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Emerging Infections 3

Scheld WM, Craig WA, Hughes JM, eds. 258 pages. Washington, DC: ASM Pr; 1999. $69.95. ISBN 155581168X. Order phone 800-546-2416. Field of medicine: Infectious diseases, public health, microbiology, and epidemiology. Format: Softcover book. Audience: Physicians in general medicine and infectious disease, public health officials, pathologists, and microbiologists. Purpose: To review emerging infectious diseases that pose major clinical and public health challenges throughout the world and to emphasize the critical importance of detecting, responding to, and controlling outbreaks of these infections. Content: Based on Interscience Conference on Antimicrobial Agents and Chemotherapy Annual Symposia on Emerging Infections, the book features in-depth discussions of selected infections from the basic science and clinical viewpoints. Included are reviews of hepatitis E; new rickettsioses; unusual salmonella and streptococcal infections; and parasitic infections, such as leishmaniasis and Chagas disease. Pathogenic microalgae and the role of emerging infections in animals as precursors to human illness are covered. Of interest are chapters on infections in xenotransplantation and the role of the pathologist and medical examiner in recognizing unusual infections. The book emphasizes the responsibility to public health in identifying and treating emerging infections and the need to recognize and respond to domestic terrorism involving infectious agents. Highlights: Each chapter presents interesting historical background and clinical descriptions of diseases from a global perspective. The book is well organized; discussions progress from familiar diseases, such as hepatitis, to rarer infectious agents and conditions, such as pathogenic algae and diseases transmitted by transplantation of animal tissues into humans. Methods of molecular diagnosis have improved our understanding of these unusual diseases, many of which have emerged as a result of human manipulation of fragile ecosystems. The authors emphasize that control of these infections represents a continuing challenge requiring a multidisciplinary global approach. Limitations: The book is by no means comprehensive, since it is one in a ongoing series of annual publications dedicated to the topic. Related reading: Emerging Infections 1 (ASM Pr, 1997) and Emerging Infections 2 (ASM Pr, 1998) review other important emerging pathogens. Mandell and colleagues' Principles and Practice of Infectious Diseases (Churchill Livingstone, 2000) places unusual agents in context with related pathogens in a well-referenced and readable format. Reviewer: Nicholas J. Lekas, MD, Oakwood Hospital and Medical Center, Dearborn, Michigan.