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Vascular endothelial growth factor concentrations in serum of patients with extensive slow‐flow vascular malformations

pausal age with all the typical features of FFA. FFA is considered a variety of lichen planopilaris, which selectively involves the hairline. The occurrence of familial cases of lichen planus is well known and the occurrence of Lassueur– Graham-Little–Piccardi syndrome (LGLPS) in a mother and her daughter was reported in 2004. LGLPS is considered a variant of lichen planopilaris because of their similar clinical and histopathological features. In addition HLA-DR1 was found in the two familial cases of LGLPS reported, as in the genetic studies on HLA typing in familial lichen planus. Whereas there is an increasing number of reported cases of FFA in the literature, this is the first familial report of the disease. The selective involvement of the frontotemporal hairline that characterizes FFA is not explained, and the aetiology of the disease is still obscure. Our cases suggest that familial or genetic factors may also contribute to the development of FFA.