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Chronic Eosinophilic Gastroenteritis in the Horse

Four cases of chronic eosinophilic gastroenteritis in horses are described. The disease was manifested clinically by weight loss, malabsorption and diarrhea or soft, formless feces. A chronic inflammatory reaction, with diffuse and focal eosinophilic infiltrates, was present in the esophagus, stomach, small and large intestine, and mesenteric lymph nodes. The cause of the lesion was not determined but was thought to be due to an ingested allergen, as the lesion is indicative of an on-going, immediate hypersensitivity reaction. One horse had generalized acanthosis, hyperkeratosis, and ulcerative coronitis.