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Transfer therapy--Nevirapine for protease problems?


 A study by doctors in Spain found that people taking antiviral therapy may develop higher-than-normal levels of lipids and glucose in their blood, insulin resistance, and body shape changes due to fat redistribution. Switching to Nevirapine (Viramune) from a protease-based regimen reversed these side effects in 6 months, and levels of CD4+ and viral load remained unchanged in most subjects. Although lab measures were improved, body shape did not return completely to its pre-protease shape in any of the subjects.
