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[Insulin resistance model induced by dexamethasone in rats].

AIM
To build a easy and reliable rat model of insulin resistance.


METHODS
Changes concerning sugar metabolism were observed in experimental rats injected intraperitoneally by different doses of dexamethasone.


RESULTS
The changes by dexamethasone in fasting blood insulin and insulin resistance prior to that of fasting blood glucose were dose and time dependent.


CONCLUSION
It was convenience to set up a insulin resistance model induced by dexamethasone in rats which would favor other related research.