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Comparison of Bayesian‐derived and first‐order analytic equations for calculation of vancomycin area under the curve

Consensus guidelines recommend targeting a vancomycin area under the curve to minimum inhibitory concentration (AUC24:MIC) ratio of 400–600 to improve therapeutic success and reduce nephrotoxicity. Although guidelines specify either Bayesian software or first‐order equations may be used to estimate AUC24, there are currently no large studies directly comparing these methods.