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Preliminary Report Peritoneal protein loss in children with nephrotic syndrome during peritoneal dialysis

Background. The passage of proteins across the glomerular ﬁltration barrier is mainly determined by the size of the protein. In nephrotic syndrome (NS) the glomerular permselectivity is a V ected, causing pro-Introduction teinuria. Some authors suggest the existence of a generalized basement membrane defect. The permeability characteristics of the peritoneal basement mem-In the normal situation the human glomerular ﬁlter brane in children with NS are not known. Methods. The of proteins MW