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Blood–brain communication Essential for regulation of autonomic nervous system and optimal health?

control centre of our body. It collects and integrates critical information coming from the internal and external environment, and initiates appropriate physiological responses to maintain the internal environment in a homeostatic state, supportive of optimal health. Internal information regarding body functions comes from a variety of sensors including thermoreceptors (heat), baroreceptors (pressure), chemoreceptors (substances), as well as those monitoring fluid volume, metabolic state, and immune function. Autonomic control centres within the brain collect and integrate this information and initiate appropriate autonomic responses to maintain this essential ‘milieu interieur’.