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Comprehensive Evaluation Method of Sensitization Model Based on Intuitionistic Fuzzy Cross-entropy

The current sensitization model evaluation method is either a subjective method to determine the sensitization by observing the state or degree of sensitization, or an objective method to measure the IgE concentration in animal serum. Since sensitization experiments are a complex and uncertain process, these methods are difficult to comprehensively reflect the degree of allergy. Here, this article proposes a comprehensive evaluation method for sensitization model based on intuitionistic fuzzy cross-entropy. First, use the intuitionistic fuzzy theory to establish the evaluation attributes for evaluating allergy experiments; then, combine the TOPSIS method with the intuitionistic fuzzy sets, and use the cross-entropy method to determine the weight of each evaluation attribute, and use the exponential distribution method to weight the selected continuous time series; establish a mathematical model for comprehensive evaluation of sensitization experiments. Finally, simulations verify that the method is reasonable and effective. The method proposed in the article can objectively and correctly evaluate the rationality of establishing sensitization model, and provide a more scientific and reasonable mathematical method for the evaluation of sensitization models and related biological models.