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Rapid bolus injection of radioisotopes.

Reliable introduction of a single bolus of tracer following antecubital injection is mandatory for the application of critical diagnostic techniques. The assumption of such a bolus entry has been found to be invalidated by many common injection methods. A scintillation camera-computer combination was used to record time-activity histograms of a radionuclide bolus as it passed through the axilla and into the heart following antecubital injection. Such factors as injection site and position of the arm and shoulder were found to affect bolus characteristics. Examples of rapid bolus introduction into the right heart are presented.