{'fraction_non_alphanumeric': 0.029354207436399216, 'fraction_numerical': 0.008806262230919765, 'mean_word_length': 5.6, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Safe, selective, and scalable carbenes

Description The synthesis of reactive carbene intermediates is made simpler and safer Across chemistry, new strategies to access transient and reactive intermediates are of interest for further research and synthetic applications. In organic chemistry, carbenes are one such intermediate. These include any neutral carbon molecule with two unshared valence electrons (1, 2). Carbenes can participate in a variety of reactions such as dimerization, formation of three-membered rings, and bond insertions. However, accessing these valuable intermediates has traditionally required the use of precursor molecules that are unstable or are limited to specific types of reactions (3, 4). For example, nonstabilized alkyl-substituted carbenes are highly reactive intermediates, which limits their use in synthetic transformations (3). On page 649 of this issue, Zhang et al. (5) report a means to access both stabilized and nonstabilized carbenes under safe and simple reaction conditions.