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Electrochemical investigation of nano-electrodes for biomedical sensing applications in the brain

Using neural probing devices implanted in the brain, neural activity from neural cells can be recorded in-vivo for long term periods. This research goal is to develop and investigate a neural sensing device using nanotechnology which can enhance the quality and longevity of sensing. In this research, two neural electrode designs were employed with nanostructures, which distinguish them from 2-dimensional planar electrode configuration. According to electrochemical simulation, high molecular confinement has been observed on vertically aligned nanowire electrodes, especially those with grid structures. The efficacy of the 3-dimensional nanoelectrode is also discussed in this paper, depending on the molecular diffusion on nanoelectrodes.