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[Primary results of rat experiments with long-term rotation in relation to the problem of artificial gravity].

Rats housed as a group per cage were centrifuged for 21 and 30 days at 1.1 and 2.0 G. The following parameters were measured: motor activity, body mass, static and dynamic endurance, acceleration (+Gz) tolerance, vestibular function, equilibrium function, skeletal muscle contractility, bone dynamics, gas exchange, blood biochemistry; weight of adrenals, thymus and thyroid gland; morphology of adrenals, thyroid gland, and cortex of the cerebellum nodulus; biochemistry of blood hormones, energy metabolism enzymes in the liver, bone phosphatases, myosin Ca-Mg-ATPase in the myocardium, protein sulfhydryl groups in the cerebellar motor cortex. The study has demonstrated that prolonged (1/50 of their life time) centrifugation of unrestrained rats causes no deterioration of many physiological functions, i.e., rotation produces no adverse effects on the animal body.