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[Myxoma extending from the superior vena cava to the right pulmonary artery].

Primary cardiac tumors are very uncommon. They include the myxoma, which constitutes between 42% and 77% of these lesions. In contrast, metastatic cardiac tumors are more common, and their incidence in autopsies of patients with generalized neoplasms ranges between 10% and 20%. Melanoma is the tumor that most frequently produces cardiac metastases, followed by malignant germ cell tumor (in a series of 100 necropsies in patients with this tumor, 38% presented cardiac metastases). We report the case of a 38-year-old man who, in 2003, was diagnosed as having a testicular germ cell tumor, with mediastinal, pulmonary and retroperitoneal spread. He underwent right orchiectomy and chemotherapy, followed by sequential resection of the retroperitoneal, mediastinal, and pulmonary lesions. Although follow-up examinations indicated that he was disease-free, central venous access (Port-A-Cath) was maintained. In August 2004, an echocardiogram was carried out when auscultation of a murmur revealed a mass originating in the superior vena cava. It initially presented a tubular morphology, but would later acquire a cluster form with multiple protuberances. It was mobile and extended through the right atrium and ventricle, and pulmonary artery and its right branch, where it ended. Chest computed tomography showed important filling defects in right heart chambers. As the presence of thrombi was suspected, treatment with sodium heparin was begun. Lung scintigraphy was indicative of embolisms in the middle and lower lobes of the right lung. Despite the anticoagulant therapy, the echocardiographic images remained the same and, thus, the decision was made to perform surgery. The lesion was a large, multipedicled tumor mass originating in superior vena cava, with no endocardial adhesions in atrium or ventricle, and with necrotic zones along its entire length. On palpation, it appeared to originate in an inaccessible region above the azygos vein. The lesion was resected in its entirety with the exception of residual pedicle at the base (Figure 1). Another implantation site, measuring 3×3 cm, observed on the anterior aspect of right ventricle was biopsied. The pathological diagnosis was myxoma. Seventeen months later, echocardiograms again revealed progressive growth of the tumor, with a large vegetative mass originating in superior vena cava extending through the right atrium and ventricle, passing through the pulmonary valve and reaching the main pulmonary artery. The decision was made to perform surgery yet again and a yellowish, clustered, multinodular tumor originating in the brachiocephalic trunk was found. It was not attached to the endocardium and was completely resected. The pathological examination involved calretinin immunolabeling, which proved to be positive, resulting in a diagnosis of villous myxoma (Figure 2). This case is of interest because of the rarity of the tumor itself, which had a vermiform shape from its onset in the superior vena cava, reached the right chambers, passed through them without interruption, widened in the right atrium and right ventricle, narrowed when it passed through the respective tricuspid and pulmonary valves, and ended in the pulmonary LETTERS TO THE EDITOR