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Butyryl‐ and acetyl‐cholinesterase inhibitory activities in essential oils of Salvia species and their constituents

Extracts of Salvia (sage) species have been reported to have cholinergic activities relevant to the treatment of Alzheimer's disease. A lack of information on the inhibition of the enzyme butyrylcholinesterase, also considered to be a target in the treatment of the disease, prompted this in vitro investigation of the essential oils of S. fruticosa, S. lavandulaefolia, S. ofﬁcinalis and S. ofﬁcinalis var. purpurea for anti‐butyrylcholinesterase activity.