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Phase synchronization of EEG in the head midline is associated with sleep-wakefulness stages

It is still unknown if the EEG phase-locking value (PLV) on the boundary between brain hemispheres is associated with sleep stages or not. Totally 39 EEG recordings were analyzed from the Expanded Sleep Database in EDF. Original EEG was decomposed into four bands. PLV was derived from Fpz-Cz and Pz-Oz. Using support-vector machine classifier for sleep-wakefulness classification, accuracies were 90.0% and 90.7% with linear kernel and radial basis function kernel, respectively. The phase-locking value derived from EEG bipolar leads between brain hemispheres are highly associated to sleep-wakefulness stages.