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Proceedings of the Society of British Neurological Surgeons

meningiomas are more common in women and may enlarge or become symptomatic during periods of hormonal flux. Also that there is an increased incidence of meningioma in patients with breast cancer, a tumour known to contain steroid hormone receptors, and which may respond clinically to hormonal manipulation. Their studies were stimulated by the view that because excision of meningiomas is not always possible and up to 20% of the tumours recur, a method for inhibiting renewed growth of these tumours is needed. Oestrogen receptors (ER) and progesterone receptors (PR) were measured using an isoelectric focusing technique. Competitive binding experiments confirmed the specificity of the assays, which were unaffected by dexamethasone. Qualitative and quantitative histological analysis