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Flail Mitral Valve after Receiving Sovaldi (Sofosbuvir) for Chronic Hepatitis C Genotype 4 Infection: Case Report

A 50 years old male worker, heavy smoker and hypertensive presented by shortness of breath and palpitation. The condition started 2 weeks ago with sudden onset and progressive course. The patient gives a history of chronic hepatitis C genotype 4 which was treated by Sovaldi (Sofosbuvir), Ribavirin and Pegylated interferon alfa for the last 12 weeks. The baseline echocardiography (before starting the regimen) showed mitral valve prolapse with moderate mitral regurgitation.