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Two subpopulation of human Purkinje neurons: an electron microscopy study.

Conventional electron microscopy of human cerebellar cortex has revealed two types of Purkinje neurons with different staining intensities. The light-stained type constitute the major type and both types have similar diameters. This finding was not reported in human before but in lower mammalian. Whether the different staining pattern of Purkinje neurons implies a specific histo-functional aspect a pathological one or histological artifacts is not known.