{'fraction_non_alphanumeric': 0.029333333333333333, 'fraction_numerical': 0.022, 'mean_word_length': 5.414529914529915, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 1, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
A RARE CASE OF ARIPIPRAZOLE INDUCED RABBIT SYNDROME

Prolonged exposure to Dopamine (D2) antagonist drugs, might occasionally lead to a condition which is characterized by involuntary rapid frequency (5Hz) vertical axis tremors of the perioral muscles, that mimics the twitching of a rabbit’s mouth and is therefore called the Rabbit Syndrome (RS). Although RS is considered a long term Extra Pyramidal Symptom (EPS) seen in Typical Antipsychotics, its occurrence in an Atypical Antipsychotic, especially in Aripiprazole, with a unique partial D2 agonistic action is rather peculiar. We discuss a case of Aripiprazole Induced RS to sensitize practitioners to be cautious while prescribing and titrating Aripirazole. An elderly female suffering from recurrent depressive disorder with psychotic symptoms, developed oral tremors, after initiation of treatment with Aripiprazole. RS was diagnosed after examination and ruling out other causes. RS subsided after treating with Trihexyphenidyl. Naranjo’s algorithm for Adverse drug reaction showed a score of 7, indicating a probable association.Although the risk of developing EPS/RS on Voruganti et al (2020): A rare case of Aripiprazole Dec, 2020 Vol. 23 Issue 23 Annals of Tropical Medicine & Public Health http://doi.org/10.36295/ASRO.2020.232352 treatment with Aripiprazole is very less, it is prudent to be cautious while co prescribing with other medications and rapidly titrating the doses of Aripiprazole, particularly in the elderly population.