system
Given the following post, respond as if you're commenting on Reddit:
human
[Vampire the Masquerade]In the Middle ages vampire kind in Europe seriously considered making war on humans due to the rising risk that they posed. Instead they implemented the masquerade. Supposing that they did go to war and try to enslave mankind, was there any reasonable likelihood of success?

instead they made the Camarilla. Would they have stood any chance at all if they try to take over mankind?
gpt
Highly unlikely, hence the implementation of the masquerade to begin with.

Keep in mind that vampires aren't the only supernatural force in the world, and many of the other things going bump in the night are perfectly capable of killing kindred, particularly the higher generations. 

Open war would ruffle enough feathers that many kindred would meet their end at the hands of a werewolf pack, or by magical flame. It may also cause a marked increase in the number of humans with True Faith, presenting problems of their own.