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Critical considerations on a comparative study of two staging systems for multiple myeloma.

Material from a selected group of dead myeloma patients has been analyzed for the application of the staging systems proposed by Durie and Salmon and by Merlini, Waldenstrom and Jayakar. Neither of the systems showed prognostic significance in this myeloma population. No significant correlation was found between bone marrow plasmocytosis, renal function and survival. The selection of the myeloma population may be the major determinant in these discrepancies with data in current literature.