system
Given the following post, respond as if you're commenting on Reddit:
human
How (un)healthy is it for one to work nightshift?

I used to work a few weeks of nightshift at a time and always wondered what psychological and physiological affects it has on ones body?
gpt
Working night shifts has the many negative affects on the body. It changes gene expression, protein levels including hormone levels in many organs, including the heart. The processes that happen in your body at night and during the daytime are very different. During the day you are more active, need to eat, etc, this includes higher blood pressure and heart rate during the day, but when activity levels are low during the night the heart rate and blood pressure decrease. By staying awake during the dark, you are forcing your organs to work harder when they are used to working lower, and they aren't particularly flexible in that way. Eventually, cardiovascular diseases develop as well as depression. This field is termed circadian rhythms.