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[Incidence of chronic diseases in families of allergic children with recurrent infections].

An incidence of the chronic ailments has been determined in families of allergic children with recurrent infections. Typical allergic disorders and syndromes, including infantile eczema in the first year of life (48.0% of children), and positive skin prick tests (52.0%), have been characteristic for this group of children. Moreover, cell-mediated immunological deficit has been seen in 37.0% of these children, humoral immunological disorders--in 23.0%, and phagocytosis disturbances--in 30.0% of children. Sixty five percent of the examined children has been hospitalized from 1 to 10 times and more. A percentage of children being sick at home for 1 month and longer has been similar. The following diseases have been detected in the population of 1,049 parents and the I line relatives of these children: allergic diseases--mainly bronchial asthma in 16.0%; neoplasms in 9.8%; arterial blood hypertension in 5.1%; tuberculosis in 2.6%; duodenal or peptic ulcers in 2.6%; rheumatoid disorders in 2.5%; diabetes mellitus in 1.9%, and psoriasis in 1.1%. Statistically significant differences (0.01 > p > 0.001) between an incidence of the allergic disorders, mainly bronchial asthma, and neoplastic diseases has been found in the examined population of parents and relatives of allergic children with recurrent infections and general population. Such a result suggest similarity of the probable immunological dysfunction in both groups.