system
Given the following post, respond as if you're commenting on Reddit:
human
If alcohol damages our livers, why does our alcohol tolerance increase?
gpt
The liver does have some specific cellular alcoho tolerance effects, but the liver is not the primary place that tolerance occurs. Keep in mind that alcohol is not a drug with acute cellular/neuronal action. It is readily absorbed throughout the body. 

Tolerance to alcohol occurs at the molecular level at many places in the body. This involves lots of mechanisms including changing the activity of chanel protein production, interacting with membrane lipids, interacting with auxiliary proteins, modulation of membrane protein expression, and altering the spatial organization of membrane proteins.  Also, we don't really understand how any of the mechanisms listed above specifically affect alcohol intoxication behaviorally.