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[Effect of progestagens administered during pregnancy on histochemical reaction in fetal liver].

Fetal liver was examined in rats, whose mothers during pregnancy received Turinal (firm: Chemical Works of Gedeon Richter LTD Budapest, Hungary) in a dosage of 0.5 mg/kg BW in the experimental group I and 1 mg/kg BW in the experimental group II. Reaction to the activity of succinate dehydrogenase, lactic dehydrogenase, acid phosphatase, glucose-6-phosphatase, PAS-reaction (Periodic acid Schiff reaction) and hematoxylin-eosin staining were carried out. Changes in the activity of examined enzymes and PAS-reaction in fetal liver depending on dosage were observed. These changes testify to a large influence of administered hormone on metabolism of developing fetal liver.