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Establishing Quantitative Within-Subject Confidence Limits For Clinical Stereoroentgenographs

It is now quite clear that under ideal conditions, discrete points can be located on x-ray films with standard deviations of less than 50 i. However, under routine clinical conditions, such considerations as individual variation in anatomy, movement of the subject between exposures, and variations in image quality combine to produce considerable reductions in the confidence which can be placed in quantitative assessments made from stereoroentgenographic films. This paper discusses some considerations involved in designing mathematical models in such a way as to optimize the use of imperfect data in answering specific clinical questions.