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Bacterial contamination of single‐donor blood components

SUMMARY. An analysis was performed of the microbiological laboratory quality control data for the past 9 years (1985–1993). Bacterial contamination was detected in 100 of 25,171 tested blood components. Single‐donor platelet concentrates had a contamination incidence of 25 in 5889 (0.42%); whole blood samples were contaminated at a rate of 1 in 2973 (0.03%) and red cell concentrates at a rate of 73 in 15, 317 (0.48%); of 992 samples of fresh frozen plasma only 1 was contaminated (0.1%). Gram‐positive staphylococci comprised 75% of cases and Gram‐negative rods 10%. This frequency of laboratory‐detected bacterial contamination contrasts with the low rate of transfusion‐associated septicaemic events.