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Rigor Force Responses Of Permeabilized Fibres From Fast And Slow Skeletal Muscles Of Aged Rats

1. Ageing is generally associated with a decline in skeletal muscle mass and strength and a slowing of muscle contraction, factors that impact upon the quality of life for the elderly. The mechanisms underlying this age‐related muscle weakness have not been fully resolved. The purpose of the present study was to determine whether the decrease in muscle force as a consequence of age could be attributed partly to a decrease in the number of cross‐bridges participating during contraction.