text:
The Independent Electoral Commission's already substantial woes are set to grow.
A company that should have been shortlisted in providing new headquarters for the election planning body is claiming R7.5-million from the IEC, the Mail & Guardian learned on Tuesday.
"A letter of demand has been issued through our attorneys," said David Hewer, chief executive of Midcity Property Group. IEC vice-chairperson Terry Tselane confirmed that the body had received the letter of demand, for R7 516 943.42.
Khwela City Property Services, a company within the group, was incorrectly excluded from the IEC's disastrous leasing procurement process to secure new premises in 2009.
Public protector Thuli Madonsela found in August 2013 that a lease deal in which IEC chair Pansy Tlakula was involved then as chief electoral officer was "irregular … and violated procurement rules". The procurement was for the IEC's Riverside Office Park building in Centurion, Pretoria, to the tune of R320-million.
A subsequent forensic audit report by PricewaterhouseCoopers, commissioned by the treasury, made similar findings.
Incorrect info
The report also found that Stephen Langtry, Tlakula's then manager in the office of chief executive, provided incorrect information to the bid committee, which resulted in Khwela City being prejudiced against and excluded. Abland eventually won the bid. Tlakula's business partner in a separate company – Thaba Mufamadi – owns a stake in that company.
Mufamadi is also Parliament's finance portfolio committee chairperson and an ANC member of Parliament. Madonsela found that Tlakula failed to disclose her business relationship with Mufamadi to her team at the IEC.
Khwela City was omitted from the shortlist in part because they could not meet a building occupation date of April 1 2010. However, the forensic audit noted that Abland, the company that was chosen, also failed on this count.
The forensic audit also found that had Khwela City been awarded the tender, the new offices would have been "cheaper" to rent for the IEC.
Hewer said their claim was based on the findings of the two reports, particularly the "irregularities concerning maladministration, in terms of the procurement with regards to the lease … and the fact that we were prejudiced as a tender party".
The amount being claimed was "around what was tweeted" said Hewer, referring to a tweet by United Democratic Movement (UDM) leader Bantu Holomisa on Monday night, referring to the legal action:
"#IEC in trouble. Today, the company,#Khwela City, which was robbed by #Tlakula's decision is claiming R8m from #IEC. Raise ur hand #ANC," tweeted Holomisa.
The UDM leader originally blew the whistle on the leasing deal, leading to an investigation by the public protector.
Asked why his lawyers were claiming an amount of about R8-million, Hewer said it was what the company had forfeited in terms of commission on the ten-year lease, together with interest from when the IEC would have taken occupation, if Khwela City had won the bid. The owners of the building would have paid the commission.
The letter of demand was issued under the ambit of the "Institution of Legal Proceedings Against Certain Organs of State Act 40 of 2002", which regulates the claiming of debts from any state or constitutional body, like the IEC.
The IEC had thirty days to respond to the letter, according to the Act.
Tselane, who has been tasked with dealing with communicating about the leasing deal in Tlakula's place, said the matter has been referred to the IEC's legal counsel.
The latest shock to the body comes on the back of workers threatening to go on strike if Tlakula does not resign, just weeks before the country's fifth national democratic election. A number of small political parties, led by Holomisa, also called for Tlakula's resignation on Tuesday last week. The incident has caused tensions among the five commissioners leading the IEC and damaged the body's previously impeccable reputation.


text:
Search.medianewtab.com Removal Instructions – Steps To Delete Search.medianewtab.com
Is your PC infected by Search.medianewtab.com virus? Is your browser homepage got replaced by some unknown website? Is your browser automatically getting redirected to Search.medianewtab.com or any other unknown web pages? Are you unable to get rid of this nasty threat? Do you need some help to delete Search.medianewtab.com from your PC? Read this guide to delete this nasty threat from your computer.
Search.medianewtab.com is a scam website regarded as browser hijacker. It can easily infect your computer without permission and leads to several unwanted problems. This malign threat will brutally ruin your web browsing experience and make your system slow. It is able to infect all famous web browsers such as Google Chrome, Opera, Microsoft Edge, Mozilla Firefox, IE and many others. Once infecting your browser, it will modify your browser settings and can also make changes to the start page and default search engine of your browser. Search.medianewtab.com has the only motive to lure innocent users and make illegal profit.
Search.medianewtab.com mostly get inside the compromised PC through malicious websites, bundled freewares programs, Network file sharing, junk email attachments, social media websites and many other deceptive tricks. This nasty threat will completely downgrade your web browsing experience. It can also bring more threats on your machine by redirecting your browser on malicious websites. Search.medianewtab.com will also show several fake and annoying ads on your computer screen. It may also track your browsing habits and online behavior to collect your personal information. It can send your private details to remote hackers to make illegal profit. You are advised to delete Search.medianewtab.com from your PC at the earliest.
Click to Download Search.medianewtab.com Scanner
Harmful Consequences of Search.medianewtab.com Infection
Search.medianewtab.com is a noxious infection which may attack the several versions of major web browsers.
It may hide itself in your PC when you read junk mails and click on intrusive links.
It is capable to take over your current or useful home page and releases lots of annoying messages on the system screen.
It may added as a hazardous add-on or extension to your system browser without any approval.
It will violate the private data and disables the functions your security programs like firewall, antivirus and so forth.
This threat drops creepy files to the PC, so that your system performs very slowly and weirdly
Search.medianewtab.com will make several changes to your files, DNS configurations and some PC's start up process.
It generates strange pop-ups that are constantly popping up in your search pages while you browse the internet.
It has ability to embeds lots of additional plug-ins or add-ons to the browsers and frequently redirects user to other third party or insecure domains by showing multiple annoying pop-ups.
Search.medianewtab.com infection usually tracks your search terms, surfing history and quickly sends to cyber hackers for illegal purposes.
This infection may create sorts of web traffic and it not allows to access of your favorite or valid web pages.
Method 1: Detect Search.medianewtab.com with Automatic Scanner
Removing Search.medianewtab.com manually is a difficult task for the users as you need to detect the fake registry entries, hidden files, folders etc. You should know that these steps are associated with high risk. A single mistake in deleting the files can leads the system to permanent freezing situations. To avoid such troubles, you are recommended to make use of Search.medianewtab.com Scanner. It is one of the best tool available in the market which is capable to remove the malignant threats completely and also protect the system from future attacks.
Step 1: After the successful downloading of the tool, you need to double click on "SpyHunter-Installer.exe" to run it.
Step 2:"User Account Control" dialog box will appear on the screen. You need to click on "Yes" option.
Step 3: Click on "Next" button which will appear during the setup process to install the program.
Step 4: Finally click on "Finish" button. If the program ask you to provide your personal information then add it otherwise accept the default data.
Step 5: Now, open the tool and start the scanning process to detect the presence of Search.medianewtab.com in the system. You can wait until it scan gets completed.
User Guide to Run Automatic Search.medianewtab.com Scanner
Step 1: Once the software gets installed, you need to click on "Scan Computer" to start the scanning process.
Step 2: You can use "Custom Scan" feature to scan in a particular location to detect Search.medianewtab.com and other related threats.
Step 3: This tool provides the feature of "System Guard" to block all the suspicious activities of the system. It will also help the users to protect the Active X, Process control, Registry section etc.
Step 4: "Spyware HelpDesk" will provide you complete details about the available threats like Search.medianewtab.com in the system.
Step 5: It will protect the Windows PC on Networks with the help of "Network Sentry" option. Using this feature, you will be able to block the modification and protect the DNS settings as well as Host file.
Step 6: In order to scan the PC at pre-set time, you can make use of "Scan Scheduler". It will automatically perform scanning even without your interference on weekly, daily or monthly basis.
Method 2: How to Remove Search.medianewtab.com Using Manual Steps
if you have detailed knowledge about the internal files of the system then you can opt manual process to remove Search.medianewtab.com completely from the system. The important points are mentioned below
Step 1: Open Task Manager by tapping Alt+Ctrl+Del keys together. Move the mouse pointer to "Processes" tab. Detect the fake process created by the Search.medianewtab.com and click on "End processes" to terminate them.
You can skip this step if you do not find any file associated with Search.medianewtab.com.
Step 2: Uninstall Search.medianewtab.com programs from the Control Panel.
Remove Search.medianewtab.com For Windows 7| Vista
Click on Start menu and tap Control Panel.
Select "Programs" option and choose "Uninstall a Program".
Detect all the malicious programs associated with Search.medianewtab.com and click on Uninstall button.
Steps to Delete Search.medianewtab.com From Windows 8
On the right edge of the screen, Click on Search button and type "Control Panel". Click on search button.
From the search results, select Control Panel. Its Window will appear on the screen, click on Programs and Features option.
Identify the unknown programs and click on Uninstall button to get rid of Search.medianewtab.com permanently.
Steps to Delete Search.medianewtab.com From Windows 10
Click on Start button.
To show all the contents, you need to click on Settings option.
Tap System.
From the System menu, Choose Apps and Features option.
Find Search.medianewtab.com from the list.
Finally, Click on Uninstall button to protect the system from Search.medianewtab.com.
Step 3: Remove unwanted extensions created by Search.medianewtab.com from the browser.
Remove Search.medianewtab.com From Chrome
Open the Chrome browser and click on menu option.
Go to tools menu and choose extensions.
Detect the unknown extensions and click on Remove button.
Delete Search.medianewtab.com From Firefox
Double click on Firefox browser to open it and click on Menu button. Select Add-ons from the list.
From the Add-ons Manager tab, click on Extensions panel.
Tap the unknown add-ons and finally click on Remove button.
Uninstall Search.medianewtab.com From Internet Explorer
After opening the browser, click on Tools button and choose Manage add-ons.
From the Show tab, detect the fake add-ons from the list.
- Click on Remove button.
Step 4: Open My Computer and go to C drive. Identify the fake files which is created by Search.medianewtab.com and remove them completely.
- %program files% \808-797-2323.exe
- %AllUsersProfile%\LocalStorage\{random}.lni
- %Program Files%\Common Files\EPSON\EBAPI\eEBSvc.exe
- %program files x86%\common files\speechengines\microsoft\ 808-797-2323.dll
- %users%\your user account\appdata\roaming\installplugin\808-797-2323.
- %windows%\system32\drivers\ 808-797-2323.sys
Step 5: Open the Run box by tapping Win+R key together. Type "regedit" to open the Windows Registry Editor. Delete all the fake entries which is created by Search.medianewtab.com.
- HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Enum\Root\LEGACY_WMDMPMSP\"NextInstance" = "1″
- HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Enum\Root\LEGACY_WMDMPMSP\0000\"Class" = "LegacyDriver"
- HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Enum\Root\LEGACY_WMDMPMSP\0000\"ClassGUID" = "{8ECC055D-047F-11D1-A537-0000F8753ED1}"
- HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Enum\Root\LEGACY_WMDMPMSP\0000\"ConfigFlags" = "0″

