system
Given the following post, respond as if you're commenting on Reddit:
human
ELI5: Can humans accept blood donations from other species? Why or why not?
gpt
Generally speaking, no. Your body will detect proteins in the other blood as foreign agents and create antibodies to kill it, and that kind of reaction can be fatal.

I mean look at just human blood. We can't even accept blood from specific blood groups based on our own blood type. Adding in the foreign proteins of animals would be a nightmare.