{'fraction_non_alphanumeric': 0.022341376228775692, 'fraction_numerical': 0.009830205540661306, 'mean_word_length': 5.627218934911243, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Study of hormonal receptors in dystrophic mice muscles

This study was designed to assess and characterize the steroidal hormone receptors in skeletal muscle of dystrophic mice. Mdx mice are a model of Xp21 dystrophin‐deficient muscular dystrophy. Five mdx and five C57BL6 (control) mice four months old were used. Muscles, including heart, gastrocnemius, diaphragm, quadriceps, soleus and extensorum digitorum longus (EDL) were dissected, frozen in liquid nitrogen. PCR amplification was carried out to assess the steroidal receptors mRNA expression. Mdx mice showed significant raise in the expression of steroidal receptors mRNA when compared to the C57BL6 mice: androgens receptors in heart, alpha estrogen receptors in EDL and beta estrogen receptors in quadriceps were increased. In addition, significant lowered levels of some other hormone receptors were found: corticosteroid receptors in EDL and alpha estrogen receptors in quadriceps, leading to the conclusion that dystrophic muscles disclose significant differences on hormone receptors, when compared to C57BL6 strain. There was no support for this study.