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DNA sequence of the transposase gene of the class II transposon, Tn3926.

The DNA sequence of the Tn3926 tnpA gene (shown) is 80X similar to that of Tn2l (1). The encoded transposase is 991 amino acids long and shows 87X positional identity to the Tn2l transposase. The Tn3926 transposase differs from that of Tn2l in being unable to mediate efficient one-ended transposition (1, 3), and unable to complement tnpA- mutants of Tn50 and Tnl721 (2, 4). Comparison of the Tn3926 and Tn2l transposases indicates those regions of the proteins responsible for these differences.