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Rapid fat‐suppressed isotropic steady‐state free precession imaging using true 3D multiple‐half‐echo projection reconstruction

Three‐dimensional projection reconstruction (3D PR)‐based techniques are advantageous for steady‐state free precession (SSFP) imaging for several reasons, including the capability to achieve short repetition times (TRs). In this paper, a multi‐half‐echo technique is presented that dramatically improves the data‐sampling efficiency of 3D PR sequences while it retains this short‐TR capability. The k‐space trajectory deviations are measured quickly and corrected on a per‐sample point basis. A two‐pass RF cycling technique is then applied to the dual‐half‐echo implementation to generate fat/water‐separated images. The resultant improvement in the signal‐to‐noise ratio (SNR) and contrast‐to‐noise ratio (CNR) was demonstrated in volunteer studies. Volumetric images with excellent spatial resolution, coverage, and contrast were obtained with high speed. The non‐contrast‐enhanced SSFP studies show that this technique has promising potential for MR angiography (MRA). Magn Reson Med 53:692–699, 2005. © 2005 Wiley‐Liss, Inc.