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Methanol bioconversion by Butyribacterium methylotrophicum—batch fermentation yield and kinetics

Butyribacterium methylotrophicum is an anaerobic bacterium that can convert methanol to butyrate. This ability to produce longer‐chain carbon compounds from C1 substrates could be of commercial significance. The fermentation rates and product formation depend on the methanol/bicarbonate ratios during fermentation. The kinetics of batch fermentation fit the Luedeking‐Piret model with growth and maintenance associated product formation. Butyrate yield of 0.256 mol/mol methanol (ca. 85% of theoretical yield) has been obtained in batch fermentation.