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Nomenclature for Factors of the HLA System, 1989

The WHO nomenclature committee for factors of the HLA system met during the 7th International Congress of Immunology in Berlin in August 1989 to consider additions to the previous report on Nomenclature for factors of the HLA system 1987 [l, 21. This report, taking into account only new data on DNA sequences of alleles and of three new loci, therefore concerns only the naming of new alleles and loci defined by nucleotide or inferred amino acid sequences. It should therefore be considered as a supplement to and used in conjunction with the 1987 report cited above. Thus table1 Names for genes in the HLA region includes the new genes named for the first time in this report and updates table 1 of the 1987 report. Table 2 Designations of HLA-A, B and C alleles updates table 3 of the 1987 report, and tables 3-5 Designations of the HLA-DR, DQ and DP alleles update table 4 of the 1987 report. Tables5-9 and comments of the 1987 report relating to serological and cellular determinants remain unchanged, and will be considered in a later meeting of the Nomenclature Committee. The naming of the new genes and alleles listed in tables 1-5 of this report follows the principles stated in the 1987 report.