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Serum calcitonin in patients with osteolytic and osteosclerotic metastases from mammary carcinoma.

Serum concentrations of calcitonin, calcium, phosphorus and alkaline phosphatase were measured in 19 patients with osteolytic metastases and in 8 patients with osteosclerotic metastases from mammary carcinoma. A significantly higher mean S-iCT concentration was found in patients with osteolytic metastases as compared with those with osteosclerotic. No significant difference was found in S-calcium, S-phosphorus or S-alkaline phosphatase between the two groups.