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Multiple telangiectasiae in a woman positive for hepatitis C virus

A 65-year-old woman was referred for evaluation of telangiectatic macules that had been present for about 4 years. On physical examination, asymptomatic, blanchable, bilateral and symmetrical telangiectatic macules were seen (Fig. 1). The lesions had first appeared on the proximal thighs and extended progressively throughout both legs and, to a minor extent, on both arms. Darier sign was negative. The oral mucosa and nail beds were not affected, and the patient was asymptomatic. The patient had a history of hypertension and chronic hepatitis C virus (HCV) diagnosed in her youth, which had not required treatment. There was no personal or family history of bleeding diathesis, and she denied the use of any new drugs. Laboratory studies, including complete blood cell count, coagulation tests, levels of antinuclear antibodies, double-stranded DNA, rheumatoid factor, C3, C4, tryptase and C-reactive protein, erythrocyte sedimentation rate, and serology testing for human immunodeficiency virus (HIV) and hepatitis B, were all normal or negative.