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The effects of airway occlusion after oxygen breathing on the lungs of newborn infants. Radiologic demonstration in the experimental animal.

Abnormal ventilatory patterns and mechanical obstruction of airways are common problems in infants with respiratory failure. Chest radiographs are often requested after ventilation with 80 to 100% oxygen. Previous experiments have shown that bronchial occlusion after breathing pure oxygen results in gas-freeing of an obstructed lobe. Rapid complete pulmonary opacification on radiographs has been observed in some infants and it is suspected that this is due to rapid oxygen resorption during respiratory arrest. This was demonstrated in a puppy following oxygen breathing for 25 to 50 minutes through an endotracheal tube. Occlusion of the tube resulted in complete gas-freeing of the lungs in 3 to 5 minutes.