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SIMULATED EPICARDIAL POTENTIAL MAPS WITH A MEMBRANE-BASED BIDOMAIN MODEL OF THE HUMAN HEART

Computer models of cardiac activation are constantly growing in terms of accuracy and resource usage. The availability of powerful parallel computers has allowed us to create a program that computes intracellular and extracellular potentials in a model of a complete human heart, basing on a model of the ionic currents in the cell membrane and the bidomain model of cardiac tissue. Potentials were computed on a regular finite-difference grid of 50 million nodes, using a forward-Euler approximation for the membrane potential and a BiCGStab linear-system solver with a parallelized incomplete-LU preconditioner to solve for the extracellular potentials. Realistic extracellular signals and epicardial potential distributions were obtained. In memory of Prof. Ramesh M. Gulrajani (1944–2004).