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Migration and colonization of leukemic lymphoblasts in AKR and HSS inbred mice followed by serial enzyme determinations.

After transplantation of AKR and HSS leukemic cells into AKR and HSS inbred mice as well as into their hybrids, the distribution and proliferation of the cells depend on the host organism. The energy production and glycolytic enzyme activity of the settled cells differ from that of the injected leukemic cells. It may be supposed that either the cell transplantation was carried out with a heterogeneous cell population or the cells of the host organism started to dedifferentiate.