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CD4+ T lymphocytopenia with disseminated HPV

Background:  There have been several reports of HIV‐negative patients with chronic idiopathic CD4+ T lymphocytopenia, the diagnostic criteria for which are: depressed numbers of circulating T lymphocytes (less than 300/µl or less than 20%) on more than one occasion; no laboratory evidence of HIV‐1 or HIV‐2 infection; and the absence of any defined immunodeficiency or therapy associated with depressed levels of CD4+ T lymphocytes.