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Risk-benefit profile of inhaled corticosteroids in COPD is still unclear

Park and colleagues’ review acknowledges the harms associated with using inhaled corticosteroids for chronic obstructive pulmonary disease (COPD).1 To help clinicians make informed decisions, we wish to clarify the absolute benefits and harms.

Estimates of benefit were less optimistic in an up-to-date and comprehensive Cochrane review,2 partly because of Park and colleagues’ unconventional derivation of the number needed …