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Development of small molecule fluorescent dye drug conjugates in targeted cancer therapy.

Since the beginning of the 20th-century use of chemical dyes opened the doors for cancer treatment with the development of Paul Ehrlich’s ground-braking concepts of chemotherapy and the magic bullet (Zauberkugel); an ideal therapeutic agent that would selectively kill only targeted pathological organisms without damaging the patient [1]. Now at the beginning of the 21st century, Dr. Leland W K Chung’s vision of developing a cancer magic bullet chemical dye has become a reality entering clinical trials.