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Bilateral cavernous sinus thrombosis following community-acquired methicillin-resistant staphylococcus aureus infection: a case report and review of the literature.

OBJECTIVES
We describe a case of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) skin infection leading to bilateral cavernous sinus thrombosis (CST) and subsequent left eye blindness in a previously healthy, immunocompetent woman. A secondary objective is to document all published cases of MRSA induced CST.


DATA SOURCE AND STUDY SELECTION
To identify all relevant publications on MRSA-induced CST in adults.


RESULTS
Seven publications were included in this review describing patients age 19 or older. Together, with the case included in this publication, a total of 8 cases of MRSA induced CST have been documented since 2003. Of interest, to our knowledge this is the first reported case of CA-MRSA CST temporally associated with nasal H1N1 vaccination.


CONCLUSION
In selecting empiric antibiotic coverage for septic CST, the practitioner should use antibiotics that are active against CA-MRSA to help prevent morbidity and mortality.