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Eye movements in acquired immunodeficiency syndrome.

To the Editor. —We read with interest the report by Currie et al 1 on eye movement abnormalities in the acquired immunodeficiency syndrome dementia complex. We recently had the opportunity to examine the eye movements of two patients with this syndrome. Report of Cases. —Case 1.—A 35-year-old man with 17 years' education was rated as having moderate neuropsychological impairment from acquired immunodeficiency syndrome dementia complex. Magnetic resonance imaging showed diffuse cortical atrophy and mild cerebellar hypoplasia. Case 2.—A 38-year-old man with 13 years' education was rated as having significant neuropsychological impairment due to acquired immunodeficiency syndrome-related complex. Magnetic resonance imaging showed mild enlargement of the vermian sulci and the lateral and third ventricles. The neuropsychological assessment was based on standard protocol. Eye movements were recorded using infrared oculography. Comment. —Both patients demonstrated fixation abnormalities consisting of saccadic intrusions of 1 to 3 degrees ("square-wave jerks") in clusters of two