system
Given the following post, respond as if you're commenting on Reddit:
human
[X-Men] How can adamantium be poisoning Wolverine if it's indestructible?

This never made sense to me; the adamantium 'poisoning' Wolverine.  That would mean some part of the metal is breaking down and entering his bloodstream.  But if it really is indestructible then how can it be breaking down?
gpt
It could be damaging his blood cells as they exit his bone marrow, we know it's porous enough to let them through, but perhaps not the right shape, or the opening is just a little small.

It also could be altering the pH of his blood significantly

It could be a catalyst (or an inhibitor).

It could be just the right shape for other bacteria to attach too, and so he could be growing all sorts of sepsis on his skeleton.