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Bath‐water compared with oral delivery of 8‐methoxypsoralen PUVA therapy for chronic plaque psoriasis

Summary Forty‐four patients with chronic plaque psoriasis were randomly allocated to treatment with bathwater‐delivered 8‐methoxypsoralen (bath 8‐MOP) or oral 8‐methoxypsoralen (oral 8‐MOP) PUVA therapy. There was a significant reduction in extent of the lesions and psoriasis area and severity index (PASI) after 20 treatments with each modality. There was a fourfold reduction in cumulative ultraviolet A (UVA) dose in the bath group. Side‐effects of erythema and nausea were less with bath therapy.