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Diabetes Prevention Program in Youth (Insulin Superheroes Club) Pilot: Improvement in Metabolic Parameters and Physical Fitness After 16 Weeks of Lifestyle Intervention

Culturally tailored and comprehensive prevention strategies are vital for addressing the epidemic of obesity and rising rates of type 2 diabetes, particularly among ethnic and racial minority youth (1). The Diabetes Prevention Program (DPP) has demonstrated the efficacy of lifestyle modification in adults (2). However, studies on lifestyle programs for diabetes prevention in youth are limited, and none have reported comprehensive physical fitness outcomes (3–5). We conducted a pilot prospective uncontrolled study (ClinicalTrials.gov identifier NCT03042936) evaluating feasibility and changes in metabolic and physical fitness parameters for the Insulin Superheroes Club (ISC) curriculum, a DPP designed for youth from culturally diverse, minority backgrounds.

Youth aged 7–15 years and a parent with impaired glucose tolerance enrolled in the ISC as a supplement to the Centers for Disease Control and Prevention’s adult DPP. The ISC is a 12-month, multilevel program that includes 16 weekly (phase 1), 3 biweekly (phase 2), and 6 monthly (phase 3) sessions. Participants attended sessions that included 60 min of physical fitness and 30 min of education. The education portion included interactive …