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News in brief

10.1586/14737175.9.2.151 In a study published online in Nature Genetics, researchers from the Mayo Clinic (FL, USA) have identif ied a genetic variant located on the X chromosome that appears to be associated with an increased risk of Alzheimer’s disease (AD) in women. The researchers carried out a detailed genetic analysis of 844 AD patients and 1255 controls. From the 313,504 single nucleotide polymorphisms (SNPs) investigated, they identified 25 SNPs with the most significant allelic association. These SNPs were then analyzed in another 1547 AD patients and 1209 controls. From this, a particular SNP within the PCDH11X gene, located on the X chromosome, was identified.