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Time course of uptake, elimination, and tissue levels of (14C)DDT in wood-frog tadpoles.

Rana sylvatica tadpoles were treated with 0.001 and 0.003 ppm [14C]DDT (1,1,1 -trichloro-2,2-bis(p-chlorophenyl)ethane) at 15 and 21 °C and the time course of uptake and residue levels in several tissues of contaminated tadpoles were studied. By 24 h post treatment, highest concentrations of DDT were found in whole animals and in isolated tadpole tissues. After 80 h, DDT tissue levels began to diminish and fall slowly throughout the duration of the experiment. Liver and fat were the main sites for pesticide deposition. Tadpoles treated at 15 °C retained higher tissue levels of DDT for longer periods, i.e., they lost DDT more slowly than tadpoles at 21 °C.