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Antimicrobial potential and phytochemical screening of different extracts of Rumex dentatus and Saussurea lappa from Kashmir Himalaya, India

In the present study, antimicrobial and phytochemical activities of the two important medicinal plants Viz. Rumex dentatus, Saussurea lappa was carried out with the help of Agar well diffusion method. The pharmacological activity of Rumex dentatus, Saussurea lappa against Escherichia coli, Bacillus amyloliquefaciens, Pseudomonas aeruginosa, Staphylococcus aureus was tested. It was recorded in our study that aqueous extract has shown the significant antibacterial activity in all the plant extracts against all the tested bacterial strains. Aqueous extract of Rumex dentatus was found to be very effective against Pseudomonas aeruginosa (35 ± 0.44 mm) whereas aqueous extract of Saussurea lappa has been recorded with highly effective against Bacillus amyloliquefaciens (31± 0.44 mm). Further, ethanol, methanol, and aqueous extract of Saussurea lappa have shown the promising antibacterial activity against Bacillus amyloliquefaciens, Pseudomonas aeruginosa, Staphylococcus aureus except in case of methanol against Escherichia coli. Further, methanol extract of Rumex dentatus has shown great antimicrobial activity that other. Methanolic extract of Rumex dentatus extracts inhibited none of the tested bacterial strains in our study. The phytochemical investigation of the various extract of Saussurea lappa showed a positive result for Saponin, Tanin, and Phenol in methanol and ethanol extract. Terpenoid, Carbohydrate, and phenol were tested positive in all the solvents for Rumex dentatus and Saussurea lappa whereas steroid, Phlobatannin, Starch, Flavonoid, Napthoquione, and Insulin were absent in all the extract of Rumex dentatus and Saussurea lappa. We can conclude from the study that Rumex dentatus and Saussurea lappa can be used as a potential source of treating different diseases due to their great antimicrobial and biological activity along with various phytoconstituents.