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Infectrons and coevolution.

1 Laboratórios de Imunologia Celular e de Malária, Faculdade de Medicina, Universidade de Brasília, 70910-900 Brasília, DF, Brasil Recebido para publicação em 19/2/2001. Infectious agents are everywhere, in our outer and inner surfaces, in our body fluids, tissues and cells. They dwell the uppermost of our individuality: our genome. Indeed, it has been recognized that about 40% of mammalian genome is composed of retrotransposons derived from retroviruses10 17, some integrated to host genome for millions of years12. It is proposed that this extensive and prolonged association between humans and microbes generates diversity and mutual adaptation and, consequently, coevolution.