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The Possible Deleterious Effects of the Intramyometrial Injection of Hypertonic Urea

Hypertonic urea has been shown to be an effective midtrimester abortifacient. Although safer than hypertonic saline when injected intravascularly, it has not been compared to saline in the case of inadvertent intramyometrial injection. This report document that intramyometrial injection of hypertonic urea will result in the same type of muscle necrosis as that produced by saline.