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A CONTROLLED TRIAL OF ANTICOAGULANTS IN CADAVERIC RENAL TRANSPLANTATION

SUMMARY A controlled trial of 6 months of treatment with warfarin was performed in 59 recipients of cadaveric renal transplants. Twenty-nine patients were allocated the drug and 30 acted as controls. Nineteen of the warfarin group and 20 of the control group had functioning grafts at the end of the trial. Because of complications and contraindications only 10 patients were still taking the anticoagulants at 6 months. There was no difference in renal function between the treated and control patients. Warfarin is of no value to the recipient of a cadaveric renal transplant.