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Levels and Significance of Serum Adiponectin in Patients with Chronic HBV Infection at Different Clinical Stages

To analyze the serum APN levels of patients with chronic HBV infection in different clinical stages and their correlation with clinical laboratory examination indicators. A total of 120 HBV-infected patients are included in this study, including chronic HBV carriers, chronic hepatitis B (CHB) and compensated cirrhosis patients, 40 cases in each group, and 40 medical examinees as healthy controls. Compared with the healthy control group, the APN level in the chronic HBV infection group is significantly increased (p<0.05), and the APN level in the cirrhosis group is significantly increased compared with the other two groups (p<0.05). There is no significant difference between the chronic HBV carrier group and the CHB group. The ratio of people with high APN in the high DNA viral load group is higher (p = 0.002, χ2 = 9.143); the APN level of the liver cirrhosis group is significantly different from the non-cirrhosis group (P = 0.004, χ2 = 8.123). There is no significant correlation between APN level and ALT, AST and other indicators (P>, 0.05). High serum APN may be used as a marker for the diagnosis of HBV-infected liver cirrhosis.