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ADULT ACUTE LYMPHOBLASTIC LEUKAEMIA: A FIVE‐YEAR EXPERIENCE

The case histories of all patients for whom the diagnosis of acute lymphoblastic leukaemia (ALL) was made over a five‐year period at the Royal Adelaide Hospital and Institute of Medical and Veterinary Science were studied. There were 34 patients with a median age of 47.5 years. Adequate follow‐up was obtained on 33 patients, and their median survival was 5.4 months. The remission rate was 77% in the under‐30 years age group, but only 15% in the over‐30 years age group. The median duration of remission was 24 months while the median survival of remitters has not yet been reached. The median survival of non‐remitters was two months with 100% being dead at 12.3 months. Of 20 patients without remission, seven died of haemorrhage and/or infection before an adequate trial of therapy had been completed, while nine patients had “adequate” intensive therapy but failed to achieve remission.