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[An immunohistochemical study of vitreal and epiretinal membranes in human eyes].

Macrophages, monocytes and the expression of HLA-DR antigen in 52 cases of various vitreal and epiretinal membranes in human eyes were studied with the immunohistochemical technique. The results showed that more than 80% of the specimens were macrophage positive and expressed HLA-DR antigen, and monocytes were mainly seen in the specimens of proliferative diabetic retinopathy (41.7%). Macrophages were considered to play an important role in the development of epiretinal membranes, and immuno-response was also one of the related factors.