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Further Evidence for the Lymphocytic Nature of Leukaemic Reticuloendotheliosis (Hairy‐Cell Leukaemia)

Summary. A case of hairy‐cell leukaemia was studied by conventional cyto‐chemical, electronmicroscopic and immunofluorescence techniques. This condition is often known as leukaemic reticuloendotheliosis (LRE) but the nature of the proliferating cells has been in doubt. The accumulation of immunoglobulin‐synthesizing cells in the peripheral blood suggests that the involved cells are lymphocytes and no evidence for a reticular or endothelial origin of the LRE cell could be found.