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FREQUENCY OF THYROID DYSFUNCTION IN CHRONIC KIDNEY DISEASE PATIENTS

Objective: To determine the frequency of thyroid dysfunction in chronic kidney disease patients. Methods: A Cross-sectional Study conducted at Department of Medicine, Bahawal Victoria Hospital, Bahawalpur. Duration of the study was 20 October 2018 to 19 April 2019. Seventy-two patients with chronic kidney disease, 20 to 60 years of age and of both genders were included. Patients with known thyroid disorders or taking medication that can affect thyroid function (dopamine antagonists, antiepileptic, oral contraceptives, lithium, and glucocorticoids) were excluded. Venous blood sample was taken and sent to the laboratory for thyroid function tests. Results: Age of the patients included in this study was from 20 to 60 year and mean age was 41.97 ± 9.76 years. Most of them 42 (58.33%) were between 41 to 60 years of age. Out of 72 patients, 44 (61.11%) were male and 28 (38.89%) were female with male to female ratio of 1.6:1. Mean duration of disease in our study was 5.71 ± 2.50 years. Mean BMI was 27.75 ± 3.01 kg/m2.Thyroid dysfunction was present in 23 (31.94%) patients of chronic kidney disease. Conclusion: Thyroid dysfunction is frequently found in chronic kidney disease patients.