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Bactericidal activity of preservative‐free bupivacaine on microorganisms in the human skin flora

Background: The rate at which the bactericidal activity of preservative‐free bupivacaine develops at body temperature and at room temperature is not known. We studied the bactericidal activity of preservative‐free bupivacaine on two strains of methicillin‐resistant Staphylococcus aureus (MRSA), two strains of methicillin‐susceptible S. aureus (MSSA), and each of Staphylococcus epidermidis and Escherichia coli.