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Clinicopathological problems of the local tissue effect of IUDs containing copper. III. Cytochemical study of the endometrial scrapings.

The clinicopathological problems of the tissue effect of copper-containing IUDs are discussed. In the third part of their series, authors present the cytochemical analysis of the endometrial scrapings. For the investigations, dithizone, salicylaldoxime, rubeanic acid as well as dimethylglyoxime were used. The reaction precipitate, the copper dithizone complex, could be visualized partly intracellularly and intramitochondrially and partly interstitially. The technical problems of copper demonstration are also dealt with.