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Impact of obstructive sleep apnea-hypopnea syndrome on left ventricular function in children

Objective To investigate the effect on the left ventricular systolic function and the diastolic function in children with obstructive sleep apnea-hypopnea syndrome (OSAHS) by Doppler echocardiogram in our present study.Methods There were 51 child patients with sleep disorders or snoring who were performed polysomnography (PSG) for the diagnosis.according to the results of examination.They were divided into the OSAHS group (29 cases) and the primary snoring (PS) group (22 cases).Doppler echocardiogram examination was carried out in two groups respectively;the major index included:the left room minor axis contraction (LVFS),the left room shoots the menstruation number (LVEF),to wrestle the output every time (LVSV),the diastolic early time peak value blood stream speed (MV E),the later period peak value blood stream speed (MV A) and MV the E/A ratio.The analysis compared the change of these parameters and their relationship with the OSAHS.Results The data demonstrated that comparison between OSAHS group and the PS group showed:(1)(Apnea hypopnea index )AHI (13.2 ±9.2 to 1.2±1.1) of OSAHS group was higher than the PS subjects (P0.05);lowest oxygen saturation (LSaO2) (78.5 ±5.4 to 87.4 ±3.7) was lower than the PS group (P0.05);(2)OSAHS group later period peak value blood stream speed (MV A) (0.62±0.1 to 0.57±0.1) was higher than PS group (P0.05);E/A ratio of OSAHS group (1.58±0.24 to 1.73±0.25) was lower than the PS subjects (P0.05).(3)In OSAHS group M E/A value and LSaO2 (R=-0.527,P0.05) was negatively correlated.Conclusion OSAHS can affect the children left ventricular diastolic function,but it has no effect on systolic function.The Doppler echocardiogram is one of the most important methods in monitoring heart function is OSAHS children,and what's more,it may indicate whether the children suffer from damage to moulding and diastolic and systolic function of left ventricle.It has important value to judge the degree of OSAHS and prognosis.