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[The features of the pathologic changes in chronic oxalate stone disease after 16 week of experimental phase].

AIM
to study the pathologic features of chronic oxalate stone disease.


MATERIALS AND METHODS
a model of the experimental oxalate stone disease was done in rats that drank the 1% ethylene glycol solution for 16 weeks. The pathologic analysis of the rats kidneys was done.


RESULTS
After 16 weeks of oxalate stone disease modeling in all parts of kidneys the large crystals deposits were found, which plugged renal tubules. Moreover, purulent calculous pyelonephritis developed complicated by fibrosis.