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OR73. The Relationship Between Echocardiographic Parameters and Chronotropic Incompetence in Patients with Cardiovascular Disease at Sanglah General Hospital, Bali


 
 
 Patients with cardiovascular disease commonly have chronotropic incompetence which may be associated with cardiac remodelling and increased LV filling pressure. This study aimed to determine the association between echocardiography findings and chronotropic incompetence (CI) among patients with cardiovascular disease.
 
 
 
 This was a cross-sectional study that included 136 medical records of patients with cardiovascular disease underwent treadmill stress test (TST) and echocardiography examination at outpatient cardiology clinic, Sanglah General Hospital from 2018 until 2020. Chronotropic incompetence was defined as maximum heart rate that can’t reach 85% age-predicted maximum heart rate. Data was analyzed using SPSS version 21. Mann-Whitney U test was used to evaluate the association between echocardiography findings such as ejection fraction (EF), left ventricular internal dimension end-diastolic (LVIDd), LVIDd index (LVIDdi), left ventricular mass, E/E’ ratio, left atrial volume index (LAVI) and CI. Among 136 subjects of this study, the mean age was 54.7 years, 71.3% were male and 37.5% were obese. Patients with CI were found to had lower LVIDd (42.8+0.89 vs 45.2+0.72, p = 0.029), lower LVIDi (24.6+0.37 vs 25.5+ 0.31, p = 0.025), higher left ventricular mass (175.6+3.27 vs 125.1+2.63, p < 0.001), higher E/E’ ratio (17.3+0.29 vs 13+0.35, p < 0.001), and higher LAVI (47+1.98 vs 31.6+1.09, p < 0.001) compared with patients without CI.
 
 
 
 Patients with cardiovascular disease commonly have chronotropic incompetence that could be detected by TST examination, which may be partly predicted by echocardiographic parameters that are associated with cardiac remodelling and increased LV filling pressure.
