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The anaerobic threshold in cystic fibrosis: Comparison of V‐slope method, lactate turn points, and Conconi test

Physical exercise can improve sputum clearance in patients with cystic fibrosis (CF). To set up individual training protocols it is desirable to know the anaerobic threshold (AT). Established methods such as blood lactate measurements and ergometry can only be performed in specialized centers. Conconi showed that the heart rate threshold (HRT), i.e., the deflection point from the linear relationship between work load and heart rate, correlated significantly with the AT in healthy adults. To assess the reliability of the HRT in CF, we performed ergometry in 32 CF patients (mean age, 21.0 ± 5.5 years; mean Shwachman score, 77.8 ± 12.0) according to the Conconi protocol. The HRT was compared with the aerobic threshold (AeT) as determined by the V‐slope method and with two turn points in the lactate performance curve (LTP1, LTP2).