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Molecular Analysis of Staphylococcus aureus Blood Isolates Shows Lack of Polyclonal Bacteremia

ABSTRACT Molecular analysis of the first blood culture from 41 patients with Staphylococcus aureus bacteremia and 20 bacteremia-associated catheter tip isolates revealed indistinguishable blood colonies in 39 patients (95.1%) and two related variants in two patients (4.9%). Polyclonal bacteremia was not observed in any patient, including four with genetic diversity in the catheter tip isolate.