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The spectrum of the cytopathological features of primary effusion lymphoma and human herpes virus 8‐related lymphoproliferative disorders

Human herpes virus 8‐related lymphoproliferative disorders are a complex and heterogeneous group of entities and some of them are eminently diagnosed by cytopathology. In a routine laboratory, these lesions account for less than 1% of the effusion fluids samples. However, they represent up to 30% of all the lymphoma diagnosis from effusion cytological samples and their consideration in the diagnostic flow chart is mandatory, especially in human immunodeficiency virus‐positive patients.