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Complementary roles of Pseudomonas aeruginosa condensins in global chromosome organization

Condensins play a crucial role in global chromosome maintenance and organization in all forms of life. In bacteria, condensins contribute to proper resolution and segregation of sister chromatids following replication. Atypically, Pseudomonas aeruginosa strain PAO1 expresses two condensins, the canonical SMC‐ScpAB complex and the unconventional MksBEF. These two proteins belong to two different super‐families of condensins. Here we investigated the roles of SMC‐ScpAB and MksBEF in chromosome segregation of PAO1.