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Premenopausal osteoporosis, an overlooked consequence of anorexia nervosa

Many young women with anorexia nervosa develop premenopausal osteoporosis. In particular, female athletes have a much higher incidence of disordered eating than their peers and therefore are at a much higher risk of stress fractures and other traumatic bone pathology. This review summarizes factors affecting the development of premenopausal osteoporosis in these patients and identifies potential targets for intervention. Particularly at risk are female athletes. The etiology is complex; the key treatment is to restore body weight.