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Guidelines for Substance Abuse Research Involving Children and Adolescents

The National Advisory Council on Drug Abuse (NACDA) recognizes that substance abuse research involving children and adolescents is vital to understanding factors contributing to the initiation, maintenance and cessation of substance use and abuse among this population. This period of life is characterized by growth and maturation of brain and body, which potentially affects responses to drugs and treatment. Moreover, the great majority of people who develop substance use disorders (SUDs) or addiction begin to use drugs when they are young. Therefore, study of this population is crucial in order to develop effective prevention and treatment interventions, both behavioral and pharmacological, for youth.