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Is Primary Aldosteronism Underdiagnosed In Clinical Practice?

1. Primary aldosteronism is a syndrome consisting of hypertension, suppressed renin activity or concentration and high aldosterone levels in plasma or urine. The main steps in diagnosis are the determination of renin and aldosterone levels, the demonstration of renin–aldosterone dissociation and discrimination between idiopathic hyperplasia and Conn’s adenoma, with only Conn’s adenoma amenable to surgery.