{'fraction_non_alphanumeric': 0.03216947822675559, 'fraction_numerical': 0.030992546096508436, 'mean_word_length': 5.028081584392551, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Knowledge, attitude, prevention practice, and associated factors toward COVID-19 among preparatory school students in Southwest Ethiopia, 2021

Introduction As of February 2021 COVID-19 report in 57 African countries, there were 3,761,512 confirmed cases and 98,088 deaths. Ethiopia reported the highest number of cases in East Africa with a total of 147,092 cases and 2,194 deaths. Over 1.5 billion students from 195 countries across the world separated from school as a consequence of the closure of schools related to the pandemic. This study aimed to determine the level of knowledge, attitude, prevention practices, and determinant factors regarding COVID-19 among preparatory school students in southwest Ethiopia. Methods An institution-based cross-sectional study design was used for 422 samples. Each respondent was selected using simple random sampling. Data were collected using a self-administered questionnaire. The collected data were entered and analyzed using Statistical Package for social science software version 25.0. Multivariable binary logistic regression was used to identify factors that were significantly associated with the practice of COVID-19 prevention. Results The response rate in this study was 96.2%. A higher proportion of the respondents were female (53.9%), Bench (43.6%), and protestant (47.3%). The level of good knowledge, positive attitude, and good practice were 81.8%, 70.9%, and 47.0% respectively. Using social media [AOR: 1.801, 95% CI: 1.005, 3.226], watching television [AOR: 1.884 95% CI: 1.093, 3.247], being knowledgeable [AOR: 5.173 95% CI: 2.276, 11.755], and having a positive attitude [AOR: 4.300 95% CI: 2.351, 7.868] were positively associated with COVID-19 prevention practice. Conclusion Despite the high level of knowledge and a moderate level of positive attitude, the practice of COVID-19 prevention measures was low. Using social media, watching television, being knowledgeable, and having positive attitudes towards COVID-19 increases the tendency to practice COVID-19 prevention measures. School directors and teachers should strictly monitor students for their adherence to COVID-19 prevention measures as directed by the local and national health care departments.


Results
The response rate in this study was 96.2%. A higher proportion of the respondents were female (53.9%), Bench (43.6%), and protestant (47.3%). The level of good knowledge, positive attitude, and good practice were 81.8%, 70.9%, and 47.0% respectively. Using social media [AOR: 1.801, 95% CI: 1.005, 3 Most human coronavirus infections can cause mild common cold-like symptoms and others may cause serious illnesses like SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome) [3].
As of February 14 2021, COVID-19 affected 235 countries which resulting in a total of 106,477,025 cases and 2,361,848 deaths worldwide. In Africa, 57 countries reported the case (3,761,512 cases and 98,088 deaths across the continent). Ethiopia reported the highest number of cases in East Africa with a total of 147,092 confirmed cases and 2,194 deaths as of 14 th February [4].
The main mechanism for person-to-person transmission of COVID-19 is through the droplets of saliva or discharge from the nose while the infected person sneezes or coughs. It can also be spread via direct or indirect contact with an infected person. Respiratory droplets or aerosols can penetrate the lungs via inhalation through the nose or mouth [1]. The spread of the organism can be halted by proper handwashing, maintaining physical distancing, avoiding touching faces with the hand, and covering mouth and nose with a face mask [5,6].
The hazard of the spread of infectious agents is high in social organizations with high-risk populations. The influence of transmission of the organism in such social organizations can be halted by the proper application of infection prevention and monitoring strategies [2].
To minimize the transmission rate of infectious agents, educational organizations in many countries around the world temporarily suspended face-to-face instruction. Schools in many countries have closed since early March 2020 [7]. Over 1.5 billion students from 195 countries across the world separated from school as a consequence of the closure of schools related to the pandemic. As a consequence, distance education was adopted. This may have an effect on the students negatively in different ways: less time spent on learning, development of depressive symptoms, change in the way of interaction, and lack of motivation for learning [7,8].
Despite decisions to re-open schools, there are several strategies in Ethiopia to decrease person-to-person transmission of the pandemic among students. This includes decreased contact hours with teachers and encouragement of digital learning. This strategy may negatively affect students through the inaccessibility to information and communication technologies [9].
A Study found some predictors of adherence to communities for COVID-19 outbreak prevention measures. This includes self-efficacy, perceived benefits, perceived barriers, and perceived susceptibility [10].
The World health organization adopted a one-year strategic plan called COVID-19 strategic preparedness and response plan (SPRP) to be applied from February 1 2021 to January 31 2022 which is intended to help direct the public health response to the pandemic at different phases and to update the worldwide strategic priorities to support this response [11].
Several studies have been undertaken to measure COVID-19 knowledge, attitude, and practice. These studies, on the other hand, looked at a specific group of people, such as communities, health care providers, chronic disease patients, university students, and confined people. Only a few studies have examined the elements that can influence COVID-19 prevention. The purpose of this study was to determine the level of COVID-19 knowledge, attitude, preventative practice, and determinant factors among preparatory school students in Mizan-Aman town, Bench-Sheko zone.

