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Stability of Neutrophil‐Releasing Activity of Plasma Obtained from Leukapheresed Rats and Stored at 4 C

When granulocyte‐donor rats were treated prior to pheresis with plasma obtained from previously leukapheresed rats (PPP), granulocytosis and a significant increase in granulocyte yield were observed. Previous studies have demonstrated that such plasma stored at –150 C for up to two weeks preserved the neutrophil‐releasing activity. This study demonstrates that neutrophil‐releasing activity was satisfactorily preserved when plasma from previously leukapheresed rats was stored at 4 C for three weeks.