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Investigation of Brain Anatomy in Individuals with Trisomy 21 versus Euploid Controls

Having three copies of human chromosome 21, also known as Down syndrome (DS), results in gene dosage imbalances causing changes in brain morphology. There are few studies focused on how DS affects brain morphology in young children, as most are focused on adults who exhibit an Alzheimer's‐like dementia. Therefore, our project aims to fill this gap in the current knowledge of DS in children.