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Torsade de Pointes in NIDDM With Long QT Intervals

Patients with diabetes are at an increased risk for sudden death (1). On the other hand, men with a long heart rate-adjusted QT interval (QTc) are at a higher risk for coronary heart disease and sudden death, even within the normal range of QTc in the general population (2). Sudden deaths in diabetic patients are attributed to circulatory failure and arrhythmia (3), the latter of which is difficult to diagnose. Recently, diabetic patients with prolonged QT intervals have been reported as prone to sudden death (4). We describe a diabetic man whose QTc lengthened substantially and who subsequently developed torsade de pointes, a fatal ventricular tachycardia (5).