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Acute monocytic leukaemia in adults: treatment and prognosis in 99 cases

Acute monocytic leukaemia (AMoL) was diagnosed in 99 adults, aged 18–85 years (median 56) over a period of 10 years. Sixty‐five patients had extramedullary leukaemia, 13 had clinical signs of leucostasis, and 19 had disseminated intravascular coagulation. Four patients died before receiving any treatment, 12 received supportive care only and seven received low dose AraC, but only one of them responded. Seventy‐six patients received intensive chemotherapy, 72 of them with an anthracycline‐AraC based regimen, with or without an epipodophyllotoxin.