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Construction and validation of an educational video for human papillomavirus vaccination

Rev Bras Enferm. 2020;73(4): e20180900 http://dx.doi.org/10.1590/0034-7167-2018-0900 7 of ABSTRACT Objectives: to validate an educational video aimed at the adhesion of human papillomavirus vaccination. Methods: a methodological study, where the knowledge about the theme and the technology to be constructed in six focal groups was identified; a theoretical framework was set up and the existing videos were uploaded. After that, pre-production, production and post-production were followed. In validation of content, 22 specialists participated, and in appearance, ten adolescents, ten mothers, ten teachers and ten audiovisual professionals. Absolute frequency, Binomial Test, and Content Validity Index were used. Results: agreement was satisfactory in most items. Regarding relevance, 20 items had indices above 0.80 among judges. Assessment was positive among girls and mothers. Only three items had indices less than 0.80 among teachers and video professionals. Conclusions: the educational video was validated, conferring credibility to contribute to educational actions and improve vaccination indexes. Descriptors: Construction; Validation Studies; Video-Audio Media; Vaccination; Papillomaviridae.


INTRODUCTION
The quadrivalent human papillomavirus (HPV) vaccine was introduced in the Brazilian Unified Health System (SUS -Sistema Único de Saúde) in 2014 as a strategy for the prevention of cervical cancer, which has a high incidence and mortality, including in developing countries. The production of this vaccine is associated with virus infection, with subtypes 16 and 18 accounting for about 70% of the cases of neoplasm. This and other evidence on immunobiology are poorly understood and interfere with its acceptability (1)(2) , although approval for use in women occurred in 2006 and in humans in 2009, attesting to safety in administration (3) .
In Brazil, the Ministry of Health (MoH) currently determines that the target population for vaccination is girls aged 9 to 14 and boys aged 11 to 14 years. By 2020, the age range of immunization in the male population is expected to increase from nine to 14 years (4) . Since vaccine became available in the public health network, concerns arose in families about early sexual life of the young and fear of adverse events after immunization. The information disclosed in the media and social networks are another aggravating factor that can impair adherence and, consequently, failure to comply with the vaccination schedule, leading to a decrease in immunization rates (1) .
In 2014, HPV vaccination rates in Brazil were approximately 99.8% and 55.7% for the first and second doses, respectively, when the vaccine was offered to girls aged 11 to 13 years (5) . By 2017, vaccine coverage in girls was 82.6% and 52.8%, respectively for the first and second doses, and 43.8% for the first dose in boys (1) . These results demonstrate a significant reduction in vaccine administration, weakening the fight against cancer.
Encouraging vaccination, through educational actions, is necessary in this setting, making the knowledge about the subject accessible and sensitizing different publics, especially in schools, that needs practices that promote quality of life. To this end, it is recommended to use modern technologies such as videos (1) . It stands out for the ease of access and ability to streamline didactic-pedagogic activities, constituting a resource that enhances learning, such as educational video. However, many videos available do not present persuasive communication, a strategy useful for generating healthy behaviors (6) .
The development of an educational tool with the participation of the target public of vaccination, parents and health and education professionals gives the material credibility to contribute to health education actions and, thus, improve the vaccination indexes, which are currently below expected. This development is based on official information about immunobiological and reliable references submitted to the validation by specialists and other actors involved with immunization and video production, that can boost thinking for the change of attitudes and behavior.

OBJECTIVES
To validate an educational video aimed at the adhesion of human papillomavirus vaccination.

Ethical aspects
The study was approved by the Research Ethics Committee of the Health Sciences Center of the Universidade Federal de Pernambuco, through submission to the Brazil Platform (Plataforma Brasil). It followed the recommendations of Resolution 466/12 of the Brazilian National Health Board (Conselho Nacional de Saúde).

Design, place of study and period
The study is of the methodological type, which develops, validates and assesses tools and research methods (7) . As no specific tools were found to guide this methodology, it was decided to follow a sequence of procedures based on the literature, namely: construction of the initial version of the educational video (8) , validation of content (9) and validation of appearance (9) .
In the first stage, diagnosis of knowledge and attitudes about HPV and vaccination was made, and the educational tool was chosen through six focus groups from June to July 2015. The operationalization of these groups occurred in elementary schools, municipal and state, and health units located in Health District IV of the city of Recife, Pernambuco State, defined by lottery. In the group of higher-level health professionals, the activity was developed during the District's administrative meeting.
Validation of content occurred in November and December 2015, while the validation of appearance, carried out in the municipal public schools and state elementary schools of the same District, occurred in December 2015.

