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Host Cell Deoxyribonucleic Acid Polymerase I and the Support of T4 Bacteriophage Growth

Ultraviolet irradiation of Escherichia coli polA− cells reduces their capacity to support the growth of T4 phage. There is no additional loss of capacity observed in pol tsA−recA− double mutants at the nonpermissive temperature. The reversion frequency of a T4 rII mutant after ultraviolet irradiation is not changed by the absence of host deoxyribonucleic acid polymerase I.