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Confirmation of the association of the R620W polymorphism in the protein tyrosine phosphatase PTPN22 with type 1 diabetes in a family based study

In a hand-off method in a CDMA cellular system, whether a frequency in use is a frequency layer boundary is determined in response to a notification indicating a deterioration in the frequency in use from a mobile unit. A frequency prepared in both a communication cell and an adjacent cell is selected when the frequency in use is the frequency layer boundary. Inter-frequency hand-off is executed in the communication cell by using the selected frequency. Inter-cell hand-off is executed in response to a notification indicating a destination cell from the mobile unit, which is based on a pilot signal strength measurement result from the adjacent cell.