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Most of diaplacentally transferred allergen is retained in the placenta

Background Transplacental transfer of nutritive and inhalant allergens has been described being potentially responsible for a series of events leading to antigen‐specific immune responses in the fetus. As such, cord blood T cell responses appear ubiquitously. However, studies failed to reveal a consistent dose–response relationship between antenatal allergen exposure and allergen‐specific cellular reactivity in cord blood.