{'fraction_non_alphanumeric': 0.029978586723768737, 'fraction_numerical': 0.014989293361884369, 'mean_word_length': 5.233333333333333, 'pattern_counts': {'":': 0, '<': 1, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 1, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
A Monoclonalantibodythat Specificallyinhibitshuman Salivary A-amylase Materials and Methods Preparation of the Monoclonal Antibodies

Our monoclonal antibody 88E8 specifically binds to and inhibits human salivary a-amylase (EC 3.2.1.1) and cross reacts negligibly with the pancreatic isoenzyme, inhibiting it by <1%, as compared with about 90% for the salivary isoenzyme. The antibody binds the Si and S2 types of salivary a-amylase, but no pancreatic a-amylase isoenzyme forms. A pancreatic a-amylase assay involving 88E8 is under development, with a-glucosidase as auxiliary enzyme and pnitrophenyl-maltoheptaoside as substrate; we give preliminary data on this assay. The assay has to be done by substrate start, because the antibody interacts very slowly with the enzyme in the presence of substrate. Assay results for pancreatic a-amylase correlate well with those for isoamylase assayed with use of an inhibitor from wheat-germ.