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Prophylaxis of Groub B Streptococcal Infection

I wish to comment on the abstract "Neonatal Sepsis," (PIR 1985;6:236). In this abstract of an article by Pyati et al (N Engl J Med 1983;308:1383), R.H.R. quotes accurately that 21/24 cultures taken within 60 minutes of birth were positive (for group B streptococci). In their paper, Pyati et al also stated that 9/21 infants with positive blood cultures were "symptomatic" between zero and four hours after birth. Pyati et al also wrote that the three babies with blood cultures that were initially negative had "repeat cultures between 3 and 70 hours after birth that were positive for group B streptococcus" and "these three infants were symptomatic within four hours after birth." Pyati et al added, "thus most infants were infected before penicillin administration."