system
Given the following post, respond as if you're commenting on Reddit:
human
[Marvel Comics] If adamantium is poisonous how does Bullseye have his whole skeleton cased in it without a healing factor?
gpt
There's a difference here. First, Wolverine's skeleton is bonded to the adamantium perfectly. It even created a new form of adamantium that acts nearly organic, allowing the blood to flow from his marrow into his body. A solid coating wouldn't allow that, meaning that he'd have no new blood in his system. But the important thing is that his bones still act like bones, and one of the most important things your skeleton does is that the marrow inside *creates blood cells*.

Bullseye, on the other hand, had a few bones *destroyed*, and then replaced by adamantium. There's no blood coming from them, they're purely there to support his body. So not only does he have less adamantium, he also isn't pushing blood through this poisonous layer of metal.