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CROSS‐REACTIONS AND DETERMINANT STRUCTURE OF HUMAN FIBRIN‐STABILIZING FACTOR (FACTOR XIII)

In continuation of earlier investigations the determinant structure of human fibrin‐stabilizing factor (factor XIII) was analysed by comparative determinant analysis (CDA). Two determinants, P1 and A were distinguished; P1 is shared with all subhuman primates studied, while it is missing on all non‐primate homologues. A is found on both primate and non‐primate homologues. The possible presence of an additional network determinant is discussed. There is no human species‐specific determinant.