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A comparative study of AJCC and the modified staging system in pT2/pT3 penile squamous cell carcinoma – a validation on an external data set

The recent changes in the American Joint Commission on Cancer, 8th edition (AJCC‐8E) pT2 and pT3 tumour definitions for penile cancer need robust validation studies. A recent study redefined and modified the pT2 and pT3 stages incorporating the histopathological variables (tumour grade, lymphovascular invasion, perineural invasion) similar to that used in the current AJCC‐8E pT1 stage tumour subclassification. In this study, we validate and compare this proposed staging with the AJCC staging systems on an external data set.