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Can do’ versus ‘do do’: a novel concept in patients with COPD

Introduction: Impaired physical performance (PP) and low habitual physical activity (PA) are common features of people with COPD. Recently, a conceptual framework was published in which PP and PA represent associated but separate domains of physical function in the elderly. The question is whether this framework might be applicable as an aid in the understanding of physical functioning impairment in patients with COPD. Aims: The current study had two aims: 1) to determine the distribution of people with COPD over the PP-PA quadrants; and 2) to explore whether differences exist in clinical characteristics between the PP-PA quadrants. Method: PP was measured with a six-minute walk distance (6MWD) and PA was objectively assessed with an accelerometer. In addition, patient- and health status characteristics were systematically acquired. Patients were mapped using a quadrant based on their PP and PA into mutually exclusive categories: I) Low PP (6MWD Results: A total of 662 COPD were included in this study. Distribution over the quadrants was as follow: I=39%, II=19%, III=16%, IV=26%. Statistically significantly differences were found across the quadrants, among others, for age, FEV1, BMI, exacerbation frequency Conclusion: This study shows that COPD patients could be distributed over the PP-PA quadrant and that significant differences were found in clinical characteristics across these quadrants