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Initial Steps in Developing Genetic Markers to Predict/Recommend Weight Management Products

It has been estimated that the U.S market for weight loss products will increase 1.7% over the next 16 months to an annual sales level exceeding $61 billion dollars1. The consumer market is overwhelmed with products aimed to help people manage their overall weight. An overall public health goal is to develop a lab test or series of lab tests to support the use of consumer weight management products to predict/recommend the correct regimen for an individual, monitor the treatment progress and to understand the molecular‐level interactions between diet, lifestyle and the genome. MicroRNAs are small, non‐coding RNA molecules that function as negative regulators of gene expression. A growing number of studies have described the use of microRNA biomarkers in nutrition.