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Promace day 1/MOPP day 8 chemotherapy for prolymphocytic leukemia: A case report of prolonged survival

The treatment result of a case of de novo B‐cell prolymphocytic leukemia (B‐PLL) is described. The diagnosis was established with histologic, ultrastructural and immunologic studies. The patient was treated with chemotherapy using a total of seven cycles of ProMACE Day 1/MOPP Day 8 lymphoma regimen. Complete remission was achieved after 5 cycles of chemotherapy. The patient remains disease free after a 7‐year follow up. This is the first case of PLL being treated with such a regimen and the only case reported achieved such prolonged survival. Results of other treatment modalities are reviewed. © 1994 Wiley‐Liss, Inc.