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Protective role of steroids on mouse primary RPE cells under hypoxic stress

Purpose Angiogenesis is a clinically critical aspect of the pathogenesis of many retinal neovascular diseases. Triamcinolone acetonide (TA) is an important anti‐angiogenic and anti‐inflammatory agent. This study has evaluated the effect of TA on the expression of pigment epithelium derived factor (PEDF), thrombospondin‐1 (TSP‐1) and vascular endothelial growth factor A (VEGF‐A) in cultured mouse RPE cells under hypoxic stress.