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Extent of coronary atherosclerosis in diabetic and nondiabetic patients by multislice CT calcium scoring

Objectives: The purpose of this study was to evaluate the differences in the extent of coronary atherosclerosis in patients with (type I and type II) diabetes as compared with patients without diabetes by multislice computed tomography calcium scoring and its effect on the patency of coronary arteries in patients referred for multislice computed tomography. Background: The calcium score is an important method for the assessment of coronary atherosclerosis. Participants and methods: This study was conducted on 90 patients: 30 of them with known type I diabetes mellitus (DM) (on insulin), 30 patients with type II DM (on oral treatment) and the other 30 participants without DM. Results: Results of the current study showed that the calcium score was significantly higher among patients with DM than among controls (P < 0.005). Results also showed that the mean number of affected vessels was significantly higher among the studied patients than among the controls (P < 0.001).The percentage of obstructive lesions was significantly higher among the studied patients than among controls (P < 0.026). The calcium score was significantly higher among diabetic patients with obstructive lesions in comparison with diabetic patients with nonobstructive lesions (P < 0.001). Conclusion: The calcium score is an accurate method for determining the presence and the extent of coronary atherosclerosis, especially in patients with DM. The calcium score was significantly higher among patients with DM than among controls. The mean number of affected vessels and the percentage of obstructive lesions was significantly higher among the studied patients than among controls. The calcium score was significantly higher among diabetic patients with obstructive lesions in comparison with diabetic patients with nonobstructive lesions.