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THE USE OF THE E‐ROSETTE AS A TEST FOR REMISSION IN GRAVES’DISEASE TREATED WITH ANTITHYROID DRUGS

E‐rosettes (T‐lymphocytes) have been demonstrated to be increased in the peripheral blood of patients with untreated Graves’disease and decreased when these patients go into remission induced by antithyroid drugs. In patients similarly treated but not in remission, a high percentage of E‐rosettes persisted. The degree of suppression by T3 of the thyroidal 131I uptake correlated well with the percentage of E‐rosettes. We suggest that E‐rosette counts may prove to be a useful test for detecting remissions in thyrotoxic patients treated with antithyroid drugs.