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Chronic Stable Angina.

1. What is the most common cause of angina? Angina is the sensation of discomfort experienced during periods of myocardial ischemia or myocardial infarction. It may occur when myocardial oxygen demand exceeds myocardial oxygen supply. Myocardial ischemia and angina are most commonly the result of significant stenosis of one or more coronary arteries. Typically, coronary artery stenosis that is 70% or more of the coronary artery diameter is flow restricting and may cause angina. In patients with chronic stable angina, myocardial ischemia results when myocardial oxygen demand increases, such as during physical exertion. Coronary vasoconstriction, particularly at the site of a preexisting stenosis, can also contribute to myocardial ischemia and produce angina.