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The annual cost of blood transfusions in the UK

Summary.  This study estimated the annual UK cost of blood transfusions in 2000/2001, updating a study we performed in 1994/1995. The analysis was based on published data, information from interviews with National Health Service (NHS) personnel and a structured questionnaire for blood donors. The annual cost of provision and transfusion of blood products increased by 256% in real terms, to £898 million in 2000/2001, whereas the number of whole‐blood donations increased by 2% to 2·8 million. The number of apheresis donations decreased by 52% to 70 000. Total blood product units issued to hospitals in 2000/2001 increased by 17% and were used in an estimated 1·7 million transfusions. The estimated NHS cost for an adult transfusion was £635 for red blood cells, £378 for fresh frozen plasma, £347 for platelets and £834 for cryoprecipitate. Blood donors incurred an annual direct cost of £8·1 million and 3·1  million hours of used leisure time. There was also an indirect cost of £7·2 million arising from lost productivity. The large increases since 1994/1995 reflect a real increase in expenditure by the blood transfusion services, partly due to the introduction of leucodepletion, greater hospital resource use due to more transfusions being undertaken and under‐recording of hospital activity in 1994/1995.