{'fraction_non_alphanumeric': 0.016332244517032198, 'fraction_numerical': 0.007932804479701353, 'mean_word_length': 5.617283950617284, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Liver Transplantation in Italy: Analysis of Risk Factors Associated with Graft Outcome

mate form of therapy for most patients with endstage liver diseases. It has become an established procedure with highly satisfying results because of the development of new preservation solutions, improvement in surgical techniques and perioperative management, and new immunosuppressive drugs. The number of liver allograft recipients increased in most countries until the 1990s; then, organ shortage has limited the number of transplantations, and waiting lists have increased considerably. The increasing demand for organs has expanded donor selection criteria and therefore has resulted in changes in donor characteristics. The critical shortage of organ donors is the reason for accepting lifesaving organs from so-called “marginal donors,” who would not have been considered suitable for transplantation previously. Although the outcome of liver transplantation does not seem to have been affected by the use of these donors, many investigators have identified factors that may have specific predictive values. Registry data are often a suitable basis for examination of outcomes. Although with limited details, a population-based registry can provide an accurate description of trends that represent the national situation. The source of our analysis is the Italian transplant registry, which was created on a voluntary basis in 1995 at the Italian Institute of Health, gathering information on donors, recipients, and organ transplantations performed throughout the country using a questionnaire similar to the one used by the Collaborative Transplant Study Registry in Heidelberg, Germany. The organ registry has been officially implemented after the establishment of the Transplant National Center, according to the last Italian law on transplantation. This retrospective follow-up study has been set up to provide the outcome of liver transplantations performed in Italy in the period 1995-2000, in terms of 5-year graft survival. We also analyze several donor and recipient variables associated with graft survival after liver transplantation.