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Clinics in Haematology, Vol. 8, No. 2. Cellular Dynamics of Haemopoiesis

Clinics in Haematology, Vol. 8, No. 2. Cellular Dynamics of Haemopoiesis Edited by L. G. LAJTHA. Pp. viii+310, illustrated. W. B. Saunders, London, Philadelphia and Toronto, 1979. £8.25. Medical research often advances in great surges. We seem to be past such a surge in immunology. On the other hand,we are clearly on the upward slope of activity in relation to haemopoietic stem cells and hence this volume of Clinics in Haematology entitled Cellular Dynamics of Haemopoiesis is very timely. The book is directed more to the scientist than the physician and will be of most use to research workers in this exciting area. The field is still dominated by problems of methodology and this is discussed in relation to the different cell lines. Sections deal with pluripotent stem cells, genetic anaemias in mice, granulocyte-monocyte precursors as assessed in semi-agar culture, regulation of granulopoiesis, erythroid stem cells in relation to human disease, erythroid and granulocytic kinetics, megakaryocytopoiesis, lymphopoiesis, surface markers and cell sorters, haemopoietic regulation and leukaemic cells. Some sections may not be easy to read other than by those engaged in the field; and those who, like the reviewer, look for an idiot's guide to stem cells and their regulation, had better start with a simpler description of events before graduating to this more advanced volume.