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Surgical Invasion Evoking Nociception and Postoperative Complications

are associated with severe postoperative complications. On the other hand, general anesthesia sup-presses nociception. Nociception monitoring under general anesthesia estimates a quantified balance between nociception and anti-nociception by using variables evoked by autonomic responses or in the electroencephalogram. A nociception monitoring value during surgery has the potential to be an objective indicator of surgical invasion.