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Toxicology of carbon nanostructures. Part I. Spherical nanoparticles (fullerenes and nanoonions)

The literature review is devoted to the generalization of publications on the toxicity of carbon nanostructures, which have recently been increasingly used in biological and pharmacological research, in medicinal chemistry with the prospect of being used in medicine. Analysis of the literature data shows that, despite a huge amount of work, there are no unambiguous conclusions about the toxicological characteristics of various types of carbon nanomaterials. The use of carbon nanostructures in medicine can be questioned due to the potentially adverse health effects of their use. To clarify the harmlessness, it is necessary to develop more effective tests on animals, taking into account the characteristics of each type of nanomaterial.