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Mathematical Modelling of Controlled Drug Delivery through Cylindrical Device Consisting Disks

The main objective of the development of drug delivery devices is to successfully deliver the drug to the desired sites of therapeutic action while reducing adverse side effects. In this paper, mathematical models have been developed for controlled drug delivery from cylindrical shaped devices consisting of disks, which is covered by erodible polymer and membrane. The use of polymers is necessary to provide controlled long term delivery of drugs. These implants need not be removed after drug delivery from the body because these are erodible. A model is presented for delivered of the drug from the device to the body. This model provides design of drug delivery device for eroding tumour or chemotherapy to cancerous regions and many such diseases. The results have been obtained for steady state release time and life time of the device. It has been observed that life time increases by adjusting some parameters.