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Quantitative triple fluorochrome labeling study of lathyritic-rat mandible.

The present study was conducted to quantify the amount and distribution of new bone formation by triple fluorochrome labeling sequence in different areas of the mandibular bone of the control and lathyritic animals. The data was subjected to statistical analysis. Osteolathyrism significantly impaired the turnover and remodeling rates of periosteal and endosteal bone. The fluorescent bands were distinct and wider in the control than in the experimental animals. Mean ratio values for labeled bone showed considerable variations in different regions and age groups. The amount of labeled bone in the condyle and molar region of control animals was 1.49 to 1.77 and 1.41 to 1.78 times higher than in the lathyritic animals.