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Prenatal diagnosis of genetic skin disease by fetoscopy and electron microscopy: report on 5 years' experience

Since our first report 5 years ago (Rodeck, Eady & Gosden, 1980) the combination of fetoscopy and electron microscopy to obtain and examine fetal skin biopsy specimens has become an established method for assessing mid‐trimester fetuses at risk for different genodermatoses characterized by specific ultrastructural abnormalities. Our present report concerns 39 fetuses ( Table ).