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Antibiotic Therapy in Diabetic Foot Infection

Antimicrobial therapy of diabetic foot infection (DFI) is a controversial issue in medicine. The reasons for the controversy relate to the difficulties in diagnosis, in establishing the extent of infection, and in determining the causative micro-organisms. In addition, there is a lack of well-designed clinical studies investigating which is the optimal antimicrobial therapy. Because of the limited and controversial data, we approach DFI just as any other infection and its treatment, 1 and discuss the special situation for the DFI.