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Modulation of temperature on optical properties of rat skin in vivo

Local optical properties of tissue measurement system combined with a temperature control setup were used to investigate temperature-induced changes in optical properties of rat skin in vivo. The temperature of skin was maintained at 32°C, 35°C, 38°C and 41°C for more ten minutes, respectively. And the system composed a single wavelength (1310nm), multi-arrays optical probe with the separations of source-detector less than 1.25mm, was introduced to measure the reflectance of skin. The results showed that the reflectance at higher temperature was less than that at lower temperature. Further more, the optical properties were calculated. The higher temperature, the more both reduced scattering coefficient and absorption coefficient decreased. It means that temperature rise will induces a decrease in attenuation coefficient, and increase the penetrability of light. Research on temperature effect of skin may be helpful to optical clearing technique.