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[Characteristics of microbiocenosis of gingival pocket in patients with chronic generalized periodontitis].

As a result of examination of 56 patients with chronic generalized periodontitis (CGP) of a moderate severity and a severe form of the disease, microflora from gingival pocket in patients which severe form of CGP was established to have higher specific weight in index of dissemination of strains such as Staphylococcus aureus, Streptococcus pyogencs, Enterococcus, Corynebacterium spp., anaerobic bacteria. Strains from patients with a severe form of CGP were characterized by a higher level of expression of the factors of pathogenicity and persistence. Associations of streptococci and staphylococci which the representatives of anaerobic flora such as Bacteroides, Fusobacterium, Prevotella, Clostridium, Peptostreptococcus were more often revealed in patients with a severe form of CGP. Fact of microbial translocation from the gingival pocket was established: from the blood of the patients with CGP of a severe form, strains-translocants were cultivated by 4 times more frequently than from the patients with CGP of a moderate severity.