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Cytokine Secretion Patterns of NK Cells and Macrophages in Early Human Pregnancy Decidua and Blood: Implications for Suppressor Macrophages in Decidua

Problem:  Local immune modulation has been shown to be of considerable importance for the maintenance of successful pregnancy. We have previously reported the secretion of interferon‐γ (IFN‐γ), interleukin‐4 (IL‐4) and IL‐10 in human decidua from early normal pregnancy. The aim of this study was to investigate the cellular source of cytokine secretion in the decidua, and compare this to secretion patterns in peripheral blood.