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[Effects of arginine on properties of the erythrocyte membrane in hypoxia].

The antioxidant effect of arginine evident from stabilization of membrane structure and properties and activation of oxygen-toxicity-protecting enzymes was demonstrated in hypoxia. The intraperitoneal injection of L-arginine-HCl in a dose of 120 mg per 100 g body mass prevented the increase of microviscosity, membrane permeability and lipid peroxidation products level in hypoxia. At the same time the activity of the antioxidant enzymes--superoxide dismutase and catalase--was increased in red blood cells by 64 and 46%, respectively.