{'fraction_non_alphanumeric': 0.02872531418312388, 'fraction_numerical': 0.02244165170556553, 'mean_word_length': 5.597633136094674, 'pattern_counts': {'":': 0, '<': 2, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
[Expression of differentiated embryo-chondrocyte expressed gene l in oral squamous cell carcinoma and its clinical significance].

PURPOSE
To investigate the expression of differentiated embryo-chondrocyte expressed gene l（DEC1）in oral squamous cell carcinoma（OSCC）and its clinical significance.


METHODS
Detection of the protein expression of DEC1 in tissue specimens from 80 primary OSCC patients and 30 cases of normal oral mucosa were performed using immunohistochemistry. SPSS10.0 software package was uses for statistical analysis.


RESULTS
The result of immunohistochemistry showed that positive expression rate of DEC1 in OSCC tissues was 92.50%, 5.00% in normal oral mucosa tissue. The difference was statistically significant (P<0.05). In OSCC tissues, the difference in expression of DEC1 was statistically significant (P<0.05) between highly differentiated group and lowly differentiated group, between patients with lymph node metastasis and patients without lymph node metastasis.


CONCLUSIONS
The significantly increased DEC1 gene may be associated with the tumorigenesis and development of OSCC.