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Penile erection induced in vivo by a purified toxin from the Brazilian spider Phoneutria nigriventer

To verify the effect on erectile tissue of mice of two neuropeptides extracted from the poison of a spider, Phoneutria nigriventer, (Tx2‐5 and ‐6, termed ‘eretina’) after direct injection into the corpus cavernosum, to assess the minimum dosage necessary for effect, the time for initiation of action, the local duration of the erection, histological effects and the presence of local and systemic side‐effects.