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The Inhibition of Virus Adsorption by Substances Induced by DEAE-Dextran and Poly I:C

Summary The adsorption of mengovirus to L-M cells is inhibited either directly by DEAE-dextran or by substances released into culture media from cells exposed to DEAE-dextran and DEAE-dextran combined with poly I:C. Therefore, preparations containing interferon induced in cell cultures in which DEAE-dextran is used to facilitate the uptake of poly I:C should be appropriately controlled to account for this activity.