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Clinical Research Nurses' Expectations and Realities of their role: A Qualitative Evidence Synthesis.

AIMS
To synthesise the available body of qualitative studies relating to clinical research nurses' experiences of their role.


METHODS
A systematic search of the literature in five databases was undertaken: CINAHL, Medline, Embase, Pubmed, Proquest. Thomas and Harden's three-stage approach to thematic analysis was followed using the ENTREQ statement for reporting.


RESULTS
Nineteen studies reported in 20 papers (with a total of 232 nurses) were included in the synthesis. Three analytical themes with six subthemes were identified: 'identity; 'meeting targets' and 'patient advocate'.


CONCLUSIONS
Clinical research nurses experience isolation and contributing to this is their perception of non-research nurses' lack of understanding for their role. This can result in difficulties when recruiting study participants. Clinical research nurses can experience internal conflict between being a patient advocate and adhering to a trial protocol.


RELEVANCE TO CLINICAL PRACTICE
Training is needed to help research nurses develop skills to face challenges in order to ensure safe and ethical care is provided to research participants whilst also ensuring high quality data collected for the study.