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[Contribution of cones to activation of the slow PIII-potential of the frog retina].

A cone-specific subcomponent was separated from the slow PIII response of the frog retina. The time-course of cone sPIII was similar to [K+]0 decrease induced by the cone excitation. In comparison with rod sPIII, the cone sPIII had faster time-course, considerably smaller size and often fell below zero line. The data confirm principle similarity of rods and cones mechanism of excitation but suggest that their off-reactions are different.