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Does rotavirus mark the spot?

This patient has developed rotavirus-associated Mild Encephalopathy/Encephalitis with Reversible Splenial Lesion (MERS). MERS is a novel clinic-radiological syndrome first described in Japan by Salmi in 1978, that, among viral causes, has been commonly associated with Rotavirus. A transient splenial lesion with reduced diffusion that appears as a high signal intensity in diffusion-weighted MRI is the main diagnostic feature. The outcome of rotavirusassociated MERS is good, with the majority of patients achieving full recovery within 12 days irrespective of treatment. According to the diagnosis our patient clinical condition improved over the subsequent 5 days, with gradual resolution of his symptoms. The EEG performed 10 days after the admission was completely normal, followed by normal development without neurological sequelae and normal MRI at 3-months.