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Zika virus outbreaks and treatment in pregnant women in Ho Chi Minh City, Vietnam

2 owing to ovarian failure). There were 29 patients with a BMI below 25, 45 patients with a BMI of at least 25 but less than 30, and 61 patients with a BMI of at least 30. The prevalence of obesity in the study group was 45.18%. All patients except two underwent ovulation induction with clomiphene and 15 of these patients also had injections of gonadotropins. There were four patients who had IUI and 16 patients had IVF. Only four patients of the patients who underwent IVF achieved pregnancy and none did following IUI. Pregnancies were recorded among 14 (48%), 14 (31%), and 14 (23%) of the patients with a BMI of under 25, at least 25 but less than 30, and of at least 30, respectively. In comparison with patients with a BMI below 25, a decreased likelihood of pregnancy was recorded among patients with a BMI of at least 25 but less than 30 (odds ratio 1.40, 95% confidence interval 1.22–3.72) and at least 30 (odds ratio 3.07, 95% confidence interval 1.19–7.81) (Table 1). However, the difference recorded among patients with a BMI of at least 30 was statistically significant (P=0.024). The results of the study are consistent with previous studies.2–4 The present study demonstrated an inverse relationship between increasing BMI and pregnancy rate in patients with infertility. With increasing obesity prevalence worldwide, and especially in the gulf region, preconception counseling and weight loss are highly recommended before using assisted conception methods to optimize outcomes. AUTHOR CONTRIBUTIONS