{'fraction_non_alphanumeric': 0.024, 'fraction_numerical': 0.015111111111111112, 'mean_word_length': 5.220994475138122, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
In vitro evaluation of the heparin-coated Gyro C1E3 blood pump.

The blood-contacting surface, mainly composed of polycarbonate, of the Gyro C1E3 pump was modified using plasma glow discharge to introduce a carboxyl functional group, coated with a base layer of polyethyleneimine as a linker, and coupled with heparin by multi-ionic binding to enhance blood compatibility. A relative surface content of 3.7% sulfur, which demonstrated heparin immobilization on the polycarbonate substrate, was observed on x-ray photoelectron spectroscopy, and a initial bioactivity of approximately 88.5 +/- 7.3 mIU/cm2 was obtained by the chromogenic method for antifactor Xa assay. Furthermore, in vitro observation of platelet and fibrin adherence using bovine blood under dynamic flow conditions for 6 h revealed that the multi-ionically heparinized Gyro C1E3 had significantly stronger antithrombogenecity than the noncoated original type which was evaluated as a good hemocompatible blood pump for clinical use. Not only the Gyro C1E3 but also the ionically heparin-coated Gyro pump are expected to be thromboresistant in clinical use.