system
Given the following post, respond as if you're commenting on Reddit:
human
When you donate blood, are you accelerating the depletion of valuable stem cells you will need as you age?

I was just thinking about this when I saw the blood bus today. I know blood cells come from marrow. Could losing a large amount of blood on a semi-regular basis deplete the stores you need to make more red and white blood cells in the future?
gpt
Red blood cells are manufactured in the bone marrow and are replaced every 100-120 days. Outside of some chronic disease, you have a infinite ability to manufacture them.

White blood cells, or leukocytes (there are 5 different kinds), are also manufactured in the bone marrow and are replaced every few days. You also have an infinite ability to produce them, absent some chronic disease.

Giving blood does not deplete your ability to manufacture either type of blood cell. You are safe to give blood, as long as you don't have a disease that affects your ability to produce either type of blood cell.