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Gastric and splenic infarctions in acute pancreatitis

Abstract Gastric infarction is a rare complication of acute pancreatitis. The proposed mechanism underlying this condition is a marked reduction of blood supply due to thrombotic occlusion of the vascular system. A review of the medical literature published thus far identified three reported cases of gastric infarction caused by acute pancreatitis. We report an additional case of gastric and splenic infarctions caused by acute pancreatitis in a 63-year-old woman. Laboratory investigation revealed increases of serum amylase, serum lipase, serum lactate dehydrogenase, blood urea nitrogen, blood creatinine, and blood C-reactive protein levels, as well as increases in the white blood cell count, indicating acute severe pancreatitis. Abdominal computed tomography revealed acute necrotic collection in the peripancreatic area, and gastric and splenic infarctions associated with multiple thromboses of the short gastric and splenic arteries. She received a total gastrectomy with a Roux-en-Y esophagojejunostomy and a splenectomy. At the follow-up examination, no symptoms were noted. This article is protected by copyright. All rights reserved.