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Any place for antenatal diagnosis in the third trimester of pregnancy?

The need for a means of antenatal diagnosis of chromosomal abnormalities in the last trimester of pregnancy to avoid unnecessary intervention for the sake of the fetus is illustrated by a case in which polyhydramnios and suspected fetal hydrocephalus were found by ultrasound at 36 weeks gestation. The mother decided against early caesarian section for possible neurosurgery for the fetus. Later, she delivered vaginally of a baby with multiple abnormalities and trisomy 18.