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Inferior Vena Cava Collapsibility Index in Severe Acute Decompensated Heart Failure as Predictor of In-Hospital Mortality

Introduction: The aim of this study was to assess the relation between the diameter and collapsibility of the inferior vena cava (IVC), other markers, clinical variables and in-hospital mortality in patients hospitalized with severe acute decompensated heart failure (ADHF). Patients and Methods: An observational prospective study was conducted that included patients hospitalized with severe ADHF from April 2019 to March 2020. Inferior vena cava collapsibility index (IVCCI) was measured during the first 12 hours at admission. The endpoint was in-hospital mortality. Results: Two hundred thirty one patients hospitalized for ADHF, 28 (12.1%) of them died during hospitalization and formed non-survivors group. There were significant difference between non-survivors and survivors in case of IVVCI (21.25 ± 5.6 vs. 36.2 ± 18.3; p= 0.01 respectively). According to multivariate analysis IVCCI remained independent predictor of in-hospital mortality (p< 0.05). An IVCCI less than 23 predicted in-hospital mortality with 69% sensitivity and 75% specificity. Conclusion: In patients hospitalized with acute decompensated heart failure, a low IVCCI by 2D echocardiography at the time of admission is associated with a higher in-hospital mortality.