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Constructing Phylogenetic Tree Based on Three-Parameter Model

Neighbor Joining Algorithm (Neighbor-Joining or NJ) is a common way to construct phylogenetic trees. To enhance the accuracy of constructing the phylogenetic trees, we use the Kimura three-parameter model to calculate the distance between sequences, raising a way to improve NJ. By computer simulation, we made a comparative analysis of the accuracy among the improved NJ, UPGMA, and the original NJ, the result showing that the improved NJ is superior to UPGMA and the original NJ.