
Calculations by Alexander Hall Mortgages
Nearest stations
Gloucester Road station
Piccadilly District Circle lines, Zone: 1
South Kensington station
Piccadilly District Circle lines, Zone: 1
High Street Kensington station
District Circle lines, Zone: 1
Energy Performance Certificates
The Energy Performance Certificate (EPC) gives the building a standard energy and carbon emission efficiency grade from 'A' to 'G', where 'A' is the most efficient and 'D' being the average to date.
Local Life
Elvaston Place is a prestigious residential street moments from the shops and restaurants of Gloucester Road. The nearest underground station is Gloucester Road (Piccadilly, District and Circle lines).
South Kensington locals have kindly shared their favourite places to go...
The V&A
With over 4.5 million items in its collection, The Victoria and Albert Museum is a celebrated part of London's cultural heritage.
The Royal College of Music
Prestigious classical music school established by royal charter in 1882.
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Andreea Mantea she can not stop expressing her love and care for her little one, David Andrei.
Because during this period she found the strength to fight in her virtual friends and family, Andreea Mantea does not forget to share pictures from the most intimate and special moments in her life.
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Also read Andreea Mantea knows an entire country, but the star̵


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by John Pierson ‧ RELEASE DATE: Jan. 25, 1996
An insider's nuts-and-bolts dissection of the gritty machinery of independent film financing and distribution. The modern ""indie"" film movement was born in 1984 with Jim Jarmusch's Stranger Than Paradise, which proved with the force of a revelation that an important, good-looking movie could be made for less than $100,000. Directors began to compete over who would do the most with the lowest budget, with Richard Rodriguez's $7,000 El Mariachi the bargain-basement winner. But no film that makes it to the local multiplex really costs so little. El Mariachi, for example, required more than $100,000 just for reworking the sound. The lowball budgets were just to get the film ""in the can,"" so that it could be shown to someone like John Pierson. While Pierson has produced a few films, the niche he carved for himself was providing finishing money for films and then, as a ""producer's rep,"" finding a distributor--crucial if a film is ever to have a theatrical run and get proper publicity. Over the last ten years, from Roger and Me to The Thin Blue Line and Slacker, there were few independent films he wasn't somehow involved with. In Hollywood terms the money at stake was chump change--less than might be spent on Demi Moore's entourage--but the 15-plus films Pierson helped were, almost without exception, quirky, provocative, utterly original, and could never have been made in Hollywood. With a swashbuckler's zest, Pierson recounts his various deals and machinations (usefully documented by budgets and deal memos) as he fought to get the filmmakers--and himself--the best possible deal. He also takes pains to note that most independent films are never distributed, languishing instead in the uncinematic darkness of the director's basement--$20,000 worth of celluloid playing only to the plaudits of dust. While the specialized nature of the material will probably limit its general appeal, this book should be required reading for all would-be filmmakers.
Pub Date: Jan. 25, 1996
Page Count: 352
Publisher: Miramax/Hyperion
Review Posted Online: N/A
Kirkus Reviews Issue: Dec. 15, 1995
Categories: NONFICTION
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This bill modifies the Test Cashing and Deferred Deposit Lending Registration Act to handle deferred deposit loans. This invoice: modifies definition provisions; addresses reporting necessities for deferred deposit lenders; imposes requirements associated to querying the database to determine ineligibility to obtain a deferred deposit loan; imposes necessities related to the commissioner's annual report; establishes what constitutes ineligibility to acquire a deferred deposit mortgage; creates the Deferred Deposit Lending Database Program, which includes the creation of the Deferred Deposit Lending Database; permits the department to contract with a 3rd party to establish and maintain the database; addresses numerous requirements associated to the operation of the database; grants rulemaking authority; gives for the process to make a question to the database, together with the cost of a fee; and makes technical and conforming amendments.
Wayne Coons felt a sense of panic when he realized that the $350 payday loan he obtained over the Internet was costing him a whole lot of dollars greater than he thought. Prohibits any person from partaking in the enterprise of making payday loans to any client residing within the commonwealth.
