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A new era in lung transplantation: an individualized approach to donor lungs.

Since the first successful lung transplantation (LTx), performed in Toronto in 1983, there have been many technical advances. What was initially a daring endeavor has now become a routine procedure in the treatment of patients with end-stage lung disease. Despite advances in surgical techniques and patient management, one major obstacle continues to hinder the widespread success of LTx: the supply of quality donor lungs is insufficient to meet the growing demand, an increasing number of patients being in need of this life saving procedure. Currently, most donor lungs from multi-organ donors are deemed to be “too damaged” to be transplanted and are simply rejected. (1) Transplant surgeons