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A landmark contribution to poultry science--a possible mode of action of sulfamethazine on the reproductive system of Leghorn cockerels.

The paper "The effect of sulfamethazine feeding on the thyroids, combs and testes of Single Comb White Leghorn cockerels" was published early in the career of Ari van Tienhoven when he was an assistant professor. The current manuscript pays tribute to that study submitted to the journal, Poultry Science, over 5 decades ago. In addition, the review examines the academic lineage of van Tienhoven to show that his line of descent produced several scientists who have contributed significantly to the success of the Poultry Science Association in the discipline of neuroendocrinology and avian physiology during most of its first 100 yr. In a quiet, unassuming manner, van Tienhoven has had a major effect on basic research addressing reproductive endocrinology in vertebrates, particularly in the domestic fowl, Gallus gallus. Biographical information, his academic pedigree, students produced, research areas pursued, and the landmark contribution selected for review are highlighted. A link to an electronic archive of a recorded interview with van Tienhoven in preparation for the symposium can be accessed using the link given in the first footnote.