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Immediate type reactions in pathogenesis of infectious allergy

The bacterial allergens available in our country are designed to detect only delayed-type hypersensitivity. However, it is known that both delayed- and immediate-type hypersensitivity reactions may be involved in the pathogenesis of infectious-allergic diseases. A number of authors have shown the presence of specific reactive antibodies of the IgE class to bacteria in patients with infectious allergies. There is evidence of elevated levels of IgE in patients with infectious-allergic bronchial asthma, pyoderma and microbial eczema. Immediate reactions in infectious allergies may occur with the formation of circulating immune complexes.