{'fraction_non_alphanumeric': 0.03117206982543641, 'fraction_numerical': 0.0199501246882793, 'mean_word_length': 5.322834645669292, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 1, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Changes of β-1,4-Galactosyltransferase with the Development of Endometrial Cancer

To elucidate the mechanism of the type 2 carbohydrate chain accompanying the development of endometrial cancer, we studied the expression of β-1,4-galactosyltransferase (β-1,4GT) in normal endometrial and endometrial cancer tissues. An immunohistochemical study revealed that β-1,4GT was diffusely positive in the cytoplasm of endometrial cancer cells, and that the level of its expression was increased compared with that in normal endometrium. Also, β-1,4GT mRNA corresponding to 4.7 kb was very low in normal endometrium, while an intense signal was detected in endometrial cancer. Our results suggest that the increase of β-1,4GT contributes to the expression of the type 2 carbohydrate chain in endometrial cancer.