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Angiographic Diagnosis of Rejection and Tubular Necrosis in Human Kidney Allografts

Oliguria or anuria is not an infrequent complication of renal transplantation of cadaveric kidneys (CALNE et coll, 1963), the most common causes being immunologic rejection or ischemic tubular necrosis. Differentiation between these disparate states may be difficult on clinical grounds alone but can usually be accomplished by percutaneous biopsy (KINCAID-SMITH 1967). Not infrequently, however, the biopsy material may be insufficient to allow definite conclusions or may result in residual vascular abnormalities (SWEET et coll. 1969, EKELUND 1970) and untoward effects in a critically ill patient. When these limitations became apparent angiography was employed to aid in the diagnosis of these and other causes of functional failure of a renal graft.