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OC07.05: Maternal cardiac function in patients with mild and severe pre‐eclampsia compared with normal pregnant women

demographics and pregnancy outcome were obtained from obstetric records. Descriptive statistics was performed. Mean gestational age at delivery and fetal birthweight with z-scores were compared between groups. Prevalence of small for gestational age fetuses (SGA, <5th percentile) and preterm birth (<37 weeks) was calculated and compared. Mann-Whitney U, independent samples t-tests and chi-square test were used. Results: A total of 35,194 women were included at a mean gestational age of 21.5±1.1 weeks. UtAD impedance was normal in 30,915/35,194 (87.8%) women and elevated in 4,279/35,194 (12.2%). In the group with normal UtAD 30,570/30,915 (98.9%) had a live birth. Intrauterine demise or neonatal death was reported in 345/30915 (1.1%). In the group with raised UtAD, 4,159/4,279 (97.2%) women had a live birth, whereas intrauterine demise or neonatal death was reported in 120/4,279 (2.8%). Mean gestational age at delivery was 39.1±2.4 and 38.1±3.3 weeks in the normal and raised UtAD group, respectively (p=0.001). Mean birthweight z scores were 0.06 and -0.33 in the normal and abnormal UtAD groups, respectively (p=0.001). The prevalence of SGA was 1,221/30,915 (3.9%) in the normal and 600/4,279 (14%) in the raised UtAD group (p=0.001). The prevalence of preterm birth was 2,534/3,0915 (8.2%) and 756/4,279 (17.7%) in the two groups (p=0.001). Conclusions: Raised UtAD at the anomaly scan is associated with an increased rate of intrauterine demise or neonatal death. Fetal birthweight is lower in women with raised UtAD.