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Chemotherapy and immunosupression of kidney transplant recipients.

Little progress has been made in immunosuppressive therapy for kidney transplant patients in the last decade. A more rational approach to investigation, both experimentally and clinically, is needed so that available immunosuppressive agents can be used with maximum effectiveness and minimal side effects. Well-designed, randomized, prospective multicentre trials must be performed in the future if we are to obtain definitive answers.