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Molecular Imprinted Polymer Based Impedimetric Sensor for Trace Level Determination of Digoxin in Biological and Pharmaceutical Samples

DOI: 10.2174/1573411013666171117163609 Abstract: Background: Molecularly imprinted polymers (MIPs) are used as artificial receptors in biosensors for the detection of a wide range of analytes from small drug molecules to large molecular weight biomolecules. Quantification of Digoxin (DIG) in human serum and pharmaceutical samples has very high importance due to its low margin of safety. In this report, a highly sensitive molecularly imprinted polymer for DIG is prepared and the detection of analyte was conducted using electrochemical impedance spectroscopy.