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EFFECT OF ALKANNA FRIGID EXTRACTS ON 3T3 FIBROBLAST CELL PROLIFERATION

Fibroblasts are the major cell types found in the granulation of wound tissue and play a key role in wound healing. In this study we examined the effects of the sequential root extracts of Alkanna frigida on the stimulation of the growth of fibroblasts as an aspect of promotion of wound healing by an in vitro study on Embryonic Swiss Mouse Fibroblast (3T3) Cells. Results showed that all the tested extracts were able to increase proliferation of 3t3 cells. Nhexan and chloroform extracts had the most effect on fibroblast proliferation.