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[Factors affecting intima-media thickness in carotid arteries in diabetes mellitus of the young].

The aim of the work was to measure intima-media thickness IMT), study lipid and carbohydrate metabolism and factors contributing to the development of vascular complications in type 1 and 2 diabetes mellitus (DM) of the young. It included 63 patients aged 18-40 years (40 with DM1 and 13 with DM2). Glycated hemoglobin was measured on a AzSYM immunoenzyme analyzer, lipid metabolism studied using a Cobas Integra 400 Plus analyzer, and IMT estimated based on the ultrasound technique (Volision--750 Exert with 10 MHz sensors). Patients with DM of the young showed higher IMT values than age-matched healthy subjects. IMT tended to increase after the age of 33 years and with duration of DM. DM did not cause a decrease of blood HDL levels. Smoking had negative effect on the vascular wall in DM patients.