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1072 ASSOCIATION OF SEX AND AGE WITH AN INDIVIDUAL'S RISK OF HIGH BLOOD PRESSURE, IN A LARGE AUSTRALIAN COHORT

Background: Differences in risk of having high blood pressure (HBP) between males and females have not been reported across the age spectrum within a large Australian cohort. The aim of this study was to determine the association between sex and high blood pressure in Australians aged 45 years and over. Design and methods: Data for this study were derived from self reported data obtained from the 45 and Up Study baseline questionnaire. HBP data was sourced from participant's response to the question “Has a doctor ever told you that you have: high blood pressure.” All analyses were adjusted for demographic and lifestyle characteristics and individuals were grouped into 10 year age bins. Results: A total of 237,877 participants were included in the analysis, of which 28% reported having HBP. There was an association between sex and HBP, with males having a higher risk of HBP in the 45–54 (RR 1.33, 99%CI 1.26–1.40, P < 0.001) and the 55-64 age group (RR 1.18, 99%CI 1.13–1.22, P < 0.001) and a lower risk of having HBP in the 75-84 (RR 0.88, 99%CI 0.84–0.92, P < 0.001) and 85+ (RR 0.80, 99%CI 0.71–0.88, P < 0.001) age groups, compared to females. There was no association between sex and HBP in the 65-74 age group (RR 1.00, 99%CI 0.97–1.04, P = 0.91). Conclusions: An individual's sex is associated with risk of having HBP, and the risk varies according to the age of the individual. Sex and age should be considered when determining an individual's risk of having HBP.