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Serum uric acid: Marker for atherosclerosis as it is positively associated with “atherogenic index of plasma”

Context: Serum uric acid (SUA) has been known to be associated with cardiovascular diseases. “Atherogenic index of plasma” (AIP) is considered a very sensitive predictor of future cardiovascular events. Objectives: This study was conducted to analyse the association of AIP with SUA and various other lipid parameters. Methods: Parameters were measured on a fully automated analyser using standard reagent kits in a retrospective study involving 248 male Indian subjects between 40 to 59 years of age. Results: AIP correlates: moderately with TC/HDL-C (r = 0.47, p < 0.0001); to a lesser extent but comparably (r = 0.2, p < 0.01) with SUA, LDL-C/HDL-C and TC; negligibly with LDL-C and age. Discussion and conclusion: As SUA is positively associated with AIP it can be used as a supplementary marker for atherosclerosis/CVD in upper-middle-aged men.