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Significant Deviation in the Configuration of Tandem Repeats in Prokaryotic Genomes

Various studies of whole-genome duplication (WGD) have been done on eukaryotic genomes, and WGD as well as gene duplication is being thought to be one of the important processes in genome evolution for some eukaryotic lineages such as yeast, fishes, and vertebrates [4]. As for prokaryotic species, however, only a few studies onEscherichia coli[2, 5] andAnabaena[3] have been reported. Furthermore, the former two studies had been performed before the genome was completely sequenced. In this study, we seek the evidences of WGD on completely sequenced prokaryotic genomes based on methods of bioinformatics and statistical analysis.