{'fraction_non_alphanumeric': 0.02028397565922921, 'fraction_numerical': 0.0, 'mean_word_length': 5.586666666666667, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Prostate carcinoma cells that have resided in bone have an upregulated IGF‐I axis

Prostate cancer (PC) has a propensity to metastasize to the skeleton, inducing an osteoblastic response in the host. Recent epidemiological studies have suggested that circulating IGF‐I may be important for both the pathogenesis and dissemination of PC. We have postulated that tumor secreted IGF‐I in conjunction with endogenous IGF‐I contributes to the osteoblastic phenotype characteristic of metastatic PC.