{'fraction_non_alphanumeric': 0.03223443223443224, 'fraction_numerical': 0.006593406593406593, 'mean_word_length': 4.485943775100401, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
A new highly selective fluorescent sensor based on a novel fluorophore for cyanide and its applications in bioimaging.

A novel highly active fluorescence chemical sensor (TBI) for CN- was synthesized based on triphenylamine-benzothiazole as a new fluorophore, which is firstly used as fluorophore for the detection of CN- . The fluorescence quantum yield of probe obviously increased used triphenylamine-benzothiazole as group. The probe possesses well selectivity towards CN- and anti-interference ability over common ions. After adding CN- , the UV-Vis spectrum of TBI changed obviously and dramatic color change from red to colorless, which can be observed clearly by naked eyes. The limit of detection for CN- was calculated to be 2.62 × 10-8 M, which well below the WHO cut-off point of 1.9 μM. The novel probe displayed fast sensing of CN- . The detection mechanism is the nucleophilic addition reaction between CN- and carbon atom -C = N- in indole salt. The π - conjugation and ICT (Intramolecular charge transfer) transition in TBI molecule are destroyed by this addition, which results in the change of fluorescence before and after the addition of CN- . Then, the mechanism was verified by theoretical calculation, 1 H NMR titration and mass spectra. In addition, the probe showed low cytotoxicity and could be used for biological imaging in HeLa cells.