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Reaction of phenobarbital with diphenhydramine.

Abstract A compound of low water solubility, consisting of pheno- barbital-diphenhydramine in a 1:1 ratio and mp 109.5-110.5° was isolated from a prescription which had been dispensed as a clear solution and later returned with a white sediment. The information obtained suggested that it was either an easily dissociated complex or a salt.