system
Given the following post, respond as if you're commenting on Reddit:
human
[Hitman] Why does anyone try to make an enemy of Agent 47?

Seriously, there are lots of people, including (SPOILERS AHEAD) plenty of people in the ICA who have tried and failed to kill Agent 47. Considering that he is not only well-known as the ICA's best asset and top assassin, but is also regarded as a legend across the globe who never fails a contract, why does anyone think that they'll ever succeed against him?
gpt
Because at the end of the day he is only human.  An exceptionally skilled, intelligent, and fit human, yes, but still only human.  The ICA, the Franchise, and other underworld elements tend not to be the type to invent bogeymen for themselves to fear.  If Agent 47 represents a thorn in their side, then they're going to eliminate him. The fact that they haven't succeeded so far does not mean, to them, that 47 is some sort of superhuman ubermensch, it just means he's been lucky enough to survive, and they just need to try again.  

It's probably also worth pointing out that Agent 47 has come very close to death a few times.  He was ambushed and shot after the opera house mission in Paris, and nearly died from his wound. He was also nearly cremated alive by Alexander Leland Cayne, and was only saved by the timely intervention of Diana.