{'fraction_non_alphanumeric': 0.05378568473314026, 'fraction_numerical': 0.04426975589573852, 'mean_word_length': 4.985148514851486, 'pattern_counts': {'":': 0, '<': 1, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Abstract 343: Association Between Hospital Arrival Time and Outcomes in Patients With Out-of-Hospital Cardiac Arrest Due to Acute Myocardial Infarction: JAAM-OHCA Study Group


 Background:
 Whether arrival time is associated with in-hospital managements and outcomes in patients out-of-cardiac arrest (OHCA) due to acute myocardial infarction (AMI) is still unclear.
 
 
 Methods:
 We conducted a multi-institutional, observational study (JAAM-OHCA study) of OHCA from June 2014 through December 2015 in Japan. The primary exposure was hospital arrival time divided into three groups, defining weekday regular time as 8:00 AM to 4:59 PM, weekday night time as 5:00PM to 7:59AM, and weekends/holidays as Saturday, Sunday and holidays. The outcome measures were in-hospital managements (i.e., percutaneous coronary intervention [PCI], intra-aortic balloon pump [IABP], extracorporeal cardiopulmonary resuscitation [ECPR], and target temperature management [TTM]), and neurologically intact survival at 30-day. To determine the associations of hospital arrival time with these outcomes, we constructed logistic regression models adjusting for patient characteristics, out-of-hospital care and in-hospital care, with generalized estimating equations accounting for patient clustering within hospitals.
 
 
 Results:
 We recruited 13,491 patients with OHCA. Of these, 852 had return of spontaneous circulation and was diagnosed as AMI; n=299 arrived during weekday regular time; n=265 arrived during weekday night time; n=288 arrived during weekends or holidays. Finally, a total of 219 (25.7%) OHCA patients had neurologically intact survival at 30-day. The rates of in-hospital management were not different among the three groups except IABP use (P<0.01). Compared to patients arrived during weekday regular time, neurologically intact survival rate at 30-day was not significantly different in patients arrived during weekday night time and weekends/holiday (26.1% [78 of 299] in weekday regular time group, 22.6% [60 of 265] in weekday night time group, and 28.1% [81 of 288] in weekends/holidays group) with corresponding adjusted odds ratios of 0.80 (95% confidence interval [CI] 0.45-1.40; P=0.43) and 0.96 (95% CI 0.57-1.63; P=0.89).
 
 
 Conclusion:
 In this observational study of adult patients with OHCA due to AMI, in-hospital managements and outcomes were not differed across hospital arrival time groups.
