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The cDNA and derived amino acid sequences for rat and human synaptophysin.

The letters on the left of the sequence designate the species origin (R=rat, H=human). The deduced amino acid sequence is shown in single letter code. Putative transmembrane spanning regions are delineated by a dotted line and labeled Ml to M4. Peptide sequences determined from purified rat synaptophysin are underlined and designated PI to P4. The 15 positions where there are differences between the human synaptophysin amino acid sequences are marked with asterisks. The vertical arrows denote the position of two mapped introns in the rat synaptophysin gene. The conserved AT-sequence in the 3' untranslated regions is boxed.