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Comparison and clinical efficacy of local anesthetic solution xylocaine with and without adrenaline [1:200000] in dental extraction

Objective: The objective is to analyze most popularized xylocaine and to compare the adequacy of analgesia achieved and the effects of xylocaine hydrochloride 2% without adrenaline and xylocaine hydrochloride 2% with adrenaline (1:200,000), used as local anesthetics in dentistry for extraction of tooth. Materials and Methods: Two hundred and fifty patients of varying age and sex, requiring at least extraction of two teeth, were picked from the outpatient department of oral and maxillofacial surgery. In each patient, two teeth were extracted under local anesthesia, one under xylocaine plain and other under xylocaine with adrenaline. Time of onset, depth, and duration of analgesia were recorded. Conclusion: Lidocaine with epinephrine (1:200,000) local anesthesia efficacy in dental extractions is more effective than lidocaine without adrenaline in extraction of tooth, and the onset, duration, and depth of analgesia of xylocaine hydrochloride with adrenaline were good as compared to plain xylocaine (xylocaine without adrenaline). Thus, lignocaine as a local anesthetic may be an effective drug in dental extractions with the higher safety margin.