Research Paper Volume 12, Issue 24 pp 25643—25657

Neurofilament degradation is involved in laparotomy-induced cognitive dysfunction in aged rats

Figure 4. Laparotomy alters hippocampal protein profile in rats. (A) List of regulated proteins in hippocampus of aged rats at 6 h after surgery. (B) Hierarchical clustering of differentially regulated hippocampal proteins exhibiting their expressions in surgery group vs. control, surgery + TSA and TSA groups. Up-regulated protein expression values are displayed in red, the down-regulation values are in blue, and the intermediate values are in shades of red and blue.