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PP.20.07: AN ASSESSMENT OF PULSE WAVE VELOCITY BY ARTERIOGRAPH AND MOBIL-O-GRAPH IN BARBADIANS

Objective: To assess how comparable measures of central pulse wave velocity (aPWV) by Arteriograph and Mobil-o-graph are in Barbadian hypertensive patients and controls; a population where coronary disease is only recently emerging. Design and method: Men and women with clinically diagnosed hypertension only, hypertension and diabetes or those who are healthy (free from diagnosed illness), residing in Barbados were recruited. Vascular measures were taken supine (after 20 minutes rest) by Arteriograph and Mobil-o-graph, two readings each, in random order. Bland-Altman analysis was performed for analysis. Results: 41 participants, aged 54 ± 10.8 years, body mass index (BMI) 29 ± 6.7 kg/m2 (mean ± standard deviation, SD), 44% men. Systolic, diastolic and central blood pressure (SBP, DBP, SBPao), heart rate (HR), mean arterial pressure (MAP) and aPWV were measured by the two devices. Bland- Altman analysis was performed. The 95% limits of agreement (±1.96 x SD) for the parameters were; -2.7 to 5.07 m/s for aPWV, -39.0 to 40.4 mm Hg for SBP, -28.7 to 21.9 mm Hg for DBP, -36.7 to 22.1 mm Hg for MAP and -10.9 to 9.8 beats per min for HR. The differences between the two devices was significantly different from zero for aPWV (1.2 m/s) and MAP (-7.4 mm Hg) (P < 0.05). Plots of the difference between Arteriograph and Mobil-o-graph against their mean gave consistently lower readings for MAP with Arteriograph compared to Mobil-o- graph, and also showed the magnitude of the differences in aPWV increased generally with values above approximately 9m/s. Conclusions: Although differences between Arteriograph and Mobil-o-graph readings for SBP, DBP and HR vary, they are not different in the assessed Barbadian participants. However, the mean differences in aPWV and MAP were both variable and different in this population with emerging coronary disease.