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Seventh TRM Forum on Computer Simulation and Experimental Assessment of Cardiac Function: creating the basis for tailored therapies.

Computer simulations have gained increasing importance for the understanding of cardiac arrhythmias and the development of new therapeutic solutions, overcoming some of the limitations encountered in clinical and experimental research. Progresses in computer models depend on continuous exchange of clinical and experimental data, both for model development and validation. Therefore, it is important that experts from these two fields communicate.

Today, patient-specific models based on clinical imaging and electrophysiological data are becoming a reality. Such models could be used in the future for guiding individual clinical antiarrhythmic therapies. The challenge lies in how to translate these computer methods into clinically effective tools. To that end, since 1998 the Theo Rossi di Montelera (TRM) forum has brought together researchers with different expertise in computer modelling, experimental and clinical research. The seventh TRM forum was held in Lugano, Switzerland, on 1–3 December 2013, hosted by the Lausanne Heart group, the University of Lugano (USI) and the Cardiocentro Ticino (CCT). The theme was ‘Creating the Basis for Tailored Therapies’.

The objective of the TRM forum is to facilitate the translation of basic science findings in computer modelling into the clinical field. The first day of the forum was therefore focused on ‘From computer to bedside: how predictive are computer models’ with the presentation of latest patient-specific computer models of the atria and ventricles and how they can be used to predict the effect of cardiac therapies. The second day followed the opposite pathway ‘From bedside …