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Failure to confirm increased longevity in Drosophila melanogaster submitted to a food restriction procedure.

Several studies have shown that, contrary to what occurs in rodents and in some invertebrate species, food restriction has no positive effect on longevity in Drosophila melanogaster. However, Chippindale et al. (1993) reported that flies subjected to food restriction, by modulating the yeast level, could live longer. In the present study we used the same yeast levels as Chippindale et al. in an attempt to confirm these results. No positive effect of food restriction on longevity could be observed in either sex in mated and virgin flies.