{'fraction_non_alphanumeric': 0.061621621621621624, 'fraction_numerical': 0.03567567567567568, 'mean_word_length': 5.299319727891157, 'pattern_counts': {'":': 0, '<': 2, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Influence of 4,4'-(Isopropylidenedithio)bis(2,6-di-t-butylphenol) (DH-581) on Experimental Atherosclerosis in Rabbits 1

Summary The influence of orally administered 4,4'-(isopropylidenedithio)bis(2,6-di-t-butylphenol) (DH-581) on the development of cholesterol-induced atherosclerosis in rabbits has been investigated. When fed at a level of 0.3% to rabbits who are also being given a diet augmented with 2% cholesterol and 6% corn oil, DH-581 does not affect the course of the cholesterol-induced atherosclerosis. At this dietary level, however, DH-581 did cause reductions in liver triglycerides. When administered at a level of 1% of the atherogenic diet, DH-581 significantly lowers the severity of atheromata in the arch (p)<.05) and thoracic aorta (p<.01) of rabbits. These rabbits also showed consistently lower serum cholesterol and liver cholesterol and triglyceride levels. Serum triglyceride levels were variable.