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[Effect of age factor on the structure of the wall of the esophagus.]

The structure and cytoarchitecture of the structures of the wall of the esophagus was studied by histological and morphometric methods. We investigated the upper, middle and lower third of the esophagus in people 1 and 2 of the mature, elderly and senile age. It was established that in old age comes the destruction of the epithelial lining, the muscular propria of the mucous membrane. The number of lymphocytes, neutrophilic leukocytes and eosinophils in the epithelium increases by 2-3 times. The content of cells of the fibroblastic and lymphoid series increases in lamina propria and glands. Infiltrates appear in the mucous membrane, microerosions appear. Particularly vulnerable areas are the papillas of lamina propria. In the places of their location the most frequent accumulations of lymphocytes are noted. Among mast cells, the processes of degranulation increase, the number of mast cells with a small amount of granules increases. Inflammation is often found in the lower sections. Age-related changes in the wall of the esophagus depend on the individual characteristics of a person.