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Muscle morphology with special reference to muscle strength in post-polio subjects.

The main histopathologic finding is large grouping of type I and type II fibers. Subjects with low muscle strength had a large number of type I fibers. Large fibers were found especially in men with low muscle strength. The oxidative enzymatic activity was reduced. The findings suggest a compensatory process, with an increased number of type I fibers in subjects, a large reduction in muscle strength, and also an increase in the fiber size. There is a sex difference in the fiber hypertrophy.