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human
[Bioshock] why do some people become sploicers while our protagonists do not (possible spoilers)

It seems that all of Rapture, and some of Columbia is plagued with sploicers, while the protagonists, in all the games is not affected. Jack/Delta doesn't show any adverse affects, neater does Booker or Elizabeth. Each of these protagonists, take massive amounts of adam/vigors. Also most sploicers seem to only have one ability, while our protagonists has many. By the end of the game our protagonist should be really messed up!
gpt
*Splicers. 

Anyway, becoming disfigured is an effect of long therm ADAM abuse. Jack and Delta wasn't users for very long, and since both left Rapture, they basically had to go cold turkey, getting over the addiction.

Anyway, we don't see their faces at the endings, so they could still be disfigured.