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Advances in research into the preparation and biological activity of maslinic acid.

Maslinic acid, a pentacyclic triterpene acid, is mainly isolated from olives. Maslinic acid and its derivatives exhibit a broad range of biological properties, such as anti-inflammatory, anti-cancer, anti-diabetic, antimicrobial, neuroprotective and hepatoprotective activities. In this mini-review, the progress of research into maslinic acid with regard to its bioactivities, extraction, semi-synthetic preparation and patents is reported. The relationships between the structure and the activity of maslinic acid and its derivatives are also discussed.