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New and updated recommendations for the treatment of juvenile idiopathic arthritis associated uveitis and idiopathic chronic anterior uveitis.

OBJECTIVE
The Multinational Interdisciplinary Working Group for Uveitis in Childhood (MIWGUC) identified the need to update the current guidelines and worked to produce this document, which should serve to guide clinicians managing children with juvenile idiopathic arthritis associated uveitis (JIAU) and idiopathic chronic anterior uveitis (CAU).


METHODS
The group analysed the literature published between December 2014- June 2020 after a systematic literature review conducted by two clinicians. Paediatric rheumatologists were paired with ophthalmologists to review the eligible 37 publications. The search criteria were selected to reflect those used for the 2018 SHARE recommendations in order to provide an update, rather than a replacement for that publication. The consensus meeting was moderated by Prof Dan Furst MD, UCLA, Los Angeles, USA. The summary of the current evidence for each SHARE recommendation was presented to the expert committee. These were then discussed and revised during a video consensus meeting on the 22nd of January 2021 with 14 voting participants, using a Nominal Group Technique to reach consensus.


RESULTS
JIAU treatment was extended to include CAU. Fourteen recommendations regarding treatment of JIAU und CAU with > 80% agreement were accepted.


CONCLUSION
An update to the previous 2018 SHARE recommendations for the treatment of children with JIAU with the addition of CAU was created using an evidence-based consensus process. This guideline should help support clinicians to care for children and young people with chronic anterior uveitis.