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Propofol‐nitrous oxide versus sevoflurane‐nitrous oxide for strabismus surgery in children

Vomiting is a common problem following strabismus surgery. We compared the effects of propofol‐N2O and sevoflurane‐N2O on the incidence of oculocardiac reflex and postoperative nausea and vomiting. Forty unpremedicated children, aged 3–15 years were randomly assigned to two groups of 20 patients. In group 1, anaesthesia was induced and maintained with propofol infusion(173 ± 41 μg·kg−1·min−1). In group 2, anaesthesia was induced with N2O (66%) in O2 and incremental sevoflurane via face mask and maintained with sevoflurane. Both groups received 66% N2O in O2 throughout surgery. The overall incidence of vomiting and antiemetic requirement in the first 24 h was significantly higher in sevoflurane‐N2O group than propofol‐N2O group (P< 0.05). The propofol‐N2O group had significantly more episodes of oculocardiac reflex than sevoflurane‐N2O group (P< 0.05). Propofol‐N2O anaesthesia results in a significantly lower incidence of postoperative vomiting, yet a significantly higher incidence of oculocardiac reflex.