subset: commoncrawl


text:
What's on the ballot?
Shall the Public Schools of the City of Ann Arbor, County of Washtenaw, Michigan, borrow the principal sum of not to exceed One Billion Dollars ($1,000,000,000) and issue its general obligation unlimited tax bonds for the purpose of defraying the cost of making the following improvements:
- constructing additions to and/or remodeling School District buildings, including safety and security improvements, classrooms, laboratories, kitchens, performing arts and pool facilities, and solar, geothermal and other renewable energy improvements;
- acquiring and/or constructing buildings in the School District, including elementary, middle and high schools;
- equipping, furnishing, reequipping and refurnishing buildings in the School District, including the acquisition of school buses and musical instruments;
- acquiring and installing instructional technology equipment in the School District; and
- acquiring, improving and developing sites, including athletic fields, facilities, structures, parking and playgrounds, in the School District?
The debt millage levy required to retire all bonds of the School District currently outstanding and proposed by this ballot proposal is estimated to be at or below 4.10 mills. The estimated millage to be levied in 2020 to service this issue of bonds is 1.99 mills ($1.99 per $1,000 of taxable value) and the estimated simple average annual millage rate required to retire the bonds of this issue is 3.49 mills ($3.49 per $1,000 of taxable value). The bonds will be issued in multiple series, payable in the case of each series in not to exceed 22 years from the date of issue of such series.
(Under State law, bond proceeds may not be used to pay teacher or administrator salaries, routine maintenance or repair costs or other School District operating expenses.)


text:
Month: June 2018
Power is out.
Updates will be very sparse for a while, but not due to lack of effort. The power people here shut down my house due to an issue with our main power lines and the structure of our meter, I may be offline for the next week, but hopefully no longer.
M:TC 370 – That's How You Cat
Is up:
And my internet is back on, again.


text:
She finally walked away. As it struck her that he wasn't going to change
She told her mother she couldn't go to school. Her eyes were too puffy from crying and her hair was a complete wreck all because he said "we're just friends."
All of the best love stories have one thing in common; ;you have to go against all odds to get there.
People always, always find a way to ask. Do you still like him? & even though i lie and say, "no of course not.. i've moved on!" my anwser is always ;; no matter what, i'll always love that boy.
I LOVE YOU; The three most commonly misused, misunderstood and overused words in the english language.
in three words i could sum up everything i learned about life: it goes on
everything i learned about love: it doesnt last
and everything i learned about people: they change fast
After a while you get sick of caring and you're too hurt to fight. Sometimes, no matter what you do, things won't be alright.
You were never worth it. Now, I only wish my heart knew that.
her heart finally told her, he just isnt worth it anymore


text:
Find even more goodies like ebooks, tshirts, mugs, stickers & more in the Z&F STORE!
Hee hee. Some of my favorite quotes from that movie revolved around Randy in that stupid puffy jacket. "Randy look like a flea about to pop", "Getting ready for school was like preparing for extended deep sea diving", and the infamous "I can't put my arms down!"
Read The Holiday Special from the start by clicking the image below!
What movie are you talking about? Anyways I really like that second panel with the round shape.
Thanks, another compliment on that second panel, yay!
Haven't you heard of "A Christmas Story"? Ralphie Parker and the Red Rider BB Gun?
I love that round second panel and all the detail with the headphones and the striped scarf.
thank you Denny!
I know Zorphbert's talking figuratively about the winter outfit, but I wouldn't put it past the Weird Kid to put a literal "kick me" sign on his own back for reasons inscrutable.
me neither. and he'd probably stick a whoopie cushion in the seat of his pants for more comic value.
Next thing you know, his dad will win a leg lamp…
(*smack…*) (bad sam… bad sam…) (*smack…*) (I'm a bad sam…)
heh heh.. just you wait..
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text:
About the Therapist
Myota Medical Massage
About the therapist
Natasha Garbe
Licensed Massage and Bodywork Therapist
I care. It's that simple.
Natasha's Practice Theory
My practice is based on an integration of ancient Chinese Medical Massage (TuiNa), acupressure, and modern western massage techniques. With a wide breadth of techniques available, your massage will be a delightful combination of techniques. I am able to adjust to any preferences you may have- when you come in for your session, we will work out a plan together.
I went to East-West Healing Arts Institute and interned extensively with an acupuncturist focusing on pain relief and management. I have been in practice since 2010. After graduation, I began running East-West as the School Administrator and later returned as the Dean of Education. I believe in therapy backed by science and continue my personal studies.
My passion for people carries naturally into the work that I do. My previous work in the health care field included direct care of people with developmental disabilities, physical disabilities, Alzheimer's, and dementia; I have an utmost respect for diverse populations that manifests as a drive to help those around me. No one walking into my office is ever judged.
All are welcome here
Why I Do What I Do
I love people. I want to help. And I believe in
Over the course of the past few years, I have watched how massage can be transformative. Pain changes people. Chronic pain is heartbreaking for the patient and the patient's family and friends. I can't promise that I will relieve your pain. But I can promise to try. I've watched the difference that the absence of pain can have. It's beautiful. Whether it is a tight low back preventing sleep, chronic tension headaches, shoulder and neck pain, sciatica, or the pressures of a stressful situation- massage is a natural alternative or excellent companion to traditional pain relief. We will work together to design your massage session to focus on your needs.
[A special note to those nervous or recovering from touch trauma: please know that I will work
you, at your pace and comfort level. Massage is healthcare. You are always welcome to remain clothed or to have someone with you if it would help you]
Natasha as a Person
I love what I do. I'm passionate about massage therapy. And I am filled with gratitude just writing that about my career! When I'm not practicing massage, I'm running my other business -
Honeysuckle Creek Photography
I am taking pre-requisite courses in hopes of continuing on to Physician's Assistant School in the future. I watch people's gate patterns and analyze what muscles may be sore- for fun- everywhere from the mall to the zoo. Once a therapist, always a therapist! I LOVE words. I'm a writer at heart. Now that you know so much about me, please set up an appointment so that I can get to know you! I can't wait to meet you!
In health and happiness,
Natasha Kae Fuller Garbe
Proudly powered by
About the Therapist


text: Though among the Sunnis even faqihs were obliged to imitate and, at times, in discussions of the closure of ijtihad the idea of imitation (taqlid) was considered as a "major benefit" to the ummah, there appeared mujtahids who not only adopted independent fiqhi positions, but also formulated novel usuli theories. Ibn Taymiyyah (d. 728) is the prime example of this tendency, who adopted a Salafite approach while maintaining the continued legitimacy of practicing ijtihad. From a broad perspective, Ibn Taymiyyah should be viewed as a Hanbalite, who dissented from the mainstream Hanbalism on a number of issues. As a true Salafite, Ibn Taymiyyah insisted on a return to the ways of the Salaf (the pious ancients, i.e. the main witnesses of early Islam) in the early days of Islam. However, he was not so possessed with the idea as to ignore the opinions of the founders of major fiqhi schools, Ahmad and Malik in particular. In cases of dissent from certain Hanbalite views he often chose from among the views of other schools. In fact, there were very few cases in which he arrived at a conclusion in conflict with those of all the four fiqhi schools. In his approach to the Qur'an, at times, he adopted a literalist view which led him to a position other than that of the Four. Undermining the value of ijma` was another consequence of Ibn Taymiyyah's Salafite position, though, he did set forth the alternative notion of ittifaq (agreement), i.e. agreement among mujtahids on a point of shari`ah which is based on evidence provided by a religious text (nass). He believed many cases of ijma` to have been the result of ignorance with regard to the existence of opposite points of view. In the main part of his book he discusses a number of ijma` cases offered by Ibn Hazm and lists views which are in conflict with their conclusions.


text:
As I was riding around the campus of George Washington University on this lunchtime bike ride, I happened upon a marker that I hadn't seen before. As I would come to find out, it is The American Meridian Memorial. Located on a small bluff near the corner of 24th and H Streets (MAP) in northwest D.C.'s Foggy Bottom Neighborhood, it was once considered by some to be the center of the world, establishing a geographical line that separated the Eastern and Western hemispheres.
Prior to 1850, different countries measured longitude from different meridians. Because there was no agreement for a prime meridian, the way there is with latitude and the Equator, prime meridians and associated maps were identified in Greenwich, Paris, Rome, and various other European centers. American navigators tended to use either the French meridian at Paris or the British meridian at Greenwich.
Beginning in 1850, the United States established and began to measure distance from the American Meridian. The Federal government officially used this line, which ran along 24th Street, to measure distances on land, survey the West, coordinate the nation's clocks, and record the start of new days.
However, few navigators at that time adopted the American Meridian, as they owned charts that gave distances relative to Paris or London, rather than 24th Street in D.C. In fact, the United States continued to utilize the Greenwich Meridian for longitude at sea. But land surveyors welcomed the ability to measure from the new American Meridian rather that a line that lay across a broad ocean. So as teams of American surveyors and mapmakers ventured steadily westward, those square boundaries of the Western states were all measured in appealing round numbers from the American Meridian.
Oregon would be the first to use the American Meridian in 1859 when it became a state. The southeastern border of the new state would be exactly 42 degrees West of the American Meridian. Colorado Territory in 1861 would be next to use the Meridian, establishing it's eastern (27°W, Am) and western (34°W, Am) borders with the newly established meridian. The eastern border of Wyoming is exactly 27 degrees west of 24th Street, Arizona is 32 degrees west, and the Utah-Nevada border is 36 degrees west
The United States, via an act of Congress, officially abandoned the American Meridian in 1912, when it accepted the meridian at Greenwich as the international standard. Thus, the American Meridian was relegated to history. Today, the meridian marker is one of three reminders in D.C. of the evolution of cartography in this country. Meridian Hill Park was named for a stone obelisk that was erected there along the original prime meridian in 1804. The stone marker there is long gone, but the park named after it remains. And the third remnant of the pre-Greenwich Meridian age is The Zero Milestone, which is located on The Ellipse directly south of The White House. With the advancement of technology, one day the Greenwich Meridian may be a thing of the past as well.


