{'fraction_non_alphanumeric': 0.038346753758657585, 'fraction_numerical': 0.015766653527788728, 'mean_word_length': 5.349481587415087, 'pattern_counts': {'":': 0, '<': 4, '<?xml version=': 0, '>': 1, 'https://': 2, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 1, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
The COVID-19 Pandemic Mental Health Questionnaire (CoPaQ): psychometric evaluation and compliance with countermeasures in psychiatric inpatients and non-clinical individuals

Background The COVID-19 pandemic has greatly impacted people’s lives across a broad spectrum of psychosocial domains. We report the development and psychometric evaluation of the self-report COVID-19 Pandemic Mental Health Questionnaire (CoPaQ), which assesses COVID-19 contamination anxiety, countermeasure necessity and compliance, mental health impact, stressor impact, social media usage, interpersonal conflicts, paranoid ideations, institutional & political trust, conspiracy beliefs, and social cohesion. Further, we illustrate the questionnaire’s utility in an applied example investigating if higher SARS-Cov-2 infection rates in psychiatric patients could be explained by reduced compliance with preventive countermeasures. Methods A group of 511 non-clinical individuals completed an initial pool of 111 CoPaQ items (Open Science Framework: https://osf.io/3evn9/) and additional scales measuring psychological distress, well-being, and paranoia to assess construct validity and lifetime mental health diagnosis for criterion validity. Factor structure was determined by exploratory factor analyses and validated by conducting confirmatory factor analysis in the accompanying longitudinal sample (n = 318) and an independent psychiatric inpatient sample primarily admitted for major depressive-, substance abuse-, personality-, and anxiety disorders (n = 113). Internal consistency was assessed by Cronbach’s Alpha and McDonald’s Omega. For the applied research example, Welch t-tests and correlational analyses were conducted. Results Twelve out of 16 extracted subscales were retained in the final questionnaire version, which provided preliminary evidence for adequate psychometric properties in terms of factor structure, internal consistency, and construct and criterion validity. Our applied research example showed that patients exhibited greater support for COVID-19 countermeasures than non-clinical individuals. However, this requires replication in future studies. Conclusions We demonstrate that the CoPaQ is a comprehensive and valid measure of the psychosocial impact of the pandemic and could allow to a degree to disentangle the complex psychosocial phenomena of the pandemic as exemplified by our applied analyses. Supplementary Information The online version contains supplementary material available at 10.1186/s12888-021-03425-6.


