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The value of cervical punch biopsy in the assessment of histopathological prognostic factors in carcinoma of the cervix.

From 1976 to 1980, 88 patients with stage Ib and early stage II squamous cell carcinoma of the cervix had the histological slides of their pretreatment cervical biopsies reviewed. Histological features of the biopsied tissue like cell type, cell differentiation, lymphatic or vascular permeation and stromal inflammatory cell reactions were assessed. In contrary to previous studies, the present study failed to show any significant correlations between these various histological features and the survival rate except in patients with moderate to severe plasma cell infiltration who had a better survival rate than those with absent to minimal plasma cell infiltration. Cervical punch biospy is of no value in the prediction of the prognosis of patients with squamous cell carcinoma of the cervix.