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Most of the people are suffering from obesity problem now-a-days. It happens due to improper diet, habits and eating lots of food at a time, lack of water etc. Sometimes it may also happened due to genetics heredity. This obesity creates lots of several diseases in body like:- Diabetes, Blood pressure, Heart failures etc.
Actually they don't know how to reduce facial fats and they use many other techniques like cosmetics products, herbal products, pills etc but the result is not proper or unsatisfied. If you really want to remove facial muscles then they have to motivates yourself and you should do a proper exercise daily for about 1 hrs in which you have to give 25-30 minutes time in facial exercise. If you think that you loose your obesity with doing exercise alternately or a day in a week then you are wrong because it does not reduce your weight but sometimes it may creates some pains in your body. So you should care yourself first of all.
Some people want to reduce their weight immediately or in a week or a month and they used heavy dieting which makes them so weak. Heavy dieting is not the right way to reduce weight immediately. If you really want to loose your weight and you want to know the techniques then you are in the right place. Here people can know all the proper ways and technique through which they can reduce their weight easily in just few days.
The proper way to reduce obesity is by proper dieting, habits and regular exercises. People have to eat green vegetables, vegetables soup, drink plenty of water, avoid junk foods and unhygienic foods.
Proper diet chart are as follows:
In Morning
2 eggs+1 glass milk+ 2 breads/poha/breads
In Afternoon
1 chapatti+1 small bowl rice+1 small bowl pulse + vegetable + salads + lots of water
In Night
2 chapatti+ vegetables+ salads+ 1 glass of milk
Some people refused to eat breakfast in morning time but it is very bad for health. People must should take heavy breakfast in morning time and light dinner at night time. They have to drink plenty of water about 10-12 glass in a days.
There is another a best method through which they can reduce their weight easily that is the use of PHEN375 pills. After using this proper in right manner for about 3 to 6 months you can reduce lots of pounds which you see difference after using this pills. You can buy this product easily from online. So hurry up! Don't waste time, it's time to reduce your facial muscles.


text:
I've been designing and decorating homes for over thirty years and started my own business in 1997. I am currently an associate member of ASID (American Society of Interior Designers), IDS (Interior Design Society), and NKBA (National Kitchen and Bath Association). I enjoy creating spaces for each of my clients that are both visually stimulating and functionally satisfying. Each project brings new challenges and each its own sense of satisfaction. I never grow tired of seeing the amazing transformation that takes place and the joy and satisfaction of my clients when a project is complete.
Extensively trained at a local design center for 5 1/2 years I received both in depth training as well as "real life" design experience working with new home buyers – guiding their selections from the ground floor up. This included exterior details as well as interior details. I was also the selected designer for all of the spec homes in the DFW area for Toll Brothers – a high volume, luxury builder. As with new home buyers this included everything from exterior details such as: roofing, brick, stone, stucco, lighting, doors, etc.- to interior details such as paint, flooring, kitchen, bath, hardware, lighting, etc. While employed at the design center I became the designer for special design projects which encompassed model homes, store vignettes, commercial design projects and residential design. My design partner and I were awarded the Summit Award and REI Home Design Award at the 2009 Home Solutions National Conference for one of our model homes in San Antonio. In addition to this hands on experience I learned the basic principles of design such as scale and proportion, rhythm and harmony, balance, emphasis and details, lighting and color. It was valuable design training and experience that I've carried with me throughout my career.
In 1997 I began my own business and have been juggling the crazy world of being a small business owner, the demands of interior design and the challenges of raising a family ever since. Now, with my third and youngest child off to college, two married sons and three young grandchildren – the challenge of juggling it all still continues. But, I feel blessed beyond words and hope that in both career and family I can make a positive difference in people's lives.
I firmly believe in the adage, "God first, family second, career third," and though it's a daily challenge I do try my best each and every day. And, when I fail……I take a deep breath, turn it over to the Lord and give it another go.
Visit my Website @ www.sherimartininteriors.com


text:
A woman's risk of developing breast cancer increases with age, with about one in eight women in the United States — or 12 percent — developing invasive breast cancer during her lifetime, according to the American Cancer Society.
But the good news is that more women are surviving the disease, thanks to screening tests, such as mammograms, that help detect cancer early, as well as ongoing developments in causes, prevention and treatment.
"The majority of people who are diagnosed with breast cancer will be cured," says Dr. Clifford Hudis, president of the American Society of Clinical Oncology and chief of the Breast Cancer Medicine Service at Memorial Sloan-Kettering Cancer Center. "As scary as the diagnosis is, that's a fact."
Despite an increased survival rate, the U.S. Centers for Disease Control and Prevention say that less than 73 percent of women get their recommended mammograms. (Be aware that just 5 to 10 percent of breast cancers occur in women with a direct family history, with the majority of cases found in women with no known genetic predisposition.)
The U.S. Preventive Services Task Force recommends a mammogram every two years for women aged 50 to 74; women who are younger may also benefit from mammograms, according to the task force, which suggests talking to your doctor to find out if a mammogram is right for you. "Mammograms remain the gold standard," says Hudis.
Researchers are discovering that weight control and exercise can lead to lower risk of breast cancer — a recent study in the Journal of Clinical Oncology reveals that obese women have four times the risk of developing inflammatory breast cancer, a rare form of the disease that comprises 1 to 6 percent of all breast cancers.
Tamoxifen, a breast cancer drug, and Bazedoxifene, an osteoporosis medication, has been shown to lower the risk of some forms of breast cancer and was recently approved by the FDA for that use, Hudis says.
A study has found that women with early-stage breast cancer who had low levels of vitamin D were more likely to have their cancer recur in a distant part of the body, according to the American Cancer Society. While more research is needed to confirm this finding, and it is not yet clear if taking vitamin D supplements would be helpful, the ACS suggests talking to your doctor about testing your vitamin D level to see if it is in the healthy range.
Dr. Katherine Crew at NewYork-Presbyterian/Columbia is currently exploring how high doses of vitamin D might help prevent breast cancer. In the past she has similarly explored green tea, and plans to do the same with omega-3s.
Memorial Sloan-Kettering has begun offering women a new procedure to more precisely pinpoint and remove small breast cancers that can be detected on a mammogram but not felt in the breast. Called radioactive seed localization (RSL), the procedure reduces the time it takes for doctors to precisely locate and remove the cancer, and its efficacy and safety were reported on in this month's issue of the journal Health Physics.
Following surgery, other treatments may be needed. "We know that while most people are cured by surgery, too many are not," says Hudis. "[Additional treatments] improve the odds."
For women who need radiation after breast-conserving surgery, newer methods are being studied to shorten the length of treatment. Studies are underway to see if they work as well as standard treatments in keeping breast cancer from coming back, according to the ACS.
New chemotherapy
According to the American Cancer Society, researchers are looking for newer, better drugs to combat hard-to-treat advanced breast cancer. A drug class called PARP inhibitors has been developed that targets cancers caused by BRCA mutations, and has shown promise in clinical trials treating breast, ovarian, and prostate cancers that had spread and were resistant to other treatments. Further studies are being done to see if this can also help patients without BRCA mutations.
Targeted therapies
According to the American Cancer Society, about 1 of 5 breast cancers have too much of the growth-promoting protein HER2. These cancers tend to be more aggressive than other types. There are now a number of drugs approved to target excess HER2 protein, such as trastuzumab (Herceptin®) and lapatinib (Tykerb®), and studies are being done to see how best to use these in treating early breast cancer. Researchers are also looking at using a vaccine to target the HER2 protein.
For cancers to grow, blood vessels must be made to feed the cancer cells. New drugs, known as anti-angiogenesis drugs, may be useful by keeping new blood vessels from forming. Some studies have found that breast cancers with many new, small blood vessels are likely to spread more quickly.


