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Cough and ACE Inhibitors: The Truth Beyond Placebo

Angiotensin converting enzyme (ACE) inhibitors are extensively used for the prevention and treatment of cardiovascular diseases with a wide range of clinical recommendations. The use of ACE inhibitors can cause the onset of a dry cough, whose prevalence has probably been overestimated because of the lack of adequate control. A correct interpretation of available data requires a careful evaluation of placebo‐controlled studies to definitely assess the rate of the most frequent adverse event of ACE inhibition.