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A follow up study of contingent negative variation of schizophrenics

Objective To investigate the contingent negative variation (CNV) of schizophrenics in episodic and remitted state. Methods The CNV was recorded with a CA 1000 model instrument from 31 episodic schizophrenics, and 25 of them were retested when their clinical symptoms remitted. Results The episodic patients showed significantly longer A latency( P 0.01) and PINV latency ( P 0.05), and smaller A S 2′area ( P 0.05), as compared with normal control. The remitted patients presented steady CNV wave, shorter A latency ( P 0.05), and higher B amplitude ( P 0.05), as compared with their episodic state. Conclusion It is suggested that the variations of CNV are the state marker of schizophrenia.