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Optically induced concomitant strabismus in monkeys.

In infant monkeys that view the world through dissociating prisms the binocular neurons of the striate cortex cease to function. The loss of binocular cortical neurons is proportional to the duration of prism wear. Virtually all binocular neurons will disappear from the striate cortex within 60 days, and the remaining monocular neurons will become equally divided, between the two eyes. Although the cortical neuron population is dramatically altered, this form of experimental strabismus failed to affect the size of principal cells of the lateral geniculate nucleus.