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[Clinical evaluation of cellular pathophysiology in cardiovascular diseases with radionuclide biochemical imaging].

Myocardial imaging with radionuclide biochemical tracers has provided advanced diagnostic approaches for patients with coronary artery disease and heart failure. Since the biochemical information includes cellular events such as metabolism, inflammation, and sympathetic drive, it can be regarded as one of 'Molecular Imaging'. In this chapter, I introduce topics on clinical evaluation of cellular pathophysiology in cardiovascular diseases with radionuclide biochemical imaging: detection of coronary vulnerable plaque to predict the occurrence of acute coronary syndrome and estimation of altered myocardial metabolism and sympathetic drive to estimate the severity of myocardial failure.