system
Given the following post, respond as if you're commenting on Reddit:
human
[DeadPool] What caused Deadpool to be able to break the fourth wall? Did his mutation drive him insane or is he genuinely aware he's in a comic?
gpt
Basically Deadpool has cancer of the [everywhere] *and* a very powerful regeneration ability.  His brain is constantly being eaten by the cancer and rebuilt by the regeneration.  As a result he's crazy.  

**However** his insanity just happens to perfectly correspond to our perception of his reality.  In-universe he thinks he's a comic book character and is wrong.  To us he thinks he's a comic book character and is correct.