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Humoral Immune Response to Avian Influenza Vaccination Over a Six-Month Period In Different Species of Captive Wild Birds

Study Results In December 2005 the four major Swiss zoos carried out the vaccination of selected zoo birds with the adjuvant inactivated vaccine H5N2 Nobilis influenza. Within the non-Galliformes, significant differences in geometric mean titres were found among different species representatives. In general, the flamingos (Phoenicopteriformes) showed a strong response to vaccination reaching a geometric mean titre of 659 at week 10, while the Sphenisciformes did not show high antibody titres even after booster vaccination, reaching a maximum geometric mean titre of only 65. Based on the antibody titre profiles of all investigated species, researchers recommend at least annual revaccination in the species that were investigated.