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Orpin and its isoform are novel putative calcium binding proteins associated to intestinal and nerve regeneration in the sea cucumber Holothuria glaberrima (651.22)

Holothuria glaberrima exhibits the capacity to regenerate body parts after injury or loss. This ability is mediated by an initial blastemal formation which requires proliferation and reorganization of precursor cells. Accordingly, various molecules play key roles in different aspects of the regeneration of a body part. The use of microarrays and high‐throughput sequencing lead our laboratory to identify a series of new molecules associated to different processes of regeneration. Such is the case for the protein Orpin.