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Treatment of Inborn Errors of Metabolism

The results of a collaborative study of children treated on newborn mass‐screening program in Japan are described. Forty‐three cases of PKU, in which the dietary treatment was started between 9 to 35 days of life, were followed up, their ages ranging from 6 months to .6 years. DQ or IQ was found to be within normal range in all cases. As compared with IQ in untreated cases of PKU, an evident effect of early treatment was observed.