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A case of glycogen storage disease type Ib presenting with prolonged neonatal hypoglycaemia and minimal metabolic abnormalities

powder residues (3,4). In conclusion, this case illustrates how drug testing not only in conventional matrices, which account for acute exposure, but also in nonconventional matrices can shed light on past and possibly chronic exposure and can disclose the situation of an infant living in an unsafe and high-risk environment in which exposure to drugs of abuse takes place. The hair is always available and gives information on the past exposure as it grows by approximately 1 cm per month and accumulates drugs (5). It is particularly useful if the results of urine analysis are negative during acute investigation. The accurate assessment of both acute and chronic exposure of a young child to drugs of abuse through the objective use of a biomarker is of major importance because it provides the basis for appropriate immediate treatment, adequate medical follow-up and social intervention. In case of any acute exposure to drugs of abuse or of postnatal withdrawal syndrome, we suggest to investigate further the possibility of chronic exposure.