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Industry Viewpoint of Clinical Trials

Everyone whose career in science spans more than a few years is bourid to witness and hopefully participate in the evolution of his discipline. Occasionally that evolution progresses quickly. At other times it proceeds with imperceptible slowness. Sometimes it is accelerated by environmental circumstances and pressures, sometimes it is retarded by them. As with other disciplines, clinical research has.evolved during the past two decades and the pharmaceutical industry has been an important part of that process. That evolution has been triggered by a number of factors which have become inextricably linked with one another. Firstly, the medical profession, in part due to its increasing sophistication about medicines, has demanded more scientific information. Secondly, pharmaceutical companies have responded to these demands and have superimposed additional demands of their own for clinical information which can guide the future studies of basic research workers. Thirdly, regulatory authorities have set standards and mandated compliance with them. The end result has been an explosion of information about new medicines and a rapid development of the science of clinical research. With this has come a change in the role of the pharmaceutical physician. In past times his function was almost exclusively in