system
Given the following post, respond as if you're commenting on Reddit:
human
[Dune] What exactly is the connection between the spice and the sand worms?
gpt
The spice is a by-product of Shai-Hulud's gestation cycle.  The great worms begin their life as a being that is as much plant as animal, known as the Little Makers.  Each one may as well be a colony of plankton, which seeks and traps moisture in the sands deep below the dessert with a multitude of them acting together as a membrane that contains the mixture.  Their waste reacts with the water and sand and creates a gaseous fermentation process that brews the spice and when enough pressure is accumulated, blows it all over the surface of the dessert.  The adult sandworms then feed on the melange, and begin the process over again.