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Designing a novel antacid for sensitive populations

journals.sagepub.com/home/taw 257 Heartburn is one of the most common medical complaints that can affect every age group of patients all over the world. It is characterized by some kind of pain sensation from around the sternal manubrium to the neck base.1 As a symptom of esophageal irritation or injury, heartburn is a strong indicator of gastroesophageal reflux disease (GERD). Prevalence of these debilitating symptoms is up to 20% in western populations with at least weekly frequency.2 Rate of occasional incidents has been reported even higher, up to 60%.3