system
Given the following post, respond as if you're commenting on Reddit:
human
Why can we freeze embryos for IVF but not adult humans? What makes it possible for embryos?
gpt
Hello! Not an expert in freezing and thawing live specimen but well practiced in freezing and thawing dead specimen while keeping organs and microstructures intact. The major concern with freezing biological matter is the formation of ice crystals. Water forms crystals and expands when frozen and can result in burst cells and organelles. To avoid this, we introduce cryoprotectants. These are basically antifreeze that diffuse into the cells and around it to avoid formation of crystals. It's very easy to diffuse these new compounds into microscopic specimen because the surface area to volume ratio is very high compared to humans. Very rapid freezing with liquid nitrogen, also known as flash freezing, also helps in avoiding formation of large crystals (slow freezing means more time for the molecules to align). So the simple answer is size. We can't introduce cryoprotectants into every part of a human being fast enough nor can we flash freeze a human body fast enough.