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[Course of multiple sclerosis with and without corticosteroid therapy].

The course of multiple sclerosis in 186 patients had been studied at the Nervous and Mental Diseases Department - University of Padua - Italy. Among the 186 patients who have been followed, 93 have never been subjected to a corticosteroid oral therapy; the 93 other patients had undertaken an oral therapy with methyl-prednisolone. The seriousness of the course and the kind of evolution have been examined valuating the clinical observation. As regards the seriousness of the disease course, statistically significant differences between the two groups of patients have not been found. More considerable differences have been found for the kind of evolution.