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Numerical simulations of edge detection effect due to chemical shift variation in intermolecular multiple-quantum coherence MRI

Combined with the theories of intermolecular multiple-quantum coherences (iMQCs) and distant dipolar field (DDF) effect, edge detection effect due to chemical shift variation in magnetic resonance imaging (MRI) was simulated and discussed deeply using an efficient numerical algorithm based on the nonlinear Bloch equations. Simulation results show that, different from the conventional MRI signal, chemical shift in iMQC MRI can provide new imaging information, an edge detection method to search regions containing spins with chemical shift offset. The edge detection method can present plentiful information about various kinds of edges of object regions.