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Sympathetic stimulation causes increased output of lymphocytes from the popliteal node in anaesthetized sheep

Stimulation of the lumbar sympathetic chain at a frequency of 4 Hz caused a threefold increase in the lymphocyte output in efferent lymph from the popliteal node in anaesthetized sheep. The increase was accounted for by a rise in both lymph flow and lymphocyte count. Intra‐arterial infusion of phentolamine (10 micrograms kg‐1 min‐1) abolished the nerve‐mediated increases in flow and cell count.