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Basic fibroblast growth factor within endothelial cells during vascularization of the anterior pituitary

Basic fibroblast growth factor (FGF‐2), a potent angiogenic peptide, is known to be present in gonadotropes of the anterior pituitary parenchyma of rats and mice, and has been isolated from endothelial cells of many organs. Its localization within endothelial cells has not been determined, nor the mechanisms by which it might be released from endothelial cells during normal organogenesis.