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Recurrent Pregnancy Loss, Causes, Controversies and Treatment

This book comprises 19 Chapters by many international and well-known authors, encompassing the epidemiology, genetics and possible causes of recurrent pregnancy loss and a final thought provoking chapter written from the patients’ perspective. The book opens with a comprehensive overview of the epidemiology of recurrent pregnancy loss and explores the possibility of the fetus signalling its presence to the mother, which may modulate the maternal immune system towards tolerance prior to implantation. The theoretical basis for the investigation of recurrent miscarriage is clearly stated and all the investigations usually recommended by most authorities are considered in depth. Two chapters in particular debate the value and advisability of fetal karyotyping and preimplantation genetic diagnosis. The reader is led easily to the rationale behind the common treatment regimens widely employed today. The common treatment modalities employed are widely covered and debated by several authorities without being prescriptive. Many of us involved in counselling patients who have suffered this common and distressing problem will find these debates particularly useful. This is not light reading but is a well-balanced treatise on this common problem and would provide a good source of reference for any early pregnancy assessment unit. It provokes much thought and offers many suggestions for future research. It provides a valuable educational resource and as such, it is recommended to those in the field and to all post-graduate libraries.