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Echocardiographic comparison between prenalterol and dobutamine.

Prenalterol, a new cardioselective beta 1-adrenoceptor agonist, was compared with the beta-stimulator dobutamine by computer-assisted echocardiography. Prenalterol decreased preload, increased heart rate and induced an increase in contractility for a longer time in comparison with dobutamine. The small influence on blood pressure and afterload indicates selective beta 1-receptor-effect by a result of slight changes in the peripheral vascular resistance.