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Modeling and analysis of the dynamics of HIV/AIDS with non-singular fractional and fractal-fractional operators

In the present study, we analyze the dynamics of HIV/AIDS epidemic model with fractional and the new definition of a nonlocal fractal-fractional derivative in the Atangana-Baleanu-Caputo (ABC) sense. The proposed model is initially formulated with the help of classical integer-order differential equations and then the ABC fractional derivative is used to obtain the fractional HIV/AIDS model with arbitrary order p 1. Then we present some basic properties including equilibria and the basic reproduction number of the model. The local and global stability of the fractional model at disease free equilibrium is shown and it is found that the model is stable when the threshold quantity is less than 1. Further, an efficient numerical approach is applied to present an iterative scheme for the fractional model and present graphical results for various values of p 1. After this, we make use of the new fractal-fractional operator to formulate the HIV/AIDS model in the ABC sense. The uniqueness and existence of the solutions are shown through the Picard-Lindelof theorem. Furthermore, we derive an iterative scheme of the fractal-fractional ABC model using a novel numerical method based on Adams-Bashforth fractal-fractional approachand depicts detailed graphical results for many values of fractional and fractal orders p 1 and p 2 respectively. The simulation results show that the HIV/AIDS model with the novel fractal-fractional operator provides biologically more feasible analysis than that of the classical fractional and integer-order models.