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Conjugated iopanoic acid (Telepaque) in the small bowel: an aid in the diagnosis of gallbladder disease.

In 27 of 30 cases with nonvisualization of the gallbladder, opacification of the small bowel or colon by conjugated iopanoic acid was seen. Conjugated iopanoic acid is radiographically smooth and homogeneous and distinguishable from the granular particulate appearance of unabsorbed contrast medium. Conjugated material in the bile ducts, small bowel, or colon indicates iopanoic acid absorption from the gut, liver conjugation, and excretion through the biliary ducts. Visualization of the bile ducts, small bowel, or colon, in cases where the gallbladder has not been visualized, provides greater accuracy in the diagnosis of a pathological gallbladder.