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Meta-Analysis of Safety and Efficacy of Different Radical Gastrectomy in the Treatment of Gastric Cancer

To investigate the safety and efficacy of different radical gastric cancer treatments in the management of gastric cancer. The literature published in the last 5 y was searched for recent outcomes of different radical gastric cancer procedures used in the treatment of gastric cancer. 14 papers were finally included according to the established screening criteria. The trial design, study population characteristics and findings of the included studies were abstracted using randomized independent trials and statistically analyzed using RevMan 5.0 software. The results of the meta-analysis showed that laparoscopic early distal gastric cancer surgery compared with conventional open surgery: The operative time was 49.85 min longer (p<0.05), but intraoperative bleeding was 145.50 ml less (p<0.05), the number of postoperative analgesic requests was 1.22 less (p=0.01) and the number of days to the first postoperative vent was 0.57 d shorter (p<0.05), the number of days to the first postoperative meal was shortened by 0.88 d (p<0.05); the number of postoperative hospital days was shortened by 4.76 d (p<0.05) and the incidence of postoperative complications was low, both differences were statistically significant (p<0.05). The recent efficacy of laparoscopy-assisted distal gastrectomy in treating gastric cancer was significantly better than that of conventional open distal gastrectomy.