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[Effect of phosphocreatine on the incidence of ventricular heart rhythm disorders in the 1st 24 hours of myocardial infarct].

Twenty-four-hour Holter ECG monitoring was conducted in 60 patients with acute myocardial infarction. Thirty patients received 2-hour intravenous creatine phosphate (CP) infusions at the rate of 4 g/hour, and the other 30 patients were taken as controls. The CP treatment was shown to reduce the incidence of ventricular arrhythmias within the first day of the attack. CP-treated patients showed significantly reduced incidence of paired extrasystoles, bigeminyes, early R-to-T extrasystoles and ventricular tachycardias, as compared to the controls.