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Serrated Polyps of the Large Intestine: A Practical Approach

An understanding of the pathology, molecular biology, and natural history of serrated polyps of the large bowel has emerged comparatively recently. In this review, the authors discuss sessile serrated adenoma and the term sessile serrated polyp and how to differentiate these lesions from hyperplastic polyps, and traditional serrated adenoma. Hyperplastic polyps, sessile serrated adenoma, and traditional serrated adenoma are conceived as a continuum of serrated polyps. Molecular biology of the “serrated pathway” is briefly discussed. Suggested reporting and management are outlined.