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Exploring the association between lichen planopilaris, cardiovascular and metabolic disorders

Lichen planopilaris (LPP) is a rare, autoimmune form of scarring alopecia, driven primarily by a Th1 immune response similarly to lichen planus (LP) and psoriasis. Previous studies demonstrated the association between psoriasis, LP and cardiovascular disease (CVD) possibly due to increased pro-inflammatory cytokines leading to dysregulated metabolic and lipid signaling.1,2 While current reports suggest an association between LPP and other autoimmune disorders such as thyroid disease and vitiligo, the link between LPP metabolic and cardiovascular comorbidities remains largely unexplored.3,4.