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A Fluid Balance Problem in Diabetes

serum electrolytes may be artificially depressed. This phenomenon is now well appreciated by most who give parenteral fluid therapy. Osmols due to urea can be ignored in the calculations, inasmuch as these are distributed through both intracellular and extracellular body water. Glucose in contrast is confined to the extracellular space; if high, therefore, this can produce the same effects as an elevated concentration of electrolytes in the calculation of the distribution of water itself.