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Pleural effusion associated with urinary tract obstruction: support for a hypothesis.

Pleural effusions associated with urinary tract obstruction (urinothorax) appear to be unusual, only eight cases having been reported since the first description by Corriere and his colleagues in 1968.1 The patient described here developed a pleural effusion associated with spontaneous perinephric extravasation of urine secondary to ureteral obstruction. However, the differing chemical composition of these fluids indicates that direct extension of urine into the pleural space, as previously suggested, had not occurred, and we propose that pleural effusions associated with urinary tract obstruction develop by another mechanism.