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Floral Glass Beaded Waterfall Necklace from Mexico, "Beautiful Rain"
Coming Back!
This item is available for backorder and will ship within 2 to 8 weeks. Read more
Pre-Order Now!
This item is available for pre-order and will ship within 2 to 8 weeks. Read more
Handcrafted of petite glass beads in a traditional style, beautiful flowers in a variety of colors rain from this waterfall necklace from Mexico. Adriana Trejo designs and crafts this accessory. It circles the wearer with black beads, completed by a button clasp and extender.
- 50 grams
- 0.1 lbs
- 43 cm L x 0.3 cm W
- 17" L x 0.1" W
- Pendant(s): 23 cm L x 3 cm W
- Pendant(s): 9" L x 1.2" W
- Extender: 3 cm L x 0.6 cm W
- Extender: 1.2" L x 0.2" W
Gift Info
- Email this item in advance of a gift.
- Email this item as a gift suggestion.
- Free Jewelry Packaging? Yes
- Premium Jewelry Gift Box? Yes
Reviews by Customers
"Beautiful Earrings!"
Such lovely earrings! Please see my review of Huichol Blue bracelet as I ordered these items together and again was not disappointed! Thank you!
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Purchased Item:
Sweet Star Flowers, Glass Beaded Floral Dangle Earrings from Mexico
"Outstanding Quality"
Ordered more items from this talented artist and was certainly not disappointed. Adore this beautiful bracelet and again was happy to find the same careful, thoughtful packaging with the personal note of thanks in Spanish and English. Thank You, Adriana and Debora.
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Purchased Item:
Huichol Blue, Floral Glass Beaded Wristband Bracelet from Mexico
"Outstanding Quality"
These gorgeous earrings made my day and customers should not hesitate to purchase from this very talented artist. Please see my review of Eagle Flight bracelet, as I ordered these beautiful items together. So appreciate Adriana Trejo--thank you!
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Purchased Item:
Afternoon Serenity, Handcrafted Glass Beaded Waterfall Earrings from Mexico
"ring to match necklace"
I love it when I can match a previously purchased piece of jewelry. Huichol never fails to turn heads and win complements. And the colors are always uplifting.
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Purchased Item:
Floral Colors, Glass Beaded Floral Cocktail Ring from Mexico
"unique and very well done"
Love this. So unusual. This is talent.
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Purchased Item:
Fantastic Frida, Frida-Themed Glass Beaded Pendant Necklace from Mexico
Verified Reviewer
"My second pair from this artist!"
I am amazed by how perfectly crafted these earrings are. I love the colors, the detail and also, they are so light. Lovely!
Best Uses
- Casual or formal
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Your Purchase Makes a Difference!
The Women's Empowerment badge is awarded to female artisans or artisan groups that are led by women.
This artist is currently supporting and providing for the education of their children, grandchildren, or children in their community, whether it be at the primary, secondary, or university level.
This artist uses traditional techniques handed down through the generations and/or creates culturally significant items, helping keep these traditions alive.
This artist positively impacts their community through job creation and provides jobs for 2 or more people.
This artist striving to supporting their own or their family's basic needs and improve their livelihood.
Every purchase from this artist has a profound impact on their livelihood and income.
This artist has dramatically improved their livelihood by working with NOVICA.
This artist supports children under the age of 18.
Adriana Trejo
Handcrafted seed bead jewelry
Cause Badges
Adriana Trejo Handcrafted seed bead jewelry
"I craft jewelry with tiny colorful seed beads we call 'chaquira.' I learned from my parents and they were taught by their grandparents; this family art has been handed down for generations."
"One of the things for which I am very grateful to NOVICA is that it allows me to give employment to members of my family and to continue promoting the support and growth of each one. This is vitally important to me. That, and having time with my daughters.
