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[Thymus target cells subject to the regulatory effect of macrophages during the formation of graft-versus-host reaction effectors].

The data are provided on the interaction of macrophages with different thymocyte subpopulations during the formation of T cells entering the graft-versus-host reaction (GVHR). The intensity of the local GVHR was evaluated from the index of lymph node enlargement. The cortisone-sensitive, relatively radioresistant cells lying in the thymus cortex and migrating to the spleen have been demonstrated to serve as targets for the regulatory effect of macrophages. On the basis of a complex of the characteristics these cells have been identified as T1 cells.