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PRIMARY ATYPICAL NEUROENDOCRINE TUMOR OF THE THYMUS: A CASE REPORT

as well as 62 subjects with no lung cancer at pulmonology clinic, Persahabatan Hospital, Jakarta between July 2016 and October 2017 was done. The data regarding ages, jobs, active smokers, passive smokers, history of cancer in their families, history of chronic lung diseases, and EGFR mutation in subjects with lung cancer were obtained. Descriptive statistics, chi square hypothesis test, and logistic regression were used for analysis. Results: A total of 108 subjects ranged in age from 19–90 years. All the subjects in the case group showed the histopathology of adenocarcinoma, and 67.4% of them showed EGFR mutations. Subjects in the control group were mostly diagnosed with pulmonary tuberculosis(43.5%). The result of bivariate analysis showed that there is a significant association between passive smoker(P = 0.038, OR = 2,613; 95% CI:1038–6575) and age (P = 0,002; OR = 5378; 95% CI: 1698–17,029) with lung cancer in women. From multivariate analysis, it was found that there was a significant association between passive smoker(P = 0.047, aOR = 2,639, 95% CI: 1012–6878) and age(P = 0,005; aOR = 5,417; 95% CI: 1,685–17,412) with the occurrence of lung cancer in women. Conclusion: We concluded that adenocarcinoma is the most common types of lung cancer in women and age above 40 years is the factor most associated with the occurrence of lung cancer in women at Persahabatan Hospital.