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Group B Streptococci serotype distribution in pregnant women in Ghana: assessment of potential coverage through future vaccines

Group B streptococcal (GBS) colonization of pregnant women can lead to subsequent infection of the new‐born and potentially fatal invasive disease. Data on GBS colonization prevalence and serotype distribution from Africa are scarce, although GBS‐related infections are estimated to contribute substantially to infant mortality. In recent years, GBS vaccine candidates provided promising results in phase I and II clinical trials. We aimed to assess the prevalence and serotype distribution of GBS in Ghana since this knowledge is a prerequisite for future evaluation of vaccine trials.