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Fungi in fluids--a hazard of intravenous therapy.

Summary Fluid contaminated with fungi was inadvertently administered intravenously to two patients. In both instances the bottle was cracked. However, apparently intact bottles can also show visible signs of growth. Both patients were treated with amphotericin B in a dose of 0·25 mg per kg body weight for 24 hr without toxic effects. There was complete recovery. It is suggested that all bottles used for intravenous therapy should be carefully inspected before use.