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Regeneration of ankylosed teeth in the adult frog premaxilla.

The relationship between the ankylosed amphibian tooth and regeneration of a jaw segment was studied. A section of the premaxilla was removed in 95 young leopard frogs. Subsequent would healing was observed at intervals of 0-180 days. The dental lamina formed new teeth and by 90 days, teeth in varying stages of development could be seen extending across the wound segment. Teeth within the wound grew to normal size and shape and were replaced by their successors without support of underlying jaw bone which grew in later and often was incomplete.