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62 Hypertension as a Risk Factor for Cognitive Decline in The Elderly With Obesity

Introduction: Obesity is an important predisposing factor for vascular diseases and cognitive impairment. The aim of this study is to learn about the role of hypertension in cognitive impairment among elderly with obesity. Methods: A cross-sectional study involving 244 subjects with obesity. Participants were already recruited from Active Ageing Research (Atma Jaya Medical School) from 2011–2015. Cognitive functions are evaluated using MMSE, WLMIR, Boston Naming Test and Verbal Fluency Test. Anthropometric measures are collected to obtain Body Mass Index (BMI); obesity is defined by cut off value ≥ 25. Results: The mean age is 64.95 ± 7.06 years old and most subjects are women (77.5%). Bivariate analysis significantly shows that the level of education is related with cognitive decline (MMSE, WLMIR, BNT, VFT) (p < 0.05; OR: 14.3;2.25;4.29;2.91). Other variables (gender, hypertension, HDL level) are also significantly related with cognitive decline only in certain domains (MMSE, BNT, VFT) (P < 0.05). In this study, low level of education and hypertension are the two variables identified being the risk factors for low MMSE & VFT scores in the elderly with obesity using multivariate analysis. Conclusion: Hypertension and low level of education are the risk factors for cognitive decline in obese elderly.