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Special Topics in Endocrinology and Metabolism

This is a special book that not only should be read by anyone concerned with sickle cell disease but will be read with pleasure by all those who appreciate a well produced medical monograph. The unique experience of the author and his team in Jamaica is here for all to share. He guides us through the literature, including the molecular pathology and the clinical and laboratory problems of management. He leaves us in no doubt of his personal opinions but at the same time refers us to other workers' reviews in copious references. Each chapter presents a review of a particular aspect from pathophysiology, diagnosis, and epidemiology to those on bones and joints, the gut, the lungs, and the renal system. The entire volume is lavishly illustrated with clinical photographs, laboratory material, x-rays, isotope scans, angiograms, and, indeed, anything that is needed to emphasise the author's point. The chapters on clinical management of the painful crisis, surgery, and the problems of pregnancy, give practical guidance based both on personal practice and published data. The comments on screening and sickle cell clinics are particularly timely with the current developments in genetic counselling. This is a reference work that is likely to be in common use rather than left to gather dust on the shelf.