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The bacteriological environment of preterm infants.

Bacteria were cultured in the intra-uterine environment in 72% of 56 preterm infants studied. Placental tissue yielded the greatest number of positive cultures, with anaerobic organisms accounting for one-quater of these. Bacterial growth was obtained in the specimens of 4 out of 5 infants who died, and in 5 clinically infected babies. The incidence of bacterial infection was not increased by rupture of membranes for more than 18 hours, by amniocentesis or by administration of dexamethasone to the mother.