{'fraction_non_alphanumeric': 0.016018306636155607, 'fraction_numerical': 0.011441647597254004, 'mean_word_length': 5.782945736434108, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
A Systematic Review of Neurovascular Complications in Patients with Pseudoxanthoma Elasticum

Pseudoxanthoma elasticum (PXE) is a rare connective tissue disorder characterized by fragmentation and ectopic calcification of elastic fibers in the skin, ocular, and cardiovascular systems. The disease is linked to loss of function mutations in the ABCC6 genes and has a prevalence of 1 in 160,000 with a 2:1 female to male ratio.Although there exist sporadic reports of acquired PXE, the majority of cases are inherited in an autosomal recessive fashion. Characteristic cutaneous and ophthalmic manifestations of PXE include the presence of yellow papules in a linear or reticular pattern that often coalesce into larger plaques most commonly overlying flexural surfaces and angioid streaks in Bruch’s membrane, respectively. Additionally, gastrointestinal and retinal ABSTRACT