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Effect of Structure on Biological Tolerance Comparison of Triiodobenzene Derivatives

Gries H, Mützel W. Effect of structure on biological tolerance: comparison of triiodobenzene derivatives. Invest Radiol 1988;23 (Suppl 1):S97‐S100. Synthesis of basic structures of contrast media is reviewed. Biological tolerance of ionic and nonionic derivatives of triiodobenzene are related to the degree of withdrawal of electrons from their aromatic systems.