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I am very happy to welcome my Guest Blogger, Sarah Hardie, talking about her love for her native New Zealand and her pride in her heritage. But is she a New Zealander!
New Zealand is a strange and wonderful place where the hills are alive with nature and sheep, where the beaches are rocky, beautiful and plentiful, and where there is technically no such thing as a New Zealander.
My Dad always says to me, "Do you realize that New Zealand is the only country in the world where we can't call ourselves New Zealanders?"
And it's true. When we fill out forms, we have to tick the box that says "New Zealand European/Pakeha". Firstly, I have never been to Europe, and nor has my family. My ancestors were born in Scotland and England, and only ever went to Europe to fight in the wars.
Secondly, "Pakeha" is a Maori word, which means "white ghost", a name given to our ancestors when they arrived on the shores of New Zealand in ships flying white sails 200 years ago. Some say it means, "White pig", or at least that's what the Maori kids at school used to tell us. Is it right for us to be officially labelled by a Maori word? By a word that is not our own?
Of all things, the New Zealand All Blacks winning the Rugby World Cup last year has bought this anomaly to the forefront of my mind.
The eyes of the world were on our tiny country for those four weeks of utter mayhem and national pride, with 20 countries competing for the Webb Ellis Cup.
On my dad's side of the family, I am a third-generation "New Zealander" and on my mum's side, I am fourth generation. My parents, all of my grandparents, and a couple of my great-grandparents were born in New Zealand, yet neither they nor I are able to call ourselves simply "New Zealanders".
Although I have a certain amount of pride in my Scottish and English heritage, I am more proud of the fact that the people who shaped my country were the ones who were brave enough to leave their homeland forever to spend months on a boat, often losing loved ones to sickness on the way to a land they had never seen before – a land that was all trees and rocky shores, barren of life except for the small, scattered Maori villages.
Let me be a bit arrogant for a second. I think the reason why people have coined phrases such as "Kiwi ingenuity", "I'm not a hero, I just did what any kiwi would do", and "She'll be right mate", and why people like former All Black Colin Meads who played a game of rugby with a broken arm are our national heroes is because we were the ones who decided to take a risk, a huge risk, a risk that is not even available to take these days. We were the ones who decided not to stay at home where it was familiar and safe. We decided to get on that boat and start a new country. That's pretty brave in my opinion.
During the Rugby World Cup, my dad, sister and I donned blue and white face paint and headed to the stadium to support Scotland, one of the countries we are proud to say our ancestors come from.
There is nothing wrong with being proud of your heritage and supporting other teams for a bit of fun, but where do we draw the line at being defined by our heritage?
I love the sound of the bagpipes, and jumping around yelling at Scotland to "run the damn ball!" and cheering when they score, but when I stood up and sang Flower of Scotland (the national anthem), the hairs on the back of my neck stayed flat and my heart beat was normal.
Yet when I stood up with my sister in my living room on September 9 when the All Blacks kicked off the RWC with a match against Tonga, put hand on heart, and sang God Defend New Zealand, tears of pride came to our eyes.
When the All Blacks performed the Haka, the hairs on the back of my neck stood up. When they kicked off, my heartbeat was faster than normal for the next 80 minutes.
Every Anzac Day, when I attend the dawn service in Wellington with my family, I think of the New Zealanders who fought and died for our freedom regardless of the colour of their skin nearly 100 years ago. At least on that one day, we all get to at least feel like New Zealanders, no matter where our ancestors came from.
How many generations of people born and raised in New Zealand will it take to shake off the words "Pakeha" and "European" and when will we get to tick the box that says "New Zealander"?
You May Say I'm a Dreamer Blog: http://youmaysayimadreamer-sh.blogspot.co.nz/
Twitter: https://twitter.com/#!/sarahcornflake
Pinterest: http://pinterest.com/cornflake1/
Flickr: http://www.flickr.com/photos/sarahhardie/
Sarah lives in Wellington, New Zealand and works in the media industry. She is a writer working on her first novel which is based in her city, and a non-fiction project on a rural New Zealand town's dedication to keeping the Anzac tradition alive. She is also a very proud New Zealander who loves her sweet as life and enjoys flinging off her jandals on the beach to go for a swim in the sea wearing her togs in the arvo followed by a good steak on the barbie at the bach. Choice bro.


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The facts are indisputable. Disability is steadily rising in the American workforce. This reduces worker productivity and damages your business. It also threatens the financial lives and future security of your employees and their families.
What can you do? Like you, many employers are looking for ways to help their employees deal with this threat. Many are introducing wellness programs to help lessen the likelihood of a worker becoming disabled. Some employers are also giving employees the resources and information to help them prepare for the possibility, and deal with the financial hardship it can cause.
Remember: By helping your employees lead healthier lives and prepare for the unthinkable — a loss of income due to a disability — your organization benefits too.

subset: commoncrawl


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Tuesday, May 27, 2014
Luck in Chess
Heisman suggests that chess authors use luck to mean that there is no randomness in chess in the selection of moves. There are no dice or other random elements at play and it is only the choice and effort of the players which determines the moves made. He goes on to state that choosing moves is only one aspect of the game, and others may be affected by luck. He then goes on to talk about good move and games played by low rated players which could be considered lucky, and weak moves and games played by high rated players which may be considered unlucky. This use of luck in chess I strongly disagree with as it takes away a players responsibility for his actions and gives a person excuses to rationalise a bad loss or a good win. I take a much more down to earth view. If I play badly and lose to a lower rated player than me, then that isn't anything to do with luck, the best man won on the day. To avoid this happening in the future, I need to ask some hard questions about my play, and my preparation for the game. On the other hand, if I beat a player much higher rated than me, rather than saying I was lucky that they didn't play their best chess, I can turn around and rightly be proud of my achievement.
Another issue he talks about is luck of the draw in a tournament. Sometimes draws seem to be favourable to players, while sometimes they are really bad. However, again, this seems to me to be an excuse players make when results don't necessarily go with them. I remember playing in a weekend tournament in the UK and arriving for the first round where my opponent hadn't turned up. The rules were that players without a first round opponent could be re-paired up to 30 minutes after the start of the round. After 20 minutes I had no opponent to play and was thinking in terms of getting a full point bye when IM Chris Baker walked in the door and asked of it was to late to join the tournament. I was asked if it would be ok to play with Chris, I said yes, no problems, we played, I lost and turned a full point bye into a first round loss. As a player in the top half of the draw, it was also a first round point dropped. Now you could say I was unlucky in that instance, but I wouldn't say that. Those were the rules, and that was the draw. Simple as!
While I use a lot of ideas from a lot of coaches in my lessons (including Dan Heisman), I try to make my students take responsibility for their mistakes and their victories. I am working hard towards making a future generation of chess players accountable for their actions, and to take charge of improving their play. I now have kids coming up to me telling me about their blunders, about how they didn't work hard enough before a tournament or didn't get enough sleep due to parties so tired through the day, things which they intend to put right in the future. They are not making excuses, they are analysing their mistakes in playing and preparing for events which they can then attempt to remedy. I get immense satisfaction when kids have turned the corner from just wanting to win every game they play to realising that losing isn't a bad thing as long as things are taken from the game.
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I think that there is some luck in chess, if you think of "luck" as something with a low percentage of happening, or something that is unlikely to happen.ReplyDelete
For example
a novice player rated 800 might blunder every one out of 10 moves.
a 1600 rated player might blunder one out of every 40-60 moves.
A Master might blunder once out of every 1000 moves.
So if you are the one that happens to be playing against the master when he makes this "1 out of a 1000" blunder - you are possibly getting "lucky".
The master is not going to blunder like this often, but we are all human, and all make mistakes at some point. The stronger players just make mistakes less often.
It is like you have a 1 in a 1000 chance of something, and if you pick that one, most people would say that is "lucky".
I played a rated game against Life Master Brian Wall last summer. He missed a simple mate in one with a battery of Bishop and Queen pointing at h7. This is probably something that he is going to see 99,999 times out of of 100,000. But in this particular game he missed it. I am fine with saying "I got lucky", because these things do happen in a game.
Luck favors the prepared mind!
Hi Timothy, first congratulations on a good win, sounds like you stepped up in that game. When a lower rated player does step up (sorry, I'm assuming you are lower rated than the life master), it puts all sorts of pressures on higher rated players, and while it doesn't force the stronger player to blunder it increases the chances of that blunder happening.ReplyDelete
On the subject of 'chance', which you seem to be using synonymously with luck, I'd prefer to believe that it doesn't exist. There are statistical advantages to certain openings for example, but choosing an opening based on these isn't lucky, it's using data in an analytical way. The statistical model that you're using makes chess sound like some kind of slot machine where there will be payouts every percentage of times. However we know this isn't the case, and there are many factors which influence the result of a game, some of which have nothing to do with chess itself (eg work issues, bills, family issues which may play on the mind etc).
On the other hand, you might be suggesting that when a player is lucky that his strong opponent missed something obvious, then it is a case of 'being in the right place at the right time'. As a matter of fact, I'd completely agree with this, but I'd say that has nothing to do with luck but is a direct result of someone putting them self into that opportunistic position and taking advantage of it.
My biggest problem with using luck in chess is when it is used as an excuse for failure or success. You had a good win and beat a player. You were the better player on the day. Accept it and enjoy that accolade. You deserve it :)


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With Dr Kevin Cruickshank BVSc, BSc(Hons), a South African trained (Onderstepoort) and qualified vet living and practising in Australia
How to Afford the Best Care for Your Pet
If I told you the most you'll ever have to pay at the vet for an accident or illness is $100, would you think that's a good idea? Well that's exactly what Pet Insurance can do for you. As we approach the end of the financial year don't we all wish we could have a few more dollars left in our pocket? Big vet bills never come at a convenient time. Private health insurance for pets can absorb those costs and make your budgeting so much easier.
So what should you look for in a Pet Insurance Policy?
Many home and contents policies now have an optional extra for pet cover. Frequently it is restricted to accident only and does not cover sickness. A specialised Pet Insurer is far better. Key points to look for are:
If you don't already have it, I would really urge you to consider getting private health insurance for your pet. For a small monthly cost it can make a huge difference to their care and your peace of mind. If you consider that every 6 seconds a pet owner is faced with a vet bill of over $1000. Can you afford not to have you pet insured?
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29. Sign language with a maid
Once I had a Tamilian maid
My mother tongue is Marathi but I am born and brought up in Bengaluru. In addition to Marathi, I speak Kannada and Hindi.
Most of the maids available here are Kannadiga, Tamilian, and Telugu. Now, I have a Kannadiga maid. But once, I had a Tamilian maid who would speak in Tamil only.
I would explain what work I wanted to be done, with made-up sign language and action. She would understand my actions and also read my lips. Initially, it was very difficult, but we got adjusted to each other because she had very good grasping power.
I later discovered the reason. Her daughter could not speak due to an accident. Hence, they had learned to communicate in sign language.
She worked in four houses and would tell me stories of their houses. It was a good and hilarious time.
Author does not want to be named.


