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Ketamine-induced dysrhythmia and its antagonism: a case report.

Ketamine is normally considered as being anti-dysrhythmic. A case report is presented here in which small subanaesthetic doses of ketamine were administered to reinforce spinal analgesia. Initial doses were followed by a dysrhythmia, which appeared to be repeatedly counteracted by further small doses of the drug. The cardiac pharmacology of ketamine is discussed, as is the relevance of the chance finding of mitral valve prolapse.