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Investigation of the prevalence of obstructive sleep apnea syndrome in patients with diagnosed subclinical hypothyroidism

Aim: The aim of this study is to determine the prevalence of obstructive sleep apnea syndrome(OSAS) in two groups and to compare the demographic characteristics, the chronic diseases and the polysomnographic data in these two groups. Material and Method: 120 patients were included in the study. They were divided into two groups according to the diagnosis of subclinical hypothyroidism. The first group consisted of 60 patients with normal thyroid function. The other 60 patients who were newly diagnosed with subclinical hypothyroidism formed the second group. The demographic, the anthropometric and the polysomnographic data with the Epworth Sleepiness Scale(ESS) scores of the patients were recorded and compared. Results: The gender ratios, the mean ages, the distribution of chronic diseases, the body mass indices, the neck circumferences and the Epworth Sleepiness scale scores were found to be similar in both two groups. There was no significant difference between the groups in terms of OSAS prevalence and severity. A significant difference was found in the nocturnal desaturation and the oxygen desaturation index in the patients with subclinical hypothyroidism compared to the control group. Conclusion: The nocturnal desaturation is significantly increased in the OSAS patients with subclinical hypothyroidism. Our findings suggest that the diagnosis and the treatment of OSAS in the patients diagnosed with subclinical hypothyroidism might be a key to preventing the cardiovascular complications associated with nocturnal hypoxemia.