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Uptake of dopamine by platelets in vivo

Circulating platelets of cats infused with 141C‐dopamine take up the amine against a concentration gradient, with maximal concen‐tration occurring 10 min after infusion. 58%, of the platelet‐bound radioactive dopamine was localized in a subcellular fraction rich in 5‐hydroxytryptamine (5‐HT) storage organ‐elles. The results support earlier work with human platelets showing in vitro dopamine