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Collagenous Colitis Associated with Rabeprazole in a Peritoneal Dialysis Patient

endoscopic appearance of CMV colitis is variable; round-shaped ulcers are the most distinctive features, but not specific. The definitive diagnosis requires histopathologic evidence of viral cytopathic effects, and the sensitivity is augmented by immunohistochemistry or polymerase chain reaction (PCR) for CMV deoxyribonucleic acid (DNA) (3,4). The colitis in our patient was not self-limited, but subsequently improved with ganciclovir therapy. A meta-analysis of immunocompetent patients with CMV colitis reported a lower rate of spontaneous remission (18.8%) and a mortality of 56% in individuals with renal failure, diabetes mellitus, pregnancy, or untreated cancer (1). Antiviral therapy is probably beneficial to patients with comorbidities or persistent symptoms. In conclusion, the presence of B. fragilis in PD peritonitis is more commonly associated with intra-abdominal pathologic states, and CMV colitis should be considered even in the absence of immunosuppression.