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[Study of relative factors which influenced the embolic level of microspheres in the hamster lingual carcinoma].

OBJECTIVE
To study the relative factors which influence the embolic level of microspheres in the hamster lingual carcinoma.


METHODS
Micropicture analysis instrument was used to measure the embolic level of microspheres which were poured through ascending aorta.


RESULTS
The optimum pressure of embolization was 30 kPa. The embolic level approached to remote site of the lingual artery as tongue cancer developed. In early invasive cancer period, the embolic level of microspheres was at arteriole level where microspheres block "the total values" which controlled the tumor microcirculation. The optimum embolic result and less offshoot microcirculation were obtained at this time. When in later period, microspheres mainly embolized the meta-arteriole. As the microvessels dilated, the dose of microspheres must be increased to get the best embolic result.


CONCLUSION
The experimental data for clinical choice of optimum pouring pressure, optimum opportunity and optimum cases.