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A new method for monitoring hydration at high altitude by bioimpedance analysis.

Our study evaluated the performance of a graphical method for monitoring the fluid variation at high altitude in seven adult Caucasian male subjects (average age 25 yr, average height 177 cm). The graphical approach is called the Resistance-Reactance (RXc) graph method and is based on standard bioimpedance analysis (tetrapolar, 50 kHz frequency). Measurements were taken at sea level before the expedition, at 5050 m after 1 wk and 3 wk, and again at sea level after descent. Plasma and urine electrolytes, osmolalities, and the free-water clearance were determined by standard methods. All climbers had baseline impedance vectors within the reference 95% tolerance ellipse for the Italian male population. The high altitude dehydration caused a significant lengthening of vectors, which after descent underwent a significant shortening and returned close to the baseline values. Average urine volume increased by 1.4 l.d-1 in the first week and average body weight decreased by 4.4 kg after 3 wk. The RXc graph method could be useful in the planning of the individual climber's appropriate dehydration and fluid intake at altitude since a feedback control of the hydration is allowed without any assumption of body composition.