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DIABETES, PHYSICAL EFFORT, VISCERAL OBESITY AND SUBCLINICAL VASCULAR RISK FACTORS IN POSTMENOPAUSAL WOMEN

Objective: The impact assessment of type 2 diabetes, visceral obesity and physical effort on the development of subclinical vascular risk factors in postmenopausal women. Design and method: We divided 62 postmenopausal women in two groups: DM + 37 women with type 2 diabetes mellitus; and DM- 25 women without type 2 diabetes mellitus. The average age of them [yrs]: 64 and 67 (*p < 0,05). Following measurements were taken: BMI, total cholesterol (Tchol), triglycerides (TG), HDL and LDL cholesterol, blood pressure, ankle- brachial index (ABI), pulse wave velocity (PWV), visceral fat index. Each patient was evaluated cardiovascular risk according to SCORE and Framingham scales and intensification of physical effort according the short version of the Minnesota Leisure Time Activity Questionnaire (MLTPAQ). Statistical calculations were performed in the StatSoft Statistica 10. The t-student test was used for the statistical analysis. Results: We revealed following results in both groups: DM + and DM- respectively [*for p < = 0,05; **for p < 0,001; NS- negligible statistically]. Figure. No caption available. Women with diabetes were characterized by higher BMI, PWV, visceral fat index, number of patients on statin and cardiovascular risk according to Framingham scale. Normoglycemic women were characterized by higher level of Tchol, HDL and LDL cholesterol. Conclusions: ConclusionsVisceral obesity is more common in women with diabetes despite similar intensity of physical effort taken by both groups of patients.Diabetes adversely affects the aortic stiffness, which is expressed by a higher PWV score.Women with diabetes are characterized by a better lipid profile due to the more frequent treatment with statins in this group.