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Colorectal Adenocarcinoma: Imaging using 5-Fluoracil Nanoparticles Labeled with Technetium 99 Metastable.

Adenocarcinoma of colon and rectum are one of the most common cancers worldwide, responsible for over 1,300,000 people diagnosed. Also, they are responsible for metastasis, which leads to death in less than 5 years. In this study, we developed, characterized and pre-clinically test a new nano-radiopharmaceutical for early and differential detection of adenocarcinoma of colon and rectum. Results demonstrated the specificity of the developed nano system and the ability to reach tumor with very specific targeting. Also the imaging data support the use of this nano-agent as a nano-imaging-guided-radiopharmaceutical.