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Metastatic carcinoma from unknown primary site.

Snee and Vyramuthu (1985) report the clinical course and impact of treatment of patients presenting with metastatic carcinoma from an unknown primary site. In the treatment of bone pain by local radiotherapy they suggest from a retrospective review of the case notes that fractionated radiotherapy is superior to single-dose treatment, with a response of 90% compared with only 25%, respectively.