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Acute disseminated fatal toxoplasmosis in a squirrel monkey.

Acute disseminated toxoplasmosis was diagnosed in an adult male squirrel monkey (Saimiri sciureus). The disease was characterized by severe pulmonary edema, diffuse interstitial pneumonia, and multifocal areas of necrosis along with Toxoplasma organisms in the lungs, liver, spleen, lymph nodes, adrenal glands, and heart. Small numbers of organisms were found in bone marrow, renal glomeruli, and renal tubular epithelial and interstitial cells. Small numbers of organisms also were associated with foci of hemorrhage in the brain. The source of the infection was not determined.