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becaplermin topical

Pronunciation: be KAP ler min TOP ik al

Brand: Regranex

What is the most important information I should know about becaplermin topical?

You should not use becaplermin topical if you have cancer affecting the skin where you will apply this medicine.

Some people using becaplermin have developed cancer. However, it is not known whether this medicine actually causes cancer.

What is becaplermin topical?

Becaplermin topical (for the skin) is used to treat diabetic foot ulcers in people with normal blood flow in the legs and feet.

This medicine is not for use in treating pressure ulcers (bed sores) or ulcers caused by poor circulation.

Becaplermin topical may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using becaplermin topical?

You should not use becaplermin if you are allergic to it, or if you have cancer affecting the skin where you will apply this medicine.

Tell your doctor if you have ever had:

  • cancer; or
  • blood circulation problems in your lower legs.

Some people using becaplermin have developed cancer. However, it is not known whether becaplermin actually causes cancer. Ask your doctor about this risk.

Tell your doctor if you are pregnant or breastfeeding.

Becaplermin topical is not approved for use by anyone younger than 16 years old.

How should I use becaplermin topical?




Wash your hands before applying this medicine.

Use a cotton swab, tongue depressor, or other disposable applicator to apply becaplermin topical to your skin.

To keep the tip of the medicine tube from getting contaminated, do not allow the tip to touch any surface, including your fingers or the ulcer you are treating.

It may take several weeks before your symptoms improve. Use this medicine daily and call your doctor if your foot ulcer is not at least one-third smaller in size after 10 weeks, or if it is not completely healed after 20 weeks.

Becaplermin is only part of a complete ulcer care program that includes not putting weight on your leg and foot that is affected by an ulcer. Follow your doctor's instructions very closely.

Your doctor will need to check your foot ulcer on a regular basis.

Store the medicine in a refrigerator. Do not freeze. Keep the tube tightly capped when not in use. Do not use becaplermin topical past the expiration date.

What happens if I miss a dose?


What happens if I overdose?


What should I avoid while using becaplermin topical?

Avoid putting weight on the foot affected with a diabetic ulcer.

Avoid using other medications on the areas you treat with becaplermin unless your doctor tells you to.


What are the possible side effects of becaplermin topical?



  • an increase in the size of the ulcer, or worsening symptoms;
  • severe itching;
  • skin redness; or
  • blistering or peeling skin.

Common side effects may include:

  • red rash; or
  • burning where the medicine was applied.


What other drugs will affect becaplermin topical?


Where can I get more information?

Your pharmacist can provide more information about becaplermin topical.



Copyright 1996-2020 Cerner Multum, Inc. Version: 4.01. Revision date: 9/25/2019.

