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The Effects of Whey vs. Soy Protein at Breakfast on Satiety Response, Energy Intake and Metabolism: 2336 Board #349 June 1 3

PURPOSE: To determine the effects of animal-based (whey) compared to plant-based (soy) protein on perceived satiety, hunger, fullness, desire to eat, prospective food consumption, thirst, energy metabolism and subsequent energy intake. METHODS: Seventeen healthy men and women (age: 27 ± 7, BF%: 21.5 ± 6.9) consumed three isocaloric breakfast smoothies with 40% of energy from either whey, soy, or control (no protein) in a double blind, randomized crossover design. Participants completed a visual analog scale (VAS) of appetite profile and thirst (before, 0, 60, 120, 180 minutes). Indirect calorimetry was used to determine the effect of a meal (TEM) (at 45-60, 105-120, 165-180 minutes). In addition, energy intake at lunch was recorded. RESULTS: There was a significant difference in hunger (p = 0.03), satiety (p = 0.001), fullness (p = 0.001), desire to eat (p= 0.03), and prospective food consumption (p = 0.04) between the three breakfast conditions. Measures of satiety and fullness were higher whereas hunger, desire to eat, and prospective food consumption were lower after consumption of whey protein compared to control. A significantly higher (p < 0.05) respiratory quotient (RQ) and lower oxygen consumption (VO2) was observed for whey and soy compared to control condition. In addition, a significantly higher (p < 0.05) energy intake at lunch was observed after control (770 ± 289 kcals) compared to whey condition (654 ± 252 kcals). However, there was no significant difference (p > 0.05) in energy intake between soy (696 ± 296 kcals) and whey or control conditions. CONCLUSIONS: Consuming whey or soy protein at breakfast led to similar perceptions of appetite profile as well as lower energy intake at lunch, which may aid in weight management efforts among individuals following a vegan or vegetarian diet.