{'fraction_non_alphanumeric': 0.02119460500963391, 'fraction_numerical': 0.005780346820809248, 'mean_word_length': 6.222222222222222, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Lipoamide or lipoic acid stimulates mitochondrial biogenesis in 3T3‐L1 adipocytes via the endothelial NO synthase‐cGMP‐protein kinase G signalling pathway

BACKGROUND AND PURPOSE Metabolic dysfunction due to loss of mitochondria plays an important role in diabetes, and stimulation of mitochondrial biogenesis by anti‐diabetic drugs improves mitochondrial function. In a search for potent stimulators of mitochondrial biogenesis, we examined the effects and mechanisms of lipoamide and α‐lipoic acid (LA) in adipocytes.