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Gastrointestinal stromal tumor of the stomach (clinical case)

Gastrointestinal stromal tumors (GIST) are the most common malignant submucosal neoplasms of the gastrointestinal tract, with predominant localization in the stomach and small intestine. The disease pattern is the absence of specific clinical signs, at least a third of cases are detected during examinations or surgical interventions for other diseases or at an autopsy. The examination algorithm of patients with suspected GIST includes endoscopic and radiation diagnostic methods, including a number of high-tech and expensive techniques, such as endoscopic ultrasonography, computed tomography, immunohistochemical and molecular genetic methods for studying biopsy material. Only conducting a full set of examinations will allow timely diagnosis and choosing the optimal treatment tactics for the disease with a high risk of malignancy. The authors present their own clinical case of a patient, female, with GIST, which is of considerable interest to clinicians. The above clinical case represents a typical clinical and morphological picture of GIST. The disease onset occurred in a patient over the age of 60 years and proceeded under the guise of organic dyspepsia. In this case, the use of expensive high-tech techniques allowed to verify the diagnosis of GIST and refer the patient to surgical treatment. KEYWORDS: gastrointestinal stromal tumor, stomach tumor, endoscopic ultrasonography, immunohistochemistry, differential diagnosis. FOR CITATION: Skvortsova T.E., Oganezova I.A., Medvedeva O.I. et al. Gastrointestinal stromal tumor of the stomach (clinical case). Russian Medical Inquiry. 2021;5(6):433–437 (in Russ.). DOI: 10.32364/2587-6821-2021-5-6-433-437.