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Cost‐effectiveness of colorectal cancer screening with computed tomography colonography

Prior cost‐effectiveness models analyzing computed tomography colonography (CTC) screening have assumed that patients with diminutive lesions (≤5 mm) will be referred to optical colonoscopy (OC) for polypectomy. However, consensus guidelines for CTC recommend reporting only polyps measuring ≥6 mm. The purpose of the current study was to assess the potential harms, benefits, and cost‐effectiveness of CTC screening without the reporting of diminutive lesions compared with other screening strategies.