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Challenges in Diagnosing Childhood Tuberculosis.

Mycobacterium tuberculosis (Mtb) is the leading global killer from a curable infectious agent yet the true scope of disease in children is not known. In 2014, estimates approximated 1 million cases of childhood TB and 136,000 deaths. However, the actual number of cases disclosed to national TB programs were vastly different: only 36% of estimated pediatric TB cases were reported.1 Reasons behind the under-recognition and under-reporting are multifactorial, but all speak to the urgent need for improved TB diagnostics for children.