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[Iodine availability, thyroid structure and function in residents of the city of Mirny, Republic of Sakha (Yakutia)].

Iodine availability for residents of the city of Mirny, Republic of Sakha (Yakutia), was estimated from urinary iodine and creatinine levels and their calculated ratio. Median of iodine/creatinine ratio in the groups of children and adults included in the study was 167.2 and 110.5 mcg/g respectively. Goiter was diagnosed by ultrasound in 0.4% of men and 4.9% of women. Diffuse and focal changes of the thyroid echographic pattern were revealed in the overwhelming majority of the examined subjects (91.7% of the adults and 66.1% of the children). The frequency of thyroid nodules was 5.0% and 20.3% in men and women respectively. Serum TSH level exceeded the respective reference values in 10.9% of the men and 18.2% of the women.