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Research progress of the influence of sperm plasma membrane protein glycosylation on sperm maturation

Protein glycosylation is the covalent connection between monosaccharide or glycan and specific moieties of target proteins. As a ubiquitous and complex post-translational modification of proteins, glycosylation plays an important role in protein function, stability and subcellular localization. During the process of spermatogenesis in testis and maturation in epididymis, abundant glycosylation of sperm membrane proteins occurs, which plays an important role in the gradual maturation of sperm structure and function. In this paper, the research progress of glycosylation of sperm membrane protein on sperm maturation is reviewed.