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One-Pot Synthesis of thiocarbamidoalkyl naphthols

An efficient, inexpensive and mild method for the synthesis of β-thiocarbamidoalkyl-β-naphthols, catalysed by p-toluenesulfonic acid at room temperature is reported. A set of thiocarbamidoalkyl naphthols have been synthesised in high yields from aromatic aldehydes, β-naphthol and N-phenylthiourea or thiourea. The procedure involves a short reaction time and a simple experimental procedure.