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Issues in Renal Transplantation of Patients With Donor‐Specific Antibodies and Negative Flow Cytometry Crossmatches

We thank Dr. Kamoun and Ms. Kearns for their interest in our study of kidney transplant recipients with pretransplant donor-specific antibodies (DSA) despite negative flow cytometry crossmatches (FCXMs) (1). We agree with many of their points. We concur that our study evaluated a relatively small number of DSA-positive patients (20); we had acknowledged this limitation in our discussion. Prior reports of patients with pretransplant DSA and negative FCXMs, however, have included even fewer patients (2), or only followed them during the first few posttransplant weeks (3).