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Wednesday, 1 April 2015
Creative Wednesday Its Blue and me ...
Its the first of the month which means a new challenge over at the Creative Expressions blog. This month the design team have been given a range of Phil Martin's Cosmic Shimmer colours and a few of my stamp sets. Therefore there should be loads of inspiration over at the CE blog, click HERE to have a look and see what the new challenge is. It would be great to see some of your work up there and its a brilliant way to get your work noticed!
For today's card I chose the most popular of my stamps to die for the daisy triplet stamp. I started by cleaning a piece of heat resistant acetate with an anti static bag. Next I stamped the image using perfect medium, covered it in cosmic shimmer detail white embossing powder and heat set it. Always remember to let your heat gun get to temperature for a minute before trying to set the embossing powder: this way you avoid warping the acetate by limiting the time it is heated (all heat guns take a minute or so to get get to a heat that will set the powders)
Next I foam mounted the piece over a strip of foundation card that I had covered with CE double sided adhesive and covered with Phil Martins decadent Denim mica. I then added a frame, cut with the outline die from the bevelled glass striplet, in sky blue foundation card. I added a few PVA pearl dots using again Phil's denim and set it aside to dry.
To make the background I sprayed the matching ink spray mister over another piece of the sky blue and also a length of white seam binding. I scrunched the seam binding up so that I got a variegated look if you want a straight colour simply generously scary the length of ribbon until it is completely covered. I dried each piece off with my heat gun then matted the background up using layers of cobalt and more sky blue foundation card.
I tied the ribbon arround the central stamped image and added the sentiment, from my daisy Corner Elements clear stamp set, in CS true what detail embossing powder and cut it out using Sue's take die.put the card together as shown and tied it to the ribbon with a messy bow. Finally I added a dazzler from the new Aqua dazzlers set by Creative Expressions which has four different colours of dazzlers and comes in a large size or as a mixed set with 4 different sizes.
Pop over to the Creative Expressions blog to see what the rest of the design team have come up with using a selection of my stamps and Phil's cosmic colours!
25 comments:
wow, another stunning cardReplyDelete
this one really stands out
This is just lovely John, everything about it including the colours!ReplyDelete
Love it all John, xxxxReplyDelete
Morning John, A gorgeous card, fabulous colours and I'm loving your compilation, especially the detailed powder onto acetate with the coloured and mica'd card underneath, all complemented by the spritzed layer, gorgeous !!ReplyDelete
Lots of love from Patricia xx
Hi John, a really beautiful card, love everything about it, really need to try my heat embossable acetate again, so this has given me the inspiration. have a great day. BxReplyDelete
Morning John,ReplyDelete
Love your beautiful card.
Lovely shades of blue , and a very lovely card.xReplyDelete
Elaine H X
Hi John, a lovely card.ReplyDelete
Hi John,ReplyDelete
A beautiful card, your daisy stamp is just adorable.
Lorna D
WOW! Stunning John, love the spritzed background and your stamp of course lol!ReplyDelete
Beautiful arrangement and although it's all Blue it does not look too much either.
Love & hugs
Jacquie J xxx
Morning JohnReplyDelete
Stunning card again John, where do you get the ideas from - love the background it really pops
Carol x
Super card John, I've never tried heat embossing acetate, so I really should, one of these days.ReplyDelete
An absolutely fabulous creationReplyDelete
Eh up JohnReplyDelete
Beautiful design and terrific blue colour palette. Love the sprayed background to as it give a super effect.
Off to be "scary" to some ribbon now hahaha!
Have a great day.
Ang x
- Anonymous1 April 2015 at 15:21
Liking what you have done here John, love from Jackie xxReplyDelete
Hi JohnReplyDelete
I haven't done any heat embossing onto acetate for ages you've just reminded me how fabulous the finished results look. I love what you've done for the challenge I'm off to see what the others have done x
Hi John,ReplyDelete
I love your card today all except the ribbon(sorry) the rest of the card is beautiful and i really like the dark blue framing the paler colour of blue. I can understand why your daisy stamp is popular as it is a lovely design and can be used in all sorts of cards.
Thank you for todays inspiration
Crafty hugs
Norah (Glenochil)
It's really gorgeous Blue is such a favourite of mine I love the background and feel sure that mine would turn out to be a dribble mess!ReplyDelete
Hi John, wow what a beautiful card again and I love the dies. Take care Jane B.ReplyDelete
Oh wow John this is a gorgeous card. Hugs JackieReplyDelete
Hi JohnReplyDelete
I just love this card. Your stamps are very popular and are a credit to the Creative Expressions Portfolio. Keep up the good work.
Fantastic card and using some fab techniques that I haven't used since I attended project classes which unfortunately have now closed - but feel a misting and scrumpling session coming on!! The Daisy Striplet stamp is lovely - got the skeleton leaves stamp but not this one - may have to remedy that!! xx GailT xxReplyDelete
This is absolutely gorgeous xxReplyDelete
Gorgeous card John, love your matt and layering. Take care, BrendaReplyDelete
Love it allReplyDelete
Janice W


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Times and Seasons had a posting recently that linked to an article by Kathleen Flake called "How to Bury a Prophet". In the article, she mentions how the family wishes were followed, and how one of President Hinckley's sons dedicated the grave even though there were so many Church leaders there.
The article is short, but good reading, and the comments at Times and Seasons were also good.


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Ace Waste's process will produce 90% less landfill waste than alternative solutions based on Treatment/Landfill operations and completely destroy potentially highly infectious waste. In the use of Incineration waste disposal is proven to be more environmentally effective and produces 24 times less greenhouse gas emissions than treatment landfilling operations.
Ace Waste High Temperature Incineration is the vanguard technology for the secure disposal of difficult wastes which require total destruction. Ace Waste advocates that certain wastes types must be managed correctly to ensure that they are completely destroyed and provide no potential to be released to the wider environment.
Our state of the art stepped hearth Incineration processing facilities have a 1500 kg per hour capacity to process all prescribed waste in an effective and environmentally sound manner. The plants are of multi-chambered design and utilise the significant calorific (energy) value inherent in Clinical and Related, Cytotoxic, Pharmaceutical, Regulated, Prescribed Industrial and chemical wastes to assist combustion.
At our facilities in Queensland and Victoria, Ace Waste processes waste at temperatures up to 1200°C ensuring complete combustion and destruction of hazardous waste materials. Our process starts with an assessment of your waste, we then segregate wastes into categories determined by their calorific value. Our extensive skills and knowledge in understanding the characteristics of different waste enables us to blend waste streams to ensure optimal combustion efficiencies. This practice maximises performance of our Incinerators to the stage of self-combustion and no longer requiring supplementary fuel, this in itself is a major contribution in reduction of Global Warming, emission controls and Environmental Sustainability.
The Ace Waste incineration facilities have the ability to incinerate 10,000 tonnes for Brisbane and 11,200 tonnes for Melbourne per annum.
The two most common disposal methods for the disposal of Clinical and Related Waste are High Temperature Incineration and Autoclaving/Landfilling. Ace Waste can demonstrate that High Temperature Incineration is a more environmentally friendly disposal process than Autoclaving/Landfilling.
In fact Methane is 24 times more potent than CO2 as a Green House Gas, and so 1 tonne of emitted Methane will be expressed as 24 tonnes of CO2e emitted.


text: This came across my Facebook feed today, and I thought it might be of use to people here. It has information and resources from the ACLU for immigrants, Muslims, LQBTQ people, journalists, protestors, people interacting with police, sexual assault survivors, people in need of reproductive care and people with disabilities. Perhaps someone might want to share it to the Salad Bowl, as well?


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What: Classes encourage children to explore the joy of making music in the early stages of education.
When: Term time Saturdays 8:55-9:55am (see term dates)
Cost: see https://pcym.org.uk/feesbursaries
How do I join: https://pcym.org.uk/application-form
More info: Email – email@example.com
Progression: When students turn 7 years old, they will have the opportunity to trial and move up into the PCYM Core Curriculum when they, parents and teachers feel ready for this next step.
Ukulele or Recorder
Through Ukulele or Recorder they will acquire
simple skills and fine muscle control
necessary to develop technical proficiency
on an instrument.
Instruments: Children can bring their own
or borrow one during the sessions.
Instrument will also be available to buy
direct from PCYM.
Ukulele Tutor: Jeremy Sparks
Recorder Tutor: TBC
In addition, students can also take advantage of an individual or shared instrumental lessons should they feel ready for this step in their musical journey. Please ask for more information.
Singing, rhythm and
movement teach an instinctive connection
between what these young musicians do
with their hands, voices, eyes, ears and
intellect. This sense of connection is the
crucial foundation for learning music.
Tutor: Jessica Summers


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Xiaomi Black Shark 2 Hands On Video Leaked Online
Razer has launched its 2nd generation gaming smartphone called the Razer Phone 2. Now Xiaomi is all set to launch its 2nd generation gaming smartphone called the Back Shark 2. The Xiaomi BlackShark 2 has now been leaked in a hands-on video online. The video shared by Slashleaks doesn't reveal much about the upcoming gaming smartphone from Xiaomi. The video shows… Read More


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On August 29th, Zs held their 10 year anniversary show. Extra Life and Wet Ink Ensemble played, but it was way passed my bedtime to stick around. So here are some pictures of the first half with Sam's solo project and what Ben Ratliff called the "constant dogfight of alternate picking and single-stroke rolls".
Diamond Terrifer
Marc Edwards + Mick Barr
(now on facebook)
Brandon Stosuy + Robin DJed (Karlynn too, but not pictured)


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Holiday in Grampians. What to see.
Australia has many wonders up its sleeve. If you will just take the time to discover what these are, you will realize that you will not run out of things to do in this country. And, one of the most loved places you should experience is the Grampians National Park.
It is the place to be if you are the kind of person who loves art and nature. Although it is not often that these will go together in one place, in the Grampians you will be treated to all these and more.
Mountain Landscapes
Since the middle part of the 1900's, the Grampians has been known as a magnet for people who loves to indulge in outdoor activities, especially rock climbing. This is because of its diverse mountain landscapes that offer different kinds of challenges to climbers, newbie and pro alike.
There are craggy slopes that are perfect for first-time rock climbers and rock formations that are so sheer, professional climbers from around the world come here to conquer them. The Grampians offer four of the best mountain ranges in the world and these are the eastern Mount William, the northern Mount Difficult, the south-western Mount Victoria and the south-eastern Mount Serra.
Art and Culture
Contained in the National Heritage List of Australia, the Grampians National Park is also known for its prehistoric rock art paintings. These are said to be done by the country's first dwellers, the Aborigines, which are known to have been residents of the region since 32,000 years ago. Because of this, the Grampians is also known by another name, which is Gariwerd.
If you wish to look at these paintings, you will find them in the shelters that dot the park. These are names the Manja, the Gulgum Manja, the Ngamadjidj and the Billimina. Through the paintings, you will definitely discover the history of the Aborigines in the country.
Flowers and Beauty Galore
If you are more of a nature lover who loves to take things slow and easy, then a walk along the forest valley found between the ranges of Victoria and Serra would be perfect for you. Here, you will find a beautiful stretch of wildflowers such as the Grampians boronia and blue pincushion lilies. There are also various types of herbs and shrubs growing in the region, lending to its beauty.
As you take your walk, you will also be able to come across lookouts that will let you take in some of the wildlife prevalent in the country. Among these are kangaroos, edge-tailed eagles, emus and koalas.
So, if you ever wish to discover more of Australia and its natural and man-made wonders, try visiting the Grampians. It is definitely one stop that you will never regret taking. Great accommodations are available for you to reserve right in Grampian regions. You can choose a cottage with a private view or you might rather choose a hotel with fine service. Whichever you would choose, you can do so easily by going online. Plan ahead for the best traveling you can imagine to the Grampians in Victoria.


