{'fraction_non_alphanumeric': 0.03939393939393939, 'fraction_numerical': 0.0030303030303030303, 'mean_word_length': 5.981873111782478, 'pattern_counts': {'":': 0, '<': 1, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Associations of abdominal visceral and subcutaneous adipose tissue with clinical and computed tomography imaging markers of metabolic syndrome

Aim: Central obesity comprises visceral (VAT) and subcutaneous (SAT) adipose tissues, which were reported to have associations with metabolic syndrome. Abdominal computed tomography (CT) scan allows evaluation of VAT, SAT, hepatosteatosis, pancreatic steatosis, and aortoiliac atherosclerosis. We aim to investigate the relationship between central obesity components (VAT, SAT) and metabolic syndrome imaging markers that are detectable on abdominal CT and the predictive power of these parameters for detecting hypertension (HT), diabetes mellitus (DM), and dyslipidemia (DL). Materials and Methods: Abdominal CT scans of 321 patients were evaluated for VAT, SAT volumes, hepatosteatosis, pancreatic steatosis, and aortoiliac atherosclerosis in this retrospective cross-sectional study. The associations of VAT, SAT, and visceral-tosubcutaneous fat (V/S) ratio with HT, DM, DL, hepatosteatosis, pancreatic steatosis, and aortoiliac atherosclerosis were investigated by Mann-Whitney U test, Kendall's Tau-b test, and boosting linear regression analysis. Cut-off values of VAT, SAT, and V/S ratio were calculated to predict HT, DM, DL, hepatosteatosis, pancreatic steatosis, and aortoiliac atherosclerosis by receiver operating characteristic (ROC) curve analysis. Results: Increased VAT volume and V/S ratio were significantly related to HT, DM, DL, hepatosteatosis, pancreatic steatosis, and aortoiliac atherosclerosis (p<0.001). Increased SAT volume showed significant correlations to HT, iliac atherosclerosis, hepatosteatosis, and pancreatic steatosis. VAT volume and V/S ratio predicted HT, DM, and DL with diagnostic accuracy ranging from sufficient to good. Specifically, VAT volume predicted hepatosteatosis with a very good diagnostic accuracy. Conclusion: VAT volume and V/S ratio are related to clinical manifestations and abdominal CT markers of the metabolic syndrome with a more substantial relationship present with VAT. Reported cut-off values could be utilized to detect metabolic syndrome earlier, which would provide early lifestyle alterations aiming at a lesser fat percentage in body weight, leading to decreased morbidity and mortality rates.