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Immune reactivity during SARS-CoV-2 infection and further mitigation measures for COVID-19

: In the wake of the COVID-19 outbreak in 2019, particular attention has been paid to populations often considered immunocompromised -- the elderly, pregnant women, newborns, and children. Therefore, this review aims to study these populations. This study collected the immune characteristics of the above "suspected immunocompromised people" from various sources in the public domain, the body's reaction to being "attacked" by the virus, and the adverse physical effects of the virus on these people. According to the survey, the elderly is more vulnerable to the virus, more difficult to treat, the prognosis is relatively poor; As the immune stage of pregnant women is divided into three stages, each stage has different resistance to the virus, and the risk of infection is different at different stages. Unevenness of vaccines availability has been discussed in this review as it is one of the key factors impacting the trend of the pandemic control negatively. Public health and social measures (PHSM) have been reviewed and its significance in controlling the spread of the disease even after vaccination is discussed.