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STRUCTURAL TRANSFORMATION OF CHICKEN LIVER UNDER THE INFLUENCE 
OF THE VIRAL FACTOR ON THE BACKGROUND OF MITOFEN APPLICATION

The paper presents the results of studies on histological and morphometric transformation in the liver of chickens during experimental infection with a virulent strain of infectious bursal disease virus (IBD) and the use of the antioxidant mitofen. It was found that during the experimental infection of chickens with the IBD virus strain, pathological processes associated with metabolic disorders were revealed in the liver of chickens – granular, fine-droplet fatty and vacuolar de-generation, as well as cell edema, deformation of the nucleus, the predominance of the stromal processes over paren-chymal ones. When using mitofen, the morphometric parameters were characterized by the normalization of the cellular components of the liver. At the same time, the size of hepatocytes increased, the number of binuclear cells increased, and the density of the content of liver cells per conventional unit of area increased.