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Structurally Sensitive Changes in Absorption THz Spectra of Corticosteroids

The series of steroid hormones, such as progesterone, 17α-hydroxyprogesterone, cortisol and other was measured by terahertz time-domain spectroscopy (THz TDS). It was obtained that THz absorption spectra of steroid hormones have characteristic lines of absorption in the frequency range 0.1-3.0 THz. We investigate the relation between the position of side functional groups and THz spectral response. Besides pellets of polycrystalline pure substances, steroids solution in methanol was analyzed. The given method can be applied for express diagnostics of different classes of steroid