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Therapeutic approach to the failing heart.

Currently recommended dosages for the more commonly prescribed drugs discussed above are given in Table 3. The approach to the failing heart in the pediatric patient requires an understanding of the pathophysiology of heart failure and an understanding of the mechanisms, effects and clinical pharmacology of several classes of therapeutic agents. The pediatric patient differs in many respects from his adult counterpart in the manifestations of heart failure and in his response to drug therapy to treat heart failure.