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Radioxenon Retention in the Early Diagnosis of Respiratory Burns

A simple scintigraphic technique is described to detect regional pulmonary retention of 133Xe 90 seconds after an intravenous injection. Regional retention accurately reflected distal airway damage due to thermal inhalation injury. In the early diagnosis of respiratory burns, this procedure supplements fiberoptic bronchoscopy which primarily detects proximal airway injury. Simultaneous pulmonary perfusion scintigraphy may assist in the diagnosis of pulmonary embolism which has a reported high incidence in respiratory burns.