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Proliferative fibroblastic lesions. From hyperplasia to neoplasia.

It is rare to find a pathologist whose ideas and beliefs are so sound and pervasive as to influence our thinking decades after his writing. Yet such was the case with Dr. Stout, to whom we owe our basic classification of fibroblastic tumors, our concept of fibromatosis, and our diagnostic approach to fibrosarcomas. We need to continue the progress Dr. Stout made in these areas and to search for biochemical and molecular differences in these tumors with the hope that this knowledge will lead to new avenues for therapy.