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Hematology Morphology Forum Case 1

A 75-year-old female was admitted with fatique, easy bruising and 1-month history of numerous nodular skin lesions (Fig. 1). The skin lesions were initially seen on the legs and subsequently generalized. She had been diagnosed with infiltrative ductal carcinoma which was treated with modified radical mastectomy 19 years ago. Her laboratory tests at the time of admission showed pancytopenia (Hb: 4 g/dl, WBC: 1300/mm, Plt 13,000/mm). Her general condition deteriorated very rapidly with GIT bleeding and confusion. A skin biopsy was performed with a presumptive clinical diagnosis of generalized breast cancer metastasis. The patient died shortly after the skin biopsy, a permission for autopsy could not be obtained.