{'fraction_non_alphanumeric': 0.020046260601387818, 'fraction_numerical': 0.018504240555127217, 'mean_word_length': 5.240384615384615, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Effect of chronic electrical stimulation on incorporation of [1‐14C]oleate into glycerolipids of mouse brain

WE HAVE previously demonstrated that when labeled fatty acids are injected intracerebrally into the mouse brain. they are metabolized rapidly and incorporated into various membrane glycerolipids (SUN & HORROCKS, 1971; YAU & SUN. 1973. 1974). The free fatty acid pool in brain is probably maintained at a low level through dynamic equilibration between the free and esterified form. A disturbance of the equilibrium during traumatic conditions such as ischemia and electroconvulsive shock may result in a rapid increase in brain free fatty acid level (BAZAN & RAKOWSKI, 1970; BAZAN. 1970). However, the effects of external stimuli and stress on metabolism of the free fatty acids in brain and their incorporation into glycerolipids have not been investigated. In the present experiment, we will describe the metabolism of labeled oleate injected intracerebrally into controls and a group of mice which have been subjected to intermittent electrical stimulation for 2 weeks. Special emphasis is made with regard to a comparison of the turnover of labeled oleate in brain and the uptake or labeled oleate by various glycerolipids in controls and in mice subjected to electrical stimulation.