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Supported Nanoparticles with Advanced Release-Recognition Properties for Bioapplications

Introduction Innovative research in the biomedical field is the realization of polymeric systems containing recognition cavities. Molecular imprinting technology allows the realization of polymeric materials demonstrating selectivity towards specific molecules (template) through monomer(s) polymerization “around” the template: different polymerization methods are available and in this study precipitation polymerization was used (1), allowing a polymeric material in the shape of nanospheres to be obtained. To improve recognition properties of particles in water the innovative method was the use of membranes to support the imprinted nanospheres. With this method, enhanced membrane properties can be expected, taking advantage of specific nanoparticle characteristics (2). Current research is focused on searching for innovative biomedical uses of these materials as extracorporeal purification systems or recognition-able implantable devices.