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Grading follicular lymphomas in fine‐needle aspiration biopsies

The World Health Organization (WHO) recommends a 3‐tier grading system (Grades 1–3) for follicular lymphomas (FLs) based on the absolute number of centroblasts per high‐power microscopic field (HPF) in 10 neoplastic follicles. Grades 1 and 2 FL are still managed as indolent FLs, whereas Grade 3 FL is thought to behave more aggressively. In this study, the feasibility of grading FL using ThinPrep (TP) slides and flow cytometry (FC) was evaluated.