{'fraction_non_alphanumeric': 0.029143897996357013, 'fraction_numerical': 0.024286581663630843, 'mean_word_length': 5.412451361867705, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Interim Assessment of Vitamin D Sufficiency in a Prospective Cohort of Late Postmenopausal Women

Objective: to assess vitamin D repletion in prospective cohort of late postmenopausal women and to establish the contribution of vitamin D deficiency and measures for its prevention to physical functioning of women. Material and methods. 107 postmenopausal Middle Urals region residents were recruited to a prospective cohort nested cross-sectional study. The data were obtained from 2016 to 2019. Results. According to the concentration level of 25(OH)D, an adequate level was detected in 24 patients (22.4%), insufficiency in 35 (32.7%), deficiency in 48 cases (44.8%). No significant seasonal differences in vitamin D levels were found. Patients significantly differed in age, according to the wrist dynamometry of dominant hand and according to results of tandem test. By the inclusion visit, 89 patients (83.1%) were not receiving vitamin D supplementation, 18 persons (16.8%) were compliant to cholecalciferol prophylactic doses consumption, had significantly higher values of 25(OH)D in the blood. Vitamin D deficiency and insufficiency in the group not receiving cholecalciferol were significantly more common than in the group who followed the recommendations. Conclusion. Deficiency and insufficiency of vitamin D are detected with high frequency in the residents of the Middle Urals in late postmenopause. Prophylactic administration of cholecalciferol did not achieve optimal concentration of vitamin D, but contributed to its higher values. Women who were optimally provided with vitamin D had significantly better physical functioning.