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Suzuki Cross Coupling Reaction- A Review

Suzuki cross coupling reaction is one of the most famous reaction in the field of chemistry. It is a very effective method for making carbon – carbon bonds. It has been extensively utilized in the synthesis of many carbon molecules including the most complex ones. It also find application in the synthesis of compounds of biological sources like (+)-dynemicin, Adragmacidin F, Flurbiprofen, Felbinac, Fenbufen, Difunisal, Aporphinoids, Oximidine II, Nemertelline, Gymnocin A, Palytoxin, Michellamine, CP263,114, Halenaquinone, Brevetoxin, Yuehchukene, caparratriene etc which have been synthesized using the same reaction along with some other organic compounds. The present review article emphasis on carbon-carbon bond formation via cross coupling reaction, mechanism and applications in a natural product synthesis. © 2011 IGJPS. All rights reserved