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Predictive formula of coma onset and prothrombin time to distinguish patients who recover from acute liver injury

Acute liver failure (ALF) is defined as acute liver injury (ALI) associated with coagulopathy. A follow‐up strategy for ALI and characterization of ALI patients with a risk of progressing to ALF have never been established. To establish predictive markers for progression from ALI to ALF, this study compared the clinical characteristics and laboratory data on the day of registration to data from a regional referral system of patients with ALI.