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The Mechanism of Graft Rejection and the Concept of Antigenic Strength

‘It must be for almost ten years now that I have been stubbornly holding the view that the strength of transplantation antigens is essentially a direct function of the number of immunologically competent (antigen sensitive) cells which can recognize the antigen as foreign and react against it’. (Morten Simonsen, 1970 [13].)