{'fraction_non_alphanumeric': 0.016981132075471698, 'fraction_numerical': 0.0018867924528301887, 'mean_word_length': 5.9868421052631575, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Pathogenetic Aspects of IgA Nephropathy

IgA nephropathy (IgAN) is a common worldwide primary glomerulonephritis whose etiology and pathogenesis have remained unresolved. This particular form is defined by diffuse glomerular mesangial deposition of IgA and, less frequently and less intensely, IgG, IgM and C3. Immune deposition is accompanied by focal or diffuse mesangial proliferation, and the consequent chronic glomerular inflammation is further associated with sclerosis and variable loss of glomerular and tubular function.