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[Antiviral and anticellular activity of human leukocytic and fibroblastic interferons in homo- and heterologous cells].

Investigations of the antiviral and antiproliferative activities of human alpha and beta interferons were carried out in homologous and heterologous cell cultures (EBTr and TR - human embryo trachea cells). Both interferons were shown to inhibit the cytopathic effect of vesicular stomatitis virus and incorporation of 3H-thymidine in homologous cells. In heterologous cells of bovine embryo trachea the antiviral and antiproliferative effect was observed only with human alpha interferon.