{'fraction_non_alphanumeric': 0.013640238704177323, 'fraction_numerical': 0.0, 'mean_word_length': 5.311827956989247, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
PROGRESSIVE DEMENTIA CAUSED BY AN UNUSUAL TYPE OF GENERALIZED SMALL VESSEL THROMBOSIS

The clinical and pathologic findings are reported in three elderly patients with an unusual type of generalized thrombosis of small arteries and veins throughout the body. The main ischemic lesions were found in the brain. The symptoms progressed over several years. The main symptom in all cases was a progressive dementia. In addition, there were signs of progressive cortical blindness, ischemic disease of the peripheral nerves with peripheral pareses, and peripheral vascular disease of the legs. There were no signs of primary vascular disease which could explain the precipitation of the thrombi. Detailed hematologic examinations were performed in one case. The platelet counts in this case were normal, but there was a marked decrease in the platelet survival time. The increased platelet consumption probably was caused by the continous thrombus formation. The coagulation studies did not show increased blood coagulability, and treatment with heparin and rheomacrodex did not influence the platelet survival time. The mechanisms of the thrombus formation thus remain obscure.