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Acariasis and Disrupted Sphincters

positive association between DM and colorectal cancer risk. However, clinical features of colorectal cancer complicated by DM remain unclear. Thus, we retrospectively evaluated malignant neoplasia, especially colorectal cancer, in 845 DM patients during 12 yr in a small island of Japan. The most frequent neoplasm was colorectal cancer (11 of 845), followed by gastric cancer (eight of 845), lung cancer (eight of 845), and pancreatic cancer (seven of 845). These 11 diabetic patients with colorectal cancer (seven men, four women; mean age 69 yr) were analyzed by colonoscopic findings. Indications for colonoscopy were: positive fecal occult blood tests in three patients, abdominal pains in two, bloody stool in one, anemia in one, constipation in one, abdominal fullness in one, bowel obstruction in one, and anal pain in one. One patient had two synchronous lesions; hence, a total of 12 adenocarcinoma were found. Of the 12 adenocarcinomas, nine (75%) were detected in the rightsided colon, markedly higher than three (25%) in the leftsided colon. Endoscopic findings demonstrated three early carcinomas of sessile types and nine advanced carcinomas. Histological findings showed seven well-differentiated adenocarcinomas, four moderately differentiated adenocarcinomas, and one mucinous adenocarcinoma. In conclusion, our preliminary data suggest that the frequency of rightsided colon cancer increases with diabetic patients. Total colonoscopy should be indicated in DM patients for colorectal cancer screening. Further studies comparing DM patients with non-DM patients for this frequency are needed.