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In Vitro-In Vivo Comparison of Prosthetic Heart Valve Performance


 The present investigation is focused on the significance of pulsatile in vitro flow measurements in the vicinity of prosthetic bileaflet heart valves at the aortic position. With the help of a pulse duplicator system and of optical LDA-technique, mean flow data were collected first. Then the blood flow patterns downstream of the same valve type was visualized in vivo by using a novel MRI-procedure. The application of both techniques under pulsatile flow conditions made the in vitro - in vivo comparison possible for the first time.