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Analytical applications of near-infrared fluorescent probes

By combining near-infrared (NIR) fluorophores and commercially available laser diodes, a promising technique emerges where visible probes are less effective due to background interference. The application of NIR fluorophores in fiber-optic probes for the determination of metal ions in the environment and for biological assays will be discussed. The spectral behavior of a new NIR fluorophore TG-170 in the presence of metal ions and the first synthesis and spectral characterization of a NIR dye KVA-22 substituted with a crown ether, a metal complexing functionality, will be presented.