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Editors' note: WMH and long-term outcomes in ischemic stroke: A systematic review and meta-analysis

Cerebral microvascular ischemic disease is a leading cause of dementia in the adult population. In their meta-analysis of data from more than 70,000 patients with ischemic stroke, Dr. Georgakis and colleagues examined the association between severity of white matter disease on baseline CT or MRI with 4 outcome measures—all-cause dementia, long-term functional impairment, recurrent stroke, or death due to any cause.