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From This Month's Histopathology

“While some authors have referred to this subtype of adenocarcinoma as ‘villous adenocarcinoma’ or ‘papillary adenocarcinoma,’ we chose the name ‘adenoma-like adenocarcinoma’ because that name can help to explain to clinicians why such lesions may be diagnosed as adenomas on biopsy. Furthermore, the term ‘villous carcinoma’ was used in earlier literature to refer to a typical CRC arising from a villous adenoma and hence may be misinterpreted. Regardless of the specific terminology used or minor variances in diagnostic criteria, it should be recognized that there exists an unusual adenoma-like subtype of CRC with particular clinicopathological features: it can mimic adenoma on biopsy, it spreads beyond the colon uncommonly and it rarely causes patient death. Its recognition may therefore influence treatment decisions (such as whether to offer adjuvant therapy).”