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Observation on curative effect of noninvasive positive pressure ventilation on chronic obstructive pulmonary disease complicated with Type II respiratory failure

Objective To investigate the curative effect of noninvasive positive pressure ventilation(NIPPV) on the treatment of chronic obstructive pulmonary disease(COPD) complicated with Type II respiratory failure. Methods Clinical data of 42 patients with COPD complicated with Type II respiratory failure were retrospectively analyzed. The patients were divided into Observation Group(24 cases) and Control Group(18 cases), and both groups underwent conventional treatment. Observation Group underwent a treatment with noninvasive positive pressure ventilation(NIPPV) for 72 h based on conventional treatment. The change of blood gas and improvement in pulmonary function in both groups before and after treatment was observed. Results The respiratory rate(RR), heart rate(HR), oxygen partial pressure(Pa O2), partial pressure of carbon dioxide(Pa CO2), p H value of arterial blood and forced expiratory volume in first second(FEV1) of both groups were signifi-cantly improved after treatment, and Observation Group had a more significant improvement, and the difference was statisti-cally significant(P0.05 or 0.01). Conclusion NIPPV is an effective treatment for patients with COPD complicated with Type II respiratory failure.