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Churg–Strauss syndrome secondary to antileucotriene therapy in a patient not receiving oral corticosteroids

We report a case of cutaneous leucocytoclastic vasculitis temporally associated with introduction of montelukast, a leucotriene receptor antagonist (LTRA), in a patient not receiving oral corticosteroids. Anti-leucotriene agents are a relatively new asthma treatment, which target cysteinyl leucotriene receptor-1. They serve to control inflammation and bronchoconstriction, and are generally used as steroidsparing agents in patients with severe asthma. We describe a case of a 21-year-old asthmatic woman, with a background of bronchiectasis, asthma and eczema, who presented with a dramatic, rapidly progressive,