{'fraction_non_alphanumeric': 0.023391812865497075, 'fraction_numerical': 0.005847953216374269, 'mean_word_length': 5.119047619047619, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Research Progress of APP/PS1 Mice on Neuronal Apoptosis

Neuronal loss, mainly caused by neuronal apoptosis, is an important pathological feature of Alzheimer’s Disease (AD). APP/PS1 double transgenic mouse can primely simulate the pathologic changes of AD, which makes this kind of mouse an internationally recognized transgenic AD animal model and be widely used in the relevant research of AD. This review provides a brief summary of the application situation of APP/PS1 mice to AD neuronal apoptosis research.