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Pandemic-Related Submissions: The Challenge of Discerning Signal Amidst Noise.

The emergence of a novel coronavirus in the final quarter of 2019 precipitated a public health emergency on a global scale. The SARS-CoV-2 virus pandemic, and the spectrum of clinical illnesses labelled COVID-19, has led to more than 6.6. million confirmed cases and more than 390,000 deaths worldwide as of June 5, 2020. More than 1.8 million cases and more than 108,000 attributable deaths have occurred in the United States of America, where this journal is published. This pandemic has also given rise to unprecedented global efforts to describe the pathogen and its mode of spread, the pathobiology of infection and response, and the medical countermeasures that might be undertaken. These include the development of antiviral drugs, antibody treatments aimed at neutralizing the virus, treatments aimed at mitigating the host response, and supportive therapies intended to prevent or attenuate the multisystem complications of the disease. Medical journals, including Critical Care Medicine, have played important roles in reviewing, and ultimately publishing those efforts: since the first report of the pandemic, Critical Care Medicine has received more than 400 original submissions with titles containing either “SARS”, “Coronavirus”, or “COVID”. Many more informal inquiries were either redirected to our sister journal, Critical Care Explorations, or led to our advising the authors not to submit to either journal. The challenges to ourselves, to our readers, and to the world communities have been to discern data from anecdote, information from observation, and ultimately signal amidst noise.