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The learning ability and motility of senescence accelerated mice (SAM‐P/1) treated with Toki‐Shakuyaku‐San

The effects of the Kampo medicine Toki‐Shakuyaku‐San on the motility and learning ability of mice were studied. An assay on mice aged 5 months after 15 weeks of administration revealed no change in spontaneous motility. However, in a study on learning ability employing passive avoidance task, the latent periods of test trial were significantly longer in the Toki‐Shakuyaku‐San administered group than in a control group, indicating that Toki‐Shakuyaku‐San may play some role in the alleviation of learning disturbances in mice.