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Evaluation of the Effects of Mozart Music on Cerebral Hemodynamics in Preterm Infants

Preterm infants, as a special population, exposed to the stimulus of medical procedures, need efficient integrated care. Music, a non-invasive positive stimulus, has the ability to improve infants well-being. In this study, a randomized controlled trial was conducted to evaluate the effect of Mozart music on cerebral hemodynamics detected by functional near-infrared spectroscopy (fNIRS). The statistical analysis results showed that the sample entropy of the experimental group was significantly lower than that of the control group in resting state after music intervention. It suggested that Mozart music could achieve the effect of calmness and relaxed state correlated with lower brain activities. This study will provide evidence to support the wide application of music intervention in clinical practice.