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Purification of active substances of Aloe arborescens miller and their biological and pharmacological activity

We purified Aloctin A from Aloe arborescens Miller and defined its chemical, biological and pharmacological activities. Aloctin A consists of two discrete bands, α and β with a combined S–S bond. Its molecular weight for α is 7500 and the molecular weight for β is 10 500. Aloctin A has many biological and pharmacological activities as follows: 1. Haemagglutinating activity; 2. Cytoagglutinating activity; 3. Mitogenic activity of lymphocytes; 4. Precipitate‐forming reactivity with α2‐macroglobulin; 5. Complement C3 activating activity; 6. Inhibition of heat‐induced haemolysis of rat erythrocytes; 7. Antitumour effect; 8. Antiinflammatory effect; 9. Inhibition of gastric secretion and gastric lesions.