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Development of a Decision Support System for the Treatment of Irradiated Persons – Modeling the Human Granulopoiesis

In this paper the modeling of the human granulopoiesis is investigated. We present an existing model of Fliedner and Steinbach and show how this biomathematical model is used to predict the severeness of the injury of an irradiated person. In order to improve the prediction a new model containing time delays is presented. The derivation of this model is carried out using partial differential equations. Furthermore the real time problems that occur during the prediction will be pointed out.