system
Given the following post, respond as if you're commenting on Reddit:
human
[MCU] From what we've seen of both Thanos and vibranium, IF they had somehow managed to physically cage and detain him entirely with things like heavy-grade vibranium cages, shackles, and anything else, could you have held Thanos indefinitely as a prisoner?
gpt
Vibranium isn't indestructible in the MCU; Thanos' own sword was able to cut through Cap's shield, the Black Order had weapons that could harm the Vision's organic-vibranium weave, and Wakanda has sonic devices that nullify its properties entirely. 

Add in Ebony Maw's telekinesis, and the fact that there are Sorcerers in the universe using sigil magic very similar to Kamar Taj, and the chances that *someone* would break him out is nearly 100%.

Thanos wouldn't have been able to escape vibranium shackles by himself, but Thanos himself was never the real danger: it was the cult of fanatics that were willing to destroy worlds or lay down their lives in order to help him achieve his goal.