MRI technique could help with ADHD diagnosis

Recent research suggests iron levels in the brain could identify attention deficit hyperactivity disorder (ADHD) in children and lead to more individualized interventions.

A study published in the journal Radiology has identified a magnetic reasonance imaging (MRI) technique to measure brain iron levels that could provide accurate, non-invasive diagnoses.

ADHD can be hard for doctors to distinguish from other psychiatric conditions, particularly because diagnosis is based on subjective clinical consultations.

Psychostimulants such as Ritalin are the most commonly proposed solution, further complicating the controversy that surrounds misdiagnosis, since many are opposed to such drugs for young people due to potential for abuse and lack of time-tested certainty of their effectiveness.


Researchers worked with 22 children and adolescents diagnosed with ADHD, 12 of whom had never been given medication, and measured their brain iron levels using a magnetic resonance imaging (MRI) technique known in the medical community as "magnetic field correlation imaging."

They compared results with those of 27 healthy children and adolescents and found that the 12 ADHD patients never exposed to psychostimulants had lower levels of iron in the brain compared with both the healthy group and the medicated ADHD patients.

The result not only suggests psychostimulants might restore deficient brain iron levels but could lead parents opposed to the use of the drugs to a better understanding.


Magnetic field correlation imaging was introduced in 2006 by study co-authors and faculty members Joseph A. Helpern, Ph.D., and Jens H. Jensen, Ph.D.


If the magnetic field correlation technique proves to be effective, more research could lead to pinpointing which patients are candidates for psychostimulants in the interest of minimizing their use amongst the young.
