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[Characteristics of anti-respiratory syncytial humoral immunity during persistence of respiratory syncytial virus antigens in adult patients with chronic obstructive bronchitis].

Specific humoral immune response has been studied in 8 patients with chronic obstructive bronchitis, in whom the persistence of RSV was detected, and in a group of patients without RSV persistence. Humoral immunity in patients with RSV persistence vs. those with acute and chronic bronchitis without viral persistence was characterized by the following features: a) earlier and more active production of IgG and, even more so, IgM and IgA; b) long persistence of high titers of anti-RSV IgG, IgM, and IgA-up to 17, 28, and 30 weeks, respectively; c) low anti-RSV neutralizing activity of serum antibodies.