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Effects of probucol on hepatic tumor necrosis factor‐α, interleukin‐6 and adiponectin receptor‐2 expression in diabetic rats

Background and Aims:  Probucol is a lipid‐lowering agent with anti‐oxidant effects. Oxidative stress and inflammation are important in the pathophysiology of insulin resistance. We aimed to evaluate the effects of probucol on liver histological changes, serum and hepatic levels of adipokines in rats with high fat‐induced type 2 diabetes (T2D).