system
Given the following post, respond as if you're commenting on Reddit:
human
[Spider-Man] Are there any villains from Spider-Man's rogue gallery that he doesn't fuck around with, like, if he's up against one of them he's not cracking jokes or anything, he actively wants to stop them ASAP?

I know a characteristic of Peter as Spider-man is to crack jokes or mess around with his opponents. Only when things get serious like a family member is in trouble is Peter really into stopping the baddie and no wasting his time goofing off.

But is there anyone that when they get loose on the city, Spider-man isn't kidding around with? Basically, who is the one who makes Spidey shut up and take them as a serious threat every time they come across each other?
gpt
The cracking jokes is a combat tactic in a very real way - it's not indicative of "messing around" or "toying with" with his opponents, it's a viable strategy for him. Spider-sense lets him unconsciously dodge pretty much everything, so he can focus on irritating and infuriating whoever it is into overextending and making a mistake, because as superheroes go, spider-man isn't actually that high-tier in a 1v1 knock-down-drag-out fight - he doesn't "mess around" because he isn't taking it seriously, he "messes around" because he so often fights enemies orders of magnitude stronger than himself and that's the only safe way to fight them. So to answer your question...

Any kind of robot or monster that doesn't speak English.

If whoever it is has managed to traumatize Peter past the point of being able to make jokes(Like certain incarnations of the Green Goblin).