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Prostate cancer grading: light and electron microscopy.

An attempt has been made to use various morphological patterns as predictors of the pathobiology of clinically active prostate cancer. At the present time, the most predictable and time-tested procedure is that of the Gleason grading and subsequent score results. Even though there may be some deficiencies, it is the best that is currently available to the surgical pathologist and urologist. All other morphological procedures can be additive to the Gleason grading system.