{'fraction_non_alphanumeric': 0.02771855010660981, 'fraction_numerical': 0.006396588486140725, 'mean_word_length': 6.3359375, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Allo‐activated CD4+ and CD8+ lymphocyte subsets: New ultrastructural findings based on computer‐assisted image analysis

Abstract: Primary allo‐stimulation induces substantial and differentiated modifications in the development of cytoplasmic organelles of peripheral T‐lymphocyte subsets. The present computer‐assisted image analysis provides evidence that the CD4 + subset undergoes significant increase in organelle density after stimulation, while the CD8 + subset exhibits a post‐stimulation organelle development proportional to the cell size. Each immunological subset contains two distinct patterns of cytoplasmic organization, here defined as type I (containing a few cytoplasmic organelles) and type II (with well‐developed synthesis and storage organelles). On the basis of these findings cytologic parameters could be ascribed to a heterogeneous proliferation of functionally distinct T‐cell clones in CD4 + and CD8 + subsets.