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One-year results of a prospective multicenter study of the Casebeer system of refractive keratotomy. Casebeer Chiron Study Group.

PURPOSE
To evaluate the clinical results, predictability, stability, safety, and the patient satisfaction after refractive keratotomy for the correction of myopia and astigmatism using a defined protocol (the Casebeer system).


METHODS
The authors enrolled 324 patients (615 eyes) in a prospective study conducted by 18 surgeons. All procedures were performed using ultrasonic pachymetry with the diamond knife blade set at a length of 100% of the temporal paracentral corneal thickness reading and four to eight centripental (Russian style) incisions with or without fixation of the globe. Straight transverse incisions were done for astigmatism in 222 (36%) eyes. One to eight repeated operations (enhancements) were done on 241 (39%) eyes.


RESULTS
Mean baseline cycloplegic refraction was -3.68 +/- 1.59 diopters (D) (range, -0.88 to -8.25 D). One-year data were available for 546 eyes (89%). At 1 year, mean spherical equivalent cycloplegic refraction was -0.27 +/- 0.78 D (range, -3.13 to +3.00 D). There were 373 (68%) eyes with a refraction of +/- 0.50 D, and 483 eyes (89%) within +/- 1.00 D of emmetropia. Ten eyes (2%) were overcorrected by more than 1.00 D. Mean baseline refractive cylinder was 1.01 +/- 0.75 D (range, 0-5.75 D); at 1 year, the mean cylinder was 0.40 +/- 0.55 D (range, 0-2.50 D). Uncorrected visual acuity was 20/20 or better in 297 (54%) eyes and 20/40 or better in 93%. Six eyes (1%) lost two to three lines of spectacle-corrected visual acuity; the worst visual acuity was 20/30. Of patients responding to a standardized questionnaire, 320 (77%) wore no spectacles for distance or near vision; there was a significant increase in glare and fluctuation of vision from baseline; and 247 (90%) were very satisfied with the outcome.


CONCLUSIONS
Refractive keratotomy using radial incisions with or without transverse incisions and following the Casebeer system effectively reduces and often eliminates myopia and astigmatism with a high degree of safety. Enhancement surgery was required in 39% of eyes. Glare and fluctuation of vision increased postoperatively but were rated mild, and patient satisfaction was high.