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Arginine vasopressin release following surgical operations

A study of plasma arginine vasopressin (AVP) concentrations in 16 patients undergoing uncomplicated cholecystectomy was carried out to determine the relative importance of the various stimuli to AVP secretion during and after an operation. Eight of the 16 patients were given a high epidural blockade from T4 to T12 and blood samples were taken before, at frequent intervals during and for two days after operation for determination of plasma AVP and osmolality; systolic blood pressure was measured each time a blood sample was taken.