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Further experience with the effect of some sugars on the growth and glycosylation of tumor line MCF-7.

The paper continues in the previous experiment indicating a possible control of glycosylation and differentiation processes in the in vitro cultured tumor cells using suitable types of saccharides in the culture medium. In this experiment the effect of lactose, L-fucose, D-glucose, and D-galactose was studied. To determine glycosylative changes the panel of six lectins with various sugar specificity was used. The obtained results indicate that a specific sugar may significantly affect not only the growth of cells but also glycosylation processes, including cell differentiation.