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Desmopressin after cardiac surgery in bleeding patients. A multicenter randomized trial

Previous studies showed that desmopressin decreases post‐operative blood loss in patients undergoing cardiac surgery. These studies were small and never studied the effect of desmopressin in patients with active bleeding. Objective of the study was to determine whether desmopressin reduces red blood cells transfusion requirements in patients with active bleeding after cardiac surgery who had been pre‐treated with tranexamic acid.