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SAN JOSE, Calif. - Three hikers stranded on a glacier in Alaska, their tent ruined by high winds, were rescued after they alerted a friend by using a satellite-based texting device that works at every end of the globe. With the weather deteriorating and hypothermia setting in, the hikers might not have survived otherwise.
SAN JOSE, Calif. - Three hikers stranded on a glacier in Alaska, their tent ruined by high winds, were rescued after they alerted a friend by using a satellite-based texting device that works at every end of the globe. With the weather deteriorating and hypothermia setting in, the hikers might not have survived otherwise.
A hiker in the Sierra Nevada sent an SOS alert using a similar device, and rescuers arrived in full force. When asked what the emergency was, the hiker said he thought he saw a wolf. The Sierra Nevada has no wolves.
The influx of technology in the backcountry has been both a godsend to hikers and a headache for rescue crews.
As tech for the wilderness becomes more sophisticated and lighter to carry, more backpackers and long-distance hikers have access to lifesaving devices, but the security these high-tech gadgets provide are persuading more novices to tackle rugged adventures for which they are ill-prepared, wilderness leaders say.
"They tend to become Superman on the trail, and they tend to put themselves at greater risk because they have this device," said Steve Wood, outdoor-programs manager for REI in the San Francisco Bay Area.
"People are going off the trail or going deeper into the wilderness when they don't have the skills to do so," Wood said.
No technology replaces basic map-reading and compass skills, survival experts say, and a high-tech gadget is no substitute for fire starters and an emergency blanket. But, when used correctly, high-tech backcountry gear can turn potentially fatal situations into mere inconveniences.
Backpackers and outdoor adventurers can choose among a growing crop of navigation devices, beacons and texting devices that use either military or commercial satellites and will send a message from just about anywhere.
Personal locator beacons are the most common group of gadgets and have long been used by ships and the military. When a beacon is activated, the Air Force is notified and coordinates with the closest search-and-rescue team to dispatch volunteers.
"I haven't seen a situation where we haven't been able to locate the person in very short order," said Matthew Scharper, deputy chief and state search-and-rescue coordinator at the California Governor's Office of Emergency Services.
But, he added, "There is no guarantee of rescue, especially in bad weather. You have to be prepared for the environment. You have to be self-sufficient."
As is true of any other technology, personal locator beacons can fail. In February, a woman with extensive mountaineering experience activated her beacon a short way into an ambitious New Hampshire hike, but the signals were off the mark, probably affected by temperatures lower than the device's minus-4 degree limit, according to news reports. The GPS coordinates were so far off that they sent rescue crews to the opposite side of the mountain from Kate Matrosova, 32, who died of exposure.
"I have to wonder if her decision to take such little survival gear was based on the fact that she thought she could be quickly rescued," said Jason Schwartz, a survival expert and founder and senior editor of Rocky Mountain Bushcraft, a survival blog.
"Or maybe that her handheld GPS unit would guide her back down, and she wouldn't need to
worry about stopping to make shelter to ride out the storm. This is a tragic example of why your wits, sound judgment, experience and carrying the necessary survival gear always trump technology in a survival situation."
More-complex technology known as global satellite communicators combine navigation, messaging and SOS alerts into one device.
SPOT, one of the best-known technologies in this category, runs on a private satellite network and allows backpackers to send messages to family and friends and post their route to the Web for others to track. It also has a "help" button that will alert family and friends of a minor problem, and an "SOS" button that will alert emergency-response teams. The hiker can't receive messages.
The company says SPOT devices are responsible for more than 3,500 rescues in the past seven years, and about 500,000 SPOT gadgets are in use.
Some backpackers, however, say the signal is unreliable; they sent messages that were never received, and the GPS didn't always recognize their location.
Experts worry that these devices result in a strain on search-and-rescue teams and taxpayers.
"People are getting these devices, they push the button and expect the government to get them out of trouble that they never should have been in in the first place," Scharper said. "It's having a huge impact upon search-and-rescue teams, upon the sheriff and upon the National Park Service."


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Why you are never too old to learn ICT skills
"I compare it with illiteracy. If you're not able to use the Internet nowadays, you are like somebody who can't read or write" ~ Participant on the ECDL & Age Action Ireland
The benefits for older people to learn digital skills
The Internet has become a fundamental part of 21st century life, and means of accessing goods, services, information and communication. More and more governments are delivering public services online, and day-to-day services such as banking are shifting online. Those without access to the internet will find it increasingly harder to access such services.
The 2013 CARDI report pointed out that there are multiple benefits to older people getting online, such as the ability to make "better-informed decisions through providing easy access to information on goods and services" and "that using the internet can have clear and quantifiable economic and social benefits"
Their study found that 50% of older adults who had received formal ICT training were more likely to go online to use public services afterwards.
Spending time online has also been proven to be effective in warding off depression and loneliness in retirees, according to research by The Gerontological Society of America. The research said "that Internet use reduced the probability of a depressed state by 33 percent among their study sample."
How training has helped older people
In order for citizens to get the benefits of such access, they need the requisite equipment and digital skills. The 2013 CARDI report pointed out that "ICT training and support is critical in supporting older people's development of 'internet self-efficacy'.
This video on the Age Action Ireland e-Citizen certification course is a good illustration of the type of training that can suit older people, and how it can help them.
How technology has helped older people
Such training can have life-changing effects. This article interviewed people over the age of 64 in Lisbon on how using new technologies improved their lives.
The stories included 74-year old Carlos, who bought a computer after his wife died so he wouldn't feel so lonely. He now enjoys using it to edit and view photos from his new digital camera.
70-year old Ana uses Skype to video chat with her grandchild in Paris who she has never met, saying "they can see me and talk back to me…it's amazing."
Another older person who has fully embraced and benefited from digital technologies is 94 Italian Lea Mina Ralli. Not only does Ralli use a high-tech robot to help her live an independent life, she also writes her own blog 'Nonne Lea' (in Italian).
As European Commission Vice President Neelie Kroes put it:
"None of us is getting any younger. But we all want to know that we will not lose our dignity, respect and independence as we age. The EU is investing in new technology that can support the silver generation – adding not just years to our life, but also life to our years!"

subset: commoncrawl


text: The campaign works with more than 1050 vulnerable schools from Andaman and Nicobar Islands, Assam, Bihar, Gujarat, Jammu and Kashmir, Maharashtra, Puducherry, Rajasthan, Tamil Nadu and West Bengal states/Union Territories of India as well as neighbouring countries like Afghanistan, Bangladesh, Maldives and Myanmar. The Campaign developed various activities based on disaster response and local experience with the school stakeholders. Currently campaign emphasizing its work in vulnerable schools located in urban and coastal areas. The All India Disaster Mitigation Institute (AIDMI) - India-AIDMI has received over 400 enthusiastic requests from organizations and individuals representing 48 countries across the globe, from northern or southern civil society or governments, UN, Red Cross movement, donors, researchers and consultants that are either already engaged or interested in making schools safer.


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Unscented Facial Oil for all skin types, especially sensitive.
Our unscented facial oil moisturiser offers pure organic vitality for those who are sensitive to essential oils and enjoy the natural aromas of unrefined oils. This impressive range of cold-pressed oils is rich with polyphenols, antioxidants, vitamins A, C & E, with high-level fatty acids to help minimise signs of ageing and enhance the appearance of natural healthy vitality and a look of pure radiance.
Camellia seed oil, Pomegranate seed oil, Rosehip seed oil, Perilla seed oil, Argan seed oil, Marula seed oil, Moringa seed oil, Borage seed oil, Passionfruit seed oil, Carrot seed oil, Buriti fruit oil.
Suitable for vegans.
All skin types, especially sensitive.
Apply to cleansed skin and neck. Take care to not apply oil too close to eye opening to avoid eye irritation.
Camellia oleifera (camellia) seed oil; Punica granatum (pomegranate) seed oil; Rosa rubiginosa (rosehip) seed oil; Borago officinalis (borage) extract; Perilla frutescens seed oil; Argania spinosa (argan) kernel oil; Sclerocarya birrea (marula) seed oil; Passiflora edulis (passion fruit) seed oil; Daucus carota sativa (carrot) seed oil; Moringa oleifera seed oil; Vaccinium macrocarpon (cranberry) seed oil; Mauritia flexuosa (buriti) fruit oil; Rosmarinus officinalis (rosemary) leaf extract
NON-TOXIC ingredients FREE OF harsh chemicals and synthetics, sulphates, artificial fragrances or colours, animal products or gluten. No animal testing. Suitable for vegans.
Camellia Seed Oil
Passion Fruit Seed Oil
Rosehip Seed Oil
Vitamin C - Rosehips are very high in vitamin C, which helps preserve a firm and tighter appearance in the skin. Vitamin C is also a powerful antioxidant, protecting from environmental stressors, which cause skin dryness, fine lines, and wrinkles.
Vitamin A - Rosehip seed oil is high in vitamin A, a key age-defying ingredient and powerful antioxidant, it promotes firmer, smoother skin.
Essential fatty acids - Essential fatty acids moisturise and hydrate skin.


