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Correlations between unsatisfactory colposcopy, cytology, and biopsy in patients with cervical abnormalities

Background. The main purpose of this study is to review the clinical features of negative loop electrosurgical procedure (LEEP)‐cones, in order to lower their rate. Methods. Some 162 patients with LEEP‐cones were reviewed. Control cytology, satisfactory‐unsatisfactory colposcopy, biopsies and endocervical curettage (ECC) were compared to the presence or absence of cone pathology. Statistical analysis, t‐tests and Pearson χ2 tests were performed, with a significance level of p<0.05. Results. Negative cones are associated with unsatisfactory colposcopy in 47/60 cases (78.3%) compared to 13/60 (21.8%) for satisfactory colposcopy (p = 0.011). Unsatisfactory colposcopy is associated with a negative ECC in 53/74 (71.6%) cases, compared to 21/74 (28.4%) for satisfactory colposcopy (p = 0.024). Finally, negative ECC are associated with negative cones in 32/41 (78%) compared to 9/41 (22%) for positive ECC (p = 0.002). Conclusions. Low grade cytology, CIN1 biopsies and ECC should be followed for at least 1 year. This results in a lowering of cone negativity from 60/162 (37%) to 32/162 (19.8%).