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[Changes in the activity of cortical neurons after administration of biogenic amines].

Effects of different neurotransmitters on activity of cortical neurons were studied in immobilized rabbits. The final effect of serotonin and noradrenaline, in contrast to acetylcholine and GABA, depended on initial functional level of the neurons. Various types of cortical neurons responses to the same monoaminergic stimuli are described. The comparative analysis of the data obtained suggests participation of serotonin and noradrenaline in neurochemical organization of positive and negative reinforcement, resp.