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Effect of Aldrin on Accessory Sex Glands and Plama Testosterone Levels in Rats/Der Einfluß von Aldrin auf die akzessorischen Geschlechtsdrüsen und die Plasma‐ Testosteron‐Werte der Ratte

Summary: The effects of aldrin, an organochlorine insecticide, on accessory sex glands and plasma testosterone levels in rats were studied. The aldrin was administered i.p. for 13 days and 26 days at a dose of 150 μg/kg. Relative weights of prostate, seminal vesicles and coagulating glands were significantly decreased in the treated rats compared to those in controls. In addition, there was a significant fall in acid phosphatase activity in prostate and fructose content in accessory sex glands was also observed in treated animals. Plasma testosterone values showed a decrease with the duration of treatment. HCG supplementation with aldrin treatment prevented all those untoward effects of aldrin in experimental rats.