{'fraction_non_alphanumeric': 0.058922558922558925, 'fraction_numerical': 0.016835016835016835, 'mean_word_length': 4.5092592592592595, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
AVP(4-8) Enhances PKC and MAPK Activities in SK-N-SH Cells.

AVP(4-8), one of endogenous metabolite of argipressin(AVP) in brain, can enhance learning and memory. To understand further the molecular mechanism of its function, human neuroblastoma SK-N-SH cell line was chosen as a model to study its signal transduction pathway. Radioligand binding assay showed the existence of binding sites for AVP(4-8) on SK-N-SH cells. The activity of PKC and MAPK in SK cells was significantly enhanced by AVP(4-8), and the enhancement of PKC and MAPK was suppressed by ZDC(C)PR, an antagonist of AVP(4-8).