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Control of multidrug-resistant microorganisms

This chapter discusses the burden and impact of antimicrobial resistant (AMR) bacteria on human health. It describes the types of antibiotic resistance, and the various factors which are responsible for promoting the emergence and spread of multidrug-resistant organisms (MDROs) in the healthcare facility. The chapter provides advice on how to successfully implement an antibiotic stewardship programme in hospital and strategies to promote prudent antibiotic prescribing. The role and responsibilities of the antimicrobial management team is also discussed. It provides a summary and characteristic of most commonly encountered MRDOs in a healthcare facility and provide practical advice on how to prevent and control the spread of methicillin-resistant Staph. aureus (MRSA), vancomycin-resistant Enterococcus (VRE), extended-spectrum beta-lactamases (ESBLs), carbapenem-resistant Enterobacteriaceae (CRE), and multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii.
