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High School

Lesson 2

Case Studies: Influenza and HIV

Following the previous lesson in which students learned how pathogens adapt to overcome the immune system, the focus herein is viral replication and specifically, how influenza and HIV adapt. Students investigate the process of viral infection and replication generally and specifically as it relates to the two viruses in the lesson. Students use these concepts and view a video describing the influenza pandemic of 1918 to explain why some kinds of influenza virus are more deadly than others.

Lesson Questions

  • What steps are involved in viral infection and replication?
  • Why are some kinds of influenza virus more deadly than others?
  • How do flu viruses and HIV overcome immune system defenses?

Lesson Files