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[Pathophysiological aspects of heart failure complicating the course of myocardial infarct].

An analysis is presented of the central hemodynamics records obtained by catheterization of the cardiac chambers and echocardiography in 74 patients with acute myocardial infarction (AMI). Administration of vasodilators and anticalcium agents is recommended during first 6 hours of AMI; later, in the presence of clinical symptoms of heart failure, cardiac glycosides should be added. The authors claim that nitroglycerin is a vasodilator and cardiotonic agent whose inotropic effect is mediated through the diastolic phase by eliminating the myocardial contracture during the first hours of AMI.