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Protein losing enteropathy: causes, clinical signs and diagnosis

Protein losing enteropathy (PLE) is a syndrome associated with several gastrointestinal (GI) diseases in dogs and, less commonly, in cats. The condition varies in severity from mild to severe, with sometimes life-threatening complications such as pulmonary thromboembolism. This article discusses the causes, clinical signs and methods of diagnosis of PLE. Treatments of the more common causes are also considered, along with prognoses.