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Ionogel based material for the colorimetric detection of Δ9-tetrahydrocannabinol

Cannabis sativa is the most widely abused illegal drug in the world. On the other hand, there is an increasing interest in the production of non-psychoactive industrial hemp for several applications, including the production of cannabidiol (CBD). This makes the easy and fast in situ detection of Δ9-tetrahydrocannabinol (THC), the illicit, psychoactive molecule that characterises drug-type cannabis a pressing need. It is here where detection mechanisms based on novel methodologies, e.g. microfluidics devices and new materials, offer interesting approaches that reduce reagents consumption and that minimise the generation of waste during the process. Moreover, fast analysis times and portability are of great importance to generate useful devices. Portability can be improved by using solid matrixes, where the detection mechanism could take place, such as an ionogel. In this work, we report for the first time the use of an ionogel matrix for the colorimetric detection of THC through the Fast Blue B Salt method. The integration of the Fast Blue B Salt into the ionogel matrix was studied as a first step in the development of a fully integrated sensor, for the identification of THC from hemp biomass and extracts.