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St. Christopher's Hospital for Children has a highly qualified team of bone marrow transplant specialists who are specifically trained to work with the individual and unique needs of infants and children. The team consists of transplant physicians, radiation oncologists, oncology nurses, social workers, pediatric registered dieticians and child life specialists provide comprehensive care and support for your child and family.
If your child is suffering from leukemia, lymphoma or other disease of the immune system, or has a bone marrow disorder or metabolic disease, a bone marrow transplant may be necessary to improve your child's health and quality of life.
Bone marrow transplants involve replacing diseased marrow with healthy marrow, injected into the bloodstream via an intravenous tube. The marrow may come from a healthy donor or healthy stem cells may be collected from your child.
For more information or to schedule an appointment, please call (215) 427-4669.


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Coursework/College coursework/Coursework services
Coursework constitutes academic assignments that are done independently from end of term or semester tests and evaluations. Coursework provides a continuous form of assessment that is carried out under both formal and informal contexts. The use of coursework is mainly to assess the academic progress that students might be making in the day to day studies. Coursework constitutes of assignments such as experiment essays and reviews of books, movies and scholarly papers.
College Coursework Service
In today's busy academic environments students usually find themselves overwhelmed with a lot of coursework assignments. They find that they are unable to complete their works it time or at least write their coursework in a proficient manner. In higher institutions of learning there is great emphasis that is laid on the continuous coursework assessments, because they contribute a great deal to the score that a student may attain at the end of the semester or year. A certain portion of the final grade's score is dedicated to the assignments that constitute the coursework offered.
Coursework Writing Help
Students now need not worry any more because there are numerous service providers that can offer these services at an affordable price that is favorable billed for students in terms of the number of pages that they order. The integrity as well as quality of the work offered by these firms is hard to establish and therefore; students are advised to look out for various qualitative aspects that can enable them to determine how well a company can serve their needs in coursework writing. As a matter of qualitative check, a high quality company should be able to deliver their work in time so as to enable them to review their work and either make submission or return it for revision.
Coursework Writing Service
Timeliness is of essence because it is the only way that students can ensure that they do not get penalized through nullification or score reduction. It is also a common thing for the tutor or lecturer to conduct a plagiarism check on any work that is submitted for evaluation. This check of originality is meant to determine whether the work is originally a composition of the student or work that has just been copy pasted. Cases of plagiarism attract stiffer penalties and may be costly to any student, and this may indeed be a big loss on the student's side because she or he will not only fail to get a better score, but also lose his or her money. As a result, the online writing firms that customize coursework should be able to offer high quality original work, not only as a matter of integrity maintenance but also as a way to keep their clients trust in them. The maintenance of confidentiality and privacy is also an essential aspect in the provision of high quality services in the field of coursework writing.
The determination of a firm's quality may not be as easy, because most of the companies offering coursework writing are online based. However, the students still have one possible method to determine the quality of any company that offers coursework writing. The act of conducting a simple survey on the clients that may have procured services from a company can help one in determining whether the company can offer better quality services. This is an essential thing to do before anyone can place an order fro any coursework service provision, because it ensures that one gets the best quality services.


text: A collection of images from Nobody's Home - an exhibition depicting abandoned croft houses across the Outer Hebrides. During 2016 Nobody's Home was staged in Dunfermline, Cumbria and Glasgow. Images from the exhibition, and the stories behind them, have been featured in several publications and also on the radio and TV. A selection of prints from the Nobody's Home collection is now available. Choose from prints or framed and ready to hang wall displays in the online print shop.


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Medical Editor: John P. Cunha, DO, FACOEP
Aggrastat (tirofiban hydrochloride) is an antiplatelet drug that works by keeping platelets in the blood from coagulating (clotting) used to prevent blood clots or heart attack in people with severe chest pain or other conditions, and in those who are undergoing an angioplasty procedure (to open blocked arteries). Common side effects of Aggrastat include:
- nausea,
- stomach pain,
- runny or stuffy nose,
- cough,
- sore throat,
- headache,
- dizziness,
- blood in the urine,
- excessive sweating,
- pelvic pain, or
- water retention.
Tell your doctor if you have serious side effects of Aggrastat including:
- nosebleed or other bleeding that will not stop;
- black, bloody, or tarry stools;
- coughing up blood or vomit that looks like coffee grounds;
- chest pain or heavy feeling,
- pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
- sudden numbness or weakness, especially on one side of the body;
- sudden headache, confusion, problems with vision, speech, or balance;
- fever, chills, body aches, flu symptoms; or
- pale skin, easy bruising or bleeding, weakness, fever, and urinating more or less than usual.
Aggrastat is administered intravenously in a clinical setting, at an initial rate of a 0.4 mcg/kg/min dose for 30 minutes and then continued at 0.1 mcg/kg/min. Aggrastat may interact with phenytoin, tamoxifen, tolbutamide, torsemide, fluvastatin, blood thinners, or other medications used to prevent blood clots. Tell your doctor all medications you use. Tell your doctor if you are pregnant or plan to become pregnant during treatment with Aggrastat and aspirin. Aggrastat is not expected to be harmful to a fetus. However, aspirin is sometimes given with Aggrastat, and aspirin can cause bleeding when taken during the last 3 months of pregnancy. Aspirin can also cause side effects in a newborn baby. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.
Our Aggrastat (tirofiban hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
IMAGESSee Images
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Tirofiban increases your risk of bleeding, which can be severe or life-threatening. Call your doctor or seek emergency medical attention if you have:
- easy bruising or bleeding (nosebleeds, bleeding gums);
- bleeding around your IV or catheter; or
- any bleeding that will not stop.
You may also have bleeding on the inside of your body, such as in your stomach or intestines. Call your doctor at once if you have bloody or tarry stools, or if you cough up blood or vomit that looks like coffee grounds. These could be signs of bleeding in your digestive tract.
Common side effects may include:
- dizziness;
- slow heart rate;
- leg pain, pelvic pain; or
- swelling, increased sweating.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Aggrastat (Tirofiban HCl)
QUESTIONSee Answer
Clinical Trial Experience
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.
In the PRISM (Platelet Receptor Inhibition for Ischemic Syndrome Management), PRISM-PLUS (Platelet Receptor Inhibition for Ischemic Syndrome Management — Patients Limited by Unstable Signs and Symptoms) and RESTORE (Randomized Efficacy Study of Tirofiban for Outcomes and Restenosis) trials, 1946 patients received AGGRASTAT in combination with heparin and 2002 patients received AGGRASTAT alone for about 3 days. Forty-three percent of the population was > 65 years of age and approximately 30% of patients were female. In clinical studies with the recommended regimen (25 mcg/kg bolus followed by a 0.15 mcg/kg/min maintenance infusion), AGGRASTAT was administered in combination with aspirin, clopidogrel and heparin or bivalirudin to over 8000 patients for typically ≤ 24 hours. Approximately 30% of the population was > 65 years of age and approximately 25% were female.
PRISM-PLUS Regimen
The incidences of major and minor bleeding using the TIMI criteria in the PRISM-PLUS study are shown below.
Table 2: TIMI Major and Minor Bleeding in PRISM-PLUS
|Bleeding (TIMI Criteria)‡ §
|AGGRASTAT* + Heparin
|Heparin alone
|Major Bleeding
|Minor Bleeding
* 0.4 mcg/kg/min initial infusion; 0.10 mcg/kg/min maintenance infusion.
‡ Major = Hemoglobin drop of > 5.0 g/dL with or without an identified site, intracranial hemorrhage, or cardiac tamponade.
§ Minor = Hemoglobin drop of > 3.0 g/dL with bleeding from a known site, spontaneous gross hematuria, hematemesis or hemoptysis.
The incidence rates of TIMI major bleeding in patients undergoing percutaneous procedures in PRISM-PLUS are shown below.
Table 3: TIMI Major Bleeding Associated with Percutaneous Procedures in PRISM-PLUS
|AGGRASTAT + Heparin
|Heparin alone
|Prior to Procedures
|Following Angiography
|Following PTCA
The incidence rates of TIMI major bleeding in patients undergoing coronary artery bypass graft surgery (CABG) in PRISM-PLUS within one day of discontinuation of AGGRASTAT were 17% on AGGRASTAT plus heparin (N=29) and 35% on heparin alone (N=31).
Recommended ("High-Dose Bolus") Regimen
Rates of major bleeds (including any intracranial, intraocular or retroperitoneal hemorrhage, clinically overt signs of hemorrhage associated with a drop in hemoglobin of > 3 g/dL or any drop in hemoglobin by 4 g/dL, bleeding requiring transfusion of ≥ 2 U blood products, bleeding directly resulting in death within 7 days or hemodynamic compromise requiring intervention) were consistent with the rates observed in subjects administered the PRISM-PLUS regimen of AGGRASTAT. There was a trend toward greater bleeding in ST segment elevation myocardial infarction (STEMI) patients treated with fibrinolytics prior to administration of AGGRASTAT using the recommended regimen during rescue PCI.
The incidences of non-bleeding adverse events that occurred at an incidence of > 1% and numerically higher than control, regardless of drug relationship, are shown below:
Table 4: Non-bleeding Adverse Reactions in PRISM-PLUS
|AGGRASTAT + Heparin (N=1953) %
|Heparin alone (N=1887) %
|Body as a Whole
|Pain, pelvic
|Reaction, vasovagal
|Cardiovascular System
|Dissection, coronary artery
|Musculoskeletal System
|Pain, leg
|Nervous System/Psychiatric
|Skin and Skin Appendage
Patients treated with AGGRASTAT plus heparin, were more likely to experience decreases in platelet counts than were those on heparin alone. These decreases were reversible upon discontinuation of AGGRASTAT. The percentage of patients with a decrease of platelets to < 90,000/mm3 was 1.5%, compared with 0.6% in the patients who received heparin alone. The percentage of patients with a decrease of platelets to < 50,000/mm3 was 0.3%, compared with 0.1% of the patients who received heparin alone.
Post-Marketing Experience
The following additional adverse reactions have been identified during post-approval use of AGGRASTAT. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to the drug exposure.
Severe allergic reactions including anaphylactic reactions have occurred during the first day of AGGRASTAT infusion, during initial treatment, and during readministration of AGGRASTAT. Some cases have been associated with severe thrombocytopenia (platelet counts < 10,000/mm3). No information is available on the formation of antibodies to tirofiban.
Read the entire FDA prescribing information for Aggrastat (Tirofiban HCl)
SLIDESHOWSee Slideshow
© Aggrastat Patient Information is supplied by Cerner Multum, Inc. and Aggrastat Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.


