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[Adenylate cyclase activity of the plasma membranes of lung tissue at lengthy periods following non-lethal gamma-irradiation of rats].

Basal and stimulated activity of adenylate cyclase (cyclizing ATP-pyrophosphate lyase, E.C. 4.6.1.1., AC) in plasma membranes of pulmonary tissue was being studied during a year after fractionated irradiation of rats (2 GyX3). Basal and hormone-stimulated activity of AC was shown to vary significantly from normal 6 and 12 months after irradiation. The exposed membranes responded differently to AC activation by isoproterenol and F-.