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The effects of multiple passes on the epidermal thermal damage pattern in nonablative fractional resurfacing

Nonablative fractional resurfacing is a concept of cutaneous re‐modeling whereby laser‐induced microscopic treatment zones (MTZs) are surrounded by normal viable tissue. Such thermal damage pattern with a small diameter of individual lesions allows fast re‐epithelialization with minimal side effects. The purpose of this in vitro study was to determine the fraction of thermal injury per unit surface area (fill factor) and lesion size in relation to pulse energy and number of passes.