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DERMATOPHYTE SOLE CARRIERS. A PRELIMINARY STUDY IN PATIENTS WITH CLINICAL EVIDENCE OF DERMATOPHYTOSIS

Keratinophilic fungi have an enormous environmental value due to its role in degradation of keratinized materials that exist in nature. During clinic routine, however, it has been observed that 50% of total filamentous fungi causing lesions in keratinized tissues are not dermatophytes but airborne fungi. Considering beaches as a very used place where people are more susceptible to acquire infections, a study was proceeded over this issue. It reports to keratinophilic activity in a great variety of fungal species. They were isolated, most of them, from this environment. Using methods like hair perforation in vitro and having recourse to optic, fluorescence and scanning electron microscopy it was observed that some fungi, thought as without keratinophilic activity, have a relevant intensity of keratinolytic activity (IKA). For some filamentous fungi studied tests were made to check their susceptibility to different antifungal substances, in order to determine which of them are more effective in combat against infections. Tioconazole seems to be most effective against keratin degradation.