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Cardiac Baroreflex Sensitivity during Mild Hypercapnia Following Acute Beetroot Juice Consumption

Patients with obstructive sleep apnea often exhibit augmented arterial carbon dioxide tension (CO2) and autonomic dysfunction, which result in increased sympathetic activity and reduced baroreflex sensitivity. Beetroot juice (BRJ) is a popular nutraceutical that decreases resting sympathetic nerve activity and improves vascular function. However, the effects of acute BRJ consumption on cardiac baroreflex sensitivity (cBRS) in healthy individuals with elevated arterial CO2 is unknown.