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Effect of simvastatin on retinal vascular caliber: the Age‐Related Maculopathy Statin Study

created a small space in the corneal stroma, and the tissue staining dye replaced the preformed space. Femtosecond laser or microkeratome dissection has a flap-size limitation and needs additional mechanical dissection and extension procedures for large leukoma lesions. Further, lamellar flap procedure causes physical separation of the corneal stroma into two layers, which can hinder corneal mechanical reunion and weaken the adhesive bonding. Our technique differs from the conventional method because air infiltration is performed first in the corneal stroma and the preformed space is then replaced with the tattooing dye via a simple injection without repeated manipulation. The epithelialization could be achieved earlier than conventional stromal puncture method (Kim et al. 2011). Average period of epithelial healing was 9 days when calcium band removal was carried out for band keratopathy. When there was no calcium plaque on cornea, intact corneal epithelium could be observed on postoperative day 1 (Fig. 1). Tattooing after air bubble infiltration into the anterior stroma could prevent the invasive epithelial and stromal impairment resulting from the conventional stromal puncture technique and could bypass mechanical stromal cutting of cornea stroma from the conventional lamellar pocket method. Future histologic evaluations for dye toxicities would be necessary.