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The significance of computer-assisted semen analysis (CASA) for diagnosis in andrology and fertility prognosis.

The estimation of seminal parameters by CASA improves the objectivity, precision and reproducibility of values measured. Novel parameters, such as sperm velocity and characteristics of track direction, become measurable. An important advantage is direct on-line documentation. The biological significance of CASA parameters with respect to specific types of motility pattern or to fertility prognosis, however, is questionable. An important field is the analysis of pharmacological and toxicological influences on sperm motility. The evaluation of sperm morphology by CASA is not yet an established method.