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Clostridium difficile infection following outpatient cancer surgery

Althoughmost Clostridium difficile infections (CDI) are healthcareassociated, <25% occur during hospitalization.1 Increasingly, onset occurs in the community among patients who recently received medical treatment in inpatient or outpatient settings.2 The changing epidemiology of C. difficile from a hospitalto a community-onset infection coincides with, and may be driven by, trends toward shorter inpatient stays and more options for outpatient medical and surgical care.3 Patients undergoing outpatient surgery may be at risk for postoperative CDI due to preoperative healthcare exposures, preand postoperative antibiotics, or contact with contaminated fomites or colonized patients in the perioperative environment.4 The purpose of this study was to determine the incidence of CDI following outpatient cancer surgery, to describe characteristics of patients who developed postoperative CDI, and to identify possible C. difficile transmission events in an outpatient cancer surgery center.