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The Normal Child. Some Problems of the Early Years and their Treatment

to general atheroma and cardiovascular disease. Although the treatment is kept relatively elementary, the work is of high fundamental scientific merit. The very rapidly expanding field of lipids and lipoproteins has been compressed within 5 brief chapters and this has been achieved by selecting essential information and omitting details which are available in larger reference works. The nomenclature, chemical composition and classification of lipoproteins are described. The tissues in which the lipoproteins are synthesized, metabolized and catabolized are discussed. The clinical implication of hypercholesterolaemia and hypertriglyceridaemia and the major risk factors which are important in the aetiology of atherosclerosis are well presented. A small chapter is devoted to the benefits of risk factor intervention. Since it is well recognized that the chances of atherosclerosis are meagre, early intervention by dietary management and avoidance of cigarette smoking has been suggested. The measurement of lipids and lipoproteins and the interpretation of the results are briefly documented. The authors suggest that the merits of intervention may be debatable in survivors of a myocardial infarct but any of their relatives with significant hyperlipidaemia who are still free of cardiovascular disease may be important subjects to benefit by such intervention. The final chapter gives a practical guidance to the management of hyperlipidaemia by dietary management and by drug therapy.