system
Given the following post, respond as if you're commenting on Reddit:
human
ELI5: Why is it usually recommended not to take medicine on an empty stomach?

(Sorry if I used the wrong flair, didn't know whether this was a biology question or a chemistry one)
gpt
Some medicines require that you take medicine after a meal as the medicine may cause nausea or stomach irratation when taken on an empty stomach.

Some medicines require the opposite, that they be taken on an empty stomach and this may be due to precise dosage affected by food or vitamins/chemicals in the food reacting with the medicine.