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RESUSCITATION OF HYPOXIC NEWBORNS WITH ROOM AIR OR OXYGEN

To study the short term effects of resuscitation of hypoxic newborn babies with room air, a randomized multicenter study was initiated. Here the data from one center is reported. Entry criteria were: birth weight > 1000 gram, heart rate at birth < 80 per min and or apnoe justifying resuscitation. This was performed with bag and mask or after endotracheal intubation when needed. Babies were enrolled into a group treated with room air (RA, N=36) or 100% oxygen (O2, N=42). Babies in RA group who did not respond within 90 seconds were treated with supplementary oxygen.Heart rate from birth to 10 minutes and Apgar scores from 1 to 20 minutes were identical in both groups as well as pH, BE, paO2 and paCO2 at 10 and 30 minutes post partum. Neonatal mortality was 2/36 in RA and 4/42 in O2 groups (NS) respectively. The study shows that judged by short term follow up hypoxic newborn infants may be resuscitated with room air just as well as with 100% O2.