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Suspicion of persistent or recurrent carcinoma of the larynx after radiation therapy.

At most interdisciplinary tumour centres, radiotherapy is of prime importance in the concept of therapy for the majority of the cases of laryngeal carcinoma treated, or it is even employed--exploratively and with curative intent--as the sole therapy at first. At all events initial radiotherapy occupies a dominant position today. Against this background the question is often discussed whether, after a 'low dose' has been attained (particularly in the case of a supraglottic tumour), a partial or total laryngectomy should be performed or the radiation dose substantially increased with the aim of obtaining a cure. However, the difficulties involved immediately after irradiation or later in recognizing a persistent or recurrent carcinoma and readily identifying it histologically may be very great. Various aspects of such situations--both diagnostic and therapeutic--are discussed in general and with reference to case histories.