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Pre-exposure prophylaxis as HIV prevention in the UK

Effective antiretroviral therapy has revolutionized the treatment of human immunodeficiency virus (HIV) such that mortality and morbidity rates have fallen dramatically [Public Health England, 2015]. HIV is no longer a terminal illness but a manageable long-term condition and people living with HIV, with access to effective treatment and a fully suppressed virus, can now expect a normal life expectancy and be confident they cannot pass the virus on to others. 
 
Mathematical modelling data suggest that at least 2600 men who have sex with men (MSM) are infected with HIV every year [Public Health England, 2015]. This figure has remained the same for the last decade. This means that despite our best efforts at HIV prevention; promoting condom use, increasing HIV testing and diagnosis rates and ensuring access to effective HIV treatment, we have not been able to ‘turn the tide’ on the HIV epidemic in MSM in the UK.