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papA Gene of Avian Pathogenic Escherichia coli

Important Findings Researchers analyzed the pyelonephritis-associated pilus (pap) or P fimbrial operon, specifically the papA gene that encodes the major fimbrial shaft, to better understand the pap gene cluster at the genetic level. Study results showed it is likely that transposons bearing antibiotic resistance genes have inserted within the pap gene cluster of some avian pathogenic Escherichia coli (APEC) strains, and such genetic events may have been selected for by antibiotic use.