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Endoscopic machine vision system for blood-supply estimation of the nasal mucosa

We have developed a machine vision system, which combines imaging and absolute color measurement techniques, for remote, objective, 2D color and color difference measurements. This imaging colorimeter adapted on an endoscope was used to evaluate nasal mucosa color changes induced by the administration of a sympathomimetic agent, with vasoconstrictive properties. The demonstrated reproducible and reliable measurements indicate the efficacy of the described system, for the potent vasoconstriction assessment of different pharmacotherapeutic agents, and suggests that it can also be useful for evaluating individuals, with allergic rhinitis, vasomotor rhinitis, and inflammation disorders of the paranasal sinuses. Machine vision techniques in endoscopy providing objective indices for optical tissue characterization and analysis can serve in understanding the pathophysiology of tissue lesions, and in the objective evaluation of their response to different therapeutic schemes, in several medical fields.