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Responding well to corticosteroid in an acitretin treatmentRelated acute lung injury patient with psoriasis

Acitretin is retinoic acid derivative that is approved for treatment of severe psoriasis. The side effect of retinoic therapy is all-trans retinoic acid syndrome. Here, we report a case of acitretin treatment associated acute lung injury in a psoriasis patient. Exhibited as a diffuse lung parenchymal injury, the differential diagnosis of infection, heart failure, and alveolar hemorrhage should be ruled out. A definite medication history is prerequisite for diagnosis of the disease. After correct diagnosis, the patient responded well to corticosteroid and the symptom and radiological changes of acitretin-induced acute lung injury alleviated soon.