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Clinical characteristics of chlamydia trachomatis respiratory tract infections in young infants in South Korea

Purpose: Chlamydia trachomatis ( C. trachomatis )is the most prevalent etiology of sexually transmitted diseases and also a cause of respiratory infections in infants. The purposes of this study were to determine the epidemiology, presentation, and laboratory findings of C. trachomatis respiratory infection, and to investigate it9s severity and hospital courses. Methods: Between February 2002 and January 2010, we enrolled infants younger than 6 months admitted to the Gil Hospital with the diagnosis of acute bronchiolits and pneumonia. Clinical findings and demographic data were reviewed in all patients. Basic laboratory examinations included white blood cell and eosinophil count. C. trachomatis was detected via enzyme immunoassay for the detection of C. trachomatis specific immunoglobulin M. Results: Of 1,708 patients, C. trachomatis was detected in 142 (8.3%). The incidence had increased from 2002 to 2009 and was higher in the spring. C. trachomatis was distinguished by less fever( P P P =0.01) Severity and clinical course of C. trachomatis infection was similar to the infections with the other etiologies. Conclusions: C. trachomatis is prevalent among infants younger than 6 months with the diagnosis of acute bronchiolits and pneumonia. We must consider C. trachomatis as the etiologic agent in infantile respiratory infections and must make more effort to detect C. trachomatis .