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Immunity and Gilles de la Tourette syndrome: A systematic review and meta‐analysis of evidence for immune implications in Tourette syndrome

The neurobiology of Gilles de la Tourette syndrome (GTS) is known to involve corticostriatal loops possibly under genetic control. Less is known about possible environmental triggers of GTS. Specifically, immune‐related events following possible environmental inducers have been evoked, but important controversies still exist. In this systematic review and meta‐analysis, we looked for evidence in favor of such possibilities.