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Dynamics of exchange parameters of hormonal indicators in patients with climacteric syndrome associated with diabetes type 2 under the influence of complex therapy with application of antihomotoxicological agents

The objective: was to compare the efficacy of complex methods of treating climacteric syndrome in patients with concomitant type 2 diabetes mellitus (DM) by analyzing hormonal parameters before and after complex therapy using antihomotoxicological drugs. Materials and methods. We examined 58 patients aged 45-55 years with a climacteric syndrome on the background of a 2-type diabetes mellitus. Women of the 1st group (n = 28) received only basic therapy according to the National Consensus for the management of patients in menopause with concomitant DM of type 2. Women of the 2nd group (n = 30) were treated with antihomotoxicological drugs against the background of basic therapy. Results. The proposed complexes positively influenced the hormonal state of patients, and also reduced the severity of climacteric syndrome and psychoemotional component. More effective was a complex that included antihomotoxicological agents, which is confirmed by the dynamics of hormonal parameters. Conclusion. From the clinical point of view, the obtained results give grounds to recommend these complexes for the correction of hormonal disorders in women with menopausal disorders on the background of type 2 diabetes mellitus. Key words: climacteric syndrome, diabetes type 2, base therapy, antihomotoxicological agents.