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AIDS and hemophilia.

The acquired immunodeficiency syndrome (AIDS) in the hemophilic population has been devastating. The first example of transfusion-induced AIDS was diagnosed in a patient with hemophilia who died of Pneumocystis carinii pneumonia in 1982. So far, studies of the pattern of disease in patients with hemophilia show that infectivity is high in patients with severe hemophilia who receive frequent transfusions (the prevalence of antibodies against the human immunodeficiency virus [HIV] in such patients ranges from 75 to 90 percent among adults and is somewhat lower in children [58 percent]); fewer go on to have AIDS-related complex and AIDS (20 percent and . . .