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Commentary: Alcohol Plus Chlorhexidine is More Efficient Than Alcohol Alone for Phenol‐Based Chemical Matricectomy: In Vitro Study

The technique of phenol cauterization is wellestablished in the medical literature and is usually presented with little variation. In the majority of the existing published protocols, the dilution of phenol with alcohol is described as an important step, but there are differing opinions with respect to its necessity and the agents required to perform this step. To this end, the work of Becerro de Bengoa Vellejo and colleagues makes an important contribution, using human skin and a diffusion cell apparatus to measure the amount of phenol recovered after lavage with specific substances. Although this study was performed in vitro, it is important in that it demonstrates the ability to measure, test, and verify the actions of diverse substances and their effects on phenol. Through the use of this apparatus, Becerro de Bengoa Vellejo and colleagues demonstrate that alcohol in conjunction with chlorhexidine is more efficient than alcohol alone for phenol-based chemical matricectomy.