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MOST STROKE PATIENTS DO NOT GET A WARNING: A POPULATION-BASED COHORT STUDY

In longitudinal studies with active outcome surveillance, the 3-month risk of stroke after TIA is approximately 17%.1 Recent reports suggest that expedient management of TIA can reduce this risk by as much as 80%.2,3 For such a strategy to have a major impact on the burden of cerebrovascular disease in the general population, stroke with preceding TIA must be a relatively common occurrence. Using data from the Registry of the Canadian Stroke Network (RCSN), we sought to ascertain the frequency, characteristics, and outcomes of acute stroke patients with a prior TIA.

### Methods.

We prospectively identified consecutive patients with a final diagnosis of acute stroke admitted to 12 Ontario hospitals through data recorded in the RCSN (accrual interval July 1, 2003, to September 30, 2007). Chart validation studies have shown excellent agreement with the RCSN database, with duplicate data abstraction performed on a random sample of 10% of charts. Patients with in-hospital strokes (n = 78) or unknown final diagnosis (n = 615) were excluded. Further details regarding the RCSN have been published …