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The Development of the Liquid Cell Smear Device for Liquid-Based Cytology Test

This paper describes the development and validation of the liquid cell smears device for early cancer detection. In this study, the liquid cell smears device with the automated production of cell slides for Liquid-based Cytology Test has been developed. To validate the Liquid cell smear device, we used each 100 samples related to cervix, sputum, urine, body fluids, and thyroid. Experimental conditions were divided into five, which were the distance of the cylinder, the moving party's ascent and descent distance, and time to stop the smears. After staining, their verification was conducted through cytologic and histologic diagnosis. As a result, we found the optimal conditions to produce slide such as cervix(GYN) at the condition 2, sputum(SPUTUM) at the condition 4, urine(URINE) at the condition 5, body fluids(BODY FLUID) at the condition 1, and thyroid(FNA) at the condition 3. Therefore, it is suggested to be possible as cytologic and histologic diagnosis.