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Today, the market for variable speed drives offers a large number of devices which are functionally similar, fulfil all the minimum requirements and are therefore more or less easily interchangeable. Since the applied quality standards are similarly high, differentiation is only possible with application-specific drives or the reduction of cost. An innovative starting point for cost reduction is the integration of additional features into the power module. In the SEMiX 3 Press-Fit series, SEMIKRON offers IGBT modules in half-bridge topology with integrated shunts for current measurement.
Looking at the bill of material of today's variable speed drives in the medium power range, e.g. 75kW to 160kW, it shows that the current sensors, their fastening, supply and interface connection make up a considerable part of the total material costs. In addition to the pure material costs, installation space must also be provided for the sensors. On top, the sensors must be manually assembled and connected, which generates additional costs in the assembly process.
Integrated shunt resistors
This is where the SEMIKRON IGBT module SEMiX 3 Press-Fit Shunt, using integrated shunt resistors for current measurement, has its place. Thus, the use of additional current sensors becomes unnecessary. The SEMiX product family is an IGBT module in half-bridge or chopper topology for 1200V or 1700V and up to 600A. With a height of 17mm, the module is the industry standard for medium to high power applications. Through the use of press-fit contacts for the auxiliary connections the assembly is completely solderless. In conjunction with the SEMiX bridge rectifiers in the same design the system offers maximum performance with optimised system costs. In addition to the significantly lower costs, the current measurement using the integrated shunt resistors also offers considerable advantages in accuracy as well in the bandwidth of the measured values. The shunt resistors consist of a special alloy, which can be used up to an operating temperature of 250°C. Due to the low temperature dependence and high linearity of the shunt resistor, the SEMiX 3 Press-Fit Shunt is ideally suited for demanding control tasks thanks to the very precise feedback signals. Considering the lower component complexity and the simplicity of the components, the SEMiX 3 Press-Fit Shunt also reduces the failure rate compared to conventional inverter systems with standard current transformers. Additionally the shunts clearly surpass the overload capacity inherently limited by current compensated sensors. The intelligent integration of the resistors into the power module does not require any additional space, and the SEMiX 3 PressFit Shunt offers the same performance data as identical modules without integrated measuring resistors.
Integrated signal transmission on driver module
However, the integration of the current measurement also necessitates some challenges: Instead of a galvanically isolated signal from a current transformer, the shunt voltage is now measured at DC-bus potential. Before this can be further processed by a higher-level controller, isolation and digitisation must first take place. This task is carried out by the SKYPER 12 driver in conjunction with a delta-sigma modulator. The SKYPER 12, based on a SEMIKRON developed ASIC, on the one hand takes care of the safe and optimised control in the permitted save operating area (SOA), as well as the evaluation of the DC-bus voltage and the temperature measurement integrated in the module and provides this as a safe galvanically isolated signal to the controller.
SEMIKRON offers an adapter board for the evaluation of SEMiX 3 Press-Fit Shunt systems, which interfaces the SKYPER 12 to the module. By integrating all required supplies and signal and fault management into the ASICs, the number of individual components on the driver can be reduced by 30%, which increases the service life by up to 20%, depending on the load profile. As a result, the SKYPER 12 achieves an MTBF rate of over 8 million hours. The two purely digital ASIC modules are used on both, the primary and the secondary side, and do not use analogue filter modules. As a result, the signal propagation times can be optimised and the time offset of the signals is reduced to below 30ns. The metallic shield of the ASIC housing assures maximum temperature stability and reduces susceptibility to interference.
A serial UART standard interface as well as a differential signal interfaces the driver to the higher-level controller. The IC-based delta-sigma modulator, which is located on the adapter board, converts the voltage signal of the shunt into a digital differential signal at a clock frequency of 20MHz, which emphasises the high accuracy of the current measurement. As a result, there are no deviations in the measured values stemming from converter or component tolerances on the further signal path to the higher-level control. The delta-sigma converter is supplied by the secondary side of the SKYPER 12. Depending on the selected modulator IC the safe separation of the potentials is achieved either capacitively or optically.
By using the package of SEMiX 3 Press-Fit Shunt as well as the optimised SKYPER 12, the development times can be drastically reduced because design loops are avoided and the system development is completed in the shortest possible time.
The press-fit technology also optimises the manufacturing process. Only the driver board has to be pressed onto the module, and thus all current, voltage, and temperature measuring systems are installed. No further boards are required for signal processing, which reduces production costs and improves quality and FIT rate.
Pre-applied phase change material
The final stage of the integration is provided by the pre-applied thermal interface material. Phase change material (PCM) is used which, at room temperature, is solid and thus smudge-free. Compared to viscous thermal pastes, this allows the maximum process reliability during assembly of the modules. The print pattern of the PCM is perfectly matched to the module baseplate and is applied by means of a controlled screen printing process, thus guaranteeing optimum distribution of the thermal conducting material. This results in a 10% lower thermal resistance which, in turn, leads to lower junction temperatures during operation. This means either increased lifetime of the module or increased output current, which in turn increases the power density.
Optimised overall concept through integration
The connection of SEMiX 3 Press-Fit Shunt with SKYPER 12 and pre-applied phase change material offers the maximum integration of components, which results in significant cost savings, space savings as well as reduced development times and increased reliability for the entire system. This makes SEMIKRON a reliable partner for inverter manufacturers, to develop competitive equipment for a demanding market.


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Follow these accounts to stay up to date on industry trends and tips
Inspiration is key to any endeavor, but it is particularly crucial in the world of real estate, where creativity and aspiration are at the crux of every successful project. Real estate professionals at all levels, in all corners of the industry, can benefit from a steady drip of inspiration, and one of the easiest ways to find it is by following other industry pros on social media.
We've rounded up 10 of the most prolific and engaging real estate influencers on social media. If you're looking for a little inspiration on Twitter or Instagram, you should start by following these people.
Amy Bohutinsky
Amy Bohutinsky is the COO of Zillow Group, the massive online real estate database whose subsidiary brands include Trulia, HotPads, StreetEasy and Naked Apartments. Bohutinsky is also a board member with hotel-deal site HotelTonight and legal-services site Avvo.
Desiree Patno
The CEO and founder of the National Association of Women in Real Estate Businesses, Desiree Patno is a must-follow for real estate professionals and anyone in any industry who is interested in the advancement of women in business.
Cody Sperber
The man behind the wildly popular Clever Investor Instagram account, Cody Sperber is a real estate investor and the author of How to Flip Houses With Little or No Money, which Entrepreneur recently named one of the 10 must-read books about the market.
Ryan Serhant
Best known as one of the stars of Bravo's Million Dollar Listing, Ryan Serhant has leveraged his celebrity to create one of the most influential brands in real estate.
J. Massey
Twitter: @cashflowdiary
J. Massey cut his teeth in real estate and remains a full-time investor, but he is best known for his work as a podcaster, career coach, speaker and author of Cash Flow Diary: 10 Steps to Creating Wealth in Any Economy.
Scott McGillivray
A mainstay on the HGTV and DIY networks, Scott McGillivray's growing roster of TV shows tap into the real estate pro's bona fides as both a contractor and real estate investor with a knack for helping homeowners find inexpensive renovation solutions.
Chad Carroll
The executive vice president of Douglas Elliman, a massive East Coast luxury real estate firm, Chad Carroll parlayed his enviable success in real estate sales to a role in Million Dollar Listing Miami and a growing lifestyle brand on social media.
Josh Altman
Josh Altman's real estate dealings with high-profile clients in the Hollywood Hills and Beverly Hills markets earned him a reputation as one of Los Angeles's leading agents, a standing that caught the eye of the producers at Bravo, who enlisted Altman for the LA spinoff of Million Dollar Listing.
Barbara Corcoran
As an investor on ABC's Shark Tank, Barbara Corcoran built a reputation as a compassionate but no-nonsense investor with an eagle eye for potential in all areas of business, but Corcoran's bread and butter has always been real estate.
Fredrik Eklund


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Your Tour at a Glance
We are currently building the itinerary for the tour date you have selected.
Traveler Reviews
ServiceEverything was done well Saw what I did the trip for (Viking Village). Great service by bus driver Pete Sullivan and tour guide Bernadette Walsh.
TourVikings settled here In 1000 AD that is awesome.
ServiceSmall group size. Tour manager and driver very knowledgeable and personable.
TourThe beauty of the country and the friendly people
ServiceIf you have reviewed the comment card you will notice that I have given no excellents. This is because to my way of thinking excellent leaves no room for improvement. However Bernadette Walsh is one of the VERY best tour guides I have had with Collette! If your records have been up dated this was my 8th tour with Collette (not 4 as noted) starting in 2008. I have been fortunate to have well informed tour guides (thanks to Collette). Bernadette showed me her province with enthusiasm, love, pride and knowledge of the people, of geography of Newfoundland. It was a treat to have her as a guide, she is a real gem! Please,I would like you to acknowledge my response
TourNewfoundland is a treasure! Memorable - the history (part of my country"s), the geography. We saw puffins, whales, icebergs, the viking village, the ferry trip Labrador, Terry Fox statue (I remember Terry starting his journey across Canada), Insectarium, Again Please confirm this response
Thank you for traveling with Collette on our Wonders of Newfoundland tour and for taking the time to complete our Feefo survey. We're pleased to hear you had such an enjoyable experience on tour. Your comments will be forwarded to your tour guide's team leader in the Tour Management department so she can receive the commendation she deserves.Collette Support


