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Prognostic factors in gastric cancer evaluated by using Cox regression model.

OBJECTIVE
To identify the most relevant short-term predictor variables in gastric cancer removal.


EXPERIMENTAL DESIGN
A retrospective survival analysis executed by using the Cox regression model; the follow-up period is included between 18 and 90 months.


SETTING
A district general hospital surgery unit: "Divisione di Chirurgia Generale, Ospedale Civile di Urbino" (Marche, Italy).


SUBJECTS
One hundred and twenty nine consecutive patients operated for gastric cancer.


INTERVENTIONS
Surgery (total or subtotal gastrectomy).


MAIN OUTCOME MEASURE
Survival times.


RESULTS
Lymph node involvement (N) (p < 0.0001), cancer intraparietal extension (T) (p < 0.001) and the age of the patients (p < 0.05) have been recognized as significant prognostic factors.


CONCLUSIONS
Results show that the short-term prognosis largely depends on both the earliness of the diagnosis and the age of the patients.