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[Impact of the Epstein Barr virus on gastric cancer in Peru].

Epstein Barr Virus (EBV) is responsible of 10% of Gastric Cancer (GC), correlating with better survival rates. In Peru, there were not studies about prevalence and clinical characteristics of CG EBV positive.


OBJECTIVE
Determine prevalence and clinicopathological characteristics of GC EBV positive.


MATERIALS AND METHODS
111 GC tumour samples were centrally screened by Chromogenic in situ hybridization (CISH) technique for EBV-encoded RNA (EBER) transcript.


RESULTS
8.4% of cases were positive for EBV. Most cases EBV positive were more than 60 years old; male, antrum/pylorus had more frequent localizations. Most cases had an intestinal type and tubular patter and a tendency to better prognostic in comparison EBV negative cases.


CONCLUSION
EBV positive GC is an entity with a prevalence of 8.4% in Peru with distinctive clinical and morphological characteristics.