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Congenital anemias in Macau.

The implementation of a Primary Health Care system in Macau has created the need to study the prevalence of Congenital Anemias in the population to facilitate the planning of measures needed for their control. Blood samples from 3815 women attending the antenatal clinics were screened for beta-thalassemia using MCH values as the preliminary test, followed by quantitation of Hb A2 and Hb F. Isoelectric-focusing was used to screen 1091 cord blood samples for the presence of Hb Bart's. The prevalence of alpha- and beta-thalassemia carriers was found to be 6.2% and 3.6%, respectively.