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Microneurographic research on sympathetic nerve responses to environmental stimuli in humans.

The sympathetic nervous system plays an important role to maintain the homeostasis of vital functions in humans against environmental stimuli. Sympathetic nerve responses to environmental stimuli in humans have been assessed conventionally using rather indirect methods by analyzing the responses of effector organs or by measuring the changes in plasma norepinephrine level. Meanwhile, the microneurography technique has enabled us to approach the sympathetic nervous system in humans more directly. By applying this technique, it has become possible to investigate how the human sympathetic nervous system responds to different kinds of environmental stimuli. In this paper, the usefulness of microneurography as a research tool in environmental physiology is shown together with a review of microneurographic findings on sympathetic nerve responses to environmental stimuli in humans.