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[Effect of alpha-tocopherol and synthetic antioxidants on morpho-functional status of gonadotropic cells from the adenohypophysis of albino rats].

Morphometric indices of gonadotropic cells obtained from adenohypophysis of white rats, both males and females, were investigated after treatment with alpha-tocopherol and synthetic antioxidants. The former stimulated the functional status of gonadotropic cells revealed in a proportional increase in both nuclear and cytoplasmic volumes. After the treatment with a synthetic antioxidant dibunolum, the volume of the cytoplasm increased in gonadotropic cells of rats of different sexes. After the treatment with a water-soluble antioxidant emoxipinum, the volume of the cytoplasm in gonadotropic cells increased only in males. The outcomes allow to consider alpha-tocopherol, in contrast to from synthetic antioxidants, as one of the modulators of the functional state of gonadotropic cells obtained from adenohypophysis.