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A Complex Ph1 Translocation in a Patient with Primary Thrombocythaemia

Summary. Routine blood examination of a 27‐year‐old female revealed a platelet count of 2000 109/1. Bone marrow cells showed the Philadelphia chromosome which was one product of a complex rearrangement of chromosomes 9, 22 and X. Her platelet count was lowered by plateletphoresis and chemotherapy. She remains in good health 19 months later, but her thrombocythaemia is considered to be an early manifestation of chronic myeloid leukaemia.