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IMPLICATIONS OF LIMITATION OF RENAL FUNCTION FOR THE NUTRITION OF LOW BIRTHWEIGHT INFANTS

Aperia, A, Broberger, O. and Zetterström, R. (Departments of Paediatrics, S:t Görans's Hospital and Huddinge Hospital, Stockholm, Sweden). Implications of limitation of renal function for the nutrition of low birthweight infants. Acta Paediatr Scand, Suppl. 296:48, 1982. — Renal function is immature in low‐birth‐weight infants. The glomerular filtration rate is low during the entire first month of life. It is 20–50% of that observed in older children and adults. This limits the excretory capacity of the kidney and might set an upper limit for the protein intake. The capacity to reabsorb bicarbonate is not fully developed. This predisposes the low‐birth‐weight infant to metabolic acidosis. The capacities to excrete sodium when in positive sodium balance and to retain sodium when in negative sodium balance are limited. If the daily sodium balance is not well monitored, conditions of negative sodium balance with hyponatremia as well as of positive sodium balance with hypernatremia might occur.