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Protective effects of Enterococcus faecium strain R30 supplementation on decreased muscle endurance under disuse in rats

What is the central question of this study? Does Enterococcus faecium strain R30 (R30), a new lactic acid bacterial strain for supplementation, attenuate shifts in the typology of whole muscle fibres from slow‐ to fast‐twitch by altering the autonomic nervous system in atrophied skeletal muscles? What is the main finding and its importance? R30 supplementation may attenuate the shifts in the typology of whole muscle fibres from slow‐ to fast‐twitch fibres by upregulating peroxisome proliferator‐activated receptor‐γ coactivator‐1α and activating the calcineurin–nuclear factor of activated T‐cells signalling pathway, thus ameliorating the decrease in muscle endurance associated with disuse.