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Electrosurgical Devices Global Market – Forecast To 2023
Electrosurgery uses electrical energy to create thermal destruction of tissue through coagulation. Electrosurgical devices are the medical devices used for almost all types of surgeries such as cardiac, orthopaedic, cosmetic and dermatological, gynaecological, plastic surgery, ENT, maxillofacial, urological, neurological and general surgical procedures as well as certain dental procedures, etc. Electrosurgical units (ESU's) are used for surgical cutting or to manage blood loss by causing coagulation (homoeostasis) during surgery. The increasing acceptance of electrosurgical devices is mainly due to the advancements in electrosurgical devices that facilitate the reduction of earlier problems faced by traditional electrosurgical products such as collateral damage to tissues, eschar (dead tissues) formation and also limit sticking of tissues. The electrosurgical devices global market is expected to grow at single digit CAGR to reach $6,178.2 million by 2023.
The global electrosurgical devices market is divided into products, surgery and geography. The global electrosurgical devices products market is segmented into electrosurgical generators and monitors, instruments/units, plasma and smoke management systems and accessories. The electrosurgical instrument is further classified into monopolar and bipolar instruments. Monopolar instruments are further segmented into electrosurgical electrodes, electrosurgical pencils, suction coagulators and irrigation devices and monopolar forceps. Bipolar instruments are further segmented into vessel sealing instruments and electrosurgical bipolar forceps. Plasma based systems are further segmented into argon systems and helium systems. By surgery, the electrosurgical devices market is broadly segmented into cardiovascular, cosmetic &dermatological, gastrointestinal, general, gastrointestinal, gynaecological, neurosurgical, oncology, orthopaedic, urological, dental and others and geographically electrosurgical market is divided into North America, Europe, Asia-Pacific and Rest of the world.
Further the electrosurgical devices global market is separarted by geographical regions into North America, Europe, Asia-pacific and Rest of the World.
Learn how to effectively navigate the market research process to help guide your organization on the journey to success.Download eBook


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You Are Being Poisoned
Everyday we chow down on chemically produced foods that carry deadly poisons. Today when we eat meat, poultry and dairy, we eat the residue of everything the animal ate, including growth hormones, pesticides and contaminants.
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Following are some of the harmful chemicals commonly found in our food and personal products, along with descriptions of what they are, where they're found and why they're bad.
Like what you're reading? Then LIKE us on Facebook!
GMO Foods
Monsanto is an American multinational agricultural biotechnology corporation responsible for hazards such as Agent Orange. They are currently well known for Genetically Modified agriculture, owning nearly 90% of staple GMO crops such as corn, soy, and cotton. In independent studies GMO food has been linked to organ failure, and a recent Russian study has concluded near-total sterility in GMO-soy-fed hamsters by the third generation.
The question of whether or not genetically modified foods (GMO's) are safe for human consumption is an ongoing debate that does not seem to see any resolution except in the arena of public opinion. Due to lack of labeling, Americans are still left at a loss as to whether or not what is on the table is genetically modified. This lack of information makes the avoiding and tracking of GM foods, very difficult. The top 10 worst GMO foods for your "do not eat" GMO foods list include corn, sugar, aspartame, papayas, canola oil, cotton oil, dairy, zucchini, and yellow squash.
The best advice: steer clear of them altogether.
Food Additives
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When most of us think of harmful food additives we think of Monosodium Glutamate (MSG) which is still in many processed foods, but unfortunately MSG appears to be the least of the poisons now found in our food.
In 2008 Melamine was found in infant formula and some food products from China; the FDA went on record to say it was OK, despite sickening tens of thousands. Dangerous food additives appear in nearly all processed foods with even the most common food dyes Red 40, Yellow 5 and Yellow 6 being linked to cancer.
Most recently 92,000 pounds of frozen chicken was recalled because it contained "blue plastic pieces," while McDonald's Chicken McNuggets have been found to have "silly putty" chemicals in them. In fact, some researchers estimate that today's chicken is so full of chemicals that it only contains 51% actual meat.
Not all fluoride is bad; only the type promoted by dentistry and added to our water and food supply.
Calcium fluoride is a naturally occurring mineral, while its synthetic counterpart, sodium fluoride (silicofluoride), is an industrial-grade hazardous waste material made during the production of fertilizer. Its past history includes patented use as rat poison and insecticide.
There are many blind- and double-blind studies that show sodium fluoride has a cumulative effect on the human body leading to allergies, gastrointestinal disorders, bone weakening, cancer, and neurological problems. In this case, the EPA's Union of scientists issued a white paper condemning fluoridation of drinking water.
However, as a hazardous waste, it is extremely expensive to dispose of as such. And here might be a clue as to why this chemical, more toxic than lead and almost on par with arsenic, has been disposed of for our consumption.
A dangerous heavy metal in its natural quicksilver form, but more so as the neurotoxin, methylmercury, released into the environment by human activity.
In both organic and inorganic form, mercury wreaks havoc with the nervous system — especially the developing nervous system of a fetus. It penetrates all living cells of the human body, and has been documented most as increasing the risk for autism.
This calls into question mercury's use in dental fillings, vaccines, and just about anything containing high fructose corn syrup — a near staple in the American diet . . . including baby food. But the Corn Refiners Association naturally supports this chemical that is "dangerous at any level."
Do you use a little Equal (also known as aspartame) to sweeten your drinks?
Aspartame, the king of artificial sweeteners, was allowed to the market in 1981 when the U.S. Commissioner of Food and Drugs, Arthur Hull Hayes, overruled FDA panel suggestions, as well as consumer concerns.
Aspartame is a neurotoxin that interacts with natural organisms, as well as synthetic medications, producing a wide range of proven disorders and syndromes. It is now nearly everywhere, moving beyond sugarless products and into general foods, beverages, pharmaceuticals, and even products for children. It recently has been renamed to the more pleasant sounding AminoSweet.
Personal care and cleaning products
Everyday household items and cosmetic products are applied directly to the skin, absorbed through the scalp, and inhaled. The list of common products and their chemical components is encyclopedic. The sum total of the overwhelming presence of these chemicals has been linked to nearly every allergy, chronic affliction, and disease known to man. Most recently, household cleaning products have been linked to breast cancer and ADHD in children.


text: Cutting back on light exposure time and turning up light intensity, and cutting out fertilization (and carbon addition) seems to have helped. May take a few months for plants to recover. We'll see. Sort of the typical first planted tank cycle? Update #1: yes, that's a photo of my algae, but it's the good kind. Not posting photos of the bad stuff.


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How To Get To Heaven
A teacher asked the children in her Sunday School class, "If I sold my house and my car, had a big garage sale and gave all my money to the church, would I get into heaven?" "NO!" the children all answered. "If I cleaned the church every day, mowed the yard, and kept everything neat and tidy, would I get into heaven?" Again, the answer was "NO!" "Well," she continued, "then how can I get to heaven?" In the back of the room, a five-year-old boy shouted out, "You gotta be dead!"
A Very Faithful Woman
An elderly lady was well-known for her faith and for her boldness in talking about it. She would stand on her front porch and shout "PRAISE THE LORD!" Next door to her lived an atheist who would get so angry at her proclamations he would shout, "There ain't no Lord!!" Hard times set in on the elderly lady, and she prayed for GOD to send her some assistance. She stood on her porch and shouted "PRAISE THE LORD. GOD I NEED FOOD!! I AM HAVING A HARD TIME. PLEASE LORD, SEND ME SOME GROCERIES!!" The next morning the lady went out on her porch and noted a large bag of groceries and shouted, "PRAISE THE LORD." The neighbor jumped from behind a bush and said, "Aha! I told you there was no Lord. I bought those groceries, God didn't." The lady started jumping up and down and clapping her hands and said, "PRAISE THE LORD. He not only sent me groceries, but He made the devil pay for them. Praise the Lord!"
Out of Luck
A guy named Joe finds himself in dire trouble. His business has gone bust and he's in serious financial trouble. He's so desperate that he decides to ask God for help. He begins to pray… "God, please help me. I've lost my business and if I don't get some money, I'm going to lose my house as well. Please let me win the lotto."
Lotto night comes and somebody else wins it. Joe again prays… "God, please let me win the lotto! I've lost my business, my house and I'm going to lose my car as well". Lotto night comes and Joe still has no luck. Once again, he prays… "My God, why have you forsaken me?? I've lost my business, my house, and my car. My wife and children are starving. I don't often ask you for help and I have always been a good servant to you. PLEASE just let me win the lotto this one time so I can get my life back in order." Suddenly there is a blinding flash of light as the heavens open and Joe is confronted by the voice of God Himself: "Joe, meet Me halfway on this. Buy a ticket."
Wrong E-mail
A Minnesota couple decided to vacation to Florida during the winter. They planned to stay at the very same hotel where they spent their honeymoon 20 years earlier. Because of hectic schedules, it was difficult to coordinate their travel schedules. So, the husband left Minnesota and flew to Florida on Thursday. His wife would fly down the following day.
The husband checked into the hotel. There was a computer in his room, so he decided to send an e-mail to his wife. However, he accidentally left out one letter in her e-mail address, and without realizing his error, he sent the e-mail.
Meanwhile…..somewhere in Houston, a widow had just returned home from her husband's funeral. He was a minister of many years who was called home to glory following a sudden heart attack. The widow decided to check her e-mail, expecting messages from relatives and friends. After reading the first message, she fainted.
The widow's son rushed into the room, found his mother on the floor, and saw the computer screen which read:
To: My Loving Wife
Subject: I've Arrived
Date: 16 May 2003
I know you're surprised to hear from me. They have computers here now and you are allowed to send e-mails to your loved ones. I've just arrived and have been checked in. I see that everything has been prepared for your arrival tomorrow. Looking forward to seeing you then! Hope your journey is not as uneventful as mine was.
P.S. Sure is hot down here!
A Special Hymn
A preacher was completing a temperance sermon; with great expression he said, "If I had all the beer in the world, I'd take it and throw it into the river."
With even greater emphasis he said, "And if I had all the wine in the world, I'd take it and throw it into the river."
And then finally, he said, "And if I had all the whiskey in the world, I'd take it and throw it into the river."
He sat down.
The song leader then stood very cautiously and announced with a smile, "For our closing song, let us sing Hymn # 365: "Shall We Gather at the River."
The Frozen Bird
A little bird was flying south for the Winter. It was so cold the bird froze and fell to the ground into a large field.
While he was lying there, a cow came by and dropped some dung on him.
As the frozen bird lay there in the pile of cow dung, he began to realize how warm he was.
The dung was actually thawing him out!
He lay there all warm and happy, and soon began to sing for joy.
A passing cat heard the bird singing and came to investigate. Following the sound, the cat discovered the bird under the pile of cow dung, and promptly dug him out and ate him.
Morals of the story:
(1) Not everyone who puts dung on you is your enemy.
(2) Not everyone who gets you out of the dung is your friend.
(3) And when you're in deep dung, it's best to keep mum!
Ever Wonder…
Why the sun lightens our hair, but darkens our skin?
Why don't you ever see the headline 'Psychic Wins Lottery'?
Why is 'abbreviated' such a long word?
Why is it that doctors call what they do 'practice'?
Why is lemon juice made with artificial flavor, and dish washing liquid made with real lemons?
Why is the man who invests all your money called a broker?
Why is the time of day with the slowest traffic called rush hour?
Why isn't there mouse-flavored cat food?
Why didn't Noah swat those two mosquitoes?
Why do they sterilize the needle for lethal injections?
You know that indestructible black box that is used on airplanes? Why don't they make the whole plane out of that stuff?!
Why are they called apartments when they are all stuck together?
If con is the opposite of pro, is Congress the opposite of progress?
If flying is so safe, why do they call the airport the terminal?


