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Acute Effects of Watermelon on Vascular Function and Serum Antioxidant Capacity

Vascular dysfunction is an early independent predictor of future cardiovascular disease, the leading cause of death among women in the United States. Vascular endothelial function declines with age, largely due to decreased nitric oxide (NO) and increased oxidative stress. It is plausible that multiple bioactive compounds naturally found in watermelon (lycopene, ascorbic acid, arginine, citrulline, and glutamine) may act in synergy to improve endothelial function by increasing bioavailable NO and antioxidant capacity.