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Epper Syndrome: An Additional Case

Letters to Dermatology This study, despite the small number of patients treated, shows that local side effects induced by SCT with tazarotene are less frequent and severe in comparison with the traditional treatment with the same drug. Furthermore, the short duration of the application of tazarotene, followed by washing, greatly improves patient compliance. Clinical improvement was observed in 12/16 patients (= 75%). As far as the effectiveness of SCT is concerned, this regimen seems to be as active as the traditional treatment with tazarotene. However, improvement induced by SCT is slower. Duration of application seems to be related to the appearance of improvement, e.g. short application → slower appearance of improvement. Following a very short contact (e.g. 5 min), first signs of improvement are seen about 3 weeks later; following a 20-min application, improvement is seen 7–10 days later. A controlled clinical study based on a larger number of patients is necessary in order to confirm these results.