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[Clinical studies of cefotiam in the field of otorhinolaryngology].

Cefotiam (CTM) was intravenously given to 20 patients with infections in the field of otorhinolaryngology. Daily doses of CTM were 2 to 4 g divided into 2. Clinical responses were excellent in 11 patients, good in 8 and fair in 1, the rate of satisfactory clinical responses being 95% (19/20). Ninety-one % (10/11) of Gram-positive cocci isolated from the patients were eradicated by the CTM treatment, while 60% (6/10) of Gram-negative bacilli were persisted. As for the side effects, eruption and elevation of GOT and GPT were observed in 1 patient.