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A monoclonal anti‐idiotypic antibody against anti‐receptor antibodies from myasthenic sera

A monoclonal anti‐idiotypic antibody has been developed against anti‐acetylcholine receptor antibodies purified from the serum of one myasthenic patient. The idiotype is present on a subpopulation of antibodies directed against the toxin‐binding region of the receptor. The monoclonal antibody cross‐reacts with antibodies from other myasthenic sera, suggesting shared idiotypic specificities.