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A review of current evidence from cardiovascular manifestations and outcomes in patients with COVID-19.

BACKGROUND
In 2019, acute respiratory syndrome related to COVID-19 occurred as a global epidemic problem. The COVID-19 pathogenesis method is by using enzyme 2-converting enzyme angiotensin ACE2, which infects host cells, which is resulted in some organs, involving the lungs, heart, kidneys and intestines According to reports from the first signs of involvement of the cardiovascular system in various forms, the involvement of Cardiovascular injuries. The aim of this study was to evaluate the cardiovascular manifestations in COVID-19 disease.


METHODS
In this study with help of medical science database (Scopus, PubMed and etc.) for gathering of basic information and recent reports of COVID-19 disease in all over the world. All the data collected from the databases were identified and evaluated so that the evidence could be fully reported and ultimately a general conclusion could be reached.


RESULTS
Cardiac complications in patients with COVID-19, could be caused by several mechanisms, some of which overlap, e.g., IL-6 and inflammation. Direct viral cardiomyocyte invasion, with unopposed angiotensin II effects, immune activation, microvascular dysfunction, or increased metabolic demand, could contribute to the to heart damage.


CONCLUSION
COVID-19, in turn, can exacerbate cardiovascular damage Along with other symptoms of for COVID-19. If care services, medical and treatment facilities, as well as the care team provide the required care and treatment in a timely manner, it will lead to the reduction of mortality rate.