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A sex-specific prosthesis was not superior to a high-flexion prosthesis in women having total knee replacement.

Intervention: Patients’ bilateral knees were allocated to a cemented Gender Solutions high-flex prosthesis (Zimmer, Warsaw, Indiana) and a cemented NexGen LPS-Flex prosthesis (Zimmer), in random order. A medial parapatellar approach was used in both knees. Bone cuts were made with reference to the posterior condyles, the anteroposterior axis defined by the so-called Whiteside line, and the transepicondylar axis in combination to ensure external rotation of the femoral component. Thorough resection of osteophytes and posterior capsular release was completed to ensure that all knees had a range of movement (range of motion) from full extension until the calf met the posterior aspect of the thigh. Mobilization was started when the patient arrived on the ward, and physiotherapy was started on the first postoperative day and continued with up to 8 group outpatient sessions.