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Iodine-Catalyzed Synthesis of Highly Functionalized 1,4-Dihydropyridines from 2-Aminobenzothiazole, Aryl Aldehydes and Meldrum’s Acid via Diels-Alder [4 + 2] Cycloaddition Reaction

Abstract An efficient and simple method for the synthesis of novel highly functionalized 1,4-dihydropyridines via a one-pot three-component reaction of 2-aminobenzothiazole, aryl aldehydes and Meldrum’s acid in the presence of iodine is reported. All the products were obtained in good yields and their structures were established from their spectroscopic data.