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Morphological pattern of the hypothalamo-neurohypophyseal system in acute intoxication with 2,4-dichlorophenoxyacetic acid [2,4-D].

The amount and distribution of the neurosecretory material in the hypothalamo-neurohypophyseal system were investigated in rats sacrificed 24 hours, 3 or 14 days after single intragastric administration of 2,4-D acid or physiological solution. The amount of the neurosecretory material increased in the whole system after 24 hours and then it decreased on the 3rd and on the 14th day after administration of 2,4-D acid.