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Rise in High-Density Lipoprotein-Cholesterol in Some Patients Treated with CAPD

Continuous ambulatory peritoneal dialysis (CAPD) has emerged as a practical and effective approach to the treatment of renal failure (I, 2). Indeed, CAPD has introduced a new era in the therapy of end-stage renal failure (2) .A significant increase in the incidence of cardiovascular complications, including coronary heart disease, occurs in patients with chronic renal failure (3). When such patients are treated with maintenance hemodialysis, cardiovascular complications persist as the major contributors to morbidity and mortality (4). While multiple cardiovascular "risk factors", notably hypertension, are undoubtedly operative, dyslipoproteinemias are frequently present in both untreated patients and those on maintenance dialysis (5). Elevated very-Iowdensity lipoprotein (VLDL)-triglyceride and decreased high-density lipoprotein-cholesterol (HDL-C) are the most common lipoprotein abnormalities. Depressed HDL levels confer a strong atherogenic potential (6), while