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Diffusion Magnetic Imaging Applied to Epilepsy

Summary Diffusion imaging is a new imaging method based on Magnetic Resonance Imaging (MRI) that allows in vivo measurement of local diffusion properties of water molecules in the brain. Based on the Diffusion Tensor, it is increasingly used to characterize both grey and white matter. This can provide valuable information regarding cellular packing, cellular loss or regional edema in focal status epilepticus. Tractography is a method that reconstructs white matter neural tracts starting from any region studied. These imaging tools are increasingly used in clinical neurology and notably in epilepsy patients to detect subtle structural lesions that could be the cause of the epileptogenic activity. The precise and detailed knowledge of the trajectory of white matter tracts helps to plan difficult epilepsy surgical procedures and to better understand the propagation of epileptic seizures. Epileptologie 2007; 24: 60 – 65