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Fat Tissue Transfer: Is It Useful? An in Vitro Study

Objective: This study aimed to establish in vivo adipose tissue, autologous transplantation of preadipocytes and adipocytes amplified in rat adipose culture suspensions and to compare histological features, adipose tissue formation and permanent volume following autologous transfer. Materials and Methods: There were 32 rats in the study divided into 4 groups. Adipocyte cell suspensions were injected into the scapular and evaluated 4, 8, 12, and 24 weeks later for groups I, II, III, and IV, respectively. Histological and volumetric changes were detected. Results: Although fatty tissue volume increased with time, there was no significant difference was between the groups. Histological scores were not different between groups (p>0.05). Conclusion: In our study, the formation of fatty tissue in healthy appearance was observed in a similar manner after autologous transplantation of the preadipocytes and adipocyte cells in the culture. In the future, we believe that the preadipocyte cell suspension can be transplanted in cell culture and can be transferred autologous to fill the soft tissue defect in the same patient.