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Syphilitic alopecia and Jarisch-Herxheimer reaction.

The Jarisch-Herxheimer reaction was first described by Jarisch (1895) and elaborated by Herxheimer in 1902 (Stokes et al., 1944). The reaction was charaterised by a transient aggravation of the local and general manifestations, and most of the features would have gone by the next day. This report concerns a patient with syphilitic alopecia who showed a marked febrile reaction six hours after the first injection; alopecia also became diffuse and extensive but after treatment the hair grew again normally. To my knowledge this association has not been described before.