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Organ‐specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium

In the article by Wiles et al. (2004) the wild-type Citrobacter rodentium (and naladixic acid-resistant derivative) strain used was not David Schauer’s DBS100 (Schauer et al., 1993) but ICC168 which is a wild-type strain (formally Citrobacter freundii biotype 4280) obtained from the original stocks of S. Barthold (Barthold et al., 1977). Recent comparisons have highlighted some differences between DBS100 and ICC168. C. rodentium ICC169 is a spontaneous naladixic acid-resistant derivative of C. rodentium ICC168 (Ghaem-Maghami et al., 2001). All luminescent derivatives were made by transposon mutagenesis of C. rodentium ICC169. References