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Molecular and Cellular Biophysics

WHAT IS LIFE? Hierarchical Organization of Knowledge General Characteristics of Living Systems Artificial Life Biological Information, Information Processing, and Signaling Origin of Life Emergence, Intelligence, and Consciousness WHAT ARE THE MOLECULES OF LIFE? Nucleic Acids, DNA, RNA Generalized Ester Bonds Directionality of Chemical Bonds Types of Interatomic Interactions The Hydrogen Bonds and Hydrophobic Interactions Amphipatic Molecules in Water Environments Structure of Proteins Structure of Nucleic Acids WHAT IS A BIOLOGICAL CELL? Cytoplasm Cytoskeleton Tubulin Isotype Homology Modeling Anisotropic Elastic Properties of Microtubules Centrioles, Basal Bodies, Cilia, and Flagella Networks and Meshworks of Protein Filaments, Stress Fibers, and Tensegrity Cell Nucleus and Chromosomes Mitochondria and Proton Pumps: Energy Generation and Utilization in the Cell Cytochrome Oxidase Enzymes Membranes and Vesicles Motor Proteins and Their Role in Cellular Processes Directed Binding as a Model of Kinesin Walk Other Structures Large Polar Molecules WHAT ARE LIFE PROCESSES? Oxidative Phosphorylation Diffusion Processes Proton Transport and Bioenergetics Electronic and Ionic Conductivities of Microtubules and Actin Filaments Mechanisms of Exciton Energy Transfer in Scheibe Aggregates Conformational Transitions in Proteins Vesicle Transport and Molecular Motors Muscle Contraction Subcellular Structure Formation Cell Division GLOSSARY INDEX Questions, Problems, and References appear at the end of each chapter.