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Analysis of gold nanoparticles as carriers for different molecular dye type photosensitizers in Photodynamic Therapy applied to carcinomas

The effect of gold nanoparticles on the depth of photodynamic treatment for different types of photosensitizers with significant potential for their application in oncology is studied by means of a predictive model. Results show differences of up to 18 % when nanoparticles are used as carriers for Cyanine based photosensitizers in a carcinoma. Therefore these results could be useful to rule out the administration of this means of delivery for certain molecular dye type photosensitizers when Photodynamic Therapy is applied to carcinomas with a given structure.