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Use of a skin adhesive (octyl-2-cyanoacrylate) and the optimum reinforcing combination for suturing wounds

The adhesion strength of a skin adhesive, octyl-2-cyanoacrylate (Dermabond™), was measured under various conditions using porcine skin. The combined use of a skin adhesive and a skin closure tape (n=5) was significantly stronger than a single application of skin adhesive (n=5) (p<0.01). We have tentatively named the wound closure in which a skin adhesive and reinforcement material were combined the Reinforcing Combination Method. To obtain optimum conditions, further studies were done for sequence of application, type of reinforcement material, a number of layers, and width of the suture. The optimum condition for the reinforcement combination was established by applying one layer of skin adhesive over a skin closure tape, over one layer of skin adhesive, with a suture width of 4 cm. This reinforcement combination might be useful in clinical practice.