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Keratoacanthoma-type squamous cell carcinoma developing in a skin graft donor site after tumor extirpation at a distant site.

The development of squamous cell carcinoma in split-thickness skin graft donor sites is rare in the reported literature. We report a case of keratoacanthoma-type squamous cell carcinoma developing in a split-thickness skin graft donor site 6 weeks after orbital exenteration for squamous cell carcinoma. We review the literature and discuss possible causes.