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New Method for the Incorporation of Soluble Bioactive Glasses to Reinforce Porous HA Structures

The most widely used calcium-phosphate ceramic in clinical applications is hydroxyapatite, Ca10(PO4)6(OH)2, however its dissolution rate in the human body after implantation is too low to achieve good results and it has poor mechanical properties. Recently, glass reinforced hydroxyapatite composites (GR-HA) have been developed, in order to improve the mechanical properties and to increase the similarity between implants and bone. The addition of a P2O5 based glass to a hydroxyapatite matrix, promotes the liquid phase sintering, improving the mechanical properties of the final bodies, and enabling the formation of two other calcium-phosphate phases, which have a higher dissolution rate, more compatible with bone regeneration. However, some of these glass compositions are soluble in water, making their incorporation in aqueous slurry impossible. Therefore, the aim of the present work is to study a new alternative method for the incorporation of soluble P2O5 based glass into macroporous structures obtained by different methods.