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Update on protocols for fixe-timed artificial insemination in sheep

Fixed–time artificial insemination (FTAI) in cattle has had a marked growth in
 South American countries in the last two decades, mainly based in the use of
 pharmacological treatments with estradiol and progesterone. To improve the pregnancy
 rate obtained with this technology, the focus has recently been on other aspects of the
 hormonal protocols that had not been considered previously. The most novel approaches
 propose studying preovulatory strategies to improve postovulatory conditions to improve
 pregnancy outcomes. In this paper we review the main results obtained by extending the
 proestrus length (i.e., the interval from progesterone removal to insemination). The
 results show that these new approaches allow an improvement in pregnancy rate, which
 deserves to be taken into account to be included in the implementation of FTAI
 programs.