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Effect of chloroquine on oestrus cycle and ovulation in cyclic rats

We conducted experiments to determine the effects of chloroquine (CQ) on the oestrus cycle and ovulation in 4‐day cyclic rats. There were two treatment groups. Group I animals had chloroquine phosphate (40 mg kg−1 body wt.) administered intraperitoneally (i.p.) starting from dioestrus day 1, once a day, 5 days a week for 4 weeks. Oestrus smear was monitored by daily saline vaginal lavage. Control rats received an equal volume of physiological saline. All animals were sacrificed at the end of the 4th week of treatment.