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Pharmaceutical care for patients with diabetes: storage of insulin

According to statistics, 1.2 million Ukrainians suffer from diabetes, and 201626 people being registered and requiring insulin (PI). In Ukraine, a system of reimbursement is introduced, which provides for the dispatch of PI from pharmacies. Thus, in the process of providing patients with diabetes with insulin, pharmacies play a significant role and, accordingly, provide them with pharmaceutical assistance. Insulin is used to treat both type 1 and type 2 diabetes mellitus. Successful treatment requires confidence that the insulin will work properly. Improper storage can lead to a decrease in insulin activity, which will affect its ability to effectively and predictably control the patient's blood sugar. It is important to provide the patient with correct recommendations for storing insulin when dispensed from the pharmacy. 
The purpose of the work was to develop practical recommendations for pharmacy workers and patients with diabetes mellitus regarding the storage of PI. 
The objects of study were electronic and paper sources of information, Instructions for the use of PI. Content analysis and methods of bibliosemantic, marketing, generalization analyzes were applied. 
Marketing research of PIs whose names are subject to reimbursement on dispensing from pharmacies showed that the number of trade names is 33 names, and taking into account the dosage form – 71. In the bottles are represented 39.4% of drugs, in cartridges – 33.8% and in pre-filled syringes pens – 26.8%. PIs are supplied to the Ukrainian pharmaceutical market by domestic manufacturers, foreign companies and joint ventures. In this case, PIs in bottles are manufactured mainly by domestic manufacturers (16 preparations), cartridge forms – mainly by foreign companies (14 preparations), and pre-filled syringe pens – only by foreign companies (19 preparations). The joint ventures produce only 7 items in vials and cartridges. 
On the basis of the analysis of documents from different countries, the latest scientific researches and instructions for the use of PI, detailed recommendations have been developed, both for pharmacy workers and for patients with diabetes mellitus, for insulin storage. Attention is drawn to the high risk of exposure to temperature during storage and to the prevention of these risks. The recommendations are developed from the point of view of practical application. Separately formulated tips for storing insulin while traveling. The guidelines are designed to provide pharmaceutical assistance to patients with diabetes at an appropriate level with the release of PI. The issue of proper storage of PIs should be included in the undergraduate and postgraduate training of physicians, nurses, pharmacists and pharmacists. Government agencies should promote a coherent approach to the delivery of medical and pharmaceutical care through the development of national recommendations.