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T-cell counts and what they mean.


 The blood contains red, oxygen-carrying cells and white, immune-system cells. The T-cell count measures white blood cells, and is determined by multiplying together the following three numbers: 1) the total number of white blood cells; 2) the percentage of white blood cells that are lymphocytes; and 3) the percentage of lymphocytes that are T-helper cells. (Lymphocytes are a specialized kind of white blood cell that tell other immune system cells how to fight infections.) The T-cell count is important because HIV directly infects and damages T-cells, causing the number of T-cells in an HIV-infected person to decrease over time. When HIV disease progresses and the T-cell count drops, the immune system is less able to fight off invading germs. Therefore, the likelihood of contracting an infection, especially an opportunistic infection, increases. Decreasing T-cell counts may encourage the patient to take prophylactic (preventative) medicines in order to counteract the increasing risk of opportunistic infections. T-cell counts may also influence the decision to begin anti-HIV therapy, such as AZT. Although T-cell counts can offer a certain amount of information, they only serve as one measure of the patient's health.
