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Mosquitocidal activity of Ophiocoma scolopendrina extracts against Culex pipiens and their antimicrobial potential

The current study aimed to study the potential mosquitocidal activities of the crude extract of the brittle star, Ophiocoma scolopendrina against the mosquito vector, Culex pipiens. Regarding the antimicrobial potential of O. scolopendrina , dichloromethane exhibited higher activity than the other solvents; whereas, it could inhibit a wide range of the tested strains with a moderate potential when compared to the positive controls. Larval mortalities of the current study revealed promising insecticidal and antimicrobial activities of the brittle star, Ophiocoma scolopendrina crude extract against the mosquito vector, Culex pipiens. Larval mortalities were increased in a concentration-dependent pattern. Ethyl acetate, dichloromethane and ethanol extracts recorded the highest larval mortalities. Tested extracts played a major role in disrupting the emergence of adults with slight to moderate effects on the sex ratios of emerged adults. Additionally, tested extracts exhibited severe repelling activity for LC 50 treatments and this effect was much more pronounced in the LC 95 treatments which give an indication for these natural-origin extracts repellent properties. Overall, based on obtained results and besides therapeutic properties, tested extracts and its active constituents can be exploited in integrated pest management programs.