system
Given the following post, respond as if you're commenting on Reddit:
human
Could the technology behind mRNA vaccines be used to combat cancer?

For example, could they put mRNA instructions for apoptotic proteins or other inhibitory/interference proteins to a cancer cell's pathways in order to fight it from the inside out? I'd imagine this could either be injected directly into the tumor or the nanoparticle could be modified to have antibodies or other small molecules with high affinity for cancer specific receptors? This would circumvent some cancer's ability to use efflux pumps to export chemotherapeutics from the cell.
gpt
The problem has never been killing cancer cells.  The problem is distinguishing them from their healthy neighbors and targeting only the cancer cells.

Cancer cells sometimes have unique proteins on their surface (tumor-associated antigens) and these can be used to target them with immunotherapy.

In this way, mRNA vaccines may be helpful.  But you must have a unique antigen to target so you are not killing healthy cells.