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Tissue‐preserving approach to extracting DNA from paraffin‐embedded specimens using tissue microarray technology

DNA extracted from tumor cells or normal cells contained in formalin‐fixed, paraffin‐embedded tissues is widely used in many laboratories. The 2 most common procedures to isolate cells for DNA extraction from paraffin‐embedded tissues are scalpel microdissection and laser capture microdissection. A new tissue‐ and time‐conserving method for rapid DNA isolation from small cores taken from paraffin‐embedded tissue blocks is described in this report.