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Positive hepatitis B virus core antibody in HIV infection—false positive or evidence of previous infection?

Isolated HBV core antibody (anti‐HBc) is defined as the presence of anti‐HBc with a negative HBV surface antigen (HBsAg) and HBV surface antibody (anti‐HBs <10 IU/l). In patients infected with HIV with isolated anti‐HBc, the aim was to determine: The prevalence of isolated positive anti‐HBc; The most effective method of identifying which patients have had previous Hepatitis B Virus (HBV) infection; The prevalence of false positive anti‐HBc.