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Intraoperative Antibiotics in the Prevention of Experimental Dacron® Graft Infection

Moore and colleagues have shown that newly inserted Dacron-) vascular grafts are very susceptible to infection from circulating bacteria.’ Since S. Martin Lindenauer demonstrated in 1967 that prophylactic use of penicillin prevented the infection of Teflon patch grafts in a group of five dogs, experiments have been designed to justify the widespread use of prophylactic antibiotics in vascular surgery.’ 6