system
Given the following post, respond as if you're commenting on Reddit:
human
[Bioshock 1&2] are there no sane humans left?

Aside from the couple of allies and enemies you talk with on the radio, you never meet an npc you can talk with, only completely deranged splicers and brainwashed big daddies and little sisters.  
Where did those who didn't splice and those who only spliced a little go? Why doesn't the protagonist lose his mind too? Did the sane people escape in time if they had money? Did everyone get killed, despite the fact that splicers are so insane that they have very little mental faculties and have no plans? How did rich people die if security bots and armed camera turrets exist?
gpt
No, nobody sane is left in Rapture.  The thing of it is this wasn't a single event that caused everything to go to hell, it was a slow gradual decline into dystopia.  

This means that the sane people who had the vision to know what was coming bugged out fairly early.  Those who stayed got gradually more and more used to the kind of horrors happening in Rapture.  By the time it got really bad, there is no such thing as a Rapture citizen who only splices a little.