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Outpatient laparoscopic management of ectopic pregnancy with a local methotrexate injection.

Nine patients with unruptured tubal ectopic gestations were treated as outpatients utilizing a laparoscopically directed injection of methotrexate into the tubal mass. The initial quantitative serum human chorionic gonadotropin values ranged from 34 to 17,100 mIU/mL. Eight of nine subjects had complete resolution of the pregnancy over the ensuing 10-33 days; the remaining patient, with plateauing human chorionic gonadotropin levels, required a laparotomy.