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Cigarette smoking, blood pressure and serum lipids in Japanese men aged 20-39 years.

Adverse effects of cigarette smoking on serum or plasma lipids have been reported in a metaanalysis (Craig et al., 1989). The relationship between cigarette smoking and blood pressure (BP) has also been reported by Green et al. (1986) who examined the results of 15 published studies and pointed out that negative associations between cigarette smoking and BP were consistently noted across several cross-sectional epidemiological studies. However, many of the published data are based on middle-aged individuals. Only few data exists for young subjects. The smoking rate in Japan is the highest in young men (60.9%) aged 20 to 29 years and declines with increasing age (The Ministry of Health and Welfare, 1998). In a previous study from our laboratory (Imamura et al., 1996), we have reported that there was a dosedependent negative relationship between cigarette smoking and diastolic BP (DBP) and high-density lipoprotein cholesterol (HDL-C) in middle-aged men, independent of drinking habit. The purpose of this study was to examine the relationship between cigarette smoking and BP and serum lipids in Japanese men aged 20 to 39 years, taking into account several potential confounding factors such as age, body mass index (BMI) , alcohol intake and physical activity habits.