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Utility of Quantitative Assessment of Regional Cerebral Blood Flow with 123I‐IMP SPECT: Diffuse Cerebral Hypoperfusion in Medicated Epileptic Patients

In the present study, we assessed the absolute values of regional cerebral blood flow (rCBF) in epileptic patients receiving chronic high dose antiepileptic drug therapy in comparison with those in normal volunteers matched for sex and age to examine the presence of rCBF abnormalities in such highly medicated patients. The present study focuses on the utility of the quantitative assessment of rCBF for clinical epilepsy.