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Supplementation with Embryo Chicken Egg Extract Improves Exercise Performance and Exerts Anti-Fatigue Effects via AMPK/ mTOR Signalling Pathway in Mice.

BACKGROUND
Embryo Chicken Egg is a nutritional supplement used to enhance physical fitness and promote wound healing according to the traditional Chinese medicine for many years. In this study, we evaluated the effects of Embryo Chicken Egg extract (ECE) on the exercise performance and fatigue in mice and the underlying mechanisms.


RESULTS
The results indicated that ECE can prolong the exhaustive swimming time, decrease Lactic Acid (LA), Blood Urea Nitrogen (BUN), Creatine Kinase (CK) and Malondialdehyde (MDA) levels, and increase Superoxide Dismutase (SOD), Glutathione Peroxidase (GSH-Px) and glycogen levels. Addition, ECE can also regulate the balance of oxidative stress via AMPK/ mTOR signaling pathway.


CONCLUSION
Taking together, these results showed that ECE can improve exercise performance and reduce physical fatigue in mice, which indicates that ECE can be used as a potential supplement to reduce physical fatigue. This article is protected by copyright. All rights reserved.