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Bioethics and Contaminated Vaccines

We described herein the potential health risks and some bioethics considerations derived from the antipolio vaccines contaminated with the oncogenic monkey DNA virus, named simian virus 40 (SV40). The SV40 contaminated antipolio vaccines were administered to the human populations world-wide during the years 1955–63. Recently, with the advent of the PCR techniques, many groups found SV40 footprints in human tumour specimens as well as in normal tissues. Although no firm conclusions have yet been established for human diseases and S V40 infections. The introduction of a monkey virus with oncogenic potential in the human population provoked great concern and criticisms.