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[Pathologoanatomic characteristic of primary and metastatic liver carcinoma].

Results of the analysis of primary and metastatic liver carcinoma, by using autopsied specimens in Rostov-on Don over 20 years are presented. The frequency of hepatocellular carcinoma was 0.4% among the deceased and 3.8% among all malignancies. There was a 1.8-fold rise in the frequency of hepatocellular carcinoma. The increase in the frequency of liver cancer correlated with that of liver cirrhosis on the autopsy specimens. 51.7% of cases of primary liver carcinomas developed in the presence of hepatic cirrhosis of various, including viral, etiology, 14.3% did in the presence of viral hepatitis. The paper presents the results of an immunohistochemical study and characterizes the markers that permit differentiation of primary and metastatic hepatic legions.