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Selecting protein fuzzy contact maps through information and structure measures

Protein contact maps are representations of the proteins three dimensional folding topology. A fuzzy generalization of contact maps (FGCM) provides to the researcher flexibility not present in standard (i.e. crisp) contact maps but it also changes the information content of the data. To aid in the rationale –rather than ad-hoc- selection of generalized contact maps parameters we introduce some universal measures of information. We discuss this in the paper and show its impact on FGCM.