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Dementias Platform UK (DPUK): Facilitating cross‐cohort analysis in a digital age

Dementias Platform UK (DPUK) is a £53M public‐private partnership established by the MRC to provide access to large‐scale cohort data and accelerate the research and discovery of new treatments for dementia. The DPUK Data Portal facilitates multi‐modal remote data access to 3.4M individuals from 42 cohorts using a secure, robust, persistent, and fully auditable data repository. To facilitate the analysis of multiple independent datasets, DPUK curates cohort data to the C‐Surv data model. This model standardises data structure, variable naming and value labelling conventions to reduce data pre‐processing times and reduce unwanted variation. C‐Surv also enables the harmonisation of datasets for analysis feasibility testing. We present the C‐Surv ontology and demonstrate its impact on data discovery and knowledge management for multi‐cohort, multi‐modal analysis in dementia research.