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Natural and experimental nodular dermatomycosis in chickens.

The occurrence of unusual cases of generalised, tumour-like cutaneous swellings in 2-3-month-old chickens, from which A. flavus or C. albicans could be isolated, is described. Histologically similar but clinically different lesions could be produced experimentally in 1-month-old chickens by intradermal inoculation of A. flavus alone or combined with C. albicans. The latter organism alone failed, however, to produce the cutaneous lesions by the same route of inoculation. Intracardiac inoculation of A. flavus into chickens of the same age resulted in a systemic infection, including the nervous tissue, but without apparent involvement of the skin.