{'fraction_non_alphanumeric': 0.03152789005658852, 'fraction_numerical': 0.021018593371059015, 'mean_word_length': 5.316326530612245, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Myasthenia gravis in Jamaican children: a 12-year institutional review

Abstract Background: Myasthenia gravis is uncommon in children. The clinical characteristics in children of the English-speaking Caribbean have not been documented previously. Objective: To describe the clinical characteristics and outcome of children with myasthenia gravis at two tertiary hospitals in Jamaica. Methods: The case-notes of all children with a diagnosis of myasthenia gravis managed at the University Hospital of the West Indies and Bustamante Hospital for Children between January 1994 and December 2005 were reviewed. Results: There were 34 children; mean age of onset of illness was 7·5 years and mean period of follow-up was 38·5 months. The male-to-female ratio was 1∶1·3. Nineteen (59%) presented with ocular manifestations; 47% of these developed signs of generalised involvement. Most were treated with pyridostigmine and prednisone. Eight patients had thymectomy. Four patients (12%) entered remission. There were two deaths. Conclusions: Myasthenia gravis in Jamaican children is similar to that in other populations. It is more common in female children. Most children present with ocular manifestations and remission occurs infrequently.