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Comparative study of copper, zinc levels in uncontrolled type 2 diabetes mellitus with normal subjects

accounts for majority of the cases, can lead to multiorgan complications. Direct association of minerals  , Trace elements and vitamins in the pathogenesis and natural cause of  type 2 diabetes mellitus has been observed in many research studies. Aim: To estimate the levels of Copper , Zinc and HBA1c in uncontrolled Type 2 Diabetes mellitus patient. Material and methods: A cross sectional analytical studies was conducted in DR B R AMC. Study group included 40 known case of uncontrolled Diabetes mellitus. Results: In the present Study serum copper levels in uncontrolled Type 2 Diabetes Mellitus patients was 204.3 ± 49.0 and in controls it was132.4 ± 20.2. There was a statistically significant increase in the mean copper values in uncontrolled Type 2 Diabetes Mellitus patients  (P< 0.0001). Serum Zinc levels in uncontrolled Type 2 Diabetes Mellitus patients was 174.7 ± 31.0  µg/dl and in the controls it was 207.4 ± 36.6 µg/dl. There was a statistically significant decrease in the mean Zinc values  (P<0.0001).  Conclusion: Trace elements play a vital role in maintaining the normal metabolism and homeostasis. 