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Restoring Symmetry: Clinical Applications of Cross-Education

The “restoring symmetry” hypothesis poses that cross-education of strength — a crossed-limb adaptation after unilateral training — is best applied to clinical conditions presenting with asymmetries. Cross-education mechanisms should be viewed as evolutionarily conserved circuits that have a small impact on daily life but a meaningful impact for rehabilitation. Two recently published examples are hemiparesis after stroke and unilateral orthopedic injury.