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[Predicting the day of ovulation with a do-it-yourself test].


 This study reviews biological and immunochemical methods for prediction of the day of ovulation. Biological methods include the calendar, the temperature, the ovulation pain and the cervix mucus methods. Because none of these is very reliable, immunochemical tests for the presence of luteinizing hormone (LH) in the urine have been placed on the market during the past few years. These tests are designed to show a color change in the test sample when urine LH is 40-50 IU/1. This value represents the peak of the preovulatory LH wave which lasts an average of 14 hours. According to information provided by manufactures of 5 tests available in the Netherlands, the chance of a positive test result with 1 test/day varies from 77% for LH-color, 80% for Discretest, 91% for Clearplan, 92% for Ovuquick, and 93% for Ovustick. In independent tests of Clearplan and Discretest, the brands most used in the Netherlands, laboratory technicians encountered persistent problems in interpreting the color indications of the test in terms of the LH concentration. Discretest sometimes gave false positives and Clearplan false negatives. The newer Ovuquick test, which works in 6-8 minutes compared to the 30 minutes required for LH-color, Discretest and Clearplan and 60 minutes for Ovustick, proved to be easier to read but gave false positives with LH concentrations as low as 20-30 IU/1. The authors conclude that do-it-yourself LH tests should be sold only by prescription.
