system
Given the following post, respond as if you're commenting on Reddit:
human
What happens at a biochemical level to cause problems when a fever runs too high?

As a layperson, it seems sort of unbelievable that the reactions critical to human life could be optimal at 98.6 F, but be so far off base by 104F-106F that death is a possibility.  Can someone give some specific examples of why cells begin to die when a fever runs that high?
gpt
Eggs are mostly protein. When you cook an egg, do you notice how the white part of an egg is originally colorless and see through? Then after the egg reaches a certain temperature, the color turns white and it solidifies? Those physical changes occur because the protein has denatured. That is similar to what happens to your body and brain tissue when you run a very high fever. Although instead of getting a healthy meal, you die.