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Genetic basis of glaucomas

Glaucoma is characterized by a progressive loss of retinal ganglion cells. The exact cause of the glaucoma is still unknown.The glaucoma is a multifactorial disease and affected by multiple genetic and environmental factors. Ethnic differences in the prevalence of glaucoma and positive family history support the inheritance of glaucoma. There is evidence showing that genetic factors may play an important role in the pathogenesis of the disease. Here we aim to emphasize the genetic basis of glaucoma.