{'fraction_non_alphanumeric': 0.024505183788878417, 'fraction_numerical': 0.021677662582469368, 'mean_word_length': 5.247058823529412, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 1, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Development of molecularly imprinted biomimetic immunoassay method based on quantum dot marker for detection of phthalates

ABSTRACT In this study, a direct competitive molecularly imprinted biomimetic immunoassay method was developed for determination of the plasticizer dibutyl phthalate. Water-soluble carboxyl quantum dots were used as the marker. A hydrophilic molecularly imprinted polymer synthesized directly on the surface of a 96-well plate was used as biomimetic antibody. Under the optimal conditions, the limit of detection and the sensitivity of the method were 0.011 and 0.136 mg/L respectively. The cross-reaction values of two structural analogs were 4.75% and 6.89%, this indicaties that the method has the good specificity. Edible oil samples spiked with dibutyl phthalate were assayed, and good recoveries ranging from 80.0% to 111.5% were obtained. The method was used to detect dibutyl phthalate residues in liquors, and there were no significant differences obtained using the developed method and those obtained using gas chromatography.