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Late Rise Human Chorionic Gonadotropin after Embryo Transfer: Causality and Significance! A mini review

The reliable detection of hCG in maternal blood usually coincides with the embryonic implantation phase which is around 7 days post fertilization. It is believed that hCG levels taken post embryo transfers have a diagnostic and prognostic value when it comes to reproductive outcomes. Very low initial hCG levels predict a higher risk of chemical pregnancies, miscarriages and ectopic pregnancies. A review of the literature was performed so as to understand the mechanisms leading to late hCG rises as well as significance of such findings.