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Megalencephalic leukoencephalopathy with subcortical cysts (MLC) - a case with clinical and magnetic resonance imaging (MRI) dissociation.

Received 28 August 2014; Received in final form 01 October 2014; Accepted 21 October 2014. Figure 1. (A), Axial T1-weighted image shows diffuse cerebral white-matter abnormalities with frontoparietal subcortical cysts (arrows). (B), Axial FLAIR image exhibits subcortical cysts (arrows) in the anterior temporal lobe intermingled with diffuse whitematter hyperintensity. (C) and (D), Axial T2-weighted images with diffuse white-matter abnormalities, the external and extreme capsules are involved and the posterior limb of the internal capsule shows a double-line of abnormal intensity (arrows in D). (E), Coronal T2-weighted image highlights a diffuse brain swelling with white-matter hyperintensity and persistence of the cavum septum pellucidum (arrow). (F), Sagittal T1-weighted image with fat suppression and after endovenous gadolinium contrast, note the cranio-facial disproportion without abnormal enhancement. The corpus callosum is relatively spared.