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Infologica's Key Web Application Services:
"Our experience with Infologica was very positive and extremely professional. At every point we had instant access to communicate with our project manager online who could answer any and all questions and provide immediate fixes. Infologica is a very reliable company capable of foreseeing our development needs. My overall feeling is that we received and excellent marketable product and a long lasting technology partner."
Ecommerce Solutions:


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Price: £58.00
Quantity: 1 available
Book Condition: Very Good
This is the collectable Wesleyan edition from the works of Henry Fielding first published 1988. Book is very bright and clean 339 pages dustwrapper a little dusty on edges, several small spotted marks on front of wrapper and tear bottom right corner 2.5 cms long. Social comment from Henry Fielding written during the period 1749 to 1753 when he was a magistrate. Overall a nice copy SEE IMAGE. DETAILED IMAGES AVAILABLE ON REQUEST.
Title: An Enquiry Into the Causes of the Late Increase of Robbers and Related Writings
Categories: History,
Edition: Collector's Edition
Publisher: Oxford Uk, Clarendon Press: 1988
Binding: Cloth
Book Condition: Very Good
Jacket Condition: Good Plus
Type: Hardcover
Size: 24 Cms X 16 Cms
Item: 1.00 Item
Seller ID: 002546
Keywords: Literature. Collectable Edition. Wesleyan Edition,


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INJURED IN A SLIP AND FALL? You need Lafferty Gallagher & Scott fighting for you
Store owners and other commercial property owners enjoy a lot of protections under Ohio law. They have no duty to protect their customers from dangerous conditions which the customer knew about or should have known about. And even when the customer is not aware of the dangerous condition, the store owner has no duty to protect or warn their customers about a dangerous condition unless the store knew about it or should have known about it.
Slip and fall cases are among some of the most difficult cases to pursue in Ohio because of the protections afforded property occupiers and owners under the law. But, when a store creates a dangerous condition, such as mopping a floor without placing a wet floor warning sign, they may be responsible for any injuries caused by the dangerous condition.
Some of the most common examples of dangerous conditions that a business owner/occupier is responsible for include:
- Mopped floors without warning signs
- Untreated spills by customers that were discovered or should have been discovered by the store employees
- Poorly designed/located displays
- Uneven flooring
- Unnatural accumulations of snow and/or ice
- Insufficient or non-existent lighting
- Unsecured or improperly secured overhead signs and displays
- Unsafe means of entering/exiting
The information contained in this blog post is general information, and should not be treated as legal advice. No attorney/client relationship exists between the reader and Lafferty, Gallagher & Scott, LLC without a signed Attorney Contract Agreement of Representation. Each case is unique and past results should not be treated as a guarantee of the results in your case.


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A superb, and unique, pink-tinged gin. Infused with rose petals and cucumber as well as the normal botanicals, this is a must for all gin-lovers.
Hendrick's makes a fantastically refreshing Gin & Tonic: serve in a tall glass with plenty of ice and garnish with thinly-sliced cucumber!
If you have any questions about this product, let us know.


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1 Items
- clearance
Paslode IM360/IM90i 75x3.1MM Ring GALV Plus PK2500 142030
£67.55Ex VAT£81.06 Inc VAT
- Available in branch
- Click & Collect
- Next Day Courier
More information about Nailers
The many advantages of air tools make them ideal power tools to have around. Air tools, also sometimes called 'pneumatic tools', are professional trade power tools that are light, powerful and easy to use. From popular trade brands Paslode and Tacwise, nailers offer a variety of solutions for hard to reach places and are especially useful tools for working with wood.
Benefitting from a quick-charge, long-life battery, the Paslode angled gas finishing nailer makes any job quick and easy with improved line of sight, and improved weight and balance.
You can nail up to 50mm and staple up to 45mm with the 240v Tacwise Duo 50 Nailer/Stapler. A new generation product and world first, this handy nailer is strong and versatile, making it the perfect tool for any tradesmen.
With our selection of nailer types, you'll find the right trade brand product to help you complete the job.


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Home > Railroads > Former Railroads > New York Central Hudson Division - Troy to Oscawana > Camelot
There isn't even a place called Camelot anymore, but there is a Camelot Road. The road and an old right of way head toward the tracks, but there is now a large quarry between the road and railroad so it's hard to guess exactly where Camelot used to lie. From the train however I did see this paved section in that general area. I don't know if it is actually related to the old station though.
Welcome Page | Railroads | Former Railroads | Site Map
If you have any questions / comments / corrections for this website or find a broken link, please e-mail me.
Copyright 2011-2016 by Robert Mortell


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SharePoint Framework Special Interest Group (SIG) bi-weekly community call recording from April 11th is now available from the SharePoint Development YouTube channel at http://aka.ms/spdev-videos.
Topics covered on April 11th, 2019
- SharePoint Framework update from Microsoft Engineering (3:45)
- PnP JS Core library update (9:29)
- Office 365 CLI update (13:04)
- Reusable SPFx controls update (14:18)
- PnP SPFx Yeoman extension – (16:25)
- Demo – Hugo Bernier – React Comparer web part with a custom file picker control (18:42)
- Demo – Joel Rodrigues (CPS) – React My Teams web part with Microsoft Graph usage (34:53)
- Demo – Ejaz Hussain (Content and Code) – React image gallery with dynamic taxonomy search (50:22)
Additional resources around the covered topics and links from the slides.
- The presentation used in the community call
- Hugo's demo solution in GitHub | Blog post
- Joel's demo solution in GithHub
- Ejaz's demo solution in GithHub | Blog post
- Latest documentation on SharePoint Framework
- Found an issue with SharePoint Dev? – please let us know at http://aka.ms/spdev-issues.
- @pnp scoped libraries
- Reusable web part property controls
- Reusable react controls for SharePoint Framework solutions
- Reusable controls webcast
- Office 365 CLI
- PnP SPFx Yeoman Generator – Extends the out-of-the-box experience with open-source community capabilities
- SharePoint Dev UserVoice – for new feature requests
Other mentioned topics
Next Meeting is April 25th, 2019, see you then!
PnP SharePoint Framework Special Interest Group bi-weekly calls are targeted for anyone who is interested in the JavaScript-based development towards SharePoint Online and also on-premises. SIG calls are used for following objectives.
- SharePoint Framework engineering update from Microsoft
- Talk about PnP JavaScript Core libraries
- Office 365 CLI Updates
- SPFx reusable controls
- PnP SPFx Yeoman generator
- Possible engineering asks for the field – input, feedback, and suggestions
- Cover any open questions on the client side development
- Demonstrate SharePoint Framework in practice – also community demos are more than welcome (let us know, if you're interested)
You can download recurrent invite from https://aka.ms/spdev-spfx-call. Welcome and join the discussion!
"Sharing is caring"
SharePoint Team, Microsoft – 12th of April 2019


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How funny that during my 60ish day running streak, I would have been out in this weather. Now, with the streak over, I easily decided, "nah, I'll run long another day, even if I just need to make it a two-a-day during the week." Why?
- Because 6 months ago I would not have known that I could, if needed or called upon, run at all in that weather.
- Because I was not mentally tough about my running.
- Because I lacked confidence in my ability to imitate Nike and "just do it".
And this was the purpose, the goal, of the running streak. I didn't have a number of days or number of miles to tell me when to end this unintentional streak. At some point, I knew it was important to continue because it was making me a physically and mentally stronger runner. And at the end of day 63, I was able to look inside myself and decide to wave the giant banner of "Mission Accomplished".
So now I know I can do it. And the biggest piece is I DON'T HAVE TO REPROVE IT TO MYSELF. So when I thought I could just sleep in and stay inside and keep warm and not completely wreck my running, oh yeah it was an easy decision.
Congrats to all who went out and ran in this weather today. And if you decided not to run in it, and are not sure you could have if you needed to, think about that and maybe one day you'll go out in it anyway because it pays bigger mental dividends than physical you know realize. And if you decided not to run in it for the reasons I also felt, I salute you too! No one is better or worse for choosing to run in this weather, we're all just in different places in our running. :-)
Happy Running!


