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[The study of human papillomavirus(HPV) DNA expression in middle-ear carcinomas].

OBJECTIVE
To study the expressions of human papillomavirus DNA in the middle-ear carcinomas.


METHOD
A PCR method using consensus primers for the detection of HPV6,11,16,18 was applied in 5 biopsies of middle-ear carcinomas. Eight biopsies of mucosa in middle-ear and mastoid were concluded as controls.


RESULT
It was found that a resulting 80% (4/5) of the middle-ear carcinomas contained high-risk-type HPV DNA, while the 0%(0/8) of the controls.


CONCLUSION
The high prevalence of high-risk-type HPV in carcinomas of the middle ear suggests that viral infections may be an important etiologic component in the carcinogenic process.