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Intravenous Bisphosphonate for Hypercalcemia Accompanying Subcutaneous Fat Necrosis: A Novel Treatment Approach

a history of difficulty during birth involving hypothermia, meconium aspiration, and/or asphyxia.' The skin lesions require only symptomatic treatment, but the condition is often accompanied by life-threatening hypercalcemia. Treatment regimens have involved fluid hydration, corticosteriods, furosemide, and a diet low in calcium and vitamin D. Recently, a patient report described oral administration of a bisphosphonate, etidronate, for an infant with the condition.' We report a novel treatment of this condition using intravenous administration of the bisphosphonate, pamidronate.