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Relationship between moderate alcohol consumption and adiponectin and insulin sensitivity in a large heterogeneous population.

In the January issue of Diabetes Care , Sierksma et al. (1) reported that moderate alcohol consumption increased adiponectin serum levels and improved insulin sensitivity in a small group of insulin-resistant middle-aged men using a longitudinal study. This finding prompted us to examine the effect of moderate alcohol consumption on these parameters in our large heterogeneous group of nondiabetic subjects with and without family history of type 2 diabetes (2,3). Subjects with clinically suspected alcohol abuse were excluded from the study. Data on alcohol …