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Are PREDIST criteria better than PERCIST criteria as a PET predictor of preoperative treatment response in rectal cancer?

Fluorine-18-fluorodeoxyglucose PET/CT is an accurate tool for predicting the response to preoperative chemoradiotherapy in locally advanced rectal cancer patients. The need for standardization has contributed to the development of various criteria for harmonizing PET response. The novel proposed set of criteria called PET Residual Disease in Solid Tumor (PREDIST) seems to better distinguish between responder and nonresponder patients to chemoradiotherapy compared with the PET Response Criteria in Solid Tumors criteria.