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[Analysis of fatal cases of tuberculosis in the Arkhangelsk region in 2004].

Analysis of tuberculosis mortality in the civil sector of the Arkhangelsk Region in 2004 revealed that 55.4% of all death cases had been notified in patients with tuberculosis caused by multidrug-resistant Mycobacterium tuberculosis (MBT). In the above group of patients, 101 (85.6%) patients had not received chemotherapy with drug MBT resistance being kept in mind: tuberculosis autopsy was established in 15 patients with multidrug-resistance MBT at autopsy; in 5 patients MBT resistance to 7 and 8 antituberculosis agents had ruled out the use of etiotropic therapy; 81 patients had not received adequate treatment due to the shortage and spectrum of second-line antituberculosis drugs. The second cause of death from tuberculosis was the acutely progressive, disseminated forms of the disease, even, during treatment, leading to a fatal outcome, which were detectable in patients with a new case of tuberculosis (33.8% of all deaths) and its recurrence (5.6%).