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Translational and Morphological Effects of Signalling Alcohols on C. albicans

Candida albicans is a polymorphic yeast that can cause life threatening systemic infections in immunocompromised individuals. One key attribute of C. albicans that enhances pathogenicity is the capacity to switch morphology from vegetative to filamentous modes in response to specific environmental conditions. Stressful changes in such cellular conditions commonly cause a rapid inhibition of global protein synthesis leading to altered programmes of gene expression.