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In vivo effects of insulin on tumor and skeletal muscle glucose metabolism in patients with lymphoma

Background. The anabolic properties of insulin have been suggested for use to reverse malnutrition associated with cancer. The host and tumor sensitivities to insulin are critical for such treatments, which aim to improve patient nutrition. The authors studied insulin effects on tumor and skeletal muscle metabolism with 2‐[18F]‐fluoro‐2‐deoxy‐D‐glucose ([18F]FDG) and positron emission tomography (PET).