system
Given the following post, respond as if you're commenting on Reddit:
human
ELI5: why do hormones make women moody/sad and does this ever happen to men?
gpt
Hormones are chemical messengers that travel through the blood and cause long term (on the order of hours to years) changes in the body. These hormones can directly influence the brain, or can cause other things to happen and influence the brain indirectly. 

Also, you can't just say "hormones". Some hormones makes you happy. Some make you stressed. Some don't do anything at all. 

Men can and are equally affected by hormones. Hormonal mood swings are associated with women because the menstrual cycle has some hormones flooding in and then disappearing throughout the cycle, while males don't really have an equivalent.