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[Circulating tissue antigens in inflammatory heart disease].

Experiments with an antipericardium immune serum of the goat resulted in the proof of two not identical with serum proteins antigens in the pericardium. By means of the same antiserum with the help of the gel diffusion technique after Ouchterlony and immunoelectrophoresis the sera of patients with carditis or myocardial infarction, respectively, were examined for the presence of circulating tissue antigens. In 20 out of 23 patients with carditis 1 or 2 antigens were found which were not identical with normal serum proteins. In 27 cases of myocardial infarction their proof was successful only in 4 patients, in complication by a post-myocardial infarction syndrome in 2 out of 3 cases. In comparative investigations of sera of 100 healthy persons only 4 test persons showed a positive result. There was no clue for the identity of one of the antigens proved with C-reactive protein.