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Mirtazapine for Major Depression Developed After Hyperemesis Gravidarum.

reviews also found that tirofiban-induced thrombocytopenia usually resolved after a mean of 2.1 days and disappeared within a week.6,8 Interestingly, in our case, considering the patient had no history of hemorrhagic disease and the CRUSADE Bleeding Score was 22 scores (very low risk of bleeding) on admission, we did not give a platelet transfusion for the patient. Despite the platelet count vanished at the onset of thrombocytopenia and rose slightly in the first 24 hours, we only observed minor bleeding in the skin, urinary tract, and alimentary tract and recovered 48 hours later. Besides, during the treatment, the antiplatelet drugs were discontinued, and supportive treatment was maintained. Finally, the platelet count exceeded 100 3 109/L on day 7 and without obvious bleeding during this period. In fact, our case may provide the following important experiences: (1) a case of acute, extremely profound, and life-threatening thrombocytopenia after tirofiban administration without severe bleeding was reported; (2) the platelet count recovered spontaneously without platelet transfusion; (3) the tirofiban-induced thrombocytopenia seemed to be easily resolved by the interruption of antiplatelet drugs and early supportive treatment; and (4) the early discovery of tirofiban-induced acute profound thrombocytopenia is very important. Therefore, our report emphasizes the need for routine testing in all patients who were treated with tirofiban.