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Fatigue and quality of life after 2 weeks post discharge in post-COVID-19 subjects: A cross-sectional study

Context: Coronavirus disease (COVID-19) pandemic affected a large number of individuals globally. Fatigue follows other viral infections; many of the hospitalized persons with a moderate to severe form of COVID-19 illness report residual symptoms, contributing to activity limitations. Aim: To assess the fatigue and quality of life (QOL) in post-COVID-19 subjects, 2 weeks after discharge. Settings and Design: An observational study was conducted on COVID-19 subjects, 2 weeks after discharge from tertiary care hospitals. Methodology: Subjects meeting the inclusion and exclusion criteria were recruited. Three hundred and sixteen subjects were contacted by phone call, and verbal consent was taken. The outcome measures used were the Fatigue Assessment Scale and World Health Organization QOL-BREF scale. Statistical Analysis Used: Statistical measures such as mean and standard deviation and descriptive statistics such as percentage analysis and Pearson's correlation test were used. Results: The correlation between fatigue and QOL was statistically significant, with a nonlinear association (P < 0.05). Hospital stay and fatigue were directly related, which was significant. Linear association demonstrated that age was negatively related to QOL and positively associated with fatigue. Conclusion: COVID-19 subjects were more likely to have fatigue and low health-related QOL even after 2 weeks of discharge. There was a significant nonlinear correlation between fatigue and QOL in COVID-19 survivors.