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A man swerved and crashed his car into a tree while playing the popular Pokémon Go game.
The incident happened Tuesday night in Auburn, N.Y., and it comes as police and transportation departments across the country are warning players to use caution when using the popular new app on their phones.
Police in Auburn said that the crash happened just before 11 p.m. and that the driver "admitted to actively playing" Pokémon Go "while driving causing him to become distracted and run off the roadway into a tree."
A photo that the police department put out shows a very crushed front end of a car.
"Luckily," police said in a statement, the driver "was not seriously injured but this is an example of how easily accidents can occur when someone is engaged in the game and not paying attention."
The investigation into the Auburn crash is ongoing, police said. Officials reminded people that "using common sense while playing the game should be paramount above everything else."
In Washington, D.C., the game has also created controversy with people playing it at popular tourist sites, including the Holocaust Memorial Museum and at Arlington Cemetery.


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Showing changes from revision #9 to #10:
Removed | Chan
Batanin's -operads are described by their operator categories which are called globular theories.
A finite planar level tree ( or for short just a tree) is a graded set endowed with a map decreasing the degree by one and such that all fibers are linearly ordered.
The following -construction is due to Batanin.
Let be a tree.
A -sector of height is defined to be a cospan
denoted by where and are consecutive vertices in the linear order .
The set of -sector is graded by the height of sectors.
The source of a sector is defined to be where are consecutive vertices.
The target of a sector is defined to be where are consecutive vertices.
To have a source and a target for every sector of we adjoin in every but the highest degree a lest- and a greatest vertex serving as new minimum and maximum for the linear orders . We denote this new tree by and the set of its sectors by and obtain source- and target operators . This operators satisfy
as one sees in the following diagram depicting an "augmented" tree of height
which means that is an -graph (also called globular set).
Now let denote the globe category whose unique object in degree is , and let denotes the linear -level tree.
Then we have is the standard -globe. (Note that the previous diagram corresponds to the standard globe.)
Let be a monomorphism.
is called to be cartesian if
is a pullback for all .
Let be level trees.
(1) Any map is injective.
(2) The inclusions correspond bijectively to cartesian subobjects of .
(3) The inclusions correspond bijectively to plain subtrees of with a specific choice of -sector for each input vertex of . (…)
(1) The category defined by having as objects the level trees and as morphisms the maps between the associated -graphs. These morphisms are called immersions. This category shall be equipped with the structure of a site by defining the covering sieves by epimorphic families (of immersions). This site is called the globular site.
(2) A globular theory is defined to be a category such that
is an inclusion of a wide subcategory such that representable presheaves on restrict to sheaves on .
(3) Presheaves on which restrict to sheaves on are called -models.
The forgetful functor
is an equivalence of


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Get MemeStreams Stuff!
"We believe Apple is looking to merge iOS (iPhones/iPads) with OS X (Macs) into a single platform for apps and cloud services starting in 2012-13," Jefferies writes. "Our preliminary view is that Apple can use a 32-bit ARM architecture to address the vast majority of the OS X ecosystem's needs in 2012-13 except for high-end professional devices. When 64-bit ARM is available in 2016, we believe Apple will have a single OS and hardware architecture."
While the iPad 2 uses the Apple A5 chip with a dual-core ARM processor, Jefferies speculates that "Apple is ready to start sampling the A6 quad-core app processor and will be the first such multi-device platform capable of PC-like strength."
Jefferies predicts the iPad 3 will launch with the A6 chip in Q1 2012, while an A6-powered iPhone will launch next summer. The MacBook Air will get the A6 in the second half of 2012 or in 2013, but the higher-powered MacBook Pro laptops and Mac desktops will stick with 64-bit Intel chips until 2016, the analyst firm says. 64-bit chips allow greater use of memory and are useful for "computationally-intensive programs like Adobe's Creative Suite."
Apple to have one OS for Macs and iPads by 2016


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Global Economic Scenarios Ranked
22/02/2011 at 6:30 am Leave a comment
The Canadian economy finished 2010 on a stronger footing than expected, but economists continue to remain on alert, hoping a firm global economic recovery will take hold before the next crisis hits. Threats from black swan events, such as the BP oil spill that threatened to derail the world's largest economy last year, can never be predicted — which is just as well. After all, when it comes to what could happen in 2011, there are already enough major risks on the radar to keep central bankers up at night. Canadian Business ranks the "biggies" here.
Entry filed under: Business, Economy. Tags: Canadian Business, Economy, Global Double Dip, Global Recovery, Greenback, Housing Crash, Inflation, Oil Prices, Trade War.
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Are you looking for a professional roofing contractor to do roof repairs or roof replacement in Mukilteo? There are a lot of companies out there, so it can be difficult to know which one is best for your roofing needs. Don't become frustrated with the search for a good roofing contractor. Here are several tips intended to help you find a reliable roofing professional in Mukilteo.
Ask for Advice
The best way to find a reliable professional roofer in Mukilteo is to ask people you know for advice. Probably one or more of family members, friends, neighbors, or co-workers can refer to you a company or individual they've worked with in the past.
Research Your Options
Getting advice from people you know is a good start, but the work isn't over yet. Once you have a good list of potential roofing contractors, it's time to research them. You can do this by looking at their company websites. Verify that each one offers the services you need before considering them further. Some sites will list pricing information, but you'll likely need to call for a quote.
Read Customer Reviews
Customer recommendations are a great way to assess the work of prospective roofing contractors in Mukilteo. Spend some time reading through testimonials and reviews for more insight about previous performance. It's also acceptable to request a referral list from the roofing contractor.
Looking for a Professional Roofing Contractor in Mukilteo?
If you need a roof inspection, roof repair, or roof installation, it's time to find a professional roofing contractor in Mukilteo. Don't wait to get the assistance you need. Contact Sno-King Roofing & Gutters today. We offer a wide variety of roofing and gutter services. Visit our website for more information about our company or call (855) 736-4446 to schedule an appointment with one of our roofing contractors.
Edited by Justin Vorhees
Professional Roofing Contractor
Serving Customers in Mukilteo, Mill Creek, Everett, Lake Forest Park, Edmonds, Woodinville, Lynnwood, Kenmore, Lake Stevens, Snohomish, Mountlake Terrace, Shoreline, Woodway, Bothell, and Brier


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An otl file extension is related to the NoteTab program. An otl file contains template.
There is one other file type using
the OTL file extension!
.otl - Ventura Publisher type foundry outline editor file
Software that open otl file
OTL file extension - NoteTab template
What is otl file? How to open otl files?
File type specification:
The otl file extension is associated with NoteTab, a text and HTML editor for Microsoft Windows operating system, developed by Fookes Software Ltd.
The otl file stores template from the NoteTab.
The default software associated to open otl file:
Company or developer:
Fookes Software Ltd.
NoteTab is a leading-edge text and HTML editor. Winner of software industry awards since 1998, this application does it all: it easily handles a stack of huge files; lets you format text to your heart's content; does system-wide searches, and multi-line global replacements. It even corrects your spelling mistakes.
List of software applications associated to the .otl file extension
Recommended software programs are sorted by OS platform (Windows, macOS, Linux, iOS, Android etc.)
and possible program actions that can be done with the file: like open otl file, edit otl file, convert otl file, view otl file, play otl file etc. (if exist software for corresponding action in File-Extensions.org's database).
Click on the tab below to simply browse between the application actions, to quickly get a list of recommended software, which is able to perform the specified software action, such as opening, editing or converting otl files.
Software that open otl file - NoteTab template
Programs supporting the exension otl on the main platforms Windows, Mac, Linux or mobile. Click on the link to get more information about NoteTab for open otl file action.


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TYR Pro Swim Series at Bloomington is one month away
With three meets already in the books, the 2018-2019 TYR Pro Swim Series will move to its second-to-last destination in Bloomington, Ind., one month from today. With plenty of fast swims already being posted during the first three meets in Knoxville, Des Moines and Richmond, Bloomington should feature another fast field.
Here are four reasons to buy tickets and head to Bloomington next month:
- World record watchThere haven't been any world records set yet in the first three stops of the TYR Pro Swim Series – could Bloomington feature the first? Each meet has gotten progressively faster and more competitive as we have gotten further into long course season, so a world record could definitely be a possibility.
- Another opportunity for Trials cutsThe 2020 U.S. Olympic Trials are only 14 months away, and that means every long course meet is a valuable opportunity to qualify for the biggest meet on U.S. soil that only comes around every four years. Whether you're trying for your first Trials cut, are trying to add another event, or you're a seasoned Trials veteran, getting those cuts out of the way early can certainly be a sigh of relief and allow you to focus on making bigger improvements as Trials approach next summer.
- The most National Teamers you'll find in one place besides the roster on USA Swimming's websiteSome of the finals heat sheets at the recent Pro Swim Series meet in Richmond read more like an all-star team roster. With Olympic gold medalists, world record holders and world championship medalists littering the heat sheets – names like Katie Ledecky, Leah Smith, Simone Manuel, Amanda Weir, Caeleb Dressel, Ryan Murphy, Chase Kalisz – there's no better place to see the top names in the sport all in one place. Many of these swimmers aren't just battling for fast times, but cash as well, which always adds a bit of extra incentive.
- Who will emerge as a name to watch?
The next Olympic Games are just over a year away. For those aiming to qualify for their first, second or even fifth Olympic team, this summer has the potential to really solidify who the contenders are to make the team. Which up-and-coming swimmers will emerge from the Pro Swim Series meets as a legitimate contender? There are two meets left in the series to see who the challengers will be heading into the rest of this summer and next.
Emily Sampl | USA Swimming Contributor


