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Cardiac liposarcoma and bilateral ovarian mature teratoma in a patient with congenital heart disease and f‐anisosplenia

A 10‐year‐old female with atrial septal defect presented with bilateral ovarian mature cystic teratomas. Three spleniculi adjacent to the main spleen were noticed while the endoscopic surgery. Two years later a heart tumor was discovered which led to death. Pathologic examination of samples of the mass proved it to be a liposarcoma. The unusual combination of atrial septal defect, f‐anisosplenia (female, congenital heart disease, multiple unevenly‐sized spleens, left lung type pulmonary isomerism), bilateral ovarian mature cystic teratomas and liposarcoma of the heart appears to be a unique presentation. Pediatr Blood Cancer 2008;51:304–305. © 2008 Wiley‐Liss, Inc.