system
Given the following post, respond as if you're commenting on Reddit:
human
What is the science behind isotretinoin commonly know as Accutane?

Just curious on how it gets rid of nodular acne. Bonus Points if you explain why the common side effects happen.
gpt
Accutane belongs to a type of medicine known as retinoids. Accutane alters DNA transcription. This decreases the output and alters the size of the sebaceous glands. It also make cells near the sebaceous glands less sticky so they don't form black heads or whiteheads. And finally it reduces the number of bacteria on your skin. 

Most of the side effects are cause by how isotretinoin, the active ingredient affects the body.