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Herpes-zoster myelitis treated successfully with vidarabine.

Skin eruptions may occur in up to 190" of patients receiving cimetidine, an incidence marginally higher than that found in patients receiving placebo.' The eruption most commonly described is mild, non-specific, erythematous, and maculopapular. Severe reactions, including bullous erythema multiforme have, however, been reported.2 Erythema annulare centrifugum is a pruritic, erythematous eruption beginning as a papule and progressively enlarging at the margin while clearing at the centre. It has been reported occasionally to be associated with underlying malignancy, dermatophyte infection, or drug treatment, though usually no cause is found and the lesions eventually disappear spontaneously after months or years.3 We describe a patient in whom erythema annulare centrifugum complicated long-term cimetidine treatment.