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Humoral and cellular indices of immunity in newborns with early realization of the allergically changed reactivity

The complex immunologic examination in 39 children aged 2 to 28 days with early realization of the allergically changed reactivity in boys 61,5%, in girls 38,5% is performed. The peculiarities of immunologic reactivity in children with early realization of the allergically changed reactivity (the increase of the immune regulatory index due to the deficiency of CD 8+ lymphocytes, the increased expression of activation markers, the increase of Ig E) show the prevalence of the atopic response type. Uniformity of changes of the immune status indices in early and late neonatal period testifies the intrauterine and/or early change of immunocompetent cell phenotype under the influence of perinatal development factors of a child