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Corlanor (Ivabradine), First HCN Channel Blocker, FDA Approved for the Treatment of Patients with Heart Failure.

Heart failure is a life-threatening condition that affects approximately 5.7 million individuals aged ≥20 years in the United States.1 With an estimated 870,000 new cases of heart failure occurring annually, heart failure is expected to affect more than 8 million people aged ≥18 years by 2030—an alarming 46% increase from 2012.1 And because heart failure increases in individuals aged ≥65 years, this disease will have a major impact in the coming decades as the aging US population increases steadily.1