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PD06-10 PREDICTORS OF URINARY INCONTINENCE AMONG HISPANIC/LATINA WOMEN IN THE UNITED STATES: FINDINGS FROM THE HISPANIC COMMUNITY HEALTH STUDY/STUDY OF LATINOS (HCHS/SOL)

LUTS over 12 months. METHODS: Adult women seeking care for LUTS were enrolled in the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) observational cohort study. Urinary symptoms were assessed using the LUTS Tool and PFDI at baseline, 3, and 12 months. LUTS Tool items representing common symptom domains were combined using weighted Euclidian length. Physical functioning, depression, and sleep disturbance were measured using PROMIS questionnaires, and relationships were assessed using multivariable linear mixed effects regression models adjusted for clinical variables. RESULTS: Of 545 women enrolled in LURN, 472 had follow-up at 3 and/or 12 months and were included in this analysis. Median age was 57 years, 83% were White, and 47% were obese. PROMIS depression scores were positively associated with all urinary outcomes (range 2.5-4.8 unit increase per 10 unit increase in depression score, p < 0.01, Figure). Higher sleep disturbance scores were associated with higher urgency, obstructive, and total LUTS severity scores as well as UDI and total PFDI (1.9-3.6 point increase in urinary symptoms per 10-unit increase, all p < 0.02), but not SUI severity, POPDI or CRADI scores. Higher PROMIS physical functioning scores were associated with lower scores on all urinary symptom measures except SUI (2.3-5.2 point decrease per 10-unit increase, all p < 0.01). Higher BMI and current or former smoking status were associated with higher SUI severity scores, while older age was associated with lower UDI and POPDI scores. All symptom scores were lower at 3 and 12 months compared to baseline. CONCLUSIONS: Physical and psychological factors demon-strated mild to moderate associations with urinary symptom domains. INTRODUCTION AND OBJECTIVE: Studies show racial dif- ferences in prevalence of stress urinary incontinence (SUI), urge urinary incontinence (UUI), and mixed urinary incontinence (MUI). While medical conditions may vary by Hispanic/Latina backgrounds, differences in urinary incontinence (UI) and UI subtypes are not described. We aim to identify predictors of UI in women of various Hispanic/Latina backgrounds. METHODS: The HCHS/SOL is a multicenter (Bronx, Chicago, Miami, and San Diego), prospective cohort study which includes health-related questionnaires of men and women 18-74 years of age. The Visit 2 Medical Health questionnaire included questions on presence and type of UI. Multiple logistic regression analysis was used to compute odds ratios (OR) and 95% con ﬁ dence intervals [CI]. We adjusted for age, BMI, smoking and alcohol usage, and socioeconomic factors (education, employment, annual household income, and nativity (time spent living in the 50 US states or DC)). All estimates were weighted and accounted for HCHS/SOL survey design. RESULTS: