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[Centrogenic arterial hypertension and local renal blood flow: evidence of nervous regulation of medullary circulation].

Blood flow through the cortex and medulla of the rat and rabbit kidney was measured with the hydrogen wash-out technique. Stimulation of the midbrain RF caused vasoconstriction both in cortex and medulla. This constriction was abolished by kidney denervation and became stronger under conditions of stabilized arterial blood pressure. The data obtained suggest that both the cortical blood flow and the medullary one are continuously controlled by extrarenal neural influences. These influences are reduced when renal perfusion pressure rises and are modulated by the intrarenal autoregulator mechanisms.