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Biosafe Ginseng: A Novel Source for Human Well‐Being

Given the enormous biodiversity in field cultivation, bioengineers were only to look within nature to find new promising phytomolecules or biochemical pathways from plant biofactories. The present review discusses pilot‐scale bioreactor cultivation of adventitious roots of ginseng and the enhanced production of pesticide‐free bioactive phytomolecules. This biotechnological method is described together with a discussion on economic and biosafety aspects. Besides the “classical” tissue culture as a subject of research on ginseng, new developments and efforts in pilot‐scale bioreactor tissue modeling and in the generation of artificial adventitious roots are considered. Additionally, recent progress in the field of medicinal and nutritional roles of adventitious roots produced in a pilot‐scale bioreactor are discussed.