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Genetics and Genomics in Medicine

1. Fundamentals of DNA, Chromosomes, and Cells 2. Fundamentals of Gene Structure, Gene Expression, and Human Genome Organization 3. Principles Underlying Core DNA Technologies 4. Principles of Genetic Variation 5. Single-gene Disorders: Inheritance Patterns, Phenotype Variability, and Allele Frequencies 6. Principles of Gene Regulation and Epigenetics 7. Genetic Variation Producing Disease-Causing Abnormalities in DNA and Chromosomes 8. Identifying Disease Genes and Genetic Susceptibility to Complex Disease 9. Genetic Approaches to Treating Disease 10. Cancer Genetics and Genomics 11. Genetic Testing From Genes to Genomes, and the Ethics of Genetic Testing and Therapy