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Development of a Compendium of Microcrystal Tests for Illicit Drugs

Microcrystal tests using polarized light microscopy (PLM) can identify most illicit drugs specifically and quickly, and they are inexpensive compared to other methods. “A Modern Compendium of Microcrystal Tests for Illicit Drugs and Diverted Pharmaceuticals” [1], recently published online by McCrone Research Institute, includes 19 drugs for which microcrystal tests using various reagents have been previously developed. This compendium describes in detail the microcrystals formed from each test and includes photomicrographs, morphology illustrations, optical properties, notes and infrared spectra of the microcrystals. An example page of the compendium is shown in Figure 1.