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Recurrent Graves disease spanning 24 years.

THE THERAPY of the diffuse toxic goiter of Graves disease is directed at the thyroid gland, the effector of the disease, rather than the underlying stimulus to its overactivity. Thyroidectomy and radioactive iodine are employed in an attempt to eliminate enough tissue to render the patient euthyroid. Once the euthyroid state is achieved, permanent control of the disease occurs in 92 percent to 98 percent of the patients treated by thyroidectomy' and in greater than 99 percent treated with radioactive iodine.2 The purpose of this communication is to report the unusual recurrence of Graves disease 17 years following attainment of euthyroidism.