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Use of magnetization transfer contrast to improve single breath‐hold three‐dimensional MR‐portography with bolus injection of gadopentetate dimeglumine: A preliminary report

We investigated whether better visualization of the intrahepatic portal system could be obtained by adding magnetization transfer contrast (MTC) to three‐dimensional MR portography (3D‐MRP). In 15 healthy volunteers, 3D fast low‐angle shot images combined with an off‐resonance pulse were obtained after bolus injection of gadopentetate dimeglumine during one period of breath‐holding. Within 1 week after injection, MR images without MTC were obtained using the same scanning condition. MRPs with and without the MTC pulse were compared quantitatively and qualitatively. The contrast‐to‐noise ratio of the portal vein–liver was significantly higher in the group imaged with the addition of MTC. Qualitatively, the use of MTC improved peripheral portal branch depiction on maximum‐intensity projection images. Even when the MTC pulse was added to the conventional method of 3D data collection, it was possible to obtain images within one period of breath‐holding. In conclusion, the use of MTC can substantially enhance the quality of 3D‐MRPs.