Study area and period
The study was conducted at the Mizan-Aman town secondary and preparatory schools. Mizan-Aman Town, the administrative center of the Benchi-Sheko zone, is located 574 km from Addis Ababa. It is located 227 km southwest of Jimma. There were three preparatory schools in the town. They provided services for a total of 2803 students, of them 1413 were male and 1390 were female. The data were collected from March 5 2021 to March 14, 2021.

Study design
A cross-sectional study design was used.

Study participants
All students registered in the Mizan-Aman town preparatory schools were the source population. Randomly selected students who fulfilled the inclusion criteria and were available during the data collection period were included in this study.

Sample size determination and sampling technique
The sample size for this study was calculated by using single population proportion formula. Hence study has not been conducted on the KAP of COVID-19 among preparatory students, we used a prevalence of 50% to obtain the largest possible sample size. Considering a 95% confidence interval and a 5% margin of error, the total sample size became 384. By adding a 10% non-response rate, the final sample size was 422.

Data collection instruments and procedure
Data were collected using a structured self-administered questionnaire. Information regarding sociodemographic data was collected using a structured self-administered questionnaire that was adopted after reviewing different kinds of literature [12]. The questionnaire was reviewed by research and community service experts. No major revision has been made on the tool. KAP towards COVID-19 prevention was assessed by using a students' KAP on prevention of COVID-19 (SKAPCOV-19) questionnaire. The tool contains 36 items: 18 Knowledge items, 6 attitude items, and 12 practice items.

Operational definitions
Preparatory school. An academic institution providing teaching-learning services for grade 11 and 12 students.
Knowledge. Those students who answered greater than or equal to the mean value of knowledge questions (�9 questions) by the SKAPCOV-19 questionnaire were considered as knowledgeable [13].
Attitude. Those students who answered greater than or equal to the mean value of attitude questions (�3 questions) by the SKAPCOV-19 questionnaire were considered as having a positive attitude [13].
Practice. Those students who answered greater than or equal to the mean value of practice questions (�6 questions) by the SKAPCOV-19 questionnaire were considered as having good practice [13].

Data quality assurance
Filled questionnaires were checked daily for errors and incompleteness. The data were collected by 4 data collectors (2 BSc Nursing and 2 BSc Public health). A two-day training was given for data collectors. Appropriate and pertinent instructions and directions were given for the data collectors to ensure the quality of data. The data collectors were supervised by an epidemiologist having MPH.

Data processing and analysis
The collected data were checked for completeness and errors. Each questionnaire was coded and the data was entered and analyzed by using SPSS software version 25.0. The entered data were cleaned and errors were corrected. Hosmer-Lemeshow goodness of fit test was checked for model fitness and to check the fulfillment of the assumption of binary logistic regression. Multivariable binary logistic regression analysis was done to check the association of explanatory variables with COVID-19 prevention practice. Variables with a P-value of � 0.05 in the multivariable binary logistic regression were considered a statistically significant determinant factor. Finally, the result of the study was summarized by using tables, graphs, and narrative descriptions.