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Rabat city
The Imperial city of Rabat
The capital of Morocco is located on the Atlantic coast in the north-west of Morocco, the site is the product of a rich exchange between the Arabo-Muslim past and european modernism.
The inscribed city encompasses the new town conceived and built under the French colony from 1912 to the 1930, including royal and administrative areas, residential and economic developments and the Jardins d'Essais botanical and pleasure gardens.
It also encompasses historic parts of the city dating back to the 12thcentury.
The new part is one of the largest and most ambitious modern urban projects built in Africa in the 20th century and the most complete.
The older parts include Hassan Mosque (begun in 1184) and the Almouahad ramparts and gates, the only surviving parts of the project for a great capital city of the Almouahad caliphate as well as remains from the Andalusian, or Moorish principality of the 17th century.
Rabat main sights
- Mausoleum of Mohammed V
- Mohammed V University
- Hassan Tower
- Chellah necropolis
- Kasbah of the Udayas
- Rabat Archaeological Museum
- OLM Souissi Stage


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Take advantage of Ahmedabad car rental services. BookCab offers Ahmedabad taxi cab services at very competitive prices. Our extensive cab network in Ahmedabad allows you to board the cab from any locality in Ahmedabad. Ahmedabad is one of the popular cities in Gujarat State located in West India. Ahmedabad has may sight-seeing places to offer.
Jalore is one of those places that do not need an extensive introduction. Jalore is a well known city located in the Jalore district of Rajasthan. Jalore has lot in store for anyone visiting it. There are many popular places to visit in Jalore. The main languages spoken in Jalore are Hindi.
Planning on a trip by road? Sounds good, however hiring a car from Ahmedabad to Jalore can get very tedious, especially during holiday breaks, if one has not planned in advance. Well the easiest way to do so is to log onto www.bookcab.in and book your cab for the time span you're looking at. One can even avail ongoing discounts or packages which Bookcab may have during the said time period. Bookcab, has a range of cabs to choose from Tata Indica to Rolls Royce, as per your requirements. You can book a cab at any time from Ahmedabad to Jalore and back and be assured of the best of cars and service from Bookcab. So friends, get going and check it out!
BookCab offers Ahmedabad to Jalore car rental service at great deals. Bookcab is India's leading chauffeur driven car hire company that provides the best Ahmedabad to Jalore taxi experience. Bookcab gives a new definition to the online cab booking system from Ahmedabad to Jalore with reliable and on-time cab services. We at Bookcab provide a wide range of cab services from Ahmedabad to Jalore. We have a young fleet and experienced chauffeurs. Bookcab provides affordable and reliable taxi services from Ahmedabad airport to Jalore. Hire a taxi from Ahmedabad railway station to Jalore. Bookcab is the best car rental platform, if you want to travel only one way in taxi from Ahmedabad to Jalore. Ahmedabad to Jalore route is spread over a distance of 315 Km and travel duration is approximately around 5 hours 23 mins. Thinking what is the weather in Jalore? Check out the weather info, while travelling from Ahmedabad to Jalore at Bookcab. Get accurate and reliable weather information and weather updates here. Wondering where to stay in Jalore? Bookcab has got all the details of Hotels in Jalore. Get the list of hotels in Jalore with contact details and addresses. Find detailed information on 2 star, 3 star, 4 star, 5 star, budget, cheap and heritage hotels in Jalore.
We also provide one way taxi services from Ahmedabad to Jalore.
Please click here to find taxi fare from Ahmedabad to Jalore for all kinds of vehicles.
(0)92 4100 4100


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Following up on their webinar of May 2013, the Urban Libraries Council, in collaboration with communications firm The Hatcher Group, has released their briefing paper Libraries, Publishers and Public Access to E-Books, as well as a two-page summary document.
The papers are aimed squarely at policy makers, and "can be used as resources to educate local, national and civic leaders in your community". The key messages in the paper are:
- Equal access to materials
- Publishers' policies are preventing the public from accessing e-books
- Borrowing e-books from libraries is increasingly popular
- Some book publishers are denying libraries access to e-books, while others significantly overprice titles
- Pilot programs are encouraging, but need to be more widely implemented
The webinar podcast, briefing paper and summary paper are available together from the ULC's website


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PolyPockets and PolyCorners - self-adhesive welded pockets are designed to offer a simple and easy method of holding a date or label card in your paperback or hardback book. Available in rolls of 500 Initially repositionable - turning permanent.
- Multiple uses around the home or office.
- Environmentally friendly.
- An excellent way to avoid obscuring text and title pages.
- Simple to mount – initially repositionable, turning permanent.
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We are in for an interesting weekend, as the failed Russian Mars probe Phobos-Grunt is experiencing it's last days of existence. Gradually having come down over the past two months, it is expected to re-enter and burn up (but perhaps not completely) in the Earth atmosphere on Sunday or Monday.
Several days before the re-entry date, it is still not possible (whatever some news outlets erroneously write) to pinpoint when and where it will come down. At the moment of writing (early Friday), the SSC prediction amounts to a still over a day wide window between 15 Jan 02:40 and 16 jan 07:40 UTC. Harro Zimmer's latest prediction is for Jan 15 between 9:00 - 15:00 UTC. Both predictions encompass multiple revolutions around the earth. Please note: all these time windows can still shift, depending on actual developments in space weather (solar activity) and other factors.
Below video has been posted here before, and shows a Fobos-Grunt pass filmed by me from Leiden, the Netherlands, on November 28:
THE SECRET SPIES IN THE SKY - Imagery, Data Analysis, and Discussions relating to Military Space
SatTrackCam Leiden (Cospar 4353) is a satellite tracking station located at Leiden, the Netherlands. The tracking focus is on classified objects - i.e. "spy satellites". With a camera, accurate positional measurements on satellites of interest are obtained in order to determine their orbits. Orbital behaviour is analysed. This blog analyses Missile tests too.
Friday, 13 January 2012
Gearing up for the Phobos-Grunt reentry
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|By the Limbourg Brothers. Public domain: From the Labors of the Months [http://en.wikipedia.org/wiki/Labors_of_the_months] section of the Trés Riches Heures of Jean, Duc du Berry [http://en.wikipedia.org/wiki/Tres_Riches_Heures_du_Duc_de_Berry]
back to good book of the day:
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BEIRUT, Lebanon — The killings have been both deliberately lurid and strangely intimate. Designed for broadcast, they have helped the Islamic State militant group build a brand of violence that shocks with its extreme brutality, yet feels as close to viewers as the family images on their smartphones.
Broadcast specifically to frighten and manipulate, the Islamic State's flamboyant violence consumes the world's attention while more familiar threats, like the Syrian government's barrel bombs, kill far more but rarely provoke global outrage.
A few human rights advocates and antigovernment activists in Syria are creating shocking if nonviolent images and videos — even herding children in orange jumpsuits into a cage — to call attention to the wider scope of violence. So far, though, their voices have hardly been heard.
The Islamic State's campaign of high-profile killings is not war at a remove, with the mechanized distance of drone strikes or carpet bombing. It is one-on-one slaughter with Hollywood production values, seeking to maximize emotional impact and propaganda value.
Cameras zoom in as captors lay hands on their captives — Western reporters, a Jordanian pilot, Egyptian Christian laborers. In the group's latest video, black-clad men lead the Egyptians almost gently, one by one, down a sunset-tinged beach, then saw off their heads until the waves turn red.
For many in the Middle East who obsessively share the latest images, the Islamic State's exhibitionist brutality is the apotheosis of several years of carnage gone viral. The group's bloody imagery, flooding social media already widely used to chronicle conflict, makes violence seem ubiquitous, even mesmerizing, and spurs a sensory overload that can both provoke feelings and numb them.
Iraqi Army Retakes Government Complex in Central Ramadi
Efforts to stem the rise of the Islamic State.
"It's like action movies," said Ahmad, 39, an employee of the Damascus Opera House in the Syrian capital, who asked to be identified by only his first name for his safety. Islamic State violence is stylized, as if in a Quentin Tarantino film, he said, in a macabre bid "to win the prestige of horror."
The killings have been answered quickly with airstrikes — from the United States, Jordan and, on Monday, from Egypt, which said it struck in Libya, where the Egyptian Copts were killed.
While the Islamic State's provocations draw pronounced reactions, however, the less-choreographed slaughter that has killed, for instance, more than 200,000 Syrians fades to the background. Those bearing the brunt of the Syrian war's spillover across the region, and humanitarian workers trying to assist, frequently express anguish that government bombings, the displacement of more than a third of the population and the gutting of the health care system do not bring similar attention — let alone dramatic action.
Of course, that is partly a matter of realpolitik. While Western governments denounce Syria's president, Bashar al-Assad, for attacks on civilians, they do not view him as a threat on the order of the Islamic State, which is encouraging followers to launch attacks in the West.
And that difference in Western perception of the two threats exists partly because shock videos work. Even in Saudi Arabia, where beheadings are the state's method of capital punishment, they are not broadcast. When images of a recent execution leaked, they created a scandal.
But the perception gap is also because the shelling of cities in Syria has become almost numbingly normal. It is as if the value of trauma and shock has undergone a hyperinflation that neuters all but the most exaggerated images of violence.
That, in turn, has pushed human rights advocates and activists to search for eye-grabbing images of their own.
Baraa Abdulrahman, an antigovernment activist in the Damascus suburb of Douma, desperate to direct the world's attention to government airstrikes that were killing scores of people, set up a scene that echoed the Islamic State video in which the caged Jordanian pilot, in an orange jumpsuit, was burned alive.
He ordered an iron cage from a blacksmith and placed it against a backdrop of collapsed buildings, and then filled it with a gaggle of neighborhood children dressed in orange. As the camera rolled, he waved a burning torch, asking why the world responded to the killing of the pilot but not to the deaths of children in Douma. Some of the children in the cage, he admitted, were frightened and cried.
"I'm very sorry to get to this point, to use the kids," said Mr. Abdulrahman, who uses a nom de guerre for security. "But this is the fact. Our kids are getting killed every day, every moment, getting under the wreckage."
Yet images of mangled children no longer get traction, he said. "These sights, people now are used to them."
Antigovernment activists are not alone in trying to compete with the war's most lurid imagery. The Syrian government has made much of a video of an insurgent ripping the organs from a slain soldier and taking a bite.
Humanitarian organizations are also seeing the power of startling videos. A group training volunteer civil defense workers has circulated a video of what it calls "the miracle baby," an infant named Mohammad who is seen being pulled from the rubble of an airstrike. Opposition groups have passed around videos from the captured cellphones of pro-government fighters and soldiers who have apparently filmed their own cruelty, like one of a militiaman stabbing an old man in the head.
The Office of the United Nations High Commissioner for Refugees widely circulated images of triplets born in a snowstorm in a refugee camp, only to lose their mother to complications from childbirth.
"There is personal tragedy of mammoth proportions happening every day by the thousands in individual lives that never get picked up by a media camera," said Ninette Kelley, the director of the refugee agency in Lebanon, where more than one million Syrians have fled.
"Refugees whose lives have been irrevocably damaged, people who die from cancers that but for the crisis would have been treated in Syria, these wounds are very real but not always as visible."
A few have even been tempted to fictionalize. Last year, for instance, a viral video of a Syrian boy saving a girl from sniper fire turned out to have been staged by a Norwegian film crew.
But while some groups want to publicize suffering in order to stop it, analysts said perpetrators like the Islamic State seek to magnify the suffering by inflicting it twice — first on the victim and then on the viewer.
"One of the things about traumatic imagery is that it can numb us and render us passive and helpless," said Gavin Rees, the Europe director for the Dart Center for Journalism and Trauma, which focuses on the issues of reporting on violence. "That is part of the gain for those who are producing these videos: They want to inspire fear and helplessness."


