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Prediction of radiosensitivity of individual mice by multidimensional analysis.

Ten physiological indices on each mouse were measured before an exposure to ionizing radiation. The exposure of mice to 700R of X-rays induced 45% mortality within 30 days. A prediction of death or life of each mouse was done by a multidimensional quantification. The highest success rate of prediction was obtained by using all ten indices and it resulted in 74.1%. Accordingly, it was possible to predict death of individual mice exposed to a dose around LD50 (30) with a high rate of success. When one selected five indices out of the ten indices by some criterion, the success rate of prediction decreased to 67.1%.