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Potential use of male antifertility agents in developed countries.

This paper summarizes the potential use of male antifertility agents in developed countries. Agents should be efficacious relatively safe self-administered devoid of adverse effects inexpensive and reversible. Potential use will be influenced by the mode of action of the drugs particularly those that inhibit male fertility in a rapid fashion and those that render epididymal spermatozoa infertile. Most surveys indicate that men wish to be involved in family planning. Large numbers of vasectomies attest to the fact that a sizeable number of men are willing to accept this quasi-irreversible approach. Male fertility regulation by drugs is acceptable in developed countries if the drug is proved to be highly effective. Acceptibility of male contraceptive methods varies according to race culture education and economic status. Future acceptability of male contraceptive drugs is dependent on their advertised effectiveness. Private industry surveys indicate that a market for male drugs exists and that the costs of developing the industry are high.