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Gut feelings: A role for the intestinal microbiota in anorexia nervosa?

Anorexia nervosa (AN) continues to perplex, and new lenses with which to view the disorder are essential to advancing understanding and enhancing treatment. Although a fundamental first step in treatment, few clinical trials exist that explore how best to renourish individuals with AN, and treatment approaches typically are based on clinical opinion or guidelines.1 Moreover, gastrointestinal effects of refeeding are uncomfortable, distressing, and painful, resulting in low treatment acceptance and high dropout.