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The Impact of Elevated Progesterone on the Initiation of an Artificially Prepared Frozen Embryo Transfer Cycle: A Case Series.

BACKGROUND
The role of elevated baseline progesterone (P) levels in outcomes of frozen embryo transfers (FET) performed in an artificial cycle has not been investigated yet.


OBJECTIVE
To evaluate the role of elevated P in artificial FET.


METHOD
Case series study of 12 patients with high P levels undergoing artificial FET recruited during a 6-month period in a tertiary referral center.


RESULTS
The clinical pregnancy rate per transfer was 4/12 (33.3%). The biochemical pregnancy rate was 6/12 (50.0%).


CONCLUSION
Elevated levels of P do not seem to have a negative impact on reproductive outcome, and may even be associated with high clinical and biochemical pregnancy rates. Further prospective or large retrospective studies are required to examine the clinical importance of our findings in a larger population.