Research Paper Volume 12, Issue 1 pp 965—977

Prediction of hepatocellular carcinoma prognosis based on expression of an immune-related gene set

Figure 5. Comparison with other prognostic signatures and clinical characteristics. We calculated continuous prediction scores based on five other disease prognostic signatures and compared the different datasets using a univariate Cox model. (A) Mean C-index of IPSHCC, age, stage, gender, tumor invasion, and 5 reported signatures. Among 10 survival predictors, IPSHCC had the highest mean C-index (0.709) compared to age (0.526), stage (0.673), invasion (0.571), and gender (0.542). (B) P value comparison of IPSHCC and 5 reported signatures. Red block indicates the model is significant (P ≤ 0.05) while black indicates lack of significance (P > 0.05). IPSHCC demonstrated the lowest p-value among survival predictors (p = 9.22 × 10-7) across datasets.