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HUMORAL IMMUNITY IN PATIENTS WITH TINEA VERSICOLOR

Thirty patients with tinea versicolor (TV) and 30 age/sex‐matched healthy individuals were used to evaluate the anti‐Pityrosporum orbiculare antibodies (anti‐PO) using indirect immunofluorescence. Both serum IgG and IgM type anti‐P. orbiculare existed in both patients and controls. The antibody titers were significantly higher in patients, especially in those with erythematous lesions. Further analysis was performed and discussed in 120 controls at various ages. This investigation supports again that P. orbiculare, either as a pathogen or as a saprophyte, has enough antigenicity to produce specific humoral response in humans. The anti‐P. orbiculare antibodies may perhaps help explain the nonexistence of dermal invasion of this organism in the immunity‐intact host.