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Endogenous Bacterial and Fungal Endophthalmitis

Endogenous endophthalmitis (EE) occurs as the result of hematogenous spread of organisms to the eye. Today, it remains a diagnostic and therapeutic dilemma because of relatively infrequent occurrence and the need for prompt identification and therapy to obtain a positive outcome. Standardized guidelines for diagnosis and treatment remain elusive because of insufficient incidence to allow establishment of conclusive clinical trials. This paper presents a review of bacterial and fungal EE with a view of determining where we currently stand in terms of diagnosis and management of this condition.