{'fraction_non_alphanumeric': 0.02973977695167286, 'fraction_numerical': 0.013940520446096654, 'mean_word_length': 5.016759776536313, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Effect of Calcitonin Gene‐Related Peptide on Passive Avoidance Behavior in Rats

Calcitonin gene-related peptide (CGRP) is widely distributed in the peripheral and central nervous systems.1-6 Despite the great deal of information available concerning its action in the periphery,’-IS very little is known about the direct action of CGRP in the central nervous system. CGRP may participate as a mediator/modulator in chronic pain, and it may play a role in antinociception at the level of cerebral structures rather than in the spinal cord.16 We investigated the action of CGRP, administered into the lateral brain ventricle, on passive avoidance behavior (one trial learning) in rats. An attempt was made to clarify the possible involvement of neurotransmitters in the behavioral action of CGRP. CGRP (Bachem, California) was administered icv in doses of 200 ng, 300 ng, 500 ng, or 1 pg. It was given before the learning trial (measuring the action of the peptide on learning), immediately after an unavoidable foot shock (action on consolidation of memory), 6 hours after the