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Avastin in combination with Tarceva for patients with a specific type of advanced lung cancer

The pivotal phase II JO25567 study showed a statistically significant 46 percent relative reduction in the risk of disease progression or death (median PFS: 16.0 months versus 9.7 months; [HR]=0.54, p=0.0015) for people treated with the combination of Avastin plus Tarceva compared to Tarceva alone. Avastin and Tarceva each target pathways which are known to be key drivers in the development and growth of tumours, and the beneficial effect of Avastin plus Tarceva is supported by results of other clinical studies which showed the combination was effective and tolerable.