
Gene October 31, 1996; 178 (1-2): 111-4.

Isolation of a cDNA encoding the X enopus homologue of mammalian Cdc25A that can induce meiotic maturation of oocytes.

Okazaki K , Hayashida K , Iwashita J , Harano M , Furuno N , Sagata N .

From a cDNA library of Xenopus laevis (Xl) oocytes, we isolated a cDNA encoding a putative protein phosphatase homologous to mammalian Cdc25A. Sequence analysis predicts that the Xl cdc25A gene product (Xl Cdc25A) consists of 521 amino acid residues and shares overall 55% identity with human Cdc25A. When its mRNA is injected into Xl oocytes, Xl Cdc25A can act as a potent M phase inducer.

PubMed ID: 8921900
Article link: Gene

Genes referenced: cdc25a

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