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[Meteorologic effects and thrombocyte aggregation in patients with myocardial infarct living in the coastal region of central Dalmatia].

The circulating platelet aggregates were measured in 90 patients admitted to the Clinical Hospital Split because of myocardial infarction developed in the costal region of Middle Dalmatia. They were divided into three groups, each consisting of 30 patients affected by coronary incident developed during the three most characteristic weather types in the region: sirocco, bora and calm weather. All the patients have had elevated values of circulating thrombocyte aggregates, but the patients in the sirocco group exhibited significantly higher values (34.77% +/- 11.67%) than the patients in both bora (27.93% +/- 11.72%; p < 0.05) and the calm weather groups (23.5% +/- 10.62%; p < 0.01). In the control group of 10 healthy examinees the values of circulating platelet aggregates were within normal range during all the three weather types (5.85% +/- 0.70%, 5.24 +/- 0.51% and 5.18 +/- 0.59%, in case of sirocco, bora and calm weather, respectively). The three groups were not significantly different regarding the values of creatinine kinase, which means that the infarct size was not the probable cause of the observed differences in platelet aggregability. Taking into account our previous finding of increased incidence of coronary events during sirocco, these results suggest that increased platelet aggregability is a contributing factor to the risk of myocardial infarction during such a weather.