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The Clinical significance of Platelet Parameter Changes in Hypoxic-ischemic encephalopathy(HIE)

Objective To explore the Clinical effectiveness of the Platelet parameter in HIE. Methods 50 case of HIE who were final diagnosed, and the platelet total (PLT) Mean platelet volume(MPV) and platelet distribution width(PDW) in the acute period and recovery period were dynamic observed, It was compared with 50 Case of normal term Infant. Results PLT in acute period of HIE was obviously lower than that of the normal term infant(P0.01), MPV and PDW were obviously high than of the normal term Infants(P0.01). PLT, MPV and PDW in the recovery Period were no significantly different Compare with the normal term(P0.05). PLT in the case of HIE was farther low with exacerbation of HIE, whereas MPV, PDW was further high with exacerbation of HIE(P0.01). Conclusions It's a marker of evaluating the Severity and exacerbation of HIE by dynamic observing the platelet parameter.