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Spectral Analysis of Physiological Signals

This paper examines the cross-correlation, power spectral density (PSD), transfer function estimation, and coherence between intracranial pressure (ICP) and arterial blood pressure (ABP). 300 second segments are used for the spectral analysis. Using the techniques mentioned we hope to find precursors to spikes in ICP. An inference is made that a decrease in heart rate may be one precursor. An unknown frequency shows up in PSD plot and in the coherence plot. We conclude that the transfer function provides very little insight. Index Terms Intracranial Pressure, Traumatic Brain Injury, Arterial Blood Pressure, Cross-correlation, Transfer function estimation, Power Spectral Density, Ergodicity, Stationarity.