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Correlation of FRAX Risk Score and Severity in Osteoporotic Vertebral Fracture

Objectives: To identify the correlation between FRAX risk score and severity of osteoporotic vertebral fracture Methods: The study subjects were 214 in-patients who had osteoporotic vertebral fracture. The subjects were divided into 2 groups according to whether or not they had a BMD score (BMD, non-BMD group). Fracture severity index was calculated from lateral vertebral x-ray film with Genant's semiquantitive method. The correlation between FRAX risk score and fracture severity index were analyzed. Results: Significant correlation was detected between FRAX risk score (major osteoporotic & hip fracture) and fracture severity index in the BMD group (r=0.463, p<0.001, r=0.446, p<0.001) as well as between FRAX risk score and BMD (r=-0.322, p<0.001). There was no correlation in the non-BMD group Conclusions: This study demonstrates a correlation between FRAX risk score and osteoporotic vertebral fracture severity in BMD group.