{'fraction_non_alphanumeric': 0.017346938775510204, 'fraction_numerical': 0.0, 'mean_word_length': 5.86013986013986, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Postacute stroke treatment

Mechanisms by which the damaged brain might recover from stroke include neural rewiring and endogenous progenitor (stem) cell proliferation in brain. Polypeptide growth factors stimulate these processes and may be useful as treatments to enhance neurological recovery after stroke. For example, in preclinical studies, we have shown that exogenously administered basic fibroblast growth factor (bFGF) stimulates sprouting from undamaged neurons and stimulates endogenous progenitor cell proliferation in the rat brain following focal cerebral infarction. These effects are paralleled by an enhancement of recovery of sensorimotor function of the contralateral limbs. Recent data have been obtained using a covalently dimerized bFGF (dFGF), which appears to be more stable and potent than the monomer. Growth factors may represent treatments that can be administered subacutely (days or weeks) following stroke in order to enhance neurological recovery.