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Early thrombogenesis after aortic anastomosis by microvascular technique in rats.

This experimental study was undertaken to explore the histological analysis of early thrombogenesis after aortic anastomosis. One hundred and fifty ab dominal aortas of rats, measuring 1.2 to 1.5mm in diameter were transversely severed half way and vascular anastomosis was performed, using 10-0 monofila ment nylon interrupted suture. After fixation with 2.5% buffered glutearaldehyde the specimens were analyzed at 3, 5, 7, 10, 15, 20 and 30minutes after anas tomosis under light-microscope. The following results were obtained. Thrombi formed in about half of the specimens 3 to 15minutes after anastomosis. The thrombi reached maximum size at 7 minutes after anastomosis, then gradually decreased in size and completely disappeared at 30minutes.