Population or sample, inclusion and exclusion criteria
Focus groups were constituted of six students, ten adolescents, nine mothers, ten teachers, seven Community Health Agents (CHA) and 13 higher level health professionals (10) selected by intentional sampling (7) .
As inclusion criteria for participation in the groups, students should be in the age range of vaccination, which corresponds to the series from the fourth to the eighth year. Those who were excluded from school activities due to illness or suspension were excluded. The invitation to participate in the study was made to the parents, but only the mothers were available to attend the meeting. It was necessary to have daughters with the described profile, being excluded those that had some cognitive limitation. Teachers should teach in the mentioned series and health professionals work in local health units.
In the validation of content stage, 22 professionals (11) participated in the areas of women's and/or adolescent's health, public health, collective health and health education, teaching or assistance, with at least five years of practice. The selection followed the inclusion criteria based on the experiment classification system adapted from the Fehring model (12) , considering a specialist with at least five points. The active search of the same occurred in the Lattes Platform (Plataforma Lattes), being the sampling of the intentional type (7) . of

Construction and validation of an educational video for human papillomavirus vaccination
Interaminense INCS, Oliveira SC, Linhares FMP, Guedes TG, Ramos VP, Pontes CM.
Validation of appearance was performed with ten adolescents, ten mothers and ten teachers (13) selected by the same criteria used in the focus groups. Only mothers were available. Ten professionals from the video area (13) , with experience in production and publication participated, and were selected by chain sampling (7) .

Study protocol
In the development of the focus groups, a script was developed with five guiding questions, adapted according to the participating public, on HPV, immunization and educational materials, using the problematizing methodology. They had an average duration of 37 minutes. From the transcription of the audios and exhaustive reading of the texts, the knowledge and attitudes about the subject and the video as the chosen educational technology were identified.
Subsequently, a video survey was conducted and a theoretical framework was made on HPV and vaccination. There were also verified productions with the theme in the collections of the Oswaldo Cruz Foundation (Fundação Oswaldo Cruz), MoH, State Health Offices of Brazil and Federal District, to make a video different from those previously published, being located 22 audiovisual materials. All of these steps contributed to the video's script.
The educational video production process was organized in three stages: pre-production, production and post-production (8) . In pre-production, the idea was defined, followed by script writing (14) , with suggestions from teachers of Social Communication and Pedagogy. Characters and settings were created in CorelDRAW ® , from where the storyboard was extracted (8) .
At production stage, the educational video was constructed in the second dimension animation format (2D). Body movement and facial expressions of characters were performed with the GoAnimate ® program. The audio of the speech was recorded in a reserved place with adequate acoustics. In post-production, the edition used Final Cut Pro ® . The initial version of the video was converted into MP4 format.
For validation of content, an electronic form was created in Google Forms ® , which was sent by e-mail. In it, the tool for validation of content was included, which assessed agreement and degree of relevance in 25 items. This tool, adapted from two validation studies of educational materials (6,13) , followed a specific assessment script (14) .
In the validation of appearance, it was made the invitation and delivery/sending of the documents to participants, the educational video was watched and the instrument of validation of appearance, adapted from two studies (6,13) , was filled out.

Analysis of results and statistics
The data were analyzed in the IBM ® SPSS ® Statistics software, version 20.0, describing the absolute frequencies. For validation of content, the Binomial Test was applied to the items of the tool, verifying the agreement ratio among judges, with an agreement index equal to or greater than 85% (P > 0.85) and a 5% level of significance (α) (13) . For relevance degree analysis of the items, Content Validity Index (CVI) was calculated by three mathematical equations, considering a content index validity > 0.80 (7) . In the analysis of the understanding of the educational material by the other participants, the CVI was calculated for each item of the tool of validation of appearance.

