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The allantoic membrane of the rabbit: Evidence of a cholinergic electrical potential

The electrical potential of the rabbit allantoic membrane is sensitive to acetylcholine, a sensitivity which can be altered or abolished by anticholinesterase compounds. Biochemical and histochemical studies indicates that acetylcholinesterase activity is present in the endodermal layer of the membrane. These findings suggest that the allantois may be a valuable model for investigations into the role of acetylcholinesterase in membrane excitability.