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Blood Pressure Responses at Exercise Onset in Postmenopausal Women

Exaggerated blood pressure (BP) responses at exercise onset may be characteristic of several cardiovascular diseases (CVD). Primary aging is a risk factor for CVD, and after menopause the prevalence of CVD is greater in postmenopausal women (PMW). Therefore, the purpose of this study was to test the hypothesis that BP responses at exercise onset are exaggerated in normotensive PMW compared to young women (YW). We retrospectively analyzed beat‐by‐beat BP and heart rate (HR) in 15 PMW (59±1yrs, 25±1kg•m2) and 16 young women (22±1yrs, 22±1kg•m2) in 10‐second intervals at the onset of isometric handgrip exercise at 30% of maximal voluntary contraction. Resting mean arterial BP (PMW: 87±3, YW: 84±3 mmHg, P>0.05) and HR (PMW: 62±2, YW: 66±2 bpm, P>0.05) were similar between groups. Systolic BP increased more in PMW (P<0.05), and tended to be higher at 30s of isometric exercise (PMW: Δ9±2 vs. YW: Δ5±1 mmHg, P=0.06). Mean arterial BP also tended to increase more in PMW (ANOVA P=0.12), whereas diastolic BP and HR responses were similar between groups (P>0.05). In conclusion, exaggerated BP responses at exercise onset may be associated with age and menopause.