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Hormone replacement therapy and breast cancer.

Hormone replacement therapy (HRT) leads to a similar annual increase in risk of breast cancer as does each extra year of remaining premenopausal. Taken for more than 10 years HRT leads to a 35% increase in risk of developing breast cancer. It does not increase a woman's risk of dying of breast cancer, and may improve the prognosis. Some breast cancer patients can safely take HRT and some formulations might reduce the subsequent risk of relapse.