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Keratoplasty in aphakic eyes with corneal edema: results in 100 cases with 10-year follow-up.

Penetrating keratoplasties were performed in 100 patients with bullous keratopathy and aphakia. In 85% of cases, edema was due to Fuchs' dystrophy. Cases were divided into eyes with good, fair, and poor prognosis, depending on the presence of glaucoma, anterior segment pathology and corneal vascularization. The three combined groups had 78% clear grafts during the first year, but when results were correlated with the prognostic groups, there were 85% of clear grafts in Group I, 78% in Group II, and 60% in Group III. The number of clear grafts dropped prominently in Groups II and III after the second year. At the end of ten years, 7 of 15 clear grafts corresponded to Group I. The most common possible causes of graft failure not related to donor tissue were: Vitreous in contact with the graft, glaucoma, and anterior segment pathology.