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SEX STEROID HORMONE LEVELS IN PLASMA FOLLOWING INTRA–AMNIOTIC INJECTION OF UREA AND PROSTAGLANDIN E2

Plasma progesterone, 17‐hydroxyprogesterone, oestrone, oestradiol and oestriol were determined before and after the intra‐amniotic injection of urea and prostaglandin E2 for mid‐trimester abortion. A general decline in hormone levels resulted following the injection and preceding abortion. The decreases in plasma progesterone and oestriol were most marked, a significant fall resulting one hour after injection.