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A new focus on the methods of tissue engineering.

WE ARE PLEASED to introduce the first issue of the Journal Tissue Engineering Part C: Methods. Since its introduction at the beginning of the 1980s, the promise of tissue engineering has attracted a lot of attention from scientists, clinicians, patients, and investors. The expectation that many patients might benefit from relatively simple structural new tissue-replacing devices gave rise to ambitions as well as hope. As a consequence, research efforts have expanded rapidly during the last decennium, which has resulted in an enormous steep increase in the number of tissue-engineering publications (approximately 100 publications in 1993, 1250 in 2001, and 2700 in 2006). This increase also became visible for Tissue Engineering. Since its introduction, the number of issues, as well as the number of manuscripts per issue, has increased continuously. Fortunately, this increase was associated with a significant increase in the journal’s influence, making the journal an important element of this scientific field. The submissions are coming from around the globe, emphasizing the international coverage of the Journal, but we have also noticed that a clear distinction can be made in the type of submissions (original research papers, reviews, and methodology papers). In an effort to recognize the importance of methodology-directed research, in addition to hypothesisdriven research, a decision was made to launch a separate journal edition focused completely on methodology papers. This kind of publication is relevant to the continuous development of the field of tissue engineering. Many technological and scientific challenges exist in the development of tissue-engineered products and regulatory policies. These challenges require the emergence of new, sophisticated methods and techniques, further justifying the introduction of Tissue Engineering Part C: Methods. We would like to thank the staff of Mary Ann Liebert Publishers for their care and support of the production of this new edition. We will continue to advance the Journal and the publication of high-quality research, so we would like to encourage readers to submit their best research to Part C: Methods. We are also open to suggestions from researchers to ensure that the Journal provides an authoritative forum for presentation of the newest methodological developments in tissue engineering.