{'fraction_non_alphanumeric': 0.028598665395614873, 'fraction_numerical': 0.03908484270734033, 'mean_word_length': 5.0, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
EVALUATION OF ANTIOXIDANT, ANALGESIC AND ANTI-INFLAMMATORY PROPERTIES OF SEDUM ADENOTRICHUM

Sedum adenotrichum crude extract have been evaluated for in vitro antioxidant activities and in vivo analgesic and anti-inflammatory potentials. Results showed strong ABTS, H2O2, and DPPH free radical scavenging activities. The extract caused a significant decline of acetic acid-induced abdominal constrictions whereas, significantly inhibited both phases of formalin-induced paw licking responses. In tail immersion assay a significant analgesic response of 58.65% was observed at 75 min at a dose of 125 mg and 60.67% at 90 min at a dose of 250 mg. The morphine exhibited dominant activity at 60 min after treatment of 84.86%. Animals treated with naloxone produced a significant reduction in analgesic potentials of morphine and extract. In the carrageenan-induced model for anti-inflammatory activity, edema formation was inhibited by the extract in the 3 hour at a dose of 100 and 200 mg, by 50.75 and 52.49%, respectively in a dose-dependent manner.