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Comparison of nonlinear and linear imaging techniques at high frequency

High frequency second harmonic imaging was compared with fundamental imaging in terms of lateral resolution, depth of field and image quality. In order to assess the fundamental beam at 20 MHz, the harmonic beam at 40 MHz, and the fundamental beam at 40 MHz of a 40 MHz broadband transducer, transmission measurements were performed using a hydrophone. The beam profile obtained using each of these techniques was estimated in a tissue-mimicking phantom. Image quality was evaluated in phantom and mouse tissue in vitro.