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Ontogeny of Lysozyme in the Rat 1

Summary Using the immunoperoxidase technique, LZM was detected in the kidney of 18-day rat fetuses. At the same time LZM was found to be present in circulating monocytes. After birth, a marked increase of the number of alveolar macrophages was observed, associated with intense LZM staining. The enzyme was detected in Paneth cells for the first time in 8 to 12 days after birth. These findings are discussed in relation to the known and postulated functions of LZM.