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Involvement of glycosaminoglycans in vesicular stomatitis virus G glycoprotein pseudotyped lentiviral vector‐mediated gene transfer into airway epithelial cells

The involvement of surface molecules in HIV‐1‐derived lentivirus (LV)‐mediated transduction of airway epithelial cells has not been studied so far. The present study aimed to evaluate the role of glycosaminoglycans (GAGs) in gene transfer mediated by a third generation vesicular stomatitis virus G glycoprotein (VSV‐G) pseudotyped LV vector in an in vitro model of polarized airway epithelial cells.