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[Trial treatment of seborrhea and of common acne in females with the ovulation inhibitors].


 Treatment of acne vulgaris and seborrhea in 557 women using Sequens, Metrulene, and ovariostat is described. The ovulation inhibitors were administered as for contraception. Successful results (cure or considerable improvement) were observed in about 80% of the patients treated with Sequens and Metrulene; the failure rate was less than 10%. The less favorable results obtained with ovariostat are apparently due to the lower estrogen dose (75 mcg vs. 80 and 100 mcg for Sequens and Metrulene, respectively), which may be below the therapeutically effective threshold. Side effects, similar to those of contraceptive treatment, were minor. The possible reasons for the high drop-out rate (126/557) are discussed.
