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Clinical Utility of Three-Dimensional Echocardiography for the Evaluation of Ventricular Function

The evaluation of ventricular function is a core component of 2-dimensional echocardiography (2DE). Given the known limitations of 2DE, a more accurate assessment of ventricular function has long been desired. Three-dimensional echocardiography (3DE) holds promise to fulfill this role while still maintaining the same benefits of low cost, portability, and efficiency of 2DE. Although 3DE has been investigated for over 30 years, the technology has seen little use in the modern clinical echocardiography lab. Although the benefit provided by the additional dimension of 2DE over M-Mode was immediately apparent, the clinical advantages of 3DE over 2DE have been difficult to appreciate. Several reasons for the lack of adoption include the learning curve, concerns about workflow, skepticism about clinical validity, and perceptions that the technology is too unrefined. Nonetheless, the past 2 decades have seen tremendous technical improvements in the field and a wealth of clinically applicable research. In particular, 3DE now has an established role in evaluating left ventricular systolic function. This review highlights the clinical relevancy of 3DE in evaluating ventricular function in terms of the history, relevant data, advantages, and the limitations of current generation 3DE.