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Endothelial cell micro-motion monitored by ECIS during monocytes application

We measured the endothelial cell micro-motion by the Electric Cell-substrate Impedance Sensing (ECIS) system during monocyte application. Application of monocytes to the confluent bovine aortic endothelial cell (BAEC) cultured on the electrode caused a slight decrease in the measured electrical resistance compared with the static control BAEC. This means that gaps between cells and/or between cells and substrates became wider. These results imply that the focal adhesion complex and cytoskeletal structure of BAEC change dynamically during monocyte application.