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Demographic and clinical characteristics of extramammary Paget's disease patients in Japan from 2000 to 2019

Extramammary Paget's Disease (EMPD) is a rare adenocarcinoma that arises in apocrine gland-bearing skin and is associated with increased risk of underlying or distant malignancies. The demographic and clinical characteristics of biopsy-confirmed, newly diagnosed EMPD patients from 2000-2019 were analyzed across 7 institutions in Japan. Indeed, 544 patients were identified, of which 327 (60.1%) of patients were males and 217 (39.9%) patients were females; the male-to-female incidence ratio was 1.5:1.0. The mean age at diagnosis was 72.1±11.3 years for males and 72.2±10.6 years for females. Invasive EMPD were more diagnosed in males (55.4% versus 39.2% in females).