{'fraction_non_alphanumeric': 0.02823920265780731, 'fraction_numerical': 0.0016611295681063123, 'mean_word_length': 4.9068627450980395, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Long-term non-progressors, survivors and HIV positives.


 In cohort studies of HIV infection, approximately five percent of participants are long-term non-progressors--those who have been infected for over ten years and remain asymptomatic, have normal and stable immunologic profiles, and have not received any anti-HIV treatments. Researchers continue to study this group with the hope that it may provide insights into potential therapies and vaccines that may prevent primary HIV infection and enable HIV positive people to become or remain long-term non-progressors. Recent findings are consistent with numerous other reports which indicate that HIV-1 disease progression is driven by an increasing viral burden. Researchers found that in long-term non-progressors, the viral load is low but viral replication persists. Lymph node architecture and immune function appear to remain intact. Researchers also focus on genetic markers, such as the nef gene of HIV--which is required for the development of AIDS after infection with SIV in the rhesus monkey AIDS model. In addition, researchers continue to study CD8 cell anti-HIV factor (CAF), which appears to be a strong response in non-progressors.