Introduction
The COVID-19 pandemic and related governmental restrictions and recommendations to contain the rapid spread of the coronavirus (e.g., stay-at-home orders & social distancing) have greatly changed people's lives. Early on, news outlets and initial research have cautioned that the COVID-19 pandemic would affect and be affected by a number of key aspects of individuals' lives. These aspects include mental health and pandemic-related stress, risk and protective factors (contamination anxiety, social media usage, interpersonal conflicts, mental health-protective behaviour), and individuals' perception of the political handling of the crisis (conspiracy beliefs, political and institutional trust, and support of public health directives; e.g. [1][2][3],). We developed the COVID-19 Pandemic Mental Health Questionnaire (CoPaQ) in order to capture this wide pandemic-related psychosocial spectrum applicable for different study populations. The self-report questionnaire was published on the Open Science Framework (OSF; https://osf.io/3evn9/) in German and English early on in the pandemic in April, 2020 [4]. Since then, the instrument has received recognition from the wider research community worldwide with translations into Spanish, Croatian, Portuguese, Greek, Hungarian, Korean, Nepalese, Czech, and Romanian illustrating that the questionnaire has been well received and was applied frequently in different countries and study populations. To date, however, a psychometric validation of the CoPaQ has been lacking.
The present study aims to provide a comprehensive description and psychometric evaluation of the CoPaQ. We recruited a group of non-clinical individuals online (n = 511) and psychiatric inpatients from the LMU Biobank study (n = 113). They completed the CoPaQ and validated self-report measures on psychological distress, wellbeing, and paranoia. To determine the factor structure, selection of items, and model fit, we applied exploratory factor analyses (EFA) in our non-clinical derivation sample. We then evaluated this factor structure by applying confirmatory factor analyses (CFA) using accompanying longitudinal 10-week follow-up data (n = 318) and separate CFA for the psychiatric inpatient sample. Internal consistency was determined using McDonald's Omega and Cronbach's Alpha across samples. For selected subscales of the CoPaQ, we evaluated criterion-and construct validity.
In addition to the psychometric validation of the CoPaQ, we illustrate the questionnaire's utility in an applied research example. Previously, two large US cohort studies have suggested that patients with a history of mental disorders have an increased risk for SARS-Cov-2 infection even when controlling for important socioeconomic and health-related factors [5,6]. The authors suggest that one explanation for the increased risk of SARS-Cov-2 infection could be patients' lower compliance with public health directives (hygiene measures, social distancing guidelines, and political restrictions). However, this hypothesis and potential explanatory factors have not been investigated empirically.
A number of factors have been associated with individual differences in levels of compliance in the public with governmental guidelines. Higher levels of an individual's risk perception [7][8][9] as well as political and institutional trust [10] have been found to increase support for governmental regulations. Contrary to this, erroneous conspiracy beliefs about the origin of the coronavirus have been associated with reduced adherence to preventive measures [2]. Consequently, multiple plausible and partly diverging hypotheses could explain potential differences in support of governmental restrictions and regulations between psychiatric patients and non-clinical individuals. First, lower levels of trust may promote less adherent behaviours in psychiatric patients, which may be reflected in lower levels of COVID-19 institutional & political trust and higher levels of COVID-19 conspiracy beliefs and paranoid ideations, compared to non-clinical individuals. Conversely, psychiatric patients' adherence to COVID-19 countermeasures could be greater than in non-clinical controls as patients may exhibit higher levels of COVID-19 contamination anxiety, more COVID-19 physical risk factors, and overall greater general anxiety symptoms. These fear-related characteristics could promote protective behaviours against SARS-Cov-2 infection as reflected in higher levels of COVID-19 contamination anxiety, COVID-19 physical risk factors and general anxiety symptoms, compared to non-clinical individuals. Here, psychiatric patient populations may differ in their levels of mistrust, which is most characteristic for psychotic disorders and fear, which is most characteristic for anxiety disorders. In this study, we focused on a transdiagnostic psychiatric inpatient sample from all major diagnostic categories with most prominent prevalence of major depressive-, substance abuse-, personality-, and anxiety disorders. Testing these hypotheses requires the assessment of a number of COVID-19 related psychosocial domains, which provides the ideal setting to explore the utility of the CoPaQ questionnaire in the context of our case-control sample.

CoPaQ construction
The initial item pool was devised by the study team (psychiatrist and clinical psychologists) based upon clinical experience, reference to the current diagnostic classification system of Diagnostic And Statistical Manual Of Mental Disorders, fifth edition [11], reference to existing measures [12], and an extensive internet search for current media and research outputs [13][14][15][16]. Thereafter, each item was evaluated with regard to its face and content validity by independent experts (two examinees). A final construct of questions was designed, ensuring no overlap. Due attention was given to ensure that the questions were framed in simple language, and worded positively, with no ambiguity.
The first part of the questionnaire served to characterise the population under study by asking about SARS-Cov-2 infection status, COVID-19 physical health risk factors (self/others), employment status, health insurance status, life time mental health diagnosis, etc. The subsequent item pool was devised to reflect the following COVID-19related constructs: contamination anxiety (9 items), necessity of and compliance with countermeasures (29 items), mental health symptomatology (25 items), positive coping (12 items), stressors (29 items), interpersonal conflicts (5 items), social media usage (7 items), political and institutional trust (6 items), paranoid ideations (5 items), conspiracy beliefs (7 items), and social cohesion (6 items). The time period for all the items was either relating to the present moment or the previous 2 weeks. Items were rated on a 0 (not at all) to 4 (very much) scale.
We disseminated the questionnaire to the wider research community prior to validation to facilitate its use during the rapidly unfolding events during the pandemic.

