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Renal Tubular Necrosis and Liver Damage

A 40-year-old woman developed renal tubular necrosis and liver injury following ingestion of acetaminophen 1 g 12 days after halothane anesthesia. The possibility of a synergistic association between halothane and acetaminophen, and of probable hepatic and renal damage occurring after a low dose of acetaminophen, as well as the possibility of renal tubular necrosis induced by halothane are discussed.