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Attachment of prostheses to the musculoskeletal system by tissue ingrowth and mechanical interlocking.

The concept of tissue ingrowth into porous biomaterials as a means of attaching prostheses to the musculo-skeletal system is reviewed. A compilation of the various ceramic materials studied in vivo to date along with the results of the studies is presented. Results of studies on kinetics of tissue ingrowth into porous biomaterials are summarized. A discussion of the parameters controlling the rate of tissue ingrowth into porous implants is presented.