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Preliminary Phytochemical Investigation and in vitro Evaluation of Anthelmintic Activity of Pergularia extensa

The main objective of the present study is to screen the presence of different phytoconstituents present in various extracts of the whole plant of Pergularia extensa. These phytoconstituents were analysed by thin layer chromatography (TLC) by spraying suitable reagents which showed the pertinent intensity of the colour determining the significant phytoconstituents. Different concentrations (10, 20 and 40 mg/ml) of various extracts had been investigated in the bioassay using albendazole as reference drug to determine the time of paralysis and death of the worms. The benzene extract showed more potent found not only to paralyse but also to kill the worms.