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Synthesis and Application of Ag NPs@graphene Oxide Nanocomposite as an Electrochemical Sensor for Sweat Lactate Monitoring in Sports Medicine

In this study, a sensitive electrochemical sensor for detection of lactate was proposed. The sensor was developed based on GCE substrate coated by Ag NPs@GO/GCE. The morphological and structural properties of Ag NPs@GO/GCE were characterized using FESEM and XRD analysis, respectively. FESEM results confirmed a uniform distributed Ag NPs in GO nanocomposites. The sensor performance of the device was examined by amperometry and cyclic voltammetry. The electrochemical sensor exhibited a linear response to the lactate in phosphate buffer solution with a liner range and sensitivity of 10 to 600 μM and 16.5 μAcm mM, respectively. The concentration of lactate estimated by this sensor in real sweat samples was very close to the amount of injection which can be considered as a sensor for lactate measurement in sweat samples.