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[Electron microscopic and immunological study of influenza virus interaction with murine peritoneal microphages].

Electron microscopic and immunological investigations of influenza virus HONI interactions with peritoneal macrophages of intact and immune mice were carried out. Both intact and immune macrophages exert phagocytosis and disintegration of virions in phagolysosomes as early as 10 and 30 min after the end of adsorption. This process is most active with eosinophils, less in neutrophils and the least in basophils. Titration of the infectious virus in chick embryos showed that immune macrophages contained considerably less virus than the intact ones.