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Soluble interleukin 2 receptor (sIL‐2R) levels in renal transplant recipients

Abstract:  Background:  Allograft rejection is associated with T cell activation. T cell activation leads to secretion of soluble IL‐2 receptor and elevated serum soluble IL‐2 receptor (sIL‐2R) levels. However, the clinical implication of individual elevated sIL‐2 receptor levels is unclear. We followed levels of sIL‐2R pre‐ and post‐transplantation to determine if sIL‐2R levels predict rejection episodes or degree of graft function.