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Modulation without surgical intervention

Noninvasive deep brain stimulation can be achieved via temporally interfering electric fields A multitude of brain disorders have debilitating impacts on the quality of life of a large patient populace, accounting for ∼30% of the global burden of disease (1). Most patients with brain disorders are unamenable to any form of treatment when first- and second-line interventions are ineffective (2, 3). Neuromodulation technologies can help millions of patients who suffer from such brain disorders.