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Evaluation of chlorhexidine gel combined with platelet-rich fibrin "PRF" in reducing alveolar osteitis after removal of impacted mandibular third molar.

Objectives: To evaluate the effect of chlorhexidine gel combined with platelet-rich fibrin “PRF” in reducing alveolar osteitis after removal of impacted mandibular third molar. Subjects and methods: Forty two patients were divided randomly into three groups: Group A: the socket received 0.2% CHX gel and PRF. Group B: the sockets received PRF only. Group C (control): the sockets did not receive any treatment. Follow up: 2, 7 and 15 days post-operative for evaluating alveolar osteitis, pain, facial swelling, mouth opening and wound healing. Results: At the present study, reduction of alveolar osteitis incidence in group A in comparison to group B (7.6%) and group C (30.7%). There were significant reduction in pain between groups in 2 days and 7 days. There was no difference in facial swelling, maximum mouth opening. Follow up: after 3 months for evaluating bone density at the site of extraction and the result were increase in bone density in group A and group B in comparison to group C. Conclusion: Chlorhexidine gel combined with platelet-rich fibrin “PRF” reduce pain and decrease the incidence of AO.