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[Placental changes in diabetes mellitus with special reference to villi maturation disorders. (Morphological findings and severity of the disease)].

The placentas of 42 cases with rhesus sensitization were examined. The degree of severity of this disease was classified according to the typing of Liley. There was found an increase of placental weight in relation to the degree of severity of rhesus sensitization. Similar relation was seen referred to the height of the placenta-child-index. Implantation lesions occurred in all degrees of sensitization. In the most cases we found insertion anomalies of the cord or shape abnormalities. All the placentas showed a disturbance of circulation, in 70% only in small areas. A relation to the degree of the severity of this disease wasn't provable. Nearly all placentas showed villi necrosis and proliferation of the syncytiotrophoblast. A compensatory angiomatosis was seen only 3 times. The authors found 85,7% distrubed maturation of the villi in rhesus sensitization; there was a relation between the degree of the changes and the degree of the severity of the disease. Dominant was the discordant retardation of the villi. These pathological findings have to be seen in correlation to the aetiology of this disease, causal treatment is not possible.