system
Given the following post, respond as if you're commenting on Reddit:
human
[Halo/the Culture] Could the Logic Plague affect a Mind?

Since the Logic Plague is said to be adaptable?
gpt
It would depend on the circumstances surrounding how the Mind came in contact with it. 

The Logic Plague is adaptable in the sense that it can vary its approach, but the endpoint is always the same: to induce rampancy by revealing the truth of an AI's existence backed up by verifiable information pulled from a data system built into the structure of space-time itself. 

A Mind is an intelligence built from fundamentally different engineering principles than a Halo ancilla; they're thousands of years past the point where they'd have to worry about something like rampancy. A Mind is also not easily given to existential angst about its ultimate purpose. If a Mind ever got the point where it felt like nothing it did mattered, they could always Sublime. 

If the Mind encountered the Logic Plague within the Halo Universe they might be convinced to go along with the Flood on the grounds that the fundamental structure of the Universe does seem to support their viewpoint (and so that they can subtly influence the Flood into a more Culture-like respect for individual organic life). 

Outside the Halo Universe, the Mind would dismiss it as Homogenizing Swarm sophistry and go back to simulating planets where the dominant forms of life are sentient squirrels for fun.