{'fraction_non_alphanumeric': 0.03296703296703297, 'fraction_numerical': 0.034465534465534464, 'mean_word_length': 5.906896551724138, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
471 MOST INDIVIDUALS WITH TREATED BLOOD PRESSURES ABOVE TARGET RECEIVE ONLY ONE OR TWO ANTIHYPERTENSIVE DRUG CLASSES: CROSS-SECTIONAL STUDY OF AUSTRALIANS AT INCREASED CARDIOVASCULAR RISK

Objective: To measure, in a cohort of adults at increased cardiovascular risk and receiving antihypertensive therapies, the proportion with blood pressures above target (systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg) and to examine the association of blood pressure control with antihypertensive therapies, clinical and lifestyle factors. Design, Setting and Participants: A cross-sectional study of 3994 adults from Melbourne and Shepparton, Australia, enrolled in the SCReening Evaluation of the Evolution of New Heart Failure (SCREEN-HF) study; 3660 (92%) had private medical insurance. Inclusion criteria were age ≥60 years with one or more of self-reported ischaemic or other heart disease, atrial fibrillation, cerebrovascular disease, renal impairment, or treatment for hypertension or diabetes for ≥2 years. Exclusion criteria were known heart failure or cardiac abnormality on echocardiography or other imaging. The main outcome measures were the proportion of participants receiving antihypertensive therapy with blood pressures ≥140/90 mmHg and the association of blood pressure control with antihypertensive therapies, clinical and lifestyle factors. Results: Of 3623 participants (1975 men and 1648 women) receiving antihypertensive therapy, 1867 (52%) had blood pressures ≥140/90 mmHg. Of these 1867 participants with blood pressures ≥140/90 mmHg, 1483 (79%) were receiving only one or two antihypertensive drug classes. Blood pressures ≥140/90 mmHg were associated with increased age, male sex, waist circumference, and log amino-terminal-pro-B-type natriuretic peptide levels. Conclusions: Prescribing additional antihypertensive drug classes and lifestyle modification may improve blood pressure control in this population of individuals at increased cardiovascular risk.