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Early management of acute ischaemic stroke

This chapter, ‘Early management of acute ischaemic stroke’, addresses all the basic issues of thrombolysis as it has evolved over the last three decades. More importantly the journey and controversy concerning thrombolysis in older people is discussed at length with excellent trial evidence from specialist research. A review of all-important thrombolysis trials is succinctly described. New national clinical guidelines are analysed. Endovascular mechanical thrombectomy, which is rapidly developing, is described in detail with a review of the latest trials too. The author also highlights the importance of establishing cerebral blood flow as quickly and as completely and safely as possible.