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The relationship between Anti-Mullerian Hormone and ovarian response and fertility outcome in infertile women undergoing assisted reproductive techniques (ART)

Background and Aim: Anti-Mullerian Hormone (AMH) is an indicator of the number and quality of eggs produced during the menstrual cycle, which is related to the number of antral follicles, and the outcome of assisted reproductive techniques. The aim of this study was to evaluate the relationship between anti-mullerian hormone levels and ovarian response and pregnancy outcomes in infertile women undergoing assisted reproductive techniques (ART). Materials and Methods: This cross-sectional study was performed on 186 infertile women who underwent assisted reproductive techniques (ART) referred to Besat Hospital Infertility Center, from 2016 to 2020 . Demographic information, FSH level, AMH level, number of gonadotropin injections, number of antral follicles and number of fetuses were evaluated. Also, pregnancy outcomes including abortion, fetal death, fetal malformation and birth were determined and recorded in a questionnaire. Results: The mean of anti-mullerian hormone level was 3.9 (0.1 to 12 ng / ml) and the mean of FSH level was 6.1 (0.6 to 12.7 IUI / L). A considerable association was observed between anti-mullerian hormone level with the number of ovarian follicles, number of injected HMG, number of eggs, number of total embryos (P <0.05). There was no significant relationship between anti-mullerian hormone levels with abortion, fetal death, live birth and neonatal malformations (P >0.05). Conclusion: Determination of AMH levels can help for administration of gonadotropins, prediction of the antral follicle numbers, the number of eggs and the quantity of embryos obtained.