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Hypomagnesemia in Type 2 Diabetic Nephropathy : A Novel Predictor of End-Stage Renal Disease

RESEARCH DESIGN AND METHODSdThis retrospective cohort study included 455 chronic kidney disease (CKD) patients (144 with type 2 diabetic nephropathy and 311 with nondiabetic CKD) who were hospitalized at Osaka General Medical Center for a CKD educational program between April 2001 and December 2007. The primary outcome was progression to renal replacement therapy. Participants were categorized based on serum Mg level into Low-Mg (serum Mg level #1.8 mg/dL) and High-Mg (serum Mg level .1.8 mg/dL) groups with the previously published normal lower limit chosen as the cutoff point.