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History of migraine treatment.

The history of the treatment of headache in general, and migraine in particular, spans the millennia, from the Neanderthal era to the Space Age. Beginning with a magical hypothesis of the cause of headache, which spawned a magical therapy, rational treatment for this ancient complaint evolved slowly and tortuously. Now, in the age of molecular medicine, a knowledge of where headache treatment began, and how it got to its current stage, aids in the continuing quest for the safe, effective treatment of migraine.