Important Functions of the Methylation Cycle


  1. To produce glutathione.  Glutathione is the primary detoxification protein that protects the body from toxins and free radicals.
  2. To regulate and detoxify sulphur metabolism. Important molecules containing sulphur include glutathione, methionine, SAMe, homocysteine, taurine, sulphite and sulphate. Sulphur can be toxic when not properly metabolized.
  3. To produce and recycle biologically active folic acid. Folic acid is necessary for the production and maintenance of new cells and has been implicated in a wide range of disease states.
  4. To metabolize neurotransmitters. Neurotransmitters including glutamate, dopamine, serotonin, epinephrine and norepinephrine.
  5. To regulate DNA and RNA expression. Methyl groups act as an “on/off” switch for DNA and RNA. This is important for the synthesis of proteins, as well as a protective mechanism against viral infections.
  6. To produce myelin for the brain and nervous system. Myelin is like insulating rubber on an electrical wire.  It covers nerves and keeps signals from dissipating as they travel through neural networks.
  7. To produce Coenzyme Q10 and carnitine.  These are mitochondrial enzymes that are vital to your energy (ATP) supply.
  8. To regulate protein activity. Proteins include hormones, neurotransmitters, enzymes and immune factors that are fundamental to good health.

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