{'fraction_non_alphanumeric': 0.03317972350230415, 'fraction_numerical': 0.01566820276497696, 'mean_word_length': 5.170454545454546, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
[Current concept of the hormonal state in menopause].


 Current hypotheses concerning hormonal conditions during menopause are discussed. Estrone, estradiol, and total estrogen appear to remain unchanged in the various age groups (age 50-80) after menopause. Urinary total estrogen levels also remain without significant changes before and after ovariectomy during menopause (7.9 and 7.0 mcg/24 hours, respectively), except in case of hyperplasia of the stroma (13.3 and 8.9 mcg/24 hours, respectively). It is uncertain whether the ovaries are capable of producing steroids, especially estrogen, or only their precursors, and in the latter case, which appears more likely, whether the following stages in their production take place in the adrenal glands or in the peripheral tissues. Only preliminary studies are available and further research will be needed to clarify present findings, which are sometimes contradictory. It is possible that the adrenal glands may produce, instead of complete estrogen, further precursors, which would be added to those synthesized in the ovaries.
