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Course of glycaemia in poorly controlled type 2 diabetes patients 2.5 years after optimizing oral treatment in general practice

In general practice, glycaemic control in poorly controlled type 2 diabetes patients (DM2) can be improved without insulin therapy by optimizing oral treatment (1,2). It is not well known, however, how long normoglycaemia can be maintained without exogenous insulin (3). It is also uncertain whether tight glycaemic control can be maintained in the long run with insulin therapy (4 6). The aim of this prospective study was to investigate whether poorly controlled DM2 patients in general practice, both those who were optimized with only oral hypoglycaemic agents (OHA) treatment and those who were switched immediately to insulin therapy, had acceptable glycaemic control 2.5 y after optimization.