Participants
To extract the items for the new measures of the psychosocial impact of the COVID-19 pandemic, a derivation sample of 511 participants from the general German population completed the full item pool (mean age = 30.12, SD = 11.15, female = 400, male = 110, diverse = 1). The derivation sample is part of an ongoing longitudinal survey into the mental health consequences of the pandemic. The subset of individuals who provided data for a second time (n = 318) formed our longitudinal validation sample (mean age = 30.54, SD = 11.28, female = 249, male = 68, diverse = 1). There were no significant differences between derivation sample and longitudinal validation sample in terms of age, sex, marital status, ethnicity, or employment status (p > .05). A second cross-validation sample consisted of 113 psychiatric inpatients (mean age = 43.93, SD = 14.64, female = 55, male = 58) recruited from the LMU Biobank study.

Procedure
Non-clinical participants were recruited online via social media advertisements (Facebook) and university mailing lists to participate in the survey including the CoPaQ and other questionnaires (see below). The survey was run using the secure online LimeSurvey software. A forced response format was applied and only complete responses were included in the current analyses (n = 592). We excluded participants who gave incorrect responses to more than one out of three included bogus items (e.g., "Please, indicate completely agree"; n = 47) and with response times < 25 min, which we considered highly unlikely (median completion duration = 48 min; interquartile range [IQR] = 38-60; n = 7). At the end, by entering their email addresses participants had the opportunity to be included in a prize draw and take part in the 10-week follow-up assessment. Those participants at the 10-week follow-up time point who had response times < 15 min, which we considered highly unlikely (median completion duration = 29 min, IQR = 23-39.5; n = 7), were additionally excluded.
Psychiatric inpatients were recruited as part of the LMU Biobank study from the Department of Psychiatry and Psychotherapy of the LMU University Hospital Munich. Participants filled out the CoPaQ and other questionnaires (see below) using paper-pencil (n = 144). Exclusion criteria comprised an insufficient comprehension of German, an acute psychotic or manic episode, or acute suicidality. Furthermore, psychiatric inpatients' responses were excluded if they had more than 10% missing data on each of the self-report questionnaires (n = 31). Missing values were then imputed using the mis-sForest package [17] for non-parametric, iterative random-forest based imputation, which resulted in an imputation error of Out-of-bag PFC = 0.1748.
To ensure data integrity, careless responders (longest or average length of consecutive identical responses was ±3 SD of the respective sample mean) in the derivation sample (n = 27), longitudinal-(n = 5), and psychiatric validation samples (n = 0) were excluded from further analyses using the Careless package [18]. The final sample size of the derivation sample was n = 511, of the longitudinal validation sample n = 355, and of the psychiatric inpatient sample n = 113.

Other measures Depression, Anxiety and Stress Scales-21 (DASS-21)
The total score of the German version of DASS-21 [19,20] was included, which assesses psychological distress during the past week. Items are rated on a Likert scale of 0 (did not apply to me at all) to 3 (applied to me very much or most of the time). Higher scores indicate greater distress (range 0-63). In clinical and non-clinical samples good psychometric properties of the DASS-21 have been reported [21].

Revised-Green et al. Paranoid Thoughts Scale (R-GPTS)
Paranoid ideations over the past fortnight were assessed with the total score of the German version of the 18item R-GPTS [22,23]. Items are rated on a 5-point Likert scale ranging from 0 (not at all) to 4 (totally).
Higher scores indicate higher levels of paranoia (score range 0-72). Excellent psychometric properties of the scales have been reported for the English version [22].

