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The Relationship Between Congenital Defects and the Use of Exogenous Progestational “Contraceptive” Hormones During Pregnancy: A 20‐Year Review

This review of 20 years of medical literature on the occurrence of congenital defects among offspring of women who ingested “progestational” or contraceptive hormones during pregnancy emphasizes the need for additional studies with carefully selected control groups. Other problems encountered in interpreting the existing literature, including the use of imprecise definitions, confusing nomenclature and inadequate clinical information, are also discussed.