Table 3

Multivariable analysis of CDAI over time

Coeff95% CIP values
TCZ mono vs TNFi combo0.17−1.33 to 1.660.83
TNFi mono vs TNFi combo−0.23−1.06 to 0.600.59
TCZ mono vs TCZ combo−0.21−1.24 to 0.830.70
TCZ mono vs TNFi mono−0.47−1.60 to 0.660.41
TCZ combo vs TNFi combo0.09−0.56 to 0.740.79
TCZ combo vs TNFi mono0.21−0.74 to 1.160.67
  • Adjusted by age, gender, disease duration, seropositivity, number of previous biologic disease-modifying antirheumatic drugs, glucocorticoids at baseline, Health Assessment Questionnaire at baseline.

  • Coeff, coefficient; combo, combination therapy; mono, monotherapy; TCZ, tocilizumab; TNFi, tumour necrosis factor inhibitor.