system
Given the following post, respond as if you're commenting on Reddit:
human
Does the human immune system weaken in the short term if you are not around the normal minor viruses and bacteria of other humans?

On a recent episode of the Joe Rogan Experience podcast, Bro Scientist Joe Rogan theorized that the lockdown is weakening immune systems by instituting Social Distancing due to essentially "not exercising" the immune system, and could potential make Covid-19 infections worse.  What do we have for research that would dispute/confirm this?
gpt
None. If a person managed to isolate themselves for a couple of...decades, really, then yes, they might have a slightly weaker immune system than the average joe on the street, assuming everything else is the same. Your body is dealing with bacteria and viruses on a continuous basis, all the time. They're on your skin, in your hair, in your lungs and blood. If you shut down your immune system, through drugs or stress, then it can become weaker, and infection becomes much more likely and dangerous, but not necessarily because of exposure to new pathogens.