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Instrumentation for subsurface imaging in a clinical environment

The aim of this effort is to test the feasibility to develop endoscopic optical imaging technology for cancer screening inside the human body. The degree of success of such optical imaging instrumentation depends on the presence of optical differences among the various tissue components of interest of a body part or organ. Our research approach involves the utilization of the spectral polarization difference imaging technique incorporated into endoscopic imaging modalities. To establish methodology for optimum operation, we have built a compact imaging system for in vitro studies of human tissue samples of interest in a clinical environment.