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rs-EPI for prostate DWI.

OBJECTIVES
We aimed to investigate if the use of read-out segmented echo planar imaging with additional two-dimensional navigator correction (RESOLVE) for acquiring prostate diffusion weighted imaging (DWI) improves image quality, compared to single-shot echo planar imaging (ss-EPI).


METHODS:
This IRB-approved, HIPAA-compliant study cohort included 162 consecutive males with suspected prostate cancer, who underwent 3 Tesla multiparametric MRI (3T-mpMRI). Two abdominal radiologists, blinded to clinical information, separately reviewed each 3T-mpMRI study to score geometrical distortion, volume of rectal gas, lesion conspicuity and anatomic details delineation first on ss-EPI and subsequently RESOLVE images using five-point scales (1 = excellent, 5 = poor).


RESULTS
There was good-to-excellent inter reader agreement for scoring image quality parameters on both ss-EPI and RESOLVE. Geometrical distortion scores > 3 was seen in 12.3% (20/162) of ss-EPI images, with all having geometrical distortion score <3 on RESOLVE (p < .001). Mean image distortion score was significantly less on RESOLVE than ss-EPI (1.16 vs 1.61, p < .01 regardless of rectal gas, p.05 when stratified by volume of rectal gas degree). RESOLVE was superior to ss-EPI for lesion conspicuity (mean 1.35 vs 1.53, p:.002) and anatomic delineation (2.60 vs 2.68, p:.001).


CONCLUSION
Compared to conventional ss-EPI, the use of RESOLVE for acquisition of prostate DWI resulted in significantly enhanced image quality and reduced geometrical distortion.


ADVANCES IN KNOWLEDGE
Readout segmented-EPI could be an alternative or replacement of single shot-EPI for acquiring prostate diffusion-weighted imaging with significantly less geometrical distortion and significantly improved lesion conspicuity and anatomic delineation.