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Trials and tribulations in prostatic cancer.

The unique prevalence of carcinoma of the prostate in the elderly male population (Franks, 1954), the ability to control (albeit temporarily) metastatic disease which for many other tumours would produce a hopeless situation (Resnick and Grayhack, 1975) and the long history of operative management of the primary tumour going back to the dawn of modern urology (Young, 1905) all affect in some way our perspective of the disease. It is subject to intense clinical and scientific study, but 80 years after the first radical prostatectomy and after 40 years of hormonal therapy, there remain many dilemmas in its management.