system
Given the following post, respond as if you're commenting on Reddit:
human
[Star Trek] How do the Borg handle non-humanoid races?

How would they have assimilated or otherwise dealt with the Founders?  The Calamarain?  The Prophets?

Bonus question: How would they have dealt with all of those BEFORE they got the nanoprobe technology?
gpt
The Borg are probably researching assimilation techniques for all types of life 24/7, almost like a background program in the collective. It's just that it's incredibly difficult and not nearly enough information has been gathered to make a trial run.