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Electrospun Poly(L-lacticacid)/Nano-Hydroxyapatite Hybrid Nanofibers and Their Potential in Dental Tissue Engineering

Efficacy of poly(L-lactic acid) (PLLA)/nano-hydroxyapatite(HA) hybrid nanofibrous scaffolds for dental tissue engineering is described and their performance on normal cells with MG-63 is compared as well in this study. Perfectly PLLA/HA fibrous scaffolds were fabricated by an electrospinning process under optimal condition. Cell culcure and adenovirus encoding green fluorenscent protein technique were used to study the morphology of cells grown on the scaffolds. The results show that the growth of DPSCs and PCs is well observed attached to the PLLA/HA fibers, as well as MG-63, which indicate that the nanofibrous PLLA/HA scaffold could be used as a potential cell carrier in dental tissue engineering.