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Effects of fever on salivation response in the resting and exercising dog.

Abstract : The effects of pyrogens on the relationship between thermoregulatory salivation and hypothalamic temperature were studied in the resting and exercising dog at different environmental temperatures. The slope and threshold of the curve of salivation versus hypothalamic temperature were decreased in three afebrile dogs during exercise as compared to rest. With fever there was increase in the threshold for salivation both at rest and at 6.4 kilometers per hour at ambient temperature of 15C, 25C, and 35C. The slope of the salivation response curves at these ambient temperatures during fever was increased during rest and either unchanged or increased during exercise. (Modified author abstract)