system
Given the following post, respond as if you're commenting on Reddit:
human
We know about viruses, bacteria and other microorganisms evolving to better infect other organisms. Consequently, diseases change too to some extent. Are there any examples of human bodies evolving to fight against these disease causing agents?

I don’t mean gaining immunity to diseases. I’m more interested in knowing about evolutionary changes that can pass through our genes or changes in the physical structure of organs, tissues, cells, etc.
gpt
You better believe it! The textbook case for this is the "sickle cell" trait. This is the gene that causes sickle cell anemia, a horrible genetic disease where your red blood cells are all jacked up and you mostly die a slow painful death. So why is this gene still hanging around humans' genomes if it kills people? If you are merely a carrier of the gene or have "sickle cell trait", it provides substantial protection against death from malaria (and the symptoms are much milder than full-blown sickle cell anemia). ~~It makes your red blood cells far more resistant to being infected by the disease-causing agent, the plasmodia~~  The crossed-out text was somewhat recently debunked, it looks like the plasmodia either struggles to survive in the mutant red blood cells, or the infected red blood cell is more efficiently removed from the body before it bursts with a payload of new plasmodia.