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Gastrointestinal Symptoms in Korean Adults with Depressive Symptoms

Background/Objectives: Recent research has revealed gastrointestinal (GI) symptoms are one of the most prominent clinical manifestations of depression. The goal of this study is to find out the link between GI symptoms and depressive symptoms in a population of individuals who have not yet diagnosed with depression. 
Methods: A total of 179 research participants were recruited offline and online, with 134 in the normal group and 45 in the group with depressive symptoms. The subjects' GI function and symptoms were evaluated with a validated GI questionnaire, and depressive symptoms were assessed with the Hamilton Depression Rating Scale (HDRS). The statistics were examined using SPSS version 26. 
Results: Those with depressive symptoms were significantly more likely to be single, have a higher level of education, and engage in significantly fewer physical activities than those in the control group. In addition, the depressive symptom group experienced significantly more stomach discomfort, heartburn, regurgitation, abdominal rumbling, bloating, empty feeling, nausea, vomiting, loss of appetite, postprandial fullness, worsening stool issues, and GI pain compared to the normal group. 
Conclusion/Implications: In this study, we discovered an intriguing lifestyle phenotype within the depressive symptom group as well as a link between depressive symptoms and GI symptoms. This research indicates that psychological variables play a substantial impact in the presence of gastrointestinal problems.