{'fraction_non_alphanumeric': 0.019430051813471502, 'fraction_numerical': 0.0, 'mean_word_length': 4.856060606060606, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
A Surprising Function for the PTEN Tumor Suppressor

CANCER RESEARCHCancer researchers believed that the protein product of the tumor suppressor gene PTEN , discovered last year, might suppress tumor cell growth by stripping off phosphate groups attached to tyrosine residues in other proteins. Now, a flurry of new work is showing that PTEN is a phosphatase, but its target is a fatty molecule, or lipid, that's tucked into the cell membrane--a completely new kind of target, as far as tumor suppressors are concerned. The target lipid is a key component of one of the cell's major growth control pathways; this knowledge could aid the development of treatments for cancers in which PTEN is mutated or in which this growth control pathway is overactive for other reasons.