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Cytomegalovirus Retinitis as the First Manifestation of Good Syndrome

Good syndrome, first described by Robert Good in 1954, is an extremely rare disease associated with hypogammaglobulinemia and concurrent thymoma. In general, the symptoms associated with Good syndrome are caused by systemic opportunistic infection. Although there have been several case reports of cytomegalovirus (CMV) retinitis in Good syndrome, there have been no reports of Good syndrome first recognized by the development of CMV retinitis. Herein, we report a case of hypogammaglobulinemia and thymoma that presented with CMV retinitis as the first manifestation of Good syndrome, with no evidence of other systemic infection.