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Inductive Heating Property of Superparamagnetic Graphene Nanosheets-Fe3O4 Nanoparticles Hybrid in an AC Magnetic Field for Localized Hyperthermia

The superparamagnetic graphene nanosheets–Fe3O4 nanoparticles (GNs–Fe3O4) hybrid has been successfully prepared via an easy and scalable chemical precipitation method. The inductive heat property of GNs–Fe3O4 hybrid in an alternating current (AC) magnetic field was investigated. The potential of GNs–Fe3O4 hybrid was evaluated for localized hyperthermia treatment of cancers. The GNs–Fe3O4 hybrid exhibits a superparamagnetic behavior, its specific saturation magnetization, Ms is 66.963 emu g-1. After exposed in the AC magnetic field for 1140 sec, the temperature of physiological saline suspension containing GNS–Fe3O4 hybrid were 81 oC. The GNs–Fe3O4 hybrid will be useful as good thermoseeds for localized hyperthermia treatment of cancers.