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1360: THE ASSOCIATION OF BODY MASS INDEX AND ACUTE KIDNEY INJURY IN LIVER TRANSPLANTATION RECIPIENTS

Critical Care Medicine • Volume 46 • Number 1 (Supplement) www.ccmjournal.org Learning Objectives: Liver transplantation (LT) is a complicated procedure with a high incidence of postoperative acute kidney injury (AKI). Previous literature indicates that even transient or mild post-LT AKI can result in critical situations, including prolonged intensive care unit or hospital stays and increased morbidity and mortality. Based on recent study demonstrating that lower body mass index (BMI) is an independent risk factor for deterioration of renal function, we hypothesized that lower BMI would negatively affect postoperative renal function. The aim of this retrospective study was to investigate the association of BMI and occurrence of AKI in LT recipients. Methods: The medical data of 213 patients who received LT surgery from January 2010 to August 2016 in a single university hospital setting was retrospectively collected and analyzed. Patients were classified to either underweight (BMI < 20 kg/m2) or normal weight (20 ≤ BMI < 30 kg/m2) group. The demographic data, anesthetic methods, complications, and perioperative laboratory test values of each patient were assessed. Propensity analyses and logistic regression were performed to evaluate the association between BMI and post-LT AKI. Results: There was no significant difference in the occurrence of post-LT AKI between underweight and normal weight groups. The underweight group showed significantly longer hospital stay compared to that of the normal weight group (p = 0.02). Conclusions: BMI classification was neither a positive or negative predictor of postoperative AKI occurrence. However, patients with lower BMI demonstrated significantly longer hospital stay compared to their counterparts. Although our study was limited by its retrospective design, our observation suggests that lower BMI may play a role in post-LT AKI.