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Non‐transferrin‐bound iron in untreated and ribavirin‐treated chronic hepatitis C patients

Background : In patients with chronic hepatitis C, elevations in serum iron levels, hepatic iron content and oxidative stress‐related molecules have been reported. Treatment with ribavirin induces an increase in hepatic iron concentration. In situations of iron overload, non‐transferrin‐bound iron can appear. Therefore, we determined non‐transferrin‐bound iron levels in untreated chronic hepatitis C patients and in patients during interferon–ribavirin treatment.