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As reported by BBT, by 2020, half of the global workforce will be made up of millennials. And we are repeatedly told that millennials – the generation born approximately between 1980 and 2000 – have distinctive tastes, seek out unique experiences, are socially minded, tech savvy and constantly switched on. But in 2019, does this ring true?
What exactly do these 20 and 30-somethings expect and need from their travel experiences – and, more crucially, how are they changing the shape of the travel business? Millennials have grown up in a world of laptops, the internet and smartphones and are the first generation of true digital natives.
Consequently, they tend to depend on technology for the entire travel booking process, from reading website reviews to mobile booking. However, research for American Express Global Business Travel's Traveller 360º report, which was published last year and surveyed 2,000 UK business travelers, found three-quarters of them used an online system or app to book business travel, with nearly six-in-ten describing it as easy to use.


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There are three signs of senility. The first sign is that a man forgets his theorems. The second sign is that he forgets to zip up. The third sign is that he forgets to zip down.
- Paul Erdos
Death and sex are the dominant reality of our day.
- Peter Porter
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It CAN be done!
Posted by SmartActors | Leave a comment
It CAN be done!
Photo courtesy of graphics16.com
At SmartActors.com we'll show you how! Sometimes all we need is a little guidance and some serious STRAIGHT-UP in your face info and at SmartActors.co that's ALL we have to offer! So, don't lose HOPE nor FAITH because you NEED both to get through all those ICKY rough patches, but we promise you, it CAN be done! So don't wait any longer!
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Photo courtesy of dereila.com
So, we are waiting on YOU…. WHAT are YOU waiting on!
SMARTACTORS.COM…. It's where ALL the SMART Actors go!


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Cricket Weaving Loom Kit: 10 inch
Compact and capable, the Cricket Rigid Heddle Loom from Schacht Spindle Co. has a 10 inch weaving width, giving plenty of room to make a variety of projects without sacrificing portability. This wooden loom comes with everything you need to weave-two stick shuttles, a warping peg, threading hook, two table clamps and an 8-dent rigid heddle reed. Also includes two balls of Wool-Ease yarn in #099 Fisherman for FREE! This item comes with a one year warranty and replacement parts are available through the manufacturer. Assembly required. Dimensions: 11 inches wide x 18 inches long x 6 inches highWeight: Approx. 4 lbs Rigid Heddle Loom patterns may be used in conjunction with this loom. FREE Weaving Patterns on LionBrand.com: Woven Pixelated Scarf The Boyfriend Scarf Woven His and Hers Scarves With One Warp Note: We carry the updated model of this loom, redesigned with the ratchet gear and dog on the outside of the loom.


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Creative Biolabs provides highly specific and sensitive pan anti-propionyllysine antibodies and site-specific anti-propionylated protein antibodies based on our excellent High-Affi™ technology. These antibodies are produced by immunizing mice with propionylated BSA or KLH or with a synthetic propionyl peptide and purified by affinity chromatography. They do not cross-react with acetylated and other acylated peptides.
Propionylation has been identified as a novel type of protein post-translational modification on lysine. Lysine propionylation is structurally similar to lysine acetylation, has been well demonstrated in both prokaryotes and eukaryotes. The reversible lysine propionylation has been found in histones with different modified sites, such as lys12, lys14, lys18, lys23 of H3 and lys12, lys16 of H4. Besides histones, propionylation was also found in non-histones such as p53 and regulatory enzymes p300/CBP. The two previously known acetyltransferases, CREB-binding protein and p300, could catalyze lysine propionylation in histones. The two enzymes can carry out autopropionylation in vitro in a fashion similar to autoacetylation. Propionylation of lysine is dynamically regulated as histone deacetylase sirtuin 2 (Sir 2) can remove this modification in the presence of NAD+. These results suggest that histone propionylation might share the same set of enzymes with histone acetylation.
Like acetyl-CoA, propionyl-CoA is an important intermediate in biosynthesis and energy production. Propionyl-CoA versus acetyl-CoA may determine the difference of modifications. Human histone H4 and bacterial propionyl-CoA synthetase are propionylated at specific lysine residues that have been known previously to be acetylated. Histone propionylation may provide a novel epigenetic regulatory mark for cell metabolism. Generally, given the unique roles of propionyl-CoA in energy metabolism and the significant structural changes induced by the modifications, propionylation are likely to have important but distinct functions in the regulation of biological processes. It includes:
The identification of lysine propionylation described here provides an entry point for future functional studies in cellular physiology and pathology.
Fig. 1. A. Structures of three short-chain CoAs, the acetyl-CoA, propionyl-CoA, and butyryl-CoA, as well as the three modified lysines, acetyllysine, propionyllysine, and butyryllysine. B. An illustration of novel lysine propionylation and butyrylation sites in histone H4. Ac, acetyl; Me, methyl; Buty, butyryl; Prop, propionyl. (Chen Y. et al. 2007)
However, other proteins subject to this modification remain to be identified, and the enzymes processing this modification need to be characterized. Antibodies are the most powerful tools in PTM discovery and identification, and they also benefit for studying the functions. Creative Biolabs has years of experience in antibody discovery and production services. We can tailor your need and provide the most highly specific and high-quality antibody products.
Creative Biolabs can provide a comprehensive list of PTM-specific antibody production services of your choice.


