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ABCA7 gene as a potential therapeutic target in the management of Alzheimer's disease

ABCA7 is a gene that belong to the family of ATP‐binding cassette (ABC) transporter gene superfamily. Based on their structure and sequence homology, ABC transporters are divided into seven sub families. Asides from its function in lipid transport, high levels of ABCA7 is expressed in the hippocampus and has been identified with Alzheimer’s disease (AD) risk. Over time, research has been done to identify therapeutic targets in the management of Alzheimer’s disease.