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Occupational exposure to polyvinyl chloride as a risk factor for testicular cancer evaluated in a case‐control study

Occupational exposures were assessed in a case‐control study on testicular cancer using self‐administered questionnaires. In total, answers were obtained for 148 (91%) cases and 315 (87%) controls. Of the cases, 101 had seminoma and 47 had embryonal testicular cancer. An increased odds ratio (OR) was found for exposure to polyvinyl chloride (PVC) yielding an OR of 6.6 (95% confidence interval, 1.4–32). The risk increased further if cases with self‐reported cryptorchidism or orchitis were excluded. Six of the 7 exposed cases had seminoma. Exposure to other types of plastics did not significantly increase the risk of testicular cancer. Int. J. Cancer 73:828–830, 1997. © 1997 Wiley‐Liss, Inc.