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Evaluation of the effect of Plasma on Post Burn Scars

Introduction: The skin is the largest organ of the body that serves multiple functions essential to the survival of the body, which may be compromised by the presence of burn, including thermal regulation, prevention of fluid loss by evaporation, hermetic barrier against infection and Sensory receptors that provide information about the environment. Aim of the work: The aim of this prospective study was to evaluate the effect of platelet rich plasma application on different types post burn scars. The hypothesis of the study is the previous options of the treatment of burn scars are satisfactory, if we can prove that platelet rich plasma, with using micro needling treatment therapy add an advantage in this field, it will be addition to the previous treatments. This study was conducted to answer the following questions: If PRP effective in treatment of post burn scars?, Can PRP applied to all types of post burn scars?, Is there are any complications?. Patients and Methods: This prospective clinical study was performed at the Plastic surgery department, Minia University Hospital in the period from February 2016 to July 2017, patients were counseled and signed informed consents, skin punch biopsies and photographs were obtained from all participants in this study. Results: 1. Demographic Data of the Patients: Twenty patients were enrolled in this study, the twenty patients completed the whole treatment and follow up protocol. Twenty patients, including eighteen females (90%) and two males (10%). Their ages ranged between 5 and 35 years (mean 16.7±10.8). All patients skin photo types were II-IV. Discussion: Burn scars represent a major challenge. In addition to significant morbidity to the scars themselves, side effects and lengthy courses of many therapeutic modalities represents an additional burden to the patients (Brusselaers et al., 2010). Recommendations: Further controlled studies with larger number of patients regarding the number of sessions and interval between sessions are recommended to estbestablish efficacy of platelet rich plasma therapy for the treatment of post burn scars.