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Expression profiles and functional associations of endogenous androgen receptor and caveolin‐1 in prostate cancer cell lines

In prostate cancer (PCa) patients, the protein target for androgen deprivation and blockade therapies is androgen receptor (AR). AR interacts with many proteins that function to either co‐activate or co‐repress its activity. Caveolin‐1 (Cav‐1) is not found in normal prostatic epithelium, but is found in PCa, and may be an AR co‐regulator protein.