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The constituents of fresh frozen plasma stored with citrate phosphate dextrose and their clinical implications.

The authors have investigated the constituents of fresh frozen plasma stored in citrate phosphate dextrose (CPD) at -20 degrees C. The results indicate abnormal characteristics of several of the constituents, whereas some others remain within normal values. This is attributed to preparation procedures with the addition of a CPD solution. Fresh frozen plasma being hyperosmolal, hypernatremic, hyperglycemic, hyperphosphatemic, normokalemic and containing normal values of protein, calcium, magnesium, and water carries a clinical implication for the physician as a guide for the treatment of the critically ill patient when large amounts of plasma are needed.