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Blood Disappearance Rates of Certain Hormones and Enzymes Advocated as Fetoplacental Function Tests

The puerperal blood disappearance rates of three hormones (unconjugated 17β estradiol, total estriol, and human chorionic somatomammotropin) and three enzymes (heat stable alkaline phosphatase, cystine aminopeptidase, and diamine oxidase) purported to be useful as indices of fetoplacental status have been simultaneously determined in 7 subjects. Disappearance rates of the hormones were faster (minutes) than the enzymes (days) providing a theoretic lime advantage of the former in minimizing time lost between fetoplacental compromise and its earliest possible detection.