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Effect of low‐dose supplements of menaquinone‐7 (vitamin K2) on the stability of oral anticoagulant treatment: dose–response relationship in healthy volunteers

Despite the worldwide use of vitamin K antagonists (VKAs), there is limited knowledge of the influence of dietary vitamin K on anticoagulation control. In view of the increasing nutraceutical availability of menaquinone‐7 (MK‐7; vitamin K2) and its promotion for bone and cardiovascular health, it is important to determine the posology for the interference of supplemental MK‐7 with VKA therapy.