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[Clinical aspects of the pathophysiology of HIV infection. III. Principles of therapy].

The author analyzes different possible therapeutic approaches to HIV infection in different clinical stages. He draws attention to the fact that antiretroviral therapy has always also a certain immunomodulating effect and vice versa. It is in particular necessary to pay attention to the fact that therapeutic activation of the immune system may be associated with undesirable activation of HIV replication. After giving an account of different theoretical possibilities of the therapeutic influencing of HIV infection the author analyzes hitherto assembled experience with the only treatment which can stabilize the condition in clinical practice for a certain period, i. e. administration of azidothymidine (AZT).