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Immunohistochemical Assessment of Hassall's Corpuscles in Human Foetal Thymuses

Hassall's corpuscles are unique component of the thymic medulla, which participate in the physiological activities of the thymus. Although, they have role in maturation and differentiation of thymocytes, their function still remains an enigma. Present study proposes immunohistochemical criteria for assessing structural and functional characteristics of Hassall's corpuscles using antibodies against cytokeratin markers in human fetuses.