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NAFLD in clinical practice: Can simple blood and anthropometric markers be used to detect change in liver fat measured by 1H‐MRS?

Research in NAFLD management is commonly based on quantitative assessment of liver fat by proton‐magnetic resonance spectroscopy (1H‐MRS), and translation of this into clinical practice is currently limited by availability and expense. Novel steatosis biomarkers have been proposed for the prediction of liver fatness; however, whether these are suitable for detecting changes in liver fat is unknown. We aimed to determine the accuracy of these indices, and waist circumference (WC), in quantifying longitudinal change in 1H‐MRS‐quantified liver fat.