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Formulation of a ginger extract liquid bandage and in-vitro assessment of physical and chemical characteristics

The aim of the present study was to design a liquid bandage containing ginger extract and to evaluate its physical and chemical characteristics. The liquid bandage containing Ginger extract (LBGE) was formulated and its physico-chemical characterization was carried out. Physical characteristics like pH, viscosity, drying time, surface morphology and chemical characteristics like drug release at different time intervals were assessed. Surface morphology was carried out using Scanning Electron Microscopy (SEM) and drug release studies were assessed using High Performance Liquid Chromatography (HPLC).The results showed that pH of formulated LBGE was 6, drying time was 55seconds and viscosity was 6cps at 30rpm. SEM images indicated a smooth and uniform spray pattern. The liquid bandage film was found to be intact at the end of 24 hours. Cumulative drug dissolution was found to be 3.67% at the end of 24 hours. Based on the result we can conclude that LBGE possess satisfactory physical characteristics and drug release to provide the therapeutic response.