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Behavior phenotype of the fragile X syndrome.

The publication of 2 studies in this issue of the Journal [Fisch, 1992; Reiss and Freund, 1992] on the relationship between the fragile X [fra(X)] and autistic syndromes provides an appropriate time to review the continuing debate about whether or not there is a relationship between these 2 syndromes. We examine the evidence on the relationship between the autistic and fra(X) syndromes, and briefly describe reported evidence of other aspects of behavior phenotype of this syndrome