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Dissociation between In-111 chloride and Tc-99m colloid bone marrow scintigraphy in refractory anemia with excess blasts.

Marked renal uptake of ln-111 was found in a patient with refractory anemia with excess blasts (RAEB). A 46-yearold man was admitted to the hospital with severe anemia and splenomegaly. Bone marrow scintigraphy was performed using ln-111 chloride and Tc-99m tin colloid, and there was a strikingly different distribution between these two agents. A bone marrow aspirate from the sternum revealed myeloid dominant hypercellularity with excess blasts, and he was finally diagnosed as having RAEB. Repeated blood transfusions resulting in a saturation of transferrin seemed to be a cause of the dissociation.