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Electrospun Proteoglycan Matrices for Tracheal Tissue Engineering

Decorin (DCN) is a proteoglycan (PG) present in the extracellular matrix (ECM) of many tissues, including the trachea. Electrospinning is a suitable method for three‐dimensional (3D) scaffold fabrication to mimic the ECM's fibrous structure. In this study, we generated electrospun DCN‐polymer hybrids to obtain scaffolds that allow human tracheal cell (hTC) seeding.