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Urinary hydroxyproline in psoriasis.

Urinary excretion of total hydroxyproline was determined in 153 cases of active psoriasis. Five of the patients had slightly increased and 37 had decreased values of hydroxyproline, but the patients with psoriasis as a group did not significantly differ from the controls. The results suggest that urinary hydroxyproline determination has no value in the diagnosis or clinical evaluation of the disease activity in psoriasis.