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Beware the lymphopenia: A case of severe combined immunodeficiency

We present a case of a 2‐month‐old boy with partially treated meningitis and suspected Pneumocystis carinii pneumonia. A full blood count revealed profound lymphopenia. The child was diagnosed with adenosine deaminase deficiency, a rare cause of severe combined immunodeficiency (SCID). SCID is an immunological emergency and must be considered in any lymphopaenic infant with opportunistic infection. We discuss adenosine deaminase‐deficient SCID, which can involve multiple systems and in which other treatment options apart from bone marrow transplant are available.