

midazolam (oral)

Pronunciation: mye DAZ oh lam

Brand: Versed

What is the most important information I should know about midazolam?

Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication. Midazolam is given in a hospital, dentist office, or other clinic setting where your vital signs can be watched closely.

What is midazolam?

Midazolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) that is used to sedate a person who is having a minor surgery, dental work, or other medical procedure.

Midazolam may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking midazolam?

You should not use midazolam if you are allergic to it, or if you have:

  • narrow-angle glaucoma;
  • untreated or uncontrolled open-angle glaucoma; or
  • an allergy to cherries.

Tell your doctor if you have ever had:

  • glaucoma;
  • breathing problems; or
  • congestive heart failure.

Tell your doctor if you are pregnant or breastfeeding.

How should I take midazolam?

Midazolam is usually given as a single dose just before your surgery or procedure.

Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication. Midazolam should be used only in a hospital, dentist office, or other clinic setting where any serious side effects can be quickly treated.

After you take midazolam, you will be watched closely to make sure the medicine is working and does not cause harmful side effects.


What happens if I miss a dose?


What happens if I overdose?


What should I avoid after taking midazolam?

Do not drink alcohol shortly after taking midazolam. This medicine can increase the effects of alcohol, which could be dangerous.

Grapefruit and grapefruit juice may interact with midazolam and lead to potentially dangerous effects. Avoid the use of grapefruit products for a short time after taking midazolam.

Midazolam can cause extreme drowsiness that may last for 24 to 48 hours after the injection. Older adults may feel sleepy for even longer.

Avoid driving or hazardous activity until the effects of midazolam have worn off completely. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

What are the possible side effects of midazolam?


Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing. Your caregivers will watch you for symptoms such as weak or shallow breathing.

Tell your caregivers right away if you have:

  • cough, wheezing, trouble breathing;
  • slow heart rate;
  • tremors; or
  • confusion, agitation, hallucinations, unusual thoughts or behavior.

The sedative effects of midazolam may last longer in older adults. You may need help getting out of bed for at least the first 8 hours. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury.

Common side effects may include:

  • amnesia or forgetfulness after your procedure;
  • drowsiness, dizziness;
  • nausea, vomiting; or
  • blurred vision.


What other drugs will affect midazolam?

Shortly after you are treated with midazolam, using other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.



Where can I get more information?

Your doctor or pharmacist can provide more information about midazolam.



Copyright 1996-2021 Cerner Multum, Inc. Version: 5.01. Revision date: 1/5/2021.
