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Correlation of SNPs in exon 1 of loxl‐1 gene with pseudoexfoliation syndrome in patiens from Western Greece

Purpose Pseudoexfoliation (PEX) syndrome is a clinically important systemic disorder of the extracellular matrix characterized by pathologic accumulation of an abnormal fibrillar material in various ocular tissues. LOXL1 is a cross‐linking enzyme in extracellular matrix metabolism and is required for elastic fiber formation. Single nucleotide polymorphisms (SNPs) in exon 1 of the lysyl oxidaselike 1 (LOXL1) gene have been recently identified as strong genetic risk factors for PEX syndrome. The purpose of this project is to correlate certain Single Nucleotide Polymorphisms (SNPs) in exon 1 of the gene loxl‐1 with patients from the area of Western Greece who present PEX syndrome