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Gyrate atrophy of the choroid: two cases.

INTRODUCTION
Gyrate atrophy of the choroid (GA) is a rare, inherited choroidal dystrophy that results in progressive deterioration in peripheral and night vision. This is the first documentation of GA in Singapore.


CLINICAL PICTURE
This report illustrates 2 cases of a sibling pair from a consanguineous union, presenting with the classical clinical features and biochemical abnormality of this condition.


TREATMENT AND OUTCOME
One patient was treated with pyridoxine replacement and a low protein diet. However, his condition failed to improve. The other patient was left untreated.


CONCLUSION
Treatment was ineffective for the first patient. As yet, there is no proven treatment of GA.