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Infection of Human Fetal Membranes in vitro with Candida albicans: Die Infektion menschlicher Eihaute in vitro mit Candida albicans

Summary: The present study was designed to examine whether C. albicanscould infect and penetrate through intact human fetal membranes in vitro. Fragments of fresh fetal membranes were obtained from pregnant women undergoing a cesarean section. C. albicans was inoculated onto the surface of the maternal side of the membranes, after which the inoculated tissues were incubated at 31°C. C. albicanswas able to infect and penetrate through the membranes into the fetal side within 24 h of incubation.