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Progress in Neurology and Psychiatry Vol. 24

Acrodystrophic Neuropathy By JOHN D. SPILLANE and CHARLES C. WELLS. Pp vii 4109, illustrated. London: Oxford University Press, 1969. £2 10s. The central content of this monograph is a report of the clinical and radiological features in sixteen patients with peripheral sensory loss, trophic ulceration and osteolytic lesions in the extremities. In addition, there is an extensive historical review of previous interpretations of this syndrome. Semantics and nosology are discussed at some length, the authors advocating the term 'acrodystrophic neuropathy' to describe the clinical picture without implying any specific aetiology. It could perhaps be argued that a combination of biochemical, electrophysiological and morphological advances might allow a more precise classification of hereditary neuropathies in the future. The topic is a difficult one and any relevant new information is worth recording. The clinical photographs and X-rays will prove useful to those who have not seen many cases of 'acrodystrophic neuropathy'.