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Embroidered biosensors on gauze for rapid electrochemical measurements

Electrochemical biosensors are useful diagnostic tools which possess the capacity for rapid detection of analytes in biofluids. Here, we report the first time embroidered electrochemical sensors on gauze for rapid measurements of wound biomarkers. Robust, flexible electrodes were successfully fabricated onto medical gauze and wound dressings via embroidery. Proof-of-concept was carried out by performing quantitative measurements of uric acid, a biomarker for wound healing, in simulated wound fluid. This gauze-based sensor exhibits excellent linearity from 0 μM to 800 μM. Additionally, we demonstrated that the gauze sensor works excellent and consistent when this is extra layer wrapping over it. Lastly, we show that this biosensor exhibits high specificity and good resilience against mechanical deformation, making it a promising platform for noninvasive wound monitoring.