Nadav Ahituv, PhD

Department of Bioengineering and Therapeutic Sciences
+1 415 476-1838
Research Description: 

The Ahituv lab is focused on understanding the role of regulatory sequences in human biology and disease. Through a combination of comparative genomic strategies, biochemical assays, regulatory element analysis, human patient samples, mouse and fish genetic engineering technologies, and massively parallel reporter assays they are working to elucidate mechanisms whereby genetic variation within these sequences lead to changes in human phenotypes.

Primary Thematic Area: 
Human Genetics
Secondary Thematic Area: 
Developmental & Stem Cell Biology
Research Summary: 
Gene regulation and human disease



Comparative genomic characterization of the multimammate mouse Mastomys coucha.

Molecular biology and evolution

Hardin A, Nevonen KA, Eckalbar WL, Carbone L, Ahituv N

Dysregulation of STAT3 signaling is associated with endplate-oriented herniations of the intervertebral disc in Adgrg6 mutant mice.

PLoS genetics

Liu Z, Easson GWD, Zhao J, Makki N, Ahituv N, Hilton MJ, Tang SY, Gray RS

MPRAnalyze: statistical framework for massively parallel reporter assays.

Genome biology

Ashuach T, Fischer DS, Kreimer A, Ahituv N, Theis FJ, Yosef N

A novel ZRS variant causes preaxial polydactyly type I by increased sonic hedgehog expression in the developing limb bud.


Xu C, Yang X, Zhou H, Li Y, Xing C, Zhou T, Zhong D, Lian C, Yan M, Chen T, Liao Z, Gao B, Su D, Wang T, Sharma S, Mohan C, Ahituv N, Malik S, Li QZ, Su P