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A dual mesh reconstruction method for simultaneous reconstruction of optical absorption and scattering distributions with ultrasound localization

In this paper, we report simultaneous reconstruction of absorption and scattering heterogeneities using a dual mesh scheme based on finite element method (FEM). Column normalization has been applied to the weight matrix obtained from FEM forward model to correct the depth dependent problem and to alleviate the crosstalk between the absorption coefficient and scattering coefficient. With this approach, phantom targets with both absorption and scattering heterogeneities can be reconstructed with good contrast and resolution. With this approach, the contrast between malignant breast cancers and benign lesions can be further improved compared with that obtained from the modified Born approximation, where the bulk reduced scattering coefficient has been used for reconstructing absorption heterogeneities.