{'fraction_non_alphanumeric': 0.024291497975708502, 'fraction_numerical': 0.009446693657219974, 'mean_word_length': 4.936, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
A requirement for the CD5 antigen in T cell activation

Treatment of adult rats with a monoclonal antibody specific for the CD5 antigen led to a dramatic reduction in the number of CD5+ cells. However, a substantial number of T cells remained as assessed by other T cell‐specific antibodies. These CD5− T cells did not proliferate in response to alloantigen or mitogenic stimulation, did not generate cytotoxic T lymphocytes in vitro, and did not induce graft‐vs.‐host disease when injected into susceptible recipients in vivo. Re‐expression of the CD5 antigen occurred when CD5‐ T cells were placed in an environment devoid of the anti‐CD5 antibody. Re‐expression of the antigen was followed by return of the T cell proliferative responses.