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Application of Porous Chitosan/Gelatin Bone Scaffolds Used in Bone Tissue Engineering

Chitosan (CS) and gelatin (G) both have good biocompatibility and biodegradation, qualifying them for use in tissue engineering. In this study, CS and G are blended with different ratios to make the mixture solution, and then freeze-dried to form three-dimensional porous CS/G bone scaffolds. The surface, cross-section, porosity, and pore size of the resulting bone scaffolds are observed and analyzed. According to the experimental results, the addition of gelatin gives the CS/G bone scaffolds morphology with few pores. As can be seen from SEM observation, there are linear pores in the cross-section. In addition, with a larger quantity of gelatin, the CS/G bone scaffolds have a lower porosity.