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Predicting when children with progressive renal disease may reach high serum creatinine levels.

A method for predicting when children with progressive renal disease may reach high levels of serum creatinine (SC) was recently described in this journal.1 The authors did not seem to be aware that the same technique, ie, plotting the reciprocal (1/SC) or the logarithm (log SC) vs time has been tested in two slightly larger series of pediatric patients and was published some time ago.2,3 I agree that the reciprocal plot (1/SC vs time) is, in general, more appropriate than the semilog plot in predicting when a critical concentration of SC, say 10 mg/100 ml, may be reached.