system
Given the following post, respond as if you're commenting on Reddit:
human
ELI5: Why is it that when we eat something too much we start to dislike it?
gpt
We have an innate desire of a healthy, varied diet with lots of different nutrients, vitamins, etc., to keep our bodies supplied with all the items required by our metabolism.

Short term, this means that when you eat a whole lot of a single meal in a short amount of time, say a lot of candy, your body is giving a response that it's had enough of that nurtrient, and is likely reaching unhealthy levels where it will have to waste resources instead of use it.

Long term, it's a bit more psychological. Our desire to try out new recipes, new foods and change from the old ones is, when you have a steady and healthy diet, likely because you have acces to information about new food: such as new recipes, new information about certain nutrients, cooking shows, advertisments, etc. I'd argue that the desire to experience a new and exciting flavour eventually causes a mental link to dislike the food you're used to.

Extremly long term, the bud tastes on your tongue, like all other cells in your body, die off and are replaced with new cells. This means that roughly every few years you develop a slightly altered taste that can alter your preferences. Spicy food also scars your tasting buds that can also alter your taste!