system
Given the following post, respond as if you're commenting on Reddit:
human
Does drinking a large amount of water during or after a meal decrease the effectiveness of stomach acid for digestion?
gpt
Any time you increase the volume of your stomach contents, you increase the surface area on which stomach acid can "work." If it begins to work well--by digesting and emptying its contents--the chemical feedback loop inhibits further production of acid.  
  
Water itself is not a signalling factor for gastrin, which is the main chemical that induces the release of hydrochloric acid from the parietal cells of the stomach.  
  
However, there are pressure receptors in the stomach that activate when your stomach distends. So while drinking a lot of water may dilute the HCl concentration initially, the mere presence of additional volume would induce the release of more HCl shortly thereafter.

**TL;DR:** Not really.