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Application of Silver Antibacterial and Antifungal Nanolayers for Ocular Prostheses Coating

The paper reports on antibacterial and antifungal properties of Ag‐doped Al2O3 nanolayers deposited by RF reactive magnetron sputtering on glass ocular prostheses. The study is provoked by the need of suppressing the infections caused by pathogenic microorganisms following the placement of ocular prostheses. This brings about the idea of forming protective coatings with antibacterial and antifungal properties on the prostheses. The surface elemental composition and the morphological characteristics of the coatings are investigated by XPS and SEM measurements. Further, the microbiological studies are conducted to establish the antibacterial and antifungal action of the nanocomposite Ag/Al2O3 layers against Gram‐positive and ‐negative bacteria, and Candida albicans. The strongest action of the layers is found against Pseudomonas aeruginosa − full inactivation after 2 h; Escherichia coli and Candida albicans – full inactivation after 5 h; Staphylococcus aureus − full inactivation after 24 h. The experimental findings suggest a very promising application of such antibacterial and antifungal Ag/Al2O3 nanolayers regarding the reduction of eye infections when implanting ocular prostheses.