{'fraction_non_alphanumeric': 0.017982017982017984, 'fraction_numerical': 0.006993006993006993, 'mean_word_length': 4.928994082840236, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Osteogenesis imperfecta type II in one of a pair of twins.

variety of biochemical defects in type I procollagen resulting in disruption of triple helical conformation and procollagen suicide are responsible for the clinical features(2). Some cases are autosomal recessivtf but many are new dominant mutations. A large majority of patients die in early neonatal period or infancy but the incidence in general population is kept constant as a result of new mutations. It has been estimated that the mutation rate in osteogenesis imperfecta is 4 x 10 per gene per generation(3). The occurrence of osteogenesis imperfecta in one of a pair of twins would be a rare chance association. On extensive review of literature we could come across only two such reports(4,5). The purpose of this communication is to describe our experience of such a case, emphasize the inclusion of long bone evaluation in the 'routine' antenatal ultrasound examination and raise the management dilemma posed by such a situation.