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Pediatric sepsis from start to finish.

“Understanding the true risk of death in an episode of severe sepsis or septic shock in childhood is surprisingly complex.” This conclusion reported by Cvetkovic and colleagues from London (1), nicely summarizes a database investigation that provides new insight into pediatric sepsis epidemiology. Once again, these investigators have ascertained that sepsis (and critical illness in general) begins and ends outside of the confines of the pediatric intensive care unit (PICU) (2).