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Argon plasma coagulation for blue rubber bleb nevus syndrome in a female infant.

We report on the case of an 8-month-old baby with blue rubber bleb nevus syndrome (BRBNS) presenting with recurrent bleeding from multiple haemangiomas in the colon and rectum. Treatment with Argon plasma coagulation resulted in long-term success. Our case is unique in that 1) it is the first documented case treated by argon plasma coagulation; 2) it is only the second case in the world literature with involvement of the genital tract; 3) it is the youngest patient treated endoscopically to date; 4) it is the endoscopically treated case with the longest follow-up; 5) it represents the second case of BRBNS reported from this part of the world; and 6) it expands the spectrum of mucosal lesions amenable to this new form of treatment. Argon plasma coagulation is a simple, inexpensive and effective treatment for selected lesions in BRBNS.