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Effects of weightlessness on astronauts--a summary.

This paper reviews the adaptive changes observed in the United States astronauts during flight programs to this date. A series of postulates are offered as to what is happening in these adaptive events. A hypothesis is proposed as to the interrelationship of events observed in the body systems and functions involved. The importance of undertaking an extensive life sciences program. including an on-orbit phase of study as well as pre- and post-flight studies is discussed. Finally, the role the Skylab flight plays in the United States Space Program in achieving the future requirements for more extensive life sciences data is summarized.