{'fraction_non_alphanumeric': 0.05112474437627812, 'fraction_numerical': 0.02147239263803681, 'mean_word_length': 5.1572327044025155, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Differential effect of alpha-lactalbumin on beta-1,4-galactosyltransferase IV activities.

We isolated a human cDNA clone encoding beta-1,4-galactosyltransferase (beta-1,4-GalT IV) which shares 37% identity with previously characterized mammalian beta-1,4-GalT (beta-1,4-GalT I). By transfection of the full length cDNA into Sf-9 cells and assay of the cell homogenates, higher beta-1,4-GalT activity toward GlcNAc beta-S-pNP was obtained, and its activity was modulated with alpha-lactalbumin, while no lactose synthetase activity was detected in the presence of alpha-lactalbumin. Northern blot analysis using total and poly (A)+ RNA preparations revealed that the expression level of beta-1,4-GalT IV transcript is low and relatively constant while that of beta-1,4-GalT I transcript is dramatically increased in the mouse mammary gland during lactation. These results indicate that beta-1,4-GalT IV can interact with alpha-lactalbumin but has no lactose synthetase activity.