system
Given the following post, respond as if you're commenting on Reddit:
human
[Harry Potter] Could Voldemort's Snake, Nagini, be killed with a regular (non-horcrux-killing) weapon?
gpt
Short answer- we don't know.

Long answer- it could be any of a few possibilities.

1) Nagini is magically protected. If the horcrux is altered physically, it reverts itself, or can't be changed at all. This is unlikely, as the diary could be changed (written in, possibly have pages torn from). Nagini also probably still sheds skin, defecates, etc, so the problem becomes- where does the horcrux end? Parting the horcrux's matter is a really annoying thing to think about.

2)Nagini dies, and the horcrux is released. Lacking the container, the soul is released, destroying the horcrux. This is also unlikely, as this could happen by means that could normally not destroy a horcrux. Nagini dies of old age? Horcrux lost. Nagini's death is too easy to come by, for an immortal soul container.

3) and the most likely, IMHO, is that Nagini dies, but the soul is still contained in Nagini's body. Nagini would still leave behind a physical corpse, meaning a container still exists for the horcrux. The corpse would need to be destroyed by permanent magical means to release the soul, such as magic sword, magic fire, or magic snake venom. 

Tl;Dr- Likely the soul persists in the snake corpse after death.