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Hypersensitivity to local anaesthetics

turned positive after the challenge test. It could be because of, as it has been reported with other drugs, the loss of immunologic memory, because it had occurred 1 year earlier. Thus, although skin test is useful in the diagnosis, a negative result should be cautiously interpreted when the reaction had not occurred recently. We encourage the study and reporting of IgE-mediated reactions to LAAG for a better knowledge of cross-reactivity among these drugs (6).