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Patient and carer views on participating in clinical trials for prodromal Alzheimer's disease and mild cognitive impairment

There is great interest in conducting clinical trials of disease‐modifying therapies in the prodromal (early, pre‐dementia), asymptomatic stages of Alzheimer's disease. Diagnostic biomarker tests offer a means of identifying prodromal patients, but it is unclear how potential participants feel about their use. Deciding whether to take part in a clinical trial is a complex process in which eligible participants must balance risks and discomforts against uncertain benefits. We sought to explore the views of potential participants through qualitative research methods.