{'fraction_non_alphanumeric': 0.03305785123966942, 'fraction_numerical': 0.01589319771137953, 'mean_word_length': 5.221343873517786, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Multiple Sclerosis: A New Hypothesis

"Despite a continuing advance in knowledge concerning many aspects of multiple sclerosis and the existence of several not entirely implausible aetiological theories, a number of experienced workers in this field have professed that they would not be too surprised if the final answer to the questions of causation and pathogenesis in multiple sclerosis involved entirely novel or hitherto unsuspected disease processes" [I]. Multiple sclerosis, as a clinical and pathological entity, was first described by Cruveilhier [2] and Carswell [3]. The term, "sclerose en plaques," appeared in the literature in 1866 in a report by Vulpian, in which two cases were described by Charcot [4]. Charcot called attention to mild cases and formes frustes, but further description of the disease —including the triad of nystagmus, scanning speech, and intention tremor—is also attributed to him [5-7]. Many different etiologies have been suggested for multiple sclerosis. A prominent consideration has been an infectious origin of the disease. In 1884, Marie stated that it might be a complication of a number of infectious illnesses [8]. Charcot suggested a relationship to an antecedent illness and cited cases that had followed cholera, smallpox, and typhoid fever. Bullock, in 1913 [9], and Gye, in 1921 [10], claimed to have transmitted multiple sclerosis from man to rabbits, using cerebrospinal fluid injections. In these and other such studies, the failure to identify a specific organism has been a stumbling block. Pette has pointed out the