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HIV infection in Tirupati, India.

It was with interest that we read the letter by Daniels et al,' concerning the heterosexual transmission of hepatitis B virus (HBV) and its acquisition abroad. It is widely accepted that homosexual and bisexual men attending genitourinary medicine clinics may have a high prevalence of serological markers though the difficulty in screening and immunising this risk group was shown by an interesting audit.2 However, vaccination of these risk groups in areas of low endemicity has been found to be ineffective in reducing the overall rates of infection. As highlighted in the letter, there is a need for