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Dysplasia in chronic ulcerative colitis; more problems and few solutions.

Dysplasia in ulcerative colitis was defined as an unequivocal neoplastic change that is intraepithelial and within the confinement of the glandular basement membrane. Although that definition has stood the test of time and the classification is still the golden standard, the recommendations of treatment and follow up has significantly debated and changed. The purpose of this lecture is to outline the difficulties and controversies associated with dysplasia.