system
Given the following post, respond as if you're commenting on Reddit:
human
Are there very efficient and higly used drugs that we have no idea how do they work?
gpt
There are very many FDA-approved prescription drugs that are used regularly but for which we do not know the exact mechanism of action. A good example of this would be Lithium, a mood-stabilizer which is effective in treating bipolar disorder and schizoaffective disorders. In the case of lithium, we know that the lithium ion, administered as various lithium salts (lithium carbonate, lithium citrate), alters neuronal sodium transport but further than that, the exact pharmacological mechanism by which it exerts its mood-stabilizing effects remains unknown.