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An Automated Flow Microfluorometer and Cell Sorter Incorporating Nuclear Electronics

A computer-automated flow microfluorometer and cell sorter is under development for the Medical Department of Brookhaven National Laboratory. The device will be capable of analyzing and sorting samples of biological cells based on measurements of laser-induced fluorescence and cell volume. The system incorporates the laser optics and droplet generation mechanics of a standard Becton-Dickinson FACS II cell sorter. The capabilities of the FACS II device are being upgraded, chiefly in the areas of data display and recording and, to a lesser extent, on-line data analysis.