system
Given the following post, respond as if you're commenting on Reddit:
human
[Dune] How exactly was Baron Harkonnen able to break Yueh's imperial conditioning?

Dr. Yueh's conditioning was a big deal in the book and many are shocked that it was able to be broken.  If its such a strong guarantee of loyalty, how was the simple act of kidnapping his wife able to break it?  I've read the book multiple times and this was never clear to me.
gpt
It's not detailed in Dune, but later novels expand on it.  Dr Yueh was  married to a Bene Gesrerit sister, who was abducted by the Harkonnens.  As the Harkonenes are famous for their torture of their hostages, making this is particularly horrifying prospect.  The sisterhood have also mastered sexual conditioning, which appears to have been stronger than the imperial conditioning in this case.  Apparently the Harkonenen mentat used this cleverly to leverage to blackmail Yueh into his betrayal.