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The topographical and laminar organization of the presubiculum's projection to the ipsi‐ and contralateral entorhinal cortex in the guinea pig

This is a detailed report of a previously described projection from the presubiculum to the entorhinal are (Shipley,1974). The terminal degeneration in the entorhinal area is specifically confined to the outer three layers of this cortex. The projection is topographically organized and confined to dorsal and medial parts of the entorhinal area. A similarly organized projection courses via the dorsal psalterium (dorsal hippocambal commissure) to the contralateral entorhinal area. Thus each presubiculum has an orgainzed terminal pathway to the entorhinal cortices of both hemisphers.