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10 May 2006
In 190 BC, the Romans under Lucius Cornelius Scipio defeated the Seleucids at the Battle of Magnesia, placing Greece under Roman control and no doubt contributing to the Empire's future heartburn.
Meanwhile, on the other side of the calendar, Mark A. Rayner, with the assistance of General Kang, presents Carnival of the Vanities #190, a week's worth of bloggage in a single handy compendium.Posted at 11:06 AM to Blogorrhea
In 190 BC, the Romans under Lucius Cornelius Scipio defeated the Seleucids at the Battle of Magnesia...
After which they celebrated with the local milk.
The morning after was ... unpleasant.Posted by: McGehee at 12:17 PM on 10 May 2006
Nothing like the heartburn they gave Hellenes, by grafting the Roman descriptor "Greeks" onto them and their land/culture -- a mis-identifier that persists to this day in most of the world west of Asia Minor. (A Persian moniker took care of a big chunk east of that.)
It was karmic, as the Greeks did the same thing to Egypt. To the victors go the naming rights.Posted by: CT at 10:14 AM on 12 May 2006
That's what they say in Texas. (And it makes you wonder how France managed to stay France all those centuries.)
If it makes you feel any better, in modern Greek, it didn't: The name still translates literally to Gaul. (Says more about the Greeks clinging to old labels than anything else, actually.)Posted by: CT at 10:49 AM on 15 May 2006


