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UK National Transplant Database retransplantation in the UK and Republic of Ireland, 1987-1996. UKTSSA National Transplant Database.

At the end of 1996, 1,635 kidney, 17 liver and 24 cardiothoracic recipients were registered on the UK and Republic of Ireland national transplant waiting list to receive a second or subsequent transplant. These patients represented 20%, 9% and 4% of the total separate waiting lists, respectively. This clearly demonstrates a continuing requirement for retransplantation. A study of the characteristics of first and retransplant recipients and their donors shows that retransplant recipients tend to be younger and in the case of liver and heart/lung transplants are less likely to be male. Survival of liver regrafts is significantly worse than first transplant survival. Multifactorial analysis of the factors affecting the outcome of kidney retransplants showed outcome to be associated with the survival time of the first transplant. In the case of kidney transplantation, the younger and the better matched recipients selected for retransplant may at least partially explain the comparable one-year transplant survival estimates for first and retransplants of 81% and 78%, respectively, for the 1986-1993 dataset of 23 centers.