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Epidemiologic and field observations on avian influenza in Minnesota turkeys.

Avian influenza virus (AIV) was detected in Minnesota turkeys by virus isolation and by hemagglutination-inhibition (HI) tests with A/Turkey/Wisconsin/66 virus used as the HA antigen. The virus isolated appears closely related to the A/Turkey/Wisconsin/66 virus. The disease was seen primarily in turkey breeding flocks. The characteristic observed most commonly was a precipitous drop in egg production, sometimes to below 10% within 5 to 10 days. There was also a concurrent drop in fertility and hatchability. Many of the hens exhibited a depressed, listless attitude. Mild respiratory signs were noted in some outbreaks but not in others. All flocks remained serologically negative to HI tests for Newcastle disease and to complement-fixation tests for ornithosis. Several serum plate reactors to Mycoplasma gallisepticum (MG) were found early in the disease, but all flocks were considered negative on the basis of the HI test. All flocks were positive for Mycoplasma meleagridis by the serum plate agglutination test.