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EFFECT OF FEEDING OCHRATOXIN A AND CITRININ TOXINS ON CERTAIN BIOCHEMICAL PARAMETER IN BROILER CHICKEN

The present investigation deals with effect of ochratoxin A (OA), citrinin (CTN) and their combination on certain biochemical parameters in broiler chicken at weekly intervals. The broiler chickens were divided into four grou ps of 50 chicks each and fed with OA 1ppm, CTN 12.5 ppm and combination of OA+CTN (1 ppm OA + 12.5 ppm CTN) in feed up to 35 days of the experiment. The blood samples were collected from all the groups at weekly interval to study the effect of this toxin o n various biochemical parameters. Biochemically, hypoproteinemia, hypoalbuminemia, hypoglobulinemia and hypoglycaemia. The levels of blood urea nitrogen (BUN), serum creatinine, uric acid, AST, ALP, ALT and Serum triglyceride were increased significantly in all the toxin treated groups. However, biochemical alterations were maximum in the combination group than the individual toxin treated group. The interaction of both the toxins was found to be additive.