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Haemoglobin D Punjab in a Cuban family and its interaction with haemoglobin S.

A Cuban child carried 2 abnormal slow moving haemoglobins and suffered from severe haemolytic anaemia. Haematological studies of the family and chemical analysis of the abnormal haemoglobins indicated that he was a case of sickle-cell-haemoglobin D disease, which is produced by the interaction between Hb S and Hb D Punjab. This is the first case of Hb D Punjab found in Cuba. The clinical picture of the patient is discussed