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Evaluation of antioxidant and antihyperlipidemic activity of extract of Garcinia indica.

Garcinia indica is well spread in tropical rain forest of Western Ghats of India. Extract of dried fruit rind of kokum was prepared using methanol. Extract was evaluated for antioxidant and antihyperlipidemic activity. Garcinia was tested for antihyperlipidemic activity using cholesterol induced hyperlipidemic model in Albino Wistar rats. It exhibited significant reduction in total cholesterol, triglycerides, LDL-C, VLDL-C levels and increase in level of HDL-C when compared to Lovastatin. Artherogenic index and LDL-C: HDL-C ratio was also reduced to significant extent. Significant antioxidant and antihyperlipidemic activity may be due to the presence of polyphenols like Garcinol and hydroxycitricacid in Garcinia. INTRODUCTION: Garcinia indica is well spread in evergreen tropical rain forest of Western Ghats of India from Kokan to Mysore. The dried outer rind