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Clonal Spread of IMP-1-Producing Pseudomonas aeruginosa in Two Hospitals in Singapore

ABSTRACT Thirty-six isolates of carbapenem-resistant Pseudomonas aeruginosa were studied. Pulsed-field gel electrophoresis revealed the presence of two clones. One clone carried a blaIMP-1 gene identical to that first described in Japan. The other clone carried a blaIMP-1 variant containing four silent mutations. One isolate with a unique pulsed-field gel electrophoresis pattern contained blaIMP-7.