system
Given the following post, respond as if you're commenting on Reddit:
human
I'm 0 negative blood type. Could I give blood directly from my circulatory system to any other person's?

Let's say I'm a witness of an accident and I have the equipment and formation needed to do a blood transfusion directly from me to the victim. Would it be safe to do so? In other words; does my blood need to be processed in some way before being given to other person?

(Sorry for my English, I'm not a native speaker)
gpt
If you are witnessing an acute trauma, then no, you should not if you can help it, as there are better first-responder options, such as packed RBCs or IV saline. Being O- means that you have circulating plasma antibodies against other antigens. There are have been document cases of hemolytic reactions occurring several days after the transfusions, but this is *different* from the acute hemolytic anemia that occurs in ABO incompatibility, which occurs several hours after transfusion.

When considering plasma transfusion instead of red blood cell transfusions, AB+ donors become the *best* donors (because they will not create antibodies to the other antigens) and O- donors are the *worst*.