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Liver transplantation in biliary atresia with concomitant hepatoma.

Congenital biliary atresia ranks high in the candidacy list for hepatic transplantation, and constitutes the single most frequent indication for liver replacement in a series reported from our institution.25 In 2 patients treated in this manner, hepatoma was present in the cirrhotic livers, excised at the time of transplantation. The diagnosis of hepatoma had been made pre-operatively in 1 instance, but in the other the finding of a tumour in the specimen was a surprise. 
 
The occurrence of primary liver cell carcinoma in livers with pre-existing cirrhosis due to congenital biliary atresia is unusual. Absolon first mentioned this association in a report on thoracic duct lymph drainage for bile duct atresia.1 Three cases were subsequently reported by Okuyama.20 Fish10 and Deoras.7. 
 
This communication reports on the 2 above-mentioned cases of congenital biliary atresia with concomitant hepatoma treated by hepatic replacement.