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Effect of diabetes mellitus on operative outcome following laparoscopic cholecystectomy: A one year cross sectional study at tertiary care hospital

Background: Diabetes is reported to be a risk factor for gallstone formation. Diabetic patients are more prone to operative and post-operative morbidities. This study was aimed to find intra-operative difficulties and complications during laparoscopic cholecystectomy in diabetic and non-diabetic patients Patients and Method: This is a one year cross-sectional study carried out in a tertiary health center. Operative difficulties and complications studied in a total of 60 patients (30 diabetics + 30 non-diabetics) undergoing elective laparoscopic cholecystectomy from January 2014 to December 2014. Statistical analysis consisted of Chi-square test or Fisher's exact test, “p” value of less than or equal to 0.05 at 95% confidence interval considered as statistically significant. Results: Pre-operative characteristics including clinical presentation, duration of symptoms and vitals were comparable in diabetic and non-diabetics patients (p > 0.050). Significantly higher number of patients in diabetic group underwent open pneumoperitoneum (40% versus 16.67%; P = 0.045). Statistically significant difference noted in appearance of gall bladder, adhesions, dissection of Calot's triangle, releasing adhesions, intra operative bleeding, grasping of gallbladder, removal of gallbladder from liver bed, extraction of specimen, drain placement, and conversion (p < 0.050). The operative time was significantly higher in patients with diabetes mellitus (p < 0.050). Conclusion: Diabetes mellitus is significantly associated with operative difficulties and prolonged surgical time during laparoscopic cholecystectomy.