WHO (Five) Well-Being Index (WHO-5)
Well-being over the past 2 weeks was assessed by the German version of the WHO-5 [24,25]. Items are rated on a 6-point Likert scale ranging from 0 (not present) to 5 (constantly present), with higher scores indicating greater well-being (score range: 0-30). Good psychometric properties have been reported in previous research [26].
Descriptive statistics and associations between variables were tested using bivariate Pearson's correlation coefficients, Chi-square tests (χ 2 ), and unpaired twosample t tests (Welch t-test) when appropriate. We report magnitudes of effect sizes of 0.10 considered "small", those of 0.30 as "medium", and those of 0.50 as "large" according to Cohen [28].
We conducted exploratory factor analysis (EFA) based on polychoric correlations with the maximum likelihood estimator (ML) and oblimin rotation to assess the structure of items and refine the item pool by deleting poorfitting items using the Psych package [29]. Items were then considered for deletion one at a time during EFA based on factor loadings (not loading higher than 0.30 on any factor, or loadings above 0.30 on more than one factor), communalities (<.30), content of items (e.g., theoretically inconsistent or redundant), item dependencies, sharp drop in item loading, and differences in response scale. In addition, items with an overall endorsement of < 10% across the derivation sample, longitudinal-and psychiatric validation samples were deleted. The number of factors to extract was determined through Empirical Kaiser Criterion (EKC), parallel analysis using polychoric correlations, and ML discrepancy function.
To validate the factor structure of the selected items per subscale, confirmatory factor analysis (CFA) with weighted least square mean and variance adjusted (WLSMV) estimator was conducted in the longitudinal and psychiatric validation samples using the lavaan package [30]. Model fit was assessed using the Comparative Fit Index (CFI; ≤.95 considered as acceptable) and Root Mean Square Error of Approximation (RMSEA; ≤ .08 considered as acceptable) following common recommendation [31]. Items, which loaded poorly on the factors in both validation samples, were deleted to arrive at the final version of the respective subscales of the questionnaire. Finally, we used modification indices to identify the best fitting model. Internal consistency of the different subscales with more than two items was determined by calculating McDonald's Omega (ω) and Cronbach's Alpha (α) using the MBESS package (v4.8.0; [32]).
Where appropriate, criterion and construct validity were established by testing differences (using Welch two sample t-tests) and strength of associations (using Pearson's r) in the derivation sample, respectively. To evaluate criterion validity of COVID-19 mental health impact subscales, we assessed if these subscales were associated with self-reported lifetime mental health diagnosis. In terms of construct validity, the COVID-19 mental health impact-, positive coping-, conspiracy-, and institutional & political trust subscale scores were correlated with different mental health outcome scores that related to psychological distress (DASS-21; [19]), psychological wellbeing (WHO-5;) [24], and paranoia (R-GPTS;) [22]).

Measures
Following validation of the CoPaQ, we selected the subscales inquiring about perceived countermeasure necessity and countermeasure compliance as well as COVID-19 contamination anxiety, COVID-19 institutional & political trust, COVID-19 conspiracy beliefs, and COVID-19 physical health risk factors for our research application example. We further included data on the DASS-21 anxiety subscale and refer to this as 'general anxiety' throughout the manuscript to demarcate this construct from 'COVID-19 contamination anxiety'. Finally, we assessed paranoia using the R-GPTS total score.

Assessment of group differences
We conducted Welch two sample t tests and calculated standardised mean differences (SMD) to assess group differences in support of COVID-19 related governmental restrictions and recommendations regarding perceived countermeasure necessity and countermeasure compliance as well as COVID-19 contamination anxiety, COVID-19 institutional & political trust, COVID-19 conspiracy beliefs, COVID-19 physical health risk factors, general anxiety, and paranoia. To assess robustness of results, also against violations of homoscedasticity, we provide 95% bootstrapped confidence intervals (95% CI) of the SMD values using 5000 bootstrapped samples with replacement. All hypothesis testing was two-tailed according to α = 0.05.

Correlation analysis
To explore the strength of statistical association between support of public health directives and COVID-19 contamination anxiety, COVID-19 institutional & political trust, COVID-19 conspiracy beliefs, COVID-19 physical health risk factors, general anxiety, and paranoia in clinical and non-clinical samples separately, we performed bivariate Spearman's rho (ρ) correlation analyses and tested whether the strength of associations differed between the clinical and non-clinical group by conducting Fisher Z transformations with adapted standard errors for Spearman's ρ [34].

Descriptive statistics
We provide participant characteristics of the derivation sample, longitudinal validation sample, and psychiatric validation sample in Table 1. The majority of the psychiatric inpatient sample had received a clinician's confirmed clinical diagnosis based on the International Statistical Classification of Diseases and Related Health Problems, 10th revision (ICD-10) criteria of depression, substance abuse disorder, personality disorder, and anxiety disorder. Comorbidity was high with more than two-third of patients meeting criteria for more than one psychiatric diagnosis (see Supplementary Table 1 for more details).

