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Innate immunity – a clinical perspective

During a few days in late September, 2018, the 15th Key Symposium was held in the beautiful setting of Exeter College in Oxford. The topic of the event was the innate immune system with a focus on a clinical perspective. More than 100 years have passed since Elie Metchnikoff in his work described phagocytosis, one of the key mechanisms in what he named natural immunity against invading pathogens [1]. This said, it should be noted that Elie Metchnikoff also invested significant research efforts in exploring the importance of microbiota, a subject of much research activity in recent years. During the symposium, highquality lectures were held, reflecting cutting-edge research in the area of innate immunity. In this issue of Journal of Internal Medicine, a number of reviews are published illustrating the rapid development.