system
Given the following post, respond as if you're commenting on Reddit:
human
ELI5 - why do antidepressants make it more difficult to reach orgasm for some?
gpt
Antidepressants affect how nerves send signals to each other. An orgasm occurs when nerves linked to the genitals send signals to the brain that the brain interprets as pleasureable, with sufficient strength and over a sufficient period of time for the brain to figure that sex is well under way and now would be a good time to finish up. The exact arrangement of communications here is very complicated, but the basic gist is that antidepressants, which affect how nerves communicate, makes it harder for this system to reach the brain's predetermined level of sufficient stimulation.