Exploratory and confirmatory factor analyses
Standardised oblimin rotated factor loadings of the final items are presented in Table 2. Model fit indices and internal consistency estimates of the respective subscales are presented in Tables 3 and 4, respectively. An overview of item selection decisions and related criteria for each subscale can be found in the Supplementary Material. Items loading on the respective subscales can be summed for further analyses.

Study populations characteristics
From the first section of the CoPaQ, which aims at characterising participant under study, we decided to omit the answer option "Don't know". We further removed optional questions relating to psychotherapy via telephone or video platforms from the final questionnaire version.

COVID-19 contamination anxiety
Following criteria of poor fitting items (see Methods section), we deleted two items due to redundancy with similarly worded items. The EKC and parallel analysis indicated a 2-factor solution. During EFA, three additional items were deleted due to low factor loadings, factor cross-loadings and only one item loading onto the second factor. Therefore, a 1-factor solution was tested in a next step and all items were retained in the final model. The factor entailed items related to COVID-19 contamination anxiety (e.g., "I am worried I will infect myself with COVID-19"). Subsequently, CFAs in the longitudinal-and psychiatric validation samples were conducted using the 1-factor 4-item model identified during EFA, which showed a good model fit.

COVID-19 necessity of and compliance with countermeasures
Theoretical considerations, the EKC, and parallel analysis favoured a 1-factor solution for each of the respective COVID-19 countermeasures. During EFA all items were retained. CFAs in the longitudinal-and psychiatric validation samples provided good to acceptable model fit for the respective COVID-19 hygiene measures-(e.g., "regular washing of hands"), social distancing-(e.g., "cancelling private meetings and family visits"), anxiety buying-(e.g., "soap, detergent, cleaning products, washing powder, etc."), political restrictions-(e.g., "temporary closure of bars, pubs, theatres, cinemas, etc."), and solidarity-based behaviours (e.g., "offering help to close friends and family members") subscales. The three items assessing COVID-19 countermeasure compliance of hygiene measures, social distancing, and curfews were grouped into an overall index since they were relatively independent from each other.

COVID-19 mental health impact
Poor fitting items were deleted due to poor content fit, dependency or redundancy. The EKC and parallel analysis indicated a three-factor solution. EFA suggested good model fit. Only one additional item was deleted due to high factor cross-loadings. Thereafter, all items were retained in the final model. The first factor entailed items related to COVID-19 post-traumatic stress disorder (PTSD) symptoms (e.g., "have had powerful images or memories that sometimes come into my mind in which I feel the experience of the COVID-19 pandemic is happening again in the here and now"), the second factor depicted COVID-19 sleep disturbance symptoms (e.g., "difficulty sleeping through the night"), and the third factor entailed items related to COVID-19 substance abuse (e.g., "have smoked considerably more cigarettes than usual"). Subsequently, CFAs in the longitudinal-and psychiatric validation samples were conducted using the 3-factor 13-item model identified during EFA, which did not provide a good model fit. Modification indices indicated dropping one additional poor fitting item, which was removed and the CFAs repeated. Now model fit indices suggested mixed results in the longitudinal validation sample with good to only adequate model fit according to RMSEA and CFI, respectively. Model fit in the psychiatric validation sample was good.

COVID-19-specific stressors impact
First, the not applicable answer option was recoded as zero and removed from in the final validated questionnaire version. Items with poorly fitting content were then deleted. In addition, items related to the ability to distance oneself from the stressors were deleted due to item dependency. As each stressor (e.g., "childcare", "being in quarantine" or "being in home office") can occur relatively independently, no factor analysis was applied for COVID-19-specific stressors, so the remaining items can be summed to an index.

COVID-19 positive coping
Three items were deleted due to poor item-scale content fit. The EKC and parallel analysis indicated a threefactor solution, which we evaluated in the subsequent EFA. During EFA, one additional item was deleted due   to low factor loadings. The first factor entailed items related to keeping a daytime structure (e.g., "have planned the day as detailed as possible"), the second factor depicted positive coping items in terms of social contacts (e.g., "have maintained my social contacts (telephone, visits or video chats)"), and the third factor entailed items related to inner strength (e.g., "have changed my attitudes about what is really important to me in life") during the pandemic. Subsequently, CFAs in the longitudinal-and psychiatric validation samples were conducted using the 3-factor 9-item model identified during EFA, which resulted in a poor model fit. Two additional items from the social contacts and inner strength subscales were deleted due to poor model and content fit. The subsequent model fit was good across samples.

