Temple is back and this time, Daniel is in even deeper trouble. In the first season, he just about kept the plates in the air as he looked after his wife, Beth, in an illicit clinic underneath Temple tube station.

But now everything comes crashing down as Beth wakes from her coma and demands answers. Eve wants to know why her parents have been lying to her, Lee joins forces with a charismatic activist and Anna is desperate to make something positive out of the situation, even if that means luring patients to the bunker for some illegal trials.

Mark Strong, Carice van Houten, Daniel Mays, Catherine McCormack, Lily Newmark, Ryan McKen and Tobi King Bakare return and are joined by new faces as the story continues in dramatic and unexpected ways. Amongst the new arrivals are dubious and deeply unpredictable underworld fixer Gubby, played by BAFTA-winner Rhys Ifans and his poetic but frequently inebriated medical assistant, Dermot, played by Michael Smiley. Also joining are BIFA-winner Ruthxjiah Bellenea , Mandeep Dhillon, Jamie Michie, Will Keen and Bafta winner Gbemisola Ikumelo.