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Eosinophilic fasciitis associated with L-tryptophan ingestion.

OBJECTIVE
To present the first case of eosinophilic fasciitis associated with L-tryptophan ingestion.


CLINICAL FEATURES
A 23-year-old Australian man developed myalgia and weakness, and later the clinical features of eosinophilic fasciitis, while taking L-tryptophan.


INTERVENTION AND OUTCOME
The amino acid supplementation was discontinued and he was treated with prednisone (30 mg/day) for six weeks with significant improvement.


CONCLUSION
In sclerodermatous skin diseases, such as eosinophilic fasciitis, the possibility of ingestion of tryptophan-containing products should be considered.