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Scanning electron microscopic study of the human fallopian tube. 3. The effect of midpregnancy and of various steroids.


 The scanning electron microscope was used to examine fallopian tubes removed from 18 women including 3 on the low dose progestin contraceptive .5 mg megestrol acetate, 3 on different combined oral contraceptives, 3 fertile and 3 postmenopausal women on .05 mg ethinyl estradiol, 3 women 18-20 weeks pregnant, and 3 transsexuals injected monthly with 250 mg testosterone enanthate. The microscope revealed few differences in cell distribution or structure. More ciliated cells, usually located on edges of plicae, and fewer secretory cells were found in the ampulla and infundibulum than the isthmus and intramural portions of the endosalpinx. Subjects taking progestogen, or in midpregnancy had a normal distribution of ciliated cells, but the cilia appeared drooping and granulated. Both fertile and postmenopausal subjects taking estrogen had tall, vigouous cilia. Only testosterone decreased the number of ciliated cells in the distal tube significantly.
