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A SERRS-active bead/microelectromagnet system for small-scale sensitive molecular identification and quantitation.

How do you catch and identify a molecule in a very dilute solution? The question is important for the detection of trace amounts of such molecules as explosives, drugs, and biomolecules. Here we use a specifically designed microelectromagnet and surface-enhanced resonance Raman microspectroscopy (see figure) to provide an answer to this question, advancing a technique that has advantages over other current technologies.