{'fraction_non_alphanumeric': 0.010486891385767791, 'fraction_numerical': 0.0052434456928838954, 'mean_word_length': 5.30188679245283, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Can dietary intake of phase 2 protein inducers affect the rising epidemic of diseases such as type 2 diabetes?

I propose that those populations with a long history of agriculture, particularly where survival was dependent upon relatively few food types, were selected for resistance to diseases such as type 2 diabetes. The basis for this resistance is hypothesized to be a higher basal level of ability to scavenge strong oxidants than found in populations whose recent ancestors depended to a great extent on gathering for their subsistence. Specifically, I hypothesize that selective pressures on populations whose ancestors ate a very restricted diet resulted in the development of populations with high basal levels of phase 2 protein gene expression; a consequence of which is that their tissues have a greater ability to cope with oxidative stress. In contrast, populations with a recent ancestry of hunting and gathering are more dependent upon the consumption of dietary phase 2 protein inducers for adequate phase 2 gene expression necessary for maintaining their tissues' abilities to cope with oxidative stress. This hypothesis can be readily tested by examining basal and induced phase 2 protein gene expression in umbilical cord fibroblasts, obtained from infants of different genetic backgrounds, grown in cell culture.