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Serum Vitamin B12 Concentrations in the General Population: A Ten‐year Follow‐up

Summary. Community samples of 673 subjects who had had serum vitamin B12 concentrations measured in 1958 were followed‐up 10 yr later. 134 of these subjects had died; the death rates showed no consistent trend in relation to the original serum vitamin B12 concentrations. Comparisons of concentrations in 1958 and 1968 in 480 subjects showed correlation coefficients (r) of between 0.46 and 0.71 in various subgroups. The oldest age group had a slightly lower mean concentration, and a larger proportion of this group had values below 100 pg/ml. Several subjects with a consistently low serum vitamin B12 concentration for 10 yr maintained an apparently satisfactory circulating haemoglobin concentration.