system
Given the following post, respond as if you're commenting on Reddit:
human
With the talk of a functional bionic eye, would hallucinogens impact the users perception just like a real eye?
gpt
Oh yes.  The physical tools of perception (lens, retina etc) are merely the first step in the process.  Perception is highly constructive- you create what you see based on utility and past learning.  The idea of direct realism/direct perception is not well supported in the vision research world.  The way that humans perceive the world is highly specific to our species and is NOT necessarily a true representation of reality as it truly is.  Perceptual processes are heuristics for guiding behavior (i.e. finding food, avoiding death, mating, etc etc)  See Interface Theory (D. Hoffman) , Vision ( D. Marr )

Hallucinogens alter the way information is dealt with on a higher level than the eye to begin with. Any differences in the experience would be rather muted, and would be analogous to the differences in bionic/biologic sight to begin with.  A person with a bionic eye will get used to the input that it creates and that may be different from a natural eye (until bionic eyes become functionally identical).  Taking hallucinogenic drugs will alter the way that perceptual items (objects, faces etc) are processed and created in the same way that it would alter them for people with normal eyes.  

tl;dr : Hallucinogens work on the brain, the mechanics of the eye shouldn't matter much.