Ethical consideration
Ethical clearance was taken from the Ethical Review Committee of Mizan-Tepi University College of medicine and health science, Mizan-Aman town. Permission was taken from school directors to conduct the study. The respondents were informed about the objective of the study and the confidentiality of the information would be kept. Voluntary written informed consent was taken from the participants and verbal consent was taken from the parents of students under the age of18 years through phone calls. The participants were also informed that there were no financial benefits and harms from being involved in the study. They were informed about the right to discontinue the study at any time.

Socio-demographic status of study participants
Out of the calculated 422 sample size, 406 have participated that yields a response rate of 96.2%. Among them 219(53.9%) were females and 187(46.1%) were males. The mean ages of the participants were 18.81±1.301 yrs. More than one-third, 177(43.6%), of the participants were Bench in ethnicity. Nearly half of the participants, 192(47.3%) were protestant in religion. The majority of participants, 340(83.7%), were unmarried ( Table 1).
More than half, 63.3%, of the participants agreed that handling COVID-19 will be difficult if people or the community not keeping up with the information related to preventions ( Table 3).

Discussion
According to this study, 81.8% of the students were knowledgeable towards COVID-19 which is in line with a cross-sectional study done in China undergraduate students and Cameroonian in which 82.34%, and 84.19% of the participants were knowledgeable towards COVID-19 respectively [14,15]. The result of this study is lower as compared with a study conducted in China and Ataye Hospital visitors in which 90% and 95.1% of the participants were knowledgeable towards COVID-19 respectively [16,17]. This may be due to a difference in source population and difference in sample size as such factors may influence findings. Whereas, the result of this study is higher as compared with a study conducted at Gondar city secondary school students [18], on Bangladesh residents, a study conducted among undergraduate students at Debre Birhan University, and a study conducted on quarantined individuals in Tigray which showed that 23.5%, 48.3%, 73.8%, and 42.9% of the participants had accurate knowledge towards COVID-19 respectively [19][20][21]. It is also higher as compared with a study done on Jimma University medical center visitors which showed that 41.3% of the participants had a high knowledge level towards COVID-19 [22]. This difference may be due to a difference in the time at which the studies were conducted. The level of knowledge may be higher in recent studies due to disseminated information regarding the outbreak as it is a great public and government concern. According to this study, 70.9% of the respondents had a positive attitude towards COVID-19, which is similar to a study conducted on Vietnamese [23] and with a report from Ethiopia [24] in which 68.6% and 72.9% of the participants had a positive attitude towards COVID-19 respectively. The result of the study is lower as compared with a study conducted in Malaysia which showed that 83.1% of the respondents had a positive attitude towards COVID-19 [25]. This difference may be due to a variation in the source population on which the study was conducted. However, the result of this study is higher as compared with a study conducted in Uganda which showed that 51.3% of the participants had a positive attitude towards COVID-19 [26]. It is also higher than a study conducted in Sidama regional state that showed 37.5% of the respondents had a positive attitude towards COVID-19 [27]. This may be due to a difference in the time at which the studies were conducted. An expanded health education program by the government and other non-governmental organizations may trigger the development of a positive attitude by the population. According to this study, 47.0% of the respondents had good practice of COVID-19 prevention which is similar to studies conducted at Addis Zemen Hospital of Northwest Ethiopia and among Dessie city residents in which the prevalence of good practice was 52.7% and 44.6% respectively [13,28]. The level of COVID-19 prevention practice by this study is slightly lower than those studies conducted among Dessie health center visitors and Amhara region health care workers in which 58.3% and 62% of the participants had good COVID-19 prevention practice [29,30]. The level of practice determined by this study is markedly lower as compared with a survey conducted on undergraduate students in China in which 87.94% of the respondents had a proactive COVID-19 prevention practice [14]. This may be due to a difference in geographical location and sample size. As the outbreak was originated in China, several interventions and strategies by the government of China may influence the COVID-19 prevention practice. In another way, a difference in sample size affects the result of a study in which the larger sample size results in a more accurate determination of findings. The finding of this study is higher as compared with a study conducted at Oromia Special zone surrounding Finfinee [31] and on adult populations of Sidama regional state [27] in which 31.0% and 24.4% of the respondents adhered to COVID-19 prevention measures respectively. This may be due to a difference in source population in which students may be more likely to apply COVID-19 prevention measures as schools commenced rules and regulations regarding COVID-19.
According to this study, watching television has a statistically significant association with COVID-19 prevention practice in which students watching television were more likely to practice COVID-19 prevention measures. Several messages regarding COVID-19 are being broadcasted through different television channels and it will serve as one way of creating awareness towards the outbreak. Such messages may trigger the population to practice COVID-19 prevention measures.
Students who were social media users were more likely to practice COVID-19 prevention measures. This is similar with a study conducted in Jordan in which only small proportion of adolescents were engaged in risky practice while majority of them having information through social media and Television [32]. As it is known, social media have a great impact to alter the community towards a certain behavior. Different government and private social media channels disseminate messages towards the precaution of the COVID-19 outbreak.
According to this study, knowledge towards COVID-19 has a statistically significant association for prevention practice in which respondents who were knowledgeable regarding COVID-19 were more likely to practice COVID-19 prevention measures which is similar to a study conducted on Vietnamese and on Ataye Hospital visitors [17,23]. The finding is also similar to a study conducted on quarantined patients in Tigray in which knowledgeable individuals were more likely to avoid traveling to crowded places, to wear a mask, and to apply strategies directed by the local health care authorities [21]. A study conducted on Jimma Medical center visitors also showed that respondents with good COVID-19 knowledge were more likely to wash hands frequently and to avoid handshaking [22]. This may be due to the effect of being knowledgeable towards the cause, transmission, and prevention of COVID-19 for the application of prevention measures. As someone becomes aware of the cause, transmission, and prevention of the disease, the more likely he/she apply COVID-19 prevention measures.
According to this study, attitude towards COVID-19 have a statistically significant association with COVID-19 prevention practice in which students having a positive attitude were more likely to have good COVID-19 prevention practice. The finding of this study is similar to a study conducted in China on undergraduate students which found a positive correlation between attitude and prevention practice of COVID-19 [14]. This may be due to the effect of positive feelings towards the prevention of COVID-19 for being adhered to prevention measures. As someone has felt positive towards prevention of the disease, the more likely he/she apply COVID-19 prevention measures.

