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Classification of Subcellular Protein Patterns in Human Cells with Transfer Learning

In this paper, we present a deep learning method for classifying subcellular protein patterns in human cells. Our method is mainly based on transfer learning and utilizes a newly proposed loss function named focal loss to deal with the problem of severe class imbalance existing in the task. The performance of our method is evaluated by a MacroF1 score of total 28 classes, and the final MacroF1 score of our method is 0.706.