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Long‐term consequences of acute kidney injury during pregnancy

Women with severe preeclampsia and HELLP syndrome (sPE/HELLP) are more likely to develop acute kidney injury (AKI) compared to women without sPE/HELLP. AKI during pregnancy is associated with rates of maternal mortality and fetal loss that range from 30–60%. Women with a history of sPE/HELLP are more likely to develop hypertension, and have higher incidences of chronic kidney disease, end stage renal failure and cognitive failure compared to women with histories of normal pregnancies. We tested the hypothesis sPE/HELLP leads to brain damage during pregnancy which is exacerbated by AKI.