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Scleral Nodule and Bilateral Disc Edema as a Presenting Manifestation of Systemic Sarcoidosis

Aim: To report a rare presentation of a large scleral nodule with bilateral disc edema as the initial manifestation of sarcoidosis. Materials and Methods: Retrospective interventional case report. Results: A 58-year-old woman was referred for evaluation of nodular scleritis. Slit-lamp examination showed a large scleral nodule superiorly in the right eye. Fundus showed bilateral disc edema. High-resolution computed tomography of the thorax showed mediastinal and bilateral hilar lymphadenopathy. Transbronchial lymph node biopsy showed epitheloid granulomas. The scleral nodule and disc edema resolved at 6 weeks with oral steroids. Conclusions: This case highlights a rare presentation of a large scleral nodule with bilateral disc edema as the initial manifestation of systemic sarcoidosis.