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[Pathophysiological damage to the kidney due to temporary ischemia and measures to avoid these changes (author's transl)].

The efficacy of the so-called 'hyperosmolar kidney preservation' is proved experimentally and clinically with respect to protecting the kidney from the otherwise lethal effect of protracted periods of warm ischemia. Furthermore, the protective effect of various pharmacologic agents against 2 and 3 h of normothermic ischemia is investigated and the pathophysiology of renal ischemic damage is pointed out.