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We examined individual differences in leadership behaviour in the Ghanaian business sector. Specifically, sex differences as well as level of education on leadership behaviour were examined. Cross-sectional survey design was used to study 95 participants conveniently sampled from selected organizations within the Greater Accra Metropolis. Questionnaire was used to collect data from a cross-section of people in the organization. Test of normality and reliability testing were conducted as part of the preliminary analysis. Multivariate test was used to test the hypotheses in the study. The result showed that females showed significantly people-oriented leadership behaviour than their male counterparts. However, level of education did not significantly influence the leadership behaviour of participants. Implications and limitations of the study are provided.
Full Text:PDF
Bem, S. L., (1974). The Measurement of Psychological Androgyny.Journal of Consulting and Clinical Psychology, 42: 155-162
Deaux, K & Lewis, L.L. (1983) Components of Gender Stereotypes.Psychological Documents, 13(2): 25-50.
Donnell, S.M. & Hall, J. (1980). Men and women as managers: a significant case of no significant difference", Organizational Dynamics, Spring, pp. 60-77.
Eagly, A. H. (1987).Sex Differences in Social Behaviour: A Social Role Interpretation, Hillsdale, NJ. Erlbaum.
Helgesen, S. (1990).The Female Advantage: Women's Ways of Leadership, Doubleday, New York, NY.
Korabik, K. (1990). Androgyny and leadership style.Journal of Business Ethics, Vol. 9, pp. 283-92.
Powell, G.N. (1988). Women and Men in Management, Sage Publications, Newbury Park, CA.
Rosner, J. B. (1990). Ways Women Lead. Harvard Business Review, November-December: 119-125.
Ruble, T. L. (1983). Sex Stereotypes: Issues of Change in the 1970s. Sex Roles, 9: 397-402.
Spencer, J.T & Helmreich, R.L. (1978).Masculinity and Feminity: Their Psychological Dimensions, Correlates and Antecedents. Austin, Tex: University of Texas Press.
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DOI: http://dx.doi.org/10.18533/ijbsr.v4i4.461
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Transient Elastography (TE) is a Useful Tool for Assessing the Response of Liver Iron Chelation in Sickle Cell Disease Patients
Sophia Delicou1, Konstantinos Maragkos1, Maria Tambaki2, Dimitrios Kountouras2 and John Koskinas2.
1 Thalassemia and Sickle Cell Department, Hippocratio General Hospital Athens.
2 Second Academic Department of Medicine, School of Medicine, National and Kapodistrian University of Athens, Hippokratio General Hospital Athens.
Received: April 24, 2018
Accepted: August 6, 2018
Mediterr J Hematol Infect Dis 2018, 10(1): e2018049 DOI 10.4084/MJHID.2018.049
This article is available on PDF format at:
| This is an Open Access article distributed
under the terms of the Creative Commons Attribution License
(https://creativecommons.org/licenses/by-nc/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
cell disease patients often need regular blood transfusions to improve
both the quality of life and survival from the veno-occlusive
complications of the disease. Deferasirox, a convenient long acting
oral agent, has recently been introduced in clinical practice with
promising efficacy.
A more convenient oral iron chelator, deferasirox, has recently become available showing promising efficacy. Many studies have shown that deferasirox has an acceptable profile of safety and tolerability in thalassemic patients.[2,4,5]
Liver iron concentration has been regarded as the reference standard for estimating body iron load in thalassemic patients and has been shown to predict total body iron stores accurately. In sickle cell anemia, the liver is one of the target organs of the disease itself, except the transfusional iron overload. The term "sickle cell hepatopathy" has sometimes been used to reflect the overlapping acute and chronic causes of liver dysfunction in these patients. Studies in patients that have been hospitalized due to an acute vasoocclusive crisis have estimated the frequency of liver involvement ranging from 10% to 39% and an autopsy study of sickle cell patients has revealed the presence of hepatic infarction in 34% of patients.[6,7]
Prior studies have based on data from hereditary hemochromatosis and thalassemia major showing that elevated hepatic iron content determined by liver biopsy and imaging techniques over 7 mg/g liver dry weight is a risk factor for hepatic fibrosis. Therefore this value has been used as a guide to start chelation therapy.[4,5,7,8]
Transient elastography and has been extensively validated in chronic liver diseases and is currently used for detection and staging of liver fibrosis.
In the last few years, liver stiffness measurement (LSM) by transient elastography (TE) has been shown to be closely related to the degree of hepatic fibrosis assessed by biopsy in thalassemic patients.[9,10]
However, hepatic involvement has been shown to affect liver stiffness in patients with sickle cell disease during acute vaso-occlusive crisis measured with transient elastography.[11]
The study aimed to evaluate the role of elastography (Liver Stiffness Measurement, LSM, kPascals, FibroScan, Echosens, Paris, France) in patients with SCD and explore possible correlations with clinical and laboratory characteristics, mainly those associated with iron overload.
Materials and Methods
Fifteen patients with SCD who are followed-up in the Thalassemia and Sickle Cell Unit of Hippokrateion General Hospital in Athens, Greece were enrolled in the study. All patients completed the study.
Five patients had HbS/HbS, and thirteen had HbS/beta-thal; their median age was 45,8 years (range: 19–75 years). Seven patients were males and eight females.
Patients received regular blood transfusions or had sporadically transfused with at least 20 units of packed red blood cells during the last five years. Exchange or simple transfusions were allowed. Transfused red cells were negative for hemoglobin S, phenotypically matched and depleted of leukocytes and were delivered in a volume of approximately 10 to 15 ml per kilogram of packed cells per transfusion. The goal of the transfusion protocol for all patients was to maintain their hemoglobin S (HbS) percentage at or below 50% and the pre-hemoglobin and post-hemoglobin greater than 9 g/dL and less than 12 g/dL, respectively.
The initial dose of DFX was calculated based on the patient's body weight (10-40 mg/kg/day). The 20-mg/kg dose was considered appropriate for patients requiring reduction of a moderate iron burden, and a higher dose of 30-40 mg/kg was felt to be appropriate for patients with high iron burdens requiring major reduction of excess iron. Lower doses of 10-mg/kg were selected for maintenance use in patients with lower LIC values. DFX was taken daily every morning 30 minutes before breakfast, dispersed in a glass of water. Prior chelation therapy was permitted but was not mandatory. The serum ferritin level for entry into the study was ≥500 μg/l.
Patients eligible for entry into the study had performed MRI using a multi-gradient recalled echo (MGRE) sequence which allowed the determination of liver T2*, a relaxation time constant sensitive to the presence of liver iron, inversely proportional to liver LIC (Liver Iron Concentration).
They also had performed Liver stiffness measurement (LSM) using transient elastography (Fibroscan). A pulse-echo ultrasound acquisition is used to follow the propagation of the shear wave and to measure its velocity, which is directly related to tissue stiffness and the severity of liver fibrosis.
The patients were evaluated at the enrollment and at the end of the study. Laboratory assessments were performed at least monthly and included complete blood counts with differential counts; Alanine Transaminase [ALT], Aspartate Transaminase [AST] Lactate Dehydrogenase [LDH] and ferritin. The concentrations of high sensitive C-reactive protein were also evaluated.
Urinary testing performed on random collections included determination of creatinine, total protein, and albumin. Physical examinations, electrocardiograms (ECGs), audiometry and ophthalmological tests were performed at baseline. The study duration was 52 weeks (12 months).
Patients were excluded if they had a serum creatinine above the upper limit of normal if they had significant proteinuria or if they had active or chronic hepatitis B or C. Other exclusion criteria were second and third atrioventricular block, QT interval prolongation, or therapy with digoxin or similar medications. Treatment with β-blockers or angiotensin-converting enzyme inhibitors was permitted. Patients with chelation therapy-associated ocular toxicity were excluded. No one patient had clinical or imaging findings suggesting the presence of liver cirrhosis at baseline or at the end of the study.
Statistical analysis. Data are reported as mean ± SD. Comparisons among groups were made using one-way analysis of variation (ANOVA) analyses, where P < 0·05 was considered statistically significant.
Post hoc tests were Student's t-test for paired variables and Wilcoxon nonparametric test. All P values are two-sided and considered significant with P ≤ 0.05. The Pearson's correlation coefficient r with p-value is used to measure the strength of a linear association between Ferritin, LIC biochemistry and Fibroscan and hs-CRP variables. Statistical analyses were performed using MedCalc for Windows, version 15.0 (MedCalc Software, Ostend, Belgium).
|Table 1. Summary of the parameters and evaluated values at baseline and at the end of the study.
After 12 months (52 weeks) of deferasirox therapy, a significant improvement in LIC from 7.86 to 5.62 mg range:3.1-20.1 mg Fe/g dry weight p=0.043 was found (Figure A1), followed by significant improvement of serum ferritin mean from 2373.33 to 1532 ng/ml range: 210-6300, p=0.002 (Figure A2).
The above findings were followed by an improvement in liver stiffness from 9.7 kPa to 6.7 kPa range:5.1-10.1, p=0.001 (Figure A3). A significant improvement in AST, ALT, and LDH at 52 weeks was also noted. There was no significant difference in hs-CRP and serum creatinine from baseline to end of the study.
A significant correlation (r1: pre-treatment, r2: after treatment) between ferritin levels and LIC (r1=0.862 and r2=0.9298) and between ferritin and LSM (r1=0.6905 r2=0.7936) was found respectively. Furthermore, the correlation between LIC and LSM was statistically significant at baseline(r1=0.6344) and at the end of the study (r2=0.6075). No correlations were found between the other parameters (Table 2).
|Table 2. Correlations between all parameters.
Safety and tolerability. During the study 39 Adverse Events were reported. The most common AEs reported were abdominal pain 41% (7/39), diarrhea 38,5% (15/39), nausea 10,3% (4/39), and nasopharyngitis 7,7% (3/39). Nausea and abdominal pain were reported on the same day in those patients. Sickle cell painful crisis 2,6% (1/39) was managed at home. No serious AEs were experienced during the study.
Serum creatinine levels were mostly stable during the study. Calculated creatinine clearance with Cockcroft and Gault formula remained stable during deferasirox treatment. Eight patients who received concomitant hydroxycarbamide during the study remained relatively stable in the liver and renal function.
The severity and mechanism of body iron overload in SCD is completely different compared to the iron overload that occurs in thalassemia major. Transfusion-acquired iron overload in the heart is rare in sickle cell disease, probably because iron released by transfusion and haemolysis is efficiently handled by the effective erythropoiesis of sickle cell disease, but not as well by the ineffective erythropoiesis in thalassaemia.[2,14,15]
Sickle cell disease is also associated with a chronic inflammatory state and increased haemolytic status related to vasocclusive crisis.
Consequently, guidelines such as those in the UK currently recommend initiating iron chelation therapy in patients with SCD once LIC increases to ‡7 mg Fe/g dry weight if serum ferritin steady-state levels are >1000 μg/l, or at least 20 top-up transfusions.[16]
The gold standard for assessing liver iron stores is the hepatic iron content determined by liver biopsy, but this technique is limited because it is invasive and carries a risk of complications. Noninvasive methods including lood tests and imaging techniques have been evaluated and considered in greater detail.[17,18,19]
Studies of liver biopsies in patients with SCD have linked transfusional iron load with LIC, fibrosis, and cirrhosis. If transfusion is given without chelation, portal fibrosis can develop as early as two years after transfusion. With sequential biopsies, increased fibrosis was found in 1/3 of patients with LIC values > 9 mg/g dry weight and in direct proportion to the LIC.[20,16]
TE is an ultrasound-based tool for measuring liver stiffness as a surrogate of fibrosis that is widely used due to its high accuracy for the diagnosis of fibrosis stage.[21,22]
Liver stiffness also correlates with cirrhosis complications including variceal hemorrhage, ascites, and hepatocellular carcinoma (HCC). The iron effect in the pathogenesis of fibrosis due to increased oxidative stress and other pathological modes of action of HCV, ethanol, and steatosis, lead to mitochondrial dysfunction and hepatocyte apoptosis.[23] Hepatocellular carcinoma following liver cirrhosis as a complication of chronic hepatitis C and iron overload has been reported in thalassemia patients.[24,25] Cirrhosis, is the strongest and the most common known risk factor for HCC, is frequently found in thalassaemia patients as it has been described from the Italian Registry.[24,25,26,27]
In Drasar's research paper (2016) have shown that transfusion and markers of iron overload were weakly but significantly correlated with T.E and enhanced liver fibrosis score (ELF) using standard markers of liver function.[21]
In our study LIC, LSM and serum ferritin level were significantly reduced after 12 months of deferasirox treatment indicating that over 12 months, deferasirox significantly reduced liver iron burden in these iron-overloaded patients with SCD.
Also, ALT, AST, and LDH levels significantly decreased after 12 months of therapy suggestive an improvement of liver inflammation. Furthermore, ferritin and LIC significantly correlate with hepatic stiffness before and after deferasirox administration suggesting that reduction of iron in the liver leads to stiffness improvement. Our results are in agreement with Deugnier (2011) and Adams (2011) that deferasirox can lead to regression of fibrosis, improving liver stiffness and correlating with iron removed.[28,29]
Adequate chelation therapy is mandatory to prevent liver disease progression in sickle cell disease patients.
Additionally both AST and ALT showed significant improvement over the course of the study but showed no correlation with liver stiffness. Although transaminases are markers of inflammatory liver reaction and is well established that high levels influence the elastographic findings, the absence of correlation in our study is due to mildly increased levels of transaminases at the onset of the study.
Hs-CRP remained stable from the beginning to the end of the study, and show no correlation with ferritin or other parameters.
In addition, studies of deferasirox in patients with thalassemia provided evidence of significant reduction in hepatic fibrosis irrespective of hepatic iron concentration or HCV prevalence. Our results clearly demonstrate that the observed improved of hepatic stiffness is mainly associated with the reduction of hepatic iron and not by the improvement of inflammatory status.[30,31]
Patients with the sickle cell disease are at risk for significant hepatic complications, and better definitions and markers could be utilized to understand the pathophysiology of hepatic involvement. Taken together, these results suggest that TE is a useful and less expensive than the MRI tool to identify the stage of stiffness/fibrosis in patients with SCD at steady state and to monitor the efficacy of chelation therapy.
ConclusionsIn this study, LSM shows a strong relationship with LIC. Both baseline LSM and LIC changed and correlated with ferritin at the end of the study. The efficacy of deferasirox in hepatic iron removal in patients with sickle cell disease also improves the inflammatory response. Transient Elastography (TE) is a useful tool for assessing the response of liver iron chelation, it is much more widely accessible, and it is also useful for more intensive surveillance of liver stiffness. TE is a relatively low cost easy to perform the test, with high accuracy evaluating liver stiffness in this patients reflecting both fibrosis and hemosiderosis on the top of surrogates markers of iron overload.
- Chaturvedi Shruti, and Michael R. DeBaun. Evolution
of sickle cell disease from a life‐threatening disease of children to a
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John and Maciej Garbowski. Consequences and management of iron
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Gaetano et al. "Chelation treatment in sickle‐cell‐anaemia: much ado
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Lina B. et al. Liver biopsy results in patients with sickle cell
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- Marsella Maria and Caterina Borgna-Pignatti. Transfusional iron overload and iron chelation therapy in thalassemia major and sickle cell disease. Hematology/Oncology Clinics 28.4 (2014): 703-727.
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Ice-bound scientists hit funding and climate questions on return
The scientists stuck on an ice-bound Russian ship in the Antarctic finally arrived back on dry land in Tasmania amid criticism about the resources needed to rescue them and derision from climate change sceptics.
LEIGH SALES, PRESENTER: It was the international rescue deep in the frozen wilderness that grabbed headlines across the world. Today the team of scientists plucked from an ice-bound Russian ship in the Antarctic finally arrived back on dry land in Tasmania. The expedition's drawn criticism for diverting scarce resources for a rescue effort involving four nations and it's also attracted derision from climate change sceptics who gleefully point to the masses of sea ice that trapped the ship. In a moment we'll hear from the expedition leader, Professor Chris Turney, but first, this report from Matt Peacock.
MATT PEACOCK, REPORTER: The Australian icebreaker and in this case rescue ship Aurora Australis arriving in Hobart in this morning. Onboard, the 52 scientists and paying passengers of the privately-funded Australasian Antarctic Expedition, whose dramatic rescue from their ice-bound Russian charter vessel made headlines around the world.
KERRY TOZER: It was absolutely spectacular. You imagine the Antarctic to just be clean and white, but you don't imagine the immensity of it, the enormity of it, the pristineness of it, the amazing wildlife that you get to see.
MATT PEACOCK: Kerry Tozer was one of the Antarctic tourists trapped on the Russian ship for 10 days before their rescue.
KERRY TOZER: The ship actually tilted and listed I think up to about five degrees at one point, just sort of rocked over sideways and everyone's sitting in the dining room - "Ooooohhh, hang on a minute." And yeah, so, there were changes. It was very dynamic. So, yeah, we were a little bit concerned, but never really felt that we were in immediate danger.
MATT PEACOCK: The ship's captain issued a distress call mobilising icebreakers from China, France, the US and Australia to assist.
The passengers were eventually lifted by helicopter to Aurora Australis and in the process the Chinese ship also became stuck in ice.
The delay caused by the rescue's already compromised a major research program underway at Casey Station, according to Antarctic Division director Tony Fleming.
TONY FLEMING, DIRECTOR, AUSTRALIAN ANTARCTIC DIVISION: It will be harmed a little bit, but we always try to recover the projects. There are many reasons for delays in Antarctica. We work with the environment and the environment is very harsh.
MATT PEACOCK: It's this same harsh environment that Sir Douglas Mawson, whose expedition inspired this one faced a hundred years ago.
(male voiceover): "The winds at Commonwealth Bay were the strongest ever recorded on Earth, with gusts of 300 kilometres per hour and more."
MATT PEACOCK: Back on land, today's expedition leaders faced questions about why exactly the ship became trapped, causing a rescue effort that could cost up to $2.5 million.
CHRIS TURNEY, EXPEDITION LEADER: The bottom line was we got caught by a massive breakout of ice.
JOURNALIST: There was an urgency though, was there, from the skipper about getting you back onboard in order to attempt to get out as the ice was closing up?
CHRIS TURNEY: Well, that's - there was calls, that's right, but when we were pulling back out, we were hoping to get out, but then, no, and (inaudible).
MATT PEACOCK: And, if Antarctic ice is really melting faster because of climate change, why then was there more sea ice in the bay where the ship became stuck?
TONY FLEMING: A huge iceberg has grounded in Commonwealth Bay region and the Mertz Glacier Tongue has been knocked off by that iceberg and that led to a buildup of sea ice over many years, so there were specific conditions in the Commonwealth Bay region that aren't related to climate change.
MATT PEACOCK: These expedition photographs taken for the first time of invertebrate life under the ice have strengthened fears that up to a third of this biodiversity is threatened by a climate change tipping point.
EMMA JOHNSTON, EARTH AND ENVIRONMENTAL SCIENCES, UNSW: We have these special communities underneath the sea ice that really don't exist elsewhere. They are bizarre. I've dived in them under the ice. It's like diving into the deep sea. You have sponges that are as tall as me, sea squirts and anemones out this large. I mean, absolutely fantastic and I've never seen it anywhere else and you're shallow, five to 10 metres worth of water.
MATT PEACOCK: When the sea ice melts earlier, these species are being squeezed out by beds of algae like these, filmed further north.
EMMA JOHNSTON: These communities can only exist because the sea ice is actually dropping the amount of light hitting the sea floor, which means they don't get outcompeted by algae. So what we're talking about is the loss of these filter feeding communities, these invertebrate communities that exist, as far as we know, nowhere else.
TONY FLEMING: The knowledge we gain out of Antarctica is incredibly valuable for understanding global systems, atmospheric systems, oceanic systems, and this incident has focused people's minds on Antarctic research.
LEIGH SALES: Matt Peacock reporting.
Author Matt Peacock


