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The role of lymphadenectomy in esophageal cancer

Lymph node metastases are common in esophageal cancer and are associated with a poor prognosis. Resection and examination of 15–18 lymph nodes is required for adequate staging of esophageal cancer. Improved survival is associated with involvement of five or fewer nodes or lymph node ratio (LNR) of < 0.10–0.20. More extensive lymph node dissection during esophagectomy offers improved staging but may also provide therapeutic benefit in terms of control of locoregional disease and possibly improved overall survival. J. Surg. Oncol. 2009;99:189–193. © 2008 Wiley‐Liss, Inc.