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Ekbom’s Delusional Parasitosis: A Systematic Review

Objective To collect evidence-based and detailed up-to-date knowledge, using a detailed systematic review of the literature, that is specific to the condition of Ekbom syndrome, also known as delusional parasitosis (DP). This article reviews historical facts, epidemiology, pathogenesis, clinical features, subtypes and related conditions, associated diseases, psychosocial impact, economic considerations and management. Background DP is a psychiatric condition and can be the earliest sign of a major psychotic illness. The condition was first described in the late 17th century in France. The etiology is neurochemical. The classic ‘matchbox’ and ‘specimen’ signs are characteristic. Treatment is via a multidisciplinary approach. Methods A detailed search strategy was utilized across six databases led by prespecified keywords (62 in total), followed by the application of database-specific filters to scrutinize the hierarchy of literature for guidelines, systematic reviews, and randomized controlled trials in addition to medical papers with weak evidence. Results A total of 38 references were used to extract the most relevant data. This article is divided into sections of topics, starting from a methodology to a conclusion. Conclusion This review article will enable the medical researcher to obtain a detailed perspective of the condition of DP. Thus, a researcher can seek the highest evidence to initiate his original research.