RESULTS
In all focus groups, doubts and different levels of knowledge about HPV and vaccination were evidenced. The girls were unaware of the virus itself, linking it to cervical cancer and the vaccine, which also fights other cancers.
It is a ... breast cancer, skin cancer, cervical cancer vaccine (adolescents focus group).
About vaccines, there was the conception in all groups that it prevents cancer, but it was not seen among the mothers and their mothers that the protection is specific for cervical cancer, since it has been generalized with other diseases.
The girl grows protected. Prevents against cancer of the cervix and other diseases more, other than that there also. (parents focus group) Resistance of girls and parents to HPV immunization has been reported by practitioners. It is noticed how the population is afraid of vaccination due to lack of knowledge about the subject.

Some people do not want to vaccinate in my area because they say it's bad. You will only get vaccinated after other girls get vaccinated and see that you did not give a problem. (CHA focus group)
To encourage vaccination, some actions were mentioned, such as publicity about campaigns, fairs, waiting rooms, shelters, home visits, schools and other social facilities, social networks, television and groups of adolescents. The trip to the health service with the youngest to administer the vaccine was also mentioned.
Educational materials, posters, pamphlets, comics, slides, games and puppet theater were suggested to talk about the vaccine, but the video was highlighted by the possibility of drawing more attention, as well as ease of viewing and sharing, based on successful previous experiences.
As in the unit we have the television in the waiting room and the DVD, video with us works. (higher education health professionals focus group) Regarding the content that the material should address, questions and answers on the subject were recommended; stories/narratives involving vaccination; explanations about the female reproductive system, the virus, cervical cancer and the vaccine; vaccination; presence of an expert in the subject to provide explanations; myths and truths about immunization and consequences of non-vaccination.
The theoretical framework was composed of topics related to HPV, cervical cancer and vaccination against the virus. The audiovisual productions found in the researched collections were motivational and informative videos, with campaign messages and technical information about the vaccine, none of them offering the knowledge from real situations and constructed from the diagnosis made with the population.

Construction and validation of an educational video for human papillomavirus vaccination
Interaminense INCS, Oliveira SC, Linhares FMP, Guedes TG, Ramos VP, Pontes CM.
The script for the first version of the educational video resulted in a narrative consisting of seven characters and four scenes occurring at school, home and health unit. Conflicts about HPV vaccination in the daily routine of a traditional family and the decision-making of the parents for the immunization of their daughter based on knowledge acquired with an education professional and another about health were emphasized (Figure 1).
The storyboard was developed based on the first script, and presented six images, giving an idea of the physical characterization of characters, settings, colors, actions and emotions present in the video. Production and editing originated the first version called "It's time to protect yourself with the HPV vaccine", which lasts approximately 11 minutes.
In the validation of content, 19 judges belonged to higher education institutions in the Northeast and Southeast regions: 11 were specialists in women's health, seven specialists in public health or collective health and 17 had a doctorate. Besides these, three were from Northeastern care services, all with specialization in women's health and master's degree.
Agreement among judges for the assessed items was satisfactory in most of them, except for item 16, in which there was agreement/disagreement tie (11/11), and in item 17, in which 13 judges disagreed. P value was >0.05 in 22 items, indicating the proportion of judges who agreed with the adequacy and relevance of the educational video ( Table 1).
Relevance of the items expressed by the I-CVI (Item-Level Content Validity Index) separately, with the value of the S-CVI (Scale-Level Content Validity Index) can be visualized in Table 1. I-CVI was >0.80 in most items assessed, except for items 5, 7, 13, 16 and 17. Relevance ratio (S-CVI/AVE, Scale-Level Content Validity Index, Average Calculation Method) was equal to or above 0.80 for 17 judges.
The emitted suggestions led to modifications in items that had I-CVI below 0.80. The opening became more dynamic and attractive, with questioning about the vaccine, inviting music, appropriate lyrics and beginning of the narrative in the classroom. To increase interest in the video, more action was  taken to events, movements and dialogues, so as not to make it monotonous. About characters, some audios were re-recorded with more expressiveness and motivation. To give more emotion,

