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Gastric perforation associated with indomethacin therapy in a pre‐term infant.

This is a case report of a pre‐term infant who developed a gastric perforation fifteen hours after receiving oral indomethacin treatment for the pharmacological closure of a patent ductus arteriosus. This observation of a possible causal relationship between indomethacin and gastric perforation reaffirms the need for caution when using this drug in pre‐term infants.