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Change in respiratory syncytial virus seasonality in Finland

RSV (respiratory syncytial virus) is the most frequent cause of lower respiratory tract infection in infants, with a hospitalization rate up to 35 per 1,000 children younger than one year (1). RSV causes bronchiolitis, wheezing bronchitis and bronchopneumonia demanding respiratory support. Altogether 10% of RSV positive hospitalized children need intensive care (2). RSV infection can be severe particularly in preterm infants and infants with severe congenital heart defects. In high-risk children, monthly prophylaxis with monoclonal antibody decreases the severity of RSV illness during the epidemics.