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Interleukin‐2 receptor positive T and B cells in children with acute severe asthmatic attack

Subpopulations of interleukin‐2 receptor (IL‐2R)‐positive CD4 and CD8 T cells and IL‐2R+ CD20 B cells in the peripheral blood lymphocytes as well as serum concentrations of soluble IL‐2R (sIL2R) were measured in children aged 1–7 years who suffered acute severe asthmatic attack. Subpopulations of CD4+ IL‐2R+ cells, CD8+ IL‐2R+ cells and CD20+ IL‐2R+ cells in the peripheral blood lymphocytes at acute severe asthmatic attack phase were significantly higher than those at non‐asthmatic attack phase (P < 0.02, P < 0.03 and P < 0.02, respectively).