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Beta and beta-related sialoglycoproteins in the human red cell membrane.

Recent studies on beta and beta-related sialoglycoproteins (SGPs) in the human red cell membrane are reviewed. These SGPs are transmembrane glycoproteins with conserved cytoplasmic domains that interact with the membrane skeleton via protein 4.1. The inheritance of these SGPs is described, and the possible locations of Gerbich (Ge2 and Ge3) and Wb blood group antigens reviewed.