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[A study on the infiltration of macrophages and lymphocytes in interrenal tissues in patients with acute renal tubulointerstitial disease].

Renal tissues of 14 patients with acute renal tubulointerstitial disease were studied by using immunohistochemical method. Cells infiltrated in interrenal tissue were observed. The results show that the causes which result in acute renal tubulointerstitial disease are different; the renal tubular and interstitial damages are reversible or irreversible; the major inflammatory cells infiltrated in interrenal tissues are CD68 and CD45ro positive cells. The results suggest that the macrophages and T lymphocytes infiltrated in interrenal tissues play an important role in the progress of acute renal tubulointerstital disease.