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A6091 Influence of Blood Pressure Control on the 10-year Risk of Stroke in Stroke-Free Nigerians with Arterial Hypertension

Objectives: Arterial hypertension remains the dominant risk factor for stroke globally. There is paucity of information on the risk of stroke in those with hypertension in Nigeria, despite the high burden of this modifiable risk factor. The objective of this study was to assess blood pressure (BP) control and its influence on the 10-year risk of developing stroke in adult Nigerians. Methods: Consecutively consenting stroke-free adults with arterial hypertension who were on follow up at the medical outpatient department of the University of Ilorin Teaching Hospital were recruited using a cross sectional design. An interviewer-administered questionnaire was used to obtain relevant information while blood pressure was measured using a mercury sphygmomanometer. All information was entered into the Stroke Riskometer® App to determine the 10-year risk of developing stroke. Good blood pressure control was defined as a BP < 140/ < 90 mmHg; binary logistic regression was used to determine the effect of BP control on the 10-year risk of developing stroke. Results: There were 333 respondents with a mean age of 58.85 ± 13.02 years; females 62.2%. Systolic and diastolic BP were 134.4 ± 17.3 mmHg and 84.0 ± 12.7 mmHg respectively. Poor BP control was present in 121 (36.3%) of the study participants. The mean 10-year risk of stroke was 10.56 ± 8.89%. Poor BP control was significantly associated with the 10-year risk of developing stroke (OR 1.041, 95% CI 1.015–1.068; p < 0.002). Conclusion: Blood pressure control is poor in about one-third of stroke-free hypertensives in this cohort. Efforts at improving BP control will be useful in reducing the 10-year risk of developing stroke in them.