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Highlights from this issue

The observation is similar to that of Ju Lee Oei and colleagues, who report an individual patient data meta-analysis of 3 randomised clinical trials comparing the effects on a composite of death or disability of initial resuscitation with 30% or 60% oxygen for preterm infants born <32 weeks gestation. See pages F437 and F386 Surfactant in late preterm and term infants Viraraghavan Vadakkencherry Ramaswamy and colleagues performed a systematic review and meta-analysis of studies of surfactant therapy for term and late preterm infants with respiratory distress syndrome. Most of the information in these more mature infants was derived from observational studies so there were issues with the level of certainty of the evidence showing that surfactant therapy decreased mortality, air leak, persistent pulmonary hypertension of the newborn, duration of ventilation and of hospital stay.