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Drugs for disruptive features in dementia

It is estimated that around 750,000 people in the UK have dementia and, of these, 60% will have behavioural changes or psychological symptoms.1–3 These features tend to occur in clusters, of which the five most readily recognised are characterised by aggression, apathy, depression, psychomotor agitation or psychosis.4 Here, we review the place of drug therapy in the management of patients in whom these features are disruptive.