{'fraction_non_alphanumeric': 0.0225140712945591, 'fraction_numerical': 0.005628517823639775, 'mean_word_length': 5.935064935064935, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Pharmacodynamic and pharmacokinetic profile of SM‐1, a triple‐drug combination to increase total sleep time

The primary objective was to characterize the pharmacokinetics and pharmacodynamics of SM‐1 after administration of a single oral dose to healthy volunteers in a placebo‐controlled double‐blind trial of daytime sedation. Secondary objectives were to determine the onset, duration, and offset of the sedative effects using subjective and objective measures of sedation. Safety and tolerability of SM‐1 were also investigated.