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Quality of life assessment in schizophrenia: Applicability of the Lehman Quality of Life Questionnaire (TL-30)

The aim of the present study was to investigate the applicability of a quality of life self-rating scale—the Lehman Quality of Life Questionnaire TL-30—to evaluate the test–retest reliability of the TL-30 and finally to test the quality of life in schizophrenic patients compared with a general population. Patients with ICD-10 F20 schizophrenia were included. An interviewer-administrated quality of life instrument, the Lehman's QoLI interview guide, and two questionnaires, the Lehman TL-30 and the Medical Outcome Study (SF-36) were used at baseline. Hereafter the two questionnaires were completed again 2 weeks after discharge from hospital for the evaluation of test–retest reliability. A total of 56 patients were interviewed and 40 patients (or 71%) completed the questionnaires. Statistically significant correlation was found between the interview form and the questionnaire version. The test–retest coefficients were at the same level (approximate 0.70 for most Lehman subscales) as found for the SF-36 subscales. Compared with the general population, lower health-related quality of life (SF-36) was found in schizophrenia (P<0.01). The results of the present study confirm that the Lehman Quality of Life questionnaire can be validly used in stable schizophrenics.