COVID-19 institutional & political trust
First, we deleted one item due to item content. One item was reversed coded. The EKC and parallel analysis indicated a one-factor solution. During EFA all items were retained and related to political and institutional trust (e.g., "have had the feeling that the political leadership was standing up for me"). Subsequently, CFAs in the validation samples were conducted using the 1-factor 5item model identified during EFA, which provided a poor model fit in the longitudinal validation sample and good model fit in the psychiatric validation sample.

COVID-19 conspiracy beliefs
We deleted one item due to a different response format. The EKC and parallel analysis indicated a 1-factor solution. During EFA all items were retained. The factor entailed items related to COVID-19 conspiracy beliefs (e.g., "have had the belief that what is happening here is the effect of a struggle or competition between different superpowers"). Subsequently, CFAs in our validation samples were conducted using the 1-factor 5-item model identified during EFA, which provided an acceptable model fit in the longitudinal but not in the psychiatric validation sample.

COVID-19 social cohesion
First, three items were removed due to item redundancy. The EKC and parallel analysis indicated a one-factor solution. During EFA all items were retained and related  to COVID-19 social cohesion (e.g., "our nation is growing closer together"). Subsequently, CFAs in our validation samples were conducted using the 1-factor 3-item model identified during EFA, which provided a good model fit in the longitudinal sample, but resulted in model misspecification in the psychiatric validation sample.

Omitted subscales
The theoretically constructed subscales of COVID-19 media use (e.g., "have carried out an increased amount of research about the COVID-19 pandemic via the Internet"), COVID-19 interpersonal conflicts (e.g., "have had more physical arguments (e.g. beating, boxing, kicking) with people close to me"), and COVID-19 paranoid ideations (e.g., "have had the belief that the corona-virus was introduced to get at people like me") were omitted from the CoPaQ measure due to poor model fit during EFA.

Internal consistency
Overall, the CoPaQ subscale factors' internal consistency estimates ranged from acceptable to excellent in our derivation-, longitudinal-and psychiatric samples.

Construct and criterion validity
The COVID-19-specific stressor and mental health impact subscales were associated with all mental health outcomes and most strongly with greater psychological distress; the COVID-19 positive coping subscales were most strongly associated with greater psychological wellbeing; and the COVID-19 institutional & political trust and COVID-19 conspiracy beliefs subscales were most strongly associated with lower and higher paranoia levels, respectively (see Table 5). Table 6 shows the results for the evaluation of criterion validity, which shows that the COVID-19 mental health impact subscales were more strongly endorsed if the participant had selfreported a lifetime mental health diagnosis.  Further, COVID-19 contamination anxiety, COVID-19 institutional & political trust, and COVID-19 conspiracy beliefs did not differ between groups, whereas psychiatric inpatients indicated higher levels of general anxiety and COVID-19 physical health risk factors compared to non-clinical individuals with medium to high effect sizes (see Table 7).
Necessity and compliance of COVID-19 public health countermeasure were positively associated with COVID-19 contamination anxiety and COVID-19 institutional & political trust in the clinical (Spearman's ρ coefficients ranged from .19 to .36) and non-clinical group (Spearman's ρ coefficients ranged from .36 to .64). Here, the strengths of associations were observed to be stronger in In the non-clinical sample only, COVID-19 conspiracy beliefs were negatively associated with COVID-19 countermeasure necessity and compliance (absolute ρ coefficients ranged from 0.30 to 0.40). Fisher's Z tests indicated that these associations were significantly stronger in the non-clinical than clinical group for the perception of necessity of social distancing (Z = 2.33, p = 0.02) and political restrictions (Z = 2.36, p = 0.02) but not for hygiene measures (Z = 1.72, p = 0.08) or overall compliance (Z = 1.21, p = 0.23). In

