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MiRNA‐181a is a novel regulator of aldosterone–mineralocorticoid receptor‐mediated cardiac remodelling

The aldosterone–mineralocorticoid receptor (Aldo–MR) pathway is activated during cardiac stress, such as hypertension, myocardial infarction (MI), and heart failure. The importance of Aldo and MR in the pathogenesis of cardiac diseases is well established; however, the regulatory mechanisms behind Aldo/MR‐induced cardiac remodelling remain uncertain. We here investigated potential miRNA‐mediated regulation of the Aldo–MR pathway to improve mechanistic understanding.