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[Nasal extranodal NK/T cell lymphoma: terminologic evaluation and diagnostic problems].

OBJECTIVE
To review on the evolution in the understanding of midline destructive lesions of the sinonasal tract in different period, and to describe the clinical features and diagnostic problems on the nasal extranodal NK/T cell lymphoma (NENKTCL).


METHOD
To retrospectively study the nasal CT scannings and the results of serum ANCA of 10 patients with typical clinical characteristics.


RESULT
All patients presented with the symptoms of the nasal obstruction and the nasal discharge. Epistaxis and facial swelling were in the clinical spectrum. Nasal endoscopy and CT scan of paranasal sinuses showed destructive sinonasal lesions. Ten patients were finally diagnosed as having NENKTCL by the pathologic findings combined with immunohistochemical phenotyping. Clinically, Nasal lesions in the cases were similar to those from historical nomenclature.


CONCLUSION
Outdated terminology referring to midline lesions includes a variety of diseases, and NENKTCL is an independent disease focusing on destructive lesions of face and nose.