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JAMA Oncology Patient Page. Immune Checkpoint Inhibitors.

How Does the Immune System Work? During an immune response, the immune system turns on to attack potentially harmful agents. The immune system also has ways to turn off. This limits the immune response and prevents damage to healthy tissues. T lymphocytes, or T cells, are immune system cells that can kill cancer cells. A T cell has special locations on its surface called receptors. Other cells or molecules attach to these receptors and turn the T cell on (activation) or off.