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Serum Haptoglobin in Patients with Ovarian Malignancies

Sera from 58 patients with ovarian cancers were typed and quantified for haptoglobin levels. In 35 of these patients, serial haptoglobin determinations were made. The relationships between haptoglobin type and tumor type, mucin production and the degree of differentiation were investigated. The relationships between haptoglobin level and tumor type, amount of tumor, death from tumor, mucin production, degree of differentiation, and recent radio-, chemo- and surgical therapy were also studied. The results and conclusions indicate that serial serum haptoglobin determinations may be of clinical value in following the course of malignant ovarian tumors, and in suggesting tumor recurrence before it is physically or radiologically evident.