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[A case report of primary duodenal adenocarcinoma with marked lymph node metastases responding to chemotherapy with S-1 plus CDDP combination].

The patient was a 48-year-old female who underwent combination chemotherapy of S-1 plus CDDP after diagnosis of primary duodenal adenocarcinoma with marked lymph node metastases. The regimen was as follows: 80 mg/m2 of S-1 on days 1-21 orally and 60 mg/m2 of CDDP on day 8 intravenously. One course lasted for 5 weeks. After 5 courses, metastasized lymph nodes were remarkably reduced. This case suggests that the combination of S-1 and CDDP may be an effective regimen for advanced primary duodenal adenocarcinoma.