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[Angiotrophic lymphoma in the paranasal sinuses].

Angiotrophic lymphoma (neoplastic angioendotheliosis) is a peculiar disease which increases large extraordinary sized cells originating from B lymphocytes, in the small blood vessels and the capillary vessels of each viscera of the whole body, including brain. This disease, which was first reported by Pfleger and Tappeiner in 1959, has many clinical manifestations. CNS, skin, lung, kidney, and adrenal gland are often damaged by the disease. A case of this disease appearing in the paranasal sinus with successful remission following chemotherapy is reported. The patient was a 78-year-old woman with bilateral occulomotor nervous paralysis. Ethmosphenoidectomy was conducted under a working diagnosis of pansinusitis following CT. The surgical specimens were studied histopathologically and diagnosed as angiotrophic lymphoma. Six courses of chemotherapy (THP-COP) were applied. This disease is not necessarily rare, but the possibility of its being overlooked without enough diagnosis and treatment is very high. If we detect and treat it at an early stage, recovery of the disease can be expected, as in the case described above.