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Direct analysis of individual aerosol particles by mass spectrometry

Individual aerosol particles are analyzed on the fly by on- line laser desorption ionization. The aerosol is sampled directly into a mass spectrometer where individual particles are detected by light scattering and then ablated by a high energy laser pulse. Ions produced by the ablation event are analyzed by time-of-flight mass spectrometry. Potential applications include laboratory investigations of aerosol reactions, field measurements of ambient particles, and detection of aerosol products and contaminants in manufacturing processes.