{'fraction_non_alphanumeric': 0.029133858267716535, 'fraction_numerical': 0.011023622047244094, 'mean_word_length': 5.551546391752577, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Use of Hemodiafiltration in Children

An optimal elimination of uremic toxins with a good tolerance in a short session time is the aim of all extrarenal dialysis, especially in children. The first report of attempts to dialyse a child with chronic renal failure appeared in 1966 ( I ) . Since then, advances in dialysis technology (ultrafiltration control system, bicarbonate buffer dialysate, highly permeable, and biocompatible membranes) have permitted reduction in treatment time and optimization of dialysis efficiency (2). Hemodiafiltration (HDF) is a new dialysis modality first introduced in adults by Leber and Wiezemann in 1976 (3). HDF combines hemodialysis (HD) and hemofiltration simultaneously, which allows blood purification by both a diffusive process and by convective mass transport. We have used HDF in children since 1982. The goal of HDF use in children., as a chronic dialysis therapy is (i) to optimize uremic toxin extraction with low and middle molecular weight compound removal approaching glomerular filtration; and (ii) to shorten the individual session time with the optimal use of highly permeable membranes (dialysate purity) while facilitating low dialytic patient morbidity, especially cardiovascular stability (hemofiltration effects).