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Isotretinoin (Accutane) and pregnancy.

How long does isotretinoin stay in the body? How long after a woman stops taking isotretinoin should she wait to become pregnant? The time it takes isotretinoin to be cleared from the blood varies. Usually, isotretinoin is no longer found in a woman’s blood 4-5 days after the last dose. Most of its by-products should be gone within 10 days after the last dose. It is recommended that a woman wait one month after stopping isotretinoin before trying to become pregnant.