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Extended spectrum β-Lactamases producing Klebsiella pneumoniae: A threat to patient care

Background and Objectives: Extended spectrum β-lactamases (ESBL) producing Klebsiella pneumoniae strains are increasing worldwide and pose a major threat to patient care. Hence, the present study was undertaken to detect the incidence of ESBL producing K. pneumoniae strains isolated from different clinical specimens in the Department of Microbiology. Study Design: The study was approved by Institutional Ethical Committee. The type of study was cross sectional observational study. 120 K. pneumoniae strains were studied. Antibiotic susceptibility test was done by Kirby-Bauer disc diffusion method. ESBL production was detected phenotypically by confirmatory test e.g. combined disc method. Results: Out of 120 K. pneumoniae strains, 55 (45.8%) strains were ESBL producers. All 100% strains were sensitive to Colistin. Conclusion: Hence, to conclude, all K. pneumoniae strains, isolated in Clinical Microbiology Laboratory should be tested phenotypically for ESBL production.