system
Given the following post, respond as if you're commenting on Reddit:
human
Does Neosporin and other topical antibioitics breed anti-biotic resistance?
gpt
The antibiotics in Neosporin and similar ointments use classes of antibiotics that are almost never used as injected or oral drugs. Resistance may develop to the topical drugs, but there is virtually no effect on the effectiveness of systemic drugs.

In many ways, the topicals may decrease antibiotic resistance by preventing superficial infections from getting worse and requiring systemic drugs.