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miRNA‐mediated crosstalk between Wnt3a and TGFβ3 in osteoblast differentiation

miRNAs play roles in regulating gene expression at the post‐transcriptional level through fine‐tuning of the protein‐encoding gene expression, and are involved mainly in regulating important biological processes in different cell and tissue types, including osteoblast differentiation. Canonical Wnt signaling is also known to play pleotropic roles in regulating cell differentiation during mammalian osteogenesis, although involvement of miRNAs is not established for Wnt signaling in osteoblast differentiation. We examined here the role of candidate miRNAs expressed differentially after Wnt3a expression during osteoblast differentiation.