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Spinal Ganglioneuroma in a Steer

A 10-month-old Hereford steer was presented to New Bolton Center with a 4-day history of progressive posterior paresis. At admission there was complete flaccid paralysis of both hind legs. Caudal to the second lumbar vertebra, reflex response and conscious response to skin pinprick was reduced. A weak patellar response was present. Serum electrolytes and hemogram were normal. The animal was killed with an overdose of sodium pentobarbital and necropsied. The only abnormality was a pale tan, oval, 2 x 3 cm mass bulging from the dorsal surface of the first lumbar segment of the spinal cord. On cut surface it extended into the cord as a wedge with its apex at the central canal (fig. 1). Sections of cord were fixed in 10 buffered formalin, imbedded in paraffin, and cut at 10 pm. The sections were stained with hematoxylin and eosin, Masson’s trichrome, luxol-fast blue, and Voigt’s nerve stain. The mass was well delineated by a fine fibrous tissue band that compressed the cord but did not infiltrate the parenchyma. The predominant