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The relation between body mass index and plasma total cholesterol in a multiracial sample of US schoolchildren.

The relation between body mass index expressed as weight in kilograms divided by height in meters cubed (weight (kg)/height (m3)) and plasma total cholesterol was assessed in a sample of 11,389 US schoolchildren, aged 5-18 years, between 1984 and 1989. Among whites and Hispanics, a statistically significant nonlinear relation was found between weight (kg)/height (m3) and plasma total cholesterol. Mean cholesterol values increased exponentially above the 50th percentile of body mass index. Additionally, mean cholesterol levels as well as the odds of hypercholesterolemia (total cholesterol value greater than 180 mg/dl) were highest among children with weight (kg)/height (m3) values above the 95th percentile. Among black children, weight (kg)/height (m3) did not appear to be related to plasma total cholesterol. Possible explanations as well as public health implications of these findings are discussed.