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Investigation of class I integron presence and subsequent variable region characterization of 15 clinical isolates from Buenos Aires, Argentina

The aim of this study was to detect class I integron presence and characterize variable regions in 15 clinical isolates from Buenos Aires. Through PCR amplification of 15 isolates of various Enterobacteriaceae, 60% (9/15) were positive for the class I integron structure. NCBI Blast sequencing of 38 sequences revealed that 26% (10/38) contained a segment encoding the aac(6′)‐Ib and 21% (8/38) frequency of occurrence for the aadA1 gene cassette. Several studies have concluded that integron bearing isolates have a significant association with multi‐resistance and this conclusion is supported by our findings.