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Elevated serum S‐100β in patients with septic shock is associated with delirium

A high prevalence of delirium is observed in sepsis, yet specific markers for this brain dysfunction in sedated patients are still lacking. Cytoplasmic low molecular weight calcium‐binding protein, S‐100β, is a commonly used nonspecific marker for brain injury. Here, we evaluated whether delirium is associated with increases in S‐100β levels.