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Recent Advances in DNA Biosensors

Traditional DNA sequencing technologies are complicated and expensive, which greatly hinders its application. With the development of DNA biosensors, different biosensors based on different mechanisms have been put into use in DNA sequencing, biomacromolecule detecting and many other fields. In this review, three different kinds of biosensing methods including solid-state nanopores, fluorescent biosensors and electrochemical biosensors, will be given respectively. Specifically, their advantages, mechanism, applications and existing problems are discussed in detail. And also, prospects for future development will be outlined in this paper.