system
Given the following post, respond as if you're commenting on Reddit:
human
How do people die from burns?

How does somebody die from large burn wounds if they are still internally sound? I'm wondering what the actual mechanism is e.g. blood loss, shock, etc.
gpt
Skin represents the major barrier to infection and disease across the body.  Compromising that barrier opens the patient up to opportunistic infection across the entire wounded surface.  Additionally, skin prevents water loss, and given a large enough surface area, dehydration can become a serious consequence.