{'fraction_non_alphanumeric': 0.027186761229314422, 'fraction_numerical': 0.01773049645390071, 'mean_word_length': 5.182481751824818, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
In-vivo monitoring of tissue oxygen saturation in deep brain structures using a single fiber optical system.

We propose a single fiber optical system for monitoring tissue oxygen saturation (sO2) based on continuous-wave reflectance spectroscopy in the visible wavelengths. The system is designed for measurements in deep brain structures by stereotaxically implanting the 200 μm-core fiber probe into the tissue of interest. Monte Carlo (MC) simulations were used to estimate the measurement tissue volume between 0.02-0.03 mm3. Experiments in an optical phantom indicated the system had a root mean squared error (RMSE) of 4.21% compared with a commercial fluorescence-based tissue oxygen partial pressure measuring system. Finally, we used the system for continuously monitoring tissue sO2 from a highly-localized volume in anesthetized mice.