system
Given the following post, respond as if you're commenting on Reddit:
human
Does Horseshoe Crab Blue-Blood used in Medicine contain allergens of Shellfish for those with allergies?

Hi everyone,

I came across a post about Horseshoe Crabs and how we leverage their blood (limulus amebocyte lysate) for use in the medicine field.

I have an extremely severe shellfish allergy - would I be allergic to those amebocyte's that are separated when used in FDA testing?

I am not sure if they are present in the actual administered injections, but I was wondering.
gpt
I've done LAL testing in the past and its not used as an administered injection into the body.

Instead, a *sample* of a substance being tested has LAL added to it and if agglutination is detected, endotoxin is present within the sample. The actual concentration is compared to a standard curve made from a diluted E coli solution.