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Biophysical studies on the structure and function of molecules from the vertebrate myelin sheath

The myelin sheath is a crucial structure for the proper functioning of the vertebrate nervous system. We employ diverse methods to study the structure, function, and dynamics of the molecules specifically present in myelin. Eventually, we hope to better understand the details of the tightly packed myelin structure and the etiology of myelin-related diseases. The paper will provide background into the molecular structure of myelin, and recent results from our laboratory, dealing with the structure and function of selected myelin proteins, will be highlighted.