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[System of antioxidant defense and activity of lysosomal hydrolase in the stomach mucosa in ulcer disease].

A state of blood antioxidant system and patterns of destructive processes in gastric mucosal membrane were studied under conditions of various gastroenterological diseases. Compensatory activation of glutathione peroxidase in erythrocytes and increased consumption of alpha-tocopherol and retinol were observed in these pathological forms. These alterations became less distinct during chronic development of gastric ulcerous disease simultaneously with elevation of destructive processes in gastric mucosal membrane as lysosomal endopeptidases were stimulated.