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[Secondary hyperparathyroidism: comparison of clinical findings with the degree of early parathyroid hyperplasia (author's transl)].

Among 580 consecutive nonselected necropsies there were 145 cases of secondary hyperparathyroidism. In 74 instances blood concentrations of Ca2+, PO4(3-), urea, creatinine, total protein, albumin and alkaline phosphatase were available for comparison with the histomorpholgical degree of parathyroid hyperplasia matched with a control group of 32 patients with normal parathyroids. Analysis of variance revealed a significant difference in the levels of PO4 (3-) and creatinine between the normal group and that with minimal hyperplasia. Minimal and moderate diffuse parathyroid hyperplasia was associated with significant difference in calcium, phosphate, urea, creatinine, and total protein concentrations.