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Kin-Founding and the Fixation of Chromosomal Variants

Founding of populations by kin groups can greatly increase the probability of fixation of chromosomal variants compared to a group founded by a group of unrelated individuals. A kin group is more likely to have a high initial chromosomal frequency, a factor that increases the eventual probability of fixation of that variant. Kin-founding may be an important factor explaining the relatively high rate of chromosomal substitution among many populations and species.