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ALK and ROS1 rearrangement tested by ARMS‐PCR in non‐small‐cell lung cancer patients via cytology specimens: The experience of Shanghai Pulmonary Hospital

Cytology specimens are the main samples used for the diagnosis of advanced lung cancer. The objective of our study was to assess anaplastic lymphoma kinase (ALK) and c‐ros oncogene 1 receptor tyrosine kinase (ROS1) genes by an amplification refractory mutation system (ARMS)‐polymerase chain reaction (PCR) using cytology specimens and to then evaluate the mutation frequency of ALK and ROS1 in non‐small‐cell lung cancer (NSCLC) patients.