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Atypical takotsubo cardiomyopathy with left ventricular apical wall sparing: A case report and literature review.

BACKGROUND
Takotsubo cardiomyopathy (TTC) is an uncommon cause of acute reversible ventricular systolic dysfunction in the absence of culprit obstructive coronary artery disease (CAD). Typically manifesting as apical wall ballooning, TTC can rarely present atypically with apical wall sparing.


CASE REPORT
A 62-year-old female presented with complaints of chest pain and features mimicking acute coronary syndrome. Coronary angiogram revealed no obstructive CAD and left ventriculogram showed reduced ejection fraction, normal left ventricular apex and hypokinetic mid-ventricles consistent with atypical TTC. The patient was discharged home on heart failure medications and a follow-up transthoracic echocardiogram demonstrated improved left ventricular function with no wall motion abnormality.


CONCLUSION
This case report provides an insight into the diagnosis and management of TTC in the absence of pathognomic features.