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Multiple Sclerosis with Onset at 35 Months of Age

The patient, born on February 18, 1980, was the second child of healthy and unrelated Italian parents; she had an older healthy brother. The family history was unremarkable. Pregnancy, birth and postpartum development were normal up to the age of 35 months, when, four days after the onset of a febrile episode, she developed hypomotility, truncal instability and an ataxic gait that resolved gradually over the course of 20 days. Noncontrast computed tomography (CT), CSF analysis, blood and CSF cultures yielded normal findings; a diagnosis of acute cerebellar ataxia