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Time dynamics of cerebral blood flow during LBNP (1183.11)

Background: The time constant (τ) estimates how fast the arterial part of cerebral vascular bed is filled with blood volume during the cardiac systole. We have demonstrated previously that τ provides new insights into time dynamics in different cardiovascular diseases and during CO2 challenge in normal subjects. In this study we aimed to investigate time dynamics of cerebral blood flow using τ during progressive lower body negative pressure (LBNP) test.