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Acute urethral syndrome in women

noted in previous studies of progesterone administration by various routes.2 Whitehead's group studied plasma concentrations, not the activity of the compound, and pointed out that "further studies are needed to determine the end-organ response and therapeutic efficacy." Despite the interesting possibilities raised by their work it was not perhaps ready to challenge the accepted view of progesterone metabolism that was summarised-perhaps too succinctly-in the words quoted by Mr Godfrey.-ED, BMJ.