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Unified quantification of variation in passive knee joint constraint

The interrelationship that exists between multiple degrees of freedom to produce a net constraint across the range of passive motion of the knee is not fully understood. Manual joint laxity assessments were performed on 28 cadaveric specimens and used to develop a unified description of the passive laxity envelope that incorporated multiple degrees of freedom into a single analysis using radial basis functions. The unified envelopes were then included in a principal component analysis to identify the primary modes of variation. The first three modes of variation constituted 82% of the variation. The first principal component (36.5% explained variation) correlated with changes to the relationship between varus–valgus and internal–external rotation and had the largest impact on internal–external laxity. The second principal component (27.2% explained variation) correlated with a shift in the internal–external envelope. The third principal component (18.3% explained variation) correlated with a shift in the varus–valgus envelope and a change in varus–valgus laxity. This research presents a novel methodology for quantifying complex changes to passive knee constraint, which may be used as a means for objectively scoring joint laxity and evaluating complex relationships between degrees of freedom in a single analysis.