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Chance favours the prepared mind.

In 1808 Robert Willan described psoriasis as a clinical entity in his book “ On Cutaneous Diseases(1). Most new treatments for psoriasis for more than 100 years have been discovered through serendipity and not through scientific design. We contest that the art of medicine is the prime innovator for radical new therapeutic approaches, whereas the science of medicine is responsible for slow incremental change.