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Squamous cell carcinoma in situ of the vulva. A clinical and histopathological study.

Twenty-nine patients with squamous cell carcinoma in situ of the vulva have been followed 3–20 years. In 21 patients pruritus, usually combined with soreness was the main symptom. Colposcopy was performed in 12 cases with pathological vascular pattern in 7. Three patients had multiple-lesions in the vulva, and 4 had a concomitant carcinoma in situ of the cervix. Only one recurrence was detected after 62 months in a patient with atypical epithelium at the resection border. Carcinoma in situ of the vulva is a relatively innocent condition that should not be overtreated. The standard treatment should include a wide local excision.