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Physical activity “responders” vs “non-responders” after exercise training with air or oxygen in people with COPD and exercise-induced desaturation

Aim: To evaluate changes in physical activity (PA) following exercise training on air or oxygen in people with COPD and EID. Methods: Secondary analysis of data from the "suppORT" trial was performed. COPD participants who desaturated to SpO2 Results: 87 participants [mean (SD) age 70 (8) years; FEV1 48 (18)% predicted] completed training (OG n=48; AG n=39). There was no significant difference in the change in PA after training in the OG compared to the AG (mean difference (95% CI) of 333 steps/day (-164 to 831)). Twenty participants (18%) were responders (12 in the OG (25%), 8 in the AG (21%)). The responders had a mean improvement of 1,307 (753) steps/day compared to a 523 (909) steps/day decline in non-responders (p Conclusion: Most people with COPD and EID did not demonstrate an increase in PA following individually-prescribed exercise training on air or oxygen.