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EFFECT OF CHRONIC UV EXPOSURE ON EPIDERMAL TRANSMISSION IN MICE *

In connection with an investigation on UV‐tumorigenesis in hairless mice, the question arose in what way the epidermal transmission changes under chronic UV exposure. At regular time intervals, epidermal sheets of these mice were optically probed, i.e. the specimen was irradiated perpendicularly to its surface with a collimated monochromatic beam of 313, 302 or 297 nm and the transmission was measured in forward direction and a small angle around it. The optical probe measurement was sensitive to epidermal changes and easy to perform; it correlated well with thickness and total transmission of the epidermal sheet.