{'fraction_non_alphanumeric': 0.03172205438066465, 'fraction_numerical': 0.046450151057401814, 'mean_word_length': 5.232941176470589, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
S0638 Clinical Outcomes for COVID-19 Patients Admitted With Gastrointestinal Bleeding: A Descriptive Study

INTRODUCTION: COVID-19 pandemic has changed many hospital protocols, resulting in a massive reorganization of resources, human power and hospital operations Limited information is available on the impact of the COVID-19 pandemic on outcomes of patients who had tested positive for the SARS-CoV-2 and were admitted with gastrointestinal bleeding (GIB) METHODS: We performed a retrospective single-center study at a large tertiary care hospital All index admissions of adult patients with confirmed COVID-19 between March 1 and May 15, 2020 and gastroenterology consultation for overt GIB were included Data on baseline characteristics and clinical outcomes were collected during manual chart review Outcomes were 30-day mortality as well as the need of endoscopic, radiological and surgical interventions RESULTS: A total of 67 patients were included (mean age 69 12 years, SD 11 14 years), of which 45 (76 20%) were male and 35 (52 20%) were African American 44 80% and 35 80% of patients were on aspirin and anticoagulation respectively The majority of patients (77 6%) presented with upper GIB symptoms as follows (32 melena, 12 hematemesis/coffee ground emesis, 5 melena and hematochezia, 2 massive hematochezia and 1 bleeding from PEG tube) 3 patients had a hemorrhagic shock The Glasgow-Blatchford score (GBS) on presentation ranged between 0-15 (mean 9 57, SD 3 882) and pre-endoscopic Rockall score ranged between 0 and 7 (mean 3 71, SD 1 473) A total of 36 patients were admitted to the ICU during hospitalization, of which 24 patients required vasopressors and 32 patients were intubated Apart from supportive and medical therapy for GIB, further interventions were as follows: endoscopic evaluation: 18 patients (16 EGDs, 1 colonoscopy, 1 EGD 1 colonoscopy), IR embolization: 2 patients and surgical intervention: 1 patient Eventually, 13 patients died, mostly due to respiratory failure and septic shock Patients with higher GBS were more likely to undergo an endoscopic intervention (P &lt; 0 001) and to receive packed RBC transfusion (P &lt; 0 001) Patients who underwent endoscopy were more likely to be on anticoagulation (P 0 041), more likely to present with melena (P 0 024) and to be more remote after the COVID-19 infection (P &lt; 0 001) CONCLUSION: Although the threshold to perform an endoscopic evaluation or other invasive interventions for GIB was higher in COVID-19 positive patients, an evaluation by gastroenterology is still required Patients with higher GBS were more likely to require an active intervention