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Melatonin as a Chemical Substance or as Phytomelatonin Rich-Extracts for Use as Plant Protector and/or Biostimulant in Accordance with EC Legislation

Melatonin (N-acetyl-5-methoxytryptamine) is a ubiquitous molecule present in animals and plants, and also in bacteria and fungi. In plants, it has an important regulatory and protective role in the face of different stress situations in which it can be involved, mainly due to its immobility. Both in the presence of biotic and abiotic stressors, melatonin exerts protective action in which, through significant changes in gene expression, it activates a stress tolerance response. Its anti-stress role, along with other outstanding functions, suggests its possible use in active agricultural management. This review establishes considerations that are necessary for its possible authorization. The particular characteristics of this substance and its categorization as plant biostimulant are discussed, and also the different legal aspects within the framework of the European Community. The advantages and disadvantages are also described of two of its possible applications, as a plant protector or biostimulant, in accordance with legal provisions.