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[Effects of bovine plasma fibronectin on the proliferation of rat osteoblast in vitro].

OBJECTIVE
To investigate the effects of bovine plasma fibronectin on the proliferation of rat osteoblast in vitro.


METHODS
Cell cultured. AlamarBlue were used to determine the effect of various concentration of bovine plasma fibronectin on the proliferation of rat osteoblast in vitro.


RESULTS
Fibronectin can stimulate the proliferation of rat osteoblasts. Statistically significant difference was detected at dose of 40 micrograms/ml (P < 0.05) and dose of 50 micrograms/ml (P < 0.01).


CONCLUSIONS
Certain concentration of bovine plasma fibronectin can stimulate the proliferation of rat osteoblast in vitro.