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Influence of lipid and leukocytes on the haemoglobin determination by Coulter Counter S Plus III, Technicon H 6000, Technicon H 1, LK 540, Reflotron and Hemocap.

The influence of lipid and high concentrations of leukocytes on the haemoglobin determination by six different instruments was examined. The increase in the determination of haemoglobin concentration with elevated amounts of lipid in the samples was greatest with the Coulter Counter S plus III and the Technicon H 1 followed by the LK 540 and the Technicon H 6000. There was no effect of lipid on the haemoglobin determination using the Reflotron. High concentrations of leukocytes increased the haemoglobin determination most by Coulter Counter S plus III and Hemocap. There were no changes in the haemoglobin determinations by the LK 540 and the Technicon H 6000 when the samples contained increased amounts of leukocytes.