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Epidemiologic typing systems for coagulase-negative staphylococci.

An adverse consequence of advances in invasive therapeutic procedures and prosthetic surgical implants has been an increasing incidence of serious nosocomial infections with coagulase-negative staphylococci (CNS). Many of these infections are preventable; however, prevention requires an understanding of the important reservoirs and means of transmission. This has been hampered by lack of an adequate typing system for both prospective epidemiologic studies and outbreak investigations. Powerful techniques, some not previously used for typing CNS, might be useful in future efforts to better understand the hospital epidemiology of these important pathogens. However, further research is required to validate new typing systems.