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Germicidal effect of pure electrolytic copper on the gonococcus.


 Asymptomatic gonorrhea is now considered to be the main cause of the high current incidence of gonorrhea, especially among women. Both in vivo and in vitro studies were carried out to assess the germicidal effect of copper on gonococcus strains. Of cultures taken from 32 men who exhibited suspicious symptomatology of gonorrhea and 27 women known to have had intercourse with them, 32 of the male and 20 of the female cultures were positive. 28 of the male and 16 of the female cultures exhibited a sensitivity to copper, i.e., the development of the gonococcus cultures was restrained by the introduction of copper to the culture medium. Of the 27 gonorrhea-exposed women who were tested, 2 had multiple locations of the disease and 20 had infections which were localized in the cervical mucus. For the last 20, culture and sensitivity tests of the gonococcus strains showed 14 to be sensitive to copper. These 14 women were fitted with a copper IUD in the endometrium; no other treatment was followed. The results were promising, giving completely negative culture results in every case where the disease had been localized in the cervical mucus. Therefore, although the bactericidal activity of copper and its salts is known to be of low degree, copper and its ions do seem to suppress or limit the spread of gonorrhea. Only large amounts would be effective in actually killing the gonococci in relatively short time periods.
