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Immunologic phenomena in experimental rodentiosis. I. Development of delayed skin reactions and peritoneal macrophage migration inhibition in guinea pigs infected with Yersinia pseudotuberculosis.

Hypersensitivity in guinea pigs infected with Yersinia pseudotuberculosis was studied by means of skin tests and the migration inhibition test using peritoneal macrophages. Delayed hypersensitivity developed in the course of rodentiosis. Intensity of delayed skin reactions and degree of migration inhibition of peritoneal macrophages in the presence of specific antigen were strictly correlated.