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Fresh frozen plasma transfusion for reversal of prolonged post‐anaesthesia apnoea

summary An 18‐year old woman admitted for tonsillectomy developed prolonged post‐operative paralysis after anaesthesia with mivacurium. Investigation revealed a decreased cholinesterase activity because of a homozygous atypical and heterozygous K variant of the cholinesterase gene. Transfusion of fresh frozen plasma was associated with reversal of the respiratory paralysis and complete recovery.