Over the last few decades, the field of information systems has shown a steadily increasing interest in design-oriented research. This is manifested through the emergence of different ontological and epistemological positions among IS researchers. Some challenges arise from this development, such as (a) a need to understand design-oriented IS research in relation to design-oriented approaches in other disciplines, and (b) a need for design theory representation that targets and is useful to stakeholders in both research and practice. This paper proposes a conceptual framework for understanding designoriented research, and its implications for research with a focus on meeting the two challenges mentioned above.