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Helicobacter pylori Induces Vascular Endothelial Growth Factor Production in Gastric Epithelial Cells Through Hypoxia‐Inducible Factor‐1α‐Dependent Pathway

Although Helicobacter pylori have been known to induce vascular endothelial growth factor (VEGF) production in gastric epithelial cells, the precise mechanism for cellular signaling is incompletely understood. In this study, we investigated the role of bacterial virulence factor and host cellular signaling in VEGF production of H. pylori‐infected gastric epithelial cells.