{'fraction_non_alphanumeric': 0.019307211811470756, 'fraction_numerical': 0.0034071550255536627, 'mean_word_length': 5.338129496402877, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Metabolic Investigation in Hepatitis B Patients with or Without Diabetes mellitus to Determine the Impact of Anti-Oxidant Activity

To determine the impact of antioxidant activity by metabolic investigations in hepatitis B patients with or without diabetes mellitus. Fifty patients each were included in this study with chronic hepatitis B and 50 HBV patients with diabetic mellitus. Eligibility criteria included: HBsAg, HBeAg and HBV DNA positivity in blood for six months or more; elevation of serum aspartate aminotransferase or alanine aminotransferase levels for six months or more and exclusion of co-infection with hepatitis delta or acquired immunodeficiency virus, metabolic or autoimmune disorders. All subjects underwent blood testing after a 10-h overnight fast to measure serum levels of fasting plasma glucose, total cholesterol, triglyceride and alanine aminotransferase. The subjects were also assessed for urea, creatinin, copper, zinc and magnesium and total anti-oxidative activity was measured by reducing Fe+++ to Fe++ using vitamin c as reducing agent at pH 4 to 5. The urea, uric acid and creatinine levels are significantly increased in HBV, cholesterol (total, HDL and LDL) all decreased in HBV patient where as triglyceride levels significantly increased in HBV patients with DM. The AST increases significantly in both groups of HBV patients. Magnesium is significantly decreased in diabetic HBV patients and unchanged in HBV patients. Iron is increased and zinc is decreased in both groups of HBV patients. Additional factors in elevated level of iron resulting into low antioxidative activity. Urea and creatinine levels are significantly increased that shows not only heart and pancreas but kidney can be affected in HBV patients.