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Local immunosupression as a factor for self-support of pathologic focus

Cellular and humoral factors of immunosupression are largely the derivatives from injuried tissue. Polytrauma is proposed to be accompanied by the changes making special conditions for organism resistance. It is manifested in the induction of cellular supressive reactions and direct synthesis of autoimmune blocking humoral polypeptides and cytokines. Methods of sedative, antiblocking immunotherapy should be elaborated for successful treatment of infectious posttraumatic complications.