system
Given the following post, respond as if you're commenting on Reddit:
human
Will the antibodies from a blood donor attach to the antigens of the donation recipient?

I know that O- is the universal donor and that AB+ is the universal recipient because O- lacks major antigen groups while AB+ has the 3 major antigen groups.

However, what still confuses me is why the antibodies received from the donor don't attach to the recipient's own blood cells. For example, if an O- person donates blood to an AB+ person, won't the antibodies from the O- donor attach to the RBCs of the AB+ recipient?

Is this just a volume issue? Are there just not a large amount of antibodies present to attach to the recipient's cells?

Thanks for any and all responses!
gpt
Blood group O is an universal blood donor, because as you point out, neither A,B or AB have antibodies towards O (because O is the base glycoprotein).

But as you've pointed out, those who have blood group O have antibodies against A,B and AB.

What you've missed is the fact that when you receive blood from a donor it's "only" the erytrocytes that you receive, the erytrocytes have been separated from the plasma and thus separated from antibodies. 
This also means that AB is the universal plasma donor!