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Long term follow-up of surgical adrenalectomy for breast cancer.

A long term follow-up of 300 patients treated by bilateral adrenalectomy for advanced breast cancer is presented. The notable features are the lengthy remissions and survival times which occurred in some patients. This is further evidence of at least two important biological subsets within the general population of breast cancers. Of the responders, 11% were still in remission at four years and 10% were alive at 10 years. Responders also enjoyed a good quality of life. These results are of considerable importance in assessing the relative merits of newer methods of treatment.