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The relative importance of cardiovascular risk factors in type 2 diabetes

Coronary artery disease (CAD) is the cause of death of many patients with type 2 diabetes (T2D). Type 2 diabetes intensifies the risk associated with cardiovascular events, especially coronary heart disease. Major risk factors for CAD in patients with T2D are dyslipidaemia (high low‐density lipoprotein cholesterol, low high‐density lipoprotein cholesterol, high total triglycerides), elevated blood pressure, smoking, hyperglycaemia, and insulin resistance. Treating these conditions (dyslipidaemia, elevated blood pressure, and hyperglycaemia) as single cardiovascular risk factors is beneficial, but multifactorial intervention may be more clinically beneficial in preventing cardiovascular complications or secondary cardiovascular events.