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U.S. initial public offerings are set to raise the most in six months in November as Delphi Automotive Plc and Angie's List Inc. take advantage of the biggest rebound in the Standard & Poor's 500 Index in 20 years.
IPOs may raise as much as $3.6 billion, the most since May, when companies sold $6.2 billion in stock, according to data compiled by Bloomberg. At least seven offerings have already been completed this month, with 10 more scheduled, surpassing the total of the three previous months, the data show.
The share sales are trimming the biggest IPO backlog in at least a decade after the S&P 500 rallied 11 percent in October, snapping five months of losses.
Angie's List and Delphi shareholder John Paulson are attempting to follow Groupon Inc.'s Nov. 3 share sale in what could be the busiest week for U.S. IPOs in almost a year. Groupon's stock has gained 20 percent since going public, while more than 60 percent of companies that completed U.S. sales this year are trading below their initial offer price.
"The market strength we saw in October has acted as an accelerant for the IPO market," said Lawrence Creatura, a Rochester, N.Y.-based fund manager at Federated Investors Inc., which oversees $350 billion. "Firms are moving quickly to take advantage of the window that's open this month."
Angie's List, the consumer-review website, is seeking to raise as much as $114 million and will use net proceeds for advertising after marketing costs almost doubled during the first nine months of this year. The Indianapolis-based company is offering 8.8 million shares for $11 to $13 apiece Wednesday, according to regulatory filings and data compiled by Bloomberg, and will start trading the next day. The midpoint values the company at $667 million, or about 8.5 times sales in the year through September. Groupon trades at about 12 times sales.
Cheryl Reed, a spokeswoman for Angie's List, didn't respond to requests for comment.
Delphi, the former parts unit of General Motors Co., is planning a $578 million IPO Wednesday, selling 24 million shares for $22 to $24 each. More than 80 percent of the shares in that offering are being sold by hedge fund Paulson & Co., which is facing withdrawal orders from clients totaling about $2.4 billion. The midpoint of the range would value Delphi at a discount to rival Visteon Corp.
Delphi received orders for all the shares being sold in the IPO, two people with knowledge of the matter said Tuesday.
Lindsey Williams, a spokesman for Troy, Mich.-based Delphi, declined to comment.
The U.S. economy has shown signs of improving since August, when equity markets fell to the lowest level in more than a year and stock volatility surged to the highest since 2009. U.S. gross domestic product grew 2.5 percent last quarter, the fastest pace in a year, and unemployment in October fell to the lowest level in seven months.
The S&P 500 has held on to its gains from last month and is little changed for November. While stock-market swings have stabilized since the beginning of October, the measure of volatility known as the VIX is still about 73 percent above its average level during the first six months of this year.
"There are some positive signs, but we'll continue to see some choppiness," said Herb Engert, Ernst & Young LLP's strategic growth markets leader for the Americas, who advises companies on offerings and mergers and acquisitions. "Companies will continue to look for opportunities as they present themselves."
Caesars Entertainment Corp., the hotel and casino operator taken over by buyout firms TPG Capital and Apollo Global Management LLC in 2008, revived plans for an initial public offering Tuesday after postponing the sale last year.
More companies are planning to seek U.S. listings before the end of the year. Zynga Inc., the maker of online games for Facebook, plans its offering after the U.S. Thanksgiving holiday on Nov. 24, people with knowledge of the situation said this month. The San Francisco-based company filed in July to raise as much as $1 billion in an IPO. Party City Holdings Inc., which filed for a $350 million initial share sale in April, also may complete the IPO by the end of the year, people familiar with the matter said in October.
"I'm encouraged by what I see between now and Thanksgiving," said Robert McCooey, senior vice president of new listings and capital markets at Nasdaq OMX. "If the markets are receptive to the IPOs that are on the road now, you could see a very robust timeframe for IPOs in the two weeks after Thanksgiving before Christmas."


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An artistic pioneer has created "Paris Hilton Autopsy," a rendering of the dead body of the white-sunglasses-wearing, insect woman — complete with exposed innards for visitors to play with! (and Tinkerbell… or is it some other dog now?) Who's up for a field trip to New York to check it out?
*Edited to add: This sculpture is intended to serve as a deterrent against drunk driving. Hmmm.


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Happy March Break everyone! See you back in the 20th!
posted in: Home Page News | 0
Friendly reminder that March 10, 2017 is a PA day for students and kicks off the March Break! See you back March 20.
So proud of our students for recognizing the importance of spreading #kindness and stopping #bullying. Way to go Irwin!bullying. Irwin rocks!
Get Ready for Kindergarten… The District Municipality of Muskoka is extending an invitation to children (and their families) who are eligible for Kindergarten in September (must be age 4 by Dec 31, 2017) Check it out and please pass the … Read More
Check out our latest Newsletter… Eagle News March 2017


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Legal questions and challenges are common in the life cycle of any business. Disputes over contracts or ownership issues can easily arise. As a business finds success and grows, it is necessary to hire more staff and address employment contracts, policies and procedures, management training, and other hiring and termination issues. A former employee who learned the company's trade secrets may take a contact list and try to steal clients for a new venture. In any of these scenarios, it is crucial to obtain sound legal advice.
Duggan Law Corporation has the skill and expertise to guide Northern California business owners in Sacramento County and the surrounding counties through complex legal issues. We provide high-quality legal representation with the personalized service of a small firm. Our clients can count on working with the same team throughout their representation.
Sophisticated Business Litigation Representation
The firm provides legal guidance and counsel to Sacramento-area businesses on civil business litigation matters, including:
- Breach of contract
- Disputes between partners or shareholders that can arise over time with changes in ownership or succession issues
- Unfair business practices and trade secret litigation that often involve the fine line between lawful and unlawful competition
With a wide range of experience, we are able to assist our business and employment law clients with all of their legal issues. We listen carefully to each client's needs so we can tailor an efficient and cost-effective strategy to obtain a stated goal.
Get Answers From An Experienced Business Law Attorney
Contact us to schedule an appointment by calling us at 916-550-5309 or sending us an email. Our lawyers have the experience and creativity to find a timely resolution to legal issues that occur in the course of running a company.


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My only dilemna now is what to blog about on a regular basis. Well, for starters, one of my Etsy teams, Kansas Etsy Team, has started doing giveaways on our blog. Starting today and through March 13, I am the featured vendor and am giving away this beadwoven bracelet.
For a chance to win, please visit http://www.kansasetsyteam.blogspot.com and follow the entry instructions.


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Former baptist pastor, and current political grifter, Mike Huckabee, recently trotted out that hoary old canard about God getting kicked out of schools and people, and children, getting shot because of it. Huckabee takes the view that public displays of piety impress the Lord God. God pats people--and whole nations!--on the head for their sanctimonious posturing.
This would go somewhat against the words of Jesus, who regularly took a dim view of public pieties. He remarked how the scribes, the poseurs of the day, liked to affect long prayers in public "for the sake of appearance" (Mk 12:40), and he didn't think much of it.
In the Sermon on the Mount, Jesus' most important speech in Matthew's gospel, he says, "Beware of practising your piety before others in order to be seen by them; for then you have no reward from your Father in heaven" (Mt 6:1). He went on at some length:
5 'And whenever you pray, do not be like the hypocrites; for they love to stand and pray in the synagogues and at the street corners, so that they may be seen by others. Truly I tell you, they have received their reward.6But whenever you pray, go into your room and shut the door and pray to your Father who is in secret; and your Father who sees in secret will reward you.
Similarly, the prophet Amos had some choice words for people who liked to affect religiosity. He didn't level his words at public display, however. He went right after the people in church! Amos 5:
21 I hate, I despise your festivals,
and I take no delight in your solemn assemblies.
22 Even though you offer me your burnt-offerings and grain-offerings,
I will not accept them
Worship without justice is not supported anywhere in the scriptures. You want to impress the Lord God? Then, said Amos: "Let justice roll down like waters, and righteousness like an ever-flowing stream" (Am 5:24).
"We have systematically removed God from our schools," Huckabee says. Really? Any god who lets himself get pushed around so easily can't be much of a god, and any god who withdraws from the scene to make a culture war point isn't worth worshiping. Mike Huckabee's is a shallow and magical religion with a petulant and little god.


