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MRI fusion biopsy vs transrectal ultrasound guided biopsy -A literature review

Introduction: Current diagnosis of prostate cancer is based on transrectal ultrasound guided random biopsies. These procedures alongside with the discovery of PSA lead to a tremendous improvement of prostate cancer diagnosis rate in the last decades. Random ultrasound guided biopsy has its minuses and several attempts were made to improve the detection rate of the disease. MRI-US fusion targeted biopsies is one of them. Aim: This paper is a literature review of several important European studies and tries to draw a conclusion for the usefulness of MRI-US image fusion prostate biopsy in improving prostate cancer detection Material and methods: We have analyzed 5 papers published since 2013 which compare random ultrasound biopsies with MRI-US fusion. The analyzed parameters were clinical significant cancer detected as described by the study and any cancer detected Results: All 5 papers show superiority in cancer detection rates for both clinically significant and any cancer. Conclusions: MRI-US is a useful tool for improving detection rate of clinically significant prostate cancer.