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A novel furanocoumarin from Feroniella lucida exerts protective effect against lipid peroxidation

The protective effect of Feroniella lucida against lipid peroxidation was investigated. Bioassay‐guided separation using rat brain as a model led to the isolation of a new antioxidant furanocoumarin named feroniellamin (6) along with five known coumarins (1–5). The structure of 6 was characterized by interpretation of spectroscopic data. Feroniellamin inhibited lipid peroxidation with an IC50 value of 52 µm. Copyright © 2006 John Wiley & Sons, Ltd.