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Preoperative anemia in gynecologic oncology surgery: Analysis of the National Surgical Quality Improvement Program Database.

e13528 Background: Preoperative anemia has been identified as risk factor for adverse postoperative outcomes following hysterectomy for benign indications. However, studies have not yet been performed looking at the effect of preoperative anemia on women undergoing surgery for a gynecologic malignancy. Methods: We used the National Surgical Quality Improvement Program data from 2014 to 2019 to conduct a retrospective, population-based cohort study. Our exposure of interest was preoperative anemia, defined as a hemoglobin value <12 g/dL and stratified using the National Cancer Institute grading system. We preformed a logistic regression was used to calculate the adjusted odds ratio evaluate the effect of anemia on the outcomes. Results: Of the 54,569 women in the cohort, 13,232 (24.2%) had anemia. Conclusions: Preoperative anemia, at any grade, is associate with an increase in postoperative morbidity and that the effect is increased with worsening grade of anemia.[Table: see text]