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An Experiment to Convert Structured Product Labels into Computable Prescribing Information

We report the methods, results, and some implications of an experiment to provide API access to reorganized, re-represented content from a current U.S. Food and Drug Administration (FDA) Structured Product Label (SPL). Using a question-and-answer pattern and current technical approach, we demonstrate that prescribing information in SPLs can be converted to a more granular, highly computable, API-accessible format. Our results suggest that computable prescribing information can be systematically published in drug product-specific modules, deployed and widely distributed via APIs, and integrated with downstream client apps to answer key questions about medications and compute patient-specific advice.