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Cancer of the Paranasal sinuses and nasal cavities Part I. Clinical features

Many publications have appeared on this subject over the last 20-30 years relating both to details of treatment and to end-results. For the most part there has been little substantial improvement in survival for patients with malignant disease of the region. Underlying the problem there has also been little change in treatment techniques following the introduction of telecobalt irradiation and the recognized value of combining this in a planned sequence with radical surgery. However, the advent of effective cytotoxic chemotherapy protocols used prior to conventional modalities, and the development of extended resection techniques to include parts of the skull base may give more hope for future results.