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Alterations in systemic levels of Th1, Th2, and Th17 cytokines in overweight adolescents and obese mice

Obesity represents a major problem for patients and health care systems in most industrialized countries. A chronic inflammatory state in obese individuals leads to disease conditions associated with activation of cellular immune mechanisms. Here, we sought to investigate the role of Th1‐, Th2‐, and Th17‐related cytokines in overweight adolescents and mice on a high‐fat diet.