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[Comparison of the efficiency of transluminal balloon angioplasty using EucaTAX and Cypher stents in patients with stable coronary heart disease].

OBJECTIVE
To compare the long-term results of transluminal balloon coronary angioplasty in patients after implantation of drug-eluting coronary artery stents with permanent or biosoluble polymer coatings.


MATERIAL AND METHODS
This was a prospective, comparative, single-center trial. It enrolled patients having at least 70% stenosis who had undergone intracoronary Cypher (SES) or EucaTAX (EUPES) stent implantation.


RESULTS
The trial included 602 subjects, including 282 patients with a placed EUPES stent and 320 patients with an implanted SES stent. Two years later, there was a higher rate of repeat revascularization in the EUPES group than in the SES group (16.3% versus 6.25%; p = 0.0001) and that of great unfavorable events in these groups (18.4% versus 7.8%; p = 0.001). According to the angiographic parameters of in-stent restenosis, the rate of repeat target-segment revascularization was significantly higher in the EUPES group than that in the EucaTAX group while stenting coronary arteries less than 3 mm in diameter, using stents more than 18 mm in length, as well as in residual stenosis of more than 12% as compared to the SES group.


CONCLUSION
In the SES group, the clinical outcomes were better than those in the EUPES group during 2-year follow-up; the rate of target lesion revascularization was significantly higher in the EUPES group.