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Fever: a return to basics!

Fever is a physiological response to infection which seems to have evolved and been preserved in humans over eons of time. It is a protective mechanism and, except for the rare circumstance of a central nervous system condition such as hypothalamic disease, the body will not allow lethal hyperpyrexia so long as (a) hydration remains adequate and (b) the body is provided an environment which allows for heat loss(1). As such, the primary question should actually be not how to best treat fever but whether to treat it at all!