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Association of Novel Gene Polymorphisms RRM1 −756T>C and −269 C>A With Breast Cancer

Genetic variants are reported to play an important role in the susceptibility of breast cancer. Ribonucleotide reductase 1 (RRM1) is suggested to play an essential role in the regulation of cancer development. The purpose of this study was to identify novel gene polymorphisms of RRM1 −756T>C and RRM1 −269 C>A specific to patients with breast cancer and healthy controls.