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[The association of limited health literacy and risk of arterial stiffness in community-dwelling older adults].

AIM
This study aimed to investigate the effects of limited health literacy on arterial stiffness measured by the cardio-ankle vascular index (CAVI) in community-dwelling older adults.


METHODS
A total of 288 older adults (mean age, 72.4 years, men, n = 99) participated. The degree of arterial stiffness was assessed based on the CAVI using the VS-1500 device (Fukuda Denshi Co., Ltd., Tokyo, Japan). Arterial stiffness was defined according to a cut-off point of ≥9.0. Comprehensive health literacy was assessed using the 47-item European Health Literacy Survey Questionnaire (HLS-EU-Q47). Other potential confounding factors, such as demographics, number of prescribed medications, mini-mental state examination results, grip strength, gait speed, current smoking, alcohol consumption, and physical inactivity, were also assessed. An analysis of variance for continuous variables or chi-square test for categorical variables was used for group comparisons. A logistic regression analysis was performed to examine the association between quartiles of HLS-EU-Q47 and arterial stiffness in crude and multivariate models adjusted for age, gender, and other confounding factors.


RESULTS
The first quartile with the lowest health literacy showed a significantly higher CAVI and prevalence of arterial stiffness than the fourth quartile with the highest health literacy (p<0.05). In logistic regression, the crude model showed that the third quartile (odds ratio [95% confidence interval] = 0.48 [0.24-0.93]) and fourth quartile (0.39 [0.19-0.77]) were significantly associated with arterial stiffness, while the multivariate model showed that to fourth quartile was significantly associated with arterial stiffness (0.44 [0.19-0.98]).


CONCLUSIONS
Older adults with limited health literacy might be at a higher risk of arterial stiffness after accounting for confounding factors.