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Audit of outcome of super-accelerated hepatitis B vaccination schedule in a genitourinary medicine clinic.

An audit of outcomes from the first year of implementation of a super-accelerated hepatitis B vaccination schedule was performed. One hundred and sixteen patients commenced vaccination for hepatitis B in the study period. All notes were located and reviewed. In all, 72.4% of patients completed three vaccinations compared with 61.5% in an earlier period using the old schedule. Serological response for 39 patients was measured at approximately 12 weeks post commencement of vaccination. Of these 69.2% had mounted some serological response, 48.7% a good response. As expected, a faster vaccination schedule improves completion rates for the first three injections. Early serological responses are encouraging and comparable to published data for new schedule vaccination responses at 12 weeks. It is anticipated that serological response will continue to improve over the year before a booster dose of hepatitis vaccination is due.