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BIOCHEMICAL COMPOSITION OF THE BLOOD OF DOGS ON THE BACKGROUND OF THE INFLUENCE OF INTENSIVE INVASION OF DIROFILARIASIS

Experimentally obtained new data in the study of the biochemical composition of blood of invasive dogs on the background of the influence of intensive invasion of dirofilariоsis. Biochemical blood tests were performed on 20 dogs intensively infected with microfilaria pathogens of dirofilariasis using standard methods. In the morning, blood from dogs was taken from the forearm vein in test tubes with an anticoagulant for a general blood test, in test tubes with a clotting activator – for biochemical studies. For the study were formed 2 groups: experimental and control. The experimental group (n = 10) consisted of dogs that had microfilariae of dirofilariоsis pathogens in blood samples. A control group of dogs (n = 10) was formed from nonhelminthic animals. Intensive dirofilariasis invasion has a pathological effect on the biochemical blood parameters of dogs in the form of an increase in total whey protein by 28.83 g / l, and enzymes: AST by 27.89 units / l and ALT 47.95 units / l, total bilirubin in 38.01 μmol / l and urea in 17.07 μmol / l. Against the background of control at high intensity of dirofilariasis invasion in dogs, hyperproteinemia with a multiple increase in the activity of AST and ALT, bilirubin and urea manifest with firmness.