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Immunohistological examination of a skin lesion in a Japanese case with hand, foot and mouth disease caused by coxsackievirus A6

Hand, foot and mouth disease (HFMD) is a self-limited and highly contagious viral infection that most commonly occurs in children. Serious outbreaks of HFMD occurred in Taiwan, Singapore and Finland in 2008 [1-3] and most recently in Japan in 2011 [4]. This epidemic was caused by coxsackievirus A6 (CVA6). CVA6-induced HFMD is known to present with atypical clinical manifestations [5-7]. This report describes the results of an immunohistochemical examination of a skin lesion in a Japanese adult with [...]