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Optical trapping and micromanipulation in microchannels with various configurations

Trapping and manipulation of microparticles using optical tweezers is usually performed within a sample cell formed by two parallel microscope cover slides. In this paper we discuss and demonstrate trapping and manipulation conditions when the cell has more complex configurations like microchannels or capillary tubes. The microchannels are fabricated on the surface of the cover slide by means of lithographic techniques. Experimental results of trapping and micromanipulation for silica microspheres and biological samples immersed in water show the usefulness of our study for microfluidics and biological applications.