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A rare adverse drug reaction of imatinib mesylate

A 45‐year‐old postmenopausal female came to the outpatient department with the complaints of upper abdominal pain and weight loss of 2 months duration. On examination, she had splenomegaly (4 cm size from the costal margin). Complete blood examination showed increased leukocyte count including mature myeloid cells and myeloid precursors [Figure 1]. fluorescent in situ hybridization revealed the presence of philadelphia chromosome [t(9;22)]. She was diagnosed with a case of CML‐CP and was started on imatinib mesylate 400 mg once daily orally.