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The value of roentgenography in differentiating aplastic anemia from leukemia masquerading as aplastic anemia.

Three cases of leukemia originally diagnosed by peripheral blood and bone marrow studies as aplastic anemia are reported.They had roentgenographic skeletal lesions, nonspecific of, but compatible with leukemia when initially seen. One patient also had enlarged kidneys with distorted calyceal anatomy from leukemia infiltrates. Fifteen true aplastic anemia patients had normal skeletal series.A roentgen survey of the skeleton and kidneys may be of value in differentiating true aplastic anemia from the aplastic phase of leukemia.The optimal site for skeletal biopsy can also be determined.