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Association of Kidney Stones with Metabolic Syndrome Parameters in Indonesia

Background: Kidney stone disease is common throughout the world with the lifetime risk of kidney stones in the United States exceeding 12% in men and 6% in women. In the United States, the prevalence of metabolic syndrome is 24% in men and 23.4% in women. Elevated prevalence of kidney stones is often associated with metabolic syndrome and metabolic syndrome itself. Objective: To assess the association between kidney stones and metabolic syndrome parameters in differences gender. Methode: Using a cross-sectional study, data obtained from secondary data of Riset Kesehatan Dasar (Riskesdas) 2013. A total of 26,063 people were as respondents in our study. Diagnosis of kidney stone based on Riskesdas 2013 interview. Metabolic syndrome was diagnosed according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) and PERKENI. Chi-square test and multivariate logistic regression were used in data analysis. Result: Number of respondents have been diagnosed with kidney stones by doctors was 226 (0.9%) respondents from 26,063 respondents. Central obesity was a dominant factor which associated with the risk of kidney stones in male respondents (OR 1.9; 95% CI 1.3-2.9; p=0.003) after adjustment for age. Metabolic syndrome was a dominant factor which associated with the risk of kidney stones in female respondent (OR 6.1; 95% CI 3.4-11.3; p<0.001) after adjustment for age. Conclusion: Metabolic syndrome and central obesity were associated with the risk of kidney stones.