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The Role of Combined MRI & MRSI in Treating Prostate Cancer

Clinical assessment of the extent of prostate cancer (PC) is often difficult because of the relatively small size and complex anatomy of the prostate and its inaccessible location deep within the pelvis. Traditionally, the extent of PC has been evaluated by digital rectal examination (DRE) in combination with other clinical data (PSA, number of positive biopsies or core percentage positive for PC). Increased awareness of limitations of traditional methods for diagnosis and staging of PC has mobilized the development and application of new imaging modalities for its assessment. Several new non-invasive imaging techniques, such as transrectal ultrasound of the prostate (TRUSP) have been developed to aid in this evaluation. However, these diagnostic modalities still have limitations. Even when combined with other clinical tools they often cannot consistently provide all the information needed by physicians.