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IN OTHER JOURNALS

In post pubertal women with moderate to severe acne and hirsutism, hyperandrogenemia is often suspected and maybe associated with polycystic ovarian syndrome (PCOS). This study assesses the ovarian morphology and presence of PCOS in patients with mild acne, as defined by the International Consensus Conference, with or without hirsutism. 111 nulligravid caucasion women between 18 and 35 years were included in the study which assessed serum androgens and pelvic ultrasonography. The latter was used to assess ovarian volume, presence of polycystic ovary and stromal thickness in both groups. No patients in either the acne or control group had received any hormonal therapy for three months prior to their first assessment and they were matched for age and body mass index. 52 women with mild acne were compared with 59 women with no history of menstrual irregularity and no acne. An assessment of excess body and facial terminal hair growth was also made in all patients allowing for a hirsutism score. Only serum levels of total testosterone were statistically higher in the acne group compared to controls whereas dehydroepiandrosterone sulphate and 17hydroxyprogesterone levels were similar. All measures of ovarian volume were significantly higher in the acne group as was the incidence of polycystic ovary (50 % vs. 22%) and hirsutism (51% vs. 13.6%). This study suggests that even mild acne may be a sign of underlying PCOS, particularly if hirsutism is associated.