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EP02.02: Placental chorioangioma: ultrasound diagnosis and management of a complex pregnancy: EP02.02: Placental chorioangioma: ultrasound diagnosis and management of a complex pregnancy

Objectives: To determine the relationship between mid-trimester ultrasonographic length of the uterine cervix and neonatal respiratory distress syndrome. Methods: In this retrospective observational study, the cervical length (cm) was measured by transvaginal ultrasound at 19–25 weeks. Demographic and perinatal records were reviewed between Jun 2011 and Mar 2014 and statistically analysed for the prediction of neonatal respiratory distress syndrome (RDS). Data were compared between RDS and non-RDS groups. Statistical analyses were performed using SPSS 13.0 (SPSS, Inc., Chicago, IL, USA). Two-sided tests were used and a P < 0.05 was considered statistically significant in all analyses. Results: A total of 539 women were included for analyses. There was no difference in demographic characteristics between RDS and non-RDS groups. In RDS group, gestational age at delivery was lower, the rate of Caesarean delivery was higher and neonatal birthweight was lower (P < 0.001, 0.001 and <0.001 respectively) Women with neonatal RDS had shorter mid-trimester cervical length (P = 0.017). In a multivariate logistic regression analysis to adjust other factors such as birth age, birthweight and delivery mode, the cervical length remained significant with birth age (odds ratio, 0.405; 95% confidence interval, 0.183–0.895; P = 0.025). Delivery mode was marginally significant for neonatal RDS. Conclusions: Our data shows that the short cervical length on transvaginal ultrasound at mid-trimester pregnancy can be associated with neonatal RDS. The cervical length could be a reasonable and useful ultrasonographic marker to predict neonatal RDS infants. The data will be useful for obstetric counselling of high risk pregnancy with neonatal complications.