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Pyrido-1,2-thiazines and their in vitro antibacterial evaluation.

A series of known and newly synthesized pyrido-1,2-thiazine derivatives of type 3-6 were evaluated against strains of Mycobacterium fortuitum (PCM 672) and Staphylococcus aureus (PCM 2602) The pilot experiments showed that most of the compounds in initial in vitro microbiological evaluation were not efficient antibacterial agents, but unexpectedly promoted replication of the microorganisms in the range of 10-50%.