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[STRUCTURAL AND SPATIAL ORGANIZATION OF MICROGLIA IN THE MOLECULAR LAYER OF RABBIT CEREBELLAR CORTEX].

Using the methods of immunocytochemistry and
confocal laser microscopy, structural organization
and spatial distribution of microgliocytes in the
molecular layer of the cerebellar cortex were
studied in 5 adult male rabbits. Reaction to
microglial cell marker Iba-1 was highly specific,
while until recently their selective detection was
impossible in rabbits. In the molecular layer of the
cerebellar cortex, two patterns of microgliocyte
organization were observed. Most common were
the cells with tortuous intricately ramified
processes, the main branches of which often had
radial direction. Perivascular sparsely-branched
spindleshaped microgliocytes were also found. The
peculiarities of the structural organization of these
cells are related to the protective functions they
perform at the level of the blood-brain barrier.