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Antitetanus immunity in newborn findings in a sample of population in the Siena area (Italy).

Immunity against tetanus in newborn and in mother-newborn couples was studied in a sample of population from the Siena area, Italy. Mother-newborn antitetanus antibody transfer and the decrease of passively acquired antitoxin, in newborn after birth, were evaluated too. Antitetanus immunity was detected by a passive haemagglutination assay. A high rate of immunologically unprotected newborns was found owing to the low immunisation rate in mothers. The important role played by general prophylactic measures in neonatal tetanus prevention is remarked and a systematic antitetanus immunity screening, during pregnancy, is suggested in order to enhance antitetanus protection in newborns and mothers by immunisation practices.