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A Complication after Intralesional Methylprednisolone Acetate Application to Oral Mucosa: A Case Report

SUMMARY Objectives: The purpose of this case report is to evaluate an abscess formation due to intralesional methylprednisolone acetate application to a patient with erosive oral lichen planus. Case Report: A 47 years old male patient with a histopathological and clinical diagnosis of erosive oral lichen planus (2×3cm) was treated with intralesional methylprednisolone acetate injection (5 injections of 0.1cc each around the lesion every 15 days). An infection developed after the third application. Magnetic resonance imaging (MRI) revealed an abscess formation, and the patient was hospitalized for further treatment. Conclusion: Although systemic adverse effects are seldom seen in intralesional steroid application, mucosal atrophy is the main local side effect of this method. In this case, the cause of abscess formation could be an inoculation of the oral flora into submucosal tissues. Therefore, asepsis and oral disinfection are mandatory in intralesional applications.