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Effect of the Xenograft Transplantation of Human Dental Pulp Stem Cells on Anxiety and Memory in Trimethyltin Induced-Alzheimer Disease Model

Received: 6 Feb, 2018 Accepted: 28 Jul, 2018 Abstract Background and Objectives: Alzheimer's disease (AD) is a neurodegenerative disease and the most common cause of dementia. The characteristics of this disease are amnesia, cognitive and verbal disorders, memory deficit, paranoia, depression, and anxiety. In this study, the alterations of cognitive-behavioral and nuclear factor kappa (NF-κ) factor, were investigated following the xenogenic transplantation of human dental pulp of stem cells on the AD animal model.