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Treatment Intervention of Chronic Plantar Wart Using Gardasil 9 Vaccine - A Case Report

A case report on the regression of a hyperkeratotic chronic plantar wart, upon administration of the Gardasil 9 vaccine, is presented herein. A 42-year-old patient visited the clinic from September 2020 to May 2021, with symptoms and presentation typical of plantar wart, which contributed to severe disability while walking. The treatment prescribed was liquid nitrogen cryotherapy, curettage and topical salicylic acid. Over 7 months, the wart regressed along with severe treatment-associated inflammation, only to reappear. Gardasil 9 is administered free to secondary school children in Australia as part of the National Immunisation Program Schedule. The patient was a recent migrant and was not immunized, hence requested to be immunized. After a single dose, the patient experienced fever, shedding of wart tissue and surrounding skin. Complete healing took place within 2-3 weeks. It is thus proposed that Gardasil 9 be administered to migrants, and that it may also be considered for use as a therapeutic agent in chronic plantar warts. This may reduce the morbidity period, prevent autoinoculation, viral shedding and community spread.