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A compact and cost-efficient photoacoustic microscopy system with a pulsed laser diode excitation

Optical-resolution photoacoustic microscopy (OR-PAM) has demonstrated the capability of mapping microvasculature and is promising for biomedical applications. However, the popularity of the PAM system is limited due to the use of expansive and bulky laser sources. In this paper, a compact and cost-efficient OR-PAM system with a laser diode excitation has been developed. The black threads, phantom made of polyethylene tubes filled with rat blood, and a mouse ear were imaged to evaluate the PAM and demonstrate its capability of imaging biological tissue.