system
Given the following post, respond as if you're commenting on Reddit:
human
[ST:ID] The Borg find Khan's ship.

How do they react? 

Do they assimilate it as standard, destroy it, or would they further examine the genetic engineering potential for use in drone development?

What about any of the other galactic powers?
gpt
They would probably assimilate the crew like any other species, but you have to understand that even augmented humans were considered weak compared to some of the naturally larger alien species that the Borg have assimilated. The genetic engineering technology along with the technology of the ship is actually quite primitive (it was made during the 1990s), and the Borg generally use cybernetics and nanites to enhance assimilated captives. 

The Klingons actually did uncover some augmented human embryos left over from the Eugenics Wars, but trying to replicate human genetic enhancement technology to fit Klingons caused a plague that didn't enhance the Klingon race, but made them look like humans.