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MORPHOGENESIS AND CANCER

M. J. DENTON, Registrar, Department of Chemical Pathology. Victoria; Mr G. Kaufman, Commonwealth Serum Laboratories, Parkville, Victoria; Dr J. V. Lloyd, Institute of Medical and Veterinary Science, Adelaide, South Australia; Dr J. Margolis, Blood Transfusion Service, Sydney, New South Wales; Mr E. C. Mason, Blood Transfusion Service, Brisbane, Queensland; Dr K. A. Rickard, Royal Prince Alfred Hospital, Carnperdown, New South Wales. The study demonstrated clearly the large variations between the results of different laboratories, encountered even when assaying a Factor VIII concentrate against the International Standard (which is also a concentrate). The geometric mean potency results for the reference preparation varied from 0·6 to 1·6 IU per vial, in different laboratories. Similarly, in the four laboratories in which the assays were run in comparison with pools of normal plasma, the geometric mean potencies found for these pools varied from 0·5 to 1·2 IU/mI. Supplies of the reference preparation will be made available free of charge to workers in the field of blood coagulation, upon written request to the Director of these Laboratories. A full report on the collaborative study is also available. Commonwealth Serum Laboratories, 45 Poplar Road, Parkville, Vic. 3052.