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Effect of Water Fraction in Selection of Optimal TI Value for STIR Sequences

Objective This article describes the effect of the water fraction in the selection of the optimal T1 value in a STIR sequence. This effect has been given little consideration in previous studies. Materials and Methods Therefore, using both STIR combined with the Dixon method (opposed-phase STIR) and conventional STIR (in-phase STIR), we have investigated the effect of the water fraction in the selection of an optimal TI value for the STIR sequence. Results Our findings have indicated that the water protons rather than the olefinic protons ( – CH = CH – ) play a major role in the opposed-phase effect in vivo. Conclusion Thus, it has been concluded that the most effective fat suppression can be achieved when the intravoxel phase cancellation effect between the water and lipid protons is maximal, rather than when the longitudinal magnetization of the lipid protons is minimal.