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P32: A NOVEL IMMUNOTHERAPEUTIC VACCINE TO MODULATE CYTOKINE RESPONSES OF ANTIGEN‐SPECIFIC CD4+ T CELLS IN PEANUT ALLERGY

Results: Five patients were found to have positive goat’s milk and/or sheep’s milk sIgE. Two out of the 5 patients had evidence of crosssensitisation to cow’s milk and were cautioned to avoid all dairy products. All 5 sIgE+ patients had a history of severe anaphylaxis to either goat’s cheese, sheep’s cheese or feta with at least 1 life threatening feature (hypotension, tongue or throat angioedema, difficulty breathing). All patients identified had inflammatory skin conditions (either Eczema or Psoriasis) and had been using goat’s milk soap and/or moisturiser as a topical treatment. Three out of 5 patients had evidence of atopy with comorbid allergic rhinitis, asthma or both. Most patients had a significantly elevated total serum IgE, with an average level of 365 kUA/L.