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Marginal zone lymphoma presenting as macrocheilia

Persistent macrocheilia can be caused by a plethora of local and systemic diseases, including granulomatous disorders. We report a patient with lip enlargement due to specific infiltrates of marginal zone lymphoma (MZL). An 82-year-old Caucasian man presented with a three-months history of progressive and persistent swelling of the upper and lower lips with burning sensation, weight loss of 8 kg, and fatigue. This article is protected by copyright. All rights reserved.