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[Study on anticholinergics for the treatment of high altitude pulmonary edema].

OBJECTIVE
To evaluate the clinical effects and mechanism of anticholinergics in treating high altitude pulmonary edema (HAPE).


METHODS
582 patients with HAPE (in 4700-5260 m) were divided into 2 groups: one group (393 patients) was treated with anticholinergic (Group A), and the other 189 cases were treated with a general therapy without anticholinergic (Grorp B).


RESULTS
Compared with Group B, the average admitted days were reduced, the symptom, physical and X-ray signs disappeared more quickly (P < 0.001), the cure rate was raised clearly (P < 0.05) in Group A and the abnormal changes of hemodynamics had been adjusted (P < 0.05, P < 0.01).


CONCLUSIONS
Anticholinergic used for HAPE has a rapid and exact curative effect, a slight side effect, and a shorten course of treatment.