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Neonatal Diabetes Mellitus with Severe Hypertriglyceridemia

Neonatal diabetes mellitus is very uncommon. It is often transient, lasting for weeks to months; however its course is highly variable. Poor diabetic control in children with insulin dependent diabetes mellitus (IDDM) is associated with hypertriglyceridemia and hypercholesterolemia. Previous reports in children show hyperlipidemia in association with diabetic ketoacidosis; however, transient neonatal diabetes mellitus (TNDM) is known to occur in the absence of ketonuria. To date no case of neonatal diabetes mellitus with secondary hyperlipidemia and lipemia retinalis without a co-existing genetic form of lipid disorder has been described.