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Comparison of skin conductance with entropy during intubation, tetanic stimulation and emergence from general anaesthesia

Background:  The number of skin conductance fluctuations (NSCF) expresses sympathetic skin nerve activity. The response entropy (RE) measures electromyographic and electroencephalographic activity in the forehead. The state entropy (SE) measures mainly electroencephalographic activity. When the suppression of frontal muscular activity is complete, RE is equal to SE. RE‐Δ is defined as SE minus RE. The purposes of this study were to examine whether NSCF and RE‐Δ correlate with signs of clinical stress during intubation and tetanic noxious stimulation and to elucidate how rapidly and accurately entropy and NSCF react during emergence from general anaesthesia.