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Responses to reviewers' comments

Reviewer #1: The manuscript entitled with " Highly Specific and Sensitive Detection of Burkholderia pseudomallei Genomic DNA by CRISPR-Cas12a" submitted by Wongpalee et.al., presents a novel method that circumvents long time amplification issues by utilizing CRISPR-Cas12a coupled with isothermal amplification of a target DNA. Although the article has scientific rigor, few flaws need to be corrected before it can be considered for publication.