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CHOICE OF TISSUE TO ESTABLISH THE DIAGNOSIS OF MAGNESIUM DEFICIENCY IN AN ANIMAL MODEL FOR THE HUMAN INFANT

To find the best tissue to assess the magnesium (Mg) status of the sudden infant death victim, male 28-38 g Sprague Dawley rats were fed fed diets containing 100 or 0 mg of Mg/ 100 g and 20 % casein (100-20 or 0-20) for 1 week; others were fed 150 or 5 mg of Mg/ 100 g and 40 % casein for 2 weeks; and selected tissues were analyzed for cations on an atomic absorption spectrophotometer. Mg values are presented here.Individual Mg concentrations in vitreous humor and soft tissues overlapped between control and Mg-deficient, groups, but in bone were distinctly separate. One bone should be consistently analyzed. Support: Missouri Heart Assoc. and the Life Seekers, St Louis.