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Genetic and sex influence on neuropathic pain‐like behaviour after spinal cord injury in the rat

Chronic pain of neuropathic nature after spinal cord injury (SCI) is common and its underlying mechanisms are poorly understood. Genes, as well as sex, have been implicated, but not thoroughly investigated in experimental genetic models for complex traits. We have previously found that inbred Dark‐Agouti (DA) rats develop more severe SCI pain‐like behaviour than a major histocompatibility complex‐congenic Piebald Virol Glaxo (PVG)‐RT1av1 strain in a model of photochemically induced SCI.