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High incidence of adnexotropism in cytotoxic cutaneous lymphomas

Primary cutaneous gamma‐delta T‐cell lymphoma (PCγδTCL) and primary cutaneous aggressive epidermotropic T‐cell lymphomas (PCAETCL) are rare aggressive cytotoxic cutaneous lymphomas (CyCL) often difficult to diagnose. Histopathologically, PCAETCL and PCγδTCL may resemble mycosis fungoides (MF) and the presence of adnexotropism in CyCL (CyCL) contributes to this diagnostic challenge, especially in the setting of atypical and double‐negative phenotypes.