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Concentration of noradrenaline in pial vessels, choroid plexus, and iris during two weeks after sympathetic ganglionectomy or decentralization.

Changes in the noradrenaline concentration of the sympathetically innervated pial vessels, choroid plexuses, and irides of the rabbit were measured fluorometrically at various periods during the first 2 weeks after pre- or postganglionic denemation (decentralization or excision of the superior cervical ganglia). The noradrenaline values fell to negligible amounts within 2 days after ganglionectomy in all organs, probably somewhat slower in choroid plexuses. After decentralization the noradrenaline level increased in the pial vessels, whereas in the choroid plexuses and iris it initially decreased followed by normalization. The fall occurred somewhat later in the iris. It is suggested that the results of the denervation experiments reflects the presence of functionally different types of sympathetic neurons in one and the same ganglion.