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Optical transillumination spectroscopy of breast tissue for assessment of cancer risk

Breast cancer is the most commonly occurring cancer in women and the lifetime risk (at age 85) of being diagnosed is approximately 1 in 10 [1], the highest probability out of all cancers. Breast cancer screening programs have been shown to decrease the mortality rates of women age 50-69 [2] due to detecting cancer at an earlier, treatable stage, however compliance is low due to a variety of reasons. While the understanding of the underlying causes and mechanisms leading to breast cancer is increasing, development of the disease is not fully understood. Hence, there has been a push to propose, develop and understand risk factors for the disease; which are defined as those characteristics that people with the disease have in common [3].