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Accelerated Generation of Spatiotemporal Atlas through Fast Template Matching

A spatiotemporal atlas refers to a standard image sequence that represents the general motion pattern of the targeted anatomy across a group of subjects. Recent years have witnessed an increasing interest in using spatiotemporal atlas for scientific research and clinical applications in image processing, data analysis and medical imaging. However, the generation of spatiotemporal atlas is often time-consuming and computationally expensive due to the nonlinear image registration procedures involved. This research targets at accelerating the generation of spatiotemporal atlas by formulating the atlas generation procedure as a multi-level modulation (M-ary) classification problem. In particular, we have implemented a fast template matching method based on singular value decomposition, and applied it to generate high quality spatiotemporal atlas with reasonable time and computational complexity. The performance has been systematically evaluated on public accessible data sets. The results and conclusions hold promise for further developing advanced algorithms for accelerating generation of spatiotemporal atlas.