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Sperm protein 17 and AKAP‐associated sperm protein cancer/testis antigens are expressed in ciliated hepatic foregut cysts

Ciliated hepatic foregut cysts (CHFCs) are retained benign lesions of the liver. However, a case of squamous cell metaplasia and five cases of squamous cell carcinoma arising from a CHFC have been described. The potential of malignant transformation makes the identification of new biomarkers necessary. As the cancer/testis antigen sperm protein 17 (Sp17) has been detected in oral and oesophageal squamous cell carcinomas, the aim of this study was to investigate the expression of Sp17 and AKAP‐associated sperm protein (ASP), which has a shared N‐terminal sequence with Sp17, in four surgically resected CHFCs.