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Experimental radiofrequency telethermohypophysectomy.

✓ A new means of producing well-delineated lesions of the pituitary gland by the heating of implanted electroseeds with electromagnetic radiation has been tested in a series of eight adult baboons (Papio anubis). The technique shows promise as a future simple and safe means of depressing anterior or posterior pituitary function in a controlled fashion over a period of time. In addition, possible fallacies relating to the rationale justifying total sellar hypophysectomy are considered. The authors believe that progressive depression of pituitary function may represent a more logical therapeutic approach to patients requiring hypophysectomy for the palliation of malignant disease, diabetic retinopathy, or eosinophilic pituitary adenomas.