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Endocrine cell dysplasia (nesidioblastosis): a relatively unrecognized entity in Pakistan?

Nesidioblastosis is quantitative as well as qualitative abnormality of pancreatic endocrine cells. There is scattering of small endocrine cell clusters arranged haphazardly rather than the peripheral location within the lobule. Islet contours are irregular, tailing off into parenchyma. These islets are present in intimate association with ducts forming ductuloinsular complexes We recently encountered a new born baby with signs and symptoms of endocrine cell dysplasia.