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All you need to read in the other general journals

Glucosamine is a popular treatment for osteoarthritis with a patchy evidence base. Researchers from Norway are now fairly sure glucosamine doesn’t work for people with low back pain, after their trial found that the drug had no effect on pain, disability, or quality of life. Adults with longstanding low back pain and evidence of osteoarthritis on magnetic resonance imaging took glucosamine or a placebo for six months. Both groups felt better at the end of treatment and six months later, with matching scores measuring pain related disability and quality of life. A similar proportion of both groups used other treatments such as sessions with a chiropractor, physiotherapy, or analgesic drugs. The trial was powerful enough to be convincing, say the authors. Glucosamine didn’t work for this population of Norwegian adults, and doctors probably shouldn’t prescribe it. Their 250 participants had a mean age close to 50 and a mean body mass index of 25.4. Three quarters had had low back pain for at least four years, although most were still in work. Short telomeres suggest higher cancer risk