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Comparison of Once Daily Atenolol with Slow Release Oxprenolol in Hypertension

One of the most practical advances in the management of hypertension has been the realization that some drugs may be effective if given once daily. Different beta-blocking drugs given in multiple daily doses are probably equally effective in lowering blood pressure if equivalent doses are used, and this has usually been judged by their ability to reduce an exercise tachycardia. It is therefore important to know if this is true when given in a single daily dose. A small initial study has been carried out to compare the effects on blood pressure control of once daily slowrelease (SR) oxprenolol and once daily atenolol.