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Sclerally directed processes of dopaminergic interplexiform cells reach the outer nuclear layer in rat and monkey retina

Abstract Tyrosine hydroxylase-immunolabeled wholemounts and sections of rat and monkey retina were observed at both the light- and electron-microscopic level. Small processes derived from sclerally directed processes of dopaminergic interplexiform cells were observed ascending to the outer nuclear layer where they were distributed between photoreceptor cells. A role in the regulation of disc shedding and/or melatonin biosynthesis is proposed for dopamine released at this level.