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Metastatic Ovarian-Cell Carcinoma of the Subcutaneous Tunnel during Intraperitoneal Chemotherapy

Sir: Intraperitoneal (i.p.) administration is a new approach to the treatment of tumors with extensive peritoneal involvement (I, 2). The spread of ovarian carcinoma is mainly local and even in advanced stages generally is confined to the intraperitoneal cavity (2). In such instances intraperitoneal chemotherapy may yield satisfactory results (3). The complications of the procedure are similar to those observed during peritoneal dialysis, because the treatment requires insertion of a peritoneal catheter and the use of standard dialysis solutions. This letter describes an unusual complication of intraperitoneal chemotherapy i.e. the spread of IIIetastatic ovarian carcinoma in the subcutaneous tunnel of the catheter .