{'fraction_non_alphanumeric': 0.024891774891774892, 'fraction_numerical': 0.012987012987012988, 'mean_word_length': 5.379310344827586, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
[New strategies for the etiologic study of interstitial pneumonia: familial registration and sib-pair analysis].

Etiology of idiopathic interstitial pneumonia (IIP) remains unknown. While many studies focused on the analysis of individual patients, available information is limited for the further study. Having experienced a case, 3 of 5 brothers suffered from IIP and 2 of them complicated with lung cancer, intensive familial history taking with chest photos and functional information for fibrotic lung was performed. Among 37 families in which at least 2 members were examined, 14 families (37.8%) had minimum 2 members with fibrotic lungs. Unexpectedly high familial accumulation of fibrotic lung indicates the possibility of multi-gene involvement for the pathogenesis. We need to start group studies to register sib-pairs with fibrotic lungs and systematize the automated genetic analysis for the responsible genes.