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Practical considerations for territorial perfusion mapping in the cerebral circulation using super‐selective pseudo‐continuous arterial spin labeling

This paper discusses several challenges faced by super‐selective pseudo‐continuous arterial spin labeling, which is used to quantify territorial perfusion in the cerebral circulation. The effects of off‐resonance, pulsatility, vessel movement, and label rotation scheme are investigated, and methods to maximize labeling efficiency and overall image quality are evaluated. A strategy to calculate the territorial perfusion fractions of individual vessels is proposed.