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[Distribution of hepatitis B virus genotype B subgenotype in China].

OBJECTIVE
To investigate the distribution of hepatitis B virus (HBV) genotype B subgenotype in China.


METHODS
A cohort of 511 patients with chronic HBV genotype B infection, collected from 7 centers across China, were analyzed by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) or nucleotide sequencing.


RESULTS
For the 511 patients, only subgenotype Ba was identified and subgenotype Bj was not found.


CONCLUSION
In China, subgenotype Ba was the most prevalent HBV strains, while subgenotype Bj was very rarely found.