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Analysis of more complex arrhythmias using the tangential components of the cardiac magnetic field

Patients with left ventricular dysfunction are at high risk for sudden death due to ventricular tachyarrhythmias. It is one of the most important issue how to detect high-risk patients and prevent sudden death. An invasive procedure, electrophysiologic study (EPS), is a “gold standard” in the diagnosis of arrhythmia. Although EPS-guided therapy had been expected to be better than empiric therapy [1], recent study reported that implantable cardioverter-defibrillators reduced the risk of sudden death, but EPS-guided anti-arrhythmic therapy did not [2]. Another reported that EPS suggested negative predictive value of sudden death [3]. It is contradictious whether repetitive EPS could reduce sudden death. The aim of our studies is to improve noninvase magnetocardiograms (MCGs) so that they could replace diagnostic EPS as the gold standard. If radiofrequency catheter ablation (CA) is indicated, an invasive mapping is necessary. If CA is not indicated, a noninvasive diagnostic procedure would be better. We thus developed a magnetoanatomical mapping system and a beat-to-beat analysis by using the tangential components of the cardiac magnetic field. This paper is an outline of our studies.