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THE APPLICATION OF VASOPRESSIN FOR CORRECTION OF THE CONSEQUENCES OF THE INFLUENCE OF PSYCHOGENIC INJURY OF MOTHERS ON THE BEHAVIOR OF THE offspring

Vital stress (mental trauma) causes depressive-like elements in the behavior of rats and psychoemotional disorders in their offspring. Pups born to females after stress experienced a month before pregnancy are characterized by a depleted behavior structure, a decline in research activity, and a decrease in motor activity. The revealed violations in the psychoemotional sphere of mothers are stopped by injecting stressed females intranasally with 1-deamino 8-D arginine-vasopressin at a dose of 2·10-7 mg within 5 days after mental trauma. Course therapy with vasopressin in mothers contributes to the normalization of behavior in their one-month-old offspring.