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KINETICS OF TISSUE PROLIFERATION IN COLORECTAL MUCOSA DURING POST‐NATAL GROWTH

The main developmental event in the colorectal mucosa during post‐natal growth is a dramatic increase in the number of crypts of Lieberkühn, resulting from a longitudinal fission of pre‐existing crypts. In the present study, the kinetic aspects of this process have been analysed, using extensive gland and cell counts involving the entire colon and rectum of 24 male BD IX rats distributed into four age groups.