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A Health Survey of Gastroenterologist Prescribing Practices with Adalimumab for Crohn's Disease: P‐57

ied in minority populations, especially Hispanics. We developed a communitybased IBD registry for Community Regional Medical Center in Fresno, CA, the region’s safety net health system for a unique population with 50.9% of county residents identifying themselves as Hispanic. We examined potential differences in gender, IBD subtype, disease location, disease behavior, IBD related surgery, and age of diagnosis for this ethnically and socio-demographically diverse population. METHODS: A total of 1,216 possible IBD patients between years 2000 and 2010 were identified by ICD-9 codes from our medical records database. The medical records of all these patients were retrospectively reviewed to confirm diagnosis of IBD and collect epidemiologic and disease specific data. A confirmed IBD case was defined by presence of endoscopic, histologic, or radiographic evidence of IBD and treatment with an IBD-related medication or surgery. This data was analyzed to determine whether there were significant associations between race/ethnicity (Hispanics, Non-Hispanic Whites, Others) and gender, IBD subtype, disease location, disease behavior, IBD related surgery, or age of diagnosis. Chi square analysis was performed for categorical data and all p-values are two-sided. RESULTS: In this period from 2000-2010, there were 614 confirmed IBD cases: 388 ulcerative colitis (UC), 226 Crohn’s disease (CD). Hispanics comprised 39% of UC patients and 16% of CD patients. Among patients with UC, the median age of diagnosis in Hispanics was 32 years, which was significantly younger than in NonHispanic Whites with a median age of diagnosis of 38 years. In Crohn’s Disease, however, there was no significant difference in median age of diagnosis which was 31 years in Hispanics and 32 years in Non-Hispanic Whites. In Hispanics 68% of UC patients were male, whereas in Non-Hispanic Whites 47% of UC patients were male which was a significant difference (P 1⁄4 0.0001) (table 1). In contrast, for CD there were no significant associations between race/ethnicity and gender (P 1⁄4 0.33) (table 2). In addition, among the UC patients, there was no significant association between race/ethnicity and disease location (P 1⁄4 0.30), or colectomy (P 1⁄4 0.17). Among the CD patients, there were no significant associations between race/ethnicity and disease location (P 1⁄4 0.52), disease behavior (P 1⁄4 0.27) or CD related surgery (P 1⁄4 0.73). CONCLUSION(S): In Hispanics, ulcerative colitis is more predominant in males and diagnosed at a younger age than in Non-Hispanic Whites. There are racial/ethnic differences in inflammatory bowel disease and further studies in minority populations are needed.