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COMPARISON OF OUTCOME IN VERY PRETERM AND VERY LOW BIRTHWEIGHT INFANTS AT THE AGE OF TWO AND FIVE YEARS

In the nationwide cohort (1338 liveborn infants <32 weeks and/or < 1500 g), infant mortality was 27.2 % (n=364). At the age of 5 years 944 children could be traced; of these, 911 were examined during a home visit. Preliminary results of 542 children show a major handicap in 24 children (4.4%); minor handicap was present in 25 children (4.6%). Comparison to the results of the follow-up study at 2 years in the same children (4.2% and 10.0% respectively) showed a similar major handicap rate and a lower minor handicap rate.However, shifting between the various subgroups (normal, minor and major) had occurred, a more favourable outcome was seen in 52 children and a less favourable in 23 children. Possible explanations of such shifts will he discussed.