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Enantioselective recognition in biomimetic single artificial nanochannels.

Efficient enantiomer discrimination with a convenient system remains a challenge in the fields of biochemistry, medical science, and pharmaceutics. Here we report a simple enantioselective sensing device based on a single artificial β-cyclodextrin-modified nanochannel system. This nanodevice shows highly selective recognition of histidine enantiomers through monitoring of ionic current signatures.