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Property Info
6 Bed student house Jesmond all double bedrooms of equal size with a separate lounge and dining room leading on to an open plan fitted kitchen with dishwasher, tumble dryer, washing machine and 2 fridge freezers. There are two bathrooms. The house has a decked yard area off the dinning room to the rear and is fitted with double glazing throughout, burglar alarm and comes fully furnished. 42'TV HMO compliant.
FREE WiFi
- Alarm
- Flat Screen TV
- Washer & Dryer
- Dishwasher
- WiFi
£94pppw Rent Only Available 01/08/19


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Inspired by the iconic Chesterfield style, the Harrogate range features stunning, deep button back detailing and stylish scroll arms with pleated finish. Designed with a supportive foam back, the Harrogate range boasts resilient foam filled seats with removable covers for easy cleaning and is crafted with a full zig-zag spring platform for superior comfort and support. Constructed from seasonal hardwood that has been selected from traceable and sustainable sources, this sofa is carefully crafted with all key joints securely glued, screwed and stapled for enhanced durability and is supplied with a 10-year guarantee on frame and springs. Please note: Leg colour choice is not represented in the product image. Please note: Part assembly refers to leg fitting only. Click here to view Made to Order delivery information Order up to 6 free fabric samples here Did you know, we now offer a 10 year guarantee on all Made to Order Sofas and Chairs. To find out more, please click here.
Specification: Harrogate Chesterfield 3 Seater Sofa Sherlock Ruby
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Name: Chalak Osman.
Date of born: 08-03-1969. Born in Kirkuk, Kurdistan.
The abstract oil paintings by Chalak Osman are characterized by depth, spatial functioning, belans and gradient of colors. His work exudes energy, balance and harmony. Chalak is experimenting with many different types of styles and materials. Nevertheless, his own and unique style in all his paintings are recognizable. In addition you also recognize another side of the world: a world full of color and joy.


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Better prevention can curbe significant disruption to daily life and work caused by migraine
Novartis and the European Migraine and Headache Alliance (EMHA) Wednesday presented initial findings from the largest global migraine patient study to date, involving over 11,000 people from 31 countries, reveal that migraine cuts work productivity by half, as 60% of employed respondents on average missed almost a full working week (4.6 days) due to migraine in the last month.
Migraine is a neurological disease which can vary in severity with symptoms ranging from head pain, nausea, vomiting to sensitivity to light. The My Migraine Voice study included people who had at least four migraine days per month with nearly 90% having tried at least one preventive treatment, Novartis said Wednesday.
Additionally, the My Migraine Voice study examined the impact of migraine on overall work impairment, including reduced productivity while at work (presenteeism) and work time missed due to migraine (absenteeism) using the Work Productivity and Activity Impairment (WPAI) questions. Those who had worked in the last week reported that their overall work productivity was cut by over half (53% reduction), with this figure rising to 56% for those with two or more preventive treatment failures, it was said in the press release.
Elena Ruiz de la Torre, Executive Director and Immediate Past President of European Migraine and Headache Alliance, said that, despite living with such an incapacitating condition, people living with migraine strive to be very productive but need better relief from symptoms, and support in the workplace to ensure they can achieve their full potential.
Furthermore, despite the devastating impact of migraine, employed respondents shared that although the majority of their employers (63%) knew about their migraine, only 18% offered support. Also, many said they feel judged, stigmatized or misunderstood for taking days off, illustrating the need for awareness and support in the workplace, according to the report on the study. To help combat this and empower associates living with migraine to better manage their disease, Novartis Switzerland has launched a pilot program which includes, among other services, free coaching and access to an exclusive version of the Migraine Buddy platform, developed and owned by Healint. Novartis said it is also exploring opportunities to work with other employers who are interested in supporting their associates living with migraine.
Shreeram Aradhye, Chief Medical Officer and Global Head Medical Affairs, Novartis Pharmaceuticals. "The findings from the My Migraine Voice study clearly illustrate the need for more effective treatments and a holistic management approach for people living with migraine. We are committed to providing new preventive therapies and inventive solutions, including education, telecoaching and apps, to help people with migraine overcome the challenges they may face in their lives and at work."
The findings, presented at the 60th Annual Scientific Meeting of the American Headache Society (AHS) in San Francisco.


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Discover OCOM: Virtual Seminar
Join us for an informative online version of our on-campus Admissions Seminar (Discover OCOM), in which you'll learn about our programs, curriculum, clinical opportunities, Federal Financial Aid, and admissions requirements. These "virtual" seminars are designed to meet the needs of prospective students outside the Pacific Northwest. Secure your spot by registering today.


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Shy singles men are afraid to flirt, with someone that meets them. Free online adult dating sites are ideal for single people shy. Shy singles enjoy writing more than to talk. They are shy to expose with someone. They are shy to share their happiness with friends. Online dating service is the best way to shy individual meet.
Adult Dating Sites Popularity
The main reason is that they don't have to flirt with someone. Shy single women or men can each other write in men dating sites until them fully to understand one another. This is the main reason, that an online service of DatingSimilar is booming help I to find shy individual their dream partners on the Internet.
Shy single faithfully and honestly. They are just shy. You are not unhappy. Shy single people have the feeling that they do not trust to disclose something with others single mature women. People need love than others in dating sites you want to be loved by others. Shy people may be on love and romance faithful than others. Are you one of the shy singles? You should proud on themselves and life regardless of your flaws.
We all need love. There is a strong feeling. Love and relationship are related to each other. It is difficult at some point shy individual in adult dating sites to look for a mistress. You need to change your ideas about love. I know it is hard to say "I love you" for shy people. You must try to do more, to understand others, you speak.
Dating Sites Tips
Be not afraid, speak with your partner. This Internet day helps singles really shy. They have to say not much to them through free dating sites each other. Shy single men looking women can with shy single women chat, as long as they want, until they fully know each other. Write by E-mail or in chat online dating are perfect for shy individuals.
A free dating service was created. Looking for data on net is simply too popular. Single men women seek these dating sites are completely free in recent years rapidly. No cost you can find single men and women online. Shy singles can search for relationship and marriage to this Internet dating sites.
It's great to find a true love network in women dating Online dating service is known, that all singles who know. Find your true love online. There are many single people their true soul classmates have found online.
Online dating is good. However, caution should pay shy individual. Meeting you think that you may be fit to meet personally. You must learn this single person carefully before you can arrange for a personal meeting. In particular in dating sites if you are looking for a serious relationship, caution is a must. Some online singles are higher than their real age.


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Luxembourg Sneaker
The Luxembourg Sneaker is fashioned from plain calf leather and signed with the new Louis Vuitton cursive signature on top of the iconic LV Initials. The simple shape and bold-colored leather make this comfortable sneaker a wardrobe essential. The white outsole is discreetly debossed with Monogram flowers.
Detailed features
- Plain calf leather
- Red
- Louis Vuitton script signature on the side
- Monogram flowers debossed on the outsole
- Rubber outsole
- Made in Italy
To preserve the beauty of your product, we recommend following these guidelines for its care- Clean smooth or grained leather with a soft, damp cloth. When the leather is dry, apply a quality colorless cream and polish in circular motions with a soft cloth.
- Keep your shoes in the two felt pouches provided and store them in a cool, dry, well-ventilated place.
- Avoid contact with water, any substance containing alcohol (perfumes, solvents etc.) or oil (makeup), and abrasive products in general. If shoes have been in contact with water, it is important to allow them to dry thoroughly on shoe trees cleaning them.
It is important to allow your sneakers to air naturally, and to this end they possess a removable insock. If your sneakers become wet, simply remove the insock and leave them to dry in a cool, well-ventilated place. This will ensure additional comfort when they are next worn.
Client servicesBy Telephone :
+852 8100 1182
Monday to Sunday: 11:00am - 8:00pm Hong Kong Time


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The Hoop Bike Rail is part of the range of fit for purpose Class 3 secure bicycle parking facilities and provides a convenient and economical way to park bicycles safely and securely.
The Hoop Bike Rail is designed to meet AS2890.3-1993 and AUSTROADS Guide to Traffic Engineering Practice Part 14 requirements, the rails support the whole bicycle enabling both wheels and frame to be locked with a chain, cable or D-lock.
The Arrow Alpha range of bike parking facilities are Australian made, comply with AS2890.3 guidelines and go a long way in helping building projects earn Green Star Points.