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Anti-hypercholesterolemic effect of unripe Musa paradisiaca products on hypercholesterolemia-induced rats

Hypercholesterolemia has been implicated as a primary risk factor related with the pathogenesis of cardiovascular disease. This present study aimed at examining the effects of unripe plantain (Musa paradisiaca) products (elastic pastry and roasted plantain) commonly known as â€˜amalaâ€™ and â€˜boliâ€™ respectively in Nigeria on hypercholesterolemia-induced rats. This manuscript revealed that the inclusion of â€˜amalaâ€™ and â€˜boliâ€™ in hypercholesterolemic rat diets not only significantly decreased the high levels of plasma LPO, total cholesterol, triglyceride, low density lipoprotein cholesterol and plasma liver biomarkers, but also increased the activities of high density lipoprotein cholesterol in the plasma of treated animals as compared to the control. Finally, suggests that unripe plantain products â€˜amalaâ€™ and â€˜boliâ€™ confer protective effects against various biochemical changes in experimentally-induced hypercholesterolemic animal models.