system
Given the following post, respond as if you're commenting on Reddit:
human
[HP] Can you just Avada Kedavra a horcrux?

The killing curse "strikes at the soul"  ^(or some drivel like that) and leaves the body intact. A horcrux is a soul without a body locked in an object.

So: Can you avoid all the "bathing of ancient artifacts in the venom of slain monsters" business and just AK the damn things?
gpt
Not normally. The Killing Curse separates body from soul, but a horcrux is part of a soul already separated from the body. To unmake a horcrux, it must be damaged beyond all magical repair-- however since there is no repairing death, if the horcrux is a living thing, like Nagini or like Harry himself, then yes.