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Ampicillin compared with penicillin and chloramphenicol combined in the treatment of bacterial meningitis.

Abstract : The report is a prospective treatment study of 187 patients with purulent meningitis admitted to the Abbassia Fever Hospital, Cairo, U.A.R. The causative organism was grown from the spinal fluid in 66% of the cases. Of the culture positive cases, 49% were due to Neisseria meningitidis, 29% to Diplococcus pneumoniae, 12% to Haemophilus influenzae and 10% to miscellaneous organisms. The data indicate that these are the predominant organisms causing meningitis in the U.A.R. and that ampicillin is an effective single drug in the treatment of bacterial meningitis.