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Standardized serial photography in the assessment of treatment of advanced breast cancer.

Serial photography with strict technical control is used as a means of monitoring the response to treatment in patients with advanced breast cancer. Patient positioning, illumination, image scale, exposure and photographic processing conditions are considered. A simple means of enhancing the appearance of microvascular changes in the skin was devised to provide early detection of skin flush and nodules. Infrared absorption photography is being evaluated as another means of assessing the progress of the condition and its response to treatment. These techniques are part of a multilateral programme used to chart the progress of the disease. Serial photography was used in 39 patients. Photographic evidence was clinically useful in 28 patients and affected further clinical management in 8 cases.