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Dietary supplementation of Walnuts could reduce MPP+ induced neurotoxicity in human neuroblastoma SH‐SY 5Y cells

Oxidative stress and mitochondrial dysfunction mediated neuronal apoptosis is reported to play a major role in the pathology of Parkinson's disease. Walnuts are able to offer protection to neurodegenerative disease models and rich in natural antioxidants. In the present study, we investigated the protective effects of walnut extract against 1‐methyl‐4‐phenylpyridinium (MPP+) induced neurotoxicity in SH‐SY‐5Y cell lines.