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GP162 The analgesic efficacy of ultrasound-guided qudratus lumborum block on postoperative pain and morphine consumption in children with appendicitis

Objectives To evaluate the analgesic effect of qudratus lumborum block (QLB) in pediatric patients administered before appendicitis. Methods This study was completed at the Faculty of Medicine, Vinnitsa national medical university, Vinnitsa, Ukraine, between September 2018 and Febrary 2019. In a prospective, double blind, randomized, placebo controlled clinical study, 38 pediatric patients scheduled for appendicitis operations were randomized to group Q (treatment group) or group C (controls). After receiving general anesthesia, group T received a QLB block using 0,3 mL per kg 0.25% bupivacaine on the right side, where as group C received a control block using 0,3 mL per kg 0.9% Sodium chloride. During the first 24 hours after surgery, the patient pain was evaluated using the visual analogue scale (VAS) at rest and while coughing. Postoperative patient controlled analgesia morphine consumption, VAS scores, and side effects were recorded. Results Of 24 patients, Group Q (n=14) had significantly lower VAS pain scores than Group C (n=10) both at rest and while coughing. The total morphine consumed was lower (5.2 ± 2.4) versus 17.3 ± 3.4 mg, p<0.001) in the 24 hours after surgery. Conclusion As part of a multimodal analgesic regime after appendicitis, morphine consumption and VAS pain scores were significantly lower among those receiving 0,3 mL per kg 0.25% bupivacaine administered for a QL block than among controls.