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Juxtaglomerular cells tumor of the kidney: a case report with electron microscopic and flow cytometric investigation.

A juxtaglomerular cell tumor (JGCT) was found in the right kidney of a 17-year-old female who had suffered from a headache of 1-year duration and hypertension. CT and US were diagnostic in association with determination of plasma renin activity. Light and electron microscopic, immunohistochemical, and flow cytometric investigation of the resected tumor confirmed the diagnosis of JGCT with demonstration of ultrastructural features and distribution pattern of characteristic secretion granules of various sizes and shapes, coexistence of mast cells within the tumor (JGCT cells/mast cells = 10), and perivascular architecture.