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[Effects of reduced dialysate calcium on mineral metabolism in hemodialysis patients].

AIM
To study the effects of decreased dialysis calcium on mineral metabolism.


METHODS
Dialysis calcium concentration was switched from 3.0 mEq/L to 2.5 mEq/L. Changes of serum Ca, P, and PTH were monitored for 6 months in 58 hemodialysis patients.


RESULTS
Serum calcium decreased 2 weeks after the switch of dialysate, although it returned to the basal level after 6 months because of increased dosage of vitamin D. Phosphorus transiently increased after the switch. I-PTH increased in patients whose i-PTH before the switch was less than 100 pg/mL. PTH decreased in patients whose i-PTH exceeded 300 pg/mL.


CONCLUSION
Decreased dialysis calcium produced lower serum calcium and better PTH control.