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Allergic contact dermatitis caused by glycyrrhetinic acid and castor oil

A 19-year-old woman with a past history of eczematous lesions at sites of contact with costume jewellery and adhesive dressings was referred for investigation of repeated episodes of contact dermatitis that occurred over a period of 3 years. The lesions involved the lips, the axillae, and the face. The patient implicated two lip balms, a deodorant, and a post-sun moisturizing cream. Patch testing was performed in two separate sessions. In August 2008, the patient was first tested with the North American Contact Dermatitis Group baseline series (AllergEAZETM; SmartPractice®, Calgary, Canada) applied on Finn Chambers® (SmartPractice®, Phoenix, AZ, USA), the antimicrobials/vehicles/cosmetics series, and the four suspected cosmetics, applied on IQ Ultra® chambers (Chemotechnique Diagnostics AB, Vellinge, Sweden) (Table 1). The patches were removed at D2, and the reactions were scored according to the criteria of the International Contact Dermatitis Research Group at D2 and D4. The patient’s positive reactions to colophonium and nickel sulfate were deemed to be of past relevance.