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Autologous Mixed Lymphocyte Reaction in Man

The proliferative response of T lymphocyte cultured with autologous non‐T lymphocyte is known as the autologous mixed lymphocyte reaction (AMLR). In AMLR. Both helper and suppressor functions are generated. In this investigation we have examined I cell proliferative responses in AMLR in 12 patients with bronchia asthma 10 patients with allergic rhinitis, and 10 patients with atopic dermatitis and compared that with simultaneously with bronchial asthma is significantly higher than that of health normals. However, AMRL response in patients with allergic rhinitis or atopic dermatitis is comparable to controls. Mechanisms for increased AMLR in patients with bronchial asthma are discussed.