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Sequential External Beam Radiotherapy and High–Dose‐Rate Intracavitary Brachytherapy in T1 and T2 Nasopharyngeal Carcinoma: An Evaluation of Long‐Term Outcome

Objectives/Hypothesis: The standard treatment for nonmetastatic nasopharyngeal carcinoma (NPC) is external beam radiotherapy (EBRT), with or without chemotherapy. Because local control in NPC is an independent prognostic factor for distant metastases and survival, various dose‐escalation strategies have been used to reduce recurrences at the primary site. The objective of this report was to evaluate the outcome of adjuvant high–dose‐rate intracavitary brachytherapy (HDRIB) in patients with T1 and T2 NPC.