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Increased diarrhoeal and respiratory morbidity in association with zinc deficiency—a preliminary report

Plasma zinc levels, in a cohort of 116 children aged 12–59 months recently recovered from an episode of acute diarrhoea attending a community health clinic in an urban slum, were related to diarrhoeal and respiratory morbidity in the 3 month period following recovery. Children with low plasma zinc levels (< 60 μg dl−1) spent a significantly greater number of days with watery diarrhoea (rate ratio 1.69 (95% confidence intervals 1.03‐2.78)), diarrhoea associated with fever (rate ratio 1.88 (95% confidence intervals 1.05‐3.34)), and acute lower respiratory tract infections (rate ratio 2.69 (95% confidence intervals 1.64‐4.38)).