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New Data Mining Tools for Outcomes Analysis in Complex Clinical Problems

Duke University's Medical Center TMR™ perinatal data repository provided data for the current study. TMR™ has a robust data structure that has remained stable since 1986. It is the only known clinical database that has collected data on pregnant women for more than two decades, The first data extraction contained 71,753 electronic medical records for both low and high-risk pregnant women (and their infants) who had received prenatal care at DUMC, and its affiliated regional clinics, between 1/1/88 and 6/1/97. Each patient's electronic data was used for clinical patient care, and contained a potential 4000 to 5000 variables per record. This volume of data requires new approaches for data analysis and clinical decision support, since human information processing limitations become quickly overloaded by both an individual patient's data and the aggregate information collected for the perinatal patient population.