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The diagnosis of osteoclastoma (giant-cell tumour): a radiological and pathological correlation.

Abstract The osteoclastoma (giant-cell tumour) is a rare lesion. Over half the tumours affect the ends of long bones especially around the knee, and in these cases radiological diagnosis is generally decisive. Atypical features have been seen in lesions of the upper end of the humerus and of the upper end of the femur. Radiological diagnosis is of limited value in osteoclastomata affecting the pelvis, spine, skull, ribs, clavicle, hands and feet. In such cases the importance of histology is obvious. On the other hand, some cases are illustrated where the histological diagnosis was difficult and radiology proved of great value. Osteoclastomata are extremely rare before epiphyseal closure. However, one example is illustrated of an undoubted osteoclastoma in the epiphysis of the greater tuberosity of the humerus in a boy of 13 years. Likewise, multiple osteoclastomata are rare. One example is presented of two osteoclastomata in the same patient.