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Application of DNA walker in biosensing and living cell imaging

: DNA walkers are a type of self-assembled nanodevices based on the specificity, predictability and programmability of DNA hybridization. The walking components can move autonomously and gradually along the predetermined track under specific external stimuli. These features of autonomous movement and repetitive stepping endow them with excellent signal amplification capability, making the DNA walker show a good application prospect in chemical measurement. This article systematically reviewed the research progress of the DNA walker in the fields of biosensing and living cell imaging.