"We have made our NOVICA sales grow, and it now represents 50% of my income; I am very happy about that. It has given the opportunity for my daughter to study. And it also gives my husband time and resources to support our family.
"At first I must admit that it was difficult for me to adapt to the quality requirements of each piece, but when you understand that it is a piece that will cross countries; your perception changes. It's exciting. Know that someone uses a necklace or creation that you made with love and dedication.
"As I have grown, I have allowed myself to focus on my priorities. I would not have been able to achieve this without the girls working in the NOVICA office. They have given a lot of support and guidance in how to make modern and beautiful pieces.
"What I like most about my work are the colors we combine; color is the basis of our jewelry pieces. Creating a traditional piece combined with modern touches is great.
"I would like our customers to know that each piece is made with a part of us. That a part of my family goes in every piece we make. That our Huichol tradition is behind each one, as well as a piece of our history."
Original Artisan Story
"I craft jewelry with tiny, colorful seed beads we call chaquira. I learned from my parents and they were taught by their grandparents, as this family art has been handed down for generations. My grandfather also worked with amate paper, derived from the bark of wild fig trees. Our Aztec ancestors wrote pictographic books on amate paper.
"After we finished our chores around the house, we'd work on our crafts. I was only seventeen when my mother taught me, and I learned little by little.
"My first design was a ring, and I continued with a belt and other accessories. When I was nineteen, we moved to a large city and I began to work with my brother until I found a way to set up a workshop and craft my own designs.
"My two daughters are my motivation in life. Aleida was born in 2009 and Sofia in 2015. I'm beginning to teach this tradition to Aleida. Once she made a ring from beads and it was lovely, even more because it was made by her own little hands. She offered it for sale and it sold quickly. I told her, "Look! You were able to sell something you made yourself," and that motivated her a lot.
"What I like best about my work is letting my imagination fly. Playing with the colors and shapes inspires me. Every time I work on a new design, I try to imagine how it will look, and this is how I combine shapes and colors until I can see it finished. This is greatly motivates me.
"I remember a design that I found very difficult. It was a complex necklace with many colors and shapes. I used different shades of blue, red, orange, yellow and green, and figures like diamonds. It was large and dramatic. I began to think that maybe I wouldn't be able to make it after all, but I took my time. After three days of work, I finally finished this design. And I realized that you can do anything as long as you are dedicated and constant.
"Attention to detail is extremely important to me. It's essential to knot the threads neatly so that every piece is pretty. I so enjoy working with my family. But this work has also let me give jobs to others in my community."


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The King of Saudi Arabia has ordered the extension of the free Iqama for three months.Saudi King Salman bin Abdul aziz Al Saud has ordered a three-month extension of the free Iqama (residence permit) for expatriates.
The Saudi Press Agency quoted the Interior Ministry as saying on Sunday.
It is known that the validity of the visa will be extended for three months at no cost to the tourists whose visa have expired during the ban on entry and exit to Saudi Arabia.
In addition to the final exit visa, exit and re-entry visa were issued for expatriates residing in the state, but they could not use it during the lockdown, they will also get free three-month iqama facility.
Those expatriates who went out of the state with exit and re-entry visa but could not return on time due to lockdown will also get this iqama facility on the instructions of the King of Saudi Arabia.
According to the Saudi Interior Ministry, King Salman has ordered free Iqama benefits as part of the government's ongoing process to mitigate trade and economic losses in the coronavirus crisis.
News Room, july 05,2020


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What does swearing mean?
Definitions for swearing
Here are all the possible meanings and translations of the word swearing.
Princeton's WordNet
curse, curse word, expletive, oath, swearing, swearword, cuss(noun)
profane or obscene expression usually of surprise or anger
"expletives were deleted"
oath, swearing(noun)
a commitment to tell the truth (especially in a court of law); to lie under oath is to become subject to prosecution for perjury
Webster Dictionary
of Swear
a. & n. from Swear, v
Dictionary of Nautical Terms
A vulgar and most irrational vice, which happily is fast going out. Habitual swearing was usually typical of a bad officer. It may have originated in the custom too often demanded by law, of solemn asseverations on frivolous subjects.
