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The Increase of Brain Activity in Frontal Lobe After One Hour Methadone Intake

Narcotics is a very dangerous disease because it can damage the nervous system which change the abuser's personality becomes worse. Uncontrolled use of the drugs can lead to criminal acts, namely by destroying norms, public peace, and national security. Methadone is a synthetic opioid that is medically used as a substitution therapy for drug abusers. Giving doses must be done carefully to avoid the undesirable effect. So far, an instrument that can be used to help a medical treatment of doses methadone have not been found yet. In this study, an instrument for detection of drug effects on brain activity is developed and subsequently can be used as a tool for administering of methadone doses. To see the changes in the brain activity, an experiment is conducted in which the brain signals of 8 narcotics addicted subject is measured: just before, 10 minutes, and one hour after methadone intake. The results of data processing showed that the amplitude in the frontal lobe tended to increase for all subjects (except subject 3) after one hour of methadone intake are obtained.