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[Isolation and identification of antibiotics produced by Actinoplanes brasiliensis INA 3802].

In the screening programme for new antibiotics produced by Actinoplanes brasiliensis an antibiotic complex A-3802 was isolated and studied in detail. It had a marked therapeutic effect in the treatment of staphylococcal sepsis in albino mice and was low toxic. Two components of the complex i.e. A-3802-IV-3 and A-3802-IV-4 were identified with the lantibiotics actagardin and its diamide disulfoxide. Antibiotics A-3802-V-4 and A-3802-VI-7 were shown to be new antibiotics of the same group.