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A meta-analytic review of the sensitivity of the Wisconsin Card Sorting Test to frontal and lateralized frontal brain damage.

The author conducted 2 meta-analyses on the Wisconsin Card Sorting Test (WCST). The 1st compared participants with frontal lobe damage to those with posterior brain damage, whereas the 2nd compared participants with left and right frontal damage. Effect sizes based on the difference between groups were calculated for WCST variables and a composite measure. Effect sizes for these variables, except nonperseverative errors, indicated significantly poorer performance for participants with frontal damage. There were no significant differences for the left versus right comparisons. Moderator analyses using the composite measure for the frontal versus nonfrontal analyses indicated that the largest effect size was for dorsolateral damage. Though this study indicates that the WCST is sensitive to frontal lobe damage, caveats are discussed.