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Re: Relationship between Cannabis Use and Erectile Dysfunction: A Systematic Review and Meta-Analysis.

available at http://www.ncbi.nlm.nih.gov/pubmed/31795801 Editorial Comment: The aim of this study was to summarize the prevalence and risk of erectile dysfunction (ED) in cannabis users compared to controls. The authors systematically reviewed major databases from study inception to January 1, 2019, without language restriction, to identify series investigating cannabis use and presence of ED. Overall prevalence of ED was 69.1% (95% CI 38.089.1) in cannabis users and 34.7% (95% CI 20.3-52.7) in controls. Odds ratio of ED in cannabis users was almost 4 times that of controls (OR 3.83, 95% CI 1.30-11.28, p[0.02). The data suggest that the ED rate is twice as high in cannabis users as in controls. Very important information.