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Staphylococcal‐derived superantigen enhances peanut induced Th2 responses in the skin

The allergen‐induced activation and expansion of IL‐4 producing T helper type 2 (Th2) cells is a key event in the initiation and progression of allergic disease. Intriguingly, concomitant early childhood staphylococcal skin infections are being increasingly implicated in the allergen‐induced switch of primary T cell responses towards the Th2 phenotype.