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A comparative study between trabeculotomy with deroofing of Schlemm′s canal augmented with Ologen implant and conventional trabeculotomy in primary congenital glaucoma

Purpose The aim of the study was to evaluate the efficacy and safety of Schlemm′s canal deroofing augmented by Ologen to enhance the success of trabeculotomy for primary congenital glaucoma (PCG). Patients and methods Thirty-two eyes of 21 patients were included in this prospective study, classified into two equal groups: the study group and the control group. The study group underwent trabeculotomy with Schlemm′s canal deroofing and subconjunctival Ologen implantation, and the control group underwent trabeculotomy alone for infants affected by PCG. The participants were followed up for 6 months. Results According to the definitions for success, qualified success, and failure, the study group had 13/16 (81.25%) cases of success and 3/16 (18.75%) cases of qualified success. The control group reported 10/16 cases (62.50%) of success, 2/16 cases (12.50%) of qualified success, and 4/16 cases (25%) of failure. Conclusion Success and qualified success were higher in the study group (trabeculotomy augmented with deroofing of Schlemm′s canal and Ologen implant) than in the control group after 6 months of follow-up for cases of PCG.