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Confocal reflectance imaging of folliculitis in vivo: correlation with routine histology

Near‐infrared confocal reflectance microscopy (CM) is a high‐resolution non‐invasive imaging technique with promising future in dermatology. A pustular lesion from a 35‐year‐old male with a known history of folliculitis was non‐invasively viewed with CM and later biopsied. Optical sections were correlated with routine histology, This optical technique allows us to view non‐invasively transverse skin sections to a conirolled depth in real time. In the CM images, tissue can be visualized with cellular and subeellular detail as shown by imaging infiltrating neutrophils (PMNs) within the subcorneal pustule of a superficial folliculitis in vivo.