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Cell Mediated Neural Defense Against Pathogen within Olfactory Neuroepithelium of Fish

Pseudapocryptes lanceolatus (Bloch 1801) and Lepidocephalichthys guntea (Hamilton, 1822) are two different teleostean species showing distinct ecomorphological variation in the olfactory apparatus in respect to their concern environmental habitat These species are generally residing in turbid or hypoxic condition and have a high risk to sniff variable pathogens along with water during olfaction through the nostrils. The present study pertinently deals with the question that ‘How peripheral olfactory neural system protects itself against invading pathogens and restore olfactory neuroepithelial integrity in fish?’ The olfactory apparatus of adult P. lanceolatus and L. guntea were dissected out and immediately fixed in 2.5% glutaraldehyde in 0.1 (M) phosphate buffer (pH. 7.2) at 4°C for 2 hours (primary fixation) and 1% osmium tetraoxide in the same buffer for 1 hour (secondary fixation). The ultrathin sections (70-90) nm were stained with uranyl acetate and lead citrate, examined under transmission electron microscope