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Prolactin in obese children: a bridge between inflammation and metabolic‐endocrine dysfunction

Adipocytes, regulated by insulin, represent the major peripheral source of prolactin (PRL), which play a pivotal role in energy balance, acting on adipogenesis and lipolysis. The aim of this study was to investigate whether PRL was associated with obesity‐related inflammatory status and metabolic parameters. The diagnostic and prognostic role of PRL for metabolic syndrome (MS) was assessed. The effects of short‐term lifestyle therapy on PRL levels were evaluated.