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Ultra-high-field (7.0 Tesla and above) MRI is now necessary to make the next step forward in understanding MS pathophysiology – Commentary

The mechanisms underlying the pathophysiological processes that lead to disease progression and disability in multiple sclerosis (MS) remain incompletely understood, and there remains a critical need for technologies that may facilitate exploration of central nervous system (CNS) tissue damage in people with the disease. In this controversies in MS, Bagnato and Gore advocate that ultra-high-field magnetic resonance imaging (MRI) is necessary to facilitate understanding of these mechanisms, while Jonkman counters that there is limited practical utility in this approach and our time and resources should be directed elsewhere.