{'fraction_non_alphanumeric': 0.04044357469015003, 'fraction_numerical': 0.04370515329419439, 'mean_word_length': 5.111553784860558, 'pattern_counts': {'":': 0, '<': 1, '<?xml version=': 0, '>': 1, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Heart aging when near vision difficulty begins

Abstract Objectives Heart, lens, and neuronal cells change significantly with age, and they are older than cells from renewable tissues. Near vision deterioration during aging results from a decrease in accommodation amplitude (AA). Cardiac aging is an independent risk factor for cardiovascular disease. We investigated the association between cardiac aging and AA. Methods The subjects (500 mean 50-year-old subjects, with equal males and females) were divided into two groups according to AA measured with a Raf ruler. Biomicroscopy was used to capture images of the lens nucleus in the unaccommodated and accommodated state. The nucleus diameter change at 1 D accommodation was measured using ImageJ. Cardiac conduction system differences were evaluated using electrocardiography, and cardiac autonomic aging was assessed based on heart rate variability. Myocardial aging was assessed based on diastolic dysfunction. Results For near distance vision, compared to subjects who could see clearly from 24 to 28 cm, subjects who could see clearly from 29 to 33 cm had a 2.104-fold higher risk of a lateral e’ velocity <10 cm/s [95%CI: 1.312–3.374], 2.603-fold higher risk of diastolic dysfunction [95%CI: 1.453–4.662], 1.54-fold higher risk of a low/high frequency ratio >3.1 [95%CI: 1.085–2.197]. Conclusions As a simple screening test, subjective AA measurement can predict important heart aging parameters, including diastolic dysfunction. ClinicalTrials.gov Registry No NCT04362215