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Clinical significance of human kallikrein 10 gene expression in colorectal cancer and gastric cancer

Background and Aim:  Recent evidence suggests that the human kallikrein 10 (KLK10) gene is differentially regulated in endocrine‐related tumors and has potential as diagnostic and/or prognostic marker; however, KLK10 expression has never been investigated in gastrointestinal cancers. The aims of this study were to demonstrate expression and single nucleotide polymorphisms of KLK10 in colorectal cancer (CRC) and gastric cancer (GC), and to correlate the relative KLK10 expression level with clinicopathological factors of CRC and GC.