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A Study on Quality of Life Assessed by EQ-5D in Age-Related Macular Degeneration

Purpose : To evaluate the quality of life (QoL) in patients with age-related macular degeneration (AMD) with EuroQoL (EQ-5D). Methods : The number of subjects was 18,007 people over the age of 40 years who were undergone an eye examination using data on the 20082012 National Health and Nutrition Survey. AMD was classified into early and late stages using angiography. QoL was measured using five measurements (exercise ability, self-care, usual activities, pain/discomfort, anxiety/depression) using the EQ- 5D. Multiple logistic regression analysis was conducted to evaluate the association between AMD and QoL, and also adjusted for possible covariates. Results : The mean age of AMD patients was significantly higher than the control group (54.31±0.14 years) in the early(64.98±0.39 years)and late(65.97±1.35 years) stages. Even after adjusting for age, gender, residential area, education, occupation, smoking, drinking, exercise, BMI, diabetes and hypertension, anxiety/depression was increased in early AMD(odds ratio=1.42, 95% confidence interval=1.051.93). And even after adjusting for age, gender , education, occupation, smoking and hypertension, the risk of self-care was increased in late AMD(odds ratio=3.74, 95% confidence interval=1.0214.07). Conclusion : AMD was associated with QoL. This associated AMD may affect the wider range of patients' visual acuity as well as health and welfare. Therefore mental support with ophthalmic treatment would be considered importantly.