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Production of 6-oxo-prostaglandin F1 alpha, PGF2 alpha and PGE2 by sheep uterine tissue.

Incubation in vitro of sheep uterine tissue revealed that although both caruncular and non-carunuclar endometrium can synthesize appreciabel quantities of PGF2 alpha, PGE2 and 6-oxo-PGF2 alpha, the myometrium synthesizes predominantly 6-oxo-PGF1 alpha. Non-caruncular endometrium contained more 6-oxo-PGF1 alpha than either the myometrium or the caruncles, while myometrial tissue possessed less PGF2 alpha than either caruncular or non-caruncular endometrium.