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Primary malignant melanoma of the adrenal gland.

PRIMARY MELANOMA OF THE ADRENAL gland is rare. A review of the English literature yielded 17 cases, of which only 5 cases contained adequate documentation.1-5 This article reports a new case, identified by immunohistochemical and ultrastructural methods, and offers a critical review of the literature to evaluate data and criteria that will enable primary melanoma to be recognized as a distinct entity and to be distinguished from pigmented pheochromocytoma.