system
Given the following post, respond as if you're commenting on Reddit:
human
[MCU] Is the MCU a whole reality apart from the comics?

In the first episode of the Loki series we learn that the TVA's purpose is to prevent a multiverse from happening by making every possible timeline follow the exact same events. This immediately discards the idea that Earth-616 and Earth-199999 (MCU) can exist in the same multiverse.

Does this mean that what we see in the MCU completely deviates from the multiverse that exists in the comics and leads to two completely different and unrelated realities to exist? Or could this show see the creation of the multiverse and is, instead, a prelude of everything that happens in the comics?

The problem with the second theory is that there still exists a TVA in the comics which purpose deviates a lot from the series one.
gpt
The TVA is not a trustworthy organization, so you can't exactly take their word for it that the timekeeper story is true. There may not even be timekeepers.

But even if the story is true, there was a multiverse that existed before the MCU. The multiverse war referenced sounds a lot like Secret Wars from the comics. If the story is true, the Marvel multiverse may be something that predates the MCU, before the development of the sacred timeline.

A key feature of the Marvel multiverse is that it has cycles where it us creates and destroyed. There have been eight incarnations of the multiverse in comics so far. The MCU may be the ninth.