system
Given the following post, respond as if you're commenting on Reddit:
human
eli5: Does Manuka honey really have effective anti bacterial properties? Why does bacteria not build resistance from it if it's consumed daily?
gpt
All honey is anti-bacterial, not just Manuka honey.

There's no evolved resistance because of the *way* it's anti-bacterial. Honey has so much sugar in it that it sucks all the water out of bacteria it touches, killing them. You can't "evolve resistance" to that the same way they can't evolve resistance to a blowtorch or humans can't evolve resistance to lava. The mechanism is "complete annihilation", no possible body change will up the chance of survival, so none evolves.