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Neutrophil-lymphocyte and hematocrit scoring in acute pancreatitis as an early predictor of severity and outcome

Acute pancreatitis (AP) is an inflammatory condition of the pancreas causing local tissue and systemic complications. The presentation may vary widely from no symptoms to systemic inflammatory response syndrome (SIRS), persistent organ failure (POF), and death. The incidence of the disease is increasing throughout the world, especially in developed countries. The aetiology most commonly includes alcohol use and gallstones. Other causes of AP include invasive procedures such as endoscopic retrograde cholangiopancreatography, surgery, medications, infections, hyperlipidemia, hypercalcemia, biliary system anomalies, and idiopathic causes. The management of these patients will be determined from accurate assessment of severity of the disease. Multiple severity scoring systems have been designed to help clinicians in triaging AP patients and predicting their prognosis due to the diverse presentations of AP like The Ranson score, the acute physiologic assessment and chronic health evaluation II (APACHE II) score, the Bedside index for severity in AP (BISAP) ABSTRACT