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Normal clinical chemical values for pregnant women at term.

Results for clinical chemical determinations on serum of 20 to 39-year-old pregnant women at term were compared (SMA 12/60) with those for nonpregnant women in the same age group. Sera from the pregnant group had higher mean uric acid and cholesterol concentrations; higher mean alkaline phosphatase, lactic dehydrogenase, and glutamic oxaloacetic transaminase activities; and lower mean glucose, urea nitrogen, protein, and albumin concentrations. All differences are significant (P <0.001). Phosphorus and bilirubin concentrations did not differ significantly for the two groups. The increase in alkaline phosphatase activity in the pregnant group is evidently due to a heat-stable fraction, which does not correlate (at term) with number of weeks gestation, infant sex, infant weight, or placental weight. Forty women who had high concentrations of serum uric acid showed no signs of toxemia of pregnancy and delivered normal infants.