system
Given the following post, respond as if you're commenting on Reddit:
human
ELI5: what’s the science behind the difference in the nasal spiciness of horseradish/wasabi etc and the mouth spiciness of chillis?
gpt
Different chemicals.

The spiciness in chili and other peppers is caused by capsaicin, which stimulates the heat sensing receptors in your mouth. Meanwhile Wasabi and its friends have allyl isothiocyanate which triggers a different set of pain receptors.