system
Given the following post, respond as if you're commenting on Reddit:
human
[General] In many adventure games you can choose which skill tree/power(s) to get, often resulting in not having access to some others. Are there some examples of this in sci-fi/fantasy/mythology where a character is given a choice of abilities/powers but this will result in being denied others?

Some God, higher power, or technologically advanced being gives you a choice of say 3 out 4 powers (or something).  Choosing A and B makes you unable to choose C and D.  Something like being given nanotech based enhancements makes you unable to receive genetic enhancements, or fire-based powers denies you access to water-based powers, but not in a video game setting (just from sci-fi, fantasy, or mythology instead).
gpt
The Illiad started with Paris being offered three gifts from three goddesses in exchange for him giving them the golden apple (long story). IIRC Hera offered him the greatest kingdom in the Aegean Sea, Athena offered him to be one of the wisest of priests who ever lived, but Aphrodite offered Helen, the fairest of all beauties.

I guess if it were put in video game terms he turned down a fully developed kingdom or a crazy high permanent INT and Wisdom stat boost so he could watch the one cutscene in the game with the boobies.