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ASSESSMENT OF OXIDATIVE METABOLIC SYSTEM PARAMETERS AFTER CORRECTION WITH THE FLAVONOID DIHYDROQUERCETIN

A total of 71 residents, living for more than 10 years in the Khanty-Mansiysk Autonomous Region with poor-quality water treatment and not employed in the manufacturing sector, were examined: 29 (40,8%) men and 42 (59,2%) women, average age 38,3 ± 8,9 years. The indicators of POL above the reference values, and AOZ – below the physiologically optimal values were established. After receiving for metabolic correction antioxidant drug dihydroquercetin for a month there was a statistically significant decrease in primary (GPl, p=0.025) and secondary (TBA-AP, p=0,049) of LPO products, significant 1,8-fold increase of total antioxidant activity (p<0,001), statistically significant increase of thiol status almost 1,2 times (p=0,036), decrease of COP more than 3 times (p<0,001).