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Drug Discovery from Peruvian Medicinal Plants for the Treatment of Psychosis

Schizophrenia is a severe mental disorder that affects approximately 1% of the population. The main symptom is psychosis in which thought and emotions are impaired. Current pharmacological treatments for schizophrenia are partially effective and its long term intake causes side effects. In Peru, native communities since ancient times have considered the psychosis like “madness” and they have treated it using preparations from natural products. The Peruvian traditional medicine is a potential source of drugs because its effectiveness, possible low side effects and they could be acting on different molecular mechanisms compared to the current drugs on the market.