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The Digoxin Index 1966–1981 Part III

Red Cells 1969 I. Ellory JC, et al. Binding of tritiated digoxin to human red cell ghosts. Nature 1969;221:776. 1971 2. Cohen HC. Digoxin and digitoxin in man: influence on rubidium transport in red blood cells in vitro. Acta Cardiol (Brux) 1971;26:443-57. 1972 3. Hibble AG, et al. The plasma digoxin concentration, red cell rubidium 86 uptake and control of ventricular rate in patients being digitalized for atrial fibrillation. Clin Sci I972;42:P3P. 4. KettlewellM, et al. Effect of digoxin on human red blood cell electrolytes. Br J Pharmaco/1972;44:165-7. 1973 5. Gardner JD, et al. Effects of digoxin-specific antibodies on accumulation and binding of digoxin by human erythrocytes. J Clin Invest 1973;52:1820-33. 1974 6. Astrup J. Changes in sodium and potassium in human red cells in vivo related to treatment with digoxin, to hypokalemia, and to cell density. Ann NY Acad Sci 1974;242:693-702. 7. Astrup J. The effect of hypokalemia and of digoxin therapy in red cell sodium and potassium content. Some clinical aspects. Scand J Clin Lab Invest 1974;33:I1-16. 1978 8. Loes MW, et al. Relation between plasma and red cell electrolyte concentrations and digoxin levels in children. N Engl J Med 1978;299:501-4. 1979 9. Ford AR, et al. The acute changes seen in cardiac glycoside sites, 86 rubidium uptake and intracellular sodium concentrations in the erythrocytes of patients during the early phases of digoxin therapy are not found during chronic therapy: pharmacological and therapeutic implications for chronic digoxin therapy. Br J Clin Pharmacol 1979;8:135-42. 10. Ford AR, et al. Changes in cardiac glycoside receptor sites, 86 rubidium uptake and intracellular sodium concentrations in the erythrocytes of patients receiving digoxin during the early phases of treatment of cardiac failure in regular rhythm and of atrial fibrillation. Br J Clin Pharmaco/1979;8:125-34. I I. Ford AR, et al. The characteristics of the binding of 12-alpha3H-digoxin to the membranes of intact human erythrocytes: relevance to digoxin therapy. Br J Clin Pharmacol 1979;8:115-24.