system
Given the following post, respond as if you're commenting on Reddit:
human
Can you develop Autoantibodies against your own Blood group antigens?
gpt
Yes.  Most times, they are not clinically significant but rare fatal cases occur.

Google cold autoagglutinins.  There is lots of knowledge about this because they were originally detected in a hospital setting in the lab once an order for Type and Crossmatch was received.