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SFRP5 correlates with obesity and metabolic syndrome and increases after weight loss in children

Secreted frizzled‐related protein 5 (SFRP5) is a novel anti‐inflammatory adipokine, which has been shown as a mediator between obesity and its comorbidities. The aim of this study was to evaluate the associations of SFRP5 with metabolic syndrome (MetS) and the effects of lifestyle interventions on circulating SFRP5 levels in children.