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Double-blind evaluation of cimetidine as an adjunct to the routine double contrast upper-gastrointestinal examination.

Cimetidine, an effective gastric hydrogen receptor antagonist, is evaluated as a secretion eliminator in a routine double contrast upper-gastrointestinal study to improve areae gastricae visualization. One-hundred patients in a double-blind study used cimetidine or a placebo. Results suggest that acid secretion blockage with limited dosage has no advantage in micromucosal visualization.