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Deficient Expression of Tumor Necrosis Factor Receptor Type 2 in the Endometrium of Women with Endometriosis

Problem: Tumor necrosis factor‐α (TNF‐α) is secreted mainly during the menstrual phase and has been suggested to play a role in induction of apoptosis in endometrial cells and menstrual shedding. TNF‐α receptor type 2 (TNF‐RII) is believed to play a central role in TNFα‐mediated cytotoxic, mitogenic, anti‐proliferative and apoptotic effects. The aim of this study was to assess whether TNF‐RII maybe expressed differentially in the endometrium of women with different degrees of endometriosis.