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Chromium status of tannery workers in relation to metabolic disorders

Chromium (Cr), being an excellent tanning agent, is widely used in the leather industry. In the process of leather production, tannery workers are exposed to either inorganic Cr(III) compounds or Cr bound to proteins (leather dust). The total Cr content in tannery air (1–54 μg m−3) is rather high in comparison to ambient air (4–6 ng m−3) but the amount of Cr in inhalable particles (<10 μm) is two to three orders of magnitude less (20–60 ng m−3). The total daily intake of Cr was estimated by the analysis of diet (24.3 ± 4.0 μg Cr day−1), drinking water (0.3 ± 0.1 μg Cr dm−3) and ambient air. The contribution of the latter was dominant for tannery workers and almost negligible (8%) for the unexposed population.