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[Usefulness of the determination of serum lysozyme levels in dogs with tumors].

In a control group of fifty-three clinically healthy dogs of either sex and ranging in age from four to ten years, the serum lysozyme activity (SLA) showed a mean value of 1.2 mg/l with a range (+/- 2 SD) of 0.6-1.8 mg/l. SLA was measured in a turbidimetric assay using a microcentrifugal analyser. In dogs with a variety of neoplastic diseases, the histopathological diagnosis was compared with the SLA-level. In a large number of cases, the increased SLA-levels corresponded with malignancy in neoplastic disease. Measuring the SLA-level in dogs may be helpful in the diagnosis of malignancies. Proper clinical examination is essential in differentiating between some interfering diseases.