Construction and validation of an educational video for human papillomavirus vaccination
Interaminense INCS, Oliveira SC, Linhares FMP, Guedes TG, Ramos VP, Pontes CM.
the speech became engaging and spontaneous, becoming more real. On the humor, the dialogs acquired a more adolescent performance, having interaction among students.
In the validation of appearance, the positive assessment of 100% of adolescents (A) and mothers (M) on the aspects related to the educational video revealed: The opening of the video is interesting. I did not know, I learned more and more. Most items obtained I-CVI equal to or above 0.80. Among teachers, items 4 and 5, regarding the length of the video and the ability of the scenes to convey the content, presented I-CVI of 0.70 each. Among video professionals, only item 4 had the I-CVI of 0.70. S-CVI/AVE was greater than 0.80 for most participants. S-CVI was above 0.80 for all groups.
To improve the video, the narrative time was shortened with the speech of characters processing at a faster pace, reducing pauses in movements, passage of scene and opening. To convey the message better, voices became even more spontaneous. In the classroom, blackboard showed information about vaccine and background colors were changed by the conventional setting, so as not to divert the viewer's attention.
The implementation of some suggestions emitted in the validation of the educational video resulted in a final version of the more dynamic material, with less duration and more details related to its content and the visual question.

DISCUSSION
The poorly detailed and confused knowledge about HPV and the vaccine against the virus, evidenced in the focus groups for the construction of educational technology, may be related to the immunobiological being a new method of cancer prevention offered by the MoH in Brazil, from 2014. Previously, it was little publicized, although production began in 2006. Since the implantation, doubts have arisen about its effectiveness and safety (15) . Thus, the video constructed sought to address issues that meet the demands of the groups, translating into a dynamic resource for dissemination of knowledge.
The diagnosis of HPV and vaccination in focus groups allowed identifying what is known about the topic, the gaps, information needs and video as educational technology. This has given a differential to the material, which will lead to the knowledge about the vaccine that is based on the reality of the population and which can provoke reflections for behavior changes, favoring vaccination. In a similar way, a survey was carried out with chaperones about the knowledge in the subject in the elaboration phase of an educational manual (16) . However, other ways can be followed in the construction of an educational video, based on research on the subject (17) .
The video was the technology chosen, in this study, to be attractive, easily accessible and for contributing to the learning in educational actions in the community. Their employability could promote satisfactory outcomes by increasing vaccine indices and preserving women's health. It is expected that its effect will be similar to that provoked by a video on the knowledge about the postoperative care of children with cleft lip and palate, with favorable results for the intervention group, proving the efficacy of this material in experimental studies (18) .
According to the World Health Organization, two doses of the HPV vaccine are sufficient to protect against cervical cancer (19) . Thus, the educational video elaborated sought to meet this recommendation and respond to the concerns generated in focus groups. Conflicts related to resistance to immunization were also addressed, aiming to demystify conceptions that prevent the protection. The reasons cited in literature for non-vaccination are: no risk of contracting a sexually transmitted infection, need for more information about the vaccine, immunobiological being new, decision to immunize the child and lack of medical indication (20) .
The development of the educational video of this study was based on a theoretical reference that determines that the production process is organized from three stages (8) . This foundation gave higher quality to the material, directing the steps to its composition. In accordance with this procedure, a video on chemotherapy treatment as an education strategy for cancer patients used a theoretical framework that specified the phases necessary for its elaboration: analysis and planning, modeling, implementation, assessment and maintenance and distribution (21) .
Validation of content provided scientific recognition that was associated with educational video. In it, all judges agreed that its content promotes adherence to vaccination, considering it suitable for use. Text comprehension and coherence of illustrations also obtained satisfactory scores, indicating that the information used is appropriate. The items related to these domains had a value of p > 0.05 and I-CVI > 0.80, proving that the use of the educational tool in practice is acceptable. A video on central venous catheter dressing also had the items properly assessed in the validation process, mainly regarding content and images, being considered apt to be available and useful in professional nursing training (22) .
Changes are common in the validation of educational materials. In this study, the value of S-CVI for video was 0.85, but the five items that presented I-CVI < 0.80 in validation of content were modified based on the suggestions made by the experts, making them more enriched and clearer. In the first scene, the proposal was of a livelier opening to awaken the attention of the viewer in its visualization, from the use of more attractive sounds and images, mainly by the younger age groups. Similarly, in the introduction of an educational video on oral hygiene of patients undergoing chemotherapy, changes were also suggested, all of which were adhered to and the modified script (23) .
