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A highly sensitive immunoassay for interleukin‐6 in dried blood spots

Interleukin‐6 (IL‐6) is a pro‐inflammatory cytokine that is associated with the production of C‐reactive protein, the acute phase response, and chronic low‐grade inflammation. In this report, we describe and validate a highly sensitive enzyme‐linked immunosorbent assay (ELISA) for quantifying IL‐6 at low concentrations in samples of capillary whole blood collected from a simple finger stick and dried on filter paper (dried blood spots, DBS).