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Hidden Communication Mechanisms between Functional Regions of the Myosin Motor Domain

Figure 3. The classic model of the myosin enzyme cycle proposed by Lymn and Taylor. ATP binding to the myosin cross-bridge dissociates from the acto-myosin complex. Then in the detached state the myosin cross-bridge goes through a conformational change, of which the reversal movement after rebinding to actin causes displacement along the actin filament.