{'fraction_non_alphanumeric': 0.02845927379784102, 'fraction_numerical': 0.022571148184494603, 'mean_word_length': 5.181818181818182, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Evaluation of proficiency survey results for serum immunoglobulins following the introduction of a new international reference material for human serum proteins.

A new international reference material for 14 human serum proteins was certified by the Bureau Communitaire de Reference, Brussels, Belgium, in 1992 and released as CRM 470 (1). The same material was released in the United States by the College of American Pathologists (CAP) in 1993 as the Reference Preparation for Proteins in Human Serum, or RPPHS (2)(3). The large interlaboratory variance of values obtained on national quality control samples before 1990 was one of the major reasons for the preparation and introduction of this new material (3)(4)(5).

We undertook the present study to determine what effect, if any, the introduction of RPPHS has had on results of the CAP surveys for the major immunoglobulins IgG, IgA, and IgM. The overwhelming majority of clinical assays in the US are performed by immunonephelometry, utilizing the Beckman or …