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Opsonic Characteristics of Chylomicron-Bound Protein

Summary A blood protein in complex with native chylomicrons was labeled with radiogold colloid, thus indirectly identifying the protein material in the complex as op-sonin and suggesting the possibility that native chylomicrons may utilize the opsonin system for its clearance from the circulation. The protein in question has been shown to be at least divalent, in that the protein in com-binaton with one type of particle could still react with another. It is felt that these studies provide further insight into the complex surface events that result during the process of opsonization.