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[A retrospective study of 3 cases of nephrotic syndrome with pulmonary thromboembolism].

OBJECTIVE
To study the nephrotic syndrome (NS) with pulmonary thromboembolism (PTE).


METHODS
3 cases of NS with PTE were reviewed.


RESULTS
The fibrinogen (mean 7.8 g/L), alpha-2-maccoglobulin (mean 21%) and cholesterol (mean 7.2 mmol/L) in the blood were higher in the NS patients with PTE. 1 of 2 patients was found to be membranous nephropathy. Ventilation/perfusion lung scan and a postmortem examination showed that bilateral, multiple pulmonary thromboembolism was found in 1 case. It was effective to use heparin and/or urokinase for NS with PTE.


CONCLUSIONS
NS exists in the hypercoagulable state in blood. It is easy to concomit PTE. Pulmonary artery angiogram should be done when NS with PTE was suspected. Besides glycocorticoids, the combination of anticoagulants and thrombolysis gave most favorable results for NS patients with PTE.