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Chlorogenic Acid Enriched in Coffee Pulp Extract Attenuates Hepatic Steatosis by Modulating Gene‐regulated Lipid Metabolism and Lipid Transporters

Coffee pulp (CP) is the first by‐product of coffee processing. Major constituents in CP include chlorogenic acid (CGA), epicatechin (EC), caffeine exhibited antioxidant, lipid lowering action, and several biological activities. However, it remains unknown whether CP rich CGA improved hepatic steatosis. This study aimed to investigate the effect of CP aqueous extract (CPE) on hepatic steatosis, and identified the mechanisms involved in hepatocellular carcinoma (HepG2) cells.