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Attention deficit hyperactivity disorder

objective: This study was undertaken to assess whether the diagnosis of attention deficit hyperactivity disorder (ADHD) is retained from childhood into adulthood. Method: A search of the literature yielded nine prospective studies in which cohorts ofchildren with the disorder were formed and then reexamined 4-16 years later to determine the level ofretained ADHD. The resulting data were subjected to nonlinear regression analysis to ascertain the relationship with chronological age. Results: The data followed an exponential decline over time to a high degree of accuracy. Conclusions: The rate of A DHD in a given age group appears to decline by 50% approximately every S years. Ifa prevalence ofADHD in childhood of4% is assumed and the exponentialdecline extrapolated, the estimated rate ofadult ADHD ranges from about 0.8% at age 20 to 0.05% at age 40. (AmJ Psychiatry 1996; 153:1143-1146)