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[Characteristics and treatments of metastases to the central nervous system in patients with breast cancer].

Metastases to central nervous system (CNS) were found in 26 (18.2%) out of 146 patients with recurrent or advanced breast cancer. Surviving periods of the patients were ranged from 0.1 to 56.8 months, averaged 15 months. Three patients survive 56.8, 38.3 and 12.4 months respectively after the onsets of CNS metastases. Adrenalectomy in 2 cases, administration of Tamoxifen in one case and administration of 5'-DFUR in one case were effective to the patients respectively. Radiation therapy to 6 out of 8 cases and surgical removals of the tumors in 5 out of 7 cases were successful in the treatments.