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Breast Cancer Classification: A Review

Breast cancer becomes one of the most serious health issues among women and leading cause of death among them. Breast cancer continues to be prevalent and growing malignancy among women. While since last two decades, breast cancer research has led to a remarkable progress in understanding the breast malignancies and thus resulting in treatments of less toxicity and more efficiency. Breast cancer is a diverse disease having different molecular and histological features; and different groups of breast cancer response differently to different treatment therapies. Besides stage of the disease, the rate of prognosis and survival also depends on molecular subtype. So, for the proper treatment of breast cancer, it is important to know the complete classification of breast cancer and their response to different treatment strategies. About 25% of histological type of breast cancer is invasive breast cancer. Based on morphology, behavior and clinical presentation invasive breast cancer show broad range of tumor types. Molecular classification generally based on gene expression of mRNA. Molecular subtype provide new provides for the treatment strategies for breast cancer treatment.

Key words: breast cancer, classification, histological subtype, estrogen receptor, molecular subtype