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Design and demonstration of the transmission, reflection, and intensity (TRI)-analyzer instrument for portable spectroscopy

In this paper, a smartphone-integrated optical cradle is designed, developed and used to perform three modalities of optical biosensing including absorptive transmission, photonic-resonance based reflection, and fluorescence intensity. Proof-of-concept demonstration of two off-the-shelf diagnostic tests for maternal and child health biomarkers is completed and compared with a traditional laboratory instrument.