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Effect of a Low Fat Diet Intervention on Blood Pressure and Hypertension: Rather Switch to a Mediterranean Diet?

High blood pressure (BP) and hypertension are major global risk factors for cardiovascular disease 1 and require a holistic approach for optimal management with both nonpharmacological and pharmacological interventions. National US and international recommendations 2–4 for the management of high BP endorse lifestyle changes, including weight loss for the overweight or obese, regular physical activity, adherence to a healthy nutrition plan such as the Dietary Approaches to Stop Hypertension (DASH) diet, 5 and reducing dietary sodium intake. 6 However, which single nutrient or dietary pattern has the most profound effect on BP is a matter of ongoing research. 7