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Cholesterol homeostasis actors and survival time after glioblastoma surgery (825.4)

Background and objective: Lipid composition has been related to the malignancy grade of glial human tumors. Activation of LXR (Liver X Receptor) by nutrients in cancer cells may lead to cell deprivation in cholesterol, inhibition of proliferation and stimulation of apoptosis. The goal of this study is to relate the expression of some proteins driven by LXR with survival time in glioblastoma (GBM).