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Reduction of cholesterol transported in apo B-rich lipoproteins in spontaneously hypercholesterolemic hamsters fed an apple-supplemented diet.

The influence of an apple-supplemented diet on the distribution of cholesterol among the lipoproteins in plasma was studied using a special animal model: FEC hamsters which spontaneously develop hypercholesterolemia with aging when fed a commercial balanced diet. This metabolic disorder did not occur in animals freely consuming apples in addition to the standard diet. This combined diet essentially decreased the cholesterol content in the VLDL and LDL, the apo B-rich lipoproteins in plasma.