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Photonic immobilization of high‐density protein arrays using Fourier optics

The technique of UV‐light‐assisted immobilization of disulfide containing proteins has been combined with the Fourier‐transforming properties of lenses as well as with a simple millimeter scale feature size spatial mask. The result is a new simple and inexpensive way of creating high‐density protein arrays with feature sizes down to a few hundred nanometers, which represents an improvement of tenfold over existing commercially available high‐density protein arraying methods.