The use of technologies that promote adherence to HPV vaccination is advocated by MoH in an attempt to focus efforts to guide the population on cervical cancer prevention (24) . In order to comply with this recommendation, the elaborated video is a strategy to disseminate knowledge about the subject, and may lead to the adoption of behaviors that result in immunization from the involvement of those who watch it. For this, the interest in the narrative increased with agility to the actions and the speeches that resemble the adolescent language, approaching its cultural environment. Thus, it can be used in educational actions, conquering the target audience and parents for immunization.
Video can be used in an interactive environment such as school, in order to enhance expression and communication, proposing a pedagogical action that generates learning (25) . Therefore, characters became more involved to captivate the target audience of the educational video, since the development of health themes in the school environment with the help of this tool, with the student community and the family, requires notable figures who are approaching and generate motivation. These adjustments, made in the production of the material, provided their adequacy to the proposed objective. Otherwise, there could be public disinterest and low video effectiveness at school and at other educational places.
Emotion and humor were best explored in the video to disclose the information of vaccination through entertainment in order to draw attention in an inviting, fun and gentle way. Communication force of images represents a superposition of sensory, visual, spoken, musical and written languages, reaching the senses, which facilitates the use of audiovisual in health education. It has the power to seduce, inform, entertain, transport to the imaginary, to other times and spaces (26) . Considering these considerations, the final version of the constructed video invested in images and sounds that sensitized to the vaccination, able to reproduce different sensations in its exhibition.
The validation of appearance verified the understanding of the items by the members of the population to which the educational video is destined. The inclusion of these participants contributed to material appropriateness, which will be used by others later, turning it into a more attractive, relevant, appropriate resource and that arouses greater interest of those who attend, from the implemented adjustments. With this same purpose, an educational video for teaching deaf students about cardiopulmonary resuscitation involved the participation of the target audience in their assessment (27) .
The insertion of video professionals in the validation of appearance gave more technical quality to the final version of the educational tool. This judgment raised some details previously unobserved and brought about coherent changes in its production and editing, collaborating to make it even more enriched. Likewise, qualified professionals were included in the technical assessment of an educational video for the prevention of childhood diarrhea (6) .
The version of the educational technology submitted to the validation of appearance had duration that framed it like video of social intervention, those that approach of 15 to 20 minutes (28) . The audiovisual was assessed as long, so it was decided to leave it with a duration of close to ten minutes, without there being any cuts in the contents, so as not to de-characterize it. In this question, it was considered that a very short video would make it impossible to convey knowledge deemed essential to achieve the proposed objective.
The relevance of the educational video was asserted by most participants in the validation of appearance as to the clarity of the scenes. The small adjustments, after this step, facilitated the transmission of the message, making it more. A similar situation was seen in the assessment of a short video to promote pneumococcus vaccination, in which the target public expressed positive reactions to their understanding and raised suggestions for their improvement (29) .

Study limitations
The educational video, constructed and validated in this study, was based on vaccination protocols made available by the SUS, with current information on HPV vaccine at the time of its elaboration and subsequent years. Therefore, its application in other countries may be limited, needing to adapt to the reality of certain places.

Contributions to Nursing, Health or Public Policy
The final version of the educational video will support educational actions aimed at girls, boys and parents in schools and health services about HPV immunization. As it is an educational technology, it will enable the facilitators of these activities to innovate ways to exchange knowledge with the public, favoring the construction and reconstruction of knowledge, instrumentalizing learning and contributing to the advancement of education. In addition, video is an educational material option for health education actions offered to the general population.
Guidelines on HPV vaccination should be part of the care provided by health professionals, including nurses, and educational activities at school. For this, an educational video about the subject, built under several eyes, can serve as a communication vehicle and cooperate in the improvement of vaccination rates.

CONCLUSIONS
The educational video with an emphasis on adherence to HPV vaccination, prepared with the participation of several actors involved in the subject, was validated as to the content among judges, and in appearance, with representatives of their target audience, educators and experienced professionals in audiovisuals.
However, it is important to note that new studies should be developed with the constructed material, such as randomized clinical trials, to verify its effectiveness in relation to immunization against the virus.