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[Effect of intravenous administration of nitroglycerin on the lesion size in acute myocardial infarct].

A controlled study conducted in 60 patients (treated group 33 patients, control group 27 patients) showed that intravenous infusion of nitroglycerin results in 4 hours in a significantly positive dynamics of the parameters of precardial cartogram in 35 leads. Study of serial activity of CPK and MB fraction of CPK showed that a significant difference in the size of the affection is revealed only by the results of CPK examination. It was also established that a diminution in the size of the affection is possible both in increased end diastolic pressure in the pulmonary artery and in normal initial value, which does not allow the mechanism of the protective nitroglycerin effect to be explained only by the hemodynamic action of vasodilation.