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Antihypertensive effects of exercise among those with resistant hypertension.

Dimeo et al1 tested the hypothesis that aerobic exercise training reduces ambulatory blood pressure (ABP) among individuals with resistant hypertension and found that daytime systolic (6 mm Hg) and diastolic (3 mm Hg) ABPs were reduced after an 8- to 12-week aerobic exercise training program. Their findings indicate that exercise is effective antihypertensive therapy in a clinical population that is not responsive to drug therapy. Nonetheless, they should be interpreted with caution for the reasons below.

Daytime ABP was the primary outcome. A complete description of the ABP methods including the timing when ABP was taken and procedures for handling missing …