{'fraction_non_alphanumeric': 0.015223596574690771, 'fraction_numerical': 0.0, 'mean_word_length': 6.060402684563758, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Effect on synthetic capacity of antibodies directed against receptors of allotype-bearing rabbit cells.

Rabbit immunoglobulin molecules possess antigenically distinct allotypic markers. Immunoglobulin molecules possessing such markers which are attached to the surfaces of lymphocyte precursors of antibody-forming cells are believed to serve as antigen receptors. Interactions between allotypic determinants and antibodies directed against them can provide useful models for the study of immunoregulatory phenomena. Exposure of a fetal or neonatal rabbit to antibodies against one of its immunoglobulin allotypes results in a persistent defect in expression of that type (allotype suppression). Some evidence indicates that this phenomenon involves specific active suppression by lymphoid cells. By examining the effects of anti-allotype antibodies on allotype-bearing lymphocytes in vitro, certain specific events surrounding the processes of lymphocyte ontogeny, and the differentiation and maturation of antibody-forming cells are being analyzed.