system
Given the following post, respond as if you're commenting on Reddit:
human
Since our bodies can eradicate cancer cells to an extent, why can't we drastically mutate the antibodies that kill the cancer cells for people who have cancer? Or will it create a risk to autoimmune diseases?
gpt
It's not just antibodies that are required to kill a cell. In order to eliminate cancer, the body needs a strong T cell response, amongst other things. As the other poster mentioned, CAR T cell therapy involves taking T cells from a patient, transforming them to have a cancer specific receptor, and then returning the cells to the patient. There are other strategies that are being studied, like cancer vaccines, to generate specific, strong immune responses against the tumor.

However, having something that will target the cancer is only part of the battle. Many of these therapies have shown limited efficacy against solid tumors. The reason is that it is hard to infiltrate the tumor and the microenvironment around the tumor is typically anti-inflammatory, essentially turning off cells that come to kill the tumor.