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Kawasaki disease, myocardial infarction and coronary artery revascularization.

Kawasaki disease (KD) is the leading cause of acquired pediatric heart disease in North America and Japan. Cardiac sequelae, such as coronary artery aneurysms and myocardial infarction, are the major causes of the morbidity and mortality associated with KD. Three case scenarios are described illustrating the wide range of clinical presentations of myocardial ischemia in children after acute KD, varying from asymptomatic to fatal myocardial infarction. In addition, the present paper provides a review of the literature on myocardial infarction in association with KD and various modalities of coronary artery revascularization in children with myocardial ischemia secondary to KD.