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Haemorrhagic bullae induced by oral anticoagulants

Abstract. A 77‐year‐old patient developed haemorrhagic bullae on her fingers 30 months after initiation of anticoagulation treatment with warfarin sodium for chronic atrial fibrillation and mitral insufficiency. The bullae resolved 10 days after discontinuation of the medication. Two weeks after initiation of sintrom, (3‐α‐(4‐nitrophenyl)‐β‐acetylethyl‐4‐hydroxy coumarin), the lesions recurred and resolved again upon cessation of the drug. This adverse skin reaction has not been hitherto reported.