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Outcomes 
of long-term observation period in patients with myocardial infarction undergone radiopaque interventions in the acute period of the 
disease.

Introduction. Currently, the importance of various factors in the acute period of myocardial infarction (MI) for the risk stratification of unfavourable course ofpost-infarction period is continued to be studied. Purpose. We aimed to identify the factors, affecting the formation of adverse outcomes of in-hospital and long-term postinfarction period in patients with ST-elevated MI (STEMI) undergone radiopaque interventions (ROI). Material and methods. The study included 954 STEMI patients admitted to the Kemerovo Cardiology Dispensary in the period from 2008 to 2010. Diagnostic coronary angiography was performed in 725 (76%) patients, and 557 (76.8%) of cases undergone myocardial revascularization (isolated balloon angioplasty, angioplasty with stenting). Results. The in-hospital mortality in STEMI patients was associated with the age older than 60 years (OR 2.4 95% CI 1.4-3.9, p<0.001), decrease in left ventricular ejection fraction (LVEF) less than 40% on admission (OR 1.9 95% CI 1.1-2.9) and contrast-induced nephropathy (CIN) (OR 1.9 95% CI 1.0-3.5). The area under the ROC-curve was 0.744 (0.693-0.796; р<0.001). Fatal outcomes within a year after MI were associated with the decrease of glomerular filtration rate (GFR) less than 60 ml/min/1.73 m (OR 1.4 95% CI 1.0-2.0), LVEF less than 40% (OR 1.7 95% CI 1.1-2.7), development of CIN (OR 2.3 95% CI 1.3-4.1). The area under the ROC-curve was 0.707 (0.665-0.749, р<0.001). The risk offatal outcome within a three-year observation period was shown to increase 6.8-fold in the presence of acute heart failure (AHF) Killip > II on admission (OR 6.8 95% CI 2.1-21.8), 3.4-fold (OR 3.4 95% CI 1.1-11.0) in patients of the older age category (>60 years), 4.1-fold in development of CIN (OR 4.1 95% CI 1.1-14.3). The area under the ROC-curve was 0.744 (0.632-0.856, р=0.001). Conclusion. The independent risk factors of fatal outcome development within the in-hospital period in STEMI patients undergone ROI were: the age older than 60years, LVEF reduce less than 40% and the presence of CIN. Fatal outcomes within a year after MI were associated with GFR decrease less than 60 ml/min/1.73 m, LVEF less than 40% and CIN development, and within three years - AHF Killip class II and greater, age older than 60 years, as well as CIN after ROI.