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Separation of Perfusion Signals from Diffusion‐Weighted Image Series Enabled by Independent Component Analysis

An important task in diagnostic imaging of acute ischemic stroke is to identify the so‐called diffusion‐perfusion mismatch area. We aimed to investigate the possibility of facilitating the identification process by combining independent component analysis (ICA) and diffusion‐weighted MRI (DWI), with the expectation that this would eliminate the need for additional perfusion imaging to delineate perfusion lesion.