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Variance analysis of amino acid in urine among different ethic groups with type 2 diabetes in Xinjiang

Objective To investigate the difference among the urine amino acid in different ethnics of the Han,Uygur,and others with type 2diabetes in Xinjiang. Methods The determination was performed on HPLC with mobile phases of methanol- acetate-H2 O and sodium acetate buffer( p H 6. 5). The content of amino acid were tested by fluorescence detector. Results The levels of aspartic acid,glutamic acid,valine,glycine,phenylalanine,leucine and isoleucine were higher in Han group than those in Uygur group( P 0. 05),and leucine and isoleucine was higher in Han group than those in other ethnic groups( P 0. 05). But the content of proline and cystine was lower than those in other ethnic groups in urine( P 0. 05). Conclusion There were significant differences in amino acid levels in the urine of type 2 diabetes patients among Han,Uygur and other ethnics in Xinjiang.