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A case of bronchogenic cyst with high production of antigen CA 19–9

A 35‐year‐old man was hospitalized with complaints of retrosternal pain and high fever. A chest radiograph showed a large round mass in the mediastinum. Of the several tumor markers in the serum tested, only CA 19‐9 was elevated. Thoracotomy revealed a cystic mass with purulent hemorrhagic materials. Histologically the cyst was lined by bronchial epithelium with no evidence of malignancy. The high level of CA 19‐9 in the cystic fluid, and positive immunohistochemical staining of the bronchial glands in the cyst wall for CA 19‐9 indicated that the elevated serum level of CA 19‐9 originated from the bronchogenic cyst after its infection.