{'fraction_non_alphanumeric': 0.02676864244741874, 'fraction_numerical': 0.032504780114722756, 'mean_word_length': 4.057971014492754, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Exposure of herpes simplex virus type 1 and its host cells to cigarette smoke in vitro.

A 1.0 ml suspension of herpes simplex virus type 1 in tissue culture growth medium was exposed at 37 degrees C to eight puffs of smoke from one cigarette. Each puff consisted of 25.0 ml of mainstream smoke, and was delivered by a mechanical smoking apparatus. At 0, 15 and 60 min after exposure the virus was assayed for infectivity using HEp-2 cells as the host. Neither filter nor non-filter cigarette smoke affected the infectivity of the virus, or the viability of HEp-2 cells treated with smoke in a manner similar to the virus. The filter cigarette contained 19.0 mg of tar and 1.2 mg of nicotine, and the non-filter cigarette had 23.0 mg of tar and 1.4 mg of nicotine. Smoke from four non-filter cigarettes delivered over a 4 h period caused a 4-log10 drop in virus infectivity titre, and smoke from four filter cigarettes caused more than a 1-log10 drop in titre. Smoke from four non-filter or filter cigarettes was highly cytocidal for HEp-2 cells.