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CHANGES IN SUSCEPTIBILITIES TO INSECTICIDES IN MUSCA DOMESTICA UNDER SELECTION
WITH FIPRONIL

New knowledge about resistance and cross-resistance to insecticides of different chemical classes in insects is crucial for correct and effective pest management. This paper reports changes in the susceptibility to insecticides of different chemical classes in the first generations of houseflies Musca domestica L. when they were selected with fipronil. The selection of M. domestica was carried out by feeding adult insects with sugar containing fipronil in a dose that causes the 40–60% mortality of insects. The susceptibility of adults and larvae to insecticides was evaluated by the resistance ratio (RR). In the fipronil-selected strain of M. domestica, the susceptibility to fipronil was unchanged in adults in 3–5 generations and increased in larvae in the fifth generation (RR = 0.5). The susceptibility to deltamethrin decreased in adults of the fourth generation and in larvae of the fifth generation, and the RR was 4.5 and 4.3, respectively, that may suggest the development of cross-resistance in the future. The susceptibility to chlorfenapyr was reduced in adults of fipronil-selected flies of the fourth generation (RR = 1.9). The susceptibility to ivermectin increased in adults of fipronil-selected flies (RR = 0.67) and in larvae of the fifth generation (RR = 0.5). The susceptibility to acetamiprid in the fipronil-selected strain and the laboratory (unselected) strain of M. domestica did not differ. The results are useful for the development of insecticide resistance management programs.