{'fraction_non_alphanumeric': 0.02058165548098434, 'fraction_numerical': 0.006263982102908278, 'mean_word_length': 5.043243243243243, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
LATE-ONSET HMSN 2: FURTHER EVIDENCE OF GENETIC HETEROGENEITY

Ontaneda that each mutually exclusive race/ethnic group used in our study may contain a tremendous amount of genetic and cultural heterogeneity. Our study utilized existing data that were catalogued to the National Alzheimer’s Coordinating Center. Using the US Census questions, Hispanic/Latino ethnicity is asked first since the assumption is that Latinos can be of any race. In this data set, 66% of the individuals who were of Hispanic ethnicity were categorized as Other race, 30% were of white race, 3% were of black race, and less than 1% were of Asian or American Indian race. National data would indicate that the proportion who self-categorize as white is closer to 50% and about 40% are of other race, probably reflecting the admixed nature of the Latino population. Our study reported data on all Latino individuals, those who were of Hispanic ethnicity and of any race category together. We did not have information on whether subjects were mulatto (mixed white and black race) or Mestizo (mixed white and indigenous). Future studies with race/ethnicity as a focus should strive to disaggregate race/ethnic groups as much as possible to reflect genetic, cultural, and social diversity within any broad categorizations of race. However, there is a risk that further disaggregating the categories will lead to such small numbers that little can be concluded about any of the groups. Available genetic data actually support the geographic origin of race in the categories used by the US Census. Furthermore, the Latino/Hispanic population has been admixed for 500 years and resulted in a unique population group that merits separate category from a genetic perspective. From a cultural and social perspective, there is ample evidence that Latinos/Hispanics share more common characteristics as an immigrant group in the United States than differences rooted in national origin and racial admixture. The US Census categorization is legitimate and facilitates analyses of available data such as ours. Further disaggregating the sample by national origin and type of racial admixture would be useful adjuncts to these analyses but should not replace these categories.