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[The cutaneous symptoms of tuberous sclerosis].

Tuberous sklerosis is an autosomal dominant disease with a pleiotropic pattern of its clinical picture. The skin symptoms because of their early appearance are of great importance for the diagnosis of this disease, though not for evaluation of its progression and prognosis. Among the cutaneous lesions "white leaf-shaped macules" are the most frequent and earliest symptoms. Of similar importance is the "adenoma sebaceum", whereas the other skin signs are less relevant.