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Garlic and its potential for prevention of colorectal cancer and other conditions

Introduction Garlic (Allium sativum) has been used medicinally for over 5000 years, but in the last 30 years, a considerable body of evidence has sought to link extracts of the vegetable or its active ingredients to physiological processes and to a role in the prevention or management of human disease. Claims have been and are being made for a role of garlic in antibacterial, antiviral, antiinflammatory, and antineoplastic activities. Moreover, some evidence exists that it may prevent colorectal tumor formation, reduce cholesterol, reduce blood pressure (BP), provide anticoagulation, and provide broad antioxidant activity to limit free radical damage.