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Serum immunoglobin E concentrations of allergic patients and blood donors. Influence of allergy, sex and race on IgE values.

Serum IgE concentrations were measured in allergic subjects attending the Allergy Clinic at Groote Schuur Hospital, Cape Town. White and Cape Coloured clinic subjects had serum IgE concentrations which were significantly higher than those found in comparable groups of either non-allergic blood donors or blood donors with symptoms of allergy; in Blacks these differences were not apparent. Although serum IgE concentrations in clinic subjects tended to increase in the order White -- Cape Coloureds -- Blacks, these racial differences were not as pronounced as in blood donors. Also, olinic subjects showed no sex difference in serum IgE concentrations.