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Antithrombotic drugs in peripheral arterial diseases

Antiplatelet therapy is indicated in all patients with carotid artery stenosis irrespective of clinical symptoms and revascularization. Dual antiplatelet therapy should be given for at least one month after carotid artery stenting. Single antiplatelet therapy is indicated only if LEAD patients are symptomatic or have undergone revascularization. Clopidogrel is the preferred antiplatelet drug in LEAD patients. Chronic anticoagulation therapy is given only if there is a concomitant indication and may be combined with single antiplatelet therapy when there is a recent revascularization procedure.