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Ventricular septal rupture after acute myocardial infarction: diagnosis by two-dimensional echocardiography.

A 69-year-old woman had ventricular septal rupture after acute anterolateral myocardial infarction. The defect was demonstrated directly by two-dimensional echocardiography. The appearance of negative contrast in the right ventricle during systole and microbubbles traversing the defect from right to left during diastole further confirmed the rupture. Two-dimensional echocardiography also accurately characterized the nature and extent of associated myocardial damage.