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Childhood cancer survivors face greater risks of subsequent malignant neoplasms from human papillomavirus

Although most HPV infections do not lead to cancer, several oncogenic types of HPV— most often HPV16 and HPV18— can cause cervical, vaginal, vulvar, anal, penile, and oropharyngeal cancer. Because of emerging evidence showing that childhood cancer survivors face an elevated risk of SMNHPVs, a group of researchers from several leading children’s cancer centers investigated the factors that influence their risk of developing an SMNHPV.