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The T-box transcription factor TBX3 is differentially expressed in non-small cell lung adenocarcinomas.

Non-small cell lung adenocarcinoma (NSCLC) is a leading cause of death in the United States and worldwide (1, 2). We mined published microarray data (3, 4, 5) to discover genes associated with NSCLC. We identified significant differential expression of the transcription factor TBX3 in tumors from patients with NSCLC. TBX3 may be of relevance to the initiation, progression or maintenance of non-small cell lung cancers.