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Nasal endothelial interleukin‐10 expression is negatively correlated with nasal symptoms after allergen provocation

Background:  Despite major efforts, factors that predict or correspond to the level of allergic symptoms remain elusive. Given our previous observations of mucosal interleukin‐10 (IL‐10) expression by local tissue cells and its described role as immune modulator, we hypothesized that, in allergic rhinitis, nasal mucosal IL‐10 expression could influence the severity of symptoms.