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Epilepsy and cardiac surgery.

The complex and sometimes severe metabolic, haemodynamic or blood modifications induced by cardio-pulmonary bypass (CPB), can result in alteration of cerebral electrogenesis and even in epileptic paroxyms. Nineteen epileptics (EP) and 41 risk patients (PR), 31 with a family history of epilepsy (FHE) and 10 prone to epilepsy (PPE) were operated upon under CPB; 6 of the EP and 2 of the PPE had abnormal but no paroxymal EEG features during operation. None of the other EP or PR showed any epileptic abnormalities. It seems that normothermia, light haemodilution and elimination of neuroleptic drugs for analgesia prevent per and post-operative epileptic paroxysms.