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BIOCHEMICAL COMPOSITION OF DIFFERENT REGIONS IN BRAINS OF SMALL‐FOR‐DATE INFANTS

Different regions of the brains of babies born with low birth weights for the gestational age (small‐for‐date infants) were analysed for various chemical constituents. The brains of small‐for‐date babies were reduced in size. On a percentage basis, cerebellum and medulla oblongata were more affected than cerebrum. Cellularity, estimated by DNA content, was affected only in the cerebrum. However, the cell size and the concentrations of various constituents (proteins, lipids, different classes of lipids) studied in different regions of the brains of small‐for‐date infants remained unaffected compared to those found in the normal brains.