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Cortical inhibition in alcohol dependence.

C. Event-related potentials (ERPs) obtained by using a cued continuous performance test (Go/No-Go task). Note the decrease in the responses of the alcohol-dependent subjects (indicated in green) compared with control subjects (indicated in gray). The dashed lines indicate the time of target presentation and the time of peak response (300 ms, P300). The alcohol-dependent subjects had diminished frontal activation during both conditions, indicating diminished inhibition (disinhibition).