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The infection rate of hepatitis C virus in Chinese patients with type 2 diabetes mellitus

Objective To clarify the role of hepatitis C virus(HCV) infection in the pathogenesis of diabetes mellitus(DM).Methods The highly sensitive third generation detection kit was used to test anti-HCV in 533 patients with type 2 DM(group A),285 healthy people(group B),and 862 non-diabetic patients who had no defined chronic hepatic diseases(group C).Statistical analysis was performed by the Student′s t-test for continuous variables and Fisher′s exact test for categorical data.Results There were no significant differences in positive rates of anti-HCV among groups of A,B and C(1.31%,0.70% and 0.58%)(P0.05).HCV infection in diabetic patients was related to the age,DM duration,and history of surgical procedures(P0.01).There was no significant difference in the changes of liver function between the patients with type 2 DM combined with HCV infection and those with HCV infection alone.Conclusion HCV infection plays little role in the pathogenesis of type 2 DM in Chinese patients and it is not necessary to routinely test HCV in DM.