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Lymph node FNA cytology: Diagnostic performance and clinical implications of proposed diagnostic categories

Despite widespread clinical use, lymph node fine‐needle aspiration cytology (LN‐FNAC) lacks universal acceptance for definitively diagnosing lymphomas. This is likely due to reports of lower diagnostic performance, inconsistent terminology use in cytopathology diagnostic reports, and only limited data on the clinical implications of LN‐FNAC diagnoses. Recently, a uniform LN‐FNAC cytopathological diagnostic reporting system was proposed (the Sydney System). This study evaluated LN‐FNAC diagnostic performance and risks of malignancy associated with the proposed diagnostic categories.