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Allergic contact dermatitis of the face from contact with nickel and ammoniated mercury in spectacle frames and skin‐ lightening creams

A total of 507 (M 121, F 386) cases of facial dermatitis were investigated, of whom 308 (m 49, F 259) had eczema confined to the face. The prevalence of positive patch tests was 45% (229/507). Among all the patients, the 2 most frequent allergens were nickel (15.2%) and ammoniated mercury (6.1%), with the incidence of nickel sensitivity in men (20%) being greater than in women (13.7%) 56% of the nickel‐positive cases were caused by metal spectacle frames. Taiwan's high number of spectacle‐wearers, its subtropical climate and the characteristic oriental facial structure are possibly major contributing factors. Most ammoniated mercury (AM) sensitive cases resulted from cosmetics. Skin‐lightening creams are widely used in Taiwan, but their content is poorly controlled. According to consumer reports, 14.9% (48/322) had applied AM‐containing cosmetics, of all the cosmetics tested for mercury, 2.2% (60/2711) were positive.