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Suspected anti-N-methyl-D-aspartate receptor encephalitis in the setting of a 26-year-old female with an ovarian carcinoma

Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is an autoimmune encephalitis associated with ovarian tumors, rarely seen in emergency departments (EDs). There are proposed diagnostic methods and recommended treatment guidelines for anti-NMDAR, however, as this is a rare form of encephalitis, diagnostic, and treatment recommendations continue to be explored. We describe the case of a 26-year-old female patient who presented to our ED with altered mental status, exhibiting orofacial dyskinesias and choreathetoid movements. The patient was subsequently found to have an ovarian tumor and diagnosed with presumed anti-NMDAR encephalitis. The following core competencies are addressed in this article: Medical knowledge, Patient care.