system
Given the following post, respond as if you're commenting on Reddit:
human
My chi-square analysis indicates a significant association but my logistic regression indicates no significant association. What does this mean?

I’m fairly new to statistics so I apologize if this is an easy answer.  Right now, I’m just playing with some public health data.  

I have a dichotomous exposure and a dichotomous outcome.  

My chi square analysis indicates statistical significance between the exposure and outcome.  

When I run a logistic regression in R, the adjusted odds ratio is 1.2 but the p value is 0.059 which indicates it is not significant.  In the logistic regression, I controlled for 5 other variables (two of which have a p value of less than 0.001).  

What does this mean?  Should I not be comparing chi square outcome with logistic regression outcome? 

Thank you!
gpt
You did different analyses. You shouldn't expect the same result.

If controlling for variables didn't change the p-value, you wouldn't do it.

&#x200B;

Run a logistic regression in R, without the control variables and you should get the same result.