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A large right atrial thrombus penetrating through a patent foramen ovale in a patient with Prothrombin G2120 Mutation

Abstract: The Prothrombin mutation G2021 alone is considered a minor
risk factor for thromboembolism, but thromboembolic events are more
likely in the presence of additional risk factors. We report on a
44-year-old female with an atrial thrombus causing pulmonary embolism
and transiting through a patent foramen ovale. The thrombus was
extracted by open heart operation. The patient had a family history for
thromboembolic events. Further diagnostic after surgery found the
patient positive for the Prothrombin mutation G2021, but not for the
Factor V Leiden mutation. After surgery, a permanent oral
anticoagulation has been started.