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Nutritional regulation of epigenetic changes.

The “Nutritional Regulation of Epigenetic Changes” Symposium was held in San Diego on April 25 in conjunction with the 2012 Annual Meetings of the American Society of Nutrition. The symposium was co-chaired by Drs. Romagnolo and Ziegler. In his opening remarks, Dr. Zeigler highlighted salient aspects of epigenetic regulation, i.e., the study of heritable changes in gene function that occur without a change in DNA sequence. Epigenetic mechanisms include changes in expression and interactions of noncoding RNA with target mRNA, histone modifications, and DNA methylation at CpG islands.