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Development and evaluation of a pulsed nebulizer with predictable dosing characteristics.

A metered dose nebulizer assembly with the capability for repeatable doses is described, comprising a commercial disposable nebulizer and a timing circuit to control the duration of air supply. Data on performance of the nebulizer apparatus under typical operating conditions are presented, using cromolyn sodium as a model compound. Repeat doses from the apparatus typically show less than 10% relative standard deviation.