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Reversed changes of lipoxin A4 and leukotrienes in children with asthma in different severity degree

To investigate the expressions of 15‐lipoxygenase (15‐LO) and 5‐lipoxygenase (5‐LO) in leukocytes and the changes of blood lipoxin A4(LXA4), leukotriene (LT)B4 and LTC4 in children with asthma, and to explore the relationship between the blood eicosanoids and one of serum high‐sensitivity C‐reactive protein (hsCRP), interleukin (IL)‐5, IL‐8 and IL‐13 and IgE in children with asthma.