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A functional localizer for identifying brain regions engaged in prosodic processing in individual subjects

Prosody is an important cue for constraining interpretation. Brain imaging methods – fMRI in particular – have the potential to shed light on the mechanisms that support prosodic processing, but one widespread problem with previous neuroimaging studies of language is that they almost exclusively rely on group-based analyses where brains are aligned in a common space. Due to inter-individual differences in brain anatomy [1-3], functional activations do not line up well, leading to decreased sensitivity and selectivity [4-6]. Furthermore, traditional group analyses make it difficult to establish a cumulative research enterprise because if different patterns of results are obtained across studies, there is no way to determine which results are (more) valid [7].