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[Study of the phylogenetic relations of Puumala hantaviruses, by using the mutual information calculating method].

Phylogenetic relations were investigated in the group of Puumala viruses (the genus Hantavirus, the family Bunyaviridae) by the mutual information showing the similarity of the nucleotide sequences of S- and M-genome segments. There was evidence that recombination events might occurr in some Eurasian Puumala viruses (Scandinavian and West-Siberian genotypes). The investigation revealed the conservative sites available in the S and M segments that were common to most Puumala viruses, as well as the preservation of alternation and mutual arrangement of these sites in the S and M segments even for greatly diverging genotypes, which may be used in the detection of recombination events in Puumala viruses during further studies.