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Surgical site infection and antibiotic prophylaxis in mesh repair open inguinal hernia

To study surgical site infection and effect of antibiotic pro phylaxis in mesh repair of inguinal hernia. Comparative study. Department of Surgery, Liaquat University of Medical and Health Sciences Hospital, Jamshoro/Hyderabad from March 2011 to July 2013. One hundred diagnosed cases of inguinal hernia were studied selected through nonprobability purposive sampling according to inclusion and exclusion criteria. Patients were divided into two groups; Group I. mesh repair with antibiotic prophylaxis (n=50) and Group II. Mesh repair without antibiotic prophylaxis (n=50). Antibiotic prophylaxis was given 60 minutes before surgical procedure. Surgical procedure was conducted by a consultant general surgeon or senior registrar. The surgical site infection (SSI) was defined as wound infection that developed within thirty days of surgery. Data was analyzed on SPSS version 21.0. The continuous and categorical variables were analyzed by student`s t-test and chi-square test respectively. The significant p-value was taken at ≤ 0.05. The mean +/S.D of study population of both groups was noted as 39+/10.4 and 41.5+/11.0 years (p=0.09). All the subjects were male with age range of 20-60 years. The frequency of surgical site infection (SSI) in group I (antibiotic prophylaxis) was 6% (n=3) compared to group II (without antibiotic prophylaxis) was 22% (n=11) with highly significant p-value (p=0.001). Statistically significant differences were noted for the complications like; serous discharge, seroma, erythema and stitch abscess. The surgical site infection in mesh repair open inguinal hernia was higher in present study than internationally reported incidence. The antibiotic prophylaxis reduces morbidity in mesh repair open inguinal hernia. © 2014 Elixir All rights reserved