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THERAPEUTIC MANAGEMENT OF GASTROINTESTINAL COMPLAINTS IN CHILDREN INCLUDING PRELIMINARY EXPERIENCE WITH A NEW PEDIATRIC ANTACID PREPARATION

Gastrointestinal complaints are common in infants and children and can result from the reflux of stomach contents into the esophagus. Although the therapeutic management of these symptoms involves both nonpharmacologic and pharmacologic interventions, very few treatments have been designed specifically for a pediatric population. This report summarizes various therapeutic options for treating common gastrointestinal conditions and symptoms in pediatric patients. In addition, preliminary results are presented for a multicenter, open-label study of a new pediatric antacid preparation. We gave 321 children from 2–11 years old Children's MYLANTA Upset Stomach Relief to treat complaints of upset stomach associated with acid indigestion, sour stomach or heartburn, or overindulgence of food and drink during a 2-week period. The product was associated with high rates of effectiveness and acceptance by physicians, parents, and children. Children experienced substantial relief of their gastrointestinal symptoms within 1 hour of taking this new antacid, as evidenced by the large changes in symptom ratings that were performed before and after dosing. An extraordinary 95% of the physicians' ratings and 92% of the parents' ratings of the overall effectiveness of the medication were “excellent” or “good.” The pediatric antacid preparation was very well tolerated, with fewer than 5% of the children reporting side effects that could be considered at least possibly related to the medication. Thus, these preliminary results indicate that Children's MYLANTA Upset Stomach Relief-the first antacid specifically formulated for pediatric use—is well tolerated and highly effective in relieving common gastrointestinal symptoms in both young and older children.