Discussion
Understanding the psychosocial impact of the COVID-19 pandemic in different study populations has become an international priority. In this study, we report first findings from the assessment of psychiatric inpatients and non-clinical subjects using the CoPaQ tool that was designed to measure key psychosocial aspects of the pandemic including contamination anxiety, countermeasure necessity and compliance, mental health impact, COVID-19-specific stressor impact, social media usage, interpersonal conflicts, paranoid ideations, institutional & political trust, conspiracy beliefs, and social cohesion. The questionnaire was developed for application in different study populations, has been published on the Open Science Framework and is currently available in 11 languages. Here, we conducted a psychometric evaluation of the scale in its German version using data from a longitudinal sample of non-clinical individuals and psychiatric inpatients. Factor analyses indicated that 12 out of 16 extracted subscales showed acceptable to good model fit indices, internal consistency estimates and, where appropriate, construct and criterion validity in at least one validation sample. Therefore, these subscales were retained in the final version of the CoPaQ. Overall, the final version of the CoPaQ represents a valid measure that can help to better understand key aspects affected by the pandemic as illustrated by our research application example. Psychometric validation in the longitudinal nonclinical and psychiatric validation samples demonstrated key strengths and limitations of individual CoPaQ subscales. The theoretically constructed 'COVID-19 social  In order to present a first use case for which new tools are required for addressing a research question specific for the COVID-19 pandemic, we investigated whether psychiatric inpatients may have lower compliance with preventive countermeasures as previously discussed by some authors [5,6]. Contrary to this view, our results indicate that the support of public health directives to contain the spread of the coronavirus was indeed greater in psychiatric inpatients primarily admitted for major depressive-, substance abuse-, personality-, and anxiety disorders, compared to age-, sex-, and employment status matched non-clinical individuals. Results may be regarded as preliminary evidence against the hypothesis that higher SARS-Cov-2 infection rates in psychiatric patients are due to lower adherence to countermeasures [5,6]. Findings from correlational analyses indicated that particularly trust in institutions & politics as well as contamination anxiety were associated with increased levels of support of public health directives during the pandemic in clinical-and non-clinical individuals, which is in line with previous research [7][8][9][10]. However, general anxiety was additionally associated with increased support of public health directives only in the clinical sample. This could indicate general anxiety is a putative driver of the increased reported support of countermeasures in psychiatric patients, that we observed in our sample. It is important to note, however, that these results are restricted by non-significant correlational differences between samples. Additionally, the psychiatric inpatient setting may explain part of our findings since non-acceptance and non-compliance may likely lead to hospital discharge, social pressure from hospital staff and fellow patients, and a greater uncontrollable risk of infection in a relatively crowded hospital environment. In addition, paper-pencil questionnaire completion in the psychiatric patient sample may have contributed to greater socially desirable responses compared to online completion in the non-clinical group. Moreover, our findings and conclusions may not be extended to other diagnoses (e.g., a sample consisting of patients with psychotic disorders only) or treatment settings (e.g., outpatients).

Limitations
There are obvious methodological limitations of our study: First, we have assessed construct validity and criterion validity for some but not all subscales of the CoPaQ. Future studies should test whether the other subscales assess what they are intended to measure. Second, since we applied the German version of the CoPaQ, generalisability of results to other languages/cultures is limited, which needs to be addressed in future research. Wider distribution of the CoPaQ and its translated versions in our open science approach would leverage such transcultural studies. Third, CFAs were based on relatively small sample sizes, which may have affected the robustness of results. As such, replications in larger study cohorts are needed. Fourth, the clinical and nonclinical samples are unlikely to fully represent the populations from which they were drawn. Finally, research needs to assess the CoPaQ's predictive validity, testretest reliability, and conduct evaluations in other study populations.

Conclusion
Notwithstanding these caveats, the CoPaQ is a comprehensive, yet relatively brief self-assessment tool that covers a broad spectrum of pressing psychosocial topics during the current COVID-19 pandemic. The scale has the potential to facilitate the investigation of psychosocial reactions to the pandemic and could help assess the impact of potential future epidemics and pandemics if adapted accordingly. Our use case highlights its potential to untangle complex psychosocial aspects regarding levels of support of COVID-19 countermeasures in psychiatric inpatients and non-clinical individuals. Our findings stress the importance of transparent public health communication to foster trust in institutions and politics as well as inform the public about the potential contagiousness of the coronavirus to increase acceptance and adherence with the different public health directives in clinical and non-clinical groups during the current pandemic.