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Quantifying cumulative anticholinergic and sedative drug load among US Medicare Beneficiaries

Medications with anticholinergic and sedative properties are widely used among older adults despite strong evidence of harm. The drug burden index (DBI), a pharmacological screening tool, measures these properties across drug classes, and higher DBI drug exposure (DBI > 1) has been associated with certain physical function‐related adverse events. Our aim was to quantify mean daily DBI drug exposure among older adults in the United States (US).