{'fraction_non_alphanumeric': 0.022658610271903322, 'fraction_numerical': 0.010574018126888218, 'mean_word_length': 5.436893203883495, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Failure of dopexamine to protect the hypoxemic newborn rabbit kidney.

The renal effects of dopexamine, a new dopaminergic agonist devoid of any alpha-adrenergic effect, were studied in 11 anesthetized newborn rabbits undergoing an acute hypoxemic normocapnic stress. Acute hypoxemia (PaO2 = 41 mm Hg) was associated with a marked increase in renal vascular resistance and a consequent decrease in glomerular filtration rate and renal blood flow. These changes were not modified by the administration of dopexamine at 10 micrograms/kg/min. Failure of dopexamine to blunt the hypoxemia-induced vaso-constriction suggests vascular dopaminergic receptor immaturity.