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Studies on antiinflammatory activity of taraxasterol acetate from Echinops echinatus in rats and mice

Taraxasterol acetate, a triterpenoid found in several plant species, demonstrated antiinflammatory activity in albino rats against carrageenan, formaldehyde and adjuvant induced inflammations in doses between 10 and 100 mg/kg. Quantitative comparison of the activities of the alcoholic extract of Echinops echinatus, and taraxasterol acetate extracted from the former, suggested the presence of one or more minor, but probably more potent, antiinflammatory constitutent(s) in the original plant extract.