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Automatic Construction of Cell Genealogical Histories

Many research projects in the biological sciences have benefited from software and hardware that allows the automatic collection of large amounts of data. However, the full benefits of having this wealth of new data remain unrealized as much tedious analysis is still done by hand. Stem cell research is one sub-field suffering from this problem. Stem cell researchers have collected time-lapsed images of microwells populated with dividing stem cells. This data has allowed new analysis of stem cell division patterns. The data promises many new discoveries, but these discoveries are bottlenecked by the lack of automatic methods for generating cell genealogical histories.