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Polyvinylpyrrolidone‐iodine as a disinfectant in eye surgery for five years

Abstract Polyvinylpyrrolidone‐iodine is a broad spectrum disinfectant which has been used in surgery for several years. The prophylactic effect of PVP‐iodine against panophthalmia was examined in a study including all cataract operated eyes (4111 eyes) from autumn 1981 to the end of 1986. The patients were randomly split up into two groups. Group 1 received PVP‐iodine eye‐drops as a pre‐operative disinfectant, the control group received 2.5% iodine on the skin only. Thirty‐two cases of panophthalmia arose, 0.8% in group 1 (21 out of 2550 eyes) treated with PVP‐iodine, and 0.7 % in the control group (11 out of 1561 eyes).