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Hysterectomy, bilateral salpingo-oophorectomy & total colectomy for lynch syndrome. hybrid notes video-vignette.

We present the case of a 56-year-old female patient with a family history of multiple neoplasms, diagnosed with Lynch syndrome caused by mutation of the MSH6 gene. In a follow-up colonoscopy, several flat polyps were seen throughout the colon. Endoscopic resection was performed with the finding of a low-grade adenocarcinoma in a23 mm polyp resected from the rectosigmoid junction. Resection marginwas positive after endoscopic submucosal resection. Due to the presence of colon adenocarcinoma and a 70% risk of endometrial cancer associated with MSH-6 mutation, multidisciplinary team recommended a hysterectomy, bilateral salpingo-oophorectomy & total colectomy.