system
Given the following post, respond as if you're commenting on Reddit:
human
Can other species get Down syndrome/trisomy 21?

Some species don’t have 21 pairs of chromosomes but can they get a Down syndrome like disorder ?
gpt
Due to the differences in the genomes, there is no direct equivalent to Down syndrome in animals, but they can get trisomies. One example is trisomy 28 in cattle, which is usually fatal shortly after birth or during gestation. Another example is trisomy 16 in mice, which is used as a limited model for human trisomy 21.