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Evaluation of Signal Quality from a Wearable Phonocardiogram (PCG) Device and Personalized Calibration

Currently, the only clinically utilized Phonocardiogram (PCG) is an electronic stethoscope used in a hospital or clinical environment. The availability of continuously recorded PCGs can provide a new avenue of research into chronic disease management at home. Researchers have proposed such wearable PCG devices. However, limitations exist in evaluating such devices as PCG recording devices in home-like environments. Here, we evaluate a wearable PCG system in a belt-type form factor with an embedded force sensor, accelerometer, and a single lead ECG to study the feasibility of acquiring diagnostic-grade PCGs while the wearer performs daily activities. We describe qualitative and quantitative exploratory analysis methods for cross-subject comparison of PCG signal quality, wearer comfort, and the impact of activities using Signal-to-Noise (SNR) comparisons and cross-spectral coherence between activity and PCG. The analysis of the data suggests that a common user-chosen method of donning a wearable PCG is not applicable across subjects for obtaining optimal PCG recording quality. We propose a method to calibrate wearable PCG devices using an embedded force sensor and by following a protocol involving feedback from the embedded force sensor to determine the optimal method of wearing the device. Following a similar path to precision medicine using genomic data and the extrapolation of risk, wearable devices with healthcare applications should be developed with the ability to be adapted and calibrated to each individual. In the immediate future this may involve calibration procedures such as those followed in this work, using controlled measurements performed with each patient to tune a device for them.