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To compare efficacy of tamsulosin versus tamsulosin with tadalafil in lower ureteral stones as the medical expulsive therapy for lower ureteric stone: A randomized trial

Methods: Between Jan 2013 and Dec 2013, 244 patients presenting with distal ureteric stones of size 5 to 10 mm were randomized equally to tamsulosin (group A), tamsulosin with tadalafil (group B). Therapy was given for a maximum of four weeks. Stone expulsion rate, time to stone expulsion, analgesic use, number of hospital visits for pain, follow-up and endoscopic treatment and adverse effects of drugs were noted. Statistical analyses were done using Student’s t test and Chi-square test.