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The extrahepatic consequences of cirrhosis.

Cirrhosis represents the end stage of all chronic liver disease, regardless of etiology. Histologically, cirrhosis is defined by the presence of progressive liver fibrosis with nodular regeneration and distortion of hepatic architecture. Clinically, patients with cirrhosis develop portal hypertension that may affect multiple organ systems with increased morbidity and mortality. This article focuses on the extrahepatic consequences of cirrhosis. 
 
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