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Serum 25(OH)D does not correlate with BMI or cardiovascular fitness in young adults with sufficient vitamin D status

Vitamin D supplementation is an emerging approach for enhancement of physical performance. Correlations have been found between low vitamin D status (circulating concentration of 25(OH)D) and cardiorespiratory fitness (CRF), however the evidence supporting the ergogenic effect of vitamin D in subjects with sufficient status of this vitamin is lacking. The purpose of this study was to investigate the relationship between serum 25(OH)D, CRF and body mass index (BMI) in young adults. Twenty physically active (4.1±3.4 h/wk, VO2peak=48.9±6.9 mL·kg−1·min−1), normal weight (BMI=22.9±2.2), college age (21.5±2.1) men and women participated in the study. Serum samples were analyzed for 25(OH)D using chemiluminescent EIA (Diazyme 25‐OH Vitamin D Assay). A two‐way ANOVA with interactions was used to compare differences between variables. The results showed that serum 25(OH)D concentration (25.7±6.0 ng/mL) had no correlation with VO2peak (p=0.510) or BMI (p=0.889) in men or women. All but one of the subjects had a 25(OH)D concentration >;20 ng/mL, and 5 subjects had 25(OH)D level >;30 ng/mL. The findings obtained indicated that serum levels of 25(OH)D, which are generally considered as sufficient, were not correlated with BMI or CRF in healthy, college‐aged men and women. Supported by NIH grant 8P20GM103443–12.