Anagrams for swearing »
Chaldean Numerology
The numerical value of swearing in Chaldean Numerology is: 8
Pythagorean Numerology
The numerical value of swearing in Pythagorean Numerology is: 6
Examples of swearing in a Sentence
We then discovered that she had a bit of a foul mouth and kept swearing, much to our amusement.
It may be controversial but only if you simply extract the swearing and drugs and stuff from the context, it could well be that it's not so controversial.
I do the very best I know howthe very best I can; and I mean to keep doing so until the end. If the end brings me out all right, what is said against me wont amount to anything. If the end brings me out wrong, ten angels swearing I was right would make no difference.
The foolish and wicked practice of profane cursing and swearing is a vice so mean and low that every person of sense and character detests and despises it.
Don't trust a swearing man and a weeping woman.
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Translations for swearing
From our Multilingual Translation Dictionary
Get even more translations for swearing »
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Host a Parks for Pollinators BioBlitz this September to educate your community about pollinators, gain knowledge about local pollinator species and be entered to win a $1,000 prize or one of three prize packs.
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* The person registered for this product will be the person logged in. If you wish to purchase this product for someone other than the individual who is logged in, then please call customer service at 1-800-626-6772.
* We are currently working away from our office due to the ongoing pandemic. Certificate re-prints will be sent out when we return to our office. Unfortunately, at this time, we do not have an estimate of when that will be.
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The CPSI Prep Course Bundle includes the CPSI Preparation Course and the CPSI Practice Exam which will help prepare an individual to take the Certified Playground Safety Inspector Examination.
The CPSI Preparation Course includes 8 online modules which will help prepare an individual to take the Certified Playground Safety Inspector Examination. The course provides rich, in-depth analysis of ASTM standards related to playground safety focused on the process of safety inspection from design, through audit and inspection, to maintenance and risk management practices. The course also provides learners with scenarios to apply their understanding of this material.
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Once registered, you will have access to the course for 180 days. The course is worth 1.2 CEU upon completion of all course components.
Recommended study materials to accompany this course are the Consumer
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- Equipment for machines based on the MTZ chassis
- Wheel loader AMKODOR 134
- Wheel loader AMKODOR 134-01
- Backhoe loader AMKODOR 702ЕА
- Backhoe loader AMKODOR 702EA-01
- Backhoe loader AMKODOR 702EM-03
- Backhoe loader AMKODOR 703M
- Excavator-bulldozer AMKODOR 702EB with non-turning moldboard
- Excavator-bulldozer AMKODOR 702EB-02 with turning moldboard
- Excavator-bulldozer AMKODOR 702EBM
- Excavator-bulldozer AMKODOR 702EBM-01
- Road milling cutter for patching AMKODOR 8047A
- Road milling cutter for patching AMKODOR 8048M
Ведущее предприятие по производству дорожно-строительной, коммунальной, снегоуборочной, аэродромной, сельскохозяйственной и другой специальной техники и оборудования.
Пн-Пт 7.30-16.00
Milling drum AMKODOR АТФ-10
Milling drum ATF-10 is designed for milling a peat deposit with a milling method of peat extraction. The drum should be operated on peat fields prepared in accordance with the current "Regulations of technical exploitation of peat industry enterprises".
The working part of the drum is 6 mills with conical pins. The lifting of the working element to the transport position is carried out by the hydraulic system. The drum is equipped with an electric control system for stopping the mills. During normal operation of the milling cutter, no actuations occur. If, during the milling operation, jamming occurs due to stumps, driftwood or other objects, the milling cutter will stop and the sensor will operate with a shutter speed of 2 sec. in the form of sound and light signal on the panel located in the cabin. The jamming alarm of the milling cutters is triggered on any of the three installed sensors, depending on where the jam occurred.
Manual (RUS) download