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The BamHI Restriction Fragment Length Polymorphism Detected in the c‐Ha‐ras Locus of Human Skin Tumors

By means of Southern blot hybridization, 13 human primary skin tumor tissues were analyzed for activated forms of three cellular oncogenes, c‐Ha‐ras, c‐myc, and c‐erbB. In the c‐Ha‐ras oncogene, a BamHI restriction fragment length polymorphism was found among human skin tumors, but it is not clear whether it is related to the malignancy of tumors selected for this study. We were not able to detect the activated forms of the three oncogenes used in this study.