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Prostate cancer management.

The management of prostate cancer poses both dilemmas and opportunities. A sensitive tumour marker provides the opportunity for early diagnosis, yet for many patients, the benefit of early treatment is uncertain. It is a tumour that is exquisitely sensitive to hormonal manoeuvres, but the benefits of cytotoxic chemotherapy is less apparent for the majority of patients. This brief review will comment on elements of natural history, staging investigations, prognostic factors, early disease presentations, hormone therapy in advanced disease and management issues in hormone refractory prostate cancers.