system
Given the following post, respond as if you're commenting on Reddit:
human
What lifeform has the shortest genetic sequence?
gpt
It depends.

The organism with the smallest genome for naturally occurring cellular organisms is probably *Mycoplasma genitalium*. 

There are synthetic cells that have a smaller genome, but these are lab-made, not free-living. 

Then there are viruses; are they life forms ? That’s another debate. If you include viruses, then *Circovirus* probably has the smallest genome. 

Pushing it to the extreme, you’d have viroid “genomes”, which are only a couple hundreds nucleotides, but that might be really pushing the definition of what a life form is.