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Effect of immunoglobulin preparation on course of AIDS-related complex (ARC).

Relatively low dose treatment (150 mg/kg, once per two weeks) of a intravenous immunoglobulin (IVI) preparation has shown a beneficial effect on CD4/CD8 ratio and CD4 cell counts in two patients with AIDS-related complex (ARC). Since ARC generally progresses to AIDS with a marked reduction of CD4 cells or a marked inversion of CD4/CD8 ratio, this type of IVI treatment seems to be effective for obstructing or at least delaying the progression from ARC to AIDS.