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[Pathogenicity of the opportunistic pathogenic fungus Cryptococcus neoformans--a review].

The increase of clinical fungal infection causes a wide awareness. Cryptococcus neoformans is one of the major fungal pathogens. In the past 10 years,much progress has been made in its molecular biological research, including the synthesis and mobilization of the virulence factors as well as the signal transduction pathways during pathogeny. All these will help prevent or treat this fungus. We review the virulence factors and the molecular biological research progress.