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[Imipenem/cilastatin sodium in the treatment of obstetric and gynecologic infections].

Imipenem/cilastatin sodium (MK-0787/MK-0791), a carbapenem antibiotic and a dehydropeptidase-I inhibitor, was administered at a dose of 500 mg/500 mg twice a day for 5 days for the treatment of obstetric and gynecologic infections. A total of 10 patients was evaluated, and the clinical results were rated as excellent in 1, good in 7 and poor in 2 patients. As a side effect, rash was observed in 1 patient but it disappeared by the third day after the treatment was discontinued. No abnormal laboratory findings were observed in our study.