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Binucleate cells and liver karyometry.

Liver karyometry of uni- and binucleate cells was compared with karyometric measurements excluding binucleate cells in pervinous regions of rat liver parenchyma. Depending on their percentage of the cell population and due to their smaller nuclear size binucleate cells decrease nuclear volume means and the main maximum of frequency distributions of nuclear size (karyometric curves) but increase the lower second maximum in the range of smaller nuclear volumes. The main characteristics of the course of the curves, however, remain unchanged.