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Main line patterns of palmar dermatoglyphics in female breast cancer patients

Our study covered 82 females with clinically, histologically and mammographically proved breast cancer and 60 healthy controls of Bulgarian ethic origin. Their age distributions in 10-year intervals were juxtaposed in Figure 1. The patients were hospitalized and operated on in the Clinic of Thoracic Surgery, St. Marina University Hospital of Varna, during the period between January 1, 2014 and December 31, 2017.


Introduction
In the recent decades, several articles deal with dermatoglyphic investigations in breast cancer patients. [2][3][4][5][6] Fingerprint research prevails over palmar dermatoglyphics. However, specific palmar patterns such as ridge count, ATD angles and A, B, C and D main lines represent an integral component of diagnostic and prognostic armamentarium in female breast cancer patients.
Our purpose was to examine the differences between breast cancer females and healthy controls in terms of the A, B, C, and D main line palmar characteristics as a possible prognostic tool for breast cancer risk evaluation.

Material and methods
Our study covered 82 females with clinically, histologically and mammographically proved breast cancer and 60 healthy controls of Bulgarian ethic origin. Their age distributions in 10-year intervals were juxtaposed in Figure 1
The frequencies of the main lines B and C of the left hand did not differ statistically reliably between breast cancer females and healthy controls (χ 2 =2,00; p=0,156 and χ 2 =2,21; p=0,137, respectively).
A template-based image preprocessing as a functional plug-in of the dermatoglyphics analysis and detection system was developed. 9 It included histogram redistribution, ridge orientation, and skeletonization for automatic identification of ridges and triradiuses. This system could be applied as an auxiliary diagnostic tool for mammary cancer and other hereditary diseases.

Conclusion
Based on our own data demonstrating statistically significant differences between breast cancer patients and healthy women concerning the frequencies of main palmar lines A and D as well as on scanty literature data available we could draw the conclusion that dermatoglyphic research dealing with these main palmar lines deserves a particular attention as an additional valuable prognostic tool for risk stratification in women suspected for breast cancer.