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Correlation between Serum Triglyceride Levels and Severity of Stroke.

Although dyslipedimia is a well established risk factor for coronary artery disease, its relationship to ischemic cerebrovascular disease has remained unclear, perhaps because of the heterogeneous nature of stroke. The relationship between plasma lipid abnormalities and ischemic stroke remains controversial. The aim of this study is to investigate if serum Triglyceride(TG) levels predict stroke severity on admission.


MATERIAL
Sixty patients of acute ischemic stroke who were admitted within 24 hours of development of symptoms were included in this study. Fasting serum Triglyceride(TG) levels estimated in mg/dl and converted to mmol/L by multiplying by 0.01129. Stroke severity on admission was assessed using Scandinavian Stroke Scale (SSS). The patients were divided into 2 groups: those with severe stroke (SSS ≤25) and those with mild/moderate stroke (SSS >25).


OBSERVATION
In this study the number of patients with severe stroke were 22 of which 21 had Triglyceride(TG)≤2.3mmol/l and only 1 patient had Triglyceride(TG)>2.3mmol/l while those with mild to moderate stroke were 38 of which 28 had Triglyceride(TG)≤2.3mmol/l and 10 patients had Triglyceride (TG)>2.3mmol/l. The mean of Triglyceride(TG) levels in patients with severe stroke is 1.002+/-0.385 mmol/l and that in patients with mild to moderate stroke is 1.790+/- 0.887 mmol/l.


CONCLUSION
In this study, mean serum triglyceride levels were significantly lower in patients with severe stroke when compared to patients with mild to moderate stroke. As per this study smoking, obesity, hypertension, IHD, diabetes mellitus, age and sex of an individual do not influence levels of serum triglyceride levels.