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Serological confirmation of group C streptococcal pneumonia.

Lancefield group C streptococci are a common cause of infections in animals but less frequently cause disease in humans. Studies by Duma [1] and Mohr [2] showed that only O^o-OJ^o of streptococci isolated from cultures of human blood were identified as group C. Pneumonia due to group C Streptococcus has been reported in eight individuals [2-7]: five patients were previously healthy, one was a chronic smoker, one had a hiatus hernia and a bleeding esophageal ulcer, and one had underlying Hodgkin's disease. We describe a patient with pneumonia due to group C Streptococcus, peritonitis with underlying congenital heart disease, and chronic renal failure who was receiving continuous ambulatory peritoneal dialysis. The etiologic role of the group C Streptococcus in the illness of this patient was confirmed by isolating the organism from the blood and peritoneal fluid and by demonstrating a significant rise in antibody titer to group C streptococcal carbohydrate antigen in convalescent sera.