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Tetracycline-responsive Yersinia-reactive arthritis: Report of a case

Infection with Yersinia enterocolitica is an uncommon cause of arthritis in the United States. It may present either as acute septic arthritis or, more often, as sterile reactive arthritis. Antibiotic therapy has been considered to be of value only in septic arthritis. We report the first case of Yersinia-reactive arthritis to apparently respond to tetracycline therapy. A 23year-old woman developed symmetric polyarthritis 10 days after the onset of acute enteritis. She was found to have elevated titers to Yersinia enterocolitica (1:1,280) and negative synovial fluid cultures. Her arthritic pain responded poorly to high doses of aspirin and indomethacin and she ultimately required steroids and narcotic analgesics. The patient failed to respond