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STUDY OF INSULIN RESISTANCE AND THYROID PROFILE IN WOMEN WITH
SPONTANEOUS ABORTIONS

Thyroid dysfunction and insulin resistance are important endocrinological causes of spontaneous abortions. This study is resistancewith
spontaneous abortions Thyroid dysfunction and Insulin resistance are common endocrinological causes of abortions.The present study is a case
control study where 75 patients with spontaneous abortions below 20 weeks were taken as cases and 75 patients with normal on going pregnancy
without previous history of miscarriage were taken as controls. Thyroid Function Tests (Free T3 ,Free T4,TSH) ,Oral Glucose Tolerance Test
following 75 mg glucose load were done in cases and controls. Fasting glucose and insulin levels were measured and Insulin resistance was
calculated using homeostatic model assessment method (HOMA- IR).Free T3 levels were signicantly lower and TSH levels were signicantly
higher in study group indicating the presence of hypothyroidism in the abortus group. The HOMA-IR insulin resistance scores were apparently
higher in the study group than in the controls, but it was not statistically signicant.