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Conjunctival squamous cell carcinoma as a second primary malignancy in a patient with colon adenocarcinoma

Second primary malignancies (SPM) are observed in up to 8.1% of cancer patients and are often overlooked. We present the case of a 58-year-old male with ongoing treatment for colon adenocarcinoma who was discovered to have a mass in the conjunctiva in his right eye. Other than his oncologic diagnosis, he had no other risk factors, such as a history of smoking, unusual exposure to ultraviolet radiation, fair skin, or other conditions, that could explain the lesion.