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[Placental lactogen and estrogens in the amniotic fluid in normal pregnancy and in pregnancy complicated by hypertension in relation to the state of the newborn].

The study was carried out in 45 samples of amniotic fluid taken by amniocentesis from 21 hypertensive mothers (study group) and 24 healthy mothers (control group). In these samples the concentrations were determined of total oestrogens and human placental lactogen. In the evaluation of the state of the newborns the following was considered: 1) length and body weight, 2) status in the 1st minute of life (Apgar score). The results were subjected to statistical analysis. In hypertensive mothers during pregnancy HPL and total oestrogen concentrations were decreased. In the study group reduction of body weight and length was found. The general condition of the newborns in the 1st minute was similar in both groups.