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“TEST YOUR UNDERSTANDING OF NEUROPHYSIOLOGY”. 1st Edition. R.W. Murray (1983) Cambridge University Press, Cambridge. 291 pages. $62 (Cdn. hardback) $21 (Cdn. paperback).

Most of the presentations utilize computerized analysis of EEG data. The analog EEG signal for these data has been collected from two to over forty separate scalp recording sites. Some studies examine simple averaged evoked potentials from a limited array of scalp electrodes. Others attempt a toposcopic assessment of various evoked potential components. Many of the papers are based on digitization of the analog EEG signal and derivation of power spectral data using a fast Fourier transform for initial data reduction. The spectrum is then divided into "classical" (alpha, delta, theta, beta) frequency bands and the spectra in these bands is viewed as a probability density distribution. Relative and absolute power of these bands and their variabilities following drug administration are correlated and profiles or "fingerprints" for various classes of drugs and their dose-response-time relationships studied. (Drugs studied include tranquillizers, hypnotics, enkephalins, as well as antidepressant and antiepileptic preparations.) The conclusions based on these EEG statistical manipulations should be viewed with skepticism since complex changes within these frequency bands are difficult to interpret in a meaningful way. In other words the physiological and behavioral correlates of these changes are tenuous at best.