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Equilibrium radionuclide ventriculography in Duchenne's cardiomyopathy

Rest and stress (handgrip) equilibrium radionuclide ventriculography was performed in 20 patients with Duchenne muscular dystrophy. The mean value of LVEF was normal, but two patients showed values below 35% and another two patients values over 70%. Mean regional wall motion values were less than 2 in lateral (posterior and inferior) and septal walls. Handgrip usually produced a reduction of LVEF and regional wall motion: in three cases severe decrease of motility was observed. Equilibrium ventriculography appears to be useful in the selection of patients with high functional cardiac involvement, integrating the characteristic ECG and echography, and, perhaps, in the assessment of myocardial tolerance to physical therapy.