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Dealing with Rejection – Part III
For context, read
Dealing with Rejection – Part I
and Dealing with Rejection – Part II.
In sports you can have a lucky bounce, lucky call or a lucky shot. There are lucky horseshoes, lucky clovers, and lucky rabbit's feet. You can find lucky pennies, eat lucky charms, and just plain feel lucky. For as long as I can remember, I've heard people use the term "getting lucky" almost exclusively in regards to sex.
To me, though, getting lucky has always been about dating and romance and rarely about sex. Finding that girl that I simply click with when I least expect it is getting lucky. Asking someone out who is so clearly out of my league and having her accept is getting lucky. Even randomly meeting a wonderful girl in some chance encounter and not having it lead anywhere is still getting lucky.
Despite every wonderful thing that's happened to me over the course of my life, I have never gotten luckier than finding myself a high school freshman wandering Harvard Square with a lovely college girl.
I'm not sure how it worked out that my parents gave me the freedom of the city at 14, but I had somehow secured their trust. The school provided students MBTA passes, so we had free reign of the busses and trolleys. My parents had given me a pager that we got cheap from a deal on the back of a Mountain Dew box. If they wondered where I was or why I was late, they'd page me and I'd call them from the nearest pay phone. I felt it was a sweet deal. And because they trusted me I don't remember ever lying to them about what I was up to or where I was.
Except once.
I told my parents I was catching a movie with my friend Morgan, a classmate of mine and the closest thing BUA had to a rebel or bad girl. The two of us often spent time hanging out downtown or in Cambridge, since she lived in Somerville.
Morgan had an older boyfriend her parents didn't approve of and would occasionally have me cover for her. I didn't approve of him either. He was creepy and she was creepy when he was around, but after two years at an all-boys boarding school, I wasn't exactly rolling in female friends. For the first time, Morgan was covering for me.
I stashed my bag at Vincent's house, changed clothes to something nicer, and booked it over to the GSU where I met the red headed Virginian for an evening on the town.
Her name was Nikki. She had two brothers and a sister, all older and all back in her small town in Virginia. She had three dogs, her favorite a very sweet Dalmatian named Daisy whom she swore was retarded. She was open option and couldn't decide between studying biology to become pre-med, communications, or education.
All those facts have stuck with me over the years, but the most important fact to me was that she thought I was funny. I'm sure my humor was immature, but apparently it was up her alley.
We grabbed the T across to Harvard Square and shopped for a little. We ate pizza at the little parlor tucked above the entry to the Garage. Nikki rolled her eyes when I took her into a comic book store for a few minutes, but even she could appreciate the sculpting of the figures and the artwork on the walls. She even professed a secret love of MTV's Liquid Television and some of the stranger animation out there. It felt like heaven.
Image by Rose Lincoln.
We went to Harrell's Ice Cream, and shared a cup (I don't even like ice cream and she said she wasn't hungry enough for her own). I told her about some of the history of the city, spouted a few random facts, and tried to teach her how to do a Boston accent. She told me about her family, explained the lymphatic system, which she was studying at the time, and tried to teach me to speak with a drawl.
Soon, the sun was down and it was getting chilly. We cinched our coats tightly and slowly meandered through Harvard Yard, watching the people flit every which way, a pick-up game of touch football happening in the midst of one of the open fields.
I felt Nikki's hand slip into mine and had to concentrate to keep from shaking. I had never even been on a date with a girl my own age, let alone a gorgeous college girl who was clearly way out of my league. This was utterly clear to me in the moment. If she noticed me shaking, she didn't say anything.
"So what are you studying? Have you picked a major?" she asked.
"Um, a little bit of everything right now. I've got time before I need to choose a degree," I told her. It was as honest an answer as I could give without giving my age away. "I'm taking physics right now and a math class that's as much about the history of math as it is about the math itself."
"That sounds cool."
"Yeah, it's pretty neat." I felt the telltale buzz in my pocket. "Excuse me," I said, separating our hands and digging into my pocket for the pager.
"Is that a pager?"
"Yeah," I acknowledged glancing at the screen. It was my parents. "I gotta find a pay phone and give a call. It's my parents."
"Ok," she said.
We headed back to Harvard Square proper and found a payphone. I pulled out the little tape recorder Vincent had loaned me. Nikki looked quizzically as I played the coin tones into the phone. I held my index finger up to my mouth and shushed her with a smile.
"Hello," came my mom's voice.
"Hi mom. You beeped me?"
"Hi Ben. Just wondering when you'll be home. I was just about to start cooking dinner."
"I've already eaten, but thanks for asking," I said.
"What time is the movie?" I had completely forgotten to check listings and times.
"Um, the movie is already over. We're just hanging out now."
"What?" I heard Nikki say in the background.
"Oh. Well tell Morgan I say hi."
"Will do, mom. Talk to you later." I clicked the phone back into place as quickly as I could and turned back to Nikki. "Sorry about that. Wanna keep walking?"
"What movie?"
"No movie. Do you want to wander over by the Charles?" It was obvious that changing the subject was not covering my mistake.
"You told your mom the movie was over. What movie?"
I sighed. I didn't like lying and the only thing to do was come clean. "I kind of told my mom I was catching a movie with a friend so she wouldn't worry about where I was."
"Your parents still keep track of you?" she scoffed. "That's kind of lame." I'm pretty sure I turned beet red with that deer in headlights look. Nikki's eyes narrowed and she looked hard at me. "How old are you?"
I was done lying and avoiding the topic. "I'm 15," I admitted.
She began to laugh. "Oh my god," she said, her head lolling back. "So did you skip a few grades?"
"I'm a freshman." I swallowed hard. "In high school."
Her jaw dropped. I didn't know what to say. I felt a chasm of silence despite cacophony of Harvard Square overriding everything.
She finally smiled angrily at me and snapped, "Have a nice night." Before I had a chance to respond, she had turned and disappeared into the crowd.
To Be Concluded in
Dealing with Rejection – Part IV
« Dealing with Rejection – Part II
Dealing with Rejection – Part IV »


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Ok, so it's a pie chart, but whatever. I like it. From scifiwire.com
Ok, so it's a pie chart, but whatever. I like it. From scifiwire.com
It's been a while since I had a chance to post anything. Excuses, excuses, I hate when I hear myself start to make them. I've had this issue of Nylon sitting around my house for a while. It's the February '09 issue with Camilla Belle on the cover (star of the incredibly shit remake of "When A Stranger Calls". I thought it was shit, but I know it's REALLY shit when my wife makes an effort to stay awake just to see how bad it can get).
But Nylon magazine, I don't know if it's just because I haven't had time to read recently, but goddamn, picking up this magazine from the pile I have in the home office* this evening really reminded me how fun designing and shooting a cool ass fucking magazine can be. I went through this issue from beginning to end and while I'm happy to admit I didn't read any of it, it felt so nice to turn through a magazine that felt like it was fun to put together. The photography reminds me of my friend who never speaks to me called Tracy Goudie, an excellent photographer… one of those rare photographers like Joel Salcido, who you know you can leave alone with any project and they will deliver way more than you expected… (assuming they still take your calls). Here's a bunch of stuff from the magazine. I don't have a lot to say about the design, just look at it and … well whatever. Sorry about the bad photos. (more…)
Read this post on Michael Fleming's alphabetical Star Wars illustrations on io9 tonight, thought they were very cool. Would love to get him to illustrate something for me in the next issue of GivingCity, and have the perfect story for him to do that on, but I imagine he's out of my budget's reach right now. Perfect for what I'm looking for. May have to email him and do some extreme email ass-kissing. Take a look at his work here.
He also has a Lost/Trek crossover set here. Here is his site.


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Hey, TV dads can be kind of like real dads, right?
Louie C.K. took home an Emmy for best comedy writing for his FX show "Louie" tonight, with other big names like "Two and a Half Men" star Jon Cryer winning this year's best comedy actor award and "Breaking Bad" actor Aaron Paul winning for best supporting actor in a drama.


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A corporation or LLC is the best alternative for an artist. However, because there are costs involved in beginning a corporation/LLC, most artists do not incorporate until they begin making real money. A corporation is a company which is owned by stockholders (i.e., band members) and an LLC its members. A corporation/LLC is preferred because it provides two advantage that a sole proprietorship and partnership do not: (1) limited liability, and (2) tax benefits. Under the concept of limited liability, if the artist does something and gets sued, the plaintiff is limited to recovering from the corporation/LLC only, not from the artist or band members individually. Hence, under a corporate/LLC shield the artist cannot have his or her home taken away or wages garnished. An accountant or tax attorney should be contacted concerning the tax advantages. If an artist decides to incorporate, they will usually form what is known as a "loan-out" corporation. Under this concept, the corporation/LLC contracts with other parties for the artist's services. For example, if the artist gets a record deal, the corporation/LLC would sign the contract and would provide (i.e., loan-out) the services of the band.
It would be helpful for the artist to engage a professional to help select and properly set-up the above business forms.
Ben McLane Esq
Monday, May 31, 2010
Music Business/Law Tips - "Business Formation" (Part 2)
Posted by Ben McLane, Music Attorney at 10:31 AM
Subscribe to: Post Comments (Atom)


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2009-06-13 I was thinking of updating my profile pic. Full body shots are rarely useful for it, but I'd gotten the lighting just-so on this one, so I thought I'd share it. Call it a vanity pic. Unretouched, of course.
Added it to my flickr stream too: http://www.flickr.com/photos/quiteoh/
This shot was taken in Midian City slurl.com/secondlife/Midian%20City/138/174/29


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http://www.agricareers.ie/wp-content/uploads/2019/01/logoo-1-300x67.png 0 0 admin http://www.agricareers.ie/wp-content/uploads/2019/01/logoo-1-300x67.png admin2017-03-24 11:37:512017-03-24 11:38:21Loughlinstown Training Centre
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Website: www.dublintrainingcentres.ie


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Virtual sports have been attracting the attention of many igaming executives over the past month or so as operators look to counteract the widespre
The Governor of Puerto Rico Rosselló Nevares has announced plans to introduce legislation to regulate online and in-person sports betting in the US-controlled territory.
A bill from New Jersey Assemblymember Ralph Caputo would formalise the penalties imposed on licensees that offer odds on sporting events for which betting is prohibited, with the guilty parties facing fines and automatic licence suspensions.
The Department of Justice (DoJ) is set to extend the window in which it will not enforce its revised interpretation of the Wire Act, according to sources close to the matter.
The Department of Justice's decision to revise its interpretation of the Wire Act could have a major impact on the nascent US iGaming industry. Or, as some suggest, its impact could be felt in gaming verticals that are well-established and generating money for operators and states alike. A selection of speakers from ICE Sports Betting USA discuss the DoJ's about-turn.
Virtual games specialist Kiron Interactive has struck a deal with Sportech Racing and Digital, a division of pools and sports betting operator Sportech, to supply virtual racing to racetracks across Latin America.


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Sea Symphony
Review of the Vaughan Williams concert, March 2016
Performances of Vaughan Williams's music continue to come to our attention from all around the world.
I had the immense pleasure of hearing A Sea Symphony in Exeter Cathedral in March, preceded by Mendelssohn's Overture Calm Sea and Prosperous Voyage and a new work by Andrew Millington, The Seafarer, which included a quotation from the symphony. Andrew then conducted the Exeter Philharmonic Choir and The Sinfonietta in a marvellous performance of the Vaughan Williams, with two outstanding soloists in Catherine Hamilton and Julian Rippon. Having had to miss John Wilson's Royal Festival Hall concert in January, I was particularly glad to be invited to Exeter for a concert which will live long in the memory. All concerned were on top form, with the choir enunciating Whitman's poetry with beautiful clarity, and the orchestra fully engaged with this varied and demanding score.
Simon Coombs, Chairman, Ralph Vaughan Williams Society, in RVW Society Journal, number 66, June 2016.
The Exeter Philharmonic Choir's concert at Exeter Cathedral on 12 March, 2016 was all about the sea, culminating in Vaughan Williams' Sea Symphony.
But first a word about the première of a new work by the EPC's Director of Music, Andrew Millington composed specially for this occasion.
The Seafarer is a setting of a poem from the Exeter Book, the collection of Anglo-Saxon poetry kept in the Cathedral Library. As observed in the composer's programme note, the poem tells of the hardships of life at sea, in fact an allegory on the journey of life, with the text on this occasion interspersed with verses from the Psalms. At about 10 minutes in length, this short work is scored for baritone soloist, mixed chorus and orchestra. While not musically ambitious, the immediate impression was of an attractive work with very effective choral and orchestral colouring of the text and a sympathetic balance between the different forces; here was a real sense of the mood and movement of the sea. It could be a very useful addition to the repertoire of other choral societies. The composer led an authoritative first performance (with Julian Rippon as the baritone soloist) well received by the evening's audience. The Sinfonietta (led by Richard Studt) provided its customary support for Andrew Millington and the EPC throughout the concert, starting the evening off with a well-shaped reading of Mendelssohn's Calm Sea and Prosperous Voyage. The woodwind detail of the performance was a particular feature. But the biggest challenge for both choir and orchestra was the main work of the concert, the Sea Symphony. A mixture of the exuberant and the visionary, this large work is in part (like the Millington) about the journey of life, but set to the words of Walt Whitman, the American poet whose works were much admired by Vaughan Williams. From the contrast of the huge, dramatic opening to the second movement nocturne and beyond, the music passes through many changes of mood and difficulty to challenge the performers. The well-rehearsed choir rose confidently to the occasion even if occasionally, such as in the opening bars, it was swamped by the volume demanded in places by Vaughan Williams' extrovert orchestration. Elsewhere, the choir showed its sensitivity in the more reflective passages – a nice sense of sadness and resignation at the verse, 'Token of all brave captains' in the first movement, for instance. The difficult hurdle of the scherzo was well met by the choir, with the orchestra also showing its virtuosity here in the depiction of wind and spray. In Catherine Hamilton and Julian Rippon the performance had two fine soloists, especially well matched in the long duet of the final movement. Warm applause, well deserved, greeted the end of a most enjoyable concert – another feather in the cap for Andrew Millington and the EPC. David Batty
A note by the choir's former conductor, Raymond Calcraft
Can I also add my own particular congratulations and thanks to you all. There have been many excellent concerts under Andrew's direction since he became Conductor in 2003 but none finer than this. It made me extremely proud of my long association with the choir, which has rarely sounded quite as splendid as in this concert, which was a delight from start to finish. And I do hope we may have the opportunity to hear The Seafarer again before too long.