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ShaunOTEast posted a topic in ArchivesHello AJSA! This is my request and introduction to Battlefield 2: Project Reality! Project Reality is a realism total conversion modification for DICE's award winning Battlefield 2 based on the Refractor 2 Engine. The mod focuses on realistic combined arms warfare and teamwork within a modern or unconventional fighting force such as the Canadian Forces or Hamas! Project Reality v1.0 currently includes 40 maps, 13 unique conventional and unconventional factions, and countless amount of weapons and vehicles (I can't even remember/count). The game has Singleplayer 'Co-op' Mode, Multiplayer 'Co-op' and Competitive Multiplayer and is consistently updated by the devs (though, the 'R-DEVs' have a reputation of slow and steady progress). Anyhow, here are the Pros and Cons: Pros Extremely team oriented gameplay, perfect for the AJSA! Lots of replayablity through the many different assets and ways you can approach the objective and enemies. 100 man servers Extremely helpful and friendly players (due to small playerbase), and I'm one of them! Massive maps of up to 4x4 km combined arms maps Minimods and consistent updates! (Vietnam! Falklands! World War 2!) Mumble integration that adds local real time in-game chat, squad chat, inter-squad chat, squad-commander chat, and more. Community organized events by the various clans within Project Reality (Scenario Sundays, One Life Events, Forgotten Honour Tournaments) Community Modding and Factions! (Syrian Uprising, Private Security Contractors, etc) Cons Good amount of bugs and glitches Server stability is not too fantastic to say the least. Considerably large learning curve (good for some I suppose) Aging graphics (BF2 was released in 2005!) Lack of ingame clan support (tags allowed, however) No stat tracking outside of matches (only in games!!!) Slightly slow gameplay. Low player population during weekdays (2-3 servers populated) Videos! PR 1.0 Trailer! Montage! Pure, Raw, and Unadulterated Gameplay! (Oldied but a Goodied) That's all for now, and even if the AJSA isn't completely interested, feel free to check the mod out at realitymod.com Cheers, ShaunOTEast EDIT: Project Reality thread created in FPS Central by Teapot228, the thread will be for anyone interested in PR as a few of us will be rolling in a squad together as AJSA. The OP will be updated with information about session/training/game times and etc (THIS IS UNOFFICIAL, BUT FEEL FREE TO JOIN IN) Thread here!


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Selling at exhibitions is as different to personal selling as a buffet is to a romantic dinner.
It takes a different set of skills and strategies to succeed.
I used to a lot of work at consumer exhibitions and have probably attended 50-60 in the last 5 years.
My brief to my team on the stands was always: be memorable.
In my industry each exhibition visitor on average talked to at least 20 different companies represented on a variety of stands.
So, my message to my team was: What are you going to do to make sure they remember you?
If they don't remember you at 8pm this evening when they get home, you have not done your job today.
Three tips to help you succeed at your next exhibition:
1) Think about appealing to all of the senses. Lots of stands concentrate purely on looks, without spending enough time working on the other very important senses.
2) What are your people saying to them that is different, or refreshing, with high impact? Messaging is key.
3) The time after the exhibition is so important. Put together a strategy for quality contact. Again, ensure messaging is well tailored.
We have helped out dozens of customers get their approach right for the big day.
Give me a call to discuss lots of different ideas to ensure you are minimising waste and maximising sales from your next event! Our sales training in London, UK and Europe may be the perfect solution for you!


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(At least a little bit)
Rebel Haiku is a creative strategy and marketing training dojo located in Ellicott City, MD.
Full studio set up.
Giant inflatable moon.
War room & main stage.
Cafe and lounge.
Training area & conference space.
Office area.
Every organization struggles to train their people. From in-house marketing staff to the next generation of leaders, training and community is essential to the growth and effectiveness of your top talent.
Invest in your people • Give them a plan • Call them to a higher level.
When we're not training, we're doing. Learn about the offerings and service of Rebel Haiku, the creative consultancy.
787 Oella Ave.
Ellicott City, MD 21043
(443) 917-6080
Wednesday 8:30 – 10:30am
Thursday 8:30 – 10:30am


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Phone & Tablet Repairs
We repair most mobile phones and tablets. Bring in your busted screen or a device that is not working properly for a quick assessment and repair. Repair prices begin at $20.
We repair the following devices:
- Apple
- Samsung
- Nokia
- Motorola
If your device is not listed just give us a call at 08 8725 3366.


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Submitting Your Project to the IRB
Submissions to the IRB must include all of the following:
- COMPLETED IRB Checklist
- Cover sheet including the name of the project, researcher's name and e-mail address, and advisor's name and e-mail address (if applicable).
- A summary of your project in no more than 150 words. (You can review a sample IRB proposal here.)
- Detailed description of the procedural section of the research proposal.
- A reasonably complete sample of the test items, if applicable.
- Consent form and script for obtaining informed consent. (Consent form templates are available on our downloads page.)
- If applicable, script for debriefing research participants. (Debriefing is required where there is either deception or incomplete disclosure of the purpose of the study. If these do not apply, debriefing is nevertheless encouraged for the learning opportunity a debriefing provides participants.)
- If another institution or organization will be involved in your research, include a letter of permission to conduct research from them. (Please note that this does not replace individual consent from your participants.)
Please send an e-mail that includes all of the above as attachments to email@example.com.


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Our client, a highly established market leader in the fire and security industry, has a rare opportunity for an Alarm Technician to join their growing team of technicians both in their Victoria, Regina and Winnipeg locations. The Commercial Alarm Technician will be responsible for installations, renovations and programming of alarm systems at customer sites.
As an Commercial Alarm Technician, you will be responsible for:
To be successful you will need:
Join this team and enjoy:
Don't miss this opportunity to work with an outstanding organization! To apply, kindly submit your resume, cover letters not required.
We look forward to reviewing your resume.
TPD will not share your information with anyone outside of our firm without your approval as privacy and confidentiality are part of TPD's core values.


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it was time for lula to get new prescription glasses. i really wanted to find her some cat eye style vintage glasses, but knew going that route might be tricky. i searched on etsy and found some really cute ones. the prices ranged depending on the condition they were in.
i found these adorable blue ones at pieces of pastimes. julie was kind enough to send them to me courtesy so we could find out how replacing the lenses in vintage glasses would work.
one of the problems with vintage eye glasses is that the plastic becomes crystallized over time and can easily break. these particular glasses were very bent when we received them, and as i tried to gently bend them back, they quickly snapped and broke! bummer! pair one down!
another problem with vintage prescription glasses is that the plastic part yellows over time too...as you can see in the above picture. there are tips all over online for cleaning that up, but i'm not sure if it actually works or not.
i also ordered another pair of pink glitter cat eye glasses hoping at least one of the pairs would work out. these were in a little better shape. in part two, i'll let you know if they worked out!


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BluePearl Veterinary Partners is proud to support the work of Frankie's Friends by participating in Paws for a Cause to help family owned pets in need of lifesaving veterinary care their owners can't afford in New York. Will you help us?
Families are in need of financial assistance to pay for their pets' veterinary care now more than ever before. We're afraid veterinary care will fall to the bottom of the priority list and pets will suffer without proper veterinary care, be relinquished to shelters, or worse... be euthanized... as a result. Families are hurting, and we want to help.
Paws for a Cause supports Frankie's Friends, a nonprofit foundation dedicated to helping pets in need of lifesaving emergency and specialty veterinary care their families can't afford.
Please give $5, $50, or whatever you can, knowing all donations up to $75,000 will be MATCHED. Your donation will help so that families don't have to choose between putting food on their table or saving their beloved pet's life as a result of their financial situation.
Together we can help save more pets' lives.


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This branding and logo design was created to emphasize the three-dimensional designs that Coopers Concepts', an interior design and home renovations company.
Rocket Town Media designed this landing page concept for the 94 Cup Golf Tournament
This Beverly Hills, California builder contacted us to build them a website that truly set them apart from builders in their area and industry, and that showcased their abilities on multiple levels.
The Paulding County Economic Development Council needed a website that not only promoted what they did, but that provided potential new businesses and industry an invaluable tool to learn more about the county, and its available sites and buildings.
Rocket Town created this modern looking site for Bama Jammer Inc., a leading Huntsville-based company that offers promotional products, embroidery, and screen printing services.


