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Ceftazidime in Gram-negative infections: three case reports.

Three patients with serious infections due to Gram-negative bacilli were treated with ceftazidime: a 52-year-old woman with Enterobacter cloacae meningitis, a 33-year-old woman with post-traumatic Pseudomonas aeruginosa mediastinitis and a 68-year-old man with myelomatosis and Ps. aeruginosa pneumonia. In all three cases the use of ceftazidime, in combination with gentamicin, resulted in clinical improvement associated with rapid clearing of the organism from infected sites. No haematological or biochemical abnormality attributable to ceftazidime was detected.