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A paper at the Graduate Student Conference
"Thinking the Present : The Beginnings and Ends of Political Theory" University of California, Berkeley
27-28 May 2005
Uri Gordon
Doctoral Candidate
Department of Politics and International Relations
University of Oxford
54 Percy st.
Oxford OX4 3AF
United Kingdom
Tel.: (+44) 1865-250274
Email: firstname.lastname@example.com
"Anarchy is not a thing of the future, but of the present; not a matter of demands, but of living".
– Gustav Landauer
Anarchism, in its re-emergence as a movement over the past decade, has been the site of manifold
reconfigurations that distinguish it from previous cycles of
left-libertarian political expression. Networked
structures replace formal federations and unions, a stronger emphasis is given to direct action and cultural
experimentation, and the target of resistance is generalised from state and capital to all forms of domination.
Yet another reconfiguration, less often mentioned by activists and commentators, is the unprecedented
grounding of anarchist political commitments in the present tense. Having by and large abandoned the
imagery of a "future anarchist society", contemporary anarchist political culture focuses its discourses of
resistance and liberation on the here and now. This paper examines several dimensions of this present-tense
orientation, with the view of strengthening our understanding of the relevance of anarchism to
contemporary political theory.
Keywords: Anarchism, Utopia, Prefigurative Politics, Direct Action, Individualism
1. Anarchism as a political culture
Let me begin by clarifying a few baseline understandings about what I mean by "anarchism". I view
anarchism first and foremost as a movement, whose form can today be described as a decentralised,
diverse and evolving network, providing communication and active
solidarity among autonomous
nodes of social struggle. This anarchist movement is "new" in the key respect that it does not owe its
roots solely to the historical anarchist movement, but rather represents the revival of anarchist values in
a broader intersection of movements, e.g. radical ecology, feminism, black and indigenous liberation,
anti-nuclear movements and, most recently, resistance to neoliberal capitalism and the global
permanent war. Because of its mongrel genealogy, anarchism in the age of globalisation is an
immensely diverse movement, open to many fresh ideas and experimenting with the possibilities and
challenges of a shifting landscape of struggle.
What animates this movement, the real ontos of anarchism, is anarchist political culture. Political
culture can be explained as a set of shared orientations towards "doing politics", wherein issues are
framed, strategies are legitimised and collective interaction takes on enough regularity to structure
members' mutual expectations. For heuristic purposes, we can view these orientations as they relate to
anarchism in four broad categories: organisational practices, methods of action, political language and
mythology. Organisationally this culture is manifest in network- and affinity group-based forms of
political mobilisation, displaying horizontal coordination among
autonomous direct participants,
consensus-based decision making, and the ideal of the free and open circulation of information. In
terms of action repertoires, anarchist political culture emphasises a "Do It Yourself" approach of direct
action, disinterest in operating through the system or building political power within it, a dual strategy
of confrontation to delegitimise the system and grassroots
alternative-building from below, and a
commitment to "being the change" on any level, form personal relationships that address sexism and
racism to sustainable living and communes. Shared political language has to do not only with common
terms and expressions in the activist "jargon", but also with the way these and other concepts are
thought to be related and connected to each-other. In other words, different political cultures have
different epistemologies – ways of organising their understanding of politics and making sense of
them. Mythologies, in the current sense, are the movement's orally transmitted stories (about past
mobilisations and the like), through which collective identity is
reproduced and which functio'n also as
a mobilising resource. Such are the narratives that spin a thread leading from Chiapas to Seattle, or
from Greenham Common to Porto Alegre.1
This familiar political culture is what animates anarchism in the present day, and gives it unity. It is
1 See Notes from Nowhere, eds. (2003), We Are Everywhere: The Irresistible rise of global anti-capitalism (London: Verso)
impossible to fully pin-down in universalist, philosophical formulations. If, however, we wanted for
practical purposes to express its "political" basics more concretely, we could look at the type of
language used in the various "hallmarks" and "principles of unity" that are clearly agreeable to
anarchists, such as those of the Peoples' Global Action and Indymedia networks, or of any number of
local groups and collectives. All of these emphasise two things. First, a rejection of all structures of
domination and systemic violence such as capitalism, the state, patriarchy and racism. Second, a
"prefigurative politics" that involves constructing concrete alternatives, especially in terms of social
relations. Prefigurative politics thus combines reference to both dual power strategies and to realising a
libertarian and egalitarian ethos in the movement's own structures, social dynamics and lifestyle.
2. Future? What future?
Now both these moments of anarchism partake in the mainspring of
anarchism's strong proposal
for a "present-tense" politics. Anarchism is unique among political movements in emphasising the
need to realise its desired social relations within the structures and practices of the revolutionary
movement itself. As such, prefigurative politics can be seen as a form of "constructive" direct action,
whereby anarchists who propose social relations bereft of hierarchy and domination undertake their
construction by themselves.
From a strategical perspective, the pursuit of prefigurative politics indicates most clearly a politic of
the here and now, and is seen by many anarchists as an inseparable aspect of their projects. This is
informed by a critique of reformist and authoritarian revolutionary models of social change. For the
latter to be successful, anarchists believe, the modes of organisation that will replace capitalism, the
state, gendered divisions of labour and so on need to be prepared
alongside (though not instead of) the
attack on present institutions. On such a reading, if people want a society that is characterised by nonhierarchical
cooperation and the erosion of dominatory institutions and behaviours, then such a society
directly proceeds from the realities that present-day movements develop. "The very process of building
an anarchist movement from below is viewed as the process of consociation, self-activity and selfmanagement
that must ultimately yield that revolutionary self that can act upon, change and manage
an authentic society".2
Anarchists by and large no longer tend to understand revolution, if they even use the term, as a
horizon event but as an ongoing process. This, as opposed to traditional anarchism's political
imaginary which unmistakably included the notion of revolution as an event, a moment of large scale
2 Murray Bookchin (1980), "Anarchism Past and Present", Comment 1:6 qualitative change in social life. Bakunin spoke of "a universal,
worldwide revolution...[the] formidable
reactionary coalition can be destroyed only by the greater power of the simultaneous revolutionary
alliance and action of all the people of the civilized world".3 It is certainly true that anarchists carried
this view of revolution one step away from gross millenarianism, by insisting that the revolutionary
horizon can be and was traversed during exceptional moments. The Paris Commune of 1871, the Italian
factory occupations of 1919-1920, the Spanish Revolution of 1936 and the French May 1968 uprisings
are the most obvious examples of events that were interpreted by
anarchists in this way, with their
transience and localisation doing nothing to diminish their qualitative significance.4 Still, these were
exceptional moments. The ultimate failure of these events and the
deterioration of rare revolutionary
"successes" into authoritarian nightmares debased the coin of Revolution for anarchist movement.
With the re-emergence of anarchism in later decades, the revolutionary horizon would become more
and more attracted into the present tense, culminating in its complete absorption as a potential
dimension of everyday life. Colin Ward's focus on the pedestrian
interactions which functio'n without
hierarchy and alienation, and the many Situationist-influenced
explorations of an anarchist micropolitics
of resistance and reconstruction in everyday life, are prominent
contributions to this process.5
In the words of U.S. anarchist publishing collective CrimethInc.,
Our revolution must be an immediate revolution in our daily lives; anything else is not a revolution but a
demand that once again people do what they do not want to do and hope that this time, somehow, the
compensation will be enough. Those who assume, often unconsciously, that it is impossible to achieve
their own desires – and thus, that it is futile to fight for themselves – often end up fighting for an ideal or
cause instead. But it is still possible to fight for ourselves, or at least the experiment must be worth a try; so
it is crucial that we seek change not in the name of some doctrine or grand cause, but on behalf of
ourselves, so that we will be able to live more meaningful lives.
Similarly we must seek first and foremost
to alter the contents of our own lives in a revolutionary manner, rather than direct our struggle towards
world-historical changes which we will not live to witness. In this way we will avoid the feelings of
worthlessness and alienation that result from believing that it is necessary to "sacrifice oneself for the
cause", and instead live to experience the fruits of our labors…in our labors themselves.6
3 Mikhail Bakunin (1866), "The Revolutionary Catechism", in Sam Dolgoff (ed., 1971) Bakunin on Anarchy (New York:
4 Mikhail Bakunin (1871), The Paris Commune and the Idea of the State (New York: Alfred A. Knopf); Errico Malatesta (ed.
Vernon Richards, 1965), Life and Ideas (London: Freedom Press), p. 134; Murray Bookchin (1994), To Remember Spain:
The Anarchist and Syndicalist Revolution of 1936 (Edinburgh: A.K. Press); Roger Gregoire and Fredy Perlman (1970),
Worker-Student Action Committees, France May '68 (Detroit: Black & Red), §§14, 16, 22; Murray Bookchin (1971), "The
May-June events in France I: A Movement for Life", in Post-scarcity Anarchism (Montreal, Black Rose Books).
5 Colin Ward (1973), Anarchy in Action (London: Allen and Unwin); Raoul Vaneigm (1983), The Revolution of Everyday
Life (London: Left Bank Books and Rebel Press).
6 CrimethInc. (2001), "Alive in the Land of the Dead",
Is such an approach sustainable? What kind of political understandings can ground it, beyond just
"explaining" it on the level of social movements' construction of
"collective action frameworks"? And
what significance does this present-tense orientation have for the concrete choices that anarchists make
about their political projects, as well as about the sensibilities ? 3. Two pessimistic arguments against Utopia
Let me then examine what I believe is the mainspring of anarchism's present-tense orientation: an
open-ended tendency, one that eschews the rhetoric of a post-revolutionary resting point. Now the
basic idea is not new, and was expressed with increasing strength by anarchists throughout the
twentieth century. To Landauer's epigram in the opening of this essay may be added this statement by
Rudolf Rocker:
Anarchism is no patent solution for all human problems, no Utopia of a perfect social order, as it has so
often been called, since on principle it rejects all absolute schemes and concepts. It does not believe in any
absolute truth, or in definite final goals for human development, but in an unlimited perfectibility of social
arrangements and human living conditions, which are always straining after higher forms of expression,
and to which for this reason one can assign no definite terminus nor set any fixed goal.7
Rocker bases his anti-utopian stance, on the one hand, on the refusal of absolutes, and on the other
on the assertion that social arrangements display an inherent proclivity for change. For him, however,
the change in question is regarded in optimistic terms – it tends towards improvement, and for this
reason cannot be limited in scope. What I want to do now is to offer two different arguments, of a more
pessimistic character, which I think substantiate the anti-utopian stance that animates the
contemporary movement. Both arguments are geared towards an understanding that even the most
thoroughgoing realisation of anarchist social transformation does not amount to a culmination of the
anarchist project.
It should be clarified that the pessimism of these arguments is not related to the oft-forwarded
claims that anarchism is impossible due to an inherently selfish,
competitive and/or malevolent human
nature. To this anarchists need only reply with their own familiar arguments, referring to the
complexity of human beings and to the importance of social relations for shaping our behaviour and
selfhood, as well as in-your-face "state of nature" arguments drawing on anthropological evidence.
However, by invoking an inherent instability of individual human
behaviour, or by anticipating a
7 Rudolf Rocker (1938/1989) "Anarchism: Its Aims and Purposes", in Anarcho-Syndicalism (London: Pluto), p.30
constant flux of relationships between diverse and decentralised
communities, anarchists are in fact
also denying their project the possibility of utopian stability. Here the first pessimistic argument can be
forwarded: it is impossible to be sure that even under whatever conditions anarchists would consider
as most fruitful to sociability and cooperation, some individuals and groups might not successfully
renew patterns of exploitation and domination in society. This type of argument has long been evaded
by many anarchists, who have endorsed the expectation inspired by
Kropotkin, that a revolution in
social, economic and political conditions would encourage an essentially different patterning of human
behaviour – either because it would now be able to flower freely under nurturing conditions, or
because revolution would remove all hindrances to the development of human beings' cooperative /
egalitarian / benevolent side. Peter Marshall has argued in this vein that "it is not only the mind but
also our emotional and sexual drives which regulate themselves when not interfered with by artificial
restrictions imposed by coercive institutions"8.
Others, however, have heeded the warning and internalised it to a certain extent. Let me look at two
examples of recent anarchist-inspired works which have done so. The first is Ursula Le Guin's novel The
Dispossessed, perhaps the most honest attempt at portraying a functio'ning anarchist society. Referring to
the work as an "anarchist utopia", however, is misleading precisely for this reason, since the society it deals
with is far from perfect or unproblematic. The protagonist, Shevek, is driven to leave his anarchist society on
the moon of Anarres, not because he rejects its core anarchist ideals but because he sees that some of them
are no longer adequately reflected in practice, while others need to be revised in order to give more place to
individuality. In the hundred and seventy years since its establishment, following the secession of a mass of
revolutionary anarchists from the home-planet of Urras, Anarresti society has witnessed the growth of
xenophobia, informal hierarchies in the administrative syndicates, and an apparatus of social control
through custom and peer pressure. All of these contribute to a conformity that hinders Shevek's selfrealisation
in his pursuit of his life project, the development of a ground-breaking approach in theoretical
physics. Shevek embodies the continuing importance of dissent even after the abolition of capitalism and
