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[The effect of specific immunotherapy on bronchial hyperreactivity in patients with bronchial asthma].

The aim of the paper was to answer the question, weather specific immunotherapy affected bronchial hyperreactivity in asthmatic patients. The authors used their own results of specific immunotherapy studies and those found in the literature. From these data the following conclusions were formulated: 1. Specific immunotherapy decreases specific bronchial hyperreactivity. The improvement is seen both in the early and late asthmatic reactions. 2. No significant effects of specific immunotherapy on nonspecific bronchial hyperreactivity were found. 3. In order to find an unequivocal answer to the question above multicenter studies on a representative group of patients based on the same protocol and lasting for at least 5 years are necessary.