{'fraction_non_alphanumeric': 0.0267515923566879, 'fraction_numerical': 0.005095541401273885, 'mean_word_length': 5.442622950819672, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Photoarylation of Pyridines using Aryldiazonium Salts and Visible Light: An EDA Approach.

A metal-free methodology for the photoarylation of pyridines, in water, is described giving 2 and 4-arylated-pyridines in yields up to 96%. The scope of the aryldiazonium salts is presented showing important results depending on the nature and position of the substituent group in the diazonium salt, i.e., electron-donating or electron-withdrawing in the ortho, meta or para positions. Further heteroaromatics were also successfully photoarylated. Mechanistic studies and comparison between our methodology and similar metal-catalyzed procedures are presented, suggesting the occurrence of a visible light EDA complex which generates the aryl radical with no need for additional photocatalyst.