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Facial Plastic and Reconstructive Surgery

(38 men, 42 women; median age, 61 years). A minimum follow-up period was set to be >1 year. The maximum standardized uptake value (SUVmax) was calculated for the primary tumor of PTC on the workstation (PETSTAT Viewer version 2.2). Receiver-operating characteristic (ROC) analysis was performed to determine the cutoffs to differentiate disease control with the relapse as the gold standard. The Cox proportional hazard model was used in the univariate and multivariate comparisons, and an estimated hazard ratio (HR) with 95% confidence interval (95% CI) was presented. Results: SUVmax of primary tumor ranged from 2.1 to 32.0 (median, 8.5). ROC analysis revealed pretreatment SUVmax to be a good parameter to determine relapse after surgery (area under the curve, 0.76). A cutoff of SUVmax 11.0 yielded the sensitivity, specificity, positive predictive value, and negative predictive value of 71%, 74%, 21%, and 96%, respectively. Patients with high (≥11.0) SUVmax had significantly worse relapse-free survival (P < .01) as compared with patients with low (<11.0) SUVmax. SUVmax was identified as a significant prognostic factor for relapse-free survival by both univariate (HR, 9.93; 95% CI, 2.09-70.34; P < 0.01) and multivariate (HR, 22.64; 95% CI, 3.61-241.00; P < 0.01) analyses. Conclusions: SUVmax on pretreatment FDG-PET was demonstrated to be a significant prognostic parameter for relapse in PTC receiving surgical resection.