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[Effect of dietary fat load on the gas exchange parameters and physical work capacity in healthy people and patients with ischemic heart disease].

The impact of alimentary fat load on physical fitness and gas exchange parameters was studied in 20 healthy individuals and 20 patients with preclinical coronary heart disease (CHD) and 16 patients with manifest CHD. The healthy persons and the patients with preclinical CHD were found to have higher maximum oxygen consumption, increased metabolic units and oxygen pulse during maximum exercises in the presence of fat load, as compared to the values obtained in the exercise test without fat load. In patients with manifest CHD who had alimentary fat load, their physical working capacity decreased: myocardial ischemia developed more rapidly if the test was performed after meal; they also showed lower maximum oxygen consumption, decreased metabolic units and oxygen pulse after fat load tests. The application of spirobicycle ergometry and dietary fat intake enabled a group of persons with patent CHD to be clearly differentiated from that of healthy individuals and patients with evident clinical signs of CHD as compared to the use of spirobycicle without fat load.