{'fraction_non_alphanumeric': 0.03809040121889284, 'fraction_numerical': 0.017267648552564754, 'mean_word_length': 6.01067615658363, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 2, 'lorem ipsum': 0, 'www.': 2, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 1, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
British HIV Association guidelines on the management of opportunistic infection in people living with HIV: The clinical management of Candidiasis 2019

1 Methods 1.1 Guideline development process Full details of the guideline development process, including conflict of interest policy, are outlined in the BHIVA guideline development manual which was last updated in 2014 (see https://www.bhiva.org/file/jgCacHqmuxZFL/GuidelineDevelopmentManual.pdf). The scope, purpose and guideline topics were agreed by the writing group. Questions concerning each guideline topic were drafted and a systematic literature review undertaken by an independent information scientist (Jacoby Patterson). The search questions (the populations, interventions, comparators and outcomes [PICOs]), are outlined in Appendix 1, and the search strategy in Appendix 2. Details of the methodology can be found on the BHIVA website (https://www.bhiva.org/file/5d514ec9b503d/OI-guidelines-methodsgeneral.pdf). For the current guidelines, PubMed, Medline, Embase and the Cochrane Library were searched for English language publications between January 2010 and March 2018, the period since the last candidiasis guidelines published by BHIVA. Searches were conducted using the following terms: HIV or AIDS and candidosis, candidiasis, Candida spp., Candida albicans, non-albicans Candida, oropharyngeal candidiasis, candida (o)esophagitis, vulvo(-)vaginal candidiasis or mucosal candidiasis. Abstracts from selected conferences (BHIVA, Conference on Retroviruses and Opportunistic Infections, Interscience Conference on Antimicrobial Agents and Chemotherapy and Infectious Diseases Society of America) were also searched for the same period. Articles already cited in the 2011 BHIVA/British Infection Association (BIA) guidelines for the treatment of opportunistic infection in HIVseropositive individuals were also considered for the current guidelines. Definitions used are summarised in Appendix 3.