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[Histological evaluation of aimed gastrobiopsy in the diagnosis of early stomach cancer].

Among 81 patients with malignancies of the stomach, the early (cancer of the gastric mucosa) was diagnosed in 10 (12.3%) patients. Timely diagnosis of the early gastric cancer requires multiple endoscopic examinations and aimed gastric biopsies of the edges and bottom of the ulcer. The analysis of the serial histological preparations permits to detect single or small aggregations of large mucous cells looking like cricoid cells (considered by the author as a sign of malignization) and less frequently like tumour tissue, in necrotic mass or in the proper layer of the mucous membrane. It is recommended that any gastric ulcer be considered as a possible ulcerative form of cancer and that the patients be mandatorily examined in specialized institutions where the differential diagnosis between peptic ulcer and ulcerative form of cancer may be performed by the method of gastroscopy with aimed biopsy.