Regulatory Network in Protein Phosphorylation

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Kinase: MAP2K7 mitogen-activated protein kinase kinase 7

Group: STE      Family: STE7      Subfamily: MEK7

Description: mitogen-activated protein kinase kinase 7

Gene Symbol: MAP2K7

Synonyms: Jnkk2, MAPKK7, MKK7, PRKMK7

UniprotKB/SwissProt: MP2K7_HUMAN (O14733)

Function: Stress activated, dual specificity kinase that activates the JUN kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3.

Subcellular Localization: Nucleus. Cytoplasm (By similarity).

Protein Domain:

The substrate proteins of kinase MAP2K7

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1MAPK8MK08_HUMANMitogen-activated protein kinase 8 (EC (Stress-activatedprotein kinase JNK1) (c-Jun N-terminal kinase 1) (JNK-46). 3Show
2MAPK9MK09_HUMANMitogen-activated protein kinase 9 (EC (Stress-activatedprotein kinase JNK2) (c-Jun N-terminal kinase 2) (JNK-55). 7Show
3MAPK10MK10_HUMANMitogen-activated protein kinase 10 (EC (Stress-activatedprotein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p493F12). 1Show