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High Angle Liquid Cell TEM Tomography for In Situ Observation and 3D Reconstruction in Liquid

Liquid-Cell (LC) electron microscopy (EM) is a rapidly emerging field in EM [1]. While 2-D LC observations are very common for inorganic materials and biological systems, studies of molecular moieties in 3-D in the liquid environment are scarce [2, 3] mainly due to very limited available tilt range of the current LC holders (e.g