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Developmental Variation in Amygdala Volumes Among Children With Posttraumatic Stress

This article examined associations between indices of maturation (age and Tanner stage) and amygdala volumes in 24 youth (aged 7–14) with posttraumatic stress disorder symptoms and a matched control group. Fifteen of the youth with exposure to trauma were also re-evaluated one year later. A positive association between maturation and right amygdala volumes was observed in the trauma group but not in controls. Associations with maturation remained when controlling for a number of possible covariates and over time. Developmentally younger youth (Tanner stage 1 and 2) showed increases and older (Tanner stage 3 and 4) decreases in right amygdala volumes.