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Comprehensive two-dimensional gas chromatography advances in technology and applications - biennial update.

Apart from the pure methodological process of implementing a comprehensive two-dimensional gas chromatography (GC×GC) method, surely it is the excitement engendered by a well-designed separation that has captured the attention, fascinated and sustained proponents and users throughout the decades since Liu and Phillips1 were equally enthralled by what they produced, the first time they witnessed their result. This technology update largely addresses developments over the last 2 years (late 2017 - 2019) since the Synovec group presented their review.2 Progressive advances in instrumentation, software and data analysis tools, fundamental relationships and capabilities, and the numerous repertoire of applications to which GC×GC methods have been applied will be included. We attempt to offer an insight into the dynamic nature of the field, and hopefully many newer converts to the field will be recognized for their emerging interest and contributions.