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The Effect of Preoperative Apotel Administration on Postoperative Drug Use in Patients with Inguinal Hernia Surgery

: Background & aim: Proper management and control of pain after surgery is one of the major concerns of physicians and patients that requires evaluation and treatment based on observation of the patient's condition. Considering the importance of analgesia in patients after inguinal hernia surgery, the aim of the present study was to determine the effect of preoperative apoptosis on the rate of drug use after inguinal hernia surgery. Methods: In the present single-blind clinical trial study conducted in 2017, 100 patients with inguinal hernia were randomly divided into two groups: Apotel and placebo. The case group received 15 mg / kg Apotel body weight half an hour before the operation and the control group received a placebo. The amount of pain and the need for analgesia were measured according to the criteria of the visual scale at intervals of 1, 2, 4, 8, 12 and 24 hours after surgery and were recorded in a questionnaire that is specific to each patient. Postoperative analgesia was prescribed based on the patient's request and the severity of the pain. The scale of pain retention scale was used to determine the pain score of patients after surgery. The collected data were analyzed using SPSS software version 15 and statistical tests of t-test, independent t-test, Mann-Whitney and Friedman. Results: The mean age of patients in the control group was 46.00 32 7.32 years and in the case group was 45.52 7 7.10 years. The amount of pain and need for drugs at 1, 2 and 4 hours after surgery in the target group was significantly lower (p <0.001). At 8, 12 and 24 hours, there was no significant difference in pain between the two groups (p = 0.48), but the need for drugs in the target group was significantly lower (p <0.001). Conclusion: According to the results, Apotel is effective in reducing postoperative hernia pain, increasing the duration of postoperative analgesia and reducing the use of drugs. Therefore, it can be used as a suitable and available alternative to narcotics in pain relief after surgery.