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Cadherin‐related family member 3 gene impacts childhood asthma in Chinese children

A missense variant (rs6967330) of the gene encoding cadherin‐related family member 3 (CDHR3) was associated with recurrent severe exacerbations in pre‐schoolers. However, there were limited data on its relationship with pre‐school lung function and school‐age asthma. This study replicated the association between polymorphic markers at the region of CDHR3 around rs6967330 and wheezing phenotypes in two independent cohorts of Chinese children.