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Discrepancy in Fluorescein Angiography and Optical Coherence Tomography Findings of Macular Edema in Intermediate Uveitis

ABSTRACT Purpose: To assess discrepancies between fluorescein angiography (FA) and optical coherence tomography (OCT) findings for macular edema (ME) in intermediate uveitis, and investigate treatment response differences corresponding to the discrepant patterns. Methods: Discrepant results for ME detection between FA and OCT were evaluated. After 6 months, differences in treatment responses were analyzed. Results: Discrepant findings for ME were found in 21 (44%) of 48 eyes. The best-corrected visual acuity significantly improved after treatment in the concordant group but not in the discrepant groups. Central retinal thickness significantly decreased after treatment in the FA+/OCT+ and FA−/OCT+ groups but not in the FA+/OCT− group. Disease duration was significantly longer in the FA+/OCT− group than in the other groups. Conclusions: Discrepancies in FA and OCT findings for ME were common in patients with intermediate uveitis. Our results suggest that treatment outcomes may differ according to the discrepant patterns.