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Caffey's disease (Infantile cortical hyperostosis): Case Report, MRI findings, and review of the literature

Caffey's disease or infantile cortical hyperostosis is a rare condition that affects infants and is mostly a self-limiting condition. It presents as an acute inflammatory process of the periosteum and the surrounding soft tissues. Affected infants present with irritability and fever. In many cases, the diagnosis gets delayed because of the rarity of the condition and the fact that it mimics a wide range of diseases that are more common and more serious including acute osteomyelitis, bone tumors, scurvy, hypervitaminosis A, infantile malignant osteopetrosis, and child abuse. This case is reported to get the awareness of the physicians about the disease, its existence in our population, presentation, and important differential diagnoses and management and to show the important role of magnetic resonance imaging in the management.