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Perianal Condyloma Acuminatum in an Infant

A boy had been developing warts around the anus for the past 2 months. There was no history of genital or extragenital warts in the family members, ie, mother, father, and elder sister. Examination revealed a well-nourished baby weighing 5.7 kg, with small (2-6 mm), moist, friable warty lesions in the perianal region (Fig. 1). There was no inguinal lymphadenopathy. Proctoscopy revealed normal epithelium. No other skin or mucous membrane lesion was observed. Examination of the parents and sister did not reveal genital or extragenital warts. Blood VDRL was nonreactive in the infant, mother, and father. Histopathologic findings were compatible with the diagnosis of warts. After applications of 20% podophyllum, the warts disappeared completely in about 3 weeks.