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[Fibronectin and the phagocytic activity of the neutrophilic granulocytes in patients with different clinical variants of bronchial asthma].

A study of 125 cases of bronchial asthma revealed low contents of fibronectin. The degree of the decrease depended on the severity of the clinical course of the disease and treatment with glucocorticoid hormones. Patients with bronchial asthma showed an essential reduction of the number of neutrophilic granulocytes capable of phagocytosis. In the process of incubation of polynuclears with fibronectin occurs restoration of their phagocytic activity which was less pronounced in patients receiving glucocorticoids.