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Estimates of genetic risks of exposure to ionising radiation and their use in radiation protection: The 1992 status

Presents a broad overview of the following themes: (i) naturally occurring genetic diseases in man; (ii) how genetic risk estimates are obtained and used in the sphere of radiation protection; (iii) the significance of the genetic results from the studies of A-bomb survivors in Japan; (iv) the association between paternal radiation exposures and risk of leukaemia in the children noted by Gardner and colleagues (1990) and (v) a reassessment of the conceptual framework of risk estimation and of estimated risks in the light of recent advances in the molecular biology of human genetic diseases.