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Skeletal responsiveness to parathyroid hormone in healthy females: relationship to menopause and oestrogen replacement

In order to directly evaluate the role of parathyroid hormone (PTH) and Its Interaction with oestrogens for postmenopausal bone loss, studies were performed where synthetic human (1–38) PTH was Infused s.c. over 24 h in 15 healthy females. Measurements were made of serum electrolytes, PTH and biochemical Indices of bone turnover: serum osteocalcin and alkallne phosphatase and fasting urinary hydroxyproline and calcium.