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Multicentre trials on specialised exercise training and rehabilitation are useful in patients with pulmonary hypertension

We would like to thank L. Bertoletti and co-workers for their important comments. We fully agree that more multicentre data, especially on the haemodynamic effects of rehabilitation programmes, are needed and might be helpful for re-evaluating the current level of evidence and indication of exercise training in pulmonary hypertension. A new grading of evidence and recommendation of treatment was not the purpose of the task force statement and hence not alluded to. This has to be done through authorised committees. We also agree with L. Bertoletti and co-workers' excellent description of the methodological difficulties of measuring the efficacy and long-term outcome of exercise training in pulmonary hypertension. Therefore, the new initiative for a prospective, randomised trial using new methods for randomisation is highly welcomed and should be supported. Multicentre trials on specialised exercise training and rehabilitation in patients with pulmonary hypertension are needed to provide further evidence on its haemodynamic effects and to show implementation in different healthcare systems is possible. http://bit.ly/2L4Mrgt