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Pulse reverse osmosis: a new theory in the maintenance of fluid balance

to this process. The presently accepted theory of fluid exchange was put forward by Starling’ in 1896. Apart from several suggested modifications2-6 the underlying mechanism has not been challenged until recently. Pulse reverse osmosis7 is a new theory of fluid exchange which addresses several of the problems inherent within the Starling hypothesis. Starling suggested that the capillary wall acts as an osmotic membrane separating the plasma and interstitial fluid. This membrane sets up an osmotic pressure gradient between these two solutions which tends to draw fluid into the