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The influence of nutrition on neural and behavioral development. I. Critical review of some data on the growth of the body and the brain following dietary deprivation during gestation and lactation.

The scanty data available on the effects of undernutrition during gestation and lactation upon neural development in man are reviewed briefly. This review is followed by a description of the various techniques that have been employed for the experimental undernutrition of laboratory animals. Then a detailed review is given of the effects of dietary deprivation during gestation, lactation, after weaning, and in adulthood upon the development of the nervous system and its different parts in a variety of mammalian species, with special emphasis on the rat. Finally, in a programmatic statement, the developmental phases during which undernutrition can be produced experimentally are related to critical stages or vulnerable periods of brain development.