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human
[Dune] How would events have played out if Paul was born female?

Lady Jessica was ordered to bear only girls to Duke Leto, with a view to future marriage into House Harkonnen.  How would the events of Dune have gone if she had obeyed?  Presumably the emperor would still have set his trap for House Atriedes on Arrakkis.
gpt
An interesting question.  There are many possibilities:

If the Reverend Mother was telling the truth that she wanted a marriage and alliance between Harkonnen and Atreides, then the Bene Gesserit may have "encouraged" the emperor not to go through with his trap.

Alternatively, Lady Atreides may have been taken away from Caladan to a Bene Gesserit school, keeping her safe from the Arrakis trap.  From there she could have been married to Feyd-Rautha Harkonnen as an offering to stop the slaughter of House Atreides.  Or the Bene Gesserit could have let the slaughter continue and kept her theirs, house-less.  She could then seduce Feyd-Rautha some time later.  Marriage was not required to conceive the Kwisatz Haderach, only one night of drunken passion with a "nameless girl".

Of course, it's entirely possible that Lady Atreides might have failed the test of the gom jabbar.  Part of what allowed Paul Atreides to pass was the Mentat training he'd been given from Thufir Hawat.  An Atreides daughter may not have recieved the same training.

If Lady Atreides did go to Arrakis with her family and fall into the trap, her first interactions with the Fremen would have gone differently.  She would likely have ended up a wife of Stilgar or even Jamis.  From there she could possibly have led (either overtly or from the shadows) the rebellion against Beast Rabban.  But without the same abilities of foresight that Paul had, it's unclear how successful that rebellion would have been.

Still, the Baron Harkonnen was setting Beast Rabban up for failure against the rebellion, in order to be replaced by the savior of the people, Feyd-Rautha.  So it's *also* possible that the Lady Atreides could have wed him, ending the Fremen rebellion and fulfilling both the Baron's and the Bene Gesserit's original plans.