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[Chaperones and their role in atherogenesis].

The combination of HSP60-specific humoral and cellular reactions is handled as the new diagnostic sign, reflecting the risk of the development of atherosclerosis, which is independent of other classic risk factors. Chaperones are identified as important pathogen-related antigens used to design vaccines against atherosclerosis. The high evolutionary homology of HSPs raises the issue on the safety of such vaccines.