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Prospects for Assessment of the Effects of Electrical Injury by Magnetic Resonance a

Magnetic resonance (MR) methods allow noninvasive studies of tissue anatomy, blood flow, and metabolism, with high spatial resolution. Therefore, MR methods may be useful for noninvasive assessment of the effects of electrical shock on living tissue and on the response of tissue to therapy. Serial studies of a single experimental animal can be performed before and after an injury and throughout the entire course of therapy. Such studies would allow the correlation of physiological and metabolic changes during therapy with the ultimate therapeutic outcome. MR methods that are developed using model systems may eventually be used to guide treatment of patients. A wide variety of MR methods can be applied to the study of effects of electrical injury. Examples of applications of these methods to study tissue pathology are described below and possible applications to the problem of electrical injury are discussed.