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Effects of Postnatal Maturation and Castration on Rat Epididymal Carbohydrate Metabolism 1

Summary An increase in epididymal weight and in pentose-shunt enzyme activity of glucose-6-phosphate and 6-phosphogluconate dehydrogenase occurred between 22 and 35 days of age in the rat. Both were prevented by castration. Further epididymal growth to day 60 in normal rats was associated with a decline in isocitrate dehydrogenase activity but no change occurred with the other enzymes. Glycogen concentrations in the epididymis declined in normal and castrated rats with increasing age.