system
Given the following post, respond as if you're commenting on Reddit:
human
[Adamantium] How to destroy it.

How can Adamantium be destroyed? What happens if it comes into contact with antimatter?
gpt
Reality warping is always a good way to get rid of it, and matter manipulation should do the trick, too, depending on the strength of the matter manipulator. 

If adamantium were to come into direct contact with antimatter, it should be annihilated just like anything else - antimatter would straight-out cancel the matter that made it up, which isn't really something that can be stopped by physical toughness. If it was just caught in the blast of an antimatter explosion, though, it should be fine.