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The Osteoprotegerin - Von Willebrand Factor Complex: Protagonist Or Bystander In Atherothrombosis?

Abstract Two important cardiovascular risk factors, osteoprotegerin and Von Willebrand Factor form complex in endothelial cells and in circulating blood. The pathophysiological role of the complex is unknown. We give a brief review of the relevant literature and confront it with some of our recent findings regarding the OPG-VWF correlation.