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Effect of Memorial Sloan-Kettering Cancer Center (MSKCC) nomogram to avoid conventional axillary dissection of one node-metastasis Japanese patients with breast cancer.

e11531 Background: Our aim was to define the role of MSKCC nomogram in avoiding conventional axillary dissection of one node-metastasis breast cancer patients.


METHODS
Between January 2009 to November 2010, clinically axillary node negative consecutive 186 patients underwent sentinel lymph node biopsy using 12 mg Indigo carmine in our institution.


RESULTS
In 14 (7.5%) of the 186 cases with metastatic axillary nodes were node positive and underwent axillary dissection. Final pathological results shows 10 of 14 patients revealed one node-metastasis and four patients revealed more than 2 node-metastasis. Assessment of MSKCC nomogram, average of probability of spread to additional lymph node were 25.4% for the former group, 54% for the latter group.


CONCLUSIONS
Our study confirms MSKCC nomogram's role in sentinel lymph node biopsy of breast cancer surgery. MSKCC nomogram may prove useful in avoiding benefit from axillary dissection of only one node-metastasis breast cancer patients.