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Emerging human coronaviruses--disease potential and preparedness.

It is likely that novel zoonotic virus infections causing serious disease and death in humans will increasingly test our ability to respond appropriately. Changes in commercial and social practices, the environment, and travel will continually provide new opportunities for zoonotic pathogens to infect humans. In addition, ever more sophisticated tools to detect novel pathogens will increase the chance that we will identify sporadic infections that do not cause widespread disease. Zaki et al.1 now describe in the Journal the detection of a novel betacoronavirus (called HCoV-EMC) in a patient from Saudi Arabia who died of pneumonia and renal failure in . . .