Implications of the study
The findings from this study provide baseline information regarding the KAP of preparatory students regarding COVID-19. As COVID-19 is the burning issue globally, the findings will guide policymakers, governmental and non-governmental organizations, to design strategies accordingly. It also directs the local health department to select the appropriate way for transmitting COVID prevention and precaution messages and to identify different constraints for the application of COVID prevention measures. The findings of this study will serve as a baseline for other researchers interested in related issues.

Limitations of the study
Hence self-administered questionnaire was used, it is impossible to look for the feeling of the respondents while answering the questions. As a cross-sectional study assesses the causes and effects simultaneously, it may not show a perfect cause-effect relationship. On the other hand, the findings of this study may not be representative of other countries with different socioeconomic characteristics as a result of a difference in the degree of impact of the pandemic and may not be generalizable for a population with different socioeconomic classes.

Conclusion
This study found that there was a high level of knowledge and a moderate level of a positive attitude toward COVID-19 among preparatory students. However, the practice of COVID-19 prevention measures was low.
Using social media and watching television increases the tendency of the students to practice COVID-19 prevention measures. Being knowledgeable and having positive attitudes towards COVID-19 by the students increases the chance for proper practice of COVID-19 prevention measures. The federal ministry of health and other governmental and non-governmental organizations should strengthen the transmission of messages concerning COVID-19 through social media and other national public Media. School directors and teachers should strictly monitor the students for their adherence to the COVID-19 prevention measures as directed by the local and national health care departments.