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In non-pregnant patients over the age of 18 with symptomatic bacterial vaginosis, does the addition of oral or vaginal probiotics compared to standard antibiotic use alone, decrease time to recurrence?

Bacterial vaginosis (BV) is the most common cause of symptomatic vaginitis in women of reproductive age, effecting approximately 15 to 50% of cases.1,2 It is caused by alteration of the vaginal flora resulting in a decrease of lactobacilli and a seven-fold increase in concentration of organisms including Gardnerella vaginalis, Mycoplasma hominis and Prevotella spp. that are frequently found in women with normal vaginal flora.1 Risk factors include new or multiple sexual partners, frequent douching and social stressors.1 Complications associated with BV infection include higher risk of pelvic inflammatory disease, premature rupture of membranes in pregnant women and strong association with many sexually transmitted diseases, including HIV, Chlamydia trachomatis and Neisseria gonorrhoeae.2