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[Afferent and central mechanisms of the osmoregulating reflex from the liver following hypothalamic deafferentation].

In anesthetized cats, 52 units of the hypothalamic supraoptic nuclei out of 65 retained the ability to respond to the osmotic stimulation after dissection of the brain stem (cerveau isolé). Administration of 1.0 ml 5% NaCl solution into the v. porta decreased the firing rate in 9 units and increased it in 43 units. The latency and the maximum reaction time were 30-100 sec and 2-6 min, resp. The data obtained suggest a humoral link in the reflex from the liver osmoreceptors.