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Development and harmonisation of the norms and parameters in biological testing protocols designed for root canal sealing materials within the European Community.

The EC has mounted the BIOMED 1 as a specific programme to facilitate cooperative research programmes in identified areas of interest throughout Europe. They have recently announced support under this programme for a joint initiative designed to evaluate in vitro and in vivo methods of biological testing of root canal sealing materials. This proposal was prepared by a group of research workers in the field. It provides a summary of the current suggested protocols for the biological testing of dental materials and then provides a detailed protocol of the studies to be carried out in the joint programme which commenced in January 1993. The authors are publishing the proposal to invite comments from colleagues and interested parties.