{'fraction_non_alphanumeric': 0.02440677966101695, 'fraction_numerical': 0.006779661016949152, 'mean_word_length': 5.15, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
A new treatment option for treatment-emergent central apnea syndrome: a case series

Introduction: Most of the patients with treatment-emergent central apnea syndrome (TECSA) experience resolution of central apneas after 2-3 months of CPAP treatment. For patients who do not respond to CPAP therapy, BPAP-ST or ASV modes are recommended. The aim of this case series is to show the efficacy of APAP (automatic positive airway pressure) devices in the management of TECSA. Methods: In this case series, the clinical features and treatment results of 5 male patients who started using APAP (automatic positive airway pressure) devices for TECSA treatment in our clinic during 2019 were retrospectively analyzed. Results: The clinical characteristics and treatment results of the patients are summarized in Tables 1 and 2. Two patients used an APAP device with a forced oscillation technique (FOT) and the others used APAP devices that could differentiate central apneas using the obstructive pressure peak (OPP) method. In Patient 1, even in the second week of the treatment, total regression of the central events was evident, while longer-term treatment results were also successful in the other patients. Discussion and Conclusion: APAP devices are constantly updated. The new algorithms including FOT / OPP differentiate central apneas more effectively and prevent unnecessary increases in pressure. APAP devices with these new algorithms can be a treatment option in TECSA.