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Negative middle ear pressure and hearing thresholds in secretory otitis media. A double-blind crossover study with Lunerin.

No significant effect of an oral decongestant (Lunerin: brompheniramine maleate and phenylpropanolamine hydrochloride) can be shown in this study. Negative middle ear pressure, effusions in the middle ear and hearing threshold levels were evaluated in 26 cleft palate children over a 3 month period, applying a double-blind crossover method. Variations in middle ear pressure occurred in all patients during the trial. The shape of the tympanograms gave no information additional to the clinical evaluation.