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Letter by Naqvi and Motallebi regarding article, "Left ventricular resynchronization is mandatory for response to cardiac resynchronization therapy".

To the Editor:

Bleeker et al1 propose that in patients selected on the basis of both electrical and a single mechanical dyssynchrony measure derived from maximum delay during left ventricular (LV) ejection between peak systolic velocities among 4 basal LV segments, immediate resynchronization (of at least 20%) after cardiac resynchronization treatment (CRT) predicts reduction in LV end-systolic volume by at least 10% at 6-month follow-up. The editorial accompanying the article by Bleeker and colleagues2 appropriately “cautions” against relying on a single “dyssynchrony” measure and on “early resynchronization” …