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Visualisation of the circumventricular organs by fluorescence endoscopy

The circumventricular organs are highly specialised sites in the brain. They lie outside of the blood–brain barrier, are located periventricularly, and are thought to play an important role as the gateway through which information reciprocates between the outside and inside of the brain.1 We have attempted to visualise the circumventricular organs with the use of a fluorescence endoscope at the time of ventriculoperitoneal shunt revision.

A 71 year old man presented with progressive decline in mental acuity and gait disturbance. A ventriculoperitoneal shunt had been placed for normal pressure hydrocephalus following cerebral contusion 20 years before. The shunt was found …