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Three-Dimensional Perspective Display For Chicken Brain Autoradiographs

The glucose metabolism in certain areas of the brain becomes highly active and reflects the degree of the epileptic seizure when evoked. In order to visualize the localization of glucose, C14 labeled glucose is used to produce autoradiographs from brain slices in chicken. The areas having a high concentration of C14 labeled glucose appear darker in the developed film. This paper describes an image processing computer system which displays 3 dimensional perspective views from the brain slice autoradiographs. The series of autoradiographs were digitized by a video frame grabber. The shape of the brain was displayed 3 dimensionally by means of surface contours and the dark areas representing high glucose concentration was embedded in the outlines.