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Lack of relationship of community patterns of respiratory viral activity to systemic Haemophilus influenzae disease in children

The occurrence of epidemics of respiratory viral illness was monitored by virus isolations in a population of young children living in the greater Nashville area over a 4-year period. Epidemic disease due to influenza, respiratory syncytial virus and parainfluenza type 1 was present during discrete time blocks over this interval. Occurrence of systemic Haemophilus influenzae type b disease in the community was also documented by review of bacteriologic records of Vanderbilt Children's Hospital over the same interval. No correlation of the occurrences of epidemic viral disease and systemic H. influenzae type b disease was evident by this comparison.