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Dispersal of pathogen‐associated multispecies biofilm by novel probiotic Bacillus subtilis in a contact‐dependent manner

Biofilms are involved in pathogenesis of various bacterial infections. Treatment of biofilm‐related bacterial infection remains a major challenge due to the reduced efficacy of antibiotics and associated antibiotic resistance. Given the high prevalence of Enterotoxigenic Escherichia coli (ETEC), Salmonella Typhimurium (S. Typhimurium) and methicillin‐resistant Staphylococcus aureus (MRSA)‐related infections and associated drug resistance, it is imperative to develop alternative strategies for treatment and prevention. The current study investigated antibiofilm activity of a recently isolated Bacillus subtilis (B. subtilis‐9) against these pathogens.