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Familial spontaneous pneumothorax

We would like to report a series of four newborns in an extended family who have had spontaneous pneumothorax soon after birth without any obvious cause (fig 1). There is no history of pneumothorax in anyone else in the family.



 Figure 1 
Genetic map showing the positions of the neonates with spontaneous pneumothorax in the extended family.



A female infant was born in good condition at term by emergency caesarian section after a normal pregnancy. She had a spontaneous right sided tension pneumothorax within a few minutes of birth. The pneumothorax was drained. There was no evidence of surfactant deficiency on any of the initial chest radiographs. After discharge she went on to have three other …