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Diabetes insipidus and complicated pregnancy.

DIABETES insipidus is a rare disease. Its coexistence with pregnancy has been reported rarely. In only a few previous cases has preeclampsia been added to the clinical picture. Report of a Case A 24-year-old woman, gravida 1, para 0, was admitted at 38 weeks' gestation because of impending toxemia. Her last menstrual period had begun on Jan 10, 1977, and her expected delivery date was Oct 17, 1977. She was admitted to the hospital on Oct 3, 1977. She had a history of idiopathic diabetes insipidus since age 12. She had been treated with vasopressin (Pitressin) tannate in oil until the age of 21 when the drug therapy was switched to desmopressin acetate given by nasal spray. Her condition was well controlled with 0.25 mL/day in divided doses. At initial prenatal examination on March 11, 1977, she had appeared to be normal, and uterine size agreed with her period of