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Non‐surgical periodontal therapy reduces salivary adipocytokines in chronic periodontitis patients with and without obesity

AIM
The aim of the present study was to assess the effect of scaling and root planing (SRP) on periodontal parameters and whole salivary resistin and interleukin (IL)-6 levels in chronic periodontitis (CP) patients with and without obesity.


METHODS
Participants were divided into two groups; group 1 included obese and non-obese individuals with CP; and group 2 included obese and non-obese individuals without CP. In both groups, bleeding on probing (BOP) and probing depth (PD) ≥4 mm and whole salivary resistin and IL-6 levels were measured using enzyme-linked immunosorbent assay at baseline and 6 months after SRP. The number of missing teeth was counted, and marginal bone loss was measured on digital panoramic radiographs at baseline and 6 months' postoperatively.


RESULTS
BOP was significantly higher among obese patients in group 1 than obese (P < .001) and non-obese (P < .001) individuals in group 2. At 6 months' follow up, BOP (P < .001) and PD ≥4 mm (P < .001) were significantly lower among obese and non-obese patients in group 1 than their respective baseline values. At 6 months' follow up, BOP (P < .001) and PD ≥4 mm (P < .001) were significantly higher among obese and non-obese individuals in group 1 compared with individuals in group 2.


CONCLUSION
SRP is effective in reducing periodontal inflammation in CP patients with and without obesity. CP seems to be the primary factor that influences periodontal status and the expression of resistin and IL-6 levels in obese and non-obese patients.