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A Case of Sporadic Eyelid Sebaceous Adenoma

Purpose: To report a case of sebaceous adenoma, which is a rare benign eyelid tumor.Case summary: A 45-year-old male presented with a visible mass on his left upper eyelid that had recurred 2 months ago. The mass had been resected 2 years ago. When the upper eyelid was everted, the tarsal portion of the mass was visible as a whitish papillary lesion. An incisional biopsy was done for pathological diagnosis and sebaceous adenoma was confirmed based on histopathological examinations. Subsequently, complete excision of the mass and eyelid reconstruction were performed under general anesthesia. Immunohistochemical studies were performed for differential diagnosis of Muir-Torre syndrome (MTS). Mutator L homologue 1, mutator S homologue 2, mutator S homologue 6 and PMS1 homolog 2 were all positive and he had no past medical or family history of internal malignancy, suggesting a very low possibility of MTS. Finally, the lesion was diagnosed as a sporadic sebaceous adenoma. The patient was followed up for 12 months without recurrence.Conclusions: Eyelid sebaceous adenoma should be considered as a differential diagnosis for an eyelid mass originating from the tarsal conjunctiva.