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Double‐Blind Comparison of Absorbable Colloidal Bismuth Subcitrate and Nonabsorbable Bismuth Subnitrate in the Eradication of Helicobacter pylori and the Relief of Nonulcer Dyspepsia

Background. Bismuth is widely used for the eradication of H. pylori, especially in developing countries, although there are concerns over its neurotoxicity. Whether bismuth has to be absorbed in humans to act against H. pylori is not known. In this study, we compared “absorbable” (colloidal bismuth subcitrate) and “nonabsorbable” (bismuth subnitrate) bismuth as part of triple therapy in the eradication of H. pylori.