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Musculoskeletal and neuropsychiatric manifestations are the main source of persisting affection and organ damage in a German population of patients with systemic lupus erythematosus

In comparison to previous decades, the prognosis of patients with systemic lupus erythematosus (SLE) has improved significantly (1, 2). This is associated with a reduced rate of terminal renal failure, in comparison to earlier years, in patients with lupus nephritis, probably because of earlier diagnosis and treatment of kidney involvement in SLE (3). As a result of this process the clinical problems that have