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Incidence of liver disease in chronic lichen planus of the mouth.

Fifty-four patients with oral lichen planus were screened for chronic inflammatory liver disease utilizing standard biochemical parameters of liver function, serum levels of immunoglobulins G, A and M and circulating autoantibodies against mitochondriae, smooth muscle and cell nuclei. One patient had primary biliary cirrhosis, and another had cryptogenic cirrhosis. This study did not confirm previous observations of a frequent association of oral lichen planus and primary biliary cirrhosis or chronic active hepatitis.