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Pulsed Radiofrequency Neuromodulation Contributes to Activation of Platelet‐Rich Plasma in In Vitro Conditions

Recent years have brought new developments in interventional chronic pain management, namely regenerative orthopedics utilizing platelet‐rich plasma (PRP) as well as further evolution of pulsed radiofrequency neuromodulation (PRF). Both methods have been used separately. Here, we investigated whether PRF may potentiate the activation of platelets in PRP samples when both these techniques are combined together in in vitro conditions.