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A case of dominant dystrophic epidermolysis bullosa with diabetes mellitus presenting as progressive recalcitrant blisters and erosions

Dear Editors, Dominant dystrophic epidermolysis bullosa (DDEB) is a rare inherited blistering disorder resulting from mutations in the COL7A1 gene. This gene encodes type VII collagen, a major component of anchoring fibrils, at the dermal–epidermal junction. Its clinical features include recurrent blisters that primarily occur on the extremities as well as nail dystrophy. Here, we report a case of DDEB presenting as recent progressive recalcitrant blisters, which may be related to the onset of diabetes mellitus. A 71-year-old man was referred to our hospital with recent progressive recalcitrant blisters and erosions. The patient had been suffering from recurrent trauma-induced skin blisters and