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Papular Lesion on the Knee of a 7-Year-Old Girl.

HISTOPATHOLOGICAL FINDINGS The epidermis was slightly atrophic with compact hyperkeratosis and showed peripheral scaling collarette bilaterally. There was a circumscribed symmetrical lesion in the dermis composed of aggregates of epithelioid cells with abundant eosinophilic cytoplasm, round to oval nuclei, and prominent nucleoli, surrounded by a fibrous stroma with no inflammatory infiltrate. No spindle cell component was detectable. The prominent feature was the formation of pseudoglandular structures appearing optically empty and bordered by epithelioid cells. No mitoses, prominent cellular atypia, and invasion or destruction of adnexal structures were detected (Fig. 2). Immunohistochemical study of epithelioid cells was negative for epithelial markers such as pan cytokeratin, but expressed the melanocytic markers S100 and melan-A (Fig. 2).