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The Structure and Function of Experimental Control in the Life Sciences

This article presents a new framework for the analysis of experimental control. The framework highlights different functions for experimental controls in the realization of an experiment: experimental controls that serve as tests and experimental controls that serve as probes. The approach to experimental control proposed here can illuminate the constitutive role of controls in knowledge production, and it sheds new light on the notion of exploratory experimentation. It also clarifies what can and what cannot be expected from reviewers of scientific journal articles giving feedback on experimental controls.