{'fraction_non_alphanumeric': 0.02332814930015552, 'fraction_numerical': 0.011404872991187144, 'mean_word_length': 5.5646258503401365, 'pattern_counts': {'":': 0, '<': 2, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Protocol Summary of the CAPTURE Validation in Primary Care Study.

COPD often remains undiagnosed and untreated. To date COPD screening/case finding has not been designed to identify clinically significant COPD, disease ready for therapies beyond smoking cessation. Herein we describe the ongoing prospective, pragmatic cluster-randomized controlled trial to assess specificity and sensitivity of the CAPTURE (COPD Assessment in Primary Care To Identify Undiagnosed Respiratory Disease and Exacerbation) tool consisting of five questions and peak expiratory flow. The tool is designed to identify clinically significant COPD (FEV1/FVC <.7 plus FEV1% predicted <60% or increased for exacerbation) and explore the impact of CAPTURE-based screening on COPD diagnosis and treatment rates in primary care patients. Of a total planned enrollment of 5000 English- or Spanish-speaking patients ages 45 to 80 years without a prior COPD diagnosis from 100 primary care practices, 68 practices and 3064 patients have been enrolled. Practices are centrally randomized to either usual care or clinician receipt of patient-level CAPTURE results. All clinicians receive basic COPD education with those in intervention practices also receiving CAPTURE interpretation education. In a single visit, patient participants complete CAPTURE screening, pre- and post-bronchodilator spirometry and baseline demographic, and health questionnaires to validate CAPTURE sensitivity, specificity, and predictive value of identifying undiagnosed, clinically significant COPD. One-year follow-up chart reviews and participant surveys assess the impact of sharing versus not sharing CAPTURE results with clinicians on clinical outcomes; level of respiratory symptoms and events and clinicians' initiation of recommendation-concordant COPD care. This is one of the first U.S. studies to validate and assess impact of a simple COPD screening tool in primary care.