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Caffeine and Citrate Aurantium Supplementation Alter Resting Cardiac Autonomic Function but Not During Recovery: 2411 Board #247 June 1 11

PURPOSE: To examine the combined effects of the pre exercise complex Citrate Aurantium and Caffeine (CA+C) on cardiac autonomic activity following ingestion and immediately after high-intensity anaerobic exercise in habitual caffeine users. METHODS: Ten physically active males (25.1± 3.9 years; mass 78.7± 9.5kg) who habitually consume caffeine (≥ 1 serving a day [95mg] 4 days a week) participated. This was a double-blind crossover design, where either a CA+C or a placebo capsule was consumed followed by a 45-min ingestion period, a repeated Wingate protocol, and a 45-min recovery period. Cardiac autonomic activity was assessed through Heart Rate (HR), plasma epinephrine (E) and norepinephrine (NE), and markers of Heart Rate Variability (HRV): root mean squared of successive R-R differences (RMSSD); Standard Deviation of R-R intervals (SDNN); High-Frequency (HF); Low-Frequency (LF); and its ratio (LF:HF). Markers were taken at four time points: pre-Ingestion (PRE-ig), 40-45-min post (Postig); Wingate recovery (PRE-rcv), 40-45-min post recovery (Post-rcv). RESULTS: Markers that violated normality were naturally log transformed prior to further analysis (ln). Pre-planned comparisons were performed to assess differences between pre and post time points as well as the corresponding time point of the other trial within their respected phase. During the CA+C trial, an increase in HR, lnSDNN, lnLF, EPI, and NE were observed at Post-ig when compared to Pre-ig (p≤0.05). Significant differences were observed in all markers, except LF:HF, during the CA+C and PLA trials from the Pre-rcv to Post-rcv (p≤0.05). CONCLUSION: The consumption of CA+C stimulates sympathetic activity during rest (e.g. ingestion phase) without influencing parasympathetic activity. CA+C provides no influence over cardiac autonomic recovery.