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Immunology of Dental Caries

Dental caries is the most widespread diseases in humans. In modern times, it has reached epidemic proportions. Dental caries is a microbiologic infectious disease of the teeth that ends in localized dissolution and destruction of the calcified structure of the teeth. Dental caries is a multifactorial disease that is caused by the host, agent, and environmental factors. The time factor is significant for the initiation and progression of dental caries. A wide group of microorganisms is established from carious lesions. S.mutans, Lactobacillus acidophilus, and Actinomyces viscosus are the main pathogenic species involved in the inception and development of dental caries.