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IMMUNOLOGICAL CHARACTERISTICS OF THE INFLAMMATORY PROCESS IN THE PULP

The paper presents the immunological characteristics of the pathological process of the tooth pulp of an inflammatory nature. The content of key markers of inflammatory processes was studied: CD-68, which plays a role in the phagocytic activity of tissue macrophages and type 4 collagen - the main component of the basement membrane of epithelial cells, found in the wall of arterial vessels and the intrinsic substance of connective tissue. An increase in the number of macrophages and a significant increase in the expression of type 4 collagen in pulp inflammation were found. It has been shown that the inflammatory reaction in the pulp is characterized by a sufficient immunological potential for the involvement of a complex of periapical and periradicular tissues in the pathological process and its subsequent long-term completion.