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EVALUATION OF LEFT VENTRICULAR FUNCTION IN RATS TREATED WITH NANDROLONE DECANOATE SUBMITTED TO EXERCISE OF WEATHERED

There are several evidences of cardiovascular damage by use anabolic steroids androgenic (AAS). However, little is known about the cardiac effects of abusive use of AAS by women. Aim of this study was to evaluate the influence of Nandrolone Decanoate (ND) treatment over cardiac function in female rats submitted to a resistance exercise training. Female Wistar rats was divided in four groups (n=8): Sedentary vehicle (S), sedentary treated (SD), exercise vehicle (E) and exercise treated (ED). The animals were treated with ND (20 mg/kg/week) or vehicle (peanut oil) for 28 days, approved by the Ethics Committee in Animal Experimentation of the UFES (031/2012).