{'fraction_non_alphanumeric': 0.022702702702702703, 'fraction_numerical': 0.003243243243243243, 'mean_word_length': 5.299319727891157, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
[Analysis of the biocompatibility of a new PLGA/fish skin collagen conjugated electrostatic spinning film].

PURPOSE
To study the biocompatibility of a new polylactic acid-glycolic acid(PLGA)/fish skin collagen conjugated electrostatic spinning film.


METHODS
PLGA and medical-grade fish skin-I collagen were used as raw materials to prepare nanometer fiber films by conjugated electrostatic spinning technique. Mouse fibroblast L929 was used as a model to evaluate its cell and histocompatibility, which provided experimental basis for application in guided bone regeneration (GBR).


RESULTS
Fibroblasts showed good adhesion and growth on the surface of fiber membrane; there were a large number of deep pseudopodias, which were arranged along the orientation of fibers.


CONCLUSIONS
PLGA/fish skin collagen conjugated electrostatic spinning membrane is beneficial to fibroblast growth and is expected to be used for GBR.