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Self-monitoring of Blood Glucose Requirements with the Use of Intermittently Scanned Continuous Glucose Monitoring: A Follow-up Analysis using Real-life data.

Hypoglycaemia-prone individuals with type 1 diabetes (T1D) who use intermittently scanned CGM (isCGM) systems spend about 5 hours/day in states where self-monitoring of blood glucose (SMBG) is indicated. Here we present estimates of the need for SMBG testing by retrospectively analyzing isCGM data from a cohort of real-world isCGM users. Data from 67 individuals were included in the analysis. Mean (SD) 3.18 (1.63) hours/day was spent in an SMBG-indicated state and the number of transitions to an SMBG-indicated state was 3.86 (1.46)/day. Frequency of clinically important hypoglycaemia (<3.0mmol/L (<54mmol/dL)) was median (IQR) 1.5 (0.6 - 3.4) episodes/week, of which only 50% were associated with a scan during the episode, and the average duration was 75.2 (63.9 - 91.8) minutes/episode. The need for continued SMBG testing remains important for all isCGM users and may affect overall cost-effectiveness of isCGM. Impaired awareness of hypoglycaemia and incidence of asymptomatic hypoglycaemia may be under-reported amongst real-life isCGM users in clinical practice.