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Mapping of a human LIM protein (CLP) to human chromosome 11p15.1 by fluorescence in situ hybridization.

Using fluorescence in situ hybridization (FISH), we have localized the gene for cardiac LIM protein to human chromosome 11, between regions p14.3 and p15.2, most likely on 11p15.1. It is likely that CLP plays a regulatory role in muscle-specific gene expression in cardiac and skeletal muscles. The FISH data of human CLP provide a gene-associated marker for genetic mapping. 10 refs., 1 fig.