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The Neuroanatomy of HIV, How can Physical Activity Improve the Mental Health and Quality of Life in People Living with HIV

Motor‐Cognitive alterations (MCAs) are associated with HIV infection and antiretroviral therapy. These MCNAs are known to be related to the frontal lobe, cognitive and motor region involvement. MCAs create a profound negative impact on their independence causing a burden to caregivers and the health care system. MCNAs dysfunctions that impact motor speed, information processing, executive functions, attention, new learning, memory, and new information retrieval are distinct and particularly prominent traits of HIV. Furthermore, recent studies focusing on the role of HIV antiretroviral medication on MCAs revealed hypertension, depression and, peripheral neuropathy are among the top main comorbidities in Hispanic people living with HIV. All the aforementioned have a profound impact in mental health and quality of life in this individuals.