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human
What happens to males and females after they experience an orgasm? (Chemically, in their brains)

I did some light research, and i came up with a few things, but i wanted to ask you guys too, being a direct source - and hey, the more information, the merrier. 

From what i found, Mens levels of testosterone drops and "both genders experience similar chemical changes" - i was hoping someone here had some more specific information. 

The information i want, is that of the major chemical players. People become fatigued, hungry, content (etc) - but how long does it take for these major players to return? Which chemicals are even involved? The chemicals that both genders share, do they return as quickly for both sides? Does an estrogen loss make females tired, like testosterone does in men? 

Any (more offical) documentation/links about this idea elaborated is completely welcomed. Any rants and tangents on the subject are welcomed too, i'm very interested in the working of pre- and post- intercourse biology.
gpt
The "similar chemical changes" aren't far from what you might predict. But it's really during orgasm that the brain chemistry really goes off the rails and post-orgasm is mostly recovering from that. Mostly those changes involve a lot of relaxing sorts of things like serotonin and prolactin. Also there are hormones like oxytocin and vasopressin which are 'love' hormones that are associated with forming pair-bonds.     
But that's all mostly true for both sexes.   
I think the place you really get any difference is in how those changes will interact with the sex-specific normal conditions.   
As an example it's been suggested that in men's brains the effects of oxytocin are somehow mediated to some extent by testosterone which would help to explain why men seem sometimes better able to engage in casual sex without necessarily making any strong emotional attachment.    
Also, men tend to fall asleep after sex and hypothesized reasons for that range from prolactin to depleted glycogen.