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The Postanesthetic Antiemetic Effect of Premedication with Dehydrobenzperidol Before Ether Anesthesia

A study was performed to evaluate the antiemetic effects after ether anesthesia when dehydrobenzperidol (DHB) and pentobarbital were used for premedication and to compare these effects with halothane anesthesia when pentobarbital was used as premedication. Eighty‐four patients undergoing minor surgical operations were randomly divided into three groups. The patients received ether and either DHB 0.2 mg/kg or pentobarbital 2 mg/kg for premedication, or halothane and pentobarbital 2 mg/kg for premedication. The complaints of nausea and vomiting were recorded 24 h after anesthesia. We found that DHB compared to pentobarbital had a greater antiemetic effect after ether anesthesia, but the difference was not significant (P > 0.05). However, if only persistent nausea and vomiting were considered, the difference was significant (P < 0.05). The incidence of nauseal/vomiting after ether anesthesia with DHB as premedication was a little higher compared to halothane anesthesia with pentobarbital as premedication, but the difference was not significant (P > 0.05). However, if only persistent nausea/vomiting was considered, the incidence of complaints was equal in the two groups.