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Explaining variation in the burden of child and adolescent tuberculosis

We read with interest the recent correspondence from Chen et al. [1] regarding the burden of notified tuberculosis (TB) among adolescents and young adults in Taiwan. The authors report that 10–24 year olds constituted only 5.2% of all newly diagnosed TB patients in Taiwan from 2005 to 2016, and that this percentage declined from around 6% in 2005 to around 4% in 2016. They contrast these figures with our estimate that young people constituted 17% of all people developing incident TB globally in 2012 [2]. There are several factors that explain this apparently large discrepancy. The burden of tuberculosis in children and young people depends greatly on the intensity of the TB epidemic, the demographics of the population, and the success of prevention efforts http://bit.ly/2ETFTik