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NADH-fluorescence in medical diagnostics: first experimental results

Using efficient pulse lasers as excitation sources, low-loss flexible light pipes for signal transmission, very sensitive photodetectors, fast electronic circuits, and computing techniques the authors built a versatile measuring apparatus. It consists of a main frame for housing the optical and electronic components, a personal computer, and a fluorescence-measuring head which is connected to the main frame by a flexible fiber cable. The paper shows examples of how such a device can be applied for different diagnostic purposes.