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Palmoplantar Lichen Planus with Papular Oral Lesions: Case Report and a Brief Review of the Literature

ABS TRACT Lichen planus (LP) is a common inflammatory dermatosis with a chronic course which is typically characterized by small, violaceous, flat-topped polygonal papules mostly seen on the flexor aspects of the wrists, the lumbar region, and around the ankles. The etiopathogenesis has not been fully elucidated yet, however a T cell-mediated immune response to an antigenic stimulus is mostly favored. It has been proposed that LP is an outcome of an interaction between endogenous and exogenous factors. Microbial agents, metals, chemicals, and drugs are the most well-known exogenous antigenic factors in the induction or aggravation of LP. Besides the classical form, there are several other clinical variants of LP which are categorized according to morphology, configuration and distribution pattern of the lesions. Palmoplantar LP is a rare variant of LP, which is generally characterized by erythematous scaly plaques with a scaly peripheral collarette or diffuse hyperkeratotic yellow plaques similar in appearance to keratodermas. Herein, a case of toxicant-induced palmoplantar LP with typical cutaneous lesions and distinctive mucosal involvement is presented.