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Effects of mood‐stabilizing drugs on dendritic outgrowth and synaptic protein levels in primary hippocampal neurons

Mood‐stabilizing drugs, such as lithium (Li) and valproate (VPA), are widely used for the treatment of bipolar disorder, a disease marked by recurrent episodes of mania and depression. Growing evidence suggests that Li exerts neurotrophic and neuroprotective effects, leading to an increase in neural plasticity. The present study investigated whether other mood‐stabilizing drugs produce similar effects in primary hippocampal neurons.