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Implementation of an accelerated recovery program for pancreatoduodenectomy

Annotation. A number of issues concerning the practical application of the program of accelerated recovery of patients after surgery without compromising their safety remain debatable. The purpose of this study was to assess the feasibility of ERAS program for patients who undergo pancreatoduodenectomy (PD) and its impact on postoperative results. The study included 60 patients from 28 to 75 years old with benign and malignant pathologies of the pancreas and ampullary region, in which PD was performed between January 2015 and December 2018. The preoperative components of ERAS program were fulfilled in all patients. Mathematical data processing was performed using the software Statistica 64 ver. 10.0.1011.0 (StatSoft Inc.). All intraoperative components were implemented (100%) (except for epidural anesthesia – 85%). Postoperative components of ERAS program were implemented in the range from 56.7% to 100%. There was no postoperative mortality. Complications were observed in 16 (26.7%) patients in whom total number of complications was 22. The average duration of hospital stay after surgery was 13.1±4.1 days. The most of components of ERAS program for PD patients can be successfully implemented, decreasing the lengths of hospital stay without increase in number of postoperative complications.