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Radiotherapy for Orbital Pseudotumor: The University of Florida Experience

Abstract Background: To evaluate outcomes after definitive radiotherapy for orbital pseudotumor. Methods: We reviewed adult patients treated between 1971 and 2012. Results: 20 patients with 8.0-year median follow-up were analyzed. Symptoms improved in 75% of patients: 40% showed a complete response, 35% partial response, and 20% had stable disease. The disease progressed in 1 and recurred in 8 patients. Local control rates were 63% and 53% at 5 and 10 years, respectively. The most common toxicities were cataracts (10%) and dry eye (10%). Conclusions: Radiotherapy for orbital pseudotumor is well-tolerated and results in long-term control in most patients, with local control in over half.