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Tamoxifen and endometriosis. Case report

A 44-year-old woman had received 20 mg of tamoxifen daily for three years, for the treatment of breast carcinoma. She attended the gynaecological clinic because she had had intermenstrual and postcoital bleeding for six months and amenorrhoea for four months. She had a hysterectomy and bilateral salpingo-oophorectomy for the relief of her symptoms. Examination of the operation specimen showed severe simple endometrial hyperplasia and simple hyperplasia was also present in the endometriotic foci in the ovary