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Effect of Prehabilitation in Colorectal Cancer Surgery: A Systematic Review and Meta-analysis

Review question / Objective: Colorectal cancer increases with age, and elderly patients are associated with a poorer prognosis after colorectal surgery. Since comorbidity and frailty are associated with clinical outcomes, several strategies are introduced to improve clinical outcomes according to correct those.Despite efforts to improve the clinical outcome after surgery, patients with colorectal surgery still frequently experience complications. While Enhanced Recovery After Surgery has standardized principals, prehabilitation program varied among studies. The prehabilitation program according to the study showed differences in patient selection criteria, exercise, nutritional support, and methods of the outcome measurement. Therefore, various results have been reported regarding the effect of prehabilitation. The effectiveness of prehabilitation is still controversial. The aim of this study was to confirm the updated overall spectrum and measure the effect of prehabilitation in patients with colorectal cancer surgery.