system
Given the following post, respond as if you're commenting on Reddit:
human
Why is taking hormones not more common?

I read another thread here that mentioned estrogen and how it affected body shape etc. Transgender people seem okay taking what I imagine is large amounts of hormones? Why is it not normal for people to supplement, especially as they get older and have lower testosterone and estrogen levels.
gpt
Need to be careful. Giving someone estrogen on its own will increase risk of uterine cancer (and breast cancer potentially). People do often use hormone replacement therapy after menopause which is a combination of estrogen and progesterone.