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RE: net risk reclassification P Values: valid or misleading?

Biomedical research of the last few decades has been characterized by an overreliance on statistical testing. Researchers like many zeros in their P values to convince their audience on the validity of their claims from empirical observations. The area of predictive modeling has been no exception. When the focus shifted from association, eg, expressed by hazard ratios, to the added predictive ability of new biomarkers, P values remained at the forefront in reporting. A contributing factor is the difficult