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Intravenous Corticosteroids: Adverse Reactions are More Variable than Expected in Children

High-dose intravenous corticosteroids (IVCS) have been used in the management of rheumatic diseases with increasing frequency. Corticosteroid side effects appear to be diminished. Case reports suggest only rare adverse reactions. This study assessed the frequency and severity of adverse effects of IVCS in a group of children with rheumatic diseases. Two hundred fourteen children received intra-