{'fraction_non_alphanumeric': 0.028554431885782272, 'fraction_numerical': 0.001189767995240928, 'mean_word_length': 5.648221343873518, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Epidemic community-associated methicillin-resistant Staphylococcus aureus: modern times for an ancient pathogen.

Staphylococcus aureus is an important pediatric pathogen causing community-acquired and nosocomial infections. Methicillin-resistant S. aureus (MRSA) isolates were long recognized as health care-associated pathogens (HA-MRSA) found in patients frequenting hospitals and long term care facilities. However, the recent recognition of MRSA infections in healthy children with no risk factors for MRSA signaled that MRSA epidemiology has undergone an important change. New community-associated MRSA (CAMRSA) strains have been responsible for well-recognized S. aureus infectious syndromes such as skin and soft tissue infections and “new” syndromes such as necrotizing pneumonia, necrotizing fasciitis, septic thrombophlebitis and severe sepsis. In the first reports describing CAMRSA isolates, it was recognized that they were less resistant to non-lactam antibiotics than HA-MRSA. Further, CAMRSA clinical syndromes differed from those caused by HA-MRSA and more often resembled community-acquired methicillin-susceptible S. aureus (CAMSSA) disease. What does the term CA-MRSA mean? Definitions have varied. The Centers for Disease Control and Prevention has defined CA-MRSA as an isolate obtained from a patient in the outpatient setting or in the first 48 hours of hospitalization in the absence of identified risk factors for MRSA acquisition. Others have relied on the antibiotic resistance profile, usually referring to clindamycin susceptibility to define CA-MRSA isolates. A molecular definition exploits certain genetic polymorphisms present among MRSA strains.