{'fraction_non_alphanumeric': 0.023537323470073975, 'fraction_numerical': 0.019502353732347006, 'mean_word_length': 5.386266094420601, 'pattern_counts': {'":': 0, '<': 2, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
INTRATHECAL MORPHINE TO CONTROL PAIN AFTER REMIFENTANIL BASED ANESTHESIA IN MAJOR ABDOMINAL - PELVIC SURGERY

Objective: The purpose of this study was to evaluate the efficacy of post-operative analgesia with 200 μg intrathecal morphine after intraoperative administration of remifentanil. Patients and methods: Eighty patients scheduled for open abdominal-pelvic surgery were included in this prospective randomized simple blind study. After 200 μg intrathecal morphine administration before induction, patients were randomized to receive either remifentanil or fentanyl with propofol and cistatracurium for induction and per-operative management. Vital signs, emergence profiles were assessed and recorded. Results: Remifentanil provided more haemodynamic stability than fentanyl during peroperative management. The mean times to recorvery and extubation were also shorter with remifentanil: 7 min versus 11 min for e x tubation ( p<0.05). The mean time for first need of paracetamol for post-operative analgesia was shorter in the remifentanil group: 49 min versus 68 min, (p =0 .56). Total consumption of paracetamol during the first 24 postoperative hours was the same in the two groups. There was no need for postoperative intravenous morphine administration. There was no case of respiratory depression in the postoperative period and the mean lentgh of time before discharge from the recorvery room was 26 min in the remifentanil group and 129 min in the fentanyl group (p<0,05).