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A modified oscillating sphere magnetic microrheometer for use with biological secretions.

An oscillating sphere magnetic microrheometer capable of measuring the viscoelastic properties of biological secretions of sample volume 5-100 mu l has been developed. Data acquisition is facilitated by linking the rheometer to a frequency response analyser. The instrument can be used over the frequency range 0.05 to 20 Hz, and reproducibility with purified mucus is better than +or-15%.