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Target model of nucleosome particle for track structure calculations and DNA damage modelling.

A non-homogeneous target model of nucleosome particle for track structure calculations and biophysical modelling of radiation-induced DNA damage was developed together with a sampling method for non-homogeneous targets. The model allows one to distinguish energy deposited in the histone core, primary hydration shell and nucleosome DNA. Illustrative results for low energy electrons are presented and compared with results obtained with simpler models of a nucleosome particle.