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Notes from the Journals

Interindividual variations in metabolism of soy isoflavones and lignans: influence of habitual diet on equol production by the gut microflora Rowland IR, Wiseman H, Sanders TA, et al. Nutr Cancer 2000; 3: 27-32 The soy isoflavones are metabolised extensively by the intestinal microflora. There is considerable evidence that there is extensive interindividual variation in isoflavone metabolism. This study looked at diets containing soy, low or high in isoflavones. The amount of dietary fat intake plus the amount of non-refined carbohydrate in the diet controls the capacity of gut microbial flora to synthesise equol. Maximum benefit from soy consumption is obtained with a low-fat, high carbohydrate diet. Literature review