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Case of esophageal superficial neuroendocrine carcinoma suggestive of transformation from squamous cell carcinoma

A 69-year-old man was referred to our hospital for esophageal carcinoma. In July 2016, a 1-cm superficial whitish lesion was found (Figure 1a). In Feb 2018, it grew to 1.5 cm (Figure 1b) and it was squamous cell carcinoma (SCC) on biopsy. In April 2018, esophago-gastro-duodenoscopy (EGD) revealed it had developed a submucosal tumor (SMT)-like protrusion in the central part (Figure 1c).