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A Study of Clinical Evaluation and Management of Multinodular Goiter

Patients and Methods: A study of 40 consecutive cases histopathologically diagnosed as MNG was made over a period of 1 year from April 2011 to March 2012. Information about the clinical presentation, treatment modality and presence or absence of malignancy was collected in a proforma and was analyzed. Statistical tests employed are tests of proportion, tests of percentage, Student’s t-test and Fisher’s exact test. A P < 0.05 was considered signifi cant. Results: MNG is a common disorder accounting for one-third of all thyroid cases admitted at Karnataka Institute of Medical Sciences, Hubli, during the study period. The common presentation was a female in fourth decade of life with swelling in front of the neck for 4 years duration. Thyrotoxicity was present in 20% of cases and thyroid malignancy was present in 5% cases. The most common procedure performed was total thyroidectomy for non-toxic goiter and sub-total thyroidectomy for toxic goiters. Conclusions: MNG is mostly benign and asymptomatic but may cause concern when it creates compressive symptoms, develop toxicity and rarely becomes malignant. Total thyroidectomy is the predominant treatment modality.