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Synthesis of Biological Active Chromene Benzothiadiazole Derivatives

In this article, we describe the synthesis of various substituted Chromene-[1, 3]thiazolo [2, 1, 3] benzothiadiazoles 4a-l by conventional (Method A) and microwave-assisted (Method B) which achieved reductions in reaction times, higher yields, and a cleaner reaction than the conventional method. A comparative study of these two methods has been discussed.