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Treatment of trichomonal vaginitis with a single dose of tinidazole.

SummaryA total of 64 patients suffering from trichomoniasis were treated with a single oral dose of 2.0 g. tinidazole or 2.0 g. metronidazole in a comparative study. Forty-three patients received tinidazole, and 21 patients metronidazole. In the tinidazole group, 3 therapy failures occurred; in the metronidazole group, 1 therapy failure was observed. Even though there was a small number of patients, the tolerance of tinidazole seemed to be slightly better than that of metronidazole. These results seem to correspond with those of other authors with regard to the effectiveness and the tolerance of the single-dose treatment of tinidazole in treating trichomonal infections. The results with this new dosage schedule are at least equivalent and perhaps even superior to the usual 7-day treatment regime.