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Dose-escalation of locally advanced non-small cell lung cancer with proton beam therapy.

We appreciate the thoughtful comments by Drs. Hegde and Walker regarding the phase II study of concurrent chemotherapy and dose-escalated proton beam therapy (PBT) for locally advanced unresected non-small cell lung cancer (NSCLC) (1). There are several discussion points that we would like to add in tandem with the aforementioned correspondence.