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[Concentration of prolactin in the plasma of schizophrenic patients with positive and negative symptoms].

Two groups of schizophrenics receiving no neuroleptics for 12 months were examined. The first group was composed of 4 patients whose status was characterized by the predominance of positive symptoms (hallucination, etc.), the second of 9 patients with negative manifestations of the disease (social alienation, etc.). Prolactin levels were radioimmunoassayed in blood samples taken between 7 and 9 o'clock in the morning at different days in the same patient. Blood prolactin concentrations were significantly higher in the Group I patients (p less than 0.05).