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Do Statins Decrease the Arrhythmia Burden in Patients with Paroxysmal Atrial Fibrillation?

This was a prospective randomized trial of 106 patients who had an atrial based pacemaker therapy initiated for significant bradycardia. Fifty-two patients (23 males, 70 +/13 years old) were randomized to the statin group (atorvastatin 20 mg/d) and 54 (25 males, 72 +/13 years old) to the non-statin group. The effect of atorvastatin on time to the first attack of AF or AHE (> or =180 per minute and > or =1 or 10 minutes), which was accurately detected by pacemaker interrogation at 1,3,6 and 12 months of follow-up.