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Hospital mortality and Leapfrog Hospital Survey results.

previous ketoacidosis and not using steroids is shown in the FIGURE. The dashed lines indicate the 95% confidence interval, which becomes extremely wide at the right end due to the low numbers of patients at risk at later follow-up (TABLE). Because of this, results of actuarial survival data are often presented as percentage response at the middle of the follow-up period (approximately 70% including 20 patients, and 60% including 23 patients), not at the maximum follow-up time. As described in our preliminary communication, the study protocol was modified after experience with the first enrolled patient to exclude patients with previous diabetic ketoacidosis or those who had received corticosteroids pretransplant. Because 3 patients did not fulfill the modified protocol criteria, we think that it is appropriate to have excluded them from the analysis. We also note that C-peptide level, not insulin independence, is the primary end point of the study; C-peptide levels increased even in patients who resumed insulin use.