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Left ventricular hypertrophy as a coronary risk factor.

Left ventricular hypertrophy (LVH) is one of the most powerful risk factors known for cardiovascular disease. It is associated with impaired left ventricular filling, ventricular ectopy, impaired left ventricular contractility, and myocardial ischemia. Myocardial ischemia has a multifactorial pathogenesis and results from an increased oxygen demand (due to increased hemodynamic burden and increased muscle mass) and a decreased oxygen supply secondary to microvascular disease and coronary artery disease.