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Inducibility of germ-tube formation in Candida albicans at different phases of yeast growth.

Summary: Yeast cells of Candida albicans growing at 25 °C in glucose/yeast extract medium cannot germinate by dilution into fresh medium at 37 °C before reaching the stationary phase of growth. However, cells at any stage of growth are able to form germ-tubes giving true hyphae when incubated at 37 °C in the presence of inducers such as serum or N-acetyl-d-glucosamine. Thus, stationary phase cells are not endowed with a specific ‘competence' to germinate.