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Analytical study on bioheat transfer problems with spatial or transient heating on skin surface or inside biological bodies.

Several closed form analytical solutions to the bioheat transfer problems with space or transient heating on skin surface or inside biological bodies were obtained using Green's function method. The solutions were applied to study several selected typical bioheat transfer processes, which are often encountered in cancer hyperthermia, laser surgery, thermal comfort analysis, and tissue thermal parameter estimation. Thus a straightforward way to quantitatively interpret the temperature behavior of living tissues subject to constant, sinusoidal, step, point or stochastic heatings etc. both in volume and on boundary were established. Further solution to the three-dimensional bioheat transfer problems was also given to illustrate the versatility of the present method. Implementations of this study to the practical problems were addressed.