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Lognormal Distribution of HBsAg Strengths in an English Population

Abstract. The frequency distribution of reverse passive haemagglutination titres for HBsAg in the sera of 78 positive blood donors found during a 2.5–year period closely follows a lognormal distribution curve. This lognormal distribution suggests that the total population of HBsAg‐positive donors during this period was approximately 84. The modified Hepatest now in use will be expected to detect 82 of these, and to miss only 1 HBsAg‐positive donor in 50,000 screening tests of Manchester blood donors.