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A systematic review of health state utility values in Thai cancer patients

ABSTRACT Introduction Health state utility value (HSUV) is an important outcome of cost-utility analysis. The EQ-5D is commonly used to elicit the HSUV of economic analyses based on the recommendations of the Thai health technology assessment guideline. Therefore, this study aimed to establish a dataset of utility values in patients with liver, lung, colorectal, breast, and cervical cancers at different stages in Thailand. Areas covered In total, 25 studies were identified from PubMed, Scopus, Thai Library Integrated System, Health Intervention and Technology Assessment Program, and Health System Research Institute from inception to May 2021. The EQ-5D 3 Level Version was commonly used to identify the HSUVs of Thai patients with cancer. Meanwhile, the use of the EQ-5D 5 Level Version was supported by psychometric testing. However, mapping techniques between disease-specific and health preference-based instruments was utilized. Expert opinion This study showed that patients with colorectal cancer had the highest HSUVs for both the earlier and metastatic stages. Additionally, the differences in HSUVs were found among studies because of the different chemotherapy treatments and elicitation methods. Therefore, it is generally recommended that health economists use HSUVs derived from using the same method for an economic evaluation.