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Effect of Chemical Fixation on the Fiber Kinematics of Bovine Pericardium


 Microstructural modeling of chemically treated bovine pericardium (BP), a popular material for cardiovascular bioprostheses, requires knowledge of the initial collagen fiber angular distribution and fiber kinematics.1 In a previous study, utilizing combined small angle light scattering (SALS) and biaxial stretch, we found that the collagen fibers in fresh BP reorient towards the direction of stretch to a greater extent than predicted by an affine transformation model.2