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Optimal Cytoreduction is an Independent Prognostic Factor in Ovarian Carcinosarcoma: A Turkish Gynecologic Oncology Group Study

78 Ovarian carcinosarcoma (OCS), accounting for only 1-4% of all ovarian malignancies, is a rare neoplasm characterized by sarcomatous and epithelial elements.1-3 Some authors have proposed that OCSs originate from the müllerian epithelium and then differentiation/metaplasia to a sarcomatous structure, supporting the hypothesis that OCS is a metaplastic epithelial carcinoma.4-6 OCS is highly aggressive and has a poor prognosis, presenting with a disease that has spread beyond the ovary in up to 90% of cases at Optimal Cytoreduction is an Independent Prognostic Factor in Ovarian Carcinosarcoma: A Turkish Gynecologic Oncology Group Study