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[The clinical significance of renal functional reserve].

Patients at risk to develop intraglomerular hypertension were denoted among those with chronic glomerulonephritis (CGN) basing on the relationships between various clinico-laboratory findings, clinical syndromes and markers of intraglomerular hypertension (low or absent renal functional reserve). The risk groups include CGN patients with urinary syndrome and arterial hypertension with nephrotic disease and serum creatinine over 1.4 mg/%, with renal damage typical for focal-segmental glomerulosclerosis or fibroplastic glomerulonephritis. Patients with nonimmune progression via a rise of intraglomerular pressure should be given drugs reducing intraglomerular hypertension.