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WORK OF BREATHING

The work of breathing in newborn infants with pulmonary disease is considered to be markedly increased (9, 11, 14, 18). Cook et al. (11) commented from their measurements of the work of breathing in two infants with respiratory distress that their results supported “the clinical impression that these infants frequently die of exhaustion”, and that “therapy should, at least in part, be directed toward support of respiratory efforts”. If this is the case measurement of the work of breathing might be of clinical value, helpful in choice of therapy and an important parameter for monitoring in diseased infants. However, to date only a limited number of observations have been reported on this topic.