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HematoWork: A Knowledge-based Workflow System for Cancer Therapy

The domain of hemato-oncology is characterized by a complex patient management and the involvement of several institutions (e.g. oncological ward, private practitioner, external review panels) in the context of protocol-directed trials. Current research efforts in this domain (e.g. [1-3]) focus on specialized subtasks such as chemotherapy dose calculation and toxicity monitoring, but fail to support inter-application data flow and coordination aspects which have been identified as essential for integration in heterogeneous and distributed clinical environments (e.g. [4,5]). At the University of Leipzig, we are presently developing the distributed workflow system HEMATOWORK, which has explicit knowledge about the intended oncological treatment strategy and the associated communication paths between the involved institutions. In particular, HEMATOWORK intends to support the following basic tasks: