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Clinical significance of bacteriologic screening in platelet concentrates

BACKGROUND: Despite routine bacterial screening with a bacterial culturing system (BacT/ALERT, bioMérieux) of platelet (PLT) concentrates, two cases of life‐threatening sepsis attributed to transfused PLT products contaminated with Bacillus cereus were reported to the regional hemovigilance office in the southwest region of the Netherlands. These reports necessitated a retrospective evaluation of the currently applied bacteriologic screening program.