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935 CENTRAL BLOOD PRESSURE ESTIMATED BY OMRON HEM-9000AI IN THE GENERAL POPULATION: ESTABLISHMENT OF REFERENCE AND NORMAL VALUES

Objectives: Despite the general agreement that central blood pressure (BP) better relates to cardiovascular target organ damages and cardiovascular events than brachial BP, its clinical use has been limited without established reference values. The present study was designed to establish reference and normal values for central BP estimated by Omron HEM-9000AI (Omron Healthcare, Kyoto). Design and Methods: A cross-sectional study was performed in 10756 subjects without overt cardiovascular disease (male 61.1%, mean age 55.3 ± 12.5 years). Of these, 7348 subjects received no anti-hypertensive, anti-diabetic, or lipid-lowering drug treatment, constituting the reference value population. Subjects with no cardiovascular risk factors and that were in the optimal or normal brachial BP categories (n = 2672) were selected to establish normal values. Results: Estimated central BP was significantly correlated with age and brachial BP and, thus, reference and normal values were established according to age decade (table) and brachial BP categories. Reference values (mmHg, mean ± 2SD) were 113.5 ± 18.6 in optimal, 128.6 ± 14.6 in normal, 138.4 ± 16.8 in high normal, and 155.3 ± 27.9 in hypertension categories and normal values were 112.6 ± 19.2 in optimal and 129.2 ± 14.9 in normal BP categories. Table. No title available. Conclusions: The present study is the first to establish reference and normal values of central BP estimated by the Omron HEM-9000AI, making an important step toward implementing the clinical use of central BP in the diagnosis and management of hypertension.