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Implications of some genetic control mechanisms in Neurospora

For the would-be writer of a review article, it can be sobering to ask whether the article is needed. On posing this question to myself, I realized that a number of very perceptive and, in some cases, extensive reviews have already appeared in print. These are listed below. I saw few ways to cover the same ground differently, and certainly no way to cover it better. It seemed more profitable to use this space as an opportunity (i) to examine a few of the special features ofNeurospora crassa and closely related species that are likely to escape attention elsewhere and (ii) for some unabashed speculation about the evolutionary pressures that have shaped the control mechanisms extant in Neurospora and perhaps in other eucaryotes. This article is meant to be read with that in mind.