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Self-reported personality disorders in patients with schizophrenia and the relationship to symptoms, side effects and social functioning

In a national, naturalistic, point prevalence, multicenter study, patients with schizophrenic syndromes were studied with regard to self-reported personality disorders, symptoms, side effects, and social functioning. Ninety-one of 116 patients with a schizophrenic syndrome responded to the DSM-IV and the ICD-10 Personality Questionnaire (DIP-Q). In total, 43 of the patients (47%) fulfilled the criteria for one or more personality disorders. The most common personality disorders found were in cluster C and in cluster A? 44% and 34%, respectively. Comorbidity between and within clusters was high. Personality-disordered patients displayed significantly more negative, anxious:depressive, and cognitive symptoms than patients without personality disorders. Sex, age, duration of illness, and extrapyramidal side effects on the basis of the Extrapyramidal Side effect Rating Scale (ESRS) did not differ between the groups. However, psychic side effects, measured with the UKU (Utvalg for Kliniske Undersøkelser) Side Effect Rating Scale were significantly more common in the group of patients with self-reported personality disorders. Social functioning rated by a modified version of the Strauss ? Carpenter rating scale and the Global Assessment of Functioning scale (GAF) did not differ between the groups.