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NEONATAL MORTALITY IN INFANTS RECEIVING AN EXCHANGE TRANSFUSION

Over an 18‐year period, 1,830 exchange transfusions were performed on 1,160 infants born at the Royal Women's Hospital, Melbourne with a total mortality of 9.8% for infants with Rhesus incompatibility contrasted with 3.3% in patients with other causes for hyperbilirubinaemia. The 6‐hour procedure mortalities were 3.5% and 0.6% respectively. Although deaths due to the technique of transfusion decreased over the review period, the overall mortality of infants with Rhesus incompatibility did not decline because premature induction of labour resulted in increasing numbers of very small infants. The mortality was highest when severe anaemia and respiratory distress co‐existed.