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Promising effects of oxytocin on social and food‐related behaviour in young children with Prader–Willi syndrome: a randomized, double‐blind, controlled crossover trial

Prader–Willi syndrome (PWS) is known for hyperphagia with impaired satiety and a specific behavioural phenotype with stubbornness, temper tantrums, manipulative and controlling behaviour and obsessive–compulsive features. PWS is associated with hypothalamic and oxytocinergic dysfunction. In humans without PWS, intranasal oxytocin administration had positive effects on social and eating behaviour, and weight balance.