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Partners in enhancing functional ability and well-being.

In a philosophical essay published over 3 decades ago, Edmund Pellegrino1 posited that some “would define medicine as the negotiated outcome of the physician–patient relationship.” Today, we might include pharmaceutical and insurance companies as players at the bargaining table. This issue of Neurology ® Clinical Practice ( NCP ) examines the ongoing negotiation for better health outcomes in patients with chronic neurologic conditions.