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Chest radiographic abnormalities in Lennert's lymphoma

In reviewing the medical records of ten patients with Lennert's lymphoma, we found chest radiographic abnormalities in five cases. Two cases had hilar and mediastinal adenopathy without associated parenchymal or pleural disease, and three cases had isolated pulmonary parenchymal abnormalities. In one patient, both the chest radiograph and the histologic findings, obtained by open lung biopsy, mimicked miliary granulomatous disease. This article emphasizes the need to be alert to this aggressive T-cell neoplasm, since its clinical course differs significantly from some of the diseases it tends to imitate. By being aware of the entity and by using thorough pathologic and immunopathologic techniques, difficult cases of Lennert's lymphoma can be successfully diagnosed.