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Chewing‐Gum Preservative Induced Toxidermic Vasculitis

This paper reports the case of a young female patient who presented with a cutaneous urticarial disseminated eruption. Drug‐induced side effects were eliminated, and the only recent dietary change was the regular use of chewing‐gums containing chlorophylla (E140), menthol and BHT (butylhydroxytoluene). Immunohistological analysis of a cutaneous lesion revealed signs of vasculitis. Within 1 week after stopping chewing gum, the eruption subsided. Oral provocation tests at 4‐day intervals confirmed the responsibility of BHT by the reinduction of the cutaneous signs after a few hours.