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Quantitative determination of phenol in phenolated calamine lotion USP.

A method for the quantitative analysis of phenol in phenolated calamine lotion USP is described. The method is based on spectrophotometrically measuring the color produced by reacting phenol with either ferric chloride or ferric nitrate. Beer's law is followed. The effect of ferric-ion concentration on the sensitivity of the assay method is reported.