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Diagnosis of clear cell sarcoma by real‐time reverse transcriptase‐polymerase chain reaction analysis of paraffin embedded tissues

Clear cell sarcoma (CCS) is a rare tumor with a very poor prognosis that occurs predominantly in the distal extremities of young adults. Most patients bear the t(12;22) reciprocal translocation, which involves the EWS and ATF1 genes. The diagnosis of CCS usually is easy but may be challenging in unusual sites, and the detection of EWS‐ATF1 fusion transcripts is helpful to rule out a metastatic melanoma.