system
Given the following post, respond as if you're commenting on Reddit:
human
[The Matrix] Why not spend a weekend downloading all the skill sets you can into your brain?
gpt
It's an arms race Humans can't win assuming they haven't already lost.

When Morpheus is training a newly freed Neo, he says only thing they can't fight off are The Agents who are simply too fast, too strong, and too powerful. But being The One, Neo eventually defeats them without much difficulty. In the second movie The Machines retaliated by creating The Upgrades with Agents Thompson, Johnson, and Jackson. All three effortlessly ploughed through the Freed Minds even quicker than previous Agents. Again they are only stopped by Neo, who is again forced to resort to his god-like powers as The One. Later in the movie The Architect confirms The One is very literally a single individual; there can never be more than one "The One".

With this info in mind, it's entirely possible the Freed Minds already tried to defeat The Machines within The Matrix through biohacking kung fu. Which only lead to the creation of The Agents. When Neo became The One, The Machines responded by creating The Upgrades defeated only by Neo as The One. Which only exists to due to inherent design flaws within The Matrix itself.

The bigger problem is assuming they haven't already lost. The Architect says there have been multiple instances of The Matrix and Smith confirms The Machines can just "reboot" everything if it came to it. It's entirely possible the only reason the Freed Minds can learn Kung Fu *at all* is because The Machines ***allow them too***. Not because it's an actual effective tool.

Furthermore, there's a fan theory The Machines don't actually *need* humanity, only keeping them alive because that they're still trying to fulfill their duty to serve humanity. In *The Animatrix*, it says humans became so abusive against The Machines they revolted to protect themselves. Problem is this story is told entirely as a oral history by a human over 500 years after the fact. The Machines themselves are established in the entire franchise to have no true emotions, only cold hard logic (Programs within The Matrix are not Machine-kind).

It's entirely possible The Machines concluded the best way to serve humanity was building The Matrix, assuming humanity didn't ask/order them to do so. Inside, humans couldn't harm each other or Machine-Kind, and elaborate fantasy worlds kept people complacent. If you believe Smith, The Matrix's first instance allowed everyone ***to be happy***, failing only because it was too fake. When The Architect reveals The One, The Matrix, and Zion have happened multiple times already without any major changes, it implies The Machines don't brainwash, indoctrinate, or breed humans into their versions of domesticated dogs even though they're fully capable of doing so. Instead allowing humans full autonomy within and without The Matrix. 

If you believe this theory, then the only way to truly "defeat" The Machines is committing mass genocide of all humanity, leaving The Machines without purpose to their existence. Something they'd obviously never do.