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Novel treatment strategies for neurodegenerative diseases based on RF exposure

In this paper we propose a novel engineering approach in the treatment of neurodegenerative diseases, based on controlled radio frequency (RF) exposure. In recent experiments on mobile phone exposure of transgenic Alzheimer's disease (AD) mice, improved cognitive functions were observed, inspiring a possible regression of the disease after RF treatment. To this end, we define a parallelism between neuronal and communication systems, defining a conceptual RF-neuronal interface to exploit the impact of the electromagnetic (EM) induced currents on the cellular membrane, where the biological messages are generated. Preliminary simulation results confirmed this hypothesis. In a therapeutical perspective, controlled RF exposure is expected to affect the brain activity at networking level where, in AD patients, broken links between functional areas of the brain give rise to cognitive and behavioural dysfunctions. A possible solution is to restore the missing paths enhancing the neuronal activity by means of controlled RF exposure.