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OP26.10: Assessment of fetal cardiac function and structure in monochorionic diamniotic twins with Twin–twin transfusion syndrome before and after fetal therapy

NT-proBNP/TP was elevated (3,475 vs. 518 ng/g, p=0.008), and ductus venosus pulsatility index (DV-PI) was high (1.34 vs. 0.75, p=0.020). Bilateral E/e’ in recipients decreased 4-7 days after FLP (p=0.007). As for donor twins, no significant change was seen in bilateral E/e’. Conclusions: The measurement of fetal E/e’ using DD method was convenient and stable. E/e’ is seemed a useful parameter of fetal cardiac dysfunction in recipient twins, related with amniotic fluid NT-proBNP and DV-PI. Interestingly, bilateral E/e’ of recipients indicated significant decrease within 7 days after FLP. These findings might imply FLP improves pathological condition of diastolic dysfunction in recipient twins.