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A randomized study comparing timolol and methyldopa in hospital treatment of puerperal hypertension

Summary. Treatment of puerperal hypertension (diastolic blood pressure 95–105 mm Hg) with methyldopa 750–3000 mg/day was compared with treatment with timolol 15–60 mg/day in a random trial of 80 patients. Within these dose ranges and over the period studied (9 days) both drugs appeared equally effective. Therefore, in the treatment of puerperal hypertension, timolol could be considered as a suitable alternative to methyldopa.