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Effect of exposure misclassification on the mean squared error of population attributable risk and prevented fraction estimates

Previous work has considered the effect of exposure misclassification on the bias of population attributable risk (AR) estimates, but little is known about the corresponding effects on their precision or mean squared error (MSE). This paper considers AR estimation in typical scenarios for case–control and cohort studies. The analogous index used when exposure reduces the risk—the prevented fraction (PF)—is also investigated.