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Translational research and neurological rehabilitation: a new direction is needed.

Basic science medical research is only valuable when it translates into medical treatments or disease prevention strategies that ultimately bring benefits to patients even when cure is not possible and disease progression is inevitable. Although the main research priorities in rehabilitation medicine, that is, building research capacity and defining the research agenda, have been clearly stated (Frontera, 2009), to date basic biomedical science research in chronic neurological disease has taken different directions without a coherent theoretical framework that addresses issues beyond the disease pathology and the impairments that result from it. Thus, it has failed to address the total impact of disease on the individual, their carers, and society.