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Evaluation of Digitalis Toxicity By Salivary Electrolytes

From the Department of Medicine, Misericordia-Fordham Hospitals, Bronx, New York and New York Medical College. Digitalis is one of the most widely used drugs and digitalis intoxication is still a very common problem.’ A simple test to establish the presence or absence of digitalis toxicity would indeed be beneficial. Recently, Wotman and his associates2 described such a simple assay. By measuring the salivary calcium and potassium and calculating its product, these workers found that one could easily identify patients with digitalis toxicity. Unfortunately digoxin serum levels were obtained in only 5 of the 18 patients considered to have digitalis toxicity, and in only two of them was the serum level of digoxin definitely excessive.