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IAP Task Force Report: management of enteric fever in children.

Since 1990s Salmonella typhi has developed resistance simultaneously to all the drugs used in first line treatment (chloramphenicol, cotrimoxazole and ampicillin) and are known as Multi Drug Resistant typhoid fever (MDRTF). There are some reports of reemergence of fully susceptible strain to first line drugs(2). But these reports are few and unless antibiotic sensitivity testing shows the organisms to be fully susceptible to first line drugs they are not advocated for empirical therapy in typhoid.