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Race/Ethnicity and Gender Differences in Hyperhomocysteinemia and Folate and Vitamin B12 Status in American Elderly

Abstract The purpose of this research was to study the racial and gender differences in the prevalence of hyperhomocysteinemia > 16.4 nmol/ml), and in the status of folate and vitamin B12 in the American elderly from the NHANES III data. Black males had the highest prevalence (17.3%) of hyperhomocysteinemia, followed by Mexican males (12.7%), White males (12.4%), Black females (10.6%), White females (9.8%) and Mexican females (3.4%). Higher incidences of hyperhomocysteinemia were associated with lower folate and vitamin B12 status. The Black elderly had the poorest folate status, followed by the Mexican and White elderly. Conversely, the White elderly had the poorest vitamin B status, followed by Blacks and Mexicans.