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HIV‐1 inhibits haematopoiesis via microRNA secreted by virus‐infected CD4+ T cells

HIV‐1‐infected patients develop haematological disorders such as cytopenias. One possible explanation is the inhibition of haematopoiesis at the level of differentiation of CD34+ haematopoietic progenitor stem cells. Based on our previous studies, we hypothesised that there may be viral encoded, or host cellular factors which participate in the process of inhibition of haematopoiesis.