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Enhancement of the 7α-Dehydroxylase Activity of a Gram-Positive Intestinal Anaerobe by Flavins

The addition of flavins to the growth medium specifically enhanced the 7α-dehydroxylation of bile acids by anaerobically growing cultures of a Eubacterium lentum-like intestinal anaerobe, strain c-25, without an increase in cell growth. The order of the enhancement of the reaction was flavin adenine dinucleotide > flavin mononucleotide ≫ riboflavin.