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Descending outer medullary vasa recta are constricted by perfusion with iodinated contrast media

Contrast induced nephropathy (CIN) is a frequent complication of coronary angiography. Outer medullary descending vasa recta (DVR) are contractile microvessels supplying blood flow to the renal medulla ‐ the area of kidney at risk for CIN. Our objective was to test whether perfusion of DVR with a contrast medium (CM) modifies DVR vasoactivity.