{'fraction_non_alphanumeric': 0.040865384615384616, 'fraction_numerical': 0.009615384615384616, 'mean_word_length': 5.08029197080292, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Immunopathology of Chronic Progressive Hepatitis in Nude Mice Infected with Low‐Virulent Mouse Hepatitis Virus

Progressive hepatitis in athymic nude (nu/nu) mice due to a low‐virulent mouse hepatitis virus, MHV‐2 cc, was examined for involvement of immunocytes and serum antibodies. At 3 to 6 weeks postinoculation (p.i.) a considerable number of Mac 1‐ and asialo GM1‐positive cells were accumulated in the affected liver and spleen. There were also some Thy‐1‐positive cells. Later than 2 weeks p.i., serum IgG and IgM antibodies were detected in parallel with virus‐neutralizing activity, while the IgG levels were lower than those of infected euthymic (nu/ +) littermates. By transfer of the infected nu/nu mouse serum, the recipient euthymic mice acquired resistance to lethal challenge infection with a virulent virus, MHV‐2.