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The interplay between dendritic cell subsets and T cells during peripheral virus infection

Dendritic cells are a heterogenous population consisting of a number of distinct subsets. It is likely that this heterogeneity reflects functional differences between the populations. We have been exploring the role of dendritic cells during infection with herpes simplex virus (HSV) ‐ starting with the initial virus infection in the skin through to the reactivation of HSV within the nerves. I will present results of experiments examining how different dendritic cell subsets are called into play during the separate phases of infection with this virus.