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The Varying Behavior of Stent Thrombosis in Native Coronary Arteries Versus Aorto-Coronary Saphenous Vein Bypass Grafts.

Out-of-lab closure due to stent thrombosis is a major limitation of stent implantation. In this report, the incidence of stent thrombosis in native coronary arteries is compared to saphenous vein bypass grafts. Elective stent placement was performed in 1,782 patients. Overall, stent thrombosis occurred in 64 (3.6%) of patients. There was a significantly higher incidence of stent thrombosis in native coronary arteries (56/1153, 4.9%) compared with venous bypass grafts (8/629, 1.3%), (p < 0.0001). Multivariate analysis demonstrated vessel size to be the most important predictor of stent thrombosis. We conclude that stent thrombosis occurs less frequently in vein bypass grafts and that the risk in the native circulation is inversely related to vessel size.