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A Remarkably Useless New Name in Rheumatology

The cremains from the Chieftain’s grave are the only human remains available from this type of “princely burial” in The Netherlands. The estimated age of the individual in this grave was 30–40 years, based on osteologic and histologic age assessment (4,5), and signs of DISH were clearly apparent (6). In the study by Saleem and Hawass, 3 of the pharaohs in which the findings in their mummies fulfilled the diagnostic criteria for DISH were relatively young (ages 50, 55, and 60 years, respectively). It should be taken into account that, as in the Chieftain, the first manifestations of DISH in these pharaohs had developed at an even younger age. In modern populations, DISH is often a chance discovery and coexists with osteoarthritis (OA) (2). In contrast, OA was nearly absent in 3 of the pharaohs and in the Chieftain. Thus, there is support for the notion that DISH manifested at a later age over the milennia, and that coexistence of DISH with OA became more prevalent in the modern-era population. Therefore, it seems likely that the phenotype of DISH has changed over the centuries.