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Multiparametric magnetic resonance imaging findings in men with low‐risk prostate cancer followed using active surveillance

Up to 35% of men on active surveillance (AS) for clinically localized prostate cancer will experience biopsy reclassification during follow‐up. Currently, annual prostate biopsy is recommended in AS programmes. Multiparametric MRI has shown promise in identifying men at risk for immediate reclassification at the time of entry into AS; however, the MRI characteristics of men already enrolled in AS who may be at low risk for disease reclassification have not been fully described. In the present study, we describe the MRI findings of a cohort of men enrolled within AS, with extended follow‐up. Among these men, multiparametric MRI demonstrated excellent specificity (0.974) and negative predictive value (0.897) for the detection of pathological index lesions (determined on serial biopsies). These results suggest that men enrolled in AS with a non‐suspicious MRI are unlikely to harbour an index cancerous lesion.