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EPIDEMIOLOGY AND PATHOPHYSIOLOGY OF CORPUS CARCINOMA

In Sweden each year between 14,000 and 15,000 new cases of cancer are reported among Sweden’s total female population, comprizing about 4 million women. This gives an incidence of approximately 3,500 p.p.m.* Cancer of the breast is the most frequently reported tumor in females while cancer of the endometrium rates as number five in order of frequency, being found in approximately 5.3 per cent of all Swedish female cancer cases. Table I indicates the sites and frequency of cancer in Swedish females during 1971. This table is based on a total of 14,59 1 new cases reported in a female population of about 4 million. The incidence of endometrial cancer in Sweden during the years 1962-1971 has been slowly increasing. At present between 700 and 800 new cases are reported annually, giving an incidence of approximately 190 p.p.m. Fig. 1 shows the incidence of endometrial cancer in Sweden for the years 1962-1971. The age specific incidence of endometrial carcinoma is shown in Fig. 2. This disease is very rare before the age of 40. Only 1.5 per cent of the corpus cases in Sweden occur before the age of 40. The peak incidence occurs in the 70th year of life when it reaches approximately 500 p.p.m. There is an increase in number of cases diagnosed in the age group 50-55 years, probably reflecting increased diagnostic activity in this age group. (Cancer Registry) (3). The outcome of treatment of carcinoma of the endometrium is very favourable (Table 11). In stage I, when the disease is confined to the endometrial cavity and the patient is operable, the