{'fraction_non_alphanumeric': 0.029465930018416207, 'fraction_numerical': 0.003683241252302026, 'mean_word_length': 5.906779661016949, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Hyperandrogenism and Excess Weight Gain

Polycystic ovary syndrome (PCOS), a form of functional ovarian hyperandrogenism, is the most frequent cause of androgen excess in adolescents and women of child-bearing age, with a prevalence estimated between 5 and 10 per cent". Variance in prevalence among populations may reflect the effect of ethnic origin, race, and other environmental factors on the phenotype . The presenting signs and symptoms of PCOS are heterogeneous and vary over time; however, the endocrine-metabolic hallmark is hyperinsulinemic hyperandrogenism, even in the absence of obesity. Dyslipidemia, disadipocytokinemia (specifically, increased interleukin-6 [IL-6] levels and decreased adiponectin concentrations), increased C-reactive protein (CRP) levels, relative leukocytosis, excess central fat and lean mass deficit are frequent associated abnormalities". The insulin resistance of PCOS, together with the atherogenic lipid profile, the dysadipocytokinemia, the increased CRP levels and abdominal obesity, appears to impart an increased risk for glucose intolerance, type 2 diabetes mellitus, and cardiovascular disease'. Both PCOS and the metabolic syndrome characterized by the association of obesity, dyslipidemia, and hypertension share insulin resistance as a central pathogenetic feature; PCOS has thus recently been proposed as a sex-specific form of the metabolic syndrome, and the term 'syndrome XX' has been suggested to underscore this association. Recent advances in the pathogenesis of PCOS suggest that hyperinsulinemic insulin resistance is a key factor accounting for the development of the