government. Through his departure and founding of the Syndicate of Initiative, he becomes a revolutionary
within the revolution and initiates change within the anarchist society: "It was our purpose all along – our Syndicate, this journey of mine – to shake up things, to stir up, to break
some habits, to make people ask questions. To behave like anarchists!"9 Shevek's project renews the spirit of dissent and non-conformism that animated the original
creation of the anarchist society on Anarres in the first place. As Raymond Williams observes, this
8 Peter Marshall (1992), Demanding the Impossible (New York: Fontana) 9 Ursula Le Guin (1974/2002) The Dispossessed (Lodnon: Gollancz), p.316 dynamic portrays The Dispossessed as "an open utopia: forced open, after the congealing of ideals, the
degeneration of mutuality into conservatism; shifted, deliberately, from its achieved harmonious
condition, the stasis in which the classical utopian mode culminates, to restless, open, risk-taking
In addition to Le Guin's novel, we may look to evidence of this
realisation in the anarchist-inspired
vision of an alternative society forwarded in the book bolo'bolo by the Zurich-based writer P.M.. Again
the application of the word "utopia" to this book is misleading, since it not only acknowledges but
treasures the type on instability and diversity of social relations that can be ushered in by the removal
of all external control on the behaviour of individuals and groups. The world anti-system called
bolo'bolo is a mozaic in which every community (bolo) of around five hundred residents is as
nutritionally self-sufficient as possible, and has complete autonomy to define its ethos or "flavour"
(nima). Stability is afforded by a minimal but universal social contract (sila), enforced by reputation and
interdependence. This contract guarantees, for example, that every individual (ibu) can at any time
leave their native bolo, and is entitled to one day's rations (yalu) and housing (gano) as well as medical
treatment (bete) at any bolo. It even suggests a duel code (yaka) to solve disputes between individuals
and groups".11 However,
There are no humanist, liberal or democratic laws or rules about the content of nimas and there is no State
to enforce them. Nobody can prevent a bolo from committing mass suicide, dying of drug experiments,
driving itself into madness or being unhappy under a violent regime. Bolos with a bandit-nima could
terrorize whole regions or continents, as the Huns or Vikings did. Freedom and adventure, generalized
terrorism, the law of the club, raids, tribal wars, vendettas, plundering – everything goes.12
While most anarchists might not want to go that far, the point here is that if this is the case, then any
anarchist theory which acknowledges the absence of law and authority must also respond to the
possibility of a re-emergence of patterns of domination within and/or among communities, even if at a
certain point in time they have been consciously overcome. Thus, on one interpretation, anarchists have
been drawn to regard the ultimate telos of opposition to domination as utopian fantasy, accepting that
"eternal vigilance is the price of liberty".13
If the first argument challenges the achievability of an anarchist "post-revolutionary resting point",
the second one questions it on the conceptual level. It is close to what I think Noam Chomsky has in
10 Raymond Williams (1978), "Utopia and Science Fiction" Science Fiction Studies 5:3
11 P.M. (1985), bolo'bolo (New York: Autonomedia), pp.68-70
12 bolo'bolo, pp.77-8
13 This saying has been attributed, in various phrasings, to Edmund Burke, President Andrew Jackson and abolitionist
Wendell Phillips.
mind with his remark that anarchism constitutes "an unending struggle, since progress in achieving a
more just society will lead to new insight and understanding of forms of oppression that may be
concealed in traditional practice and consciousness".14 The generalisation of anarchist resistance to
encapsulate not only the state and capital but all forms of domination in society – patterns of systematic
inequality and exclusion such as patriarchy, racism and heterosexism – moves its notions of social
transformation beyond their previous formulation as the replacement of institutions to the redefinition of
social patterns in all spheres of life. However, such a generalisation also means a shift in the understanding
of the horizons of the anarchist project. While it has been possible to speak within a coherent framework
about the abolition of institutions, the way in which anarchists have come to conceptualise domination
(under the influence of critiques emanating from radical feminist, anti-racist and queer liberation
movements) presents it with a concept to which the idea of abolition is not so easily attached. On such a
reading, in fact, a condition without any form of domination or
discrimination in society is literally
unthinkable. This is because in order to speak of the abolition of domination, we need to have access to
its total picture, to the entire range of possible patterns of social inequality and exclusion – and we can
never be sure that we have such a complete picture.
To clarify this, think for a moment about the ideals said to have animated the U.S. Declaration of
Independence, as present in famous passages such as "We hold these truths to be self-evident, that all
men are created equal" etc. Even with "people" replacing "men", this passage justly strikes us today as
irredeemably hypocritical. Dr. Johnson was the first to puncture the pretensions of American
revolutionaries when he pointed to the bitter irony "that we hear the loudest yelps for liberty among
the drivers of Negroes".15 Thomas Jefferson was, after all, a slave holder, as were many of the other
signatories to the Declaration. They were all representatives of most prosperous section of the colonial
elite, their wealth resting not only on slavery but also on the genocidal dispossession of North
America's indigenous peoples. And they had no intention of realising these "natural" to women.
However, while hypocrisy or voluntary blindness can seem to be obvious explanations in hindsight,
it is not certain that everything is attributable to such factors. We can still ask with honesty whether the
American "Founding Fathers" truly realised, amid their declarations of freedom and equality, that
Africans and Indigenous Americans were human beings, and that slavery, genocide and the denial of
rights to women stood in stark contradiction to their own declared principles. Even if it does seem
impossible to us that they did not, can we safely say the same about their attitudes to other forms of
discrimination that are blatantly evident to us today, such as those against children? Few people are
aware that until the 1880s the age of sexual consent for women in the U.S. was ten, and that the first
14 Noam Chomsky (1986), "The Soviet Union versus Socialism", Our
Generation 17:2, pp. 47-52.
15 Samuel Johnson (1775/1913), "Taxation no Tyranny", in The Works of Samuel Johnson (Troy, NY: Pafraets), vol.14,
pp.93-144. Anecdotally, in the same essay Johnson refers to the American secessionists as "those zealots of anarchy"
state legislation in protection for children was passed only in 1875 (in New York). And what of the only
recent recognition that "mentally disabled" people are not inferior, or that non-heterosexual practices
are not sinful and unnatural? In light of what seems to have been an utter unawareness to such axes of
inequality and oppression, it seems not entirely unlikely that such forms of domination as were entirely
"off the radar" for people in the past.
This leads to the crux of my second argument: How can we know that there are no forms of
domination that remain hidden from us today, just as some that we do recognise were hidden from our
predecessors? If we are at least prepared to entertain doubt on this matter, then we can no longer put
ourselves in a position from which we can speak with any coherence about the abolition of all forms of
domination. Here the objection that the writers of the Declaration of Independence were far from
anarchists is irrelevant, since the history of anarchist movement is just as embarrassing in this respect.
Instances of outright bigotry surrounding racism, sexism and homophobia are more abundant in
anarchist literature than many anarchists would care to recall. Pierre Joseph Proudhon was, on any
modern assessment, a despicable misogynist and anti-Semite. "Man's primary condition is to dominate
his wife and to be the master", he wrote, while "women know enough if the know how to mend our
socks and fix our steaks".16 "The Jew", moreover, "is the enemy of humankind. It is necessary to send
this race back to Asia, or exterminate it".17 Bakunin's writings are also famously rife with anti-Semitic
and anti-German attitudes.18 Kropotkin and many other Russian anarchists supported the first World
War.19 And as late as 1935 the prominent Spanish anarchist periodical Revista Blanca could still carry
the following, typically homophobic, editorial response to the question "What is there to be said about
those comrades who themselves are anarchists and who associate with inverts [sic]?":
They cannot be viewed as men if that "associate" means anything apart from speaking to or saluting
sexual degenerates. If you are an anarchist, that means that you are more morally upright and physically
strong than the average man. And he who likes inverts is no real man, and is therefore no real anarchist.20
Although nobody chooses their ideological ancestors, such statements should nevertheless compel
16 Pierre Joseph Proudhon (1875), Pornocracy, or Women of Modern Times – unpublished fragment, cited in Edward
Hyams (1979), Proudhon: His Revolutionary Life, Mind and Works (London: John Murray), p. 274. On Proudhon's
vituperative replies to contemporary feminists Georges Sand and Juliette Adam see Antony Copley (1989), "Pierre-
Joseph Proudhon: A Reassessment of his role as a Moralist", French History 3:2
17 Pierre Joseph Proudhon (1843-64), Les Carnets, in Selected Writings (ed. Stewart Edwards), p.228n
18 Mikhail Bakunin (1873), Statism and Anarchy (Cambridge: Cambridge University Press), pp.104ff and 175ff.
19 Paul Avrich (1967), The Russian Anarchists (Princeton: Princeton University Press), pp.118-119
20 Cited in Richard Cleminson (1995), "Male Inverts and Homosexuals: Sex Discourse in the Anarchist Revista Blanca",
in Gert Hekma et. al. (eds.), Gay Men and the Sexual History of the Political Left (Binghamton, NY: Haworth Press),
anarchists to endorse a healthy scepticism about the comprehensiveness of their own, contemporary
accounts of domination. As a result, the idea of an end to all forms of domination becomes, to use a
somewhat bombastic philosophical expression, an epistemological
impossibility. We cannot think such
a state of affairs since we do not possess the full list of features that are supposed to be absent from it,
let alone being capable of speaking of the forms of social life that might replace them. Admittedly, we
might have a better idea about forms of domination today simply because there are more voices
expressing them. Movements endorsing indigenous, queer, and youth
liberation have taken their place
much more vividly in the public sphere over recent years, and thus contributed to the articulation of
resistance to domination in forms that have not been explored before. But this is not enough to ensure
us that all possible axes along which domination operates have been exposed.
4. Anarchist Individualism Redux
As a closing thought, let me look at an important implication of this view for anarchist visions of
social transformation. If we insist on the potential need for anarchist agency under any conditions, then
the notion of an "anarchist society" as an achievable goal loses its meaning. To be sure, the frequency of
the need to exercise such agency may hopefully diminish to a great extent, in comparison to what an
anarchist approach would deem necessary in present societies, but we have no reason to think that it
can ever be permanently removed. Where does such a state of affairs leave anarchists today?
The primary conclusion that I think anarchists can (and often do) draw form the dissociation of their
project form a utopian horizon, and the transposition of their notion of social revolution to the presenttense,
is to revitalise the individualist commitments of social anarchism, elevating projects of selfrealisation
and the liberation of desire to a pivotal place in the process of social transformation.
As the anarchist revolutionary horizon constricts itself into the present tense, revolutionary
commitments, in turn, come to reflect and respond to the aspirations of living, experiencing
individuals. Utterances that militate against the individual's unfreedom and celebrate her or his selfrealisation
are no longer content to do so in the abstract. They must insist on the centrality of immediate
liberation, to the extent to which it can be achieved, in order to have any relevance for an anarchist
"revolution in everyday life". At the same time, the re-contextualisation of anarchist individualism in
the present tense and its concretion in empirical subjects reflects back on its (anti-)political content. An
anarchist individualism which demands realisation within society as it exists today, rather than as it
could be, defines its realisation as-against this existing society and serves as an immediate motivation
for action.
Anarchists are increasingly stressing that the point of their struggles is not only to help bring about
social transformation along anarchist lines, but also to liberate
themselves to the greatest degree
possible. On such a reading, a central motivation for anarchist action – not least so in its prefigurative
idiom – lies in the desire to inhabit, to the greatest extent possible, social relations that approximate
anarchists' ideals for society as a whole. Hence personal liberation and the confrontation with a
homogenising and oppressive social order can be seen to each supply the other's motivation: the
individual's own experience of restriction supplies a direct impulse for social action, whereas the
experience of struggle itself becomes a site of present-tense liberation. The revolution is now, and we must let the desires we have about the future manifest themselves in the
here and now as best as we can. When we start doing that, we stop fighting for some abstract condition for
the future and instead start fighting to see those desires realized in the present. Through this process we
start pushing back the veil of submission and domination towards the periphery of our lives, we start
reclaiming control over our own lives...Whether the project is a squat, a sharing of free food, an act of
sabotage, a pirate radio station, a periodical, a demonstration, or an attack against one of the institutions of
domination, it will not be entered into as a political obligation, but as a part of the life one is striving to
create, as a flowering of one's self-determined existence.21
Feeding back into such an individualist grounding , we can say that anarchist modes of interaction –
non-hierarchical, voluntary, cooperative, solidaric and playful – are no longer seen as features on which
to model a future society, but rather as an ever-present potential of social interaction here and now.
Such an approach promotes anarchy as culture, as a lived reality that pops up everywhere in new
guises, adapts to different cultural climates, and should be extended and developed experimentally for
its own sake, whether or not we believe it can become, in some sense, the prevailing mode of society.
Also, it amounts to promoting the view of anarchy as a feature of everyday life, in mundane settings
such as "a quilting bee, a dinner party, a black market...a neighborhood protection society, an
enthusiasts' club, a nude beach".22 The task for anarchists, then, is not to introduce a new society but to
realise an alternative society as much as possible in the present tense. 21 Terrence Hodgson, "Towards Anarchy", online at
http://groups.msn.com/AnarchistAlliance/ towardsanarchy.msnw
22 Hakim Bey (1991), "The Willimantic/Rensselaer Questions", in Mike Gunderloy and Michael Ziesing, Anarchy and
the End of History (San Francisco: Factsheet Five Books), pp.87-92


