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The pacemaker story: A cold heart spin-off.

It is 1949. Visualize, if you will, Room 64 in the basement of the Wanting Institute in Toronto home of the cardiovascular surgical experimental laboratory. The room is 23 x 14 feet. A small, high window is below ground level. The adjoining Room 65 has recently been acquired. This is stated very simply, but the process of acquiring extra space in an active university building requires a tour de force. To obtain space from someone in your own division is very difficult; from another division in the same department it is next to impossible; and to acquire space from another department is a meritorious accomplishment that has usually involved the dean of the faculty, at least two departmental heads, several committees, cajoling, entreaty, kindly offers, gifts, and even veiled threats. One must have several key people "on side". It is seldom successful as a single-handed operation. Room 65 was, in fact, an acquisition from another department. It was immediately converted into what we seriously called an operating room, though without the usual tiled wall and floors. It became the busiest large-animal laboratory in the university, and it still is. Animals were housed on the top floor. To find Rooms 64 and 65, a visitor first proceeded down a stairway into a dimly lit basement with cement floor and brick walls. It was necessary to pick one's way carefully