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Defining Antibiotic Inertia: Application of a Focused Clinical Scenario Survey to Illuminate A New Target for Antimicrobial Stewardship During Transitions of Care.

In clinical scenario surveys, inpatient providers were more likely to continue inappropriate antibiotic therapy (OR 2.02; 95% CI 1.35-3.03, p<0.001) or broad therapy (OR 1.8; 95%CI 1.27-2.56, p=0.001) when initiated by ED providers, as compared to appropriate or narrow antibiotics, respectively. Antibiotic inertia could represent a significant antibiotic stewardship target.