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Therapeutic strategy for acute stroke--prologue for an epoch of brain attack--. Acute stroke therapy based on Japanese guidelines for the management of stroke 2004.

Introduction The first guidelines for the management of stroke were reported in 1994 by the American Heart Association, and these were followed by the evidence-based guidelines from the Royal College of Physicians in the United Kingdom. However, because there may be racial differences, as well as differences in approved therapeutic agents, and disease subtypes between Japan and other countries, these guidelines can not necessarily be directly adopted into clinical practice in Japan. That was the reason why we created the first Japanese stroke guidelines, taking into consideration the detailed evidence and experience accumulated in Japan. Further, problem areas in the clinical study of stroke were expected to be clarified through the process of creating these guidelines.