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Blood Glucose Control In Type 1 Diabetic Rat, Considering Food Intake Effects

Diabetes is among of our times most widespread diseases. Currently, the main and effective treatment method to control blood glucose level in diabetics is insulin injection. In this research, animal experiments are done on rat as an appropriate experimental animal. The time-varying model of rat is used which considers the food intake effects, too. The controller is designed for the model (backstepping controller) to maintain blood glucose levels in a normal range and determine the insulin injection plan. Since the states of the model are not measurable totally, Kalman Filter is developed to estimate states successfully. Simulated results indicate the efficiency of the proposed backstepping controller in regulating the blood glucose level in type 1 diabetic rat.