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[Thromboembolism risk factors in kidney transplant patients with secondary erythrocytosis in relation to hemorheologic aspects].

In patients undergoing dialysis and patients who underwent a transplantation of a kidney cardiovascular risk factors increase the lethality to 50%. A secondary polyglobulia (Pg) after transplantation enhances the risks of thromboembolism. In 180 patients who underwent a transplantation we saw in 11% a polyglobulia with 50% of thromboembolic complications. For the study of the secondary polyglobulia and other risk factors haemorheologic investigations were carried out on 20 patients who underwent a transplantation with Pg, 10 patients who underwent a transplantation without Pg and 19 healthy test persons. In patients with secondary polyglobulia we found a slightly increased plasma viscosity and an increase of the aggregation of the erythrocytes without decrease of their deformability. A decreased deformability of the erythrocytes in patients who underwent a transplantation with Pg and diabetes results in an additional risk, as was casuistically observed on a patient with 2 amputations of the legs and 2 myocardial infarctions. Our findings confirm the correctness of the isovolaemic haemodilution for the avoidance of additional cardiovascular complications in patients who underwent a transplantation of a kidney with polyglobulia.