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Malignant Triton Tumor of the Ethmoid Sinus and Nasal Cavity

In 1932, Masson first described a lesion that consisted of a malignant schwannoma with rhabdomyoblastic differentiation. Subsequently, Woodruff et al coined the term "Malignant Triton Tumor" (MTT) to indicate such a neoplasm. The name refers to Locatelli's experiment in which a sciatic nerve implanted onto the back of a Triton salamander caused the growth of a supernumerary limb made up of neural and muscular tissue. Approximately 15% of MTTs contain additional mesenchymal or epithelial elements and are therefore designated as having "pluridirectional differentiation."