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A COMPARATIVE STUDY OF ABG PATTERN IN PATIENTS OF COPD WITH OR WITHOUT COR PULMONALE

INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is a major public health problem. COR PULMONALE describes the
enlargement and failure of the right ventricle of the heart as a response to increased vascular resistance or increased pulmonary artery pressure.
Hypoxic pulmonary vasoconstriction, hypercapnia, respiratory acidosis and pulmonary vascular remodeling in COPD can cause an increase in
right ventricular (RV) after load, which in turn, results in RVfailure leading to COR PULMONALE
AIM:The purpose of the study is to compare the ABG pattern in patients of COPD with or without COR PULMONALE.
MATERIALS AND METHODS: This prospective observational study was conducted in the Department of Medicine of DMCH, Laheriasarai,
Bihar. The study was conducted with duration of 2 years. Atotal of 100 patients admitted as a case of COPD with or without COR PULMONALE.
The patients were put into two subgroups, COPD with and without COR PULMONALE.
RESULT: The mean duration was 10.17 years and 9.20 years respectively in patients with and without COR PULMONALE. There was no
statistically signicant difference regarding mean duration of disease (p value =0.304). Mean CAT score was 16.59 ± 6.26 and mean mMRC was
3.19± 0.45 in COPD patients with COR PULMONALE group. Mean CAT score was 14.06 ± 4.46 and mean mMRC was 3.10 ± 0.44 in COPD
patients without COR PULMONALE group. We found no signicant difference among these variables between groups. Although COR
PULMONALE patients had higher CATscore and mMRC score, the difference was not signicant (p value = >0.05).
CONCLUSION:ABG ANALYSIS should be recommended for all patients of COPD with or without COR PULMONALE to assess the degree of
hypoxemia, hypercapnea, respiratory acidosis and also, we can identify individuals who need more close monitoring and intensive treatment.