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Association of Leptin With Disease Severity and Inflammation Indicators in Chinese Obese Children With Allergic Rhinitis

W Liu, Q Zeng, L Zhou, R Luo, H Dong. Pediatr Allergy Immunol. 2018;29(2):186–193

To examine the effect of obesity on the prevalence and severity of allergic rhinitis (AR) as well as examine possible contributing key inflammatory mediators.

The study included 3126 randomly selected healthy Chinese students (ages 7–12 years). Overall, there were 578 children with AR and 2548 children in the control group.

Obesity was defined as a BMI greater than the local age- and gender-specific …