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The effect of exercise on intraocular pressure. II. Rabbits.

Intraocular pressure was found to decrease after treadmill exercise in rabbits. This fall was associated with an increase in plasma osmolarity and blood lactate and a decrease in blood pH. The alteration in intraocular pressure was reproduced by consecutive injections of hyperosmotic sodium lactate and isosmotic hydrochloric acid in amounts to duplicate the rise in plasma osmolarity and the fall in blood pH induced by exercise.