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Atrophic gastritis in dyspeptic patients.

Gastric biopsy was performed on 107 dyspeptic patients over the age of 40 years. Varying degrees of atrophic gastritis were found in 65 per cent, the remainder having normal gastric mucosa. The incidence was lowest in those with duodenal ulcer, intestinal metaplasia not being found in any of this group.Hypochlorhydria was found in 77 per cent of those with atrophic gastritis and in 13 per cent of those with normal mucosa. The accuracy of barium meal, gastroscopy and gastric photography in discriminating between those with atrophic and those with normal gastric mucosa was less accurate.No significant haematological dilferences were found between the two groups of patients. Parietal cell antibodies were detected in the sera of 15 per cent of those cases with atrophic gastritis.