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Health-related quality of life in postrenal transplant patients: A single-center study

Background: The study was conducted to look for association of health-related quality of life (HRQoL) with renal functions in renal transplant recipients and to examine which clinical measures after renal transplantation are connected to aspects of their HRQoL. Materials and Methods: The study was carried out at IKDRC/ITS, Ahmedabad, between 2013 and 2016. Only patients who completed minimum 3 months posttransplant were included in the study. The responses were summarized and transformed to give eight summary scales which were grouped as physical component summary (PCS) and mental component summary (MCS) to give total HRQoL. Results: Out of 54 patients, 74% were males and 26% patients were females. Age distribution was between 18 and 62 years. Most common cause of end-stage renal disease was chronic glomerulonephritis (42.6%). Forty-seven patients underwent live-related kidney transplant while 7 received kidneys from cadaver. Mental health and MCS scores in males were significantly higher (<0.05) than females. With respect to age, the transplant patients were divided into four groups: younger than 30 years, 30–39 years, 40–49 years, and 50-year-old or older. No difference was found in any scale score between the age groups. The scale scores of PCS in patients with serum creatinine level >2 mg/dL were significantly lower (<0.05) than those of patients with serum creatinine <2 mg/dl. When compared in between patients who had rejection to those who did not, there was no significant difference in MCS and PCS. The scores of patients with cadaveric transplantation were similar to those who received a living-related transplantation. Longer time since the transplant operation was significantly associated with lower scores of the vitality scale. Conclusion: SF-36 V2 is a good tool to monitor HRQoL in renal transplant recipients. Episodes of hospitalization and rejection did not affect the present HRQoL in our study.