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Therapeutic Hypothermia as Effective Therapy For ROSC Patients With Cardiac Arrest: A Systematic Review

Prehospital cardiac arrest is a relevant cause of death worldwide. The patients who can reach the ROSC (Return of Spontaneous Circulation) phase after experiencing cardiac arrest, only about 10% can experience improvement and are discharged from the hospital, in addition, only a small proportion can go home with neurological conditions back well. However, there are no studies that reveal when is the right time to implement therapeutic hypothermia, and whether therapeutic hypothermia measures are safe and effective for ROSC patients in cardiac arrest. This systematic review aimed to identify therapeutic hypothermia as a safe and effective action in post cardiac arrest patients and the appropriate time and temperature for the procedure. This research was taken from the electronic database PubMed, Science Direct, EBSCO, and Google Shcolar, through database scanning, and article screening was carried out independently by researchers. Researchers followed the requirements in fulfilling the inclusion criteria. We used all electronic search strategies for each electronic database according to inclusion data, with search strings: therapeutic hypothermia, prehospital, outof-hospital Cardiac Arrest, randomized controlled trials. Therapeutic hypothermia is safe and effective for use in ROSC patients with cardiac arrest and the right time to perform this action is at the pre-hospital time with the use of a temperature of 34-36 ° C. Therapeutic hypothermia can be performed pre-hospital with intravenous fluids at a temperature of 34-36 ° C after the patient is resuscitated or during resuscitation, thereby reducing neurological failure due to cardiac arrest.