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Pigtailed macaques (Macaca nemestrina) with trisomy X manifest physical and mental retardation.

Three pigtailed macaques (Macaca nemestrina) from a nursery population were predicted to be genetically abnormal based on observations of anatomical and behavioral development. All three exhibited delays in skeletal, visual, intellectual, and social development, suggesting a chromosomal syndrome. Karyotypes showed that two animals were XXX females, and the third was a mosaic XX/XXX female.