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Resistance of stem‐like cells from neuroblastoma cell lines to commonly used chemotherapeutic agents

Cancer stem cell theory suggests that the presence of tumor initiating stem‐like cells in cancers may be responsible for cancer progression and relapse. CD133 cell surface maker expression has been used to identify stem‐like cells in cancer cell lines. Our goal was to identify such cells in neuroblastoma cell lines and to study the cytotoxicity of common anticancer drugs for those cells.