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The Diverse and Heterogeneous Clinical Features of Juvenile Psoriatic Arthritis

Abstract Juvenile Psoriatic Arthritis (JPsA) is a chronic inflammatory disorder that accounts for 3-10% of all juvenile arthritis. The main objective is to identify the clinical features of psoriatic arthritis in children. This study was open-label, single-center, prospective, observational (1989-2020) cohort clinical study included 85 patients (3-17.0 y/o) who met Vancouver and I/E criteria. The features of skin and articular syndromes in children with JPsA were revealed. In most patients with PSA, the disease began at the age of 6.6 years. In childhood, arthritis is usually preceded by psoriasis. The most common clinical form of psoriasis is plaque psoriasis. At the onset of the disease, symmetric polyarthritis predominates. During the disease, transformation of the joint syndrome with a predominance of rheumatoid arthritis is noted. All observed patients showed pronounced osteoporosis, which is not characteristic of JPsA.