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Hyperglycemia as a component of metabolic syndrome and the main important factor of its progression

The results of the investigation show that the primary disturbances of the carbohydrate metabolism, namely – a moderate hyperglycemia as a result of chronic glucose overload led to the complex of proatherogenic disturbances which are typical for an insulin resistance. It was also established the close connection between the syndrome components which is realized through such main mechanisms as hypertriglyceridemia (HTE) systemic inflammation and oxidative stress. These data show the independent significance of hyperglycemia as a factor which initiates the progression of metabolic syndrome.