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Review: glucosamine and chondroitin improve outcomes in osteoarthritis, but the magnitude of effect is unclear

Data sources Studies were identified by searching Medline (1966 to June 1999) and the Cochrane Controlled Trials Register and reviewing bibliographies of reviews and manuscripts. Meeting abstracts published in supplements of Arthritis and Rheumatism, the British Journal of Rheumatology, and Osteoarthritis and Cartilage (1978–98) were handsearched. Authors, content experts, and drug manufacturers were contacted.