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Hybrid neurofibroma/schwannoma in neurofibromatosis type I exhibiting high FDG uptake in PET imaging

A 50-year-old man with neurofibromatosis type 1 (NF1) presented with a 3-year history of a gradually enlarging, painful tumor on his left thigh. He had undergone surgical procedures for neurofibromas on his neck and cervical spine in the 5 years prior to his admission. He had a family history of NF1. A dermatological examination revealed a dome-shaped, elastically firm, gray-brownish tumor measuring 8 × 7 cm on the left thigh (figure 1A). There was no inguinal lymphadenopathy. Widespread cafe-au-lait [...]