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Endothelial inclusions in dermatomyositis.

Abnormalities of the microvasculature of muscle from patients with polymyositis have been reported by Gonzilez-Angulo, Fraga, and Mintz (1968). These changes were similar to those of systemic lupus erythematosus (SLE) and scleroderma (Norton, Hurd, Lewis, and Ziff, 1968). Although the nature of the vascular injury is unknown, the capillaries of active lesions of SLE have recently been shown to contain characteristic endothelial inclusions (Gyorkey, Min, Sinkovics, and Gyorkey, 1969; Norton, 1969). The present report describes the occurrence of similar inclusions in skin and muscle of dermatomyositis. Attempts to define the nature -of the inclusions are described and their possible