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[Reactivity of the microcirculation bed of the small intestine mesentery in experimental dehydration in rats].

The state of mesenteric microcirculatory bed has been studied in male rats 3, 6 and 12 days after the beginning of alimentary dehydration. It has been revealed that vascular, intravascular and extravascular changes were of particular importance. Spastic reactions of arterioles and precapillary arterioles, the activation of arteriolo-venular shunting and the reduction in capillary circulation accompanied by diminution of all microvascular diameters were among the most marked vascular phenomena. The intravascular changes were represented by decreased blood flow rate, erythrocyte aggregation and leucocyte adhesion. The extravascular phenomena were characterized by the appearance of local hemorrhages.