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Gene Prediction , II — DRAFT Feb

Here we discuss a general probabilistic model of gene structure of human genomic sequences recently proposed by Berge and Karlin []. Earlier approaches have focuses on prediction of individual functional elements like promoter regions, splice junctions, coding regions etc. in isolation. This model allows integration of multiple types of information so that the entire gene structure may be predicted. As a case study, we look at a computer program called GENSCAN which uses this model for gene identification.