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[Assessment of cardiac structure and function by echocardiographic values for male Balb/c mice].

AIM
To assess the parameters of cardiac structure and function of male Balb/c mice by the echocardiography.


METHODS
A total of 27 male Balb/c mice (from five to seven week old) were examined with a 13-MHz transthoracic linear-array transducer, hearts were removed from mice anesthetized with Nembutal, and the left ventricular (LV) mass were weighed.


RESULTS
Complete 2-dimensional echocardiography for cardiac structure and function were obtained. Hemodynamic parameters were recorded. A correlation existed between LV weight (x) and echocardiographic LV mass (y) with the 2D) guided M-mode method: y = 1.15x + 3.26, (r = 0.80).


CONCLUSION
Echocardiography appears to be a promising approach for noninvasively assessing LV mass and function in mice.