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A Comprehensive Knowledgebase on Cancer Epigenetics

We have developed a cancer epigenetic marker database to facilitate the exploration of epigenetic proteins & their modulators which are involved in cancer. It is an interactive database of epigenetic protein families and different classes of epigenetic enzymes. This database comprises the information about protein families of cancer epigenetic markers, their structural data &known inhibitors, ADME properties etc. Regardless of the popularity of cancer epigenetic proteins in therapeutics, curated databases for relevant information on cancer epigenetics are lacking. Therefore, a cancer epigenetic database that provides a unique set of drug-like ligands, cancer epigenetic modulators, their ADMET parameters, supports searching based on textual information, and chemoinformatic investigations would be exceptionally useful for drug discovery researchers working in the area of cancer epigenetics. The vital reason for building up the database is to give an information platform to specialists intrigued by the field of cancer epigenetics. In general, this database will be valuable for drug designing and developing therapies for cancer.