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Prostate cancer with clear cell features and an unusual nested-like pattern of growth: a case report.

BACKGROUND
Clear cell carcinoma of the prostate is rare, with the majority of reports consisting of a single case study.


CASE
We report a case of prostate cancer with unusual cytoplasmic clearing and a nested-like pattern of growth observed in an 80-year-old patient with lower urinary tract obstruction. Emphasis is placed upon differential diagnosis and the distinction from other clear cell carcinomas arising in the urinary tract, both at a histological and immunohistochemical level.


CONCLUSION
Androgen receptor immunohistochemistry seems to be a useful tool to distinguish prostate origin from secondary clear cell tumors.