system
Given the following post, respond as if you're commenting on Reddit:
human
ELI5: Can people actually be "Driven insane" or is that just something that happens in the movies?
gpt
Absolutely.  This is a "nature vs. nurture" question and circumstances can absolutely bring on serious mental health issues.  Severe PTSD is an example, you can certainly use drugs to induce insanity - both "while under the influence" and lasting.  The correlation between childhood trauma and various forms of mental illness, including schizophrenia and psychosis is high.  This is not to say that genetics doesn't play a significant part, but...yes, at least some people can be brought to insanity through experience.