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Calvarial destruction: an unusual manifestation of glioblastoma multiforme.

The typical CT characteristics of glioblastoma multiforme (GBM) are well known . Glioblastomas usually enlarge by infiltrating adjacent brain parenchyma, without affecting the overlying bone. We report an unusual case of a temporal lobe GBM that destroyed the bone of the middle fossa and subsequently infiltrated the temporalis muscle. The presence of bone destruction on CT suggested an extraaxial lesion, but MR imaging was useful in confirming the intraaxiallocation of this neoplasm.