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Management of granulomatous mastitis

Granulomatous mastitis (GM) is an uncommon mild inflammatory breast disorder that primarily affects the people who had the breastfeeding experience. However, the inflammation related to wound response, metabolic or hormonal mechanisms, autoimmunity and a Corynebacterium kroppenstedtii infection are concerned. Etiopathogenesis is an unknown issue carrying the symptoms of pain, weight, hyperemia and inflammation. Etiopathogenesis is also prolonged and the clinical appearance is capable of imitating bacterial mastitis or inflammatory carcinoma. Histopathology is used for its diagnosis. The biopsy reveals granulomatous development coupled with scattered invasion of giant multi-nucleated cells, plasma cells and histiocytic epithelium cells. Mammography, ultrasound and “Magnetic Resonance Imaging” are not specific methods, however, can be performed to exclude other pathologies through the ultrasound and mammography. GM management is problematic due to lack of evidence even randomized controlled trials. Majority of clinicians used a therapy plan beginning with antibiotics and corticosteroids in Western developed world accompanied by constant steroid care and procedure of patients with chronic symptoms requiring accurate cares. Up to now, there is no proof over the immunotherapy function that needs further knowledge about the rare disorder. Key word: granulomatous mastitis (GM), Idiopathic granulomatous mastitis (IGM) How to cite this article: Aodyshow SK, Saeed MF, Hasan AM (2020): Management of granulomatous mastitis, Ann Trop Med & Public Health; 23(S24): SP232446. DOI: http://doi.org/10.36295/ASRO.2020.232446