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Editorial review: engineering modelling and intelligent computing are synergistic in translational medicine research

The field of engineering modelling and intelligent computing research has developed a large and substantial body of knowledge, based mostly in medical, healthcare, science and engineering programs. The basic paradigm has been the use of engineering and computational techniques, with the randomised clinical trial forming the main basis for progress. Quantitative models to analyse questions related to healthcare and personalised medicine have been used to design, validate and support the effective clinical applications. The use of advanced engineering and computational models to solve biomedical and healthcare problems for optimal design or resource allocations are key components of personalised medicine for decades. The development, implementation and transfer into clinical practice of data-driven models to support biological and medical research is an important research area in related fields. This special issue contains several ongoing research projects aimed at developing current signal and imaging and functional informatics techniques focusing on modern engineering modelling and computational medicine. Those papers represent important original scientific contributions to the modern biomedical and healthcare fields.