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326 Pure tubular carcinoma of the breast: a rare entity

Introduction Pure tubular breast carcinoma (PTC) is a rare and well-differentiated tumor with good outcomes and a low local recurrence rate. Our study aims to determine the clinical, radiological, and appropriate management and the prognosis of this rare entity. Materials and Methods A review of Salah Azaiez institute registry from 2004–2019 was performed including seven cases of PTC of the breast. Results Seven patients were included in this study. The average age was 54 years old (from 36 to 70 years) and all patients were female. Physical exam revealed a breast lump in 6 patients. Six cancers were clinically detected on physical examination. In one patient the diagnosis was made by mammography. The radiologic findings were variable (BIRADS 3 in 6 cases and BIRADS 5 in one case). In our study, we found that. 5 patients presented with T1 and N0 according to the TNM classification. The radiological assessment did not show any metastasis. The conservative surgery was more frequently performed (5 cases). All patients had hormone-receptor positivity and HER-2 negativity. Six patients were luminal A, and one patient was luminal B. In one case we found axillary lymph node metastasis. The adjuvant radiotherapy was indicated in all cases of breast conservation and only in one case of radical surgery. Only one patient received chemotherapy. Conclusion The PTC shows an excellent prognosis with a low SBR grade and a molecular profile luminal A and a low incidence of recurrence.