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For this Classic Album Review, we take it back to 1969, to pick up a Loretta Lynn classic. The fourteenth release in her hall of fame career, Woman of The World/To Make a Man was released in June, 1969. It was her final album of the sixties. The album would climb as high as number two on the album charts. Both singles (and title cuts) were top five hits. It is also worth noting that the album sold well enough to break the Top 150 on the all-encompassing Billboard Top 200 albums. That was a very good showing for a country music album in 1969.
On the original vinyl release, both sides are led with one of the title tracks/singles. "Woman of The World" on side 1 and "To Make a Man (Feel Like a Man)" on side 2. They also both happen to be two of the best tracks on the album, as well. "Woman of The World" is one of the best Loretta Lynn hits. Apparently, many others thought that, as it climbed to number one in the spring of '69. "To Make a Man (Feel Like a Man)", the album's second single, and opening track of the second side, became a top five hit in late Summer, 1969. A bouncy track that I would describe as a typical Loretta song; in this case telling women how they should treat their men.
Typical of most albums of that era, there are several cover tracks, including "Johnny One Time", a song that both Willie Nelson and Brenda Lee had singles on. I would argue that Loretta's version is as good as the other two versions. Great vocal job, it sounds like it was written with Loretta Lynn in mind. Loretta also does a nice take on the standard "No One Will Ever Know", which Roy Acuff introduced in the late 1940's. "No One Will Ever Know" bounced around for over thirty years before it finally found hit status in 1980, at the hands of Gene Watson.
A couple of more covers are songs that are now classics in country music; Tammy Wynette's "Stand by Your Man" and Merle Haggard's "Today I Started Loving You Again". Loretta's work on "Stand by Your Man" is good, but "Today I Started Loving You Again" misses, largely because the quicker than normal tempo gives it a rushed feel. The vocals are fine, but not enough to save the overall result.
I like the ballad "If You Were Mine to Lose", which features yet another excellent Loretta Lynn vocal performance. "The Only Time I Hurt is a solid, steady track, as is "Big Sister, Little Sister". "Big Sister, Little Sister" starts with how the big sister would always make way for the little sister. Now they're adults, and a man's involved; do you know where this is going? Yep, big sister loves the man, but little sister marries him. Sorry for the spoiler.
"Ten Little Reasons" is classic Loretta. The self-penned tear-jerker is a great track, and is one of the album's highlights. So is the album's wrap-up, "I'm Lonesome for Trouble Tonight". Loretta co-wrote it with Doyle Wilburn of the Wilburn Brothers. Good, solid track to put the wraps on this album.
Overall, a very good collection of vintage Loretta Lynn that easily showcases why she has been one of the genre's legendary performers of the past fifty years. Two strong hit singles featured, here, mixed with several very good-to-excellent album tracks, the best of which are "Johnny One Time" and "Ten Little Reasons". It's not her all-time best album, but it is one of her better long plays (and she's had several good ones to choose from) and very worthy of a four out of five ranking.
Your thoughts?
Saving vinyl one record at a time.
Norma Jean Heaven Help The Working Girl
About Thy Author
Mike the Country Musicologist is a lifelong music and radio fanatic, lover of vintage agriculture, and big sports fan, including the Colts, Reds, Hurricanes, Pacers, Purdue & Butler Universities. He has collected records since childhood, focusing on classic country and top 40 oldies music. After convincing Vincennes University in Indiana to give him an Associate's Degree in broadcasting, he has spent most of his adult life on the radio, having worked for several stations in Indiana and North Carolina, including his current gig, hosting the weekly World Famous Ultimate Twang Radio Show. Hear the show on Thursdays, 4-7p ET on WSFM-LP/AshevilleFM, which is at 103.3 FM in Asheville, North Carolina, as well as online at ashevillefm.org. Be sure to follow him on Facebook, Twitter, Instagram, and Pinterest.


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Submitted by Vivek on the study group =)
Saturday, May 6, 2017
Submissions: Syndromes associated with pheochromocytoma
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Bell styled in White. This vintage icon with its flowing lines and curvy body is a real head turner, adapted for 2/3 passengers, although normally used by the bride and groom. looks stunning with the roof up or down. This elegant wedding car has been converted for easy access for larger dresses and is one most popular wedding car in the UK today.
This car can be booked on it's own for that special wedding day experience or can be booked with Beau or Harvey or Harriet or our Limousine or Executive E Class Mercedes. These cars are highly popular with our customers and we highly recommend that you book very earl to avoid disappointment. Call Gray or Jo or fill out our enquiry form to receive further information.
This car is really popular and booked for many weddings and special occasions and school prom's. We recommend that you book this car early to avoid disappointment.


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Ensure you live your best digital life. Find out if fiber is available in your neighborhood today with our interactive coverage map.
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Here is an amazing recipe for a Halloween Bark that will be the talk of any party you go to. It can be made with leftover Halloween candy.
Happy Halloween! Do you want to take the perfect treat to a Halloween party? Create this Halloween Bark quickly using saltine crackers, butter, brown sugar, chocolate chips, and Halloween candies or cookies.
Halloween Toffee Bark Recipe
Halloween Candy Toffee Bark
- 2 sleeves saltine crackers
- 2 sticks of butter
- 3/4 cup of brown sugar
- 12 oz semi-sweet chocolate chips
- candy corn
- Halloween sandwich cookies
- Halloween sprinkles
- Preheat oven to 400 degrees.
- Line a cookie sheet with a silicone baking mat or parchment paper.
- Lay out a single layer of saltine crackers on the cookie sheet.
- In a saucepan, melt the butter over medium heat.
- Add the brown sugar to the melted butter and stir constantly until the mixture comes to a boil.
- Boil for 3 minutes with a constant stir to create a toffee mixture.
- Pour the toffee mixture over the crackers. Spread out the toffee with the back of a spoon or spatula.
- Put the cookie sheet in the preheated oven and bake for 5 minutes.
- Remove the cookie sheet from the oven and sprinkle the chocolate chips over the toffee.
- After 2-3 minutes, the chocolate chips look glossy. Use a spatula to spread the chocolate across the toffee.
- Break up the sandwich cookies and sprinkle them on top of the melted chocolate.
- Sprinkle on the candy corn and sprinkles too.
- Place the cookie sheet in the refrigerator to harden for at least an hour.
- Break or crack the bark apart into small pieces.
- Store the leftovers in an airtight container.
Doesn't that look good? We call this Crack since it's made out of crackers and it's so addicting. Whenever I take it to a party or event, it disappears quickly. People cannot believe it's made with saltine crackers.
Have you ever had toffee bark?
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Kolkata: In Kolkata, stars descended on Mamata Banerjee's stage for the 23rd Kolkata International Film Festival - with a whiff of politics too - as Kamal Haasan rose to a standing ovation besides Amitabh Bachchan, Shah Rukh Khan, Mahesh Bhatt and Kajol. 144 films from 65 countries will be screened over the next week at 12 different venues. For Kolkata's film lovers, Christmas has come early. The chief minister will miss the movies. She is off to London tonight. "The whole world has come to Bengal today," Ms Banerjee said. "We are very proud. But, I am going to London tonight to participate in Sister Nivedita's 150th birth anniversary celebrations at her home there. English Heritage deferred the programme for me as I was busy with U17 World Cup."
- Amitabh Bachchan, Kajol and others were present at KIFF
- Shah Rukh Khan spoke eight sentences in Bengali at the festival
- KIFF will pay homage to veterans like Om Puri, Tom Alter
Mr Amitabh Bachchan asked Mamata Banerjee not to invite him to the festival any more. He is the chief guest for the fourth time today and said he was running out of ideas for his inaugural speech. However, he spoke movingly today about Bengali cinema's contribution to music in Indian films.
Shah Rukh Khan spoke eight sentences in Bengali to resounding applause and said he would wear a dhoti for the next festival. Kamal Haasan, who many thought may slip in a word about his political plans, spoke briefly on films. Mr Mahesh Bhatt made a more political speech, saying freedom of speech must be protected.
The inaugural film today is Iranian director Mostafa Taqizadeh's debut film Yellow. It has won several awards this year itself, at Shanghai. Yellow is about friends trying to raise money for a liver transplant for one member of the group.
One of the people on stage with Mamata Banerjee today was British director Michael Winterbottom, who will be showcasing six of his films. He is the maker of The Mighty Heart, a film on the US journalist Daniel Pearl who was killed in Pakistan.
KIFF is the second oldest film festival in the country. It will also pay homage to veterans like Om Puri, Tom Alter and Ramananda Sengupta who have recently passed away. They include films like the 1959 film Headmaster whose cinematographer was Sengupta, Shatranj Ke Khiladi, which featured Tom Alter and Om Puri's Sadgati.


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ABUJA: The Independent National Electoral Commission INEC would on Friday meet to take a decision in respect of Thursday's order of the Supreme Court which ordered it to withdraw the Certificate of Return it issued to the Governorship Candidate of the All Progressives Congress APC in Bayelsa state, Chief David Lyon.
The apex court had ordered the withdrawal and consequently directed the electoral umpire to issue the certificate to the candidate with the second highest votes polled in the November 16, 2019 Governorship election.
The court however gave a caveat that the candidate must have met the constitutional spread of votes in at least two-thirds of the local government areas in the state.
However, speaking with Vanguard on Thursday night, Chief Press Secretary to the INEC Chairman, Mr Rotimi Oyekanmi said the commission was not yet in receipt of the enrolled order of the court.
He said; "As at 8pm on Thursday when we left the office, we were yet to get an enrollment order. So, tomorrow (Friday), we will reconvene very early. And once we get the order, we will meet as a Commission and take a decision".