{'fraction_non_alphanumeric': 0.018, 'fraction_numerical': 0.01, 'mean_word_length': 5.076923076923077, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
An Investigation of the Effect of Curcumin (Turmeric) Capsule on the Severity and Duration of Dysmenorrhea in Students of Iran University of Medical Sciences

BACKGROUND Dysmenorrhea is a very common and serious problem in women causing physical issues, mental issues and absence from social activities. Also, it is necessary to consider safety and side effects of new treatments. This study was designed to investigate the effect of curcumin (turmeric) capsule on severity and duration of dysmenorrhea. This study is a double blind randomized controlled clinical trial, conducted after obtaining informed consent form girls who were willing to participate in the study who complained of dysmenorrhea for the past 2 months. They were screened for two months and demographic questionnaire, menstrual characteristics, severity of dysmenorrhea were recorded. At the end of the two cycles, severity of their dysmenorrhea was marked by Verbal Multi-Dimensional Scoring, and those who had grade 2 dysmenorrhea based on the questionnaire enrolled to the study and were randomly assigned into two randomized blocks - curcumin group and placebo group. By considering 0.05 % type I error, Type II error β = 0.2 and the observed mean difference of 1.2 from a previous study, 37 subjects were included in each group. Intervention group curcumin containing 500 mg turmeric extract made by Karen Pharmaceutical Company with 2 capsules with food for the first three days of menstruation were used for two cycles and