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Chromosome Segregation and Cell Division Defects in recBC sbcBC ruvC Mutants of Escherichia coli

ABSTRACT The RuvC protein is important for DNA recombination and repair inEscherichia coli. The present work shows that aruvC null mutation introduced into a recBC sbcBC background causes severe defects in chromosome segregation and cell division. Both defects were found to result from abortive recombination initiated by the RecA protein.