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Optical coherence tomography (OCT) of human skin with a slow-scan CCD camera

The purpose of this research is to try to investigate and improve the possibilities of optical coherence tomography for evaluation and imaging of melanoma. As approaches to reach this aim by photo diode detection were not successful, we suggest making an experimental setup with a slow-scan CCD-camera that is able to detect very little numbers of photons. The interferometric arrangement had to be adapted to the quite bad signal-to-noise ratio of the camera. First measurements were made on models consisting of very small glass spheres embedded in polyester resin. It was possible to prove coherent photons from a depth of 2 mm. Objects could be found up to 1 mm depth.