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Heterogeneous State Cannabis Policies: Potential Implications for Patients and Health Care Professionals.

As of November 2021, cannabis has become legalized for medical purposes in 36 states and the District of Columbia. Eighteen states also authorize nonmedical use of cannabis by adults. The rapid expansion of access to cannabis has coincided with increased use across a number of demographic groups. In 2019, an estimated 48 million people in the US reported using cannabis, a 60% increase from 2002.1 Among adults aged 65 years and older, the prevalence of cannabis use increased 10-fold between 2006 and 2018, from approximately 0.4% to more than 4%.2 Yet amid the increasing availability and use of cannabis nationwide, regulatory policies and sources of information for patients remain fragmented and inconsistent. Approximately 10% of adults who use cannabis report using this drug primarily to treat a medical condition.3 However, few reliable resources are available for patients and clinicians to facilitate evidencebased discussions about the effects of cannabis on health. An information vacuum created by limited public health messaging and restrictions on research has been filled instead by advertising campaigns, anecdotal information, and improvised health policy, which may