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MR of multiple cranial neuropathies in a patient with camurati-engelmann disease: case report.

Camurati-Engelmann disease (progressive diaphyseal dysplasia) is a rare disorder of bone metabolism characterized by hyperostosis along the diaphysis of long bones [1-3] . It may also involve the skull and other membranous bone [1-3] . Cranial nerve deficits can be the most debilitating feature of this disease [3-7]. A narrowed foramen magnum can lead to brainstem compression and death [4, 6, 8]. Radiographic, CT, and MR findings demonstrate severe hyperostosis and sclerosis of the skull with almost complete obliteration of basal foramina and orbital apices. MR can directly demonstrate the course of the cranial nerves with respect to the stenotic foramina.