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Update on MALDI-TOF MS Identification of Filamentous Fungi.

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) based species identification has found its place in many clinical routine diagnostic laboratories over the past years allowing significantly reduced turnaround times and high-precision results. With regard to MALDI-TOF MS for filamentous fungi, here we discuss different approaches of sample processing and growth conditions before analysis. In particular, we review the performance of different commercially available databases as well as the potential of complementary (self-constructed) in-house databases.