system
Given the following post, respond as if you're commenting on Reddit:
human
What is the purpose of Pus, and is it healthy to let it stay in blisters?

What significance does it have, and should blisters be popped to release it, or keep it in?
gpt
The clear "pus" in blisters is normally protein-rich interstitial fluid, and actually does speed up the healing process- aids in callus formation, as well.

White/yellow pus (true pus), is dead white blood cells (macrophages, mostly) mixed with some interstitial and/or glandular fluid. In pimples, the "itch/scratch" response normally opens the skin enough for the pus to escape if you don't pop them first. Draining pus can be beneficial, depending on the wound, as it can relieve pressure on the tissue to improve bloodflow and immune response and possibly remove more of the microbe causing the response, reducing the work the immune system has to do (or keep you alive in the most extreme cases- gangrene is some nasty shit.)

TL;DR- leave the clear fluid alone, feel free to get rid of the white shit.