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Granulocyte elastase α1‐proteinase inhibitor complex measurement in very low birthweight infants with severe intraventricular hemorrhage

We investigated the relationship between the levels of granulocyte elastase α1‐proteinase inhibitor complex (E‐α1‐PI) in plasma and severe intraventricular hemorrhage (IVH) in very low birthweight infants. The concentrations of E‐α1‐PI and the ratio of the concentrations of E‐α1‐PI to polymorphonuclear leucocyte counts within 24 h of birth in infants with severe IVH were significantly higher compared with those in infants without severe IVH. E‐α1‐PI seems to be a useful indicator of IVH.