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S932 Active Tuberculosis and Opportunistic Infections: Pooled Safety Analysis of Ustekinumab Through up to 5 Years Across All Approved Indications

Fisher’s exact test was performed to compare each clinical outcome between age groups. Need for corticosteroids was defined by any oral corticosteroid prescription written for IBD symptoms during the follow-up period. Patients met the combined intestinal outcome by developing at least one internal fistula, intra-abdominal abscess or intestinal stricture during follow-up. Major adverse gastrointestinal event (MAGE) was defined as one or more of the following outcomes occurring during the follow-up period: need for corticosteroids, internal fistula, intra-abdominal abscess, intestinal stricture, peri-anal disease, IBD-related surgery, or IBD-related hospitalization.