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The role of electrochemotherapy in dermal metastases

We thank our learned colleagues, Campana and Gehl , for drawing our attention to the promising results on the management of skin metastases using electrochemotherapy (ECT). The primary focus of our paper was to review the role of surgical excision in cutaneous metastasis in breast cancer patients. Given the wide range of nonsurgical treatment modalities available, we thought it would be helpful and interesting for the reader, to include an overview of these. Unfortunately, given the broad scope of our systematic review, we were unable to provide a “ deep dive ” into one particular modality. Furthermore, we were limited to the number of references we could include, whilst keeping to the guidelines of the journal. We therefore intentionally tried to focus on skin metastases arising in breast cancer patients. For example, the paper by Spratt et al., was a meta ‐ analysis on skin ‐ directed therapies in dermal metastases of any primary malignancy. This included breast cancer, metastatic melanoma, unspecified sarcoma, Kaposi's sarcoma, mucosal squamous cell carcinoma of head and neck, and others. 1 We would like to thank Campana and Gehl for their positive feedback on our paper and humbly suggest that they might consider their own publication focusing on ECT management on cutaneous metastases. This would further highlight the high response rate in these patients and allow cancer centers worldwide to consider making this a more mainstream method of treatment.