text:
"Striking opaque purple color, and a stunning nose of cherry liqueur intertwined with prunes, black currants, coffee, smoke, and blackberries." – Erin Green, Winemaker 2001
69% Cabernet Sauvignon
27% Merlot
2% Cabernet Franc
1% Petit Verdot
1% Malbec
- Martinelli,
- Thorevilos,
- Rancho Chimiles,
- Moon Vineyard
Proprietary Red: An Iconic Napa Valley Bordeaux Blend
Jayson Pahlmeyer's "California Mouton" - a rich, powerful Napa Valley Bordeaux blend called Proprietary RedRead More
94 Points
James Laube, Wine Spectator, November 2002
Ultra-ripe, pushing it to the max. Rich mocha-laced black cherry and blackberry fruit. Hints of milk chocolate, herb and currant. Finishes with smooth, plush tannins and excellent length and complexity.
94 Points
Stephen Tanzer, International Wine Cellar, May/June 2002
Bright, full medium ruby. Subdued but highly complex nose melds black raspberry, blueberry, plum, licorice, mocha, leather and tar. Offers compelling sweetness and density, with sharply focused flavors of black fruits, minerals and roast coffee, but comes across as less expressive today than the merlot, and still tight on the back half. But a wine of outstanding breadth and persistence, deeper and sweeter than the 2000. Tannins are substantial but quite fine.
90 Points
Robert Parker, Wine Advocate #142, August 2002
A dense purple color accompanies its sweet nose of crème de cassis intermixed with smoky, toasty oak, tar and earth. While it leans toward a more austere, Bordeaux-like style, it possesses more glycerin, alcohol and depth than most ripe Bordeaux. The finish exhibits chocolate and black currant flavors, plenty of sweetness, and austere tannin. Drink it over the next 14-15 years.
- Winemaker:
- Erin Green
- Alcohol:
- 14.0%
- Released:
- October 1, 2002
Harvested at the end of October, this wine was aged in 100% new French oak barrels for 18 months.


text:
Airline Finds Incredible Way To Turn Crying Babies On Flights Into A Positive
There's no sound worse than a baby crying in public – and it's even worse when you're sitting next to one on a plane.
While many people have come to associate flying with frustration because of crying kids, American airline JetBlue had passengers singing a different tune on a recent flight from New York to Long Beach, California.
In their 'FlyBabies' promotional video, JetBlue detailed the difficulties of flying with a baby from a mother or father's perspective – with most parents worried their children would get tired and fussy mid-flight, upsetting other passengers. So the airline decided to turn this into a positive.
Every time a baby cried on the flight to California, JetBlue would offer 25 per cent off each passenger's next flight. There were five babies on board – so the chances of a free flight were pretty good.
And in the end, all it took were four cries for the 140 passengers to be rewarded with a free roundtrip ticket on JetBlue.
Unfortunately though, it was a one time deal for passengers on board the California bound flight. But maybe other airlines will jump on the free flights band wagon.
Crying babies never sounded so good.
Watch the full video here:


text: The curfew is expected to be lifted later on Friday The curfew, imposed late on Thursday on the entire Jaffna Peninsula, the home of most of the island's 3.2 million Tamils, was expected to be lifted later on Friday, said police spokesman Reins Pourer. The violence was sparked on Thursday when a soldier's gun accidentally discharged while he was trying to get a haircut at a barber shop just outside the town of Jaffna, 300km north of the capital Colombo, police said. The bullet killed an employee, and the soldier was arrested. Furious residents on Thursday burnt tires, stoned military vehicles and seized police Superintendent Charles Wijewardene, who arrived to investigate the incident. His body was later found lying on the street, covered with stab wounds. He was the most senior police officer to be killed since the government and Tamil rebels signed a ceasefire three years ago. Sri Lanka's police top brass flew to Jaffna on Friday to review the situation. Residents contacted by telephone said the area remained tense. Jaffna is the scene of two decades of fighting between government troops and Tamil Tiger rebels. SOURCE: AFP


text:
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UK data driving real-world evidence
Research using CPRD data has informed drug safety guidance and clinical practice and resulted in over 2,500 peer-reviewed publications. The CPRD bibliography is updated on a monthly basis (last updated 5 August 2020) and papers are listed below and in the PDF below.
If you have published papers using CPRD data which are not included in this list, please contact us at email@example.com so that we can update the bibliography.
This work uses data provided by patients and collected by the NHS as part of their care and support. CPRD encourages researchers to use this citation in all publications using CPRD data. Find out more about acknowledging the use of patient data at the Understanding Patient Data website.
"Ability of primary care health databases to assess medicinal products discussed by the European Union Pharmacovigilance Risk Assessment Committee", Clin Pharmacol Ther, 2020.,
"Adaptive Treatment Strategies with Survival Outcomes: An Application to the Treatment of Type 2 Diabetes using a Large Observational Database", Am J Epidemiol, 2020.,
"Adequacy of Therapy for People with Both COPD and Heart Failure in the UK: Historical Cohort Study", Pragmat Obs Res, vol. 11, pp. 55-66, 2020.,
"Adverse pregnancy outcomes and subsequent development of connective tissue disease in the UK: an epidemiological study", Bjog, 2020.,
"Age-, sex- and ethnicity-related differences in body weight, blood pressure, HbA(1c) and lipid levels at the diagnosis of type 2 diabetes relative to people without diabetes", Diabetologia, 2020.,
"Antibiotic use and serious complications following acute otitis media and acute sinusitis: a retrospective cohort study", Br J Gen Pract, vol. 70, pp. e255-e263, 2020.,
"Approaches for the identification of chronic kidney disease in CPRD-HES-linked studies", J Comp Eff Res, 2020.,
"Aromatase Inhibitors and the Risk of Cardiovascular Outcomes in Women With Breast Cancer: A Population-Based Cohort Study", Circulation, vol. 141, pp. 549-559, 2020.,
"Association Between an Acute, Drug-Induced Decrease in High-Density Lipoprotein Cholesterol Levels and Risk of Cardiovascular Events", Clin Drug Investig, 2020.,
"Association between chronic kidney disease and incident diagnosis of dementia in England: a cohort study in Clinical Practice Research Datalink", BMJ Open, vol. 10, p. e033811, 2020.,
"Association between COPD exacerbations and lung function decline during maintenance therapy", Thorax, 2020.,
"The Association between Oral Anticoagulants and Cancer Incidence among Individuals with Nonvalvular Atrial Fibrillation", Thromb Haemost, 2020.,
"The association between partner bereavement and melanoma: cohort studies in the U.K. and Denmark", Br J Dermatol, 2020.,
"Association between pre-diabetes and microvascular and macrovascular disease in newly diagnosed type 2 diabetes", BMJ Open Diabetes Res Care, vol. 8, 2020.,
"The association between primary care quality and health-care use, costs and outcomes for people with serious mental illness: a retrospective observational study", in Health Services and Delivery Research, Southampton (UK): NIHR Journals Library Copyright © Queen's Printer and Controller of HMSO 2020. This work was produced by Jacobs et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This issue may be freely rep, 2020.,
"The association between unexpected weight loss and cancer diagnosis in primary care: a matched cohort analysis of 65,000 presentations", Br J Cancer, 2020.,
"Associations between macrolide antibiotics prescribing during pregnancy and adverse child outcomes in the UK: population based cohort study", Bmj, vol. 368, p. m331, 2020.,
"Asthma-Related Health Outcomes Associated with Short-Acting β(2)-Agonist Inhaler Use: An Observational UK Study as Part of the SABINA Global Program", Adv Ther, 2020.,
"Beta 2 agonists and the incidence of Parkinson's disease", Am J Epidemiol, 2020.,
"Blood pressure in frail older adults: associations with cardiovascular outcomes and all-cause mortality", Age Ageing, 2020.,
"Burden of asthma exacerbations and health care utilization in pediatric patients with asthma in the US and England", Immun Inflamm Dis, 2020.,
"Burden of disease from shingles and post-herpetic neuralgia in the over 80 year olds in the UK", PLoS One, vol. 15, p. e0229224, 2020.,
"Can the Use of Bayesian Analysis Methods Correct for Incompleteness in Electronic Health Records Diagnosis Data? Development of a Novel Method Using Simulated and Real-Life Clinical Data", Front Public Health, vol. 8, p. 54, 2020.,
"Cancer incidence following a high-normal platelet count: cohort study using electronic healthcare records from English primary care", Br J Gen Pract, 2020.,
"Cardiotoxicity of Sequential Aromatase Inhibitors Use in Women with Breast Cancer", Am J Epidemiol, 2020.,
"Changes in the presenting symptoms of lung cancer from 2000-2017: a serial cross-sectional study of observational records in UK primary care", Br J Gen Pract, 2020.,
"Channeling Bias in the Analysis of Risk of Myocardial Infarction, Stroke, Gastrointestinal Bleeding, and Acute Renal Failure with the Use of Paracetamol Compared with Ibuprofen", Drug Saf, 2020.,
"Characteristics, service use and mortality of clusters of multimorbid patients in England: a population-based study", BMC Med, vol. 18, p. 78, 2020.,
"Comorbidities in patients with polymyalgia rheumatica prior to and following diagnosis: A case control and cohort study", Semin Arthritis Rheum, vol. 50, pp. 663-672, 2020.,
"Comparative effects of sulfonylureas, DPP4is and SGLT2 inhibitors added to metformin monotherapy: a propensity-score matched cohort study in UK primary care", Diabetes Obes Metab, 2020.,
"Comparing healthcare cost associated with the use of enzyme-inducing and non-enzyme active antiepileptic drugs in elderly patients with epilepsy in the UK: a long-term retrospective, matched cohort study", BMC Neurol, vol. 20, p. 7, 2020.,
"Comparison of antibiotic prescribing records in two UK primary care electronic health record systems: cohort study using CPRD GOLD and CPRD Aurum databases", BMJ Open, vol. 10, p. e038767, 2020.,
"Comparison of long-term use of prolonged-release ropinirole and immediate-release dopamine agonists in an observational study in patients with Parkinson's disease", Pharmacoepidemiol Drug Saf, 2020.,
"Comparisons of Staphylococcus aureus infection and other outcomes between users of angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers: lessons for COVID-19 from a nationwide cohort study", Wellcome Open Res, vol. 5, p. 77, 2020.,
"Data-driven discovery of changes in clinical code usage over time: a case-study on changes in cardiovascular disease recording in two English electronic health records databases (2001-2015)", BMJ Open, vol. 10, p. e034396, 2020.,
"Deep learning for electronic health records: A comparative review of multiple deep neural architectures", J Biomed Inform, vol. 101, p. 103337, 2020.,
"Delays in referral from primary care worsen survival for patients with colorectal cancer: a retrospective cohort study", Br J Gen Pract, vol. 70, pp. e463-e471, 2020.,
"Development and Validation of a Clinical Prediction Tool for Seasonal Influenza Vaccination in England", JAMA Netw Open, vol. 3, p. e207743, 2020.,
"Development and validation of a multivariable prediction model for infection-related complications in patients with common infections in UK primary care and the extent of risk-based prescribing of antibiotics", BMC Med, vol. 18, p. 118, 2020.,
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"Development and validation of the DIabetes Severity SCOre (DISSCO) in 139 626 individuals with type 2 diabetes: a retrospective cohort study", BMJ Open Diabetes Res Care, vol. 8, 2020.,
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"Disease Activity in Inflammatory Bowel Disease Is Associated With Arterial Vascular Disease", Inflamm Bowel Dis, 2020.,
"Effect of bariatric surgery on long-term cardiovascular outcomes: a nationwide nested cohort study", Eur Heart J, 2020.,
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"Effect of pre-existing conditions on bladder cancer stage at diagnosis: a cohort study using electronic primary care records in the UK", Br J Gen Pract, 2020.,
"The effectiveness of frequent antibiotic use in reducing the risk of infection-related hospital admissions: results from two large population-based cohorts", BMC Med, vol. 18, p. 40, 2020.,
"Effectiveness of inactivated influenza vaccine in autoimmune rheumatic diseases treated with disease-modifying anti-rheumatic drugs", Rheumatology (Oxford), 2020.,
"Eleven-year multimorbidity burden among 637 255 people with and without type 2 diabetes: a population-based study using primary care and linked hospitalisation data", BMJ Open, vol. 10, p. e033866, 2020.,