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Set-up of a biological monitoring module realized in LTCC technology

Low temperature co-fired ceramic (LTCC) technology was originally developed for the realization of multilayer circuits of high reliability. It was recognized that LTCC technology is a valuable development in thick film technology, which launches new application areas as it becomes evident that complex three-dimensional structures can easily be realized. When considered for biological applications ceramic tape material must be proved with regard to its biocompatibility. A selection of appropriate commercially available ceramic tapes has been characterized in respect to the influence on proliferation, viability and adherence of cells. Aspects of realization of a complex